| Year |
Citation |
Score |
| 2023 |
Steinruecke M, Gillespie C, Ahmed N, Bandyopadhyay S, Duklas D, Ghahfarokhi MH, Henshall DE, Khan M, de Koning R, Madden J, Marston JSN, Mohamed RAA, Nischal SA, Norton EJ, Parameswaran G, et al. Care and three-year outcomes of children with Benign Epilepsy with Centro-Temporal Spikes in England. Epilepsy & Behavior : E&B. 148: 109465. PMID 37844441 DOI: 10.1016/j.yebeh.2023.109465 |
0.322 |
|
| 2023 |
Brindley E, Heiland M, Mooney C, Diviney M, Mamad O, Hill TDM, Yan Y, Venø MT, Reschke CR, Batool A, Langa E, Sanz-Rodriguez A, Heller JP, Morris G, Conboy K, ... ... Henshall DC, et al. Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy. Frontiers in Molecular Neuroscience. 16: 1230942. PMID 37808470 DOI: 10.3389/fnmol.2023.1230942 |
0.706 |
|
| 2023 |
de Diego-Garcia L, Brennan GP, Auer T, Menendez-Mendez A, Parras A, Martin-Gil A, Mitra M, Ollà I, Villalba-Benito L, Gil B, Alves M, Lau K, Delanty N, Beausang A, Cryan J, ... ... Henshall DC, et al. CPEB4 - CLOCK crosstalk during temporal lobe epilepsy. Epilepsia. PMID 37543852 DOI: 10.1111/epi.17736 |
0.408 |
|
| 2023 |
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, ... ... Henshall DC, et al. MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216658120. PMID 37463203 DOI: 10.1073/pnas.2216658120 |
0.724 |
|
| 2023 |
Smith J, Méndez AM, Alves M, Parras A, Conte G, Bhattacharya A, Ceusters M, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following neonatal hypoxia in mice. British Journal of Pharmacology. PMID 36637008 DOI: 10.1111/bph.16033 |
0.414 |
|
| 2022 |
Morgan J, Moreno O, Alves M, Baz Z, Menéndez Méndez A, Leister H, Melia C, Smith J, Visekruna A, Nicke A, Bhattacharya A, Ceusters M, Henshall DC, Gómez-Vallejo V, Llop J, et al. Increased uptake of the P2X7 receptor radiotracer F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Epilepsia. PMID 36507708 DOI: 10.1111/epi.17484 |
0.354 |
|
| 2022 |
Quinlan S, Henke C, Brennan GP, Henshall DC, Jimenez-Mateos EM. Detection of MicroRNAs in Brain Slices Using In Situ Hybridization. Methods in Molecular Biology (Clifton, N.J.). 2595: 93-100. PMID 36441456 DOI: 10.1007/978-1-0716-2823-2_6 |
0.3 |
|
| 2022 |
Gerbatin RR, Augusto J, Morris G, Campbell A, Worm J, Langa E, Reschke CR, Henshall DC. Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome. Eneuro. 9. PMID 36240080 DOI: 10.1523/ENEURO.0112-22.2022 |
0.588 |
|
| 2022 |
Morris G, Langa E, Fearon C, Conboy K, Lau E-How K, Sanz-Rodriguez A, O'Brien DF, Sweeney K, Lacey A, Delanty N, Beausang A, Brett FM, Cryan JB, Cunningham MO, Henshall DC. MicroRNA inhibition using antimiRs in acute human brain tissue sections. Epilepsia. PMID 35656590 DOI: 10.1111/epi.17317 |
0.443 |
|
| 2022 |
Campbell A, Morris G, Sanfeliu A, Augusto J, Langa E, Kesavan JC, Nguyen NT, Conroy RM, Worm J, Kielpinski L, Jensen MA, Miller MT, Kremer T, Reschke CR, Henshall DC. AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome. Molecular Therapy. Nucleic Acids. 28: 514-529. PMID 35592499 DOI: 10.1016/j.omtn.2022.04.009 |
0.49 |
|
| 2022 |
Forster RJ, Henshall DC, El Naggar H, Pellegrin Y, Delanty N. Electrochemiluminescent detection of epilepsy biomarker miR-134 using a metal complex light switch. Bioelectrochemistry (Amsterdam, Netherlands). 146: 108150. PMID 35550256 DOI: 10.1016/j.bioelechem.2022.108150 |
0.426 |
|
| 2022 |
Gerbatin RR, Augusto J, Boutouil H, Reschke CR, Henshall DC. Life-span characterization of epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the Scn1a gene. Experimental Neurology. 354: 114090. PMID 35487274 DOI: 10.1016/j.expneurol.2022.114090 |
0.325 |
|
| 2022 |
Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, ... ... Henshall DC, et al. Microvascular stabilization via blood-brain barrier regulation prevents seizure activity. Nature Communications. 13: 2003. PMID 35422069 DOI: 10.1038/s41467-022-29657-y |
0.428 |
|
| 2022 |
Morris G, Heiland M, Lamottke K, Guan H, Hill TDM, Zhou Y, Zhu Q, Schorge S, Henshall DC. BICS01 Mediates Reversible Anti-seizure Effects in Brain Slice Models of Epilepsy. Frontiers in Neurology. 12: 791608. PMID 35069421 DOI: 10.3389/fneur.2021.791608 |
0.403 |
|
| 2021 |
Conte G, Menéndez-Méndez A, Bauer S, El-Naggar H, Alves M, Nicke A, Delanty N, Rosenow F, Henshall DC, Engel T. Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy. Cells. 10. PMID 34572093 DOI: 10.3390/cells10092444 |
0.426 |
|
| 2021 |
Morris G, O'Brien D, Henshall DC. Opportunities and challenges for microRNA-targeting therapeutics for epilepsy. Trends in Pharmacological Sciences. PMID 33992468 DOI: 10.1016/j.tips.2021.04.007 |
0.516 |
|
| 2021 |
Reschke CR, Silva LFA, Vangoor VR, Rosso M, David B, Cavanagh BL, Connolly NMC, Brennan GP, Sanz-Rodriguez A, Mooney C, Batool A, Greene C, Brennan M, Conroy RM, Rüber T, ... ... Henshall DC, et al. Systemic delivery of antagomirs during blood brain barrier disruption is disease-modifying in experimental epilepsy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33609732 DOI: 10.1016/j.ymthe.2021.02.021 |
0.468 |
|
| 2021 |
Beamer E, Lacey A, Alves M, Conte G, Tian F, de Diego-Garcia L, Khalil M, Rosenow F, Delanty N, Dale N, El-Naggar H, Henshall DC, Engel T. Elevated blood purine levels as a biomarker of seizures and epilepsy. Epilepsia. PMID 33599287 DOI: 10.1111/epi.16839 |
0.422 |
|
| 2021 |
