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Moureq Rashed Alotaibi - Publications

Affiliations: 
King Saud University 
Area:
Cancer pharmacology
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Softah A, Alotaibi MR, Alhoshani AR, Saleh T, Alhazzani K, Almutairi MM, AlRowis R, Alshehri S, Albekairy NA, Harada H, Boyd R, Chakraborty E, Gewirtz DA, As Sobeai HM. The Combination of Radiation with PARP Inhibition Enhances Senescence and Sensitivity to the Senolytic, Navitoclax, in Triple Negative Breast Tumor Cells. Biomedicines. 11. PMID 38002066 DOI: 10.3390/biomedicines11113066  0.652
2023 El-Sadoni M, Shboul SA, Alhesa A, Shahin NA, Alsharaiah E, Ismail MA, Ababneh NA, Alotaibi MR, Azab B, Saleh T. A three-marker signature identifies senescence in human breast cancer exposed to neoadjuvant chemotherapy. Cancer Chemotherapy and Pharmacology. PMID 36964435 DOI: 10.1007/s00280-023-04523-w  0.353
2022 Saleh T, As Sobeai HM, Alhoshani A, Alhazzani K, Almutairi MM, Alotaibi M. Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells. Medicina (Kaunas, Lithuania). 58. PMID 35888608 DOI: 10.3390/medicina58070889  0.43
2022 Sulaiman AAA, Sobeai HMA, Aldawood E, Abogosh A, Alhazzani K, Alotaibi MR, Ahmad S, Alhoshani A, Isab AA. In vitro and in vivo antitumor studies of potential anticancer agents of platinum(II) complexes of dicyclopentadiene and dithiocarbamates§. Metallomics : Integrated Biometal Science. 14. PMID 35869976 DOI: 10.1093/mtomcs/mfac054  0.365
2021 Alanazi FE, As Sobeai HM, Alhazzani K, Al-Dhfyan A, Alshammari MA, Alotaibi M, Al-Hosaini K, Korashy HM, Alhoshani A. Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies. Saudi Pharmaceutical Journal : Spj : the Official Publication of the Saudi Pharmaceutical Society. 30: 138-149. PMID 35528855 DOI: 10.1016/j.jsps.2021.12.014  0.367
2021 Alhoshani A, Alotaibi M, As Sobeai HM, Alharbi N, Alhazzani K, Al-Dhfyan A, Alanazi FE, Korashy HM. In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis. Saudi Journal of Biological Sciences. 28: 7396-7403. PMID 34867043 DOI: 10.1016/j.sjbs.2021.08.051  0.342
2021 Alhoshani A, Sulaiman AAA, Sobeai HMA, Qamar W, Alotaibi M, Alhazzani K, Monim-Ul-Mehboob M, Ahmad S, Isab AA. Anticancer Activity and Apoptosis Induction of Gold(III) Complexes Containing 2,2'-Bipyridine-3,3'-dicarboxylic Acid and Dithiocarbamates. Molecules (Basel, Switzerland). 26. PMID 34209921 DOI: 10.3390/molecules26133973  0.314
2020 Nadeem A, Ahmad SF, Al-Harbi NO, Ibrahim KE, Alqahtani F, AsSobeai HM, Alotaibi M. Inhibition of interleukin-2-inducible T-cell kinase causes reduction in imiquimod-induced psoriasiform inflammation through reduction of Th17 cells and enhancement of Treg cells in mice. Biochimie. PMID 33007409 DOI: 10.1016/j.biochi.2020.09.023  0.318
2020 Saleh T, Carpenter VJ, Tyutyunyk-Massey L, Murray G, Leverson JD, Souers AJ, Alotaibi MR, Faber A, Reed J, Harada H, Gewirtz DA. Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X -BAX Interaction. Molecular Oncology. PMID 32652830 DOI: 10.1002/1878-0261.12761  0.668
2020 Attia SM, Al-Khalifa MK, Al-Hamamah MA, Alotaibi MR, Attia MSM, Ahmad SF, Ansari MA, Nadeem A, Bakheet SA. Vorinostat is genotoxic and epigenotoxic in the mouse bone marrow cells at the human equivalent doses. Toxicology. 152507. PMID 32512035 DOI: 10.1016/J.Tox.2020.152507  0.402
2020 Alhoshani A, Alanazi FE, Alotaibi MR, Attwa MW, Kadi AA, Aldhfyan A, Akhtar S, Hourani S, Agouni A, Zeidan A, Korashy HM. EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: and Rat Studies. Chemical Research in Toxicology. PMID 32370496 DOI: 10.1021/Acs.Chemrestox.0C00005  0.397
2020 Al-Harbi NO, Nadeem A, Ahmad SF, Bakheet SA, El-Sherbeeny AM, Ibrahim KE, Alzahrani KS, Al-Harbi MM, Mahmood HM, Alqahtani F, Attia SM, Alotaibi MR. Therapeutic treatment with Ibrutinib attenuates imiquimod-induced psoriasis-like inflammation in mice through downregulation of oxidative and inflammatory mediators in neutrophils and dendritic cells. European Journal of Pharmacology. 173088. PMID 32234429 DOI: 10.1016/J.Ejphar.2020.173088  0.332
2020 Saleh T, Tyutyunyk-Massey L, H Patel N, K Cudjoe E, Alotaibi M, A Gewirtz D. Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy. International Journal of Molecular Sciences. 21. PMID 32093197 DOI: 10.3390/Ijms21041427  0.583
2019 Alotaibi MR, As Sobeai HM, Alaqil FA, Almutairi M, Alhazzani K, Sulaiman AAA, Isab AA, Hadal Alotaibi N. A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy. Saudi Pharmaceutical Journal : Spj : the Official Publication of the Saudi Pharmaceutical Society. 27: 1203-1209. PMID 31885480 DOI: 10.1016/J.Jsps.2019.10.003  0.466
2019 Imam F, Al-Harbi NO, Al-Harbi MM, Ansari MA, Al-Asmari AF, Ansari MN, Al-Anazi WA, Bahashwan S, Almutairi MM, Alshammari M, Khan MR, Alsaad AM, Alotaibi MR. Corrigendum to "Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways" [Pharmacol. Rep. 70 (2018) 993-1000]. Pharmacological Reports : Pr. 71: 1227. PMID 31669887 DOI: 10.1016/J.Pharep.2019.06.009  0.322
2019 Al-Hamamah MA, Alotaibi MR, Ahmad SF, Ansari MA, Attia MSM, Nadeem A, Bakheet SA, As Sobeai HM, Attia SM. Genetic and epigenetic alterations induced by the small-molecule panobinostat: A mechanistic study at the chromosome and gene levels. Dna Repair. 78: 70-80. PMID 30978576 DOI: 10.1016/J.Dnarep.2019.03.008  0.392
2019 Al-Mazroua HA, Alomar HA, Ahmad SF, Msa A, Nadeem A, Bakheet SA, Ams A, Alotaibi MR, Attia SM. Assessment of DNA repair efficiency in the inbred BTBR Ttf/J autism spectrum disorder mouse model exposed to gamma rays and treated with JNJ7777120. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 30959085 DOI: 10.1016/J.Pnpbp.2019.04.003  0.322
2019 Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, Henderson SC, Yakovlev V, Elmore LW, Toor A, Harada H, Reed J, Landry JW, Gewirtz DA. Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach Cancer Research. 79: 901-901. DOI: 10.1158/1538-7445.Am2019-901  0.715
2018 Imam F, Al-Harbi NO, Al-Harbi MM, Ansari MA, Al-Asmari AF, Ansari MN, Al-Anazi WA, Bahashwan S, Almutairi MM, Alshammari M, Khan MR, Alsaad AM, Alotaibi MR. Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways. Pharmacological Reports : Pr. 70: 993-1000. PMID 32002953 DOI: 10.1016/J.Pharep.2018.03.009  0.33
2018 Alzahrani KS, Nadeem A, Ahmad SF, Al-Harbi NO, Ibrahim KE, El-Sherbeeny AM, Alhoshani AR, Alshammari MA, Alotaibi MR, Al-Harbi MM. Inhibition of spleen tyrosine kinase attenuates psoriasis-like inflammation in mice through blockade of dendritic cell-Th17 inflammation axis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 111: 347-358. PMID 30593001 DOI: 10.1016/J.Biopha.2018.12.060  0.347
2018 Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, Henderson SC, Yakovlev V, Elmore LW, Toor A, Harada H, Reed J, Landry JW, Gewirtz DA. Tumor cell escape from therapy-induced senescence. Biochemical Pharmacology. PMID 30576620 DOI: 10.1016/J.Bcp.2018.12.013  0.692
2018 Xu J, Patel NH, Saleh T, Cudjoe EK, Alotaibi M, Wu Y, Lima S, Hawkridge AM, Gewirtz DA. Differential Radiation Sensitivity in p53 Wild-Type and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy. Radiation Research. PMID 30132722 DOI: 10.1667/Rr15099.1  0.714
2018 Attia SM, Al-Hamamah MA, Alotaibi MR, Harisa GI, Attia MM, Ahmad SF, Ansari MA, Nadeem A, Bakheet SA. Investigation of belinostat-induced genomic instability by molecular cytogenetic analysis and pathway-focused gene expression profiling. Toxicology and Applied Pharmacology. PMID 29733868 DOI: 10.1016/J.Taap.2018.05.002  0.426
2018 Alotaibi MR, Hassan ZK, Al-Rejaie SS, Alshammari MA, Almutairi MM, Alhoshani AR, Alanazi WA, Hafez MM, Al-Shabanah OA. Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing Asian Pacific Journal of Cancer Prevention : Apjcp. 19: 777-783. PMID 29582634 DOI: 10.22034/Apjcp.2018.19.3.777  0.409
2018 Al-Harbi NO, Nadeem A, Ahmad SF, Alotaibi MR, AlAsmari AF, Alanazi WA, Al-Harbi MM, El-Sherbeeny AM, Ibrahim KE. Short chain fatty acid, acetate ameliorates sepsis-induced acute kidney injury by inhibition of NADPH oxidase signaling in T cells. International Immunopharmacology. 58: 24-31. PMID 29544198 DOI: 10.1016/J.Intimp.2018.02.023  0.385
2018 Saleh T, Alotaibi MR, Kyte SL, Cudjoe EK, Kawale A, Xu J, Elsayed Z, Landry JW, Henderson SC, Yakovlev V, Elmore LW, Gewirtz DA. Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo Cancer Research. 78: 459-459. DOI: 10.1158/1538-7445.Am2018-459  0.71
2018 Xu J, Cudjoe EK, Saleh T, Patel N, Alotaibi M, Wu Y, Lima S, Gewirtz D. Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation Cancer Research. 78: 1326-1326. DOI: 10.1158/1538-7445.Am2018-1326  0.682
2017 Almutairi MM, Alanazi WA, Alshammari MA, Alotaibi MR, Alhoshani AR, Al-Rejaie SS, Hafez MM, Al-Shabanah OA. Neuro-protective effect of rutin against Cisplatin-induced neurotoxic rat model. Bmc Complementary and Alternative Medicine. 17: 472. PMID 28962559 DOI: 10.1186/S12906-017-1976-9  0.323
2017 Alhoshani AR, Hafez MM, Husain S, Al-Sheikh AM, Alotaibi MR, Al Rejaie SS, Alshammari MA, Almutairi MM, Al-Shabanah OA. Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats. Bmc Nephrology. 18: 194. PMID 28619064 DOI: 10.1186/S12882-017-0601-Y  0.337
2016 AL Shabanah OA, Alotaibi MR, Al Rejaie SS, Alhoshani AR, Almutairi MM, Alshammari MA, Hafez MM. Inhibitory Effect of Ginseng on Breast Cancer Cell Line Growth Via Up-Regulation of Cyclin Dependent Kinase Inhibitor, p21 and p53 Asian Pacific Journal of Cancer Prevention : Apjcp. 17: 4965-4971. PMID 28032724  0.359
2016 Gewirtz DA, Alotaibi M, Yakovlev VA, Povirk LF. Tumor Cell Recovery from Senescence Induced by Radiation with PARP Inhibition. Radiation Research. PMID 27588595 DOI: 10.1667/Rr14437.1  0.689
2016 Alotaibi M, Sharma K, Saleh T, Povirk LF, Hendrickson EA, Gewirtz DA. Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells. Radiation Research. PMID 26934368 DOI: 10.1667/Rr14202.1  0.785
2016 Alotaibi MR, Sharma K, Saleh T, Povirk L, Hendrickson E, Gewirtz D. Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition Cancer Research. 76: 2848-2848. DOI: 10.1158/1538-7445.Am2016-2848  0.78
2016 Saleh T, Thekkudan T, Alotaibi MR, Gewirtz DA. Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence Cancer Research. 76: 2846-2846. DOI: 10.1158/1538-7445.Am2016-2846  0.7
2015 Alotaibi MR, Povirk L, Gewirtz D. Abstract 993: The relationship between autophagy, senescence, and DNA repair Cancer Research. 75: 993-993. DOI: 10.1158/1538-7445.Am2015-993  0.612
2014 Sharma K, Le N, Alotaibi M, Gewirtz DA. Cytotoxic autophagy in cancer therapy. International Journal of Molecular Sciences. 15: 10034-51. PMID 24905404 DOI: 10.3390/Ijms150610034  0.774
2014 Emery SM, Alotaibi MR, Tao Q, Selley DE, Lichtman AH, Gewirtz DA. Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 348: 293-302. PMID 24259678 DOI: 10.1124/Jpet.113.205120  0.638
2014 Alotaibi MR, Gewirtz D, Povirk L. Abstract 2385: Involvement of autophagy and senescence in DNA repair in irradiated tumor cells Cancer Research. 74: 2385-2385. DOI: 10.1158/1538-7445.Am2014-2385  0.592
2013 Alotaibi MR, Asnake B, Di X, Beckman MJ, Durrant D, Simoni D, Baruchello R, Lee RM, Schwartz EL, Gewirtz DA. Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death. Biochemical Pharmacology. 86: 1688-98. PMID 24144631 DOI: 10.1016/J.Bcp.2013.10.007  0.77
2013 Biggers JW, Nguyen T, Di X, Gupton JT, Henderson SC, Emery SM, Alotaibi M, White KL, Brown R, Almenara J, Gewirtz DA. Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14. Cancer Chemotherapy and Pharmacology. 71: 441-55. PMID 23178952 DOI: 10.1007/S00280-012-2024-6  0.768
2013 Alotaibi MR. Abstract 1658: Cell death and growth arrest pathways mediating the actions of stilbene 5c in HCT-116 colon cancer cells and B16F10 melanoma cells. Cancer Research. 73: 1658-1658. DOI: 10.1158/1538-7445.Am2013-1658  0.585
2012 Alotaibi MR, Beckman MJ, Di X, Lee R, Gewirtz DA. Abstract 3957: Cell death and growth arrest pathways mediating the actions of stilbene 5C in HCT-116 colon cancer cells Cancer Research. 72: 3957-3957. DOI: 10.1158/1538-7445.Am2012-3957  0.769
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