Alan Faden, M.D. - Publications

Affiliations: 
Georgetown University, Washington, DC 
Area:
traumatic brain injury, spinal cord injury

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Barrett JP, Henry RJ, Ann Shirey K, Doran SJ, Makarevich OD, Ritzel RR, Meadows VA, Vogel SN, Faden AI, Stoica BA, Loane DJ. Interferon-β plays a detrimental role in experimental traumatic brain injury by enhancing neuroinflammation that drives chronic neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32029532 DOI: 10.1523/JNEUROSCI.2516-19.2020  1
2020 Bhat S, Henry RJ, Blanchard AC, Stoica BA, Loane DJ, Faden AI. Enhanced Akt/GSK-3β/CREB signaling mediates the anti-inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice. Journal of Neurochemistry. e14954. PMID 31926033 DOI: 10.1111/jnc.14954  1
2019 Ritzel RM, Li Y, He J, Khan N, Doran SJ, Faden AI, Wu J. Sustained neuronal and microglial alterations are associated with diverse neurobehavioral dysfunction long after experimental brain injury. Neurobiology of Disease. 104713. PMID 31843705 DOI: 10.1016/j.nbd.2019.104713  0.6
2019 Sabirzhanov B, Matyas J, Coll-Miro M, Yu LL, Faden AI, Stoica BA, Wu J. Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice. Cell Death & Disease. 10: 839. PMID 31685802 DOI: 10.1038/s41419-019-2079-y  0.84
2019 Sarkar C, Jones JW, Hegdekar N, Thayer JA, Kumar A, Faden AI, Kane MA, Lipinski MM. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. 1-20. PMID 31238788 DOI: 10.1080/15548627.2019.1628538  0.68
2019 Ritzel RM, Doran SJ, Glaser EP, Meadows VE, Faden AI, Stoica BA, Loane DJ. Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice. Neurobiology of Aging. 77: 194-206. PMID 30904769 DOI: 10.1016/j.neurobiolaging.2019.02.010  1
2019 Sabirzhanov B, Li Y, Coll-Miro M, Matyas JJ, He J, Kumar A, Ward N, Yu J, Faden AI, Wu J. Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: participation of IL-10/miR-155 pathways. Brain, Behavior, and Immunity. PMID 30807841 DOI: 10.1016/j.bbi.2019.02.024  0.68
2018 Kumar A, Henry R, Stoica B, Loane D, Abulwerdi G, Bhat S, Faden A. Neutral Sphingomyelinase Inhibition Alleviates LPS Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury. The Journal of Pharmacology and Experimental Therapeutics. PMID 30563941 DOI: 10.1124/jpet.118.253955  0.76
2018 Aubrecht TG, Faden AI, Sabirzhanov B, Glaser EP, Roelofs BA, Polster BM, Makarevich O, Stoica BA. Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury. Cell Death & Disease. 9: 1121. PMID 30401820 DOI: 10.1038/s41419-018-1156-y  0.84
2018 Doran S, Ritzel R, Glaser E, Henry R, Faden A, Loane DJ. Sex differences in acute neuroinflammation after experimental traumatic brain injury are mediated by infiltrating myeloid cells. Journal of Neurotrauma. PMID 30259790 DOI: 10.1089/neu.2018.6019  1
2018 Henry RJ, Doran SJ, Barrett JP, Meadows VE, Sabirzhanov B, Stoica BA, Loane DJ, Faden AI. Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 30225790 DOI: 10.1007/s13311-018-0665-9  1
2018 Sabirzhanov B, Faden A, Aubrecht T, Henry R, Glaser E, Stoica BA. miR-711 induced down-regulation of Angiopoietin-1 mediates neuronal cell death. Journal of Neurotrauma. PMID 29774773 DOI: 10.1089/neu.2017.5572  0.84
2018 Loane DJ, Faden AI. Traumatic meningeal injury and repair mechanisms. Nature Immunology. 19: 431-432. PMID 29670238 DOI: 10.1038/s41590-018-0093-3  1
2018 Ritzel R, Doran S, Barrett J, Henry R, Ma E, Faden A, Loane DJ. Chronic Alterations in Systemic Immune Function After Traumatic Brain Injury. Journal of Neurotrauma. PMID 29421977 DOI: 10.1089/neu.2017.5399  1
2017 Ma EL, Smith AD, Desai N, Cheung L, Hanscom M, Stoica BA, Loane DJ, Shea-Donohue T, Faden AI. Bidirectional Brain-Gut Interactions and Chronic Pathological Changes after Traumatic Brain Injury in Mice. Brain, Behavior, and Immunity. PMID 28676351 DOI: 10.1016/j.bbi.2017.06.018  1
2017 Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. Journal of Neuroinflammation. 14: 65. PMID 28340575 DOI: 10.1186/s12974-017-0843-4  1
2017 Kumar A, Stoica BA, Loane DJ, Yang M, Abulwerdi G, Khan N, Kumar A, Thom SR, Faden AI. Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury. Journal of Neuroinflammation. 14: 47. PMID 28292310 DOI: 10.1186/s12974-017-0819-4  1
2017 Matyas JJ, O'Driscoll CM, Yu L, Coll-Miro M, Daugherty S, Renn CL, Faden AI, Dorsey SG, Wu J. Truncated TrkB.T1-mediated astrocyte dysfunction contributes to impaired motor function and neuropathic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28270575 DOI: 10.1523/JNEUROSCI.3353-16.2017  0.6
2016 Skovira JW, Wu J, Matyas JJ, Kumar A, Hanscom M, Kabadi SV, Fang R, Faden AI. Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury. Journal of Neuroinflammation. 13: 299. PMID 27903275 DOI: 10.1186/s12974-016-0769-2  1
2016 Kumar A, Barrett JP, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ. NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury. Brain, Behavior, and Immunity. PMID 27477920 DOI: 10.1016/j.bbi.2016.07.158  1
2016 Wu J, Zhao Z, Kumar A, Lipinski MM, Loane DJ, Stoica BA, Faden AI. ER stress and disrupted neurogenesis in the brain are associated with cognitive impairment and depressive-like behavior after spinal cord injury. Journal of Neurotrauma. PMID 27050417 DOI: 10.1089/neu.2015.4348  1
2016 Wu J, Zhao Z, Zhu X, Renn CL, Dorsey SG, Faden AI. Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury. Pain. 157: 488-503. PMID 26797506 DOI: 10.1097/j.pain.0000000000000393  0.64