Gomes-Duarte A, Bauer S, Venø MT, Norwood BA, Henshall DC, Kjems J, Rosenow F, Vangoor VR, Pasterkamp RJ. Enrichment of Circular RNA Expression Deregulation at the Transition to Recurrent Spontaneous Seizures in Experimental Temporal Lobe Epilepsy. Frontiers in Genetics. 12: 627907. PMID 33584828 DOI: 10.3389/fgene.2021.627907 |
0.453 |
|
| 2021 |
Wilson MM, Henshall DC, Byrne SM, Brennan GP. CHD2-Related CNS Pathologies. International Journal of Molecular Sciences. 22. PMID 33435571 DOI: 10.3390/ijms22020588 |
0.57 |
|
| 2021 |
Campbell A, Morris G, Heller JP, Langa E, Brindley E, Worm J, Jensen MA, Miller MT, Henshall DC, Reschke CR. Antagomir-mediated suppression of microRNA-134 reduces kainic acid-induced seizures in immature mice. Scientific Reports. 11: 340. PMID 33431894 DOI: 10.1038/s41598-020-79350-7 |
0.726 |
|
| 2020 |
Conte G, Parras A, Alves M, Ollà I, De Diego-Garcia L, Beamer E, Alalqam R, Ocampo A, Mendez R, Henshall DC, Lucas JJ, Engel T. High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsy. Epilepsia. PMID 33070315 DOI: 10.1111/epi.16714 |
0.339 |
|
| 2020 |
Conte G, Nguyen NT, Alves M, de Diego-Garcia L, Kenny A, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice. Frontiers in Molecular Neuroscience. 13: 127. PMID 32982684 DOI: 10.3389/Fnmol.2020.00127 |
0.305 |
|
| 2020 |
Almeida Silva LF, Reschke CR, Nguyen NT, Langa E, Sanz-Rodriguez A, Gerbatin RR, Temp FR, de Freitas ML, Conroy RM, Brennan GP, Engel T, Henshall DC. Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice. Molecular Brain. 13: 114. PMID 32825833 DOI: 10.1186/s13041-020-00653-x |
0.5 |
|
| 2020 |
Brennan GP, Bauer S, Engel T, Jimenez-Mateos EM, Del Gallo F, Hill TDM, Connolly NMC, Costard LS, Neubert V, Salvetti B, Sanz-Rodriguez A, Heiland M, Mamad O, Brindley E, Norwood B, ... ... Henshall DC, et al. Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy. Neurobiology of Disease. 144: 105048. PMID 32800995 DOI: 10.1016/J.Nbd.2020.105048 |
0.731 |
|
| 2020 |
Casey S, Goasdoue K, Miller SM, Brennan GP, Cowin G, O'Mahony AG, Burke C, Hallberg B, Boylan GB, Sullivan AM, Henshall DC, O'Keeffe GW, Mooney C, Bjorkman T, Murray DM. Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury. Molecular Neurobiology. PMID 32720074 DOI: 10.1007/S12035-020-02018-W |
0.445 |
|
| 2020 |
Parras A, de Diego-Garcia L, Alves M, Beamer E, Conte G, Jimenez-Mateos EM, Morgan J, Ollà I, Hernandez-Santana Y, Delanty N, Farrell MA, O'Brien DF, Ocampo A, Henshall DC, Méndez R, et al. Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy. Brain : a Journal of Neurology. PMID 32594159 DOI: 10.1093/brain/awaa168 |
0.416 |
|
| 2020 |
Venø MT, Reschke CR, Morris G, Connolly NMC, Su J, Yan Y, Engel T, Jimenez-Mateos EM, Harder LM, Pultz D, Haunsberger SJ, Pal A, Heller JP, Campbell A, Langa E, ... ... Henshall DC, et al. A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32581127 DOI: 10.1073/Pnas.1919313117 |
0.751 |
|
| 2020 |
Brennan GP, Henshall DC. MicroRNAs as regulators of brain function and targets for treatment of epilepsy. Nature Reviews. Neurology. PMID 32546757 DOI: 10.1038/s41582-020-0369-8 |
0.488 |
|
| 2020 |
Kobow K, Reid CA, van Vliet EA, Becker AJ, Carvill GL, Goldman AM, Hirose S, Lopes-Cendes I, Khiari HM, Poduri A, Johnson MR, Henshall DC. Epigenetics explained: a topic "primer" for the epilepsy community by the ILAE Genetics/Epigenetics Task Force. Epileptic Disorders : International Epilepsy Journal With Videotape. PMID 32301721 DOI: 10.1684/epd.2020.1143 |
0.306 |
|
| 2020 |
Mooney C, McKiernan PJ, Raoof R, Henshall DC, Linnane B, McNally P, Glasgow AMA, Greene CM. Plasma microRNA levels in male and female children with cystic fibrosis. Scientific Reports. 10: 1141. PMID 31980676 DOI: 10.1038/S41598-020-57964-1 |
0.426 |
|
| 2020 |
Traynelis SF, Dlugos D, Henshall D, Mefford HC, Rogawski MA, Staley KJ, Dacks PA, Whittemore V, Poduri A. 2020 Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects. Epilepsy Currents. 1535759719895279. PMID 31965829 DOI: 10.1177/1535759719895279 |
0.397 |
|
| 2019 |
Batool A, Hill TDM, Nguyen NT, Langa E, Diviney M, Mooney C, Brennan GP, Connolly NMC, Sanz-Rodriguez A, Cavanagh BL, Henshall DC. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in Neuroscience. 13: 1404. PMID 32009885 DOI: 10.3389/fnins.2019.01404 |
0.444 |
|
| 2019 |
Henshall DC. Brain delivery of a virus to block seizures helps mice get a silent NACHT. Ebiomedicine. PMID 31474550 DOI: 10.1016/j.ebiom.2019.08.066 |
0.333 |
|
| 2019 |
Quinlan S, Merino-Serrais P, Di Grande A, Dussmann H, Prehn JHM, Ní Chonghaile T, Henshall DC, Jimenez-Mateos EM. The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia. Frontiers in Immunology. 10: 1752. PMID 31396238 DOI: 10.3389/fimmu.2019.01752 |
0.399 |
|
| 2019 |
Morris G, Reschke CR, Henshall DC. Targeting microRNA-134 for seizure control and disease modification in epilepsy. Ebiomedicine. PMID 31300345 DOI: 10.1016/J.Ebiom.2019.07.008 |
0.577 |
|
| 2019 |
Costard LS, Neubert V, Venø MT, Su J, Kjems J, Connolly NMC, Prehn JHM, Schratt G, Henshall DC, Rosenow F, Bauer S. Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression. Brain Stimulation. PMID 31208877 DOI: 10.1016/J.Brs.2019.06.009 |
0.364 |
|
| 2019 |
Brindley E, Hill TDM, Henshall DC. MicroRNAs as biomarkers and treatment targets in status epilepticus. Epilepsy & Behavior : E&B. PMID 31171435 DOI: 10.1016/j.yebeh.2019.04.025 |
0.509 |
|
| 2019 |
