David Henshall - Publications

Affiliations: 
Physiology & Medical Physics Royal College of Surgeons, Ireland, Dublin, County Dublin, Ireland 

223 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Beamer E, Morgan J, Alves M, Méndez AM, Morris G, Zimmer B, Conte G, de Diego-Garcia L, Alarcón-Vila C, Ng NKY, Madden S, Calzaferri F, de Los Rios C, Garcia AG, Hamacher M, ... ... Henshall DC, et al. Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice. British Journal of Pharmacology. PMID 34962289 DOI: 10.1111/bph.15785  1
2021 Henshall DC, Guerrini R, Jozwiak S, Kokaia M, Pitkanen A, Sisodiya S, Simonato M, Cross JH, Ryvlin P, Brodie MJ, Trinka E, Sofia F. Meeting report: EpiXchange II brings together European epilepsy research projects to discuss latest advances. Epilepsy Research. 178: 106811. PMID 34814066 DOI: 10.1016/j.eplepsyres.2021.106811  1
2021 Conte G, Menéndez-Méndez A, Bauer S, El-Naggar H, Alves M, Nicke A, Delanty N, Rosenow F, Henshall DC, Engel T. Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy. Cells. 10. PMID 34572093 DOI: 10.3390/cells10092444  1
2021 Mooney C, O'Boyle D, Finder M, Hallberg B, Walsh BH, Henshall DC, Boylan GB, Murray DM. Predictive modelling of hypoxic ischaemic encephalopathy risk following perinatal asphyxia. Heliyon. 7: e07411. PMID 34278022 DOI: 10.1016/j.heliyon.2021.e07411  0.01
2021 Mathoux J, Henshall DC, Brennan GP. Regulatory Mechanisms of the RNA Modification mA and Significance in Brain Function in Health and Disease. Frontiers in Cellular Neuroscience. 15: 671932. PMID 34093133 DOI: 10.3389/fncel.2021.671932  1
2021 Morris G, O'Brien D, Henshall DC. Opportunities and challenges for microRNA-targeting therapeutics for epilepsy. Trends in Pharmacological Sciences. PMID 33992468 DOI: 10.1016/j.tips.2021.04.007  1
2021 Reschke CR, Silva LFA, Vangoor VR, Rosso M, David B, Cavanagh BL, Connolly NMC, Brennan GP, Sanz-Rodriguez A, Mooney C, Batool A, Greene C, Brennan M, Conroy RM, Rüber T, ... ... Henshall DC, et al. Systemic delivery of antagomirs during blood brain barrier disruption is disease-modifying in experimental epilepsy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33609732 DOI: 10.1016/j.ymthe.2021.02.021  1
2021 Beamer E, Lacey A, Alves M, Conte G, Tian F, de Diego-Garcia L, Khalil M, Rosenow F, Delanty N, Dale N, El-Naggar H, Henshall DC, Engel T. Elevated blood purine levels as a biomarker of seizures and epilepsy. Epilepsia. PMID 33599287 DOI: 10.1111/epi.16839  1
2021 Simonato M, Agoston DV, Brooks-Kayal A, Dulla C, Fureman B, Henshall DC, Pitkänen A, Theodore WH, Twyman RE, Kobeissy FH, Wang KK, Whittemore V, Wilcox KS. Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap. Nature Reviews. Neurology. PMID 33594276 DOI: 10.1038/s41582-021-00461-4  1
2021 Gomes-Duarte A, Bauer S, Venø MT, Norwood BA, Henshall DC, Kjems J, Rosenow F, Vangoor VR, Pasterkamp RJ. Enrichment of Circular RNA Expression Deregulation at the Transition to Recurrent Spontaneous Seizures in Experimental Temporal Lobe Epilepsy. Frontiers in Genetics. 12: 627907. PMID 33584828 DOI: 10.3389/fgene.2021.627907  1
2021 Gulcebi MI, Bartolini E, Lee O, Lisgaras CP, Onat F, Mifsud J, Striano P, Vezzani A, Hildebrand MS, Jimenez-Jimenez D, Junck L, Lewis-Smith D, Scheffer IE, Thijs RD, Zuberi SM, et al. Climate change and epilepsy: Insights from clinical and basic science studies. Epilepsy & Behavior : E&B. 116: 107791. PMID 33578223 DOI: 10.1016/j.yebeh.2021.107791  0.01
2021 Wilson MM, Henshall DC, Byrne SM, Brennan GP. CHD2-Related CNS Pathologies. International Journal of Molecular Sciences. 22. PMID 33435571 DOI: 10.3390/ijms22020588  1
2021 Campbell A, Morris G, Heller JP, Langa E, Brindley E, Worm J, Jensen MA, Miller MT, Henshall DC, Reschke CR. Antagomir-mediated suppression of microRNA-134 reduces kainic acid-induced seizures in immature mice. Scientific Reports. 11: 340. PMID 33431894 DOI: 10.1038/s41598-020-79350-7  1
2020 Carneiro CFD, Queiroz VGS, Moulin TC, Carvalho CAM, Haas CB, Rayêe D, Henshall DE, De-Souza EA, Amorim FE, Boos FZ, Guercio GD, Costa IR, Hajdu KL, van Egmond L, Modrák M, et al. Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature. Research Integrity and Peer Review. 5: 16. PMID 33292815 DOI: 10.1186/s41073-020-00101-3  0.01
2020 Conboy K, Henshall DC, Brennan GP. Epigenetic principles underlying epileptogenesis and epilepsy syndromes. Neurobiology of Disease. 105179. PMID 33181318 DOI: 10.1016/j.nbd.2020.105179  1
2020 Conte G, Parras A, Alves M, Ollà I, De Diego-Garcia L, Beamer E, Alalqam R, Ocampo A, Mendez R, Henshall DC, Lucas JJ, Engel T. High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsy. Epilepsia. PMID 33070315 DOI: 10.1111/epi.16714  1
2020 Conte G, Nguyen NT, Alves M, de Diego-Garcia L, Kenny A, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice. Frontiers in Molecular Neuroscience. 13: 127. PMID 32982684 DOI: 10.3389/Fnmol.2020.00127  1
2020 Rannikmäe K, Henshall DE, Thrippleton S, Ginj Kong Q, Chong M, Grami N, Kuan I, Wilkinson T, Wilson B, Wilson K, Paré G, Sudlow C. Beyond the Brain: Systematic Review of Extracerebral Phenotypes Associated With Monogenic Cerebral Small Vessel Disease. Stroke. STROKEAHA120029517. PMID 32842921 DOI: 10.1161/STROKEAHA.120.029517  1
2020 Almeida Silva LF, Reschke CR, Nguyen NT, Langa E, Sanz-Rodriguez A, Gerbatin RR, Temp FR, de Freitas ML, Conroy RM, Brennan GP, Engel T, Henshall DC. Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice. Molecular Brain. 13: 114. PMID 32825833 DOI: 10.1186/s13041-020-00653-x  1
2020 Brennan GP, Bauer S, Engel T, Jimenez-Mateos EM, Del Gallo F, Hill TDM, Connolly NMC, Costard LS, Neubert V, Salvetti B, Sanz-Rodriguez A, Heiland M, Mamad O, Brindley E, Norwood B, ... ... Henshall DC, et al. Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy. Neurobiology of Disease. 144: 105048. PMID 32800995 DOI: 10.1016/J.Nbd.2020.105048  1
2020 Casey S, Goasdoue K, Miller SM, Brennan GP, Cowin G, O'Mahony AG, Burke C, Hallberg B, Boylan GB, Sullivan AM, Henshall DC, O'Keeffe GW, Mooney C, Bjorkman T, Murray DM. Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury. Molecular Neurobiology. PMID 32720074 DOI: 10.1007/S12035-020-02018-W  1
2020 Rannikmäe K, Ngoh K, Bush K, Al-Shahi Salman R, Doubal F, Flaig R, Henshall DE, Hutchison A, Nolan J, Osborne S, Samarasekera N, Schnier C, Whiteley W, Wilkinson T, Wilson K, et al. Accuracy of identifying incident stroke cases from linked health care data in UK Biobank. Neurology. PMID 32616677 DOI: 10.1212/WNL.0000000000009924  1
2020 Parras A, de Diego-Garcia L, Alves M, Beamer E, Conte G, Jimenez-Mateos EM, Morgan J, Ollà I, Hernandez-Santana Y, Delanty N, Farrell MA, O'Brien DF, Ocampo A, Henshall DC, Méndez R, et al. Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy. Brain : a Journal of Neurology. PMID 32594159 DOI: 10.1093/brain/awaa168  1
2020 Venø MT, Reschke CR, Morris G, Connolly NMC, Su J, Yan Y, Engel T, Jimenez-Mateos EM, Harder LM, Pultz D, Haunsberger SJ, Pal A, Heller JP, Campbell A, Langa E, ... ... Henshall DC, et al. A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32581127 DOI: 10.1073/Pnas.1919313117  1
