| Year |
Citation |
Score |
| 2025 |
Campbell K, Li Q. Clonal hematopoiesis JAKs up plaque formation. The Journal of Clinical Investigation. 135. PMID 39744945 DOI: 10.1172/JCI187529 |
0.305 |
|
| 2024 |
Zheng M, Peng Q, Kropp EM, Shen Z, Liu S, Yin Z, Matono S, Iwawaki T, Wang X, Inoki K, Mei Y, Li Q, Liu L. PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation. Biorxiv : the Preprint Server For Biology. PMID 39763724 DOI: 10.1101/2024.12.13.628451 |
0.491 |
|
| 2024 |
Pan S, Li Y, Wang L, Guan Y, Xv K, Li Q, Feng G, Hu Y, Lan X, Qin S, Gui L, Li L. Microenvironment-optimized gastrodin-functionalized scaffolds orchestrate asymmetric division of recruited stem cells in endogenous bone regeneration. Journal of Nanobiotechnology. 22: 722. PMID 39563380 DOI: 10.1186/s12951-024-02886-7 |
0.319 |
|
| 2024 |
Rosen BP, Li QV, Cho HS, Liu D, Yang D, Graff S, Yan J, Luo R, Verma N, Damodaran JR, Kale HT, Kaplan SJ, Beer MA, Sidoli S, Huangfu D. Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness. Nature Communications. 15: 8966. PMID 39419994 DOI: 10.1038/s41467-024-53284-4 |
0.365 |
|
| 2024 |
Huang Z, Chen Z, Ye T, Luo L, Zhang J, Li Q, Wang Y, Zhao B. Large extracellular vesicles from induced pluripotent stem cell-marrow stem cells enhance limb angiogenesis via ERK/MAPK. Nanomedicine (London, England). 1-15. PMID 39012207 DOI: 10.1080/17435889.2024.2363743 |
0.351 |
|
| 2023 |
Reynolds SB, Pettit K, Kandarpa M, Talpaz M, Li Q. Exploring the Molecular Landscape of Myelofibrosis, with a Focus on Ras and Mitogen-Activated Protein (MAP) Kinase Signaling. Cancers. 15. PMID 37760623 DOI: 10.3390/cancers15184654 |
0.361 |
|
| 2023 |
Ni ST, Li Q, Chen Y, Shi FL, Wong TS, Yuan LS, Xu R, Gan YQ, Lu N, Li YP, Zhou ZY, Xu LH, He XH, Hu B, Ouyang DY. Anti-Necroptotic Effects of Itaconate and its Derivatives. Inflammation. PMID 37759136 DOI: 10.1007/s10753-023-01909-z |
0.305 |
|
| 2023 |
Huang K, Cai S, Fu T, Zhu Q, Liu L, Yao Z, Rao P, Lan X, Li Q, Xiao J. Wnt10b regulates osteogenesis of adipose-derived stem cells through Wnt/β-catenin signalling pathway in osteoporosis. Cell Proliferation. e13522. PMID 37340715 DOI: 10.1111/cpr.13522 |
0.303 |
|
| 2023 |
Rosen BP, Li QV, Cho H, Liu D, Yang D, Graff S, Yan J, Luo R, Verma N, Damodaran JR, Beer MA, Sidoli S, Huangfu D. Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal. Biorxiv : the Preprint Server For Biology. PMID 37205540 DOI: 10.1101/2023.05.03.539283 |
0.334 |
|
| 2023 |
Li Q, Cui C, Liao R, Yin X, Wang D, Cheng Y, Huang B, Wang L, Yan M, Zhou J, Zhao J, Tang W, Wang Y, Wang X, Lv J, et al. The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice. Cellular and Molecular Life Sciences : Cmls. 80: 148. PMID 37178259 DOI: 10.1007/s00018-023-04794-9 |
0.312 |
|
| 2022 |
Liu W, Zhu X, Tang L, Shen N, Cheng F, Zou P, You Y, Yuan G, Li Q, Zhu X. ACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway. Scientific Reports. 12: 17990. PMID 36289272 DOI: 10.1038/s41598-022-21009-6 |
0.312 |
|
| 2022 |
Zi D, Li Q, Xu CX, Zhou ZW, Song GB, Hu CB, Wen F, Yang HL, Nie L, Zhao X, Tan J, Zhou SF, He ZX. CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma. Aging. 13. PMID 35681259 DOI: 10.18632/aging.203241 |
0.31 |
|
| 2022 |
Kim SH, Basili T, Dopeso H, Da Cruz Paula A, Bi R, Issa Bhaloo S, Pareja F, Li Q, da Silva EM, Zhu Y, Hoang T, Selenica P, Murali R, Chan E, Wu M, et al. Recurrent WWTR1 S89W mutations and Hippo pathway deregulation in clear cell carcinomas of the cervix. The Journal of Pathology. PMID 35411948 DOI: 10.1002/path.5910 |