2015 Skovira JW, Kabadi SV, Wu J, Zhao Z, DuBose J, Rosenthal RE, Fiskum G, Faden AI. Simulated Aeromedical Evacuation Exacerbates Experimental Brain Injury. Journal of Neurotrauma. PMID 26593382 DOI: 10.1089/neu.2015.4189  1
2015 Wu J, Sabirzhanov B, Stoica BA, Lipinski MM, Zhao Z, Zhao S, Ward N, Yang D, Faden AI. Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injury. Cell Cycle (Georgetown, Tex.). 0. PMID 26505089 DOI: 10.1080/15384101.2015.1104436  0.84
2015 Kumar A, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ. Microglial/macrophage polarization dynamics following traumatic brain injury. Journal of Neurotrauma. PMID 26486881 DOI: 10.1089/neu.2015.4268  1
2015 Sabirzhanov B, Stoica BA, Zhao Z, Loane DJ, Wu J, Dorsey SG, Faden AI. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death and Differentiation. PMID 26470728 DOI: 10.1038/cdd.2015.132  1
2015 Kabadi SV, Stoica BA, Zimmer DB, Afanador L, Duffy KB, Loane DJ, Faden AI. S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26154869 DOI: 10.1038/jcbfm.2015.165  1
2015 Faden AI, Wu J, Stoica BA, Loane DJ. Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury. British Journal of Pharmacology. PMID 25939377 DOI: 10.1111/bph.13179  1
2015 Lakkaraju SK, Mbatia H, Hanscom M, Zhao Z, Wu J, Stoica B, MacKerell AD, Faden AI, Xue F. Cyclopropyl-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5. Bioorganic & Medicinal Chemistry Letters. 25: 2275-9. PMID 25937015 DOI: 10.1016/j.bmcl.2015.04.042  1
2015 Stocchetti N, Taccone FS, Citerio G, Pepe PE, Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AI, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, et al. Neuroprotection in acute brain injury: an up-to-date review. Critical Care (London, England). 19: 186. PMID 25896893 DOI: 10.1186/s13054-015-0887-8  1
2015 Lipinski MM, Wu J, Faden AI, Sarkar C. Function and Mechanisms of Autophagy in Brain and Spinal Cord Trauma. Antioxidants & Redox Signaling. PMID 25808205 DOI: 10.1089/ars.2015.6306  1
2015 He X, Lakkaraju SK, Hanscom M, Zhao Z, Wu J, Stoica B, MacKerell AD, Faden AI, Xue F. Acyl-2-aminobenzimidazoles: a novel class of neuroprotective agents targeting mGluR5. Bioorganic & Medicinal Chemistry. 23: 2211-20. PMID 25801156 DOI: 10.1016/j.bmc.2015.02.054  1
2015 Loane DJ, Stoica BA, Faden AI. Neuroprotection for traumatic brain injury. Handbook of Clinical Neurology. 127: 343-66. PMID 25702227 DOI: 10.1016/B978-0-444-52892-6.00022-2  1
2015 Liu S, Sarkar C, Dinizo M, Faden AI, Koh EY, Lipinski MM, Wu J. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death & Disease. 6: e1582. PMID 25569099 DOI: 10.1038/cddis.2014.527  1
2015 Faden AI, Loane DJ. Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 143-50. PMID 25421001 DOI: 10.1007/s13311-014-0319-5  1
2015 Zhao Z, Sabirzhanov B, Wu J, Faden AI, Stoica BA. Voluntary Exercise Preconditioning Activates Multiple Antiapoptotic Mechanisms and Improves Neurological Recovery after Experimental Traumatic Brain Injury. Journal of Neurotrauma. PMID 25419789 DOI: 10.1089/neu.2014.3739  1
2015 Skopin MD, Kabadi SV, Viechweg SS, Mong JA, Faden AI. Chronic decrease in wakefulness and disruption of sleep-wake behavior after experimental traumatic brain injury. Journal of Neurotrauma. 32: 289-96. PMID 25242371 DOI: 10.1089/neu.2014.3664  1
2015 Kabadi SV, Stoica BA, Zimmer DB, Afanador L, Duffy KB, Loane DJ, Faden AI. S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury Journal of Cerebral Blood Flow and Metabolism. DOI: 10.1038/jcbfm.2015.165  1
2014 Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden AI, Lipinski MM. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 10: 2208-22. PMID 25484084 DOI: 10.4161/15548627.2014.981787  1
2014 Wu J, Stoica BA, Luo T, Sabirzhanov B, Zhao Z, Guanciale K, Nayar SK, Foss CA, Pomper MG, Faden AI. Isolated spinal cord contusion in rats induces chronic brain neuroinflammation, neurodegeneration, and cognitive impairment. Involvement of cell cycle activation. Cell Cycle (Georgetown, Tex.). 13: 2446-58. PMID 25483194 DOI: 10.4161/cc.29420  1
2014 Kabadi SV, Faden AI. Selective CDK inhibitors: promising candidates for future clinical traumatic brain injury trials. Neural Regeneration Research. 9: 1578-80. PMID 25368642 DOI: 10.4103/1673-5374.141779  1
2014 Wu J, Zhao Z, Sabirzhanov B, Stoica BA, Kumar A, Luo T, Skovira J, Faden AI. Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10989-1006. PMID 25122899 DOI: 10.1523/JNEUROSCI.5110-13.2014  1
2014 Loane DJ, Stoica BA, Tchantchou F, Kumar A, Barrett JP, Akintola T, Xue F, Conn PJ, Faden AI. Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 857-69. PMID 25096154 DOI: 10.1007/s13311-014-0298-6  1
2014 Sabirzhanov B, Zhao Z, Stoica BA, Loane DJ, Wu J, Borroto C, Dorsey SG, Faden AI. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10055-71. PMID 25057207 DOI: 10.1523/JNEUROSCI.1260-14.2014  1
2014 Aungst SL, Kabadi SV, Thompson SM, Stoica BA, Faden AI. Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1223-32. PMID 24756076 DOI: 10.1038/jcbfm.2014.75  1
2014 Pajoohesh-Ganji A, Burns MP, Pal-Ghosh S, Tadvalkar G, Hokenbury NG, Stepp MA, Faden AI. Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury. Brain Research. 1560: 73-82. PMID 24630972 DOI: 10.1016/j.brainres.2014.02.049  1
2014 Sun X, Rai R, Deschamps JR, Mackerell AD, Faden AI, Xue F. Boc-protected 1-(3-oxocycloalkyl)ureas via a one-step Curtius rearrangement: mechanism and scope. Tetrahedron Letters. 55: 842-844. PMID 24563555 DOI: 10.1016/j.tetlet.2013.12.021  1
