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Melvin V. Simpson - Publications

Affiliations: 
1967 Biochemistry Dartmouth University, Hanover, NH, United States 
 1967- Biochemistry Stony Brook University, Stony Brook, NY, United States 
Area:
Mitochondrial DNA and its replication; conformational changes in ribosomes related to function; biochemistry of memory, using split brain systems.
Website:
https://www.stonybrook.edu/commcms/biochem/about-us/history.php
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1997 Keilbaugh SA, Hobbs GA, Simpson MV. Effect of 2',3'-dideoxycytidine on oxidative phosphorylation in the PC12 cell, a neuronal model. Biochemical Pharmacology. 53: 1485-92. PMID 9260876 DOI: 10.1016/S0006-2952(97)82442-2  0.457
1995 Hobbs GA, Keilbaugh SA, Rief PM, Simpson MV. Cellular targets of 3'-azido-3'-deoxythymidine: an early (non-delayed) effect on oxidative phosphorylation. Biochemical Pharmacology. 50: 381-90. PMID 7646539 DOI: 10.1016/0006-2952(95)00141-L  0.456
1995 Ghazala S, Ramaswamy H, Smith J, Simpson M. Thermal process simulations for sous vide processing of fish and meat foods Food Research International. 28: 117-122. DOI: 10.1016/0963-9969(95)90794-B  0.171
1994 Barile M, Valenti D, Hobbs GA, Abruzzese MF, Keilbaugh SA, Passarella S, Quagliariello E, Simpson MV. Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase. Biochemical Pharmacology. 48: 1405-12. PMID 7945440 DOI: 10.1016/0006-2952(94)90564-9  0.419
1993 Keilbaugh SA, Hobbs GA, Simpson MV. Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate. Molecular Pharmacology. 44: 702-6. PMID 8232219  0.325
1992 Hobbs GA, Keilbaugh SA, Simpson MV. The Friend murine erythroleukemia cell, a model system for studying the association between bone marrow toxicity induced by 3'-azido-3'-dideoxythymidine and dideoxynucleoside inhibition of mtDNA replication. Biochemical Pharmacology. 43: 1397-1400. PMID 1567464 DOI: 10.1016/0006-2952(92)90194-N  0.347
1992 Phillip LE, Simpson MV. Differentiation of the effects of protein status and acid-base balance on the appetite of sheep for lucerne silage The Journal of Agricultural Science. 118: 249-257. DOI: 10.1017/S0021859600068866  0.228
1991 Keilbaugh SA, Prusoff WH, Simpson MV. The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs Biochemical Pharmacology. 42: R5-R8. PMID 1648918 DOI: 10.1016/0006-2952(91)90672-R  0.461
1991 Simpson M, Smith J, Ramaswamy H, Simpson B, Ghazala S. Thermal Kinetic Studies of Streptococcus Faecium in Minimally Processed Sous Vide Products Canadian Institute of Food Science and Technology Journal. 24: 193. DOI: 10.1016/S0315-5463(91)70098-9  0.186
1990 SIMPSON B, SIMPSON M, Haard N. Properties of Trypsin from the Pyloric Ceca of Atlantic Cod (Gadus morhua) Journal of Food Science. 55: 959-961. DOI: 10.1111/j.1365-2621.1990.tb01574.x  0.188
1989 Simpson MV, Chin CD, Keilbaugh SA, Lin Ts, Prusoff WH. Studies on the inhibition of mitochondrial DNA replication by 3′-azido-3′-dhoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication Biochemical Pharmacology. 38: 1033-1036. PMID 2706007 DOI: 10.1016/0006-2952(89)90245-1  0.465
1987 Poccia DL, Simpson MV, Green GR. Transitions in histone variants during sea urchin spermatogenesis Developmental Biology. 121: 445-453. PMID 3582736 DOI: 10.1016/0012-1606(87)90181-3  0.237
1987 Simpson MV, Poccia D. Sea urchin testicular cells evaluated by fluorescence microscopy of unfixed tissue. Gamete Research. 17: 131-44. PMID 3507343 DOI: 10.1002/mrd.1120170205  0.254