0.353 |
|
| 2022 |
Jin X, Ng V, Zhao M, Liu L, Higashimoto T, Lee ZH, Chung J, Chen V, Ney G, Kandarpa M, Talpaz M, Li Q. Epigenetic Downregulation of Socs2 Contributes to Mutant N-Ras-Mediated Hematopoietic Dysregulation. Disease Models & Mechanisms. PMID 35352806 DOI: 10.1242/dmm.049088 |
0.819 |
|
| 2021 |
Kumar S, Jones M, Li Q, Lombard DB. Assessment of Cellular Bioenergetics in Mouse Hematopoietic Stem and Primitive Progenitor Cells using the Extracellular Flux Analyzer. Journal of Visualized Experiments : Jove. PMID 34633378 DOI: 10.3791/63045 |
0.596 |
|
| 2021 |
Yu L, Lemay P, Ludlow AV, Guyot MC, Jones MA, Mohamed FF, Saroya GA, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, et al. A new murine Rpl5(uL18) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia. Blood Advances. PMID 34464976 DOI: 10.1182/bloodadvances.2021004658 |
0.572 |
|
| 2021 |
Xu X, Xu Y, Guo R, Xu R, Fu C, Xing M, Sasanuma H, Li Q, Takata M, Takeda S, Guo R, Xu D. Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress. Nature Structural & Molecular Biology. 28: 487-500. PMID 34117478 DOI: 10.1038/s41594-021-00602-9 |
0.313 |
|
| 2021 |
Zhang H, Corredor ALG, Messina-Pacheco J, Li Q, Zogopoulos G, Kaddour N, Wang Y, Shi BY, Gregorieff A, Liu JL, Gao ZH. REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. Communications Biology. 4: 688. PMID 34099862 DOI: 10.1038/s42003-021-02193-z |
0.348 |
|
| 2021 |
Yang L, Li Q, Zhang J, Li P, An P, Wang C, Hu P, Zou X, Dou X, Zhu L. Wnt7a promotes the osteogenic differentiation of human mesenchymal stem cells. International Journal of Molecular Medicine. 47. PMID 33846764 DOI: 10.3892/ijmm.2021.4927 |
0.322 |
|
| 2021 |
Ney GM, Yang KB, Ng V, Liu L, Zhao M, Kuk W, Alaka L, Sampang L, Ross A, Jones MA, Jin X, McKay LM, Evarts H, Li Q. Oncogenic N-Ras mitigates oxidative stress-induced apoptosis of hematopoietic stem cells. Cancer Research. PMID 33441311 DOI: 10.1158/0008-5472.CAN-20-0118 |
0.8 |
|
| 2020 |
Liu L, Inoki A, Fan K, Mao F, Shi G, Jin X, Zhao M, Ney G, Jones MA, Sun S, Dou Y, Inoki K, Qi L, Li Q. ER associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity. Blood. PMID 33150381 DOI: 10.1182/blood.2020007975 |
0.809 |
|
| 2020 |
Gong L, Chen B, Zhang J, Sun Y, Yuan J, Niu X, Hu G, Chen Y, Xie Z, Deng Z, Li Q, Wang Y. Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. Journal of Extracellular Vesicles. 9: 1800971. PMID 32944188 DOI: 10.1080/20013078.2020.1800971 |
0.325 |
|
| 2020 |
Ney GM, McKay LM, Koschmann C, Mody R, Li Q. The Emerging Role of Ras Pathway Signaling in Pediatric Cancer. Cancer Research. PMID 32907837 DOI: 10.1158/0008-5472.Can-20-0916 |
0.755 |
|
| 2020 |
Li Q, Huang JC, Liao DY, Wu Y. Chidamide plus decitabine synergistically induces apoptosis of acute myeloid leukemia cells by upregulating . American Journal of Translational Research. 12: 3461-3475. PMID 32774712 |
0.321 |
|
| 2020 |
Zhang J, Xue W, Xu K, Yi L, Guo Y, Xie T, Tong H, Zhou B, Wang S, Li Q, Liu H, Chen X, Fang J, Zhang W. Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI. Theranostics. 10: 7245-7259. PMID 32641990 DOI: 10.7150/thno.44427 |
0.323 |
|
| 2020 |