2020 Brennan GP, Henshall DC. MicroRNAs as regulators of brain function and targets for treatment of epilepsy. Nature Reviews. Neurology. PMID 32546757 DOI: 10.1038/s41582-020-0369-8  1
2020 McArdle H, Hogg MC, Bauer S, Rosenow F, Prehn JHM, Adamson K, Henshall DC, Spain E. Quantification of tRNA fragments by electrochemical direct detection in small volume biofluid samples. Scientific Reports. 10: 7516. PMID 32371908 DOI: 10.1038/S41598-020-64485-4  1
2020 Kobow K, Reid CA, van Vliet EA, Becker AJ, Carvill GL, Goldman AM, Hirose S, Lopes-Cendes I, Khiari HM, Poduri A, Johnson MR, Henshall DC. Epigenetics explained: a topic "primer" for the epilepsy community by the ILAE Genetics/Epigenetics Task Force. Epileptic Disorders : International Epilepsy Journal With Videotape. PMID 32301721 DOI: 10.1684/epd.2020.1143  1
2020 Yang M, Liu M, Ding Y, Vajda A, Ma J, Cui H, O'Brien T, Henshall D, Hardiman O, Shen S. Generation of twelve induced pluripotent stem cell lines from two healthy controls and two patients with sporadic amyotrophic lateral sclerosis. Stem Cell Research. 44: 101752. PMID 32208303 DOI: 10.1016/J.Scr.2020.101752  1
2020 Grami N, Chong M, Lali R, Mohammadi-Shemirani P, Henshall DE, Rannikmäe K, Paré G. Global Assessment of Mendelian Stroke Genetic Prevalence in 101 635 Individuals From 7 Ethnic Groups. Stroke. STROKEAHA119028840. PMID 32106772 DOI: 10.1161/STROKEAHA.119.028840  1
2020 De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, et al. Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32059764 DOI: 10.1016/J.Ymthe.2020.02.001  1
2020 Mooney C, McKiernan PJ, Raoof R, Henshall DC, Linnane B, McNally P, Glasgow AMA, Greene CM. Plasma microRNA levels in male and female children with cystic fibrosis. Scientific Reports. 10: 1141. PMID 31980676 DOI: 10.1038/S41598-020-57964-1  1
2020 Traynelis SF, Dlugos D, Henshall D, Mefford HC, Rogawski MA, Staley KJ, Dacks PA, Whittemore V, Poduri A. 2020 Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects. Epilepsy Currents. 1535759719895279. PMID 31965829 DOI: 10.1177/1535759719895279  0.01
2019 Batool A, Hill TDM, Nguyen NT, Langa E, Diviney M, Mooney C, Brennan GP, Connolly NMC, Sanz-Rodriguez A, Cavanagh BL, Henshall DC. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in Neuroscience. 13: 1404. PMID 32009885 DOI: 10.3389/fnins.2019.01404  1
2019 Kenny A, McArdle H, Calero M, Rabano A, Madden SF, Adamson K, Forster R, Spain E, Prehn JHM, Henshall DC, Medina M, Jimenez-Mateos EM, Engel T. Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment. Biomolecules. 9. PMID 31766231 DOI: 10.3390/biom9110734  1
2019 Kenny A, Jiménez-Mateos EM, Zea-Sevilla MA, Rábano A, Gili-Manzanaro P, Prehn JHM, Henshall DC, Ávila J, Engel T, Hernández F. Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer's disease. Scientific Reports. 9: 15437. PMID 31659197 DOI: 10.1038/s41598-019-51837-y  1
2019 Yang M, Liu M, Vajda A, O'Brien T, Henshall D, Hardiman O, Shen S. Generation of six induced pluripotent stem cell (iPSC) lines from two patients with amyotrophic lateral sclerosis (NUIGi043-A, NUIGi043-B, NUIGi043-C, NUIGi044-A, NUIGi044-B, NUIGi044-C). Stem Cell Research. 40: 101558. PMID 31514057 DOI: 10.1016/J.Scr.2019.101558  1
2019 Henshall DC. Brain delivery of a virus to block seizures helps mice get a silent NACHT. Ebiomedicine. PMID 31474550 DOI: 10.1016/j.ebiom.2019.08.066  0.01
2019 Quinlan S, Merino-Serrais P, Di Grande A, Dussmann H, Prehn JHM, Ní Chonghaile T, Henshall DC, Jimenez-Mateos EM. The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia. Frontiers in Immunology. 10: 1752. PMID 31396238 DOI: 10.3389/fimmu.2019.01752  1
2019 Liu J, McDaid L, Araque A, Wade J, Harkin J, Karim S, Henshall DC, Connolly NMC, Johnson AP, Tyrrell AM, Timmis J, Millard AG, Hilder J, Halliday DM. GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model. Frontiers in Cellular Neuroscience. 13: 335. PMID 31396055 DOI: 10.3389/Fncel.2019.00335  0.01
2019 Morris G, Reschke CR, Henshall DC. Targeting microRNA-134 for seizure control and disease modification in epilepsy. Ebiomedicine. PMID 31300345 DOI: 10.1016/J.Ebiom.2019.07.008  1
2019 Henshall DC. Epigenetics and noncoding RNA: Recent developments and future therapeutic opportunities. European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. PMID 31235424 DOI: 10.1016/j.ejpn.2019.06.002  0.01
2019 Pitkänen A, Henshall DC, Cross JH, Guerrini R, Jozwiak S, Kokaia M, Simonato M, Sisodiya S, Mifsud J. Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy. Epilepsia. PMID 31211425 DOI: 10.1111/epi.16091  1
2019 Costard LS, Neubert V, Venø MT, Su J, Kjems J, Connolly NMC, Prehn JHM, Schratt G, Henshall DC, Rosenow F, Bauer S. Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression. Brain Stimulation. PMID 31208877 DOI: 10.1016/J.Brs.2019.06.009  1
2019 Brindley E, Hill TDM, Henshall DC. MicroRNAs as biomarkers and treatment targets in status epilepticus. Epilepsy & Behavior : E&B. PMID 31171435 DOI: 10.1016/j.yebeh.2019.04.025  1
2019 Alves M, De Diego Garcia L, Conte G, Jimenez-Mateos EM, D'Orsi B, Sanz-Rodriguez A, Prehn JH, Henshall DC, Engel T. Context-specific switch from anti- to pro-epileptogenic function of the P2Y receptor in experimental epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31048325 DOI: 10.1523/JNEUROSCI.0089-19.2019  1
2019 Hogg MC, Raoof R, El Naggar H, Monsefi N, Delanty N, O'Brien DF, Bauer S, Rosenow F, Henshall DC, Prehn JH. Elevation in plasma tRNA fragments precede seizures in human epilepsy. The Journal of Clinical Investigation. 130. PMID 31039137 DOI: 10.1172/JCI126346  1
2019 Vangoor VR, Reschke CR, Senthilkumar K, van de Haar LL, de Wit M, Giuliani G, Broekhoven MH, Morris G, Engel T, Brennan GP, Conroy RM, van Rijen PC, Gosselaar PH, Schorge S, Schaapveld RQJ, ... Henshall DC, et al. Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31015341 DOI: 10.1523/Jneurosci.3014-18.2019  1
2019 Wilkinson T, Schnier C, Bush K, Rannikmäe K, Henshall DE, Lerpiniere C, Allen NE, Flaig R, Russ TC, Bathgate D, Pal S, O'Brien JT, Sudlow CLM. Identifying dementia outcomes in UK Biobank: a validation study of primary care, hospital admissions and mortality data. European Journal of Epidemiology. PMID 30806901 DOI: 10.1007/S10654-019-00499-1  1
2019 Rogers M, Boland B, Clarke S, Craven A, Fassbender C, Gill M, Hardiman O, Henshall DC, Lynch T, Mitchell K, Pender N, Rogan C, Roche RA. Building a Supportive Framework for Brain Research in Ireland: Inaugural Position Paper of The Irish Brain Council. The European Journal of Neuroscience. PMID 30673123 DOI: 10.1111/Ejn.14351  1
2019 Morris G, Veno M, Reschke C, Bauer S, Yan Y, Engel T, Pasterkamp RJ, Prehn JH, Schorge S, Rosenow F, Kjems J, Henshall DC. Argonaute-2 sequencing of rodent status epilepticus models identifies multiple microRNA targets for seizure suppression Epilepsy & Behavior. 101: 106737. DOI: 10.1016/J.Yebeh.2019.08.012  0.01