Alves M, De Diego Garcia L, Conte G, Jimenez-Mateos EM, D'Orsi B, Sanz-Rodriguez A, Prehn JH, Henshall DC, Engel T. Context-specific switch from anti- to pro-epileptogenic function of the P2Y receptor in experimental epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31048325 DOI: 10.1523/JNEUROSCI.0089-19.2019 |
0.424 |
|
| 2019 |
Hogg MC, Raoof R, El Naggar H, Monsefi N, Delanty N, O'Brien DF, Bauer S, Rosenow F, Henshall DC, Prehn JH. Elevation in plasma tRNA fragments precede seizures in human epilepsy. The Journal of Clinical Investigation. 130. PMID 31039137 DOI: 10.1172/JCI126346 |
0.42 |
|
| 2019 |
Vangoor VR, Reschke CR, Senthilkumar K, van de Haar LL, de Wit M, Giuliani G, Broekhoven MH, Morris G, Engel T, Brennan GP, Conroy RM, van Rijen PC, Gosselaar PH, Schorge S, Schaapveld RQJ, ... Henshall DC, et al. Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31015341 DOI: 10.1523/Jneurosci.3014-18.2019 |
0.608 |
|
| 2019 |
Morris G, Veno M, Reschke C, Bauer S, Yan Y, Engel T, Pasterkamp RJ, Prehn JH, Schorge S, Rosenow F, Kjems J, Henshall DC. Argonaute-2 sequencing of rodent status epilepticus models identifies multiple microRNA targets for seizure suppression Epilepsy & Behavior. 101: 106737. DOI: 10.1016/J.Yebeh.2019.08.012 |
0.448 |
|
| 2018 |
Kenny A, Hernández F, Avila J, Lucas JJ, Henshall DC, Prehn JH, Jiménez-Mateos EM, Engel T. Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17. International Journal of Physiology, Pathophysiology and Pharmacology. 10: 172-183. PMID 30697364 |
0.358 |
|
| 2018 |
Beamer EH, Jurado-Arjona J, Jimenez-Mateos EM, Morgan J, Reschke CR, Kenny A, de Leo G, Olivos-Oré LA, Arribas-Blázquez M, Madden SF, Merchán-Rubira J, Delanty N, Farrell MA, O'Brien DF, Avila J, ... ... Henshall DC, et al. MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus. Frontiers in Molecular Neuroscience. 11: 442. PMID 30618601 DOI: 10.3389/fnmol.2018.00442 |
0.329 |
|
| 2018 |
Enright N, Simonato M, Henshall DC. Discovery and validation of blood microRNAs as molecular biomarkers of epilepsy: Ways to close current knowledge gaps. Epilepsia Open. 3: 427-436. PMID 30525113 DOI: 10.1002/epi4.12275 |
0.504 |
|
| 2018 |
Brennan GP, Vitsios DM, Casey S, Looney AM, Hallberg B, Henshall DC, Boylan GB, Murray DM, Mooney C. RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns. Plos One. 13: e0207952. PMID 30507953 DOI: 10.1371/journal.pone.0207952 |
0.417 |
|
| 2018 |
Raoof R, Bauer S, El Naggar H, Connolly NMC, Brennan GP, Brindley E, Hill T, McArdle H, Spain E, Forster RJ, Prehn JHM, Hamer H, Delanty N, Rosenow F, Mooney C, ... Henshall DC, et al. Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy. Ebiomedicine. PMID 30396857 DOI: 10.1016/J.Ebiom.2018.10.068 |
0.446 |
|
| 2018 |
Engel T, Gómez-Sintes R, Alves M, Jimenez-Mateos EM, Fernández-Nogales M, Sanz-Rodriguez A, Morgan J, Beamer E, Rodríguez-Matellán A, Dunleavy M, Sano T, Avila J, Medina M, Hernandez F, Lucas JJ, ... Henshall DC, et al. Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus. Cell Death & Disease. 9: 969. PMID 30237424 DOI: 10.1038/s41419-018-0963-5 |
0.351 |
|
| 2018 |
Morris G, Brennan GP, Reschke CR, Henshall DC, Schorge S. Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA-134. Epilepsia. PMID 29978460 DOI: 10.1111/Epi.14475 |
0.346 |
|
| 2018 |
Quinlan SMM, Rodriguez-Alvarez N, Molloy EJ, Madden SF, Boylan GB, Henshall DC, Jimenez-Mateos EM. Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures. Scientific Reports. 8: 9986. PMID 29968748 DOI: 10.1038/s41598-018-28044-2 |
0.43 |
|
| 2018 |
Sebastián-Serrano Á, de Diego-García L, Henshall DC, Engel T, Díaz-Hernández M. Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels. Frontiers in Pharmacology. 9: 170. PMID 29551976 DOI: 10.3389/fphar.2018.00170 |
0.324 |
|
| 2018 |
Brennan GP, Henshall DC. microRNAs in the pathophysiology of epilepsy. Neuroscience Letters. 667: 47-52. PMID 28104433 DOI: 10.1016/j.neulet.2017.01.017 |
0.456 |
|
| 2018 |
Glasgow A, Vencken S, Santi CD, Raoof R, Henshall D, Linnane B, Mcnally P, Greene C. The TLR4 regulator miR-21 is downregulated in the paediatric cystic fibrosis airway European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa3420 |
0.418 |
|
| 2017 |
Bielefeld P, Mooney C, Henshall DC, Fitzsimons CP. miRNA-Mediated Regulation of Adult Hippocampal Neurogenesis; Implications for Epilepsy. Brain Plasticity (Amsterdam, Netherlands). 3: 43-59. PMID 29765859 DOI: 10.3233/BPL-160036 |
0.405 |
|
| 2017 |
Rodriguez AS, Engel T, Palfi A, Farrar GJ, Henshall DC, Jimenez-Mateos EM. Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy. International Journal of Physiology, Pathophysiology and Pharmacology. 9: 178-187. PMID 29348794 |
0.476 |
|
| 2017 |
Alves M, Gomez-Villafuertes R, Delanty N, Farrell MA, O'Brien DF, Miras-Portugal MT, Hernandez MD, Henshall DC, Engel T. Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy. Epilepsia. PMID 28733972 DOI: 10.1111/epi.13850 |
0.339 |
|
| 2017 |
Aronica E, Bauer S, Bozzi Y, Caleo M, Dingledine R, Gorter JA, Henshall DC, Kaufer D, Koh S, Löscher W, Louboutin JP, Mishto M, Norwood BA, Palma E, Poulter MO, et al. Neuroinflammatory targets and treatments for epilepsy validated in experimental models. Epilepsia. 58: 27-38. PMID 28675563 DOI: 10.1111/Epi.13783 |
0.331 |
|
| 2017 |
Engel T, Lucas JJ, Henshall DC. Targeting the proteasome in epilepsy. Oncotarget. PMID 28611313 DOI: 10.18632/oncotarget.18418 |
0.352 |
|
| 2017 |