Zhou ZW, Ambrogio C, Bera AK, Li Q, Li XX, Li L, Son J, Gondi S, Li J, Campbell E, Jin H, Okoro JJ, Xu CX, Janne PA, Westover KD. KRASQ61H preferentially signals through MAPK in a RAF dimer-dependent manner in non-small cell lung cancer. Cancer Research. PMID 32605999 DOI: 10.1158/0008-5472.Can-20-0448 |
0.383 |
|
| 2020 |
Jiang YL, Li Q, Yuan T, Jiang YY, Deng Q. Case Report of Anti-CD123 Chimeric Antigen Receptor T-Cell Therapy Followed by Radiotherapy for a Recurrence of Blastic Plasmacytoid Dendritic Cell Neoplasm After Allogeneic Hematopoietic Stem Cell Transplantation. Oncotargets and Therapy. 13: 3425-3430. PMID 32368098 DOI: 10.2147/OTT.S250016 |
0.307 |
|
| 2020 |
Ney GM, Anderson B, Bender J, Kumar-Sinha C, Wu YM, Vats P, Cieslik M, Robinson DR, Li Q, Chinnaiyan AM, Mody R. Mutations predictive of hyperactive Ras signaling correlate with inferior survival across high-risk pediatric acute leukemia. Translational Pediatrics. 9: 43-50. PMID 32154134 DOI: 10.21037/Tp.2019.12.03 |
0.737 |
|
| 2020 |
Wandler AM, Huang BJ, Craig JW, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Jonsson P, et al. Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia. PMID 32066867 DOI: 10.1038/S41375-020-0748-6 |
0.321 |
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| 2019 |
Yin Q, Wang H, Li N, Ding Y, Xie Z, Jin L, Li Y, Wang Q, Liu X, Xu L, Li Q, Ma Y, Cheng Y, Wang K, Zhong C, et al. Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1. Cell Research. PMID 31853004 DOI: 10.1038/S41422-019-0264-2 |
0.337 |
|
| 2019 |
Huang BJ, Wandler AM, Meyer LK, Dail M, Daemen A, Sampath D, Li Q, Wang X, Wong JC, Nakitandwe J, Downing JR, Zhang J, Taylor BS, Shannon K. Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias. Plos Genetics. 15: e1008168. PMID 31199785 DOI: 10.1371/Journal.Pgen.1008168 |
0.38 |
|
| 2019 |
Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh CL, Yang D, Crespo M, Shukla A, Xiang Q, Dündar F, Zumbo P, et al. Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nature Genetics. PMID 31110351 DOI: 10.1038/S41588-019-0408-9 |
0.355 |
|
| 2019 |
Liu L, Zhao M, Jin X, Ney G, Yang KB, Peng F, Cao J, Iwawaki T, Del Valle J, Chen X, Li Q. Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells. Nature Cell Biology. PMID 30778220 DOI: 10.1038/S41556-019-0285-6 |
0.797 |
|
| 2019 |
Lemay P, Jones MA, Mohamed F, Guyot M, Ludlow A, Li Q, Engel JD, Franceschi R, Rothstein TL, Kaartinen V, Kibar Z, Singh SA. Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis Blood. 134: 2495-2495. DOI: 10.1182/Blood-2019-131526 |
0.399 |
|
| 2019 |
Jones MA, Zhao M, Liu L, Feng Y, Ross A, Fearon ER, Li Q. Caudal Type Homeobox 2 Is Required for Leukemogenesis but Not for Normal Hematopoieisis Blood. 134: 3770-3770. DOI: 10.1182/Blood-2019-130985 |
0.74 |
|
| 2018 |
Li Q, Li Y, Yang S, Huang S, Yan M, Ding Y, Tang W, Lou X, Yin Q, Sun Z, Lu L, Shi H, Wang H, Chen Y, Li J. CRISPR-Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development. Nature Cell Biology. PMID 30275529 DOI: 10.1038/s41556-018-0202-4 |
0.319 |
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| 2018 |
Choi HK, Yuan H, Fang F, Wei X, Liu L, Li Q, Guan JL, Liu F. Tsc1 regulates the balance between osteoblast and adipocyte differentiation through autophagy/Notch1/β-catenin cascade. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29924882 DOI: 10.1002/Jbmr.3530 |
0.342 |
|
| 2018 |