2014 Stoica BA, Loane DJ, Zhao Z, Kabadi SV, Hanscom M, Byrnes KR, Faden AI. PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury. Journal of Neurotrauma. 31: 758-72. PMID 24476502 DOI: 10.1089/neu.2013.3194  1
2014 Kabadi SV, Faden AI. Neuroprotective strategies for traumatic brain injury: improving clinical translation. International Journal of Molecular Sciences. 15: 1216-36. PMID 24445258 DOI: 10.3390/ijms15011216  1
2014 Kabadi SV, Stoica BA, Loane DJ, Luo T, Faden AI. CR8, a novel inhibitor of CDK, limits microglial activation, astrocytosis, neuronal loss, and neurologic dysfunction after experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 502-13. PMID 24398934 DOI: 10.1038/jcbfm.2013.228  1
2014 Loane DJ, Kumar A, Stoica BA, Cabatbat R, Faden AI. Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation. Journal of Neuropathology and Experimental Neurology. 73: 14-29. PMID 24335533 DOI: 10.1097/NEN.0000000000000021  1
2014 Xue F, Stoica BA, Hanscom M, Kabadi SV, Faden AI. Positive allosteric modulators (PAMs) of metabotropic glutamate receptor 5 (mGluR5) attenuate microglial activation. Cns & Neurological Disorders Drug Targets. 13: 558-66. PMID 24168364 DOI: 10.2174/18715273113126660199  1
2014 Sun X, Rai R, Mackerell AD, Faden AI, Xue F. Facile one-step synthesis of 2,5-diketopiperazines Tetrahedron Letters. 55: 1905-1908. DOI: 10.1016/j.tetlet.2014.01.133  1
2014 Faden AI. Neurotherapeutics: Concept, Translation, Transition Neurotherapeutics. 11: 1. DOI: 10.1007/s13311-013-0248-8  1
2013 Luo T, Wu J, Kabadi SV, Sabirzhanov B, Guanciale K, Hanscom M, Faden J, Cardiff K, Bengson CJ, Faden AI. Propofol limits microglial activation after experimental brain trauma through inhibition of nicotinamide adenine dinucleotide phosphate oxidase. Anesthesiology. 119: 1370-88. PMID 24121215 DOI: 10.1097/ALN.0000000000000020  1
2013 Zhao Z, Faden AI, Loane DJ, Lipinski MM, Sabirzhanov B, Stoica BA. Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1897-908. PMID 23942364 DOI: 10.1038/jcbfm.2013.144  1
2013 Wu J, Renn CL, Faden AI, Dorsey SG. TrkB.T1 contributes to neuropathic pain after spinal cord injury through regulation of cell cycle pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12447-63. PMID 23884949 DOI: 10.1523/JNEUROSCI.0846-13.2013  1
2013 Wu J, Raver C, Piao C, Keller A, Faden AI. Cell cycle activation contributes to increased neuronal activity in the posterior thalamic nucleus and associated chronic hyperesthesia after rat spinal cord contusion. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 520-38. PMID 23775067 DOI: 10.1007/s13311-013-0198-1  1
2013 Lakkaraju SK, Xue F, Faden AI, MacKerell AD. Estimation of ligand efficacies of metabotropic glutamate receptors from conformational forces obtained from molecular dynamics simulations. Journal of Chemical Information and Modeling. 53: 1337-49. PMID 23688150 DOI: 10.1021/ci400160x  1
2013 Piao CS, Stoica BA, Wu J, Sabirzhanov B, Zhao Z, Cabatbat R, Loane DJ, Faden AI. Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury. Neurobiology of Disease. 54: 252-63. PMID 23313314 DOI: 10.1016/j.nbd.2012.12.017  1
2013 Kumar A, Stoica BA, Sabirzhanov B, Burns MP, Faden AI, Loane DJ. Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiology of Aging. 34: 1397-411. PMID 23273602 DOI: 10.1016/j.neurobiolaging.2012.11.013  1
2013 Loane DJ, Stoica BA, Byrnes KR, Jeong W, Faden AI. Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury. Journal of Neurotrauma. 30: 403-12. PMID 23199080 DOI: 10.1089/neu.2012.2589  1
2012 Zhao Z, Loane DJ, Murray MG, Stoica BA, Faden AI. Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury. Journal of Neurotrauma. 29: 2475-89. PMID 22924665 DOI: 10.1089/neu.2012.2511  1
2012 Sabirzhanov B, Stoica BA, Hanscom M, Piao CS, Faden AI. Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. Journal of Neurochemistry. 123: 542-54. PMID 22909049 DOI: 10.1111/j.1471-4159.2012.07927.x  1
2012 Pajoohesh-Ganji A, Knoblach SM, Faden AI, Byrnes KR. Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. Brain Research. 1475: 96-105. PMID 22884909 DOI: 10.1016/j.brainres.2012.07.058  1
2012 Wu J, Kharebava G, Piao C, Stoica BA, Dinizo M, Sabirzhanov B, Hanscom M, Guanciale K, Faden AI. Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo. Plos One. 7: e42129. PMID 22848730 DOI: 10.1371/journal.pone.0042129  1
2012 Wu J, Pajoohesh-Ganji A, Stoica BA, Dinizo M, Guanciale K, Faden AI. Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion. Journal of Neuroinflammation. 9: 169. PMID 22784881 DOI: 10.1186/1742-2094-9-169  1
2012 Loane DJ, Stoica BA, Faden AI. Metabotropic glutamate receptor-mediated signaling in neuroglia. Wiley Interdisciplinary Reviews. Membrane Transport and Signaling. 1: 136-150. PMID 22662309 DOI: 10.1002/wmts.30  1
2012 Wu J, Stoica BA, Dinizo M, Pajoohesh-Ganji A, Piao C, Faden AI. Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury. Cell Cycle (Georgetown, Tex.). 11: 1782-95. PMID 22510563 DOI: 10.4161/cc.20153  1
2012 Piao CS, Loane DJ, Stoica BA, Li S, Hanscom M, Cabatbat R, Blomgren K, Faden AI. Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury. Neurobiology of Disease. 46: 745-58. PMID 22426396 DOI: 10.1016/j.nbd.2012.03.018  1
2012 Byrnes KR, Loane DJ, Stoica BA, Zhang J, Faden AI. Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury. Journal of Neuroinflammation. 9: 43. PMID 22373400 DOI: 10.1186/1742-2094-9-43  1