Raoof R, Jimenez-Mateos EM, Bauer S, Tackenberg B, Rosenow F, Lang J, Onugoren MD, Hamer H, Huchtemann T, Körtvélyessy P, Connolly NMC, Pfeiffer S, Prehn JHM, Farrell MA, O'Brien DF, ... Henshall DC, et al. Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus. Scientific Reports. 7: 3328. PMID 28607431 DOI: 10.1038/S41598-017-02969-6 |
0.549 |
|
| 2017 |
McArdle H, Jimenez-Mateos EM, Raoof R, Carthy E, Boyle D, ElNaggar H, Delanty N, Hamer H, Dogan M, Huchtemann T, Kӧrtvelyessy P, Rosenow F, Forster RJ, Henshall DC, Spain E. "TORNADO" - Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid. Scientific Reports. 7: 1750. PMID 28496112 DOI: 10.1038/S41598-017-01947-2 |
0.438 |
|
| 2017 |
Rajman M, Metge F, Fiore R, Khudayberdiev S, Aksoy-Aksel A, Bicker S, Ruedell Reschke C, Raoof R, Brennan GP, Delanty N, Farrell MA, O'Brien DF, Bauer S, Norwood B, Veno MT, ... ... Henshall DC, et al. A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. The Embo Journal. PMID 28487411 DOI: 10.15252/Embj.201695748 |
0.466 |
|
| 2017 |
Hauser RM, Henshall DC, Lubin FD. The Epigenetics of Epilepsy and Its Progression. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858417705840. PMID 28468530 DOI: 10.1177/1073858417705840 |
0.411 |
|
| 2017 |
Reynolds JP, Jimenez-Mateos EM, Cao L, Bian F, Alves M, Miller-Delaney SF, Zhou A, Henshall DC. Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury. Neurochemical Research. PMID 28397067 DOI: 10.1007/s11064-017-2260-6 |
0.359 |
|
| 2017 |
Henshall DC. Manipulating MicroRNAs in Murine Models: Targeting the Multi-Targeting in Epilepsy. Epilepsy Currents. 17: 43-47. PMID 28331471 DOI: 10.5698/1535-7511-17.1.43 |
0.473 |
|
| 2017 |
Reschke CR, Silva LF, Norwood BA, Senthilkumar K, Morris G, Sanz-Rodriguez A, Conroy RM, Costard L, Neubert V, Bauer S, Farrell MA, O'Brien DF, Delanty N, Schorge S, Pasterkamp RJ, ... ... Henshall DC, et al. Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy. Molecular Therapy. Nucleic Acids. 6: 45-56. PMID 28325299 DOI: 10.1016/J.Omtn.2016.11.002 |
0.492 |
|
| 2017 |
Engel T, Martinez-Villarreal J, Henke C, Jimenez-Mateos EM, Sanz-Rodriguez A, Alves M, Hernandez-Santana Y, Brennan GP, Kenny A, Campbell A, Lucas JJ, Henshall DC. Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury. Molecular Neurodegeneration. 12: 21. PMID 28235423 DOI: 10.1186/s13024-017-0163-2 |
0.309 |
|
| 2017 |
Mooney CM, Jimenez-Mateos EM, Engel T, Mooney C, Diviney M, Venø MT, Kjems J, Farrell MA, O'Brien DF, Delanty N, Henshall DC. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Scientific Reports. 7: 41517. PMID 28128343 DOI: 10.1038/Srep41517 |
0.394 |
|
| 2017 |
Rodriguez-Alvarez N, Jimenez-Mateos EM, Engel T, Quinlan S, Reschke CR, Conroy RM, Bhattacharya A, Boylan GB, Henshall DC. Effects of P2X7 receptor antagonists on hypoxia-induced neonatal seizures in mice. Neuropharmacology. PMID 28082183 DOI: 10.1016/j.neuropharm.2017.01.005 |
0.435 |
|
| 2017 |
Ichikawa N, Alves M, Pfeiffer S, Langa E, Hernández-Santana YE, Suzuki H, Prehn JH, Engel T, Henshall DC. Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice. Cell Death & Disease. 8: e2556. PMID 28079889 DOI: 10.1038/cddis.2016.301 |
0.429 |
|
| 2017 |
Engel T, Brennan GP, Sanz-Rodriguez A, Alves M, Beamer E, Watters O, Henshall DC, Jimenez-Mateos EM. A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22. Biochimica Et Biophysica Acta. Molecular Cell Research. 1864: 255-266. PMID 27840225 DOI: 10.1016/j.bbamcr.2016.11.007 |
0.365 |
|
| 2017 |
Quinlan S, Henke C, Brennan GP, Henshall DC, Jimenez-Mateos EM. Detection of MicroRNAs in Brain Slices Using In Situ Hybridization. Methods in Molecular Biology (Clifton, N.J.). 1509: 85-91. PMID 27826920 DOI: 10.1007/978-1-4939-6524-3_9 |
0.3 |
|
| 2016 |
Henshall DC, Hamer HM, Pasterkamp RJ, Goldstein DB, Kjems J, Prehn JHM, Schorge S, Lamottke K, Rosenow F. MicroRNAs in epilepsy: pathophysiology and clinical utility. The Lancet. Neurology. 15: 1368-1376. PMID 27839653 DOI: 10.1016/S1474-4422(16)30246-0 |
0.513 |
|
| 2016 |
Almeida Silva LF, Engel T, Reschke CR, Conroy RM, Langa E, Henshall DC. Distinct behavioral and epileptic phenotype differences in 129/P mice compared to C57BL/6 mice subject to intraamygdala kainic acid-induced status epilepticus. Epilepsy & Behavior : E&B. 64: 186-194. PMID 27744244 DOI: 10.1016/j.yebeh.2016.09.031 |
0.35 |
|
| 2016 |
Gross C, Yao X, Engel T, Tiwari D, Xing L, Rowley S, Danielson SW, Thomas KT, Jimenez-Mateos EM, Schroeder LM, Pun RY, Danzer SC, Henshall DC, Bassell GJ. MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset. Cell Reports. 17: 37-45. PMID 27681419 DOI: 10.1016/J.Celrep.2016.08.074 |
0.582 |
|
| 2016 |
Sebastián-Serrano Á, Engel T, de Diego-García L, Olivos-Oré LA, Arribas-Blázquez M, Martínez-Frailes C, Pérez-Díaz C, Millán JL, Artalejo AR, Miras-Portugal MT, Henshall DC, Díaz-Hernández M. Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. Human Molecular Genetics. PMID 27466191 DOI: 10.1093/hmg/ddw248 |
0.392 |
|
| 2016 |
Fischer W, Franke H, Krügel U, Müller H, Dinkel K, Lord B, Letavic MA, Henshall DC, Engel T. Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models. Plos One. 11: e0156468. PMID 27281030 DOI: 10.1371/journal.pone.0156468 |
0.361 |
|
| 2016 |
Jimenez-Pacheco A, Diaz-Hernandez M, Arribas-Blázquez M, Sanz-Rodriguez A, Olivos-Oré LA, Artalejo AR, Alves M, Letavic M, Miras-Portugal MT, Conroy RM, Delanty N, Farrell MA, O'Brien DF, Bhattacharya A, Engel T, ... Henshall DC, et al. Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5920-32. PMID 27251615 DOI: 10.1523/JNEUROSCI.4009-15.2016 |