Jin X, Qin T, Zhao M, Bailey N, Liu L, Yang K, Ng V, Higashimoto T, Coolon R, Ney G, Figueroa ME, Li Q. Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells. Blood Advances. 2: 1259-1271. PMID 29866713 DOI: 10.1182/Bloodadvances.2018017400 |
0.821 |
|
| 2018 |
Chapple RH, Hu T, Tseng YJ, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. Elife. 7. PMID 29451493 DOI: 10.7554/Elife.31159 |
0.729 |
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| 2018 |
Chapple RH, Hu T, Tseng Y, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D. Author response: ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response Elife. DOI: 10.7554/Elife.31159.023 |
0.665 |
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| 2018 |
Li Q. RAS-MAPK Pathway Signaling in Health and Disease Blood. 132. DOI: 10.1182/Blood-2018-99-109378 |
0.34 |
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| 2017 |
Lu J, Yao XQ, Luo X, Wang Y, Chung SK, Tang HX, Cheung CW, Wang XY, Meng C, Li Q. Monosialoganglioside 1 may alleviate neurotoxicity induced by propofol combined with remifentanil in neural stem cells. Neural Regeneration Research. 12: 945-952. PMID 28761428 DOI: 10.4103/1673-5374.208589 |
0.314 |
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| 2017 |
Zhu Y, Wang Y, Zhao B, Niu X, Hu B, Li Q, Zhang J, Ding J, Chen Y, Wang Y. Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis. Stem Cell Research & Therapy. 8: 64. PMID 28279188 DOI: 10.1186/s13287-017-0510-9 |
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| 2017 |
Liu X, Li Q, Niu X, Hu B, Chen S, Song W, Ding J, Zhang C, Wang Y. Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis. International Journal of Biological Sciences. 13: 232-244. PMID 28255275 DOI: 10.7150/ijbs.16951 |
0.342 |
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| 2017 |
Burgess MR, Hwang E, Mroue R, Bielski CM, Wandler AM, Huang BJ, Firestone AJ, Young A, Lacap JA, Crocker L, Asthana S, Davis EM, Xu J, Akagi K, Le Beau MM, ... Li Q, et al. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell. PMID 28215705 DOI: 10.1016/J.Cell.2017.01.020 |
0.385 |
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| 2017 |
Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, et al. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nature Medicine. PMID 28191887 DOI: 10.1038/Nm.4283 |
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| 2016 |
Tian XQ, Yang YJ, Li Q, Huang PS, Li XD, Jin C, Qi K, Jiang LP, Chen GH. Globular Adiponectin Inhibits the Apoptosis of Mesenchymal Stem Cells Induced by Hypoxia and Serum Deprivation via the AdipoR1-Mediated Pathway. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 909-925. PMID 26919192 DOI: 10.1159/000443044 |
0.34 |
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| 2016 |
Wandler AM, Huang B, Scacchetti A, Craig J, Yan H, Monsalve G, Li Q, Dail M, Wong JC, Nakitandwe J, Weinberg O, Hasserjian RP, Kogan SC, Sampath D, Downing JR, et al. Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression Blood. 128: 753-753. DOI: 10.1182/Blood.V128.22.753.753 |
0.363 |
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| 2016 |
Liu L, Zhao M, Yang KB, Jin X, Ney G, Del Valle J, Iwawaki T, Li Q. N-RasG12D-Mediated Dysregulation of IRE1alpha-Xbp1s Signaling Promotes Pre-Leukemic Hematopoietic Stem Cell Expansion Blood. 128: 567-567. DOI: 10.1182/Blood.V128.22.567.567 |
0.819 |
|
| 2016 |