2018 Kenny A, Hernández F, Avila J, Lucas JJ, Henshall DC, Prehn JH, Jiménez-Mateos EM, Engel T. Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17. International Journal of Physiology, Pathophysiology and Pharmacology. 10: 172-183. PMID 30697364  1
2018 Beamer EH, Jurado-Arjona J, Jimenez-Mateos EM, Morgan J, Reschke CR, Kenny A, de Leo G, Olivos-Oré LA, Arribas-Blázquez M, Madden SF, Merchán-Rubira J, Delanty N, Farrell MA, O'Brien DF, Avila J, ... ... Henshall DC, et al. MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus. Frontiers in Molecular Neuroscience. 11: 442. PMID 30618601 DOI: 10.3389/fnmol.2018.00442  1
2018 Enright N, Simonato M, Henshall DC. Discovery and validation of blood microRNAs as molecular biomarkers of epilepsy: Ways to close current knowledge gaps. Epilepsia Open. 3: 427-436. PMID 30525113 DOI: 10.1002/epi4.12275  1
2018 Brennan GP, Vitsios DM, Casey S, Looney AM, Hallberg B, Henshall DC, Boylan GB, Murray DM, Mooney C. RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns. Plos One. 13: e0207952. PMID 30507953 DOI: 10.1371/journal.pone.0207952  1
2018 Raoof R, Bauer S, El Naggar H, Connolly NMC, Brennan GP, Brindley E, Hill T, McArdle H, Spain E, Forster RJ, Prehn JHM, Hamer H, Delanty N, Rosenow F, Mooney C, ... Henshall DC, et al. Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy. Ebiomedicine. PMID 30396857 DOI: 10.1016/J.Ebiom.2018.10.068  1
2018 Engel T, Gómez-Sintes R, Alves M, Jimenez-Mateos EM, Fernández-Nogales M, Sanz-Rodriguez A, Morgan J, Beamer E, Rodríguez-Matellán A, Dunleavy M, Sano T, Avila J, Medina M, Hernandez F, Lucas JJ, ... Henshall DC, et al. Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus. Cell Death & Disease. 9: 969. PMID 30237424 DOI: 10.1038/s41419-018-0963-5  1
2018 Henshall DC. Epigenetic changes in status epilepticus. Epilepsia. PMID 30159897 DOI: 10.1111/epi.14502  0.01
2018 Morris G, Brennan GP, Reschke CR, Henshall DC, Schorge S. Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA-134. Epilepsia. PMID 29978460 DOI: 10.1111/Epi.14475  1
2018 Quinlan SMM, Rodriguez-Alvarez N, Molloy EJ, Madden SF, Boylan GB, Henshall DC, Jimenez-Mateos EM. Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures. Scientific Reports. 8: 9986. PMID 29968748 DOI: 10.1038/s41598-018-28044-2  1
2018 Reschke CR, Poersch AB, Masson CJ, Jesse AC, Marafiga JR, Lenz QF, Oliveira MS, Henshall DC, Mello CF. Systemic delivery of selective EP1 and EP3 receptor antagonists attenuates pentylenetetrazole-induced seizures in mice. International Journal of Physiology, Pathophysiology and Pharmacology. 10: 47-59. PMID 29593850  1
2018 Sebastián-Serrano Á, de Diego-García L, Henshall DC, Engel T, Díaz-Hernández M. Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels. Frontiers in Pharmacology. 9: 170. PMID 29551976 DOI: 10.3389/fphar.2018.00170  1
2018 Henshall DE, Innes CW, Morrison SR, Wilson B, Brown RA, McAllister SM, Culshaw SL, Reda E. A prospective observational study of emergency department presentations following novel psychoactive substance use. Scottish Medical Journal. 36933018760761. PMID 29514583 DOI: 10.1177/0036933018760761  0.04
2018 Brennan GP, Henshall DC. microRNAs in the pathophysiology of epilepsy. Neuroscience Letters. 667: 47-52. PMID 28104433 DOI: 10.1016/j.neulet.2017.01.017  1
2018 Jimenez-Mateos EM, Henshall DC. Could miR-134 be a marker of ionizing radiation toxicity? Non-Coding Rna Investigation. 2: 24-24. DOI: 10.21037/NCRI.2018.04.04  0.01
2018 Glasgow A, Vencken S, Santi CD, Raoof R, Henshall D, Linnane B, Mcnally P, Greene C. The TLR4 regulator miR-21 is downregulated in the paediatric cystic fibrosis airway European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa3420  1
2017 Bielefeld P, Mooney C, Henshall DC, Fitzsimons CP. miRNA-Mediated Regulation of Adult Hippocampal Neurogenesis; Implications for Epilepsy. Brain Plasticity (Amsterdam, Netherlands). 3: 43-59. PMID 29765859 DOI: 10.3233/BPL-160036  1
2017 Rodriguez AS, Engel T, Palfi A, Farrar GJ, Henshall DC, Jimenez-Mateos EM. Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy. International Journal of Physiology, Pathophysiology and Pharmacology. 9: 178-187. PMID 29348794  1
2017 Alves M, Gomez-Villafuertes R, Delanty N, Farrell MA, O'Brien DF, Miras-Portugal MT, Hernandez MD, Henshall DC, Engel T. Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy. Epilepsia. PMID 28733972 DOI: 10.1111/epi.13850  1
2017 Aronica E, Bauer S, Bozzi Y, Caleo M, Dingledine R, Gorter JA, Henshall DC, Kaufer D, Koh S, Löscher W, Louboutin JP, Mishto M, Norwood BA, Palma E, Poulter MO, et al. Neuroinflammatory targets and treatments for epilepsy validated in experimental models. Epilepsia. 58: 27-38. PMID 28675563 DOI: 10.1111/Epi.13783  1
2017 Engel T, Lucas JJ, Henshall DC. Targeting the proteasome in epilepsy. Oncotarget. PMID 28611313 DOI: 10.18632/oncotarget.18418  1
2017 Raoof R, Jimenez-Mateos EM, Bauer S, Tackenberg B, Rosenow F, Lang J, Onugoren MD, Hamer H, Huchtemann T, Körtvélyessy P, Connolly NMC, Pfeiffer S, Prehn JHM, Farrell MA, O'Brien DF, ... Henshall DC, et al. Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus. Scientific Reports. 7: 3328. PMID 28607431 DOI: 10.1038/S41598-017-02969-6  1
2017 McArdle H, Jimenez-Mateos EM, Raoof R, Carthy E, Boyle D, ElNaggar H, Delanty N, Hamer H, Dogan M, Huchtemann T, Kӧrtvelyessy P, Rosenow F, Forster RJ, Henshall DC, Spain E. "TORNADO" - Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid. Scientific Reports. 7: 1750. PMID 28496112 DOI: 10.1038/S41598-017-01947-2  1
2017 Rajman M, Metge F, Fiore R, Khudayberdiev S, Aksoy-Aksel A, Bicker S, Ruedell Reschke C, Raoof R, Brennan GP, Delanty N, Farrell MA, O'Brien DF, Bauer S, Norwood B, Veno MT, ... ... Henshall DC, et al. A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. The Embo Journal. PMID 28487411 DOI: 10.15252/Embj.201695748  1
2017 Hauser RM, Henshall DC, Lubin FD. The Epigenetics of Epilepsy and Its Progression. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858417705840. PMID 28468530 DOI: 10.1177/1073858417705840  0.01
2017 Reynolds JP, Jimenez-Mateos EM, Cao L, Bian F, Alves M, Miller-Delaney SF, Zhou A, Henshall DC. Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury. Neurochemical Research. PMID 28397067 DOI: 10.1007/s11064-017-2260-6  1
2017 Henshall DC. Manipulating MicroRNAs in Murine Models: Targeting the Multi-Targeting in Epilepsy. Epilepsy Currents. 17: 43-47. PMID 28331471 DOI: 10.5698/1535-7511-17.1.43  0.01
2017 Reschke CR, Silva LF, Norwood BA, Senthilkumar K, Morris G, Sanz-Rodriguez A, Conroy RM, Costard L, Neubert V, Bauer S, Farrell MA, O'Brien DF, Delanty N, Schorge S, Pasterkamp RJ, ... ... Henshall DC, et al. Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy. Molecular Therapy. Nucleic Acids. 6: 45-56. PMID 28325299 DOI: 10.1016/J.Omtn.2016.11.002  1
2017 Engel T, Martinez-Villarreal J, Henke C, Jimenez-Mateos EM, Sanz-Rodriguez A, Alves M, Hernandez-Santana Y, Brennan GP, Kenny A, Campbell A, Lucas JJ, Henshall DC. Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury. Molecular Neurodegeneration. 12: 21. PMID 28235423 DOI: 10.1186/s13024-017-0163-2  1