0.345 |
|
| 2016 |
Cattani AA, Allene C, Seifert V, Rosenow F, Henshall DC, Freiman TM. Involvement of microRNAs in epileptogenesis. Epilepsia. PMID 27207608 DOI: 10.1111/Epi.13404 |
0.529 |
|
| 2016 |
Mooney C, Becker BA, Raoof R, Henshall DC. EpimiRBase: a comprehensive database of microRNA-epilepsy associations. Bioinformatics (Oxford, England). PMID 26748106 DOI: 10.1093/bioinformatics/btw008 |
0.506 |
|
| 2016 |
Engel T, Alves M, Sheedy C, Henshall DC. ATPergic signalling during seizures and epilepsy. Neuropharmacology. 104: 140-53. PMID 26549853 DOI: 10.1016/j.neuropharm.2015.11.001 |
0.414 |
|
| 2016 |
McKiernan P, Mooney C, Henshall D, Linnane B, McNally P, Greene C. Serum microRNA levels in paediatric females versus males with cystic fibrosis European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa898 |
0.457 |
|
| 2016 |
Engel T, Alves M, Sheedy C, Henshall DC. ATPergic signalling during seizures and epilepsy Neuropharmacology. 104: 140-153. DOI: 10.1016/j.neuropharm.2015.11.001 |
0.413 |
|
| 2015 |
Mooney C, Raoof R, El-Naggar H, Sanz-Rodriguez A, Jimenez-Mateos EM, Henshall DC. High Throughput qPCR Expression Profiling of Circulating MicroRNAs Reveals Minimal Sex- and Sample Timing-Related Variation in Plasma of Healthy Volunteers. Plos One. 10: e0145316. PMID 26699132 DOI: 10.1371/journal.pone.0145316 |
0.423 |
|
| 2015 |
Reschke CR, Henshall DC. microRNA and Epilepsy. Advances in Experimental Medicine and Biology. 888: 41-70. PMID 26663178 DOI: 10.1007/978-3-319-22671-2_4 |
0.555 |
|
| 2015 |
Jimenez-Mateos EM, Arribas-Blazquez M, Sanz-Rodriguez A, Concannon C, Olivos-Ore LA, Reschke CR, Mooney CM, Mooney C, Lugara E, Morgan J, Langa E, Jimenez-Pacheco A, Silva LF, Mesuret G, Boison D, ... ... Henshall DC, et al. microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. Scientific Reports. 5: 17486. PMID 26631939 DOI: 10.1038/srep17486 |
0.494 |
|
| 2015 |
Henshall DC, Kobow K. Epigenetics and Epilepsy. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26438606 DOI: 10.1101/cshperspect.a022731 |
0.328 |
|
| 2015 |
Rodriguez-Alvarez N, Jimenez-Mateos EM, Dunleavy M, Waddington JL, Boylan GB, Henshall DC. Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice. Neurobiology of Disease. 83: 100-14. PMID 26341542 DOI: 10.1016/j.nbd.2015.08.023 |
0.412 |
|
| 2015 |
Brennan GP, Jimenez-Mateos EM, Sanz-Rodriguez A, Mooney CM, Tzivion G, Henshall DC, Engel T. Overexpression of 14-3-3ζ Increases Brain Levels of C/EBP Homologous Protein CHOP. Journal of Molecular Neuroscience : Mn. 56: 255-62. PMID 25854777 DOI: 10.1007/S12031-015-0510-0 |
0.426 |
|
| 2015 |
Henshall DC, Engel T. P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus. Epilepsy & Behavior : E&B. 49: 8-12. PMID 25843343 DOI: 10.1016/j.yebeh.2015.02.031 |
0.366 |
|
| 2015 |
Miller-Delaney SF, Bryan K, Das S, McKiernan RC, Bray IM, Reynolds JP, Gwinn R, Stallings RL, Henshall DC. Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy. Brain : a Journal of Neurology. 138: 616-31. PMID 25552301 DOI: 10.1093/brain/awu373 |
0.417 |
|
| 2015 |
Jimenez-Mateos EM, Engel T, Merino-Serrais P, Fernaud-Espinosa I, Rodriguez-Alvarez N, Reynolds J, Reschke CR, Conroy RM, McKiernan RC, deFelipe J, Henshall DC. Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus. Brain Structure & Function. 220: 2387-99. PMID 24874920 DOI: 10.1007/s00429-014-0798-5 |
0.54 |
|
| 2015 |
Spain E, Jimenez-Mateos EM, Raoof R, ElNaggar H, Delanty N, Forster RJ, Henshall DC. Direct, non-amplified detection of microRNA-134 in plasma from epilepsy patients Rsc Advances. 5: 90071-90078. DOI: 10.1039/C5Ra16352H |
0.49 |
|
| 2014 |
Dunleavy M, Schindler CK, Shinoda S, Crilly S, Henshall DC. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International Journal of Physiology, Pathophysiology and Pharmacology. 6: 199-208. PMID 25755841 |
0.324 |
|
| 2014 |
Mesuret G, Engel T, Hessel EV, Sanz-Rodriguez A, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC. P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage Cns Neuroscience and Therapeutics. 20: 556-564. PMID 24750893 DOI: 10.1111/cns.12272 |
0.413 |
|
| 2014 |
Nolan K, Mitchem MR, Jimenez-Mateos EM, Henshall DC, Concannon CG, Prehn JH. Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition. Journal of Molecular Neuroscience : Mn. 53: 231-41. PMID 24696165 DOI: 10.1007/s12031-014-0290-y |
0.343 |
|
| 2014 |
Henshall DC. MicroRNA and epilepsy: profiling, functions and potential clinical applications. Current Opinion in Neurology. 27: 199-205. PMID 24553459 DOI: 10.1097/WCO.0000000000000079 |
0.439 |
|
| 2013 |
Henshall DC, Diaz-Hernandez M, Miras-Portugal MT, Engel T. P2X receptors as targets for the treatment of status epilepticus. Frontiers in Cellular Neuroscience. 7: 237. PMID 24324404 DOI: 10.3389/fncel.2013.00237 |
0.335 |
|
| 2013 |
Henshall DC. MicroRNAs in the pathophysiology and treatment of status epilepticus. Frontiers in Molecular Neuroscience. 6: 37. PMID 24282394 DOI: 10.3389/fnmol.2013.00037 |
0.6 |
|
| 2013 |
Henshall DC. Antagomirs and microRNA in status epilepticus. Epilepsia. 54: 17-9. PMID 24001063 DOI: 10.1111/epi.12267 |
0.458 |
|
| 2013 |
Henshall DC, Engel T. Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts. Frontiers in Cellular Neuroscience. 7: 110. PMID 23882182 DOI: 10.3389/fncel.2013.00110 |