Puissant A, Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, et al. Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia Blood. 128: 523-523. DOI: 10.1182/Blood.V128.22.523.523 |
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| 2016 |
Jin X, Qin T, Bailey NG, Zhao M, Yang KB, Ng V, Liu L, Coolon R, Ney G, Figueroa ME, Li Q. Hyperactive Nras and Dose Reduction of Tet2 Collaborate to Dys-Regulate Hematopoietic Stem Cells and Promote Leukemogenesis Blood. 128: 1204-1204. DOI: 10.1182/Blood.V128.22.1204.1204 |
0.82 |
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| 2015 |
Hu GW, Li Q, Niu X, Hu B, Liu J, Zhou SM, Guo SC, Lang HL, Zhang CQ, Wang Y, Deng ZF. Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice. Stem Cell Research & Therapy. 6: 10. PMID 26268554 DOI: 10.1186/scrt546 |
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| 2015 |
Yuan Z, Li Q, Luo S, Liu Z, Luo D, Zhang B, Zhang D, Rao P, Xiao J. PPARγ and Wnt Signaling in Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells. Current Stem Cell Research & Therapy. PMID 25986621 |
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| 2015 |
Cheng PP, Liu XC, Ma PF, Gao C, Li JL, Lin YY, Shao W, Han S, Zhao B, Wang LM, Fu JZ, Meng LX, Li Q, Lian QZ, Xia JJ, et al. iPSC-MSCs Combined with Low-Dose Rapamycin Induced Islet Allograft Tolerance Through Suppressing Th1 and Enhancing Regulatory T-Cell Differentiation. Stem Cells and Development. PMID 25867817 DOI: 10.1089/scd.2014.0488 |
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| 2015 |
Yang KB, Ng V, Ney G, Liu L, Jin X, Li Q. Oncogenic Nras Grants Apoptosis Resistance to Hematopoietic Stem Cells Blood. 126: 2451-2451. DOI: 10.1182/Blood.V126.23.2451.2451 |
0.84 |
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| 2014 |
Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. Preclinical efficacy of MEK inhibition in Nras-mutant AML. Blood. 124: 3947-55. PMID 25361812 DOI: 10.1182/Blood-2014-05-574582 |
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| 2014 |
Dail M, Wong J, Lawrence J, O'Connor D, Nakitandwe J, Chen SC, Xu J, Lee LB, Akagi K, Li Q, Aster JC, Pear WS, Downing JR, Sampath D, Shannon K. Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia. Nature. 513: 512-6. PMID 25043004 DOI: 10.1038/Nature13495 |
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| 2014 |
Chen CY, Liao W, Lou YL, Li Q, Hu B, Wang Y, Deng ZF. Inhibition of Notch signaling facilitates the differentiation of human-induced pluripotent stem cells into neural stem cells. Molecular and Cellular Biochemistry. 395: 291-8. PMID 24972705 DOI: 10.1007/s11010-014-2130-3 |
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| 2014 |
Hu B, Guo Y, Chen C, Li Q, Niu X, Guo S, Zhang A, Wang Y, Deng Z. Repression of SIRT1 promotes the differentiation of mouse induced pluripotent stem cells into neural stem cells. Cellular and Molecular Neurobiology. 34: 905-12. PMID 24832395 DOI: 10.1007/s10571-014-0071-8 |
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| 2014 |
Luo Y, Fan Y, Chen X, Yue L, Yu B, Li Q, Chen Y, Sun X. Modeling induced pluripotent stem cells from fibroblasts of Duchenne muscular dystrophy patients. The International Journal of Neuroscience. 124: 12-21. PMID 23528047 DOI: 10.3109/00207454.2013.789514 |
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Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Lowe SW, Shannon K, Li Q. Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia Blood. 124: 3753-3753. DOI: 10.1182/Blood.V124.21.3753.3753 |