2012 Kabadi SV, Stoica BA, Hanscom M, Loane DJ, Kharebava G, Murray Ii MG, Cabatbat RM, Faden AI. CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 405-21. PMID 22167461 DOI: 10.1007/s13311-011-0095-4  1
2012 Kabadi SV, Stoica BA, Loane DJ, Byrnes KR, Hanscom M, Cabatbat RM, Tan MT, Faden AI. Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury. Journal of Neurotrauma. 29: 813-27. PMID 21895533 DOI: 10.1089/neu.2011.1980  1
2012 Kabadi SV, Stoica BA, Byrnes KR, Hanscom M, Loane DJ, Faden AI. Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 137-49. PMID 21829212 DOI: 10.1038/jcbfm.2011.117  1
2011 Byrnes KR, Washington PM, Knoblach SM, Hoffman E, Faden AI. Delayed inflammatory mRNA and protein expression after spinal cord injury. Journal of Neuroinflammation. 8: 130. PMID 21975064 DOI: 10.1186/1742-2094-8-130  1
2011 Faden AI. Microglial activation and traumatic brain injury. Annals of Neurology. 70: 345-6. PMID 21905075 DOI: 10.1002/ana.22555  1
2011 Wu J, Stoica BA, Faden AI. Cell cycle activation and spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 221-8. PMID 21373950 DOI: 10.1007/s13311-011-0028-2  1
2011 Faden AI. Transitions and transformations. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 1. PMID 21274679 DOI: 10.1007/s13311-010-0023-z  1
2011 Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. Journal of Neurotrauma. 28: 225-36. PMID 21175399 DOI: 10.1089/neu.2010.1595  1
2010 Loane DJ, Faden AI. Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies. Trends in Pharmacological Sciences. 31: 596-604. PMID 21035878 DOI: 10.1016/j.tips.2010.09.005  1
2010 Cernak I, Chang T, Ahmed FA, Cruz MI, Vink R, Stoica B, Faden AI. Pathophysiological response to experimental diffuse brain trauma differs as a function of developmental age. Developmental Neuroscience. 32: 442-53. PMID 20948187 DOI: 10.1159/000320085  1
2010 Byrnes KR, Fricke ST, Faden AI. Neuropathological differences between rats and mice after spinal cord injury. Journal of Magnetic Resonance Imaging : Jmri. 32: 836-46. PMID 20882614 DOI: 10.1002/jmri.22323  1
2010 Kabadi SV, Hilton GD, Stoica BA, Zapple DN, Faden AI. Fluid-percussion-induced traumatic brain injury model in rats. Nature Protocols. 5: 1552-63. PMID 20725070 DOI: 10.1038/nprot.2010.112  1
2010 Pajoohesh-Ganji A, Byrnes KR, Fatemi G, Faden AI. A combined scoring method to assess behavioral recovery after mouse spinal cord injury. Neuroscience Research. 67: 117-25. PMID 20188770 DOI: 10.1016/j.neures.2010.02.009  1
2010 Stoica BA, Faden AI. Cell death mechanisms and modulation in traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 3-12. PMID 20129492 DOI: 10.1016/j.nurt.2009.10.023  1
2010 Faden AI, Bakshi R, Rogawski MA. Neurotherapeutics to publish primary research papers Neurotherapeutics. 7: 229. DOI: 10.1016/j.nurt.2010.05.009  1
2010 Stoica BA, Faden AI. Programmed neuronal cell death mechanisms in CNS injury Acute Neuronal Injury: the Role of Excitotoxic Programmed Cell Death Mechanisms. 169-200. DOI: 10.1007/978-0-387-73226-8_12  1
2009 Byrnes KR, Stoica B, Riccio A, Pajoohesh-Ganji A, Loane DJ, Faden AI. Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. Annals of Neurology. 66: 63-74. PMID 19670441 DOI: 10.1002/ana.21673  1
2009 Stoica BA, Byrnes KR, Faden AI. Cell cycle activation and CNS injury. Neurotoxicity Research. 16: 221-37. PMID 19526282 DOI: 10.1007/s12640-009-9050-0  1
2009 Benzinger TL, Brody D, Cardin S, Curley KC, Mintun MA, Mun SK, Wong KH, Wrathall JR. Blast-related brain injury: imaging for clinical and research applications: report of the 2008 st. Louis workshop. Journal of Neurotrauma. 26: 2127-44. PMID 19508154 DOI: 10.1089/neu.2009-0885  1
2009 Loane DJ, Stoica BA, Pajoohesh-Ganji A, Byrnes KR, Faden AI. Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase. The Journal of Biological Chemistry. 284: 15629-39. PMID 19364772 DOI: 10.1074/jbc.M806139200  1
2009 Loane DJ, Pocivavsek A, Moussa CE, Thompson R, Matsuoka Y, Faden AI, Rebeck GW, Burns MP. Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nature Medicine. 15: 377-9. PMID 19287391 DOI: 10.1038/nm.1940  1
2009 Byrnes KR, Loane DJ, Faden AI. Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 94-107. PMID 19110202 DOI: 10.1016/j.nurt.2008.10.038  1
2009 Stoica B, Byrnes K, Faden AI. Multifunctional drug treatment in neurotrauma. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 14-27. PMID 19110196 DOI: 10.1016/j.nurt.2008.10.029  1
2009 Byrnes KR, Stoica B, Loane DJ, Riccio A, Davis MI, Faden AI. Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity. Glia. 57: 550-60. PMID 18816644 DOI: 10.1002/glia.20783  1
2008 Cartagena CM, Ahmed F, Burns MP, Pajoohesh-Ganji A, Pak DT, Faden AI, Rebeck GW. Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain. Journal of Neurotrauma. 25: 1087-98. PMID 18729719 DOI: 10.1089/neu.2007.0444  1
2008 Hilton GD, Stoica BA, Byrnes KR, Faden AI. Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1845-59. PMID 18612315 DOI: 10.1038/jcbfm.2008.75  1
2007 Byrnes KR, Stoica BA, Fricke S, Di Giovanni S, Faden AI. Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury. Brain : a Journal of Neurology. 130: 2977-92. PMID 17690131 DOI: 10.1093/brain/awm179  1
2007 Faden AI, Stoica B. Neuroprotection: challenges and opportunities. Archives of Neurology. 64: 794-800. PMID 17562927 DOI: 10.1001/archneur.64.6.794  1
2007 Byrnes KR, Faden AI. Role of cell cycle proteins in CNS injury. Neurochemical Research. 32: 1799-807. PMID 17404835 DOI: 10.1007/s11064-007-9312-2  1