0.361 |
|
| 2013 |
Jimenez-Pacheco A, Mesuret G, Sanz-Rodriguez A, Tanaka K, Mooney C, Conroy R, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC, Engel T. Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079 Epilepsia. 54: 1551-1561. PMID 23808395 DOI: 10.1111/epi.12257 |
0.437 |
|
| 2013 |
Moran C, Sanz-Rodriguez A, Jimenez-Pacheco A, Martinez-Villareal J, McKiernan RC, Jimenez-Mateos EM, Mooney C, Woods I, Prehn JHM, Henshall DC, Engel T. Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death Cell Death and Disease. 4. PMID 23618904 DOI: 10.1038/cddis.2013.136 |
0.394 |
|
| 2013 |
Jimenez-Mateos EM, Henshall DC. Epilepsy and microRNA. Neuroscience. 238: 218-29. PMID 23485811 DOI: 10.1016/j.neuroscience.2013.02.027 |
0.583 |
|
| 2013 |
Engel T, Sanz-Rodgriguez A, Jimenez-Mateos EM, Concannon CG, Jimenez-Pacheco A, Moran C, Mesuret G, Petit E, Delanty N, Farrell MA, O'Brien DF, Prehn JH, Lucas JJ, Henshall DC. CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain : a Journal of Neurology. 136: 577-92. PMID 23361066 DOI: 10.1093/brain/aws337 |
0.435 |
|
| 2013 |
Brennan GP, Jimenez-Mateos EM, McKiernan RC, Engel T, Tzivion G, Henshall DC. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. Plos One. 8: e54491. PMID 23359526 DOI: 10.1371/Journal.Pone.0054491 |
0.31 |
|
| 2013 |
Michalak Z, Sano T, Engel T, Miller-Delaney SFC, Lerner-Natoli M, Henshall DC. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice Epilepsy Research. 103: 167-179. PMID 23182415 DOI: 10.1016/j.eplepsyres.2012.10.006 |
0.358 |
|
| 2013 |
Henshall DC, Diaz-Hernandez M, Miras-Portugal MT, Engel T. P2X receptors as targets for the treatment of status epilepticus Frontiers in Cellular Neuroscience. 7. DOI: 10.3389/fncel.2013.00237 |
0.336 |
|
| 2013 |
Henshall DC, Engel T. Contribution of apoptosis-associated signaling pathways to epileptogenesis: Lessons from Bcl-2 family knockouts Frontiers in Cellular Neuroscience. DOI: 10.3389/fncel.2013.00110 |
0.361 |
|
| 2012 |
Engel T, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC. P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. International Journal of Physiology, Pathophysiology and Pharmacology. 4: 174-87. PMID 23320131 |
0.321 |
|
| 2012 |
Heverin M, Engel T, Meaney S, Jimenez-Mateos EM, Al-Saudi R, Henshall DC. Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice. Brain Research. 1480: 81-90. PMID 22921849 DOI: 10.1016/j.brainres.2012.08.018 |
0.372 |
|
| 2012 |
Michalak Z, Lebrun A, Di Miceli M, Rousset MC, Crespel A, Coubes P, Henshall DC, Lerner-Natoli M, Rigau V. IgG leakage may contribute to neuronal dysfunction in drug-refractory epilepsies with blood-brain barrier disruption. Journal of Neuropathology and Experimental Neurology. 71: 826-38. PMID 22878666 DOI: 10.1097/NEN.0b013e31826809a6 |
0.318 |
|
| 2012 |
McKiernan RC, Jimenez-Mateos EM, Sano T, Bray I, Stallings RL, Simon RP, Henshall DC. Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Experimental Neurology. 237: 346-54. PMID 22771761 DOI: 10.1016/j.expneurol.2012.06.029 |
0.608 |
|
| 2012 |
Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, ... ... Henshall DC, et al. Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nature Medicine. 18: 1087-94. PMID 22683779 DOI: 10.1038/nm.2834 |
0.622 |
|
| 2012 |
McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, Michalak Z, Moran C, Delanty N, Farrell M, O'Brien D, Meller R, Simon RP, Stallings RL, Henshall DC. Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. Plos One. 7: e35921. PMID 22615744 DOI: 10.1371/journal.pone.0035921 |
0.481 |
|
| 2012 |
Sano T, Reynolds JP, Jimenez-Mateos EM, Matsushima S, Taki W, Henshall DC. MicroRNA-34a upregulation during seizure-induced neuronal death. Cell Death & Disease. 3: e287. PMID 22436728 DOI: 10.1038/cddis.2012.23 |
0.556 |
|
| 2012 |
Kilany A, Raouf ERA, Gaber AA, Aloush TK, Aref HA, Anwar M, Henshall DC, Abdulghani MO. Elevated serum Bcl-2 in children with temporal lobe epilepsy Seizure. 21: 250-253. PMID 22365585 DOI: 10.1016/j.seizure.2012.01.004 |
0.342 |
|
| 2012 |
Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M. Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1616-28. PMID 22198387 DOI: 10.1096/fj.11-196089 |
0.398 |
|
| 2011 |
Jimenez-Mateos EM, Bray I, Sanz-Rodriguez A, Engel T, McKiernan RC, Mouri G, Tanaka K, Sano T, Saugstad JA, Simon RP, Stallings RL, Henshall DC. miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. The American Journal of Pathology. 179: 2519-32. PMID 21945804 DOI: 10.1016/j.ajpath.2011.07.036 |
0.608 |
|
| 2011 |
Bozzi Y, Dunleavy M, Henshall DC. Cell signaling underlying epileptic behavior. Frontiers in Behavioral Neuroscience. 5: 45. PMID 21852968 DOI: 10.3389/fnbeh.2011.00045 |
0.392 |
|
| 2011 |
Thompson SJ, Ashley MD, Stöhr S, Schindler C, Li M, McCarthy-Culpepper KA, Pearson AN, Xiong ZG, Simon RP, Henshall DC, Meller R. Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 120-32. PMID 21760970 |
0.387 |
|
| 2011 |
Engel T, Schindler CK, Sanz-Rodriguez A, Conroy RM, Meller R, Simon RP, Henshall DC. Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 38-47. PMID 21479101 |
0.336 |
|
| 2010 |
Engel T, Tanaka K, Jimenez-Mateos EM, Caballero-Caballero A, Prehn JH, Henshall DC. Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus. Cell Death & Disease. 1: e79. PMID 21368852 DOI: 10.1038/cddis.2010.55 |
0.409 |
|
| 2010 |