1987 Mohraz M, Simpson MV, Smith PR. The three-dimensional structure of the Na,K-ATPase from electron microscopy. The Journal of Cell Biology. 105: 1-8. PMID 3038922  0.187
1986 Hanas JS, Simpson MV. Fluorescence studies on a streptomycin-induced conformational change in ribosomes which correlates with misreading. The Journal of Biological Chemistry. 261: 6670-6. PMID 3516997  0.305
1986 Gallagher M, Weinberg R, Simpson MV. Effect of the bacterial DNA gyrase inhibitors, novobiocin, nalidixic acid, and oxolinic acid, on oxidative phosphorylation. The Journal of Biological Chemistry. 261: 8604-7. PMID 3013857  0.369
1985 Hanas JS, Simpson MV. Modification of Escherichia coli ribosomes with the fluorescent reagent N-[[(iodoacetyl)amino]ethyl]-5-naphthylamine-1-sulfonic acid. Identification of derivatized L31' and studies on its intraribosomal properties. Biochemistry. 24: 7303-9. PMID 3910100  0.302
1985 Fairfield FR, Bauer WR, Simpson MV. Studies on mitochondrial type I topoisomerase and on its function. Biochimica Et Biophysica Acta. 824: 45-57. PMID 2981552 DOI: 10.1016/0167-4781(85)90028-4  0.495
1984 MOHRAZ M, RINDER CA, SIMPSON MV, SMITH PR. The Structure of (Na+,K+)-ATPase as Revealed by Electron Microscopy Annals of the New York Academy of Sciences. 435: 561-563. DOI: 10.1111/j.1749-6632.1984.tb13883.x  0.187
1983 Castora FJ, Vissering FF, Simpson MV. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria Bba - Gene Structure and Expression. 740: 417-427. PMID 6309236 DOI: 10.1016/0167-4781(83)90090-8  0.718
1982 Brown GG, Simpson MV. Novel features of animal mtDNA evolution as shown by sequences of two rat cytochrome oxidase subunit II genes. Proceedings of the National Academy of Sciences of the United States of America. 79: 3246-50. PMID 6285344  0.339
1982 Castora FJ, Sternglanz R, Simpson MV. A New Mitochondrial Topoisomerase from Rat Liver That Catenates DNA Cold Spring Harbor Monograph Archive. 12: 143-154. DOI: 10.1101/087969145.12.143  0.701
1981 Brown GG, Castora FJ, Frantz SC, Simpson MV. Mitochondrial DNA polymorphism: evolutionary studies of the genus Rattus. Annals of the New York Academy of Sciences. 361: 135-53. PMID 6941716 DOI: 10.1111/J.1749-6632.1981.Tb54362.X  0.679
1981 Brown GG, Simpson MV. Intra- and interspecific variation of the mitochondrial genome in Rattus norvegicus and Rattus rattus: restriction enzyme analysis of variant mitochondrial DNA molecules and their evolutionary relationships. Genetics. 97: 125-43. PMID 6266911  0.336
1980 Deutsch DG, Schechter N, Brecha N, Quitschke W, Schulman P, Cane M, Gazzaniga MS, Simpson MV. Analysis of protein levels and synthesis after learning in the split-brain pigeon. Brain Research. 198: 135-45. PMID 7407580 DOI: 10.1016/0006-8993(80)90349-2  0.258
1980 Castora FJ, Arnheim N, Simpson MV. Mitochondrial DNA polymorphism: evidence that variants detected by restriction enzymes differ in nucleotide sequence rather than in methylation Proceedings of the National Academy of Sciences of the United States of America. 77: 6415-6419. PMID 6256736  0.649
1979 Francisco JF, Brown GG, Simpson MV. Further studies on types A and B rat mtDNAs: cleavage maps and evidence for cytoplasmic inheritance in mammals. Plasmid. 2: 426-36. PMID 482430  0.253
1979 Castora FJ, Simpson MV. Search for a DNA gyrase in mammalian mitochondria Journal of Biological Chemistry. 254: 11193-11195. PMID 227861  0.694