2017 Mooney CM, Jimenez-Mateos EM, Engel T, Mooney C, Diviney M, Venø MT, Kjems J, Farrell MA, O'Brien DF, Delanty N, Henshall DC. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Scientific Reports. 7: 41517. PMID 28128343 DOI: 10.1038/Srep41517  1
2017 Rodriguez-Alvarez N, Jimenez-Mateos EM, Engel T, Quinlan S, Reschke CR, Conroy RM, Bhattacharya A, Boylan GB, Henshall DC. Effects of P2X7 receptor antagonists on hypoxia-induced neonatal seizures in mice. Neuropharmacology. PMID 28082183 DOI: 10.1016/j.neuropharm.2017.01.005  1
2017 Ichikawa N, Alves M, Pfeiffer S, Langa E, Hernández-Santana YE, Suzuki H, Prehn JH, Engel T, Henshall DC. Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice. Cell Death & Disease. 8: e2556. PMID 28079889 DOI: 10.1038/cddis.2016.301  1
2017 Engel T, Brennan GP, Sanz-Rodriguez A, Alves M, Beamer E, Watters O, Henshall DC, Jimenez-Mateos EM. A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22. Biochimica Et Biophysica Acta. Molecular Cell Research. 1864: 255-266. PMID 27840225 DOI: 10.1016/j.bbamcr.2016.11.007  1
2017 Quinlan S, Henke C, Brennan GP, Henshall DC, Jimenez-Mateos EM. Detection of MicroRNAs in Brain Slices Using In Situ Hybridization. Methods in Molecular Biology (Clifton, N.J.). 1509: 85-91. PMID 27826920 DOI: 10.1007/978-1-4939-6524-3_9  1
2016 Petit EI, Michalak Z, Cox R, O'Tuathaigh CM, Clarke N, Tighe O, Talbot K, Blake D, Joel J, Shaw A, Sheardown SA, Morrison AD, Wilson S, Shapland EM, Henshall DC, et al. Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27986973 DOI: 10.1038/npp.2016.282  1
2016 Henshall DC, Hamer HM, Pasterkamp RJ, Goldstein DB, Kjems J, Prehn JHM, Schorge S, Lamottke K, Rosenow F. MicroRNAs in epilepsy: pathophysiology and clinical utility. The Lancet. Neurology. 15: 1368-1376. PMID 27839653 DOI: 10.1016/S1474-4422(16)30246-0  1
2016 Almeida Silva LF, Engel T, Reschke CR, Conroy RM, Langa E, Henshall DC. Distinct behavioral and epileptic phenotype differences in 129/P mice compared to C57BL/6 mice subject to intraamygdala kainic acid-induced status epilepticus. Epilepsy & Behavior : E&B. 64: 186-194. PMID 27744244 DOI: 10.1016/j.yebeh.2016.09.031  1
2016 Gross C, Yao X, Engel T, Tiwari D, Xing L, Rowley S, Danielson SW, Thomas KT, Jimenez-Mateos EM, Schroeder LM, Pun RY, Danzer SC, Henshall DC, Bassell GJ. MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset. Cell Reports. 17: 37-45. PMID 27681419 DOI: 10.1016/J.Celrep.2016.08.074  1
2016 Sebastián-Serrano Á, Engel T, de Diego-García L, Olivos-Oré LA, Arribas-Blázquez M, Martínez-Frailes C, Pérez-Díaz C, Millán JL, Artalejo AR, Miras-Portugal MT, Henshall DC, Díaz-Hernández M. Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. Human Molecular Genetics. PMID 27466191 DOI: 10.1093/hmg/ddw248  1
2016 Fischer W, Franke H, Krügel U, Müller H, Dinkel K, Lord B, Letavic MA, Henshall DC, Engel T. Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models. Plos One. 11: e0156468. PMID 27281030 DOI: 10.1371/journal.pone.0156468  1
2016 Jimenez-Pacheco A, Diaz-Hernandez M, Arribas-Blázquez M, Sanz-Rodriguez A, Olivos-Oré LA, Artalejo AR, Alves M, Letavic M, Miras-Portugal MT, Conroy RM, Delanty N, Farrell MA, O'Brien DF, Bhattacharya A, Engel T, ... Henshall DC, et al. Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5920-32. PMID 27251615 DOI: 10.1523/JNEUROSCI.4009-15.2016  1
2016 Cattani AA, Allene C, Seifert V, Rosenow F, Henshall DC, Freiman TM. Involvement of microRNAs in epileptogenesis. Epilepsia. PMID 27207608 DOI: 10.1111/Epi.13404  1
2016 D'Orsi B, Engel T, Pfeiffer S, Nandi S, Kaufmann T, Henshall DC, Prehn JH. Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4564-78. PMID 27098698 DOI: 10.1523/JNEUROSCI.3780-15.2016  1
2016 Mooney C, Becker BA, Raoof R, Henshall DC. EpimiRBase: a comprehensive database of microRNA-epilepsy associations. Bioinformatics (Oxford, England). PMID 26748106 DOI: 10.1093/bioinformatics/btw008  1
2016 Engel T, Alves M, Sheedy C, Henshall DC. ATPergic signalling during seizures and epilepsy. Neuropharmacology. 104: 140-53. PMID 26549853 DOI: 10.1016/j.neuropharm.2015.11.001  1
2016 McKiernan P, Mooney C, Henshall D, Linnane B, McNally P, Greene C. Serum microRNA levels in paediatric females versus males with cystic fibrosis European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa898  1
2016 Engel T, Alves M, Sheedy C, Henshall DC. ATPergic signalling during seizures and epilepsy Neuropharmacology. 104: 140-153. DOI: 10.1016/j.neuropharm.2015.11.001  1
2015 Mooney C, Raoof R, El-Naggar H, Sanz-Rodriguez A, Jimenez-Mateos EM, Henshall DC. High Throughput qPCR Expression Profiling of Circulating MicroRNAs Reveals Minimal Sex- and Sample Timing-Related Variation in Plasma of Healthy Volunteers. Plos One. 10: e0145316. PMID 26699132 DOI: 10.1371/journal.pone.0145316  1
2015 Reschke CR, Henshall DC. microRNA and Epilepsy. Advances in Experimental Medicine and Biology. 888: 41-70. PMID 26663178 DOI: 10.1007/978-3-319-22671-2_4  1
2015 Jimenez-Mateos EM, Arribas-Blazquez M, Sanz-Rodriguez A, Concannon C, Olivos-Ore LA, Reschke CR, Mooney CM, Mooney C, Lugara E, Morgan J, Langa E, Jimenez-Pacheco A, Silva LF, Mesuret G, Boison D, ... ... Henshall DC, et al. microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. Scientific Reports. 5: 17486. PMID 26631939 DOI: 10.1038/srep17486  1
2015 Henshall DC, Kobow K. Epigenetics and Epilepsy. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26438606 DOI: 10.1101/cshperspect.a022731  0.01
2015 Rodriguez-Alvarez N, Jimenez-Mateos EM, Dunleavy M, Waddington JL, Boylan GB, Henshall DC. Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice. Neurobiology of Disease. 83: 100-14. PMID 26341542 DOI: 10.1016/j.nbd.2015.08.023  1
2015 Diviney M, Reynolds JP, Henshall DC. Comparison of short-term effects of midazolam and lorazepam in the intra-amygdala kainic acid model of status epilepticus in mice. Epilepsy & Behavior : E&B. 51: 191-198. PMID 26291773 DOI: 10.1016/j.yebeh.2015.07.038  1
2015 Brennan GP, Jimenez-Mateos EM, Sanz-Rodriguez A, Mooney CM, Tzivion G, Henshall DC, Engel T. Overexpression of 14-3-3ζ Increases Brain Levels of C/EBP Homologous Protein CHOP. Journal of Molecular Neuroscience : Mn. 56: 255-62. PMID 25854777 DOI: 10.1007/S12031-015-0510-0  1
2015 Henshall DC, Engel T. P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus. Epilepsy & Behavior : E&B. 49: 8-12. PMID 25843343 DOI: 10.1016/j.yebeh.2015.02.031  1
2015 Reynolds JP, Miller-Delaney SF, Jimenez-Mateos EM, Sano T, McKiernan RC, Simon RP, Henshall DC. Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning. Frontiers in Neurology. 6: 46. PMID 25806020 DOI: 10.3389/fneur.2015.00046  1
2015 D'Orsi B, Kilbride SM, Chen G, Perez Alvarez S, Bonner HP, Pfeiffer S, Plesnila N, Engel T, Henshall DC, Düssmann H, Prehn JH. Bax regulates neuronal Ca2+ homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1706-22. PMID 25632145 DOI: 10.1523/JNEUROSCI.2453-14.2015  1