Jimenez-Mateos EM, Mouri G, Conroy RM, Henshall DC. Epileptic tolerance is associated with enduring neuroprotection and uncoupling of the relationship between CA3 damage, neuropeptide Y rearrangement and spontaneous seizures following intra-amygdala kainic acid-induced status epilepticus in mice. Neuroscience. 171: 556-65. PMID 20837105 DOI: 10.1016/j.neuroscience.2010.09.003 |
0.404 |
|
| 2010 |
Engel T, Caballero-Caballero A, Schindler CK, Plesnila N, Strasser A, Prehn JH, Henshall DC. BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor. Journal of Neurochemistry. 115: 92-101. PMID 20646170 DOI: 10.1111/j.1471-4159.2010.06909.x |
0.322 |
|
| 2010 |
Engel T, Hatazaki S, Tanaka K, Prehn JH, Henshall DC. Deletion of Puma protects hippocampal neurons in a model of severe status epilepticus. Neuroscience. 168: 443-50. PMID 20362645 DOI: 10.1016/j.neuroscience.2010.03.057 |
0.359 |
|
| 2010 |
Dunleavy M, Shinoda S, Schindler C, Ewart C, Dolan R, Gobbo OL, Kerskens CM, Henshall DC. Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis. The American Journal of Pathology. 176: 330-42. PMID 19948825 DOI: 10.2353/ajpath.2010.090119 |
0.369 |
|
| 2010 |
Tanaka K, Jimenez-Mateos EM, Matsushima S, Taki W, Henshall DC. Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice. Epilepsy Research. 88: 151-61. PMID 19931419 DOI: 10.1016/j.eplepsyres.2009.10.012 |
0.405 |
|
| 2010 |
Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 853-61. PMID 19890018 DOI: 10.1096/fj.09-145870 |
0.402 |
|
| 2010 |
Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, ... Henshall DC, et al. Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus. Cell Death and Differentiation. 17: 459-68. PMID 19779495 DOI: 10.1038/Cdd.2009.134 |
0.385 |
|
| 2010 |
Henshall DC, Meldrum BS. Cell death after single and repeated brief seizures Epilepsia. 51: 35. DOI: 10.1111/j.1528-1167.2010.02821.x |
0.385 |
|
| 2009 |
Jimenez-Mateos EM, Henshall DC. Seizure preconditioning and epileptic tolerance: models and mechanisms. International Journal of Physiology, Pathophysiology and Pharmacology. 1: 180-191. PMID 21383886 |
0.416 |
|
| 2009 |
Engel T, Henshall DC. Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? International Journal of Physiology, Pathophysiology and Pharmacology. 1: 97-115. PMID 21383882 |
0.4 |
|
| 2009 |
Henshall DC, Dürmüller N, White HS, Williams R, Moser P, Dunleavy M, Silverstone PH. Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents. Neuropsychiatric Disease and Treatment. 5: 189-206. PMID 19557114 DOI: 10.2147/Ndt.S4714 |
0.37 |
|
| 2008 |
Jimenez-Mateos EM, Hatazaki S, Johnson MB, Bellver-Estelles C, Mouri G, Bonner C, Prehn JH, Meller R, Simon RP, Henshall DC. Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiology of Disease. 32: 442-53. PMID 18804535 DOI: 10.1016/j.nbd.2008.08.008 |
0.39 |
|
| 2008 |
Murphy N, Yamamoto A, Henshall DC. Detection of 14-3-3zeta in cerebrospinal fluid following experimentally evoked seizures. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 13: 377-84. PMID 18484353 DOI: 10.1080/13547500802027971 |
0.405 |
|
| 2008 |
Mouri G, Jimenez-Mateos E, Engel T, Dunleavy M, Hatazaki S, Paucard A, Matsushima S, Taki W, Henshall DC. Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Research. 1213: 140-51. PMID 18455706 DOI: 10.1016/j.brainres.2008.03.061 |
0.391 |
|
| 2008 |
O'Sullivan GJ, Dunleavy M, Hakansson K, Clementi M, Kinsella A, Croke DT, Drago J, Fienberg AA, Greengard P, Sibley DR, Fisone G, Henshall DC, Waddington JL. Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling. Neuropharmacology. 54: 1051-61. PMID 18367215 DOI: 10.1016/J.Neuropharm.2008.02.011 |
0.31 |
|
| 2007 |
Engel T, Murphy BM, Schindler CK, Henshall DC. Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy Research. 77: 151-6. PMID 17942278 DOI: 10.1016/j.eplepsyres.2007.09.001 |
0.346 |
|
| 2007 |
Hatazaki S, Bellver-Estelles C, Jimenez-Mateos EM, Meller R, Bonner C, Murphy N, Matsushima S, Taki W, Prehn JH, Simon RP, Henshall DC. Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning. Neuroscience. 150: 467-77. PMID 17935890 DOI: 10.1016/j.neuroscience.2007.09.020 |
0.423 |
|
| 2007 |
Henshall DC, Murphy BM. Modulators of neuronal cell death in epilepsy. Current Opinion in Pharmacology. 8: 75-81. PMID 17827063 DOI: 10.1016/J.COPH.2007.07.005 |
0.401 |
|
| 2007 |
Murphy B, Dunleavy M, Shinoda S, Schindler C, Meller R, Bellver-Estelles C, Hatazaki S, Dicker P, Yamamoto A, Koegel I, Chu X, Wang W, Xiong Z, Prehn J, Simon R, ... Henshall D, et al. Bcl-w protects hippocampus during experimental status epilepticus. The American Journal of Pathology. 171: 1258-68. PMID 17702891 DOI: 10.2353/Ajpath.2007.070269 |
0.495 |
|
| 2007 |
Henshall DC. Apoptosis signalling pathways in seizure-induced neuronal death and epilepsy. Biochemical Society Transactions. 35: 421-3. PMID 17371290 DOI: 10.1042/BST0350421 |
0.369 |
|
| 2006 |
Schindler CK, Heverin M, Henshall DC. Isoform- and subcellular fraction-specific differences in hippocampal 14-3-3 levels following experimentally evoked seizures and in human temporal lobe epilepsy. Journal of Neurochemistry. 99: 561-9. PMID 16981892 DOI: 10.1111/j.1471-4159.2006.04153.x |
0.398 |
|
| 2006 |
Yamamoto A, Schindler CK, Murphy BM, Bellver-Estelles C, So NK, Taki W, Meller R, Simon RP, Henshall DC. Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy. Experimental Neurology. 202: 410-20. PMID 16919273 DOI: 10.1016/j.expneurol.2006.07.003 |