1979 Fairfield FR, Bauer WR, Simpson MV. Mitochondria contain a distinct DNA topoisomerase. The Journal of Biological Chemistry. 254: 9352-4. PMID 226516  0.436
1977 Francisco JF, Simpson MV. The occurrence of two types of mitochondrial DNA in rat populations as detected by EcoRI endonuclease analysis. Febs Letters. 79: 290-4. PMID 891943 DOI: 10.1016/0014-5793(77)80805-3  0.476
1977 Van Tuyle GC, Hamilton FD, Vissering FF, Simpson MV. Biosynthesis of mitochondrial DNA. Is 8 S DNA an artifact? The Journal of Biological Chemistry. 252: 2984-91. PMID 856809  0.42
1974 Simpson MV. Hydrogen-tritium exchange studies on ribosomes. Methods in Enzymology. 30: 395-406. PMID 4852319 DOI: 10.1016/0076-6879(74)30041-9  0.217
1973 Parsons P, Simpson MV. Deoxyribonucleic acid biosynthesis in mitochondria. Studies on the incorporation of labeled precursors into mitochondrial deoxyribonucleic acid. The Journal of Biological Chemistry. 248: 1912-9. PMID 4690581  0.344
1971 Chuang DM, Silberstein HA, Simpson MV. The role of ribosomal conformation in protein synthesis: conformational changes in the ribosome during the tranlocation step. Archives of Biochemistry and Biophysics. 144: 778-80. PMID 4936516 DOI: 10.1016/0003-9861(71)90388-2  0.385
1971 Chuang D, Simpson MV. A translocation-associated ribosomal conformational change detected by hydrogen exchange and sedimentation velocity. Proceedings of the National Academy of Sciences of the United States of America. 68: 1474-8. PMID 4934519 DOI: 10.1073/Pnas.68.7.1474  0.372
1970 Meyer RR, Simpson MV. Deoxyribonucleic acid biosynthesis in mitochondria. Purification and general properties of rat liver mitochondrial deoxyribonucleic acid polymerase. The Journal of Biological Chemistry. 245: 3426-35. PMID 4918151  0.373
1969 Meyer RR, Simpson MV. DNA biosynthesis in mitochondria. Differential inhibition of mitochondrial and nuclear DNA polymerases by the mutagenic dyes ethidium bromide and acriflavin. Biochemical and Biophysical Research Communications. 34: 238-44. PMID 5796743 DOI: 10.1016/0006-291X(69)90637-8  0.537
1969 Sherman MI, Simpson MV. The role of ribosomal conformation in protein biosynthesis: the streptomycin-ribosome interaction. Proceedings of the National Academy of Sciences of the United States of America. 64: 1388-95. PMID 4916926 DOI: 10.1073/Pnas.64.4.1388  0.388
1969 Sherman MI, Simpson MV. Ribosomal conformation changes during subunit dissociation and reassociation. Cold Spring Harbor Symposia On Quantitative Biology. 34: 220-2. PMID 4909501  0.242
1969 Sherman MI, Chuang DM, Simpson MV. Streptomycin and ribosome conformation changes. Cold Spring Harbor Symposia On Quantitative Biology. 34: 109-11. PMID 4909487  0.225
1969 Gantt RR, Englander SW, Simpson MV. Hydrogen-exchange measurements on Escherichia coli transfer ribonucleic acid before, after, and during its aminoacylation. Biochemistry. 8: 475-82. PMID 4893573  0.24
1968 Karol MH, Simpson MV. DNA biosynthesis by isolated mitochondria: a replicative rather than a repair process. Science (New York, N.Y.). 162: 470-3. PMID 5683057  0.44
1968 Meyer RR, Simpson MV. DNA biosynthesis in mitochondria: partial purification of a distinct DNA polymerase from isolated rat liver mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 61: 130-7. PMID 5246922 DOI: 10.1073/Pnas.61.1.130  0.523
1967 Parsons P, Simpson MV. Biosynthesis of DNA by isolated mitochondria: incorporation of thymidine triphosphate-2-C-14. Science (New York, N.Y.). 155: 91-3. PMID 6015569  0.453
