| Year |
Citation |
Score |
| 2011 |
Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. The Journal of Biological Chemistry. 286: 42316-24. PMID 22009749 DOI: 10.1074/Jbc.M111.286302 |
0.413 |
|
| 2010 |
Shen K, Qi L, Stiff L. Peptidomimetic competitive inhibitors of protein tyrosine phosphatases. Current Pharmaceutical Design. 16: 3101-17. PMID 20687872 |
0.36 |
|
| 2009 |
Shen K, Qi L, Ravula M, Klimaszewski K. Synthesis and peptide incorporation of an unnatural amino acid containing activity-based probe for protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry Letters. 19: 3264-7. PMID 19423347 DOI: 10.1016/J.Bmcl.2009.04.081 |
0.353 |
|
| 2009 |
Shen K, Qi L, Ravula M. Facile incorporation of a phosphatase activity-dependent quinone methide generating motif into phosphotyrosine Synthesis. 2009: 3765-3768. DOI: 10.1055/S-0029-1217025 |
0.38 |
|
| 2007 |
Shen K. Analyzing protein tyrosine phosphatases by phosphotyrosine analog integration Methods. 42: 234-242. PMID 17532510 DOI: 10.1016/j.ymeth.2007.03.003 |
0.324 |
|
| 2006 |
Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Cell. 125: 1137-1149. PMID 16777603 DOI: 10.1016/J.Cell.2006.05.013 |
0.401 |
|
| 2006 |
Cheng KY, Noble ME, Skamnaki V, Brown NR, Lowe ED, Kontogiannis L, Shen K, Cole PA, Siligardi G, Johnson LN. The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition. The Journal of Biological Chemistry. 281: 23167-79. PMID 16707497 DOI: 10.1074/Jbc.M600480200 |
0.39 |
|
| 2006 |
Levinson NM, Kuchment O, Shen K, Young MA, Koldobskiy M, Karplus M, Cole PA, Kuriyan J. A Src-like inactive conformation in the abl tyrosine kinase domain. Plos Biology. 4: e144. PMID 16640460 DOI: 10.1371/Journal.Pbio.0040144 |
0.457 |
|
| 2005 |
Shen K, Hines AC, Schwarzer D, Pickin KA, Cole PA. Protein kinase structure and function analysis with chemical tools. Biochimica Et Biophysica Acta. 1754: 65-78. PMID 16213197 DOI: 10.1016/J.Bbapap.2005.08.020 |
0.511 |
|
| 2003 |
Shen K, Cole PA. Conversion of a tyrosine kinase protein substrate to a high affinity ligand by ATP linkage. Journal of the American Chemical Society. 125: 16172-3. PMID 14692742 DOI: 10.1021/Ja0380401 |
0.457 |
|
| 2003 |
Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY. Cellular effects of small molecule PTP1B inhibitors on insulin signaling. Biochemistry. 42: 12792-804. PMID 14596593 DOI: 10.1021/Bi035238P |
0.498 |
|
| 2003 |
Cole PA, Shen K, Qiao Y, Wang D. Protein tyrosine kinases Src and Csk: a tail's tale. Current Opinion in Chemical Biology. 7: 580-5. PMID 14580561 DOI: 10.1016/J.Cbpa.2003.08.009 |
0.479 |
|
| 2003 |
Cole PA, Courtney AD, Shen K, Zhang Z, Qiao Y, Lu W, Williams DM. Chemical approaches to reversible protein phosphorylation. Accounts of Chemical Research. 36: 444-52. PMID 12809531 DOI: 10.1021/Ar0201254 |
0.432 |
|
| 2003 |
Lu W, Shen K, Cole PA. Chemical dissection of the effects of tyrosine phosphorylation of SHP-2. Biochemistry. 42: 5461-8. PMID 12731888 DOI: 10.1021/Bi0340144 |
0.457 |
|
| 2003 |
Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. The Journal of Biological Chemistry. 278: 12406-14. PMID 12547827 DOI: 10.1074/Jbc.M212491200 |
0.559 |
|
| 2003 |
Zhang Z, Shen K, Lu W, Cole PA. The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation. The Journal of Biological Chemistry. 278: 4668-74. PMID 12468540 DOI: 10.1074/Jbc.M210028200 |
0.494 |
|
| 2002 |
Guo XL, Shen K, Wang F, Lawrence DS, Zhang ZY. Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition. The Journal of Biological Chemistry. 277: 41014-22. PMID 12193602 DOI: 10.1074/Jbc.M207347200 |
0.564 |
|
| 2001 |
Shen K, Keng YF, Wu L, Guo XL, Lawrence DS, Zhang ZY. Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure. The Journal of Biological Chemistry. 276: 47311-9. PMID 11584002 DOI: 10.1074/Jbc.M106568200 |
0.55 |
|
| 2001 |
Zhou B, Wu L, Shen K, Zhang J, Lawrence DS, Zhang ZY. Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2. The Journal of Biological Chemistry. 276: 6506-15. PMID 11104775 DOI: 10.1074/Jbc.M009753200 |
0.545 |
|
| 1999 |
Taing M, Keng YF, Shen K, Wu L, Lawrence DS, Zhang ZY. Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B. Biochemistry. 38: 3793-803. PMID 10090769 DOI: 10.1021/Bi9813781 |
0.558 |
|
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