2015 Miller-Delaney SF, Bryan K, Das S, McKiernan RC, Bray IM, Reynolds JP, Gwinn R, Stallings RL, Henshall DC. Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy. Brain : a Journal of Neurology. 138: 616-31. PMID 25552301 DOI: 10.1093/brain/awu373  1
2015 Jimenez-Mateos EM, Engel T, Merino-Serrais P, Fernaud-Espinosa I, Rodriguez-Alvarez N, Reynolds J, Reschke CR, Conroy RM, McKiernan RC, deFelipe J, Henshall DC. Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus. Brain Structure & Function. 220: 2387-99. PMID 24874920 DOI: 10.1007/s00429-014-0798-5  1
2015 Spain E, Jimenez-Mateos EM, Raoof R, ElNaggar H, Delanty N, Forster RJ, Henshall DC. Direct, non-amplified detection of microRNA-134 in plasma from epilepsy patients Rsc Advances. 5: 90071-90078. DOI: 10.1039/C5Ra16352H  1
2015 Henshall DC, Engel T. P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus Epilepsy and Behavior. 49: 8-12. DOI: 10.1016/j.yebeh.2015.02.031  1
2015 Jurado-Arjona J, Goñi-Oliver P, Rodríguez-Prada L, Engel T, Henshall DC, Ávila J, Hernández F. Excitotoxicity induced by kainic acid provokes glycogen synthase kinase-3 truncation in the hippocampus Brain Research. 1611: 84-92. DOI: 10.1016/j.brainres.2015.03.016  1
2014 Dunleavy M, Schindler CK, Shinoda S, Crilly S, Henshall DC. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International Journal of Physiology, Pathophysiology and Pharmacology. 6: 199-208. PMID 25755841  1
2014 Dávila D, Jiménez-Mateos EM, Mooney CM, Velasco G, Henshall DC, Prehn JH. Hsp27 binding to the 3'UTR of bim mRNA prevents neuronal death during oxidative stress-induced injury: a novel cytoprotective mechanism. Molecular Biology of the Cell. 25: 3413-23. PMID 25187648 DOI: 10.1091/mbc.E13-08-0495  1
2014 Mesuret G, Engel T, Hessel EV, Sanz-Rodriguez A, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC. P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage Cns Neuroscience and Therapeutics. 20: 556-564. PMID 24750893 DOI: 10.1111/cns.12272  1
2014 Nolan K, Mitchem MR, Jimenez-Mateos EM, Henshall DC, Concannon CG, Prehn JH. Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition. Journal of Molecular Neuroscience : Mn. 53: 231-41. PMID 24696165 DOI: 10.1007/s12031-014-0290-y  1
2014 Henshall DC. MicroRNA and epilepsy: profiling, functions and potential clinical applications. Current Opinion in Neurology. 27: 199-205. PMID 24553459 DOI: 10.1097/WCO.0000000000000079  0.01
2013 Henshall DC, Diaz-Hernandez M, Miras-Portugal MT, Engel T. P2X receptors as targets for the treatment of status epilepticus. Frontiers in Cellular Neuroscience. 7: 237. PMID 24324404 DOI: 10.3389/fncel.2013.00237  1
2013 Henshall DC. MicroRNAs in the pathophysiology and treatment of status epilepticus. Frontiers in Molecular Neuroscience. 6: 37. PMID 24282394 DOI: 10.3389/fnmol.2013.00037  0.01
2013 Henshall DC. Antagomirs and microRNA in status epilepticus. Epilepsia. 54: 17-9. PMID 24001063 DOI: 10.1111/epi.12267  0.01
2013 Miller-Delaney SF, Das S, Stallings RL, Henshall DC. Investigating gene promoter methylation in a mouse model of status epilepticus. Methods in Molecular Biology (Clifton, N.J.). 1067: 87-101. PMID 23975788 DOI: 10.1007/978-1-62703-607-8_7  1
2013 Henshall DC, Engel T. Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts. Frontiers in Cellular Neuroscience. 7: 110. PMID 23882182 DOI: 10.3389/fncel.2013.00110  1
2013 Jimenez-Pacheco A, Mesuret G, Sanz-Rodriguez A, Tanaka K, Mooney C, Conroy R, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC, Engel T. Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079 Epilepsia. 54: 1551-1561. PMID 23808395 DOI: 10.1111/epi.12257  1
2013 Moran C, Sanz-Rodriguez A, Jimenez-Pacheco A, Martinez-Villareal J, McKiernan RC, Jimenez-Mateos EM, Mooney C, Woods I, Prehn JHM, Henshall DC, Engel T. Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death Cell Death and Disease. 4. PMID 23618904 DOI: 10.1038/cddis.2013.136  1
2013 Torres-Peraza JF, Engel T, Martín-Ibáñez R, Sanz-Rodríguez A, Fernández-Fernández MR, Esgleas M, Canals JM, Henshall DC, Lucas JJ. Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus. Brain : a Journal of Neurology. 136: 1161-76. PMID 23518711 DOI: 10.1093/Brain/Awt044  1
2013 Jimenez-Mateos EM, Henshall DC. Epilepsy and microRNA. Neuroscience. 238: 218-29. PMID 23485811 DOI: 10.1016/j.neuroscience.2013.02.027  0.01
2013 Engel T, Sanz-Rodgriguez A, Jimenez-Mateos EM, Concannon CG, Jimenez-Pacheco A, Moran C, Mesuret G, Petit E, Delanty N, Farrell MA, O'Brien DF, Prehn JH, Lucas JJ, Henshall DC. CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain : a Journal of Neurology. 136: 577-92. PMID 23361066 DOI: 10.1093/brain/aws337  1
2013 Brennan GP, Jimenez-Mateos EM, McKiernan RC, Engel T, Tzivion G, Henshall DC. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. Plos One. 8: e54491. PMID 23359526 DOI: 10.1371/Journal.Pone.0054491  1
2013 Caballero-Caballero A, Engel T, Martinez-Villarreal J, Sanz-Rodriguez A, Chang P, Dunleavy M, Mooney CM, Jimenez-Mateos EM, Schindler CK, Henshall DC. Mitochondrial localization of the forkhead box class O transcription factor FOXO3a in brain. Journal of Neurochemistry. 124: 749-56. PMID 23278239 DOI: 10.1111/jnc.12133  1
2013 Dunleavy M, Provenzano G, Henshall DC, Bozzi Y. Kainic acid-induced seizures modulate Akt (SER473) phosphorylation in the hippocampus of dopamine D2 receptor knockout mice. Journal of Molecular Neuroscience : Mn. 49: 202-10. PMID 23188702 DOI: 10.1007/s12031-012-9927-x  1
2013 Michalak Z, Sano T, Engel T, Miller-Delaney SFC, Lerner-Natoli M, Henshall DC. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice Epilepsy Research. 103: 167-179. PMID 23182415 DOI: 10.1016/j.eplepsyres.2012.10.006  1
2013 Henshall DC, Diaz-Hernandez M, Miras-Portugal MT, Engel T. P2X receptors as targets for the treatment of status epilepticus Frontiers in Cellular Neuroscience. 7. DOI: 10.3389/fncel.2013.00237  1
2013 Henshall DC, Engel T. Contribution of apoptosis-associated signaling pathways to epileptogenesis: Lessons from Bcl-2 family knockouts Frontiers in Cellular Neuroscience. DOI: 10.3389/fncel.2013.00110  1
2012 Engel T, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC. P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. International Journal of Physiology, Pathophysiology and Pharmacology. 4: 174-87. PMID 23320131  1
2012 Heverin M, Engel T, Meaney S, Jimenez-Mateos EM, Al-Saudi R, Henshall DC. Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice. Brain Research. 1480: 81-90. PMID 22921849 DOI: 10.1016/j.brainres.2012.08.018  1
2012 Michalak Z, Lebrun A, Di Miceli M, Rousset MC, Crespel A, Coubes P, Henshall DC, Lerner-Natoli M, Rigau V. IgG leakage may contribute to neuronal dysfunction in drug-refractory epilepsies with blood-brain barrier disruption. Journal of Neuropathology and Experimental Neurology. 71: 826-38. PMID 22878666 DOI: 10.1097/NEN.0b013e31826809a6  1