2007 Faden AI. It's Official: NeuroRx is Now Neurotherapeutics Neurotherapeutics. 4: 1. DOI: 10.1016/j.nurt.2006.10.006  1
2006 Faden AI. Changing the name of the journal. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 417. PMID 17012053 DOI: 10.1016/j.nurx.2006.08.002  1
2006 Lea PM, Faden AI. Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. Cns Drug Reviews. 12: 149-66. PMID 16958988 DOI: 10.1111/j.1527-3458.2006.00149.x  1
2006 Di Giovanni S, Knights CD, Rao M, Yakovlev A, Beers J, Catania J, Avantaggiati ML, Faden AI. The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration. The Embo Journal. 25: 4084-96. PMID 16946709 DOI: 10.1038/sj.emboj.7601292  1
2006 Movsesyan VA, Faden AI. Neuroprotective effects of selective group II mGluR activation in brain trauma and traumatic neuronal injury. Journal of Neurotrauma. 23: 117-27. PMID 16503796 DOI: 10.1089/neu.2006.23.117  1
2006 Byrnes KR, Garay J, Di Giovanni S, De Biase A, Knoblach SM, Hoffman EP, Movsesyan V, Faden AI. Expression of two temporally distinct microglia-related gene clusters after spinal cord injury. Glia. 53: 420-33. PMID 16345062 DOI: 10.1002/glia.20295  1
2005 Faden AI, Movsesyan VA, Fang X, Wang S. Identification of novel neuroprotective agents using pharmacophore modeling. Chemistry & Biodiversity. 2: 1564-70. PMID 17191955 DOI: 10.1002/cbdv.200590127  1
2005 Faden AI, Knoblach SM, Movsesyan VA, Lea PM, Cernak I. Novel neuroprotective tripeptides and dipeptides. Annals of the New York Academy of Sciences. 1053: 472-81. PMID 16179555 DOI: 10.1196/annals.1344.041  1
2005 Cernak I, Stoica B, Byrnes KR, Di Giovanni S, Faden AI. Role of the cell cycle in the pathobiology of central nervous system trauma. Cell Cycle (Georgetown, Tex.). 4: 1286-93. PMID 16082214  1
2005 De Biase A, Knoblach SM, Di Giovanni S, Fan C, Molon A, Hoffman EP, Faden AI. Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. Physiological Genomics. 22: 368-81. PMID 15942019 DOI: 10.1152/physiolgenomics.00081.2005  1
2005 Di Giovanni S, Movsesyan V, Ahmed F, Cernak I, Schinelli S, Stoica B, Faden AI. Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury. Proceedings of the National Academy of Sciences of the United States of America. 102: 8333-8. PMID 15923260 DOI: 10.1073/pnas.0500989102  1
2005 Faden AI, Movsesyan VA, Knoblach SM, Ahmed F, Cernak I. Neuroprotective effects of novel small peptides in vitro and after brain injury. Neuropharmacology. 49: 410-24. PMID 15907950 DOI: 10.1016/j.neuropharm.2005.04.001  1
2005 Stoica BA, Movsesyan VA, Knoblach SM, Faden AI. Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. Molecular and Cellular Neurosciences. 29: 355-71. PMID 15905098 DOI: 10.1016/j.mcn.2005.02.009  1
2005 Lea PM, Movsesyan VA, Faden AI. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors. British Journal of Pharmacology. 145: 527-34. PMID 15821750 DOI: 10.1038/sj.bjp.0706219  1
2005 Knoblach SM, Huang X, VanGelderen J, Calva-Cerqueira D, Faden AI. Selective caspase activation may contribute to neurological dysfunction after experimental spinal cord trauma. Journal of Neuroscience Research. 80: 369-80. PMID 15795935 DOI: 10.1002/jnr.20465  1
2005 Di Giovanni S, Faden AI, Yakovlev A, Duke-Cohan JS, Finn T, Thouin M, Knoblach S, De Biase A, Bregman BS, Hoffman EP. Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 153-4. PMID 15522907 DOI: 10.1096/fj.04-2694fje  1
2005 Di Giovanni S, De Biase A, Yakovlev A, Finn T, Beers J, Hoffman EP, Faden AI. In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury. The Journal of Biological Chemistry. 280: 2084-91. PMID 15522871 DOI: 10.1074/jbc.M411975200  1
2005 Hoke A, Lazarovici P, Youdim M, Banik N, Faden A, Doré S, Marcheselli V, Oxenkrug G, Mandel S, Virmani A. Questions and answers: Session X: Novel approaches to neuroprotection Annals of the New York Academy of Sciences. 1053: 502-504. DOI: 10.1196/annals.1344.069  1
2005 Banik N, Slikker W, Sharma H, Qi X, Lazarovici P, Chuang DM, Mocchetti I, Kuan CY, Skaper S, Marini A, Imam S, Doré S, Yenari M, Fiskum G, Ruzdijic S, ... ... Faden A, et al. Questions and answers: Session II: Mechanisms of neuroprotection (1) Annals of the New York Academy of Sciences. 1053: 99-106. DOI: 10.1196/annals.1344.061  1
2005 Cernak I, Lea PM, Faden AI. Neurotrauma Neuroprotection: Models, Mechanisms and Therapies. 95-127. DOI: 10.1002/3527603867.ch6  1
2004 Yakovlev AG, Faden AI. Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 5-16. PMID 15717003 DOI: 10.1602/neurorx.1.1.5  1
2004 Faden AI, Knoblach SM, Movsesyan VA, Cernak I. Novel small peptides with neuroprotective and nootropic properties. Journal of Alzheimer's Disease : Jad. 6: S93-7. PMID 15665420  1
2004 Knoblach SM, Alroy DA, Nikolaeva M, Cernak I, Stoica BA, Faden AI. Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 1119-32. PMID 15529012 DOI: 10.1097/01.WCB.0000138664.17682.32  1
2004 Movsesyan VA, Stoica BA, Yakovlev AG, Knoblach SM, Lea PM, Cernak I, Vink R, Faden AI. Anandamide-induced cell death in primary neuronal cultures: role of calpain and caspase pathways. Cell Death and Differentiation. 11: 1121-32. PMID 15375383 DOI: 10.1038/sj.cdd.4401442  1
2004 Cernak I, Vink R, Zapple DN, Cruz MI, Ahmed F, Chang T, Fricke ST, Faden AI. The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats. Neurobiology of Disease. 17: 29-43. PMID 15350963 DOI: 10.1016/j.nbd.2004.05.011  1
2004 Movsesyan VA, Stoica BA, Faden AI. MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor. Journal of Neurochemistry. 89: 1528-36. PMID 15189356 DOI: 10.1111/j.1471-4159.2004.02451.x  1