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Li Q, Bohin N, Wen T, Ng V, Magee J, Chen SC, Shannon K, Morrison SJ. Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness. Nature. 504: 143-7. PMID 24284627 DOI: 10.1038/Nature12830 |
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Li Q, Wang Y, Deng Z. Pre-conditioned mesenchymal stem cells: a better way for cell-based therapy. Stem Cell Research & Therapy. 4: 63. PMID 23739590 DOI: 10.1186/scrt213 |
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Xu J, Haigis KM, Firestone AJ, McNerney ME, Li Q, Davis E, Chen SC, Nakitandwe J, Downing J, Jacks T, Le Beau MM, Shannon K. Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation. Cancer Discovery. 3: 993-1001. PMID 23733505 DOI: 10.1158/2159-8290.Cd-13-0096 |
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Li Q, Fan Y, Sun X, Yu Y. Generation of induced pluripotent stem cells from human amniotic fluid cells by reprogramming with two factors in feeder-free conditions Journal of Reproduction and Development. 59: 72-77. PMID 23138118 |
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Xu J, Hedberg C, Dekker FJ, Li Q, Haigis KM, Hwang E, Waldmann H, Shannon K. Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras. Blood. 119: 1032-5. PMID 22144181 DOI: 10.1182/Blood-2011-06-358960 |
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Li Q, Bohin N, Wen T, Shannon KM, Morrison SJ. Oncogenic Nras Increases Hematopoietic Stem Cell Proliferation and Self-Renewal Through a Bimodal Effect Blood. 120: 119-119. DOI: 10.1182/Blood.V120.21.119.119 |
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| 2011 |
Li Q, Haigis KM, McDaniel A, Harding-Theobald E, Kogan SC, Akagi K, Wong JC, Braun BS, Wolff L, Jacks T, Shannon K. Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus. Blood. 117: 2022-32. PMID 21163920 DOI: 10.1182/Blood-2010-04-280750 |
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| 2011 |
Shannon K, Li Q. Oncogenic Ras scales the ALPS Blood. 117: 2747-2748. DOI: 10.1182/Blood-2010-12-320721 |
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| 2010 |
Dail M, Li Q, McDaniel A, Wong J, Akagi K, Huang B, Kang HC, Kogan SC, Shokat K, Wolff L, Braun BS, Shannon K. Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents. Proceedings of the National Academy of Sciences of the United States of America. 107: 5106-11. PMID 20194733 DOI: 10.1073/Pnas.1001064107 |
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Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, et al. Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature. 461: 411-4. PMID 19727076 DOI: 10.1038/Nature08279 |
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Zhang F, Zhang L, Li F, Li H, Gu Y, Liu F, Li Q. Alteration of the critical cell cycle genes might contribute to carcinogenesis by disrupting the asymmetric division of somatic stem cells. Medical Hypotheses. 71: 977-8. PMID 18771861 DOI: 10.1016/j.mehy.2008.07.039 |
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Yan Q, Huang G, Li Q, Shi J, Cheng H, Wang W, Zhang F. Gene mutation might contribute to carcinogenesis by disrupting the asymmetric division of somatic stem cells. Medical Hypotheses. 70: 1230-1. PMID 18343597 DOI: 10.1016/j.mehy.2008.01.026 |
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