2012 Heverin M, Brennan GP, Koehler CJ, Treumann A, Henshall DC. Proteomic analysis of 14-3-3 zeta binding proteins in the mouse hippocampus. International Journal of Physiology, Pathophysiology and Pharmacology. 4: 74-83. PMID 22837806  1
2012 McKiernan RC, Jimenez-Mateos EM, Sano T, Bray I, Stallings RL, Simon RP, Henshall DC. Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Experimental Neurology. 237: 346-54. PMID 22771761 DOI: 10.1016/j.expneurol.2012.06.029  1
2012 Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, ... ... Henshall DC, et al. Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nature Medicine. 18: 1087-94. PMID 22683779 DOI: 10.1038/nm.2834  1
2012 McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, Michalak Z, Moran C, Delanty N, Farrell M, O'Brien D, Meller R, Simon RP, Stallings RL, Henshall DC. Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. Plos One. 7: e35921. PMID 22615744 DOI: 10.1371/journal.pone.0035921  1
2012 Sano T, Reynolds JP, Jimenez-Mateos EM, Matsushima S, Taki W, Henshall DC. MicroRNA-34a upregulation during seizure-induced neuronal death. Cell Death & Disease. 3: e287. PMID 22436728 DOI: 10.1038/cddis.2012.23  1
2012 Kilany A, Raouf ERA, Gaber AA, Aloush TK, Aref HA, Anwar M, Henshall DC, Abdulghani MO. Elevated serum Bcl-2 in children with temporal lobe epilepsy Seizure. 21: 250-253. PMID 22365585 DOI: 10.1016/j.seizure.2012.01.004  1
2012 Miller-Delaney SF, Das S, Sano T, Jimenez-Mateos EM, Bryan K, Buckley PG, Stallings RL, Henshall DC. Differential DNA methylation patterns define status epilepticus and epileptic tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1577-88. PMID 22302800 DOI: 10.1523/JNEUROSCI.5180-11.2012  1
2012 Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M. Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1616-28. PMID 22198387 DOI: 10.1096/fj.11-196089  1
2012 Simon RP, Meller R, Zhou A, Henshall D. Can genes modify stroke outcome and by what mechanisms? Stroke. 43: 286-91. PMID 22156698 DOI: 10.1161/Strokeaha.111.622225  1
2011 Rünker AE, O'Tuathaigh C, Dunleavy M, Morris DW, Little GE, Corvin AP, Gill M, Henshall DC, Waddington JL, Mitchell KJ. Mutation of Semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology. Plos One. 6: e26488. PMID 22132072 DOI: 10.1371/Journal.Pone.0026488  1
2011 Jimenez-Mateos EM, Bray I, Sanz-Rodriguez A, Engel T, McKiernan RC, Mouri G, Tanaka K, Sano T, Saugstad JA, Simon RP, Stallings RL, Henshall DC. miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. The American Journal of Pathology. 179: 2519-32. PMID 21945804 DOI: 10.1016/j.ajpath.2011.07.036  1
2011 Bozzi Y, Dunleavy M, Henshall DC. Cell signaling underlying epileptic behavior. Frontiers in Behavioral Neuroscience. 5: 45. PMID 21852968 DOI: 10.3389/fnbeh.2011.00045  1
2011 Thompson SJ, Ashley MD, Stöhr S, Schindler C, Li M, McCarthy-Culpepper KA, Pearson AN, Xiong ZG, Simon RP, Henshall DC, Meller R. Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 120-32. PMID 21760970  1
2011 Gangarossa G, Di Benedetto M, O'Sullivan GJ, Dunleavy M, Alcacer C, Bonito-Oliva A, Henshall DC, Waddington JL, Valjent E, Fisone G. Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus. Plos One. 6: e19415. PMID 21559295 DOI: 10.1371/Journal.Pone.0019415  1
2011 Engel T, Schindler CK, Sanz-Rodriguez A, Conroy RM, Meller R, Simon RP, Henshall DC. Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 38-47. PMID 21479101  1
2011 Thompson S, Pearson AN, Ashley MD, Jessick V, Murphy BM, Gafken P, Henshall DC, Morris KT, Simon RP, Meller R. Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection Journal of Biological Chemistry. 286: 19331-19339. PMID 21478148 DOI: 10.1074/Jbc.M110.197707  1
2011 Bunk EC, König HG, Bernas T, Engel T, Henshall DC, Kirby BP, Prehn JH. BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus. Cell Death & Disease. 1: e15. PMID 21364616 DOI: 10.1038/cddis.2009.13  0.01
2011 Engel T, Plesnila N, Prehn JH, Henshall DC. In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1196-210. PMID 21364604 DOI: 10.1038/jcbfm.2011.26  1
2011 Tsuchiya T, Bonner HP, Engel T, Woods I, Matsushima S, Ward MW, Taki W, Henshall DC, Concannon CG, Prehn JH. Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo. The European Journal of Neuroscience. 33: 401-8. PMID 21198986 DOI: 10.1111/j.1460-9568.2010.07538.x  1
2010 Engel T, Tanaka K, Jimenez-Mateos EM, Caballero-Caballero A, Prehn JH, Henshall DC. Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus. Cell Death & Disease. 1: e79. PMID 21368852 DOI: 10.1038/cddis.2010.55  0.01
2010 Jimenez-Mateos EM, Mouri G, Conroy RM, Henshall DC. Epileptic tolerance is associated with enduring neuroprotection and uncoupling of the relationship between CA3 damage, neuropeptide Y rearrangement and spontaneous seizures following intra-amygdala kainic acid-induced status epilepticus in mice. Neuroscience. 171: 556-65. PMID 20837105 DOI: 10.1016/j.neuroscience.2010.09.003  0.01
2010 Engel T, Caballero-Caballero A, Schindler CK, Plesnila N, Strasser A, Prehn JH, Henshall DC. BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor. Journal of Neurochemistry. 115: 92-101. PMID 20646170 DOI: 10.1111/j.1471-4159.2010.06909.x  1
2010 Engel T, Hatazaki S, Tanaka K, Prehn JH, Henshall DC. Deletion of Puma protects hippocampal neurons in a model of severe status epilepticus. Neuroscience. 168: 443-50. PMID 20362645 DOI: 10.1016/j.neuroscience.2010.03.057  0.01
2010 Dunleavy M, Shinoda S, Schindler C, Ewart C, Dolan R, Gobbo OL, Kerskens CM, Henshall DC. Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis. The American Journal of Pathology. 176: 330-42. PMID 19948825 DOI: 10.2353/ajpath.2010.090119  1
2010 Tanaka K, Jimenez-Mateos EM, Matsushima S, Taki W, Henshall DC. Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice. Epilepsy Research. 88: 151-61. PMID 19931419 DOI: 10.1016/j.eplepsyres.2009.10.012  1
2010 Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 853-61. PMID 19890018 DOI: 10.1096/fj.09-145870  1
2010 Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, ... Henshall DC, et al. Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus. Cell Death and Differentiation. 17: 459-68. PMID 19779495 DOI: 10.1038/Cdd.2009.134  1
2010 Henshall DC, Meldrum BS. Cell death after single and repeated brief seizures Epilepsia. 51: 35. DOI: 10.1111/j.1528-1167.2010.02821.x  1
2009 Jimenez-Mateos EM, Henshall DC. Seizure preconditioning and epileptic tolerance: models and mechanisms. International Journal of Physiology, Pathophysiology and Pharmacology. 1: 180-191. PMID 21383886  1
2009 Engel T, Henshall DC. Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? International Journal of Physiology, Pathophysiology and Pharmacology. 1: 97-115. PMID 21383882  1
2009 Henshall DC, Dürmüller N, White HS, Williams R, Moser P, Dunleavy M, Silverstone PH. Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents. Neuropsychiatric Disease and Treatment. 5: 189-206. PMID 19557114 DOI: 10.2147/Ndt.S4714  1
2009 Kuroki K, Virard I, Concannon CG, Engel T, Woods I, Taki W, Plesnila N, Henshall DC, Prehn JH. Effects of transient focal cerebral ischemia in mice deficient in puma. Neuroscience Letters. 451: 237-40. PMID 19159665 DOI: 10.1016/j.neulet.2009.01.019  1
2008 Jimenez-Mateos EM, Hatazaki S, Johnson MB, Bellver-Estelles C, Mouri G, Bonner C, Prehn JH, Meller R, Simon RP, Henshall DC. Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiology of Disease. 32: 442-53. PMID 18804535 DOI: 10.1016/j.nbd.2008.08.008  1
2008 Murphy N, Yamamoto A, Henshall DC. Detection of 14-3-3zeta in cerebrospinal fluid following experimentally evoked seizures. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 13: 377-84. PMID 18484353 DOI: 10.1080/13547500802027971   1
2008 Murphy N, Bonner HP, Ward MW, Murphy BM, Prehn JH, Henshall DC. Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures. Journal of Neurochemistry. 106: 978-88. PMID 18466333 DOI: 10.1111/j.1471-4159.2008.05447.x  1
2008 Mouri G, Jimenez-Mateos E, Engel T, Dunleavy M, Hatazaki S, Paucard A, Matsushima S, Taki W, Henshall DC. Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Research. 1213: 140-51. PMID 18455706 DOI: 10.1016/j.brainres.2008.03.061  1
2008 O'Sullivan GJ, Dunleavy M, Hakansson K, Clementi M, Kinsella A, Croke DT, Drago J, Fienberg AA, Greengard P, Sibley DR, Fisone G, Henshall DC, Waddington JL. Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling. Neuropharmacology. 54: 1051-61. PMID 18367215 DOI: 10.1016/J.Neuropharm.2008.02.011  1
2008 Meller R, Thompson SJ, Lusardi TA, Ordonez AN, Ashley MD, Jessick V, Wang W, Torrey DJ, Henshall DC, Gafken PR, Saugstad JA, Xiong ZG, Simon RP. Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 50-9. PMID 18171922 DOI: 10.1523/Jneurosci.3474-07.2008  1
2008 Concannon CG, Ward MW, Bonner HP, Kuroki K, Tuffy LP, Bonner CT, Woods I, Engel T, Henshall DC, Prehn JH. NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. Journal of Neurochemistry. 105: 891-903. PMID 18088354 DOI: 10.1111/J.1471-4159.2007.05187.X  1
2008 Mitchell K, Runker A, Little G, O'Tuathaigh C, Dunleavy M, Morris D, Corvin A, Gill M, Henshall D, Waddington J. Semaphorin And Plexin Genes Specify Limbic And Cortical Connectivity And Are Implicated In The Etiology Of Schizophrenia Schizophrenia Research. 102: 26-27. DOI: 10.1016/S0920-9964(08)70084-7  1
2007 Simon R, Henshall D, Stoehr S, Meller R. Endogenous mechanisms of neuroprotection. Epilepsia. 48: 72-73. PMID 18330006 DOI: 10.1111/J.1528-1167.2007.01356.X  1
2007 Engel T, Murphy BM, Schindler CK, Henshall DC. Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy Research. 77: 151-6. PMID 17942278 DOI: 10.1016/j.eplepsyres.2007.09.001  0.01
2007 Hatazaki S, Bellver-Estelles C, Jimenez-Mateos EM, Meller R, Bonner C, Murphy N, Matsushima S, Taki W, Prehn JH, Simon RP, Henshall DC. Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning. Neuroscience. 150: 467-77. PMID 17935890 DOI: 10.1016/j.neuroscience.2007.09.020  1
2007 Henshall DC, Murphy BM. Modulators of neuronal cell death in epilepsy. Current Opinion in Pharmacology. 8: 75-81. PMID 17827063 DOI: 10.1016/J.COPH.2007.07.005  0.01
2007 Murphy B, Dunleavy M, Shinoda S, Schindler C, Meller R, Bellver-Estelles C, Hatazaki S, Dicker P, Yamamoto A, Koegel I, Chu X, Wang W, Xiong Z, Prehn J, Simon R, ... Henshall D, et al. Bcl-w protects hippocampus during experimental status epilepticus. The American Journal of Pathology. 171: 1258-68. PMID 17702891 DOI: 10.2353/Ajpath.2007.070269  1
2007 Henshall DC. Apoptosis signalling pathways in seizure-induced neuronal death and epilepsy. Biochemical Society Transactions. 35: 421-3. PMID 17371290 DOI: 10.1042/BST0350421  0.01
2007 Rosenzweig HL, Minami M, Lessov NS, Coste SC, Stevens SL, Henshall DC, Meller R, Simon RP, Stenzel-Poore MP. Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1663-74. PMID 17327883 DOI: 10.1038/sj.jcbfm.9600464  1
2006 Schindler CK, Heverin M, Henshall DC. Isoform- and subcellular fraction-specific differences in hippocampal 14-3-3 levels following experimentally evoked seizures and in human temporal lobe epilepsy. Journal of Neurochemistry. 99: 561-9. PMID 16981892 DOI: 10.1111/j.1471-4159.2006.04153.x  0.01
2006 Yamamoto A, Schindler CK, Murphy BM, Bellver-Estelles C, So NK, Taki W, Meller R, Simon RP, Henshall DC. Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy. Experimental Neurology. 202: 410-20. PMID 16919273 DOI: 10.1016/j.expneurol.2006.07.003  1
2006 Yamamoto A, Murphy N, Schindler CK, So NK, Stohr S, Taki W, Prehn JH, Henshall DC. Endoplasmic reticulum stress and apoptosis signaling in human temporal lobe epilepsy. Journal of Neuropathology and Experimental Neurology. 65: 217-25. PMID 16651883 DOI: 10.1097/01.jnen.0000202886.22082.2a  1
2006 Meller R, Clayton C, Torrey DJ, Schindler CK, Lan JQ, Cameron JA, Chu XP, Xiong ZG, Simon RP, Henshall DC. Activation of the caspase 8 pathway mediates seizure-induced cell death in cultured hippocampal neurons. Epilepsy Research. 70: 3-14. PMID 16542823 DOI: 10.1016/j.eplepsyres.2006.02.002  1
2006 Meller R, Cameron JA, Torrey DJ, Clayton CE, Ordonez AN, Henshall DC, Minami M, Schindler CK, Saugstad JA, Simon RP. Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. The Journal of Biological Chemistry. 281: 7429-36. PMID 16431916 DOI: 10.1074/jbc.M512138200  1
2006 Schindler CK, Pearson EG, Bonner HP, So NK, Simon RP, Prehn JH, Henshall DC. Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 583-9. PMID 16121124 DOI: 10.1038/sj.jcbfm.9600219  1
2006 Henshall DC, Simon RP. Epilepsy and apoptosis pathways. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1557-72. PMID 15889042 DOI: 10.1038/sj.jcbfm.9600149  0.01
2005 Meller R, Minami M, Cameron JA, Impey S, Chen D, Lan JQ, Henshall DC, Simon RP. CREB-mediated Bcl-2 protein expression after ischemic preconditioning. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 234-46. PMID 15647742 DOI: 10.1038/sj.jcbfm.9600024  1
2004 Rosenzweig HL, Lessov NS, Henshall DC, Minami M, Simon RP, Stenzel-Poore MP. Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke; a Journal of Cerebral Circulation. 35: 2576-81. PMID 15375302 DOI: 10.1161/01.STR.0000143450.04438.ae  1
2004 Araki T, Shinoda S, Schindler CK, Quan-Lan J, Meller R, Taki W, Simon RP, Henshall DC. Expression, interaction, and proteolysis of death-associated protein kinase and p53 within vulnerable and resistant hippocampal subfields following seizures. Hippocampus. 14: 326-36. PMID 15132432 DOI: 10.1002/HIPO.10184  0.01
2004 Shinoda S, Schindler CK, Meller R, So NK, Araki T, Yamamoto A, Lan JQ, Taki W, Simon RP, Henshall DC. Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. The Journal of Clinical Investigation. 113: 1059-68. PMID 15057313 DOI: 10.1172/JCI19971  1
2004 Shinoda S, Araki T, Lan JQ, Schindler CK, Simon RP, Taki W, Henshall DC. Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse. Journal of Neuroscience Research. 76: 121-8. PMID 15048936 DOI: 10.1002/jnr.20064  0.01
2004 Henshall DC, Schindler CK, So NK, Lan JQ, Meller R, Simon RP. Death-associated protein kinase expression in human temporal lobe epilepsy. Annals of Neurology. 55: 485-94. PMID 15048887 DOI: 10.1002/ana.20001  1
2004 Schindler CK, Shinoda S, Simon RP, Henshall DC. Subcellular distribution of Bcl-2 family proteins and 14-3-3 within the hippocampus during seizure-induced neuronal death in the rat. Neuroscience Letters. 356: 163-6. PMID 15036620 DOI: 10.1016/j.neulet.2003.11.048  0.01
2003 Jin K, Peel AL, Mao XO, Xie L, Cottrell BA, Henshall DC, Greenberg DA. Increased hippocampal neurogenesis in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 343-7. PMID 14660786 DOI: 10.1073/pnas.2634794100  0.01
2003 Henshall DC, Araki T, Schindler CK, Shinoda S, Lan JQ, Simon RP. Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures. Journal of Neurochemistry. 86: 1260-70. PMID 12911633 DOI: 10.1046/j.1471-4159.2003.01934.x  0.01
2003 Shinoda S, Schindler CK, Quan-Lan J, Saugstad JA, Taki W, Simon RP, Henshall DC. Interaction of 14-3-3 with Bid during seizure-induced neuronal death. Journal of Neurochemistry. 86: 460-9. PMID 12871587 DOI: 10.1046/j.1471-4159.2003.01860.x  0.01
2003 Shinoda S, Skradski SL, Araki T, Schindler CK, Meller R, Lan JQ, Taki W, Simon RP, Henshall DC. Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. The European Journal of Neuroscience. 17: 2065-76. PMID 12786973 DOI: 10.1046/J.1460-9568.2003.02655.X  1
2003 Meller R, Schindler CK, Chu XP, Xiong ZG, Cameron JA, Simon RP, Henshall DC. Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. Cell Death and Differentiation. 10: 539-47. PMID 12728252 DOI: 10.1038/sj.cdd.4401206  1
2003 Liou AK, Clark RS, Henshall DC, Yin XM, Chen J. To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Progress in Neurobiology. 69: 103-42. PMID 12684068 DOI: 10.1016/S0301-0082(03)00005-4  1
2003 Chen D, Minami M, Henshall DC, Meller R, Kisby G, Simon RP. Upregulation of mitochondrial base-excision repair capability within rat brain after brief ischemia. Journal of Cerebral Blood Flow and Metabolism. 23: 88-98. PMID 12500094 DOI: 10.1097/01.Wcb.0000039286.37737.19  1
2002 Araki T, Simon RP, Taki W, Lan JQ, Henshall DC. Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. Journal of Neuroscience Research. 69: 614-21. PMID 12210827 DOI: 10.1002/jnr.10356  0.01
2002 Henshall DC, Skradski SL, Meller R, Araki T, Minami M, Schindler CK, Lan JQ, Bonislawski DP, Simon RP. Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. Neurobiology of Disease. 10: 71-87. PMID 12127146 DOI: 10.1006/Nbdi.2002.0505  1
2002 Meller R, Skradski SL, Simon RP, Henshall DC. Expression, proteolysis and activation of caspases 6 and 7 during rat C6 glioma cell apoptosis. Neuroscience Letters. 324: 33-6. PMID 11983288 DOI: 10.1016/S0304-3940(02)00166-0  1
2002 Henshall D, Sinclair J, Simon R. Relationship between seizure-induced transcription of the DNA damage-inducible gene GADD45, DNA fragmentation, and neuronal death in focally evoked limbic epilepsy. Journal of Neurochemistry. 73: 1573-1583. PMID 10501203 DOI: 10.1046/J.1471-4159.1999.0731573.X  1
2002 Henshall DC, Araki T, Schindler CK, Lan J, Tiekoter KL, Taki W, Simon RP. Activation of Bcl-2-Associated Death Protein and Counter-Response of Akt within Cell Populations during Seizure-Induced Neuronal Death The Journal of Neuroscience. 22: 8458-8465. DOI: 10.1523/JNEUROSCI.22-19-08458.2002  0.01
2001 Henshall DC, Bonislawski DP, Skradski SL, Araki T, Lan JQ, Schindler CK, Meller R, Simon RP. Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death Cell Death and Differentiation. 8: 1169-1181. PMID 11753565 DOI: 10.1038/sj.cdd.4400921  1
2001 Henshall DC, Bonislawski DP, Skradski SL, Lan JQ, Meller R, Simon RP. Cleavage of Bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures Neurobiology of Disease. 8: 568-580. PMID 11493022 DOI: 10.1006/Nbdi.2001.0415  1
2001 Henshall DC, Skradski SL, Lan JQ, Ren T, Simon RP. Increased Bcl-w expression following focally evoked limbic seizures in the rat Neuroscience Letters. 305: 153-156. PMID 11403928 DOI: 10.1016/S0304-3940(01)01849-3  1
2001 Henshall DC, Skradski SL, Bonislawski DP, Lan JQ, Simon RP. Caspase-2 activation is redundant during seizure-induced neuronal death Journal of Neurochemistry. 77: 886-895. PMID 11331417 DOI: 10.1046/J.1471-4159.2001.00291.X  1
2000 Nagayama T, Lan J, Henshall DC, Chen D, O'Horo C, Simon RP, Chen J. Induction of oxidative DNA damage in the peri-infarct region after permanent focal cerebral ischemia. Journal of Neurochemistry. 75: 1716-28. PMID 10987855 DOI: 10.1046/J.1471-4159.2000.0751716.X  1
2000 Henshall DC, Clark RS, Adelson PD, Chen M, Watkins SC, Simon RP. Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy. Neurology. 55: 250-7. PMID 10908900 DOI: 10.1212/WNL.55.2.250  1
2000 Nagayama T, Simon RP, Chen D, Henshall DC, Pei W, Stetler RA, Chen J. Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia. Journal of Neurochemistry. 74: 1636-45. PMID 10737622 DOI: 10.1046/J.1471-4159.2000.0741636.X  1
2000 Henshall DC, Sinclair J, Simon RP. Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures. Brain Research. 858: 290-302. PMID 10708680 DOI: 10.1016/S0006-8993(99)02452-X  0.01
2000 Henshall DC, Chen J, Simon RP. Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. Journal of Neurochemistry. 74: 1215-23. PMID 10693954 DOI: 10.1046/J.1471-4159.2000.741215.X  0.01
2000 Minami M, Jin KL, Li W, Nagayama T, Henshall DC, Simon RP. Bcl-w expression is increased in brain regions affected by focal cerebral ischemia in the rat. Neuroscience Letters. 279: 193-5. PMID 10688062 DOI: 10.1016/S0304-3940(99)00987-8  1
2000 Lan J, Henshall DC, Simon RP, Chen J. Formation of the base modification 8-hydroxyl-2'-deoxyguanosine and DNA fragmentation following seizures induced by systemic kainic acid in the rat. Journal of Neurochemistry. 74: 302-9. PMID 10617133 DOI: 10.1046/J.1471-4159.2000.0740302.X  0.01
1999 Henshall DC, Butcher SP, Sharkey J. A rat model of endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion. Brain Research. 843: 105-11. PMID 10528116 DOI: 10.1016/S0006-8993(99)01896-X  0.01
1999 Kawaguchi K, Henshall DC, Simon RP. Parallel dose-response studies of the voltage-dependent Na+ channel antagonist BW619C89, and the voltage-dependent Ca2+ channel antagonist nimodipine, in rat transient focal cerebral ischaemia. European Journal of Pharmacology. 364: 99-105. PMID 9932711 DOI: 10.1016/S0014-2999(98)00827-9  0.01
1998 Tanaka K, Henshall DC, Waga S, Shimosaka S, Simon RP. Bilateral intranigral NMDA infusion suppresses neuronal injury without affecting the duration of kainic acid-induced seizures in rats. Neuroscience Letters. 251: 69-71. PMID 9714467 DOI: 10.1016/S0304-3940(98)00483-2  0.01
1997 Butcher SP, Henshall DC, Teramura Y, Iwasaki K, Sharkey J. Neuroprotective Actions of FK506 in Experimental Stroke:In VivoEvidence against an Antiexcitotoxic Mechanism The Journal of Neuroscience. 17: 6939-6946. DOI: 10.1523/JNEUROSCI.17-18-06939.1997  0.01
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