0.321 |
|
| 2006 |
Meller R, Clayton C, Torrey DJ, Schindler CK, Lan JQ, Cameron JA, Chu XP, Xiong ZG, Simon RP, Henshall DC. Activation of the caspase 8 pathway mediates seizure-induced cell death in cultured hippocampal neurons. Epilepsy Research. 70: 3-14. PMID 16542823 DOI: 10.1016/j.eplepsyres.2006.02.002 |
0.34 |
|
| 2006 |
Henshall DC, Simon RP. Epilepsy and apoptosis pathways. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1557-72. PMID 15889042 DOI: 10.1038/sj.jcbfm.9600149 |
0.409 |
|
| 2004 |
Araki T, Shinoda S, Schindler CK, Quan-Lan J, Meller R, Taki W, Simon RP, Henshall DC. Expression, interaction, and proteolysis of death-associated protein kinase and p53 within vulnerable and resistant hippocampal subfields following seizures. Hippocampus. 14: 326-36. PMID 15132432 DOI: 10.1002/HIPO.10184 |
0.355 |
|
| 2004 |
Shinoda S, Schindler CK, Meller R, So NK, Araki T, Yamamoto A, Lan JQ, Taki W, Simon RP, Henshall DC. Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. The Journal of Clinical Investigation. 113: 1059-68. PMID 15057313 DOI: 10.1172/JCI19971 |
0.448 |
|
| 2004 |
Shinoda S, Araki T, Lan JQ, Schindler CK, Simon RP, Taki W, Henshall DC. Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse. Journal of Neuroscience Research. 76: 121-8. PMID 15048936 DOI: 10.1002/jnr.20064 |
0.389 |
|
| 2004 |
Henshall DC, Schindler CK, So NK, Lan JQ, Meller R, Simon RP. Death-associated protein kinase expression in human temporal lobe epilepsy. Annals of Neurology. 55: 485-94. PMID 15048887 DOI: 10.1002/ana.20001 |
0.304 |
|
| 2004 |
Schindler CK, Shinoda S, Simon RP, Henshall DC. Subcellular distribution of Bcl-2 family proteins and 14-3-3 within the hippocampus during seizure-induced neuronal death in the rat. Neuroscience Letters. 356: 163-6. PMID 15036620 DOI: 10.1016/j.neulet.2003.11.048 |
0.377 |
|
| 2003 |
Henshall DC, Araki T, Schindler CK, Shinoda S, Lan JQ, Simon RP. Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures. Journal of Neurochemistry. 86: 1260-70. PMID 12911633 DOI: 10.1046/j.1471-4159.2003.01934.x |
0.35 |
|
| 2003 |
Shinoda S, Schindler CK, Quan-Lan J, Saugstad JA, Taki W, Simon RP, Henshall DC. Interaction of 14-3-3 with Bid during seizure-induced neuronal death. Journal of Neurochemistry. 86: 460-9. PMID 12871587 DOI: 10.1046/j.1471-4159.2003.01860.x |
0.347 |
|
| 2003 |
Meller R, Schindler CK, Chu XP, Xiong ZG, Cameron JA, Simon RP, Henshall DC. Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. Cell Death and Differentiation. 10: 539-47. PMID 12728252 DOI: 10.1038/sj.cdd.4401206 |
0.386 |
|
| 2002 |
Henshall DC, Araki T, Schindler CK, Lan JQ, Tiekoter KL, Taki W, Simon RP. Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8458-65. PMID 12351720 |
0.318 |
|
| 2002 |
Araki T, Simon RP, Taki W, Lan JQ, Henshall DC. Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. Journal of Neuroscience Research. 69: 614-21. PMID 12210827 DOI: 10.1002/jnr.10356 |
0.384 |
|
| 2002 |
Henshall DC, Skradski SL, Meller R, Araki T, Minami M, Schindler CK, Lan JQ, Bonislawski DP, Simon RP. Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. Neurobiology of Disease. 10: 71-87. PMID 12127146 DOI: 10.1006/Nbdi.2002.0505 |
0.378 |
|
| 2002 |
Henshall D, Sinclair J, Simon R. Relationship between seizure-induced transcription of the DNA damage-inducible gene GADD45, DNA fragmentation, and neuronal death in focally evoked limbic epilepsy. Journal of Neurochemistry. 73: 1573-1583. PMID 10501203 DOI: 10.1046/J.1471-4159.1999.0731573.X |
0.449 |
|
| 2001 |
Henshall DC, Bonislawski DP, Skradski SL, Araki T, Lan JQ, Schindler CK, Meller R, Simon RP. Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death Cell Death and Differentiation. 8: 1169-1181. PMID 11753565 DOI: 10.1038/sj.cdd.4400921 |
0.377 |
|
| 2001 |
Henshall DC, Bonislawski DP, Skradski SL, Lan JQ, Meller R, Simon RP. Cleavage of Bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures Neurobiology of Disease. 8: 568-580. PMID 11493022 DOI: 10.1006/Nbdi.2001.0415 |
0.357 |
|
| 2001 |
Henshall DC, Skradski SL, Lan JQ, Ren T, Simon RP. Increased Bcl-w expression following focally evoked limbic seizures in the rat Neuroscience Letters. 305: 153-156. PMID 11403928 DOI: 10.1016/S0304-3940(01)01849-3 |
0.401 |
|
| 2001 |
Henshall DC, Skradski SL, Bonislawski DP, Lan JQ, Simon RP. Caspase-2 activation is redundant during seizure-induced neuronal death Journal of Neurochemistry. 77: 886-895. PMID 11331417 DOI: 10.1046/J.1471-4159.2001.00291.X |
0.34 |
|
| 2000 |
Henshall DC, Clark RS, Adelson PD, Chen M, Watkins SC, Simon RP. Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy. Neurology. 55: 250-7. PMID 10908900 DOI: 10.1212/WNL.55.2.250 |
0.345 |
|
| 2000 |
Henshall DC, Sinclair J, Simon RP. Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures. Brain Research. 858: 290-302. PMID 10708680 DOI: 10.1016/S0006-8993(99)02452-X |
0.386 |
|
| 2000 |
Henshall DC, Chen J, Simon RP. Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. Journal of Neurochemistry. 74: 1215-23. PMID 10693954 DOI: 10.1046/J.1471-4159.2000.741215.X |
0.395 |
|
| 1998 |
Tanaka K, Henshall DC, Waga S, Shimosaka S, Simon RP. Bilateral intranigral NMDA infusion suppresses neuronal injury without affecting the duration of kainic acid-induced seizures in rats. Neuroscience Letters. 251: 69-71. PMID 9714467 DOI: 10.1016/S0304-3940(98)00483-2 |
0.354 |
|
| Show low-probability matches. |