2004 Cernak I, Vink R, Natale J, Stoica B, Lea PM, Movsesyan V, Ahmed F, Knoblach SM, Fricke ST, Faden AI. The "dark side" of endocannabinoids: a neurotoxic role for anandamide. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 564-78. PMID 15129189 DOI: 10.1097/00004647-200405000-00011  1
2004 Fricke ST, Vink R, Chiodo C, Cernak I, Ileva L, Faden AI. Consistent and reproducible slice selection in rodent brain using a novel stereotaxic device for MRI. Journal of Neuroscience Methods. 136: 99-102. PMID 15126050 DOI: 10.1016/j.jneumeth.2004.01.003  1
2004 Yakovlev AG, Di Giovanni S, Wang G, Liu W, Stoica B, Faden AI. BOK and NOXA are essential mediators of p53-dependent apoptosis. The Journal of Biological Chemistry. 279: 28367-74. PMID 15102863 DOI: 10.1074/jbc.M313526200  1
2004 Faden AI. NeuroRx®: A New Journal Focusing on Critical Reviews Relating to Neurotherapeutics Neurorx. 1: 1-2. DOI: 10.1602/neurorx.1.1.1  1
2003 Lea PM, Faden AI. Modulation of metabotropic glutamate receptors as potential treatment for acute and chronic neurodegenerative disorders. Drug News & Perspectives. 16: 513-22. PMID 14668949 DOI: 10.1358/dnp.2003.16.8.829350  1
2003 Lea PM, Custer SJ, Stoica BA, Faden AI. Modulation of stretch-induced enhancement of neuronal NMDA receptor current by mGluR1 depends upon presence of glia. Journal of Neurotrauma. 20: 1233-49. PMID 14651810 DOI: 10.1089/089771503770802907  1
2003 Natale JE, Ahmed F, Cernak I, Stoica B, Faden AI. Gene expression profile changes are commonly modulated across models and species after traumatic brain injury. Journal of Neurotrauma. 20: 907-27. PMID 14588109 DOI: 10.1089/089771503770195777  1
2003 Stoica BA, Movsesyan VA, Lea PM, Faden AI. Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. Molecular and Cellular Neurosciences. 22: 365-82. PMID 12691738 DOI: 10.1016/S1044-7431(02)00028-3  1
2003 Di Giovanni S, Knoblach SM, Brandoli C, Aden SA, Hoffman EP, Faden AI. Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Annals of Neurology. 53: 454-68. PMID 12666113 DOI: 10.1002/ana.10472  1
2003 Faden AI, Fox GB, Di X, Knoblach SM, Cernak I, Mullins P, Nikolaeva M, Kozikowski AP. Neuroprotective and nootropic actions of a novel cyclized dipeptide after controlled cortical impact injury in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 355-63. PMID 12621310  1
2003 Faden AI, Knoblach SM, Cernak I, Fan L, Vink R, Araldi GL, Fricke ST, Roth BL, Kozikowski AP. Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 342-54. PMID 12621309  1
2002 Knoblach SM, Faden AI. Administration of either anti-intercellular adhesion molecule-1 or a nonspecific control antibody improves recovery after traumatic brain injury in the rat. Journal of Neurotrauma. 19: 1039-50. PMID 12482117 DOI: 10.1089/089771502760341956  1
2002 Faden AI. Neuroprotection and traumatic brain injury: theoretical option or realistic proposition. Current Opinion in Neurology. 15: 707-12. PMID 12447109 DOI: 10.1097/01.wco.0000044767.39452.bf  1
2002 Movsesyan VA, Yakovlev AG, Dabaghyan EA, Stoica BA, Faden AI. Ceramide induces neuronal apoptosis through the caspase-9/caspase-3 pathway. Biochemical and Biophysical Research Communications. 299: 201-7. PMID 12437970 DOI: 10.1016/S0006-291X(02)02593-7  1
2002 Knoblach SM, Nikolaeva M, Huang X, Fan L, Krajewski S, Reed JC, Faden AI. Multiple caspases are activated after traumatic brain injury: evidence for involvement in functional outcome. Journal of Neurotrauma. 19: 1155-70. PMID 12427325 DOI: 10.1089/08977150260337967  1
2002 Toman RE, Movsesyan V, Murthy SK, Milstien S, Spiegel S, Faden AI. Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis. Journal of Neuroscience Research. 68: 323-30. PMID 12111862 DOI: 10.1002/jnr.10190  1
2002 Prakash KR, Tang Y, Kozikowski AP, Flippen-Anderson JL, Knoblach SM, Faden AI. Synthesis and biological activity of novel neuroprotective diketopiperazines. Bioorganic & Medicinal Chemistry. 10: 3043-8. PMID 12110327 DOI: 10.1016/S0968-0896(02)00132-3  1
2001 Yakovlev AG, Faden AI. Caspase-dependent apoptotic pathways in CNS injury. Molecular Neurobiology. 24: 131-44. PMID 11831549 DOI: 10.1385/MN:24:1-3:131  1
2001 Lea PM, Faden AI. Traumatic brain injury: developmental differences in glutamate receptor response and the impact on treatment. Mental Retardation and Developmental Disabilities Research Reviews. 7: 235-48. PMID 11754517 DOI: 10.1002/mrdd.1033  1
2001 Bao WL, Williams AJ, Faden AI, Tortella FC. Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia. Brain Research. 922: 173-9. PMID 11743947 DOI: 10.1016/S0006-8993(01)03062-1  1
2001 Faden AI. Neuroprotection and traumatic brain injury: the search continues. Archives of Neurology. 58: 1553-5. PMID 11594912  1
2001 Yakovlev AG, Ota K, Wang G, Movsesyan V, Bao WL, Yoshihara K, Faden AI. Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7439-46. PMID 11567033  1
2001 Vink R, Mullins PG, Temple MD, Bao W, Faden AI. Small shifts in craniotomy position in the lateral fluid percussion injury model are associated with differential lesion development. Journal of Neurotrauma. 18: 839-47. PMID 11526990 DOI: 10.1089/089771501316919201  1
2001 Yakovlev AG, Di X, Movsesyan V, Mullins PG, Wang G, Boulares H, Zhang J, Xu M, Faden AI. Presence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury. Molecular Medicine (Cambridge, Mass.). 7: 205-16. PMID 11471558  1
2001 Allen JW, Eldadah BA, Huang X, Knoblach SM, Faden AI. Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. Journal of Neuroscience Research. 65: 45-53. PMID 11433428 DOI: 10.1002/jnr.1126  1
2001 Allen JW, Vicini S, Faden AI. Exacerbation of neuronal cell death by activation of group I metabotropic glutamate receptors: role of NMDA receptors and arachidonic acid release. Experimental Neurology. 169: 449-60. PMID 11358458 DOI: 10.1006/exnr.2001.7672  1
2001 Faden AI, O'Leary DM, Fan L, Bao W, Mullins PG, Movsesyan VA. Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma. Experimental Neurology. 167: 435-44. PMID 11161632 DOI: 10.1006/exnr.2000.7577  1
2001 Movsesyan VA, Yakovlev AG, Fan L, Faden AI. Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis Experimental Neurology. 167: 366-375. PMID 11161625 DOI: 10.1006/exnr.2000.7567  1
2001 Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. The Journal of Pharmacology and Experimental Therapeutics. 296: 41-7. PMID 11123360  1
2000 O'Leary DM, Movsesyan V, Vicini S, Faden AI. Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. British Journal of Pharmacology. 131: 1429-37. PMID 11090117 DOI: 10.1038/sj.bjp.0703715  1
2000 Toman RE, Spiegel S, Faden AI. Role of ceramide in neuronal cell death and differentiation. Journal of Neurotrauma. 17: 891-8. PMID 11063055  1
2000 Eldadah BA, Faden AI. Caspase pathways, neuronal apoptosis, and CNS injury Journal of Neurotrauma. 17: 811-829. PMID 11063050  1
2000 Knoblach SM, Faden AI. Cortical interleukin-1β elevation after traumatic brain injury in the rat: No effect of two selective antagonists on motor recovery Neuroscience Letters. 289: 5-8. PMID 10899395 DOI: 10.1016/S0304-3940(00)01263-5  1
2000 Allen JW, Knoblach SM, Faden AI. Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro Cell Death and Differentiation. 7: 470-476. PMID 10800080  1
2000 Albensi BC, Knoblach SM, Chew BGM, O'Reilly MP, Faden AI, Pekar JJ. Diffusion and high resolution MRI of traumatic brain injury in rats: Time course and correlation with histology Experimental Neurology. 162: 61-72. PMID 10716889 DOI: 10.1006/exnr.2000.7256  1
2000 Eldadah BA, Ren RF, Faden AI. Ribozyme-mediated inhibition of caspase-3 protects, cerebellar granule cells, from apoptosis induced by serum-potassium deprivation Journal of Neuroscience. 20: 179-186. PMID 10627595  1
2000 Faden AI. Introduction: Apoptosis and CNS injury Journal of Neurotrauma. 17: 799.  1
1999 Faden AI, Fox G, Fan L, Knoblach S, Araldi GL, Kozikowski AP. Neuroprotective and cognitive enhancing effects of novel small peptides Annals of the New York Academy of Sciences. 890: 120. PMID 10668419  1
1999 Faden AI, Fox GB, Fan L, Araldi GL, Qiao L, Wang S, Kozikowski AP. Novel TRH analog improves motor and cognitive recovery after traumatic brain injury in rodents American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 277: R1196-R1204. PMID 10516262  1
1999 Allen JW, Knoblach SM, Faden AI. Combined mechanical trauma and metabolic impairment in vitro induces NMDA receptor-dependent neuronal cell death and caspase-3-dependent apoptosis Faseb Journal. 13: 1875-1882. PMID 10506592  1
1999 Allen JW, Eldadah BA, Faden AI. β-Amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: Exacerbation by selective inhibition of group I metabotropic glutamate receptors Neuropharmacology. 38: 1243-1252. PMID 10462136 DOI: 10.1016/S0028-3908(99)00044-1  1
1999 Allen JW, Ivanova SA, Fan L, Espey MG, Basile AS, Faden AI. Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. The Journal of Pharmacology and Experimental Therapeutics. 290: 112-20. PMID 10381766  1
1999 Fox GB, Levasseur RA, Faden AI. Behavioral responses of C57BL/6, FVB/N, and 129/SvEMS mouse strains to traumatic brain injury: Implications for gene targeting approaches to neurotrauma Journal of Neurotrauma. 16: 377-389. PMID 10369558  1
1999 Fan L, Yakovlev AG, Faden AI. Site-specific cleavage of 28S rRNA as a marker of traumatic brain injury Journal of Neurotrauma. 16: 357-364. PMID 10369556  1
1999 Knoblach SM, Fan L, Faden AI. Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment Journal of Neuroimmunology. 95: 115-125. PMID 10229121 DOI: 10.1016/S0165-5728(98)00273-2  1
1998 Fox GB, Fan L, Levasseur RA, Faden AI. Effect of traumatic brain injury on mouse spatial and nonspatial learning in the Barnes circular maze Journal of Neurotrauma. 15: 1037-1046. PMID 9872460  1
1998 Fox GB, Faden AI. Traumatic brain injury causes delayed motor and cognitive impairment in a mutant mouse strain known to exhibit delayed Wallerian degeneration Journal of Neuroscience Research. 53: 718-727. PMID 9753199 DOI: 10.1002/(SICI)1097-4547(19980915)53:6<718::AID-JNR9>3.0.CO;2-8  1
1998 Knoblach SM, Faden AI. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury Experimental Neurology. 153: 143-151. PMID 9743576 DOI: 10.1006/exnr.1998.6877  1
1998 Fox GB, Fan L, Levasseur RA, Faden AI. Sustained sensory/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouse Journal of Neurotrauma. 15: 599-614. PMID 9726259  1
1998 Mukhin AG, Ivanova SA, Allen JW, Faden AI. Mechanical injury to neuronal/glial cultures in microplates: Role of NMDA receptors and pH in secondary neuronal cell death Journal of Neuroscience Research. 51: 748-758. PMID 9545088 DOI: 10.1002/(SICI)1097-4547(19980315)51:6<748::AID-JNR8>3.0.CO;2-B  1
1998 Faden AI. Iatrogenic illness: An overview with particular reference to neurologic complications Neurologic Clinics. 16: 1-8. PMID 9421537 DOI: 10.1016/S0733-8619(05)70363-7  1
1997 Faden AI, Ivanova SA, Yakovlev AG, Mukhin AG. Neuroprotective effects of group III mGluR in traumatic neuronal injury Journal of Neurotrauma. 14: 885-895. PMID 9475370  1
1997 Beattie MS, Bresnahan JC, Komon J, Tovar CA, Van Meter M, Anderson DK, Faden AI, Hsu CY, Noble LJ, Salzman S, Young W. Endogenous repair after spinal cord contusion injuries in the rat. Experimental Neurology. 148: 453-63. PMID 9417825 DOI: 10.1006/exnr.1997.6695  1
1997 Mukhin AG, Ivanova SA, Knoblach SM, Faden AI. New in vitro model of traumatic neuronal injury: Evaluation of secondary injury and glutamate receptor-mediated neurotoxicity Journal of Neurotrauma. 14: 651-663. PMID 9337127  1
1997 Yakovlev AG, Knoblach SM, Fan L, Fox GB, Goodnight R, Faden AI. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury Journal of Neuroscience. 17: 7415-7424. PMID 9295387  1
1997 Mukhin AG, Ivanova SA, Faden AI. mGluR modulation of post-traumatic neuronal death: Role of NMDA receptors Neuroreport. 8: 2561-2566. PMID 9261827  1
1997 Eldadah BA, Yakovlev AG, Faden AI. The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells Journal of Neuroscience. 17: 6105-6113. PMID 9236222  1
1997 Faden AI. Therapeutic approaches to spinal cord injury Advances in Neurology. 72: 377-386. PMID 8993713  1
1996 Eldadah BA, Yakovlev AG, Faden AI. A new approach for the electrophoretic detection of apoptosis Nucleic Acids Research. 24: 4092-4093. PMID 8918817 DOI: 10.1093/nar/24.20.4092  1
1996 Basso DM, Beattie MS, Bresnahan JC, Anderson DK, Faden AI, Gruner JA, Holford TR, Hsu CY, Noble LJ, Nockels R, Perot PL, Salzman SK, Young W. MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study. Journal of Neurotrauma. 13: 343-59. PMID 8863191  1
1996 Mukhin A, Fan L, Faden AI. Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury Journal of Neuroscience. 16: 6012-6020. PMID 8815884  1
1996 Faden AI. Neurotoxic versus neuroprotective actions of endogenous opioid peptides: implications for treatment of CNS injury Nida Research Monograph. 163: 318-330. PMID 8809866  1
1996 Faden AI. Pharmacologic treatment of acute traumatic brain injury Journal of the American Medical Association. 276: 569-570. PMID 8709409 DOI: 10.1001/jama.276.7.569  1
1996 Faden AI. Pharmacological treatment of central nervous system trauma Pharmacology and Toxicology. 78: 12-17. PMID 8685080  1
1996 Sharpe VA, Faden AI. Appropriateness in Patient Care: A New Conceptual Framework Milbank Quarterly. 74: 115-138. PMID 8596518  1
1995 Sappey-Marinier D, Chileuitt L, Weiner MW, Faden AI, Weinstein PR. Hypoglycemia prevents increase in lactic acidosis during reperfusion after temporary cerebral ischemia in rats Nmr in Biomedicine. 8: 171-178. PMID 8771092  1
1995 Sun FY, Faden AI. Pretreatment with antisense oligodeoxynucleotides directed against the NMDA-R1 receptor enhances survival and behavioral recovery following traumatic brain injury in rats Brain Research. 693: 163-168. PMID 8653404 DOI: 10.1016/0006-8993(95)00731-5  1
1995 Yakovlev AG, Faden AI. Molecular biology of CNS injury Journal of Neurotrauma. 12: 767-777. PMID 8594206  1
1995 Yakovlev AG, Krueger KE, Faden AI. Structure and expression of a rat κ opioid receptor gene Journal of Biological Chemistry. 270: 6421-6424. PMID 7896774 DOI: 10.1074/jbc.270.12.6421  1
1995 Sun FY, Faden AI. Neuroprotective effects of 619C89, a use-dependent sodium channel blocker, in rat traumatic brain injury Brain Research. 673: 133-140. PMID 7757466 DOI: 10.1016/0006-8993(94)01413-C  1
1995 Yamakami I, Vink R, Faden AI, Gennarelli TA, Lenkinski R, McIntosh TK. Effects of acute ethanol intoxication on experimental brain injury in the rat: neurobehavioral and phosphorus-31 nuclear magnetic resonance spectroscopy studies. Journal of Neurosurgery. 82: 813-21. PMID 7714607 DOI: 10.3171/jns.1995.82.5.0813  1
1995 Headrick JP, Faden AI, Vink R. Intrathecal dynorphin-A infusion in rat spinal cord causes energy depletion, edema and neurologic dysfunction Neurochemistry International. 26: 489-495. PMID 7492946 DOI: 10.1016/0197-0186(94)00153-L  1
1995 Pitts LH, Ross A, Chase GA, Faden AI. Treatment with thyrotropin-releasing hormone (TRH) in patients with traumatic spinal cord injuries Journal of Neurotrauma. 12: 235-243. PMID 7473798  1
1994 Headrick JP, Bendall MR, Faden AI, Vink R. Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: Potential role in secondary injury Journal of Cerebral Blood Flow and Metabolism. 14: 853-861. PMID 8063880  1
1994 Faden AI, Sharpe VA. Iatrogenic Neurological Complications Archives of Neurology. 51: 1184-1185. PMID 7986171 DOI: 10.1001/archneur.1994.00540240028011  1
1994 Sun FY, Faden AI. High- and low-affinity NMDA receptor-binding sites in rat spinal cord: effects of traumatic injury Brain Research. 666: 88-92. PMID 7889371 DOI: 10.1016/0006-8993(94)90285-2  1
1994 Sun FY, Faden AI. N-Methyl-d-aspartate receptors mediate post-traumatic increases of protein kinase C in rat brain Brain Research. 661: 63-69. PMID 7834386 DOI: 10.1016/0006-8993(94)91181-9  1
1994 Yakovlev AG, Faden AI. Sequential expression of c-fos protooncogene, TNF-alpha, and dynorphin genes in spinal cord following experimental traumatic injury Molecular and Chemical Neuropathology. 23: 179-190. PMID 7702707 DOI: 10.1007/BF02815410  1
1994 McIntosh TK, Fernyak S, Yamakami I, Faden AI. Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats Am.J.Physiol.. 267: R665-R672.  1
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