1967 Page LA, Englander SW, Simpson MV. Hydrogen exchange studies on ribosomes Biochemistry. 6: 968-977. PMID 4962054 DOI: 10.1021/bi00856a003  0.215
1965 Dietz GW, Reid BR, Simpson MV. Ribosomes. A Study of Active and Sluggish Preparations* Biochemistry. 4: 2340-2350. DOI: 10.1021/Bi00887A012  0.227
1964 LUCAS JM, SCHUURS AH, SIMPSON MV. A CELL-FREE AMINO ACID-INCORPORATING SYSTEM FROM SACCHAROMYCES CEREVISIAE. VARIATION IN RIBOSOMAL ACTIVITY AND IN RNA SYNTHESIS DURING LOGARITHMIC GROWTH. Biochemistry. 3: 959-67. PMID 14214088  0.271
1962 SIMPSON MV. Protein biosynthesis. Annual Review of Biochemistry. 31: 333-68. PMID 13913227 DOI: 10.1146/annurev.bi.31.070162.002001  0.272
1961 SIMPSON MV, SKINNER DM, LUCAS JM. On the biosynthesis of cytochrome c. The Journal of Biological Chemistry. 236: PC81-PC82. PMID 13913226  0.238
1961 CRADDOCK VM, SIMPSON MV. Amino acid-activating enzymes in rat-liver mitochondria. The Biochemical Journal. 80: 348-52. PMID 13696172  0.338
1960 BATES HM, CRADDOCK VM, SIMPSON MV. The biosynthesis of cytochrome c in cell-free systems. I. The incorporation of labeled amino acids into cytochrome c by rat liver mitochondria. The Journal of Biological Chemistry. 235: 140-8. PMID 13797494  0.333
1959 KALF GF, SIMPSON MV. The incorporation of valine-1C14 into the protein of submitochondrial fractions. The Journal of Biological Chemistry. 234: 2943-7. PMID 14404104  0.284
1959 BATES HM, SIMPSON MV. The net synthesis of cytochrome c in calf-heart mitochondria. Biochimica Et Biophysica Acta. 32: 597-9. PMID 13797496  0.296
1959 KALF GF, BATES HM, SIMPSON MV. Protein synthesis in intact and sonically disrupted mitochondria. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 7: 245-7. PMID 13664972 DOI: 10.1177/7.4.245  0.368
1958 McLEAN JR, COHN GL, BRANDT IK, SIMPSON MV. Incorporation of labeled amino acids into the protein of muscle and liver mitochondria. The Journal of Biological Chemistry. 233: 657-63. PMID 13575431  0.329
1958 Bates HM, Craddock VM, Simpson MV. THE INCORPORATION OF VALINE-1-C14INTO CYTOCHROME c BY RAT LIVER MITOCHONDRIA1 Journal of the American Chemical Society. 80: 1000-1000. DOI: 10.1021/ja01537a064  0.328
1956 Light A, Simpson MV. Studies on the biosynthesis of insulin I. The paper chromatographic isolation of 14C-labeled insulin from calf pancreas slices Bba - General Subjects. 20: 251-261. PMID 13315372  0.268
1956 GRODSKY G, TARVER H, LIGHT A, SIMPSON MV. Paper chromatography of insulin. Nature. 177: 223-5. PMID 13297011 DOI: 10.1038/177223A0  0.647
1955 SIMPSON MV, MCLEAN JR. The incorporation of labeled amino acids into the cytoplasmic particles of rat muscle. Biochimica Et Biophysica Acta. 18: 573-5. PMID 13304047  0.251
1955 SIMPSON MV. Further studies on the biosynthesis of aldolase and glyceraldehyde-3-phosphate dehydrogenase The Journal of Biological Chemistry. 216: 179-183. PMID 13252017  0.269
1954 SIMPSON MV, VELICK SF. The synthesis of aldolase and glyceraldehyde-3-phosphate dehydrogenase in the rabbit. The Journal of Biological Chemistry. 208: 61-71. PMID 13174515  0.305
1953 SIMPSON MV. The release of labeled amino acids from the proteins of rat liver slices. The Journal of Biological Chemistry. 201: 143-54. PMID 13044783  0.315
1950 SIMPSON MV, TARVER H. Studies on protein synthesis in vitro; further observations on the incorporation of methionine into liver protein. Archives of Biochemistry. 25: 384-95. PMID 15404828  0.682
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