| Year |
Citation |
Score |
| 2022 |
Friedlová N, Zavadil Kokáš F, Hupp TR, Vojtěšek B, Nekulová M. IFITM protein regulation and functions: Far beyond the fight against viruses. Frontiers in Immunology. 13: 1042368. PMID 36466909 DOI: 10.3389/fimmu.2022.1042368 |
0.308 |
|
| 2022 |
Padariya M, Jooste ML, Hupp T, Fåhraeus R, Vojtesek B, Vollrath F, Kalathiya U, Karakostis K. The Elephant Evolved p53 Isoforms that Escape MDM2-Mediated Repression and Cancer. Molecular Biology and Evolution. 39. PMID 35792674 DOI: 10.1093/molbev/msac149 |
0.414 |
|
| 2021 |
Salomao N, Karakostis K, Hupp T, Vollrath F, Vojtesek B, Fahraeus R. What do we need to know and understand about p53 to improve its clinical value? The Journal of Pathology. PMID 33826155 DOI: 10.1002/path.5677 |
0.353 |
|
| 2020 |
Bibi N, Hupp T, Kamal MA, Rashid S. Elucidation of PLK1 Linked Biomarkers in Oesophageal Cancer Cell Lines: A Step Towards Novel Signaling Pathways by p53 and PLK1- Linked Functions Crosstalk. Protein and Peptide Letters. PMID 32875973 DOI: 10.2174/0929866527999200901201837 |
0.416 |
|
| 2020 |
Faktor J, Grasso G, Zavadil F, Kurkowiak M, Mayordomo MY, Kote S, Singh A, Ruidong L, O'Neill JR, Muller P, Goodlett D, Vojtesek B, Hupp T. The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model. Biochimica Et Biophysica Acta. General Subjects. 129722. PMID 32866596 DOI: 10.1016/J.Bbagen.2020.129722 |
0.399 |
|
| 2019 |
Delom F, Mohtar MA, Hupp T, Fessart D. The AGR2 interactome. American Journal of Physiology. Cell Physiology. PMID 31644305 DOI: 10.1152/Ajpcell.00532.2018 |
0.384 |
|
| 2019 |
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, ... Hupp T, et al. Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation. Embo Molecular Medicine. PMID 31040128 DOI: 10.15252/Emmm.201810120 |
0.341 |
|
| 2019 |
Wang Q, Zhang X, Chen L, Weng S, Xia Y, Ye Y, Li K, Liao Z, Chen P, Alsamman K, Meng C, Stevens C, Hupp TR, Lin Y. Regulation of the Expression of DAPK1 by SUMO Pathway. Biomolecules. 9. PMID 30999631 DOI: 10.3390/biom9040151 |
0.304 |
|
| 2019 |
Bibi N, Niaz H, Hupp T, Kamal MA, Rashid S. Screening and Identification of PLK1-Polo Box binding peptides by high-throughput sequencing of phage-selected libraries. Protein and Peptide Letters. PMID 30887917 DOI: 10.2174/0929866526666190318101054 |
0.316 |
|
| 2019 |
Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Vojtesek B, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. Journal of Proteomics. PMID 30862565 DOI: 10.1016/J.Jprot.2019.02.012 |
0.306 |
|
| 2019 |
Nguyen MN, Sen N, Lin MY, Joseph TL, Vaz C, Tanavde V, Way L, Hupp TR, Verma CS, Madhusudhan MS. Discovering Putative Protein Targets of Small Molecules: A Study of the p53 Activator Nutlin. Journal of Chemical Information and Modeling. PMID 30794402 DOI: 10.1021/Acs.Jcim.8B00762 |
0.434 |
|
| 2018 |
Mohtar MA, Hernychova L, O'Neill R, Lawrence M, Murray E, Vojtesek B, Hupp TR. The sequence-specific peptide-binding activity of the protein sulfide isomerase AGR2 directs its' stable binding to the oncogenic receptor EpCAM. Molecular & Cellular Proteomics : McP. PMID 29339412 DOI: 10.1074/mcp.RA118.000573 |
0.304 |
|
| 2017 |
Muller P, Chan JM, Simoncik O, Fojta M, Lane DP, Hupp T, Vojtesek B. Evidence for allosteric effects on p53 oligomerization induced by phosphorylation. Protein Science : a Publication of the Protein Society. PMID 29124793 DOI: 10.1002/Pro.3344 |
0.596 |
|
| 2017 |
Landré V, Revi B, Mir MG, Verma C, Hupp TR, Gilbert N, Ball KL. Regulation of transcriptional activators by DNA-binding domain ubiquitination. Cell Death and Differentiation. PMID 28362432 DOI: 10.1038/Cdd.2017.42 |
0.434 |
|
| 2016 |
Way L, Faktor J, Dvorakova P, Nicholson J, Vojtesek B, Graham D, Ball KL, Hupp T. Rearrangement of Mitochondrial Pyruvate Dehydrogenase Subunit Dihydrolipoamide Dehydrogenase Protein-Protein Interactions by the MDM2 Ligand Nutlin-3. Proteomics. PMID 27273042 DOI: 10.1002/Pmic.201500501 |
0.426 |
|
| 2015 |
Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin. Chemical Science. 6: 3109-3116. PMID 28706685 DOI: 10.1039/c4sc03885a |
0.334 |
|
| 2015 |
Krejci A, Hupp TR, Lexa M, Vojtesek B, Muller P. Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets. Bioinformatics (Oxford, England). PMID 26342231 DOI: 10.1093/Bioinformatics/Btv522 |
0.345 |
|
| 2015 |
Dickinson ER, Jurneczko E, Nicholson J, Hupp TR, Zawacka-Pankau J, Selivanova G, Barran PE. The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors. Frontiers in Molecular Biosciences. 2: 39. PMID 26217671 DOI: 10.3389/Fmolb.2015.00039 |
0.401 |
|
| 2015 |
Marcar L, Ihrig B, Hourihan J, Bray SE, Quinlan PR, Jordan LB, Thompson AM, Hupp TR, Meek DW. MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4. Plos One. 10: e0127713. PMID 26001071 DOI: 10.1371/journal.pone.0127713 |
0.332 |
|
| 2015 |
Dickinson ER, Jurneczko E, Pacholarz KJ, Clarke DJ, Reeves M, Ball KL, Hupp T, Campopiano D, Nikolova PV, Barran PE. Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry. Analytical Chemistry. 87: 3231-8. PMID 25629302 DOI: 10.1021/Ac503720V |
0.337 |
|
| 2015 |
Fraser JA, Worrall EG, Lin Y, Landre V, Pettersson S, Blackburn E, Walkinshaw M, Muller P, Vojtesek B, Ball K, Hupp TR. Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis. Journal of Molecular Biology. 427: 1728-47. PMID 25543083 DOI: 10.1016/J.Jmb.2014.12.011 |
0.313 |
|
| 2014 |
Gray TA, Alsamman K, Murray E, Sims AH, Hupp TR. Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2. Molecular Biosystems. 10: 1409-25. PMID 24710632 DOI: 10.1039/c4mb00113c |
0.326 |
|
| 2014 |
Nicholson J, Scherl A, Way L, Blackburn EA, Walkinshaw MD, Ball KL, Hupp TR. A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2. Cellular Signalling. 26: 1243-57. PMID 24583282 DOI: 10.1016/j.cellsig.2014.02.011 |
0.329 |
|
| 2014 |
Dejeans N, Manié S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E. Addicted to secrete - novel concepts and targets in cancer therapy. Trends in Molecular Medicine. 20: 242-50. PMID 24456621 DOI: 10.1016/J.Molmed.2013.12.003 |
0.35 |
|
| 2014 |
Kofod-Olsen E, Pettersson S, Wallace M, Abduljabar AB, Oster B, Hupp T, Höllsberg P. Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization. Virology. 448: 33-42. PMID 24314634 DOI: 10.1016/J.Virol.2013.10.002 |
0.489 |
|
| 2013 |
Huart AS, Saxty B, Merritt A, Nekulova M, Lewis S, Huang Y, Vojtesek B, Kettleborough C, Hupp TR. A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway. Bioorganic & Medicinal Chemistry Letters. 23: 5578-85. PMID 24007918 DOI: 10.1016/j.bmcl.2013.08.046 |
0.311 |
|
| 2013 |
Hernychova L, Man P, Verma C, Nicholson J, Sharma CA, Ruckova E, Teo JY, Ball K, Vojtesek B, Hupp TR. Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometry. Proteomics. 13: 2512-25. PMID 23776060 DOI: 10.1002/Pmic.201300029 |
0.34 |
|
| 2013 |
Kofod-Olsen E, Møller JM, Schleimann MH, Bundgaard B, Bak RO, Øster B, Mikkelsen JG, Hupp T, Höllsberg P. Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B. Plos One. 8: e59223. PMID 23555634 DOI: 10.1371/Journal.Pone.0059223 |
0.427 |
|
| 2013 |
Morgan HP, O'Reilly FJ, Wear MA, O'Neill JR, Fothergill-Gilmore LA, Hupp T, Walkinshaw MD. M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5881-6. PMID 23530218 DOI: 10.1073/Pnas.1217157110 |
0.339 |
|
| 2013 |
Pettersson S, Sczaniecka M, McLaren L, Russell F, Gladstone K, Hupp T, Wallace M. Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway. The Biochemical Journal. 450: 523-36. PMID 23252402 DOI: 10.1042/Bj20121249 |
0.38 |
|
| 2013 |
Chevet E, Fessart D, Delom F, Mulot A, Vojtesek B, Hrstka R, Murray E, Gray T, Hupp T. Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development. Oncogene. 32: 2499-509. PMID 22945652 DOI: 10.1038/Onc.2012.346 |
0.395 |
|
| 2013 |
Scotcher J, Clarke DJ, MacKay CL, Hupp T, Sadler PJ, Langridge-Smith PRR. Redox regulation of tumour suppressor protein p53: Identification of the sites of hydrogen peroxide oxidation and glutathionylation Chemical Science. 4: 1257-1269. DOI: 10.1039/C2Sc21702C |
0.468 |
|
| 2012 |
Ponnuswamy A, Hupp T, Fåhraeus R. Concepts in MDM2 Signaling: Allosteric Regulation and Feedback Loops. Genes & Cancer. 3: 291-7. PMID 23150762 DOI: 10.1177/1947601912454140 |
0.527 |
|
| 2012 |
Nicholson J, Neelagandan K, Huart AS, Ball K, Molloy MP, Hupp T. An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis. Journal of Proteome Research. 11: 5464-78. PMID 23039052 DOI: 10.1021/Pr300698D |
0.447 |
|
| 2012 |
Morelli X, Hupp T. Searching for the Holy Grail; protein-protein interaction analysis and modulation. Embo Reports. 13: 877-9. PMID 22986552 DOI: 10.1038/Embor.2012.137 |
0.352 |
|
| 2012 |
Hupp TR, Hayward RL, Vojtesek B. Strategies for p53 reactivation in human sarcoma. Cancer Cell. 22: 283-5. PMID 22975370 DOI: 10.1016/j.ccr.2012.08.020 |
0.314 |
|
| 2012 |
Huart AS, MacLaine NJ, Narayan V, Hupp TR. Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth. Plos One. 7: e43391. PMID 22916255 DOI: 10.1371/journal.pone.0043391 |
0.385 |
|
| 2012 |
Robson AF, Hupp TR, Lickiss F, Ball KL, Faulds K, Graham D. Nanosensing protein allostery using a bivalent mouse double minute two (MDM2) assay. Proceedings of the National Academy of Sciences of the United States of America. 109: 8073-8. PMID 22556265 DOI: 10.1073/pnas.1116637109 |
0.349 |
|
| 2012 |
Gray TA, MacLaine NJ, Michie CO, Bouchalova P, Murray E, Howie J, Hrstka R, Maslon MM, Nenutil R, Vojtesek B, Langdon S, Hayward L, Gourley C, Hupp TR. Anterior Gradient-3: a novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models. Journal of Immunological Methods. 378: 20-32. PMID 22361111 DOI: 10.1016/J.Jim.2012.01.013 |
0.403 |
|
| 2012 |
Frame S, Aspinall C, O'Neil R, Hollick J, Taylor S, Hupp T, Blake D, Zheleva DI. Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization Cancer Research. 72: 2814-2814. DOI: 10.1158/1538-7445.Am2012-2814 |
0.402 |
|
| 2011 |
Clarke DJ, Murray E, Hupp T, Mackay CL, Langridge-Smith PR. Mapping a noncovalent protein-peptide interface by top-down FTICR mass spectrometry using electron capture dissociation. Journal of the American Society For Mass Spectrometry. 22: 1432-40. PMID 21953198 DOI: 10.1007/S13361-011-0155-3 |
0.407 |
|
| 2011 |
Hengel SM, Murray E, Langdon S, Hayward L, O'Donoghue J, Panchaud A, Hupp T, Goodlett DR. Data-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistance. Journal of Proteome Research. 10: 4567-78. PMID 21936522 DOI: 10.1021/Pr2004117 |
0.355 |
|
| 2011 |
Hollstein M, Hupp T. Chek2ing out the p53 pathway: can Puma lead the way? Cell Cycle (Georgetown, Tex.). 10: 1524. PMID 21478674 DOI: 10.4161/Cc.10.10.15514 |
0.397 |
|
| 2011 |
Scotcher J, Clarke DJ, Weidt SK, Mackay CL, Hupp TR, Sadler PJ, Langridge-Smith PR. Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry. Journal of the American Society For Mass Spectrometry. 22: 888-97. PMID 21472523 DOI: 10.1007/S13361-011-0088-X |
0.372 |
|
| 2011 |
Pang LY, Scott M, Hayward RL, Mohammed H, Whitelaw CB, Smith GC, Hupp TR. p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program. Cell Cycle (Georgetown, Tex.). 10: 932-50. PMID 21368573 |
0.376 |
|
| 2011 |
MacLaine NJ, Hupp TR. How phosphorylation controls p53. Cell Cycle (Georgetown, Tex.). 10: 916-21. PMID 21350334 DOI: 10.4161/cc.10.6.15076 |
0.401 |
|
| 2011 |
Narayan V, Halada P, Hernychová L, Chong YP, Žáková J, Hupp TR, Vojtesek B, Ball KL. A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1. The Journal of Biological Chemistry. 286: 14291-303. PMID 21245151 DOI: 10.1074/jbc.M110.204602 |
0.31 |
|
| 2011 |
Dastidar SG, Raghunathan D, Nicholson J, Hupp TR, Lane DP, Verma CS. Chemical states of the N-terminal "lid" of MDM2 regulate p53 binding: simulations reveal complexities of modulation. Cell Cycle (Georgetown, Tex.). 10: 82-9. PMID 21191186 DOI: 10.4161/Cc.10.1.14345 |
0.509 |
|
| 2011 |
Lin Y, Henderson P, Pettersson S, Satsangi J, Hupp T, Stevens C. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway. The Febs Journal. 278: 354-70. PMID 21134130 DOI: 10.1111/j.1742-4658.2010.07959.x |
0.343 |
|
| 2010 |
Marcar L, Maclaine NJ, Hupp TR, Meek DW. Mage-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin. Cancer Research. 70: 10362-70. PMID 21056992 DOI: 10.1158/0008-5472.CAN-10-1341 |
0.43 |
|
| 2010 |
Maslon MM, Hrstka R, Vojtesek B, Hupp TR. A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin. Journal of Molecular Biology. 404: 418-38. PMID 20888340 DOI: 10.1016/j.jmb.2010.09.035 |
0.339 |
|
| 2010 |
Fraser JA, Vojtesek B, Hupp TR. A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. Phosphorylation at SER269 in vivo is linked to inactivation of p53 function Journal of Biological Chemistry. 285: 37762-37772. PMID 20851891 DOI: 10.1074/jbc.M110.143099 |
0.412 |
|
| 2010 |
Fraser JA, Madhumalar A, Blackburn E, Bramham J, Walkinshaw MD, Verma C, Hupp TR. A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. A model in which phosphorylation at Ser269 induces a mutant conformation to p53 Journal of Biological Chemistry. 285: 37773-37786. PMID 20847049 DOI: 10.1074/Jbc.M110.143107 |
0.396 |
|
| 2010 |
Maslon MM, Hupp TR. Drug discovery and mutant p53. Trends in Cell Biology. 20: 542-55. PMID 20656489 DOI: 10.1016/j.tcb.2010.06.005 |
0.393 |
|
| 2010 |
Hrstka R, Nenutil R, Fourtouna A, Maslon MM, Naughton C, Langdon S, Murray E, Larionov A, Petrakova K, Muller P, Dixon MJ, Hupp TR, Vojtesek B. The pro-metastatic protein anterior gradient-2 predicts poor prognosis in tamoxifen-treated breast cancers. Oncogene. 29: 4838-47. PMID 20531310 DOI: 10.1038/Onc.2010.228 |
0.321 |
|
| 2010 |
Nicholson J, Hupp TR. The molecular dynamics of MDM2. Cell Cycle (Georgetown, Tex.). 9: 1878-81. PMID 20436290 DOI: 10.4161/cc.9.10.11597 |
0.33 |
|
| 2010 |
Worrall EG, Worrall L, Blackburn E, Walkinshaw M, Hupp TR. The effects of phosphomimetic lid mutation on the thermostability of the N-terminal domain of MDM2. Journal of Molecular Biology. 398: 414-28. PMID 20303977 DOI: 10.1016/j.jmb.2010.03.023 |
0.358 |
|
| 2010 |
Meek DW, Hupp TR. The regulation of MDM2 by multisite phosphorylation--opportunities for molecular-based intervention to target tumours? Seminars in Cancer Biology. 20: 19-28. PMID 19897041 DOI: 10.1016/j.semcancer.2009.10.005 |
0.404 |
|
| 2010 |
Lin Y, Hupp TR, Stevens C. Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death. The Febs Journal. 277: 48-57. PMID 19878313 DOI: 10.1111/j.1742-4658.2009.07411.x |
0.302 |
|
| 2009 |
Maclaine NJ, Hupp TR. The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway. Aging. 1: 490-502. PMID 20157532 DOI: 10.18632/aging.100047 |
0.372 |
|
| 2009 |
Huart AS, MacLaine NJ, Meek DW, Hupp TR. CK1alpha plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability. The Journal of Biological Chemistry. 284: 32384-94. PMID 19759023 DOI: 10.1074/jbc.M109.052647 |
0.374 |
|
| 2009 |
Worrall EG, Wawrzynow B, Worrall L, Walkinshaw M, Ball KL, Hupp TR. Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif. Journal of Chemical Biology. 2: 113-29. PMID 19568783 DOI: 10.1007/s12154-009-0019-5 |
0.373 |
|
| 2009 |
Lin Y, Stevens C, Harrison B, Pathuri S, Amin E, Hupp TR. The alternative splice variant of DAPK-1, s-DAPK-1, induces proteasome-independent DAPK-1 destabilization. Molecular and Cellular Biochemistry. 328: 101-7. PMID 19267229 DOI: 10.1007/s11010-009-0079-4 |
0.304 |
|
| 2009 |
Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL. A function for the RING finger domain in the allosteric control of MDM2 conformation and activity. The Journal of Biological Chemistry. 284: 11517-30. PMID 19188367 DOI: 10.1074/jbc.M809294200 |
0.313 |
|
| 2009 |
Stevens C, Lin Y, Harrison B, Burch L, Ridgway RA, Sansom O, Hupp T. Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling. The Journal of Biological Chemistry. 284: 334-44. PMID 18974095 DOI: 10.1074/Jbc.M805165200 |
0.415 |
|
| 2008 |
Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR. ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1. The Febs Journal. 275: 4875-86. PMID 18754770 DOI: 10.1111/j.1742-4658.2008.06627.x |
0.364 |
|
| 2008 |
MacLaine NJ, Oster B, Bundgaard B, Fraser JA, Buckner C, Lazo PA, Meek DW, Höllsberg P, Hupp TR. A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection. The Journal of Biological Chemistry. 283: 28563-73. PMID 18669630 DOI: 10.1074/jbc.M804433200 |
0.317 |
|
| 2008 |
Nelson L, Anderson S, Archibald AL, Rhind S, Lu ZH, Condie A, McIntyre N, Thompson J, Nenutil R, Vojtesek B, Whitelaw CBA, Little TJ, Hupp T. An animal model to evaluate the function and regulation of the adaptively evolving stress protein SEP53 in oesophageal bile damage responses Cell Stress and Chaperones. 13: 375-385. PMID 18465210 DOI: 10.1007/S12192-008-0037-1 |
0.345 |
|
| 2008 |
Lin Y, Stevens C, Hrstka R, Harrison B, Fourtouna A, Pathuri S, Vojtesek B, Hupp T. An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing. The Febs Journal. 275: 2574-84. PMID 18422656 DOI: 10.1111/J.1742-4658.2008.06404.X |
0.415 |
|
| 2008 |
Oster B, Bundgaard B, Hupp TR, Höllsberg P. Human herpesvirus 6B induces phosphorylation of p53 in its regulatory domain by a CK2- and p38-independent pathway. The Journal of General Virology. 89: 87-96. PMID 18089732 DOI: 10.1099/vir.0.83136-0 |
0.306 |
|
| 2007 |
Little TJ, Nelson L, Hupp T. Adaptive evolution of a stress response protein Plos One. 2. PMID 17925851 DOI: 10.1371/Journal.Pone.0001003 |
0.327 |
|
| 2007 |
Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M. MDM2 chaperones the p53 tumor suppressor. The Journal of Biological Chemistry. 282: 32603-12. PMID 17848574 DOI: 10.1074/Jbc.M702767200 |
0.526 |
|
| 2007 |
Din S, Lennon AM, Arnott ID, Hupp T, Satsangi J. Technology insight: the application of proteomics in gastrointestinal disease. Nature Clinical Practice. Gastroenterology & Hepatology. 4: 372-85. PMID 17607293 DOI: 10.1038/Ncpgasthep0872 |
0.306 |
|
| 2007 |
Finlan LE, Hupp TR. p63: the phantom of the tumor suppressor. Cell Cycle (Georgetown, Tex.). 6: 1062-71. PMID 17426453 DOI: 10.4161/cc.6.9.4162 |
0.34 |
|
| 2007 |
Craig AL, Chrystal JA, Fraser JA, Sphyris N, Lin Y, Harrison BJ, Scott MT, Dornreiter I, Hupp TR. The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members. Molecular and Cellular Biology. 27: 3542-55. PMID 17339337 DOI: 10.1128/MCB.01595-06 |
0.597 |
|
| 2007 |
Lin Y, Stevens C, Hupp T. Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. The Journal of Biological Chemistry. 282: 16792-802. PMID 17324927 DOI: 10.1074/Jbc.M611559200 |
0.412 |
|
| 2007 |
Fraser JA, Hupp TR. Chemical genetics approach to identify peptide ligands that selectively stimulate DAPK-1 kinase activity. Biochemistry. 46: 2655-73. PMID 17297916 DOI: 10.1021/bi061562j |
0.31 |
|
| 2007 |
Stevens C, Lin Y, Sanchez M, Amin E, Copson E, White H, Durston V, Eccles DM, Hupp T. A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis. The Journal of Biological Chemistry. 282: 13791-803. PMID 17244621 DOI: 10.1074/Jbc.M605649200 |
0.344 |
|
| 2006 |
Finlan LE, Nenutil R, Ibbotson SH, Vojtesek B, Hupp TR. CK2-site phosphorylation of p53 is induced in DeltaNp63 expressing basal stem cells in UVB irradiated human skin. Cell Cycle (Georgetown, Tex.). 5: 2489-94. PMID 17106255 DOI: 10.4161/cc.5.21.3393 |
0.392 |
|
| 2006 |
Wallace M, Worrall E, Pettersson S, Hupp TR, Ball KL. Dual-site regulation of MDM2 E3-ubiquitin ligase activity. Molecular Cell. 23: 251-63. PMID 16857591 DOI: 10.1016/j.molcel.2006.05.029 |
0.368 |
|
| 2006 |
Shimizu H, Saliba D, Wallace M, Finlan L, Langridge-Smith PR, Hupp TR. Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo. The Biochemical Journal. 397: 355-67. PMID 16579792 DOI: 10.1042/Bj20051521 |
0.411 |
|
| 2006 |
Cesková P, Chichger H, Wallace M, Vojtesek B, Hupp TR. On the mechanism of sequence-specific DNA-dependent acetylation of p53: the acetylation motif is exposed upon DNA binding. Journal of Molecular Biology. 357: 442-56. PMID 16438982 DOI: 10.1016/j.jmb.2005.12.026 |
0.35 |
|
| 2004 |
Dornan D, Eckert M, Wallace M, Shimizu H, Ramsay E, Hupp TR, Ball KL. Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53. Molecular and Cellular Biology. 24: 10083-98. PMID 15509808 DOI: 10.1128/MCB.24.22.10083-10098.2004 |
0.38 |
|
| 2004 |
Finlan L, Hupp TR. The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain. The Journal of Biological Chemistry. 279: 49395-405. PMID 15337767 DOI: 10.1074/jbc.M405974200 |
0.37 |
|
| 2004 |
Burch L, Shimizu H, Smith A, Patterson C, Hupp TR. Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein. Journal of Molecular Biology. 337: 129-45. PMID 15001357 DOI: 10.1016/J.Jmb.2004.01.017 |
0.398 |
|
| 2004 |
Burch LR, Scott M, Pohler E, Meek D, Hupp T. Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1. Journal of Molecular Biology. 337: 115-28. PMID 15001356 DOI: 10.1016/j.jmb.2003.10.081 |
0.343 |
|
| 2004 |
Pohler E, Craig AL, Cotton J, Lawrie L, Dillon JF, Ross P, Kernohan N, Hupp TR. The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage. Molecular & Cellular Proteomics : McP. 3: 534-47. PMID 14967811 DOI: 10.1074/mcp.M300089-MCP200 |
0.344 |
|
| 2004 |
Pospísilová S, Brázda V, Kucharíková K, Luciani MG, Hupp TR, Skládal P, Palecek E, Vojtesek B. Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2. The Biochemical Journal. 378: 939-47. PMID 14640983 DOI: 10.1042/BJ20030662 |
0.425 |
|
| 2004 |
Liem AA, Appleyard MV, O'Neill MA, Hupp TR, Chamberlain MP, Thompson AM. Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines. British Journal of Cancer. 88: 1281-4. PMID 12698197 DOI: 10.1038/sj.bjc.6600898 |
0.309 |
|
| 2003 |
Dornan D, Shimizu H, Burch L, Smith AJ, Hupp TR. The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53. Molecular and Cellular Biology. 23: 8846-61. PMID 14612423 |
0.393 |
|
| 2003 |
Craig A, Scott M, Burch L, Smith G, Ball K, Hupp T. Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain. Embo Reports. 4: 787-92. PMID 12897801 DOI: 10.1038/sj.embor.embor901 |
0.399 |
|
| 2003 |
Craig AL, Bray SE, Finlan LE, Kernohan NM, Hupp TR. Signaling to p53: the use of phospho-specific antibodies to probe for in vivo kinase activation. Methods in Molecular Biology (Clifton, N.J.). 234: 171-202. PMID 12824532 DOI: 10.1385/1-59259-408-5:171 |
0.345 |
|
| 2003 |
Achison M, Hupp TR. Hypoxia attenuates the p53 response to cellular damage. Oncogene. 22: 3431-40. PMID 12776195 DOI: 10.1038/sj.onc.1206434 |
0.36 |
|
| 2003 |
Lane DP, Hupp TR. Drug discovery and p53. Drug Discovery Today. 8: 347-55. PMID 12681938 DOI: 10.1016/S1359-6446(03)02669-2 |
0.506 |
|
| 2003 |
Dornan D, Shimizu H, Burch L, Smith AJ, Hupp TR. The Proline Repeat Domain of p53 Binds Directly to the Transcriptional Coactivator p300 and Allosterically Controls DNA-Dependent Acetylation of p53 Molecular and Cellular Biology. 23: 8846-8861. DOI: 10.1128/MCB.23.23.8846-8861.2003 |
0.393 |
|
| 2003 |
Dornan D, Shimizu H, Perkins ND, Hupp TR. DNA-dependent Acetylation of p53 by the Transcription Coactivator p300 Journal of Biological Chemistry. 278: 13431-13441. DOI: 10.1074/JBC.M211460200 |
0.327 |
|
| 2002 |
Dornan D, Shimizu H, Perkins ND, Hupp TR. DNA-dependent acetylation of p53 by the transcription coactivator p300. The Journal of Biological Chemistry. 278: 13431-41. PMID 12499368 DOI: 10.1074/jbc.M211460200 |
0.413 |
|
| 2002 |
Shimizu H, Burch LR, Smith AJ, Dornan D, Wallace M, Ball KL, Hupp TR. The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo. The Journal of Biological Chemistry. 277: 28446-58. PMID 11925449 DOI: 10.1074/jbc.M202296200 |
0.369 |
|
| 2001 |
Dornan D, Hupp TR. Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300. Embo Reports. 2: 139-44. PMID 11258706 DOI: 10.1093/embo-reports/kve025 |
0.404 |
|
| 2000 |
Blaydes JP, Luciani MG, Pospisilova S, Ball HM, Vojtesek B, Hupp TR. Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription. The Journal of Biological Chemistry. 276: 4699-708. PMID 11078726 DOI: 10.1074/jbc.M003485200 |
0.426 |
|
| 2000 |
Luciani MG, Hutchins JR, Zheleva D, Hupp TR. The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A. Journal of Molecular Biology. 300: 503-18. PMID 10884347 DOI: 10.1006/jmbi.2000.3830 |
0.391 |
|
| 2000 |
Webley K, Bond JA, Jones CJ, Blaydes JP, Craig A, Hupp T, Wynford-Thomas D. Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Molecular and Cellular Biology. 20: 2803-8. PMID 10733583 DOI: 10.1128/Mcb.20.8.2803-2808.2000 |
0.468 |
|
| 2000 |
Craig AL, Blaydes JP, Burch LR, Thompson AM, Hupp TR. Dephosphorylation of p53 at Ser20 after cellular exposure to low levels of non-ionizing radiation. Oncogene. 18: 6305-12. PMID 10597229 DOI: 10.1038/sj.onc.1203085 |
0.303 |
|
| 2000 |
HUPP TR, LANE DP, BALL KL. Strategies for manipulating the p53 pathway in the treatment of human cancer Biochemical Journal. 352: 1-17. DOI: 10.1042/Bj3520001 |
0.507 |
|
| 1999 |
Cohen PA, Hupp TR, Lane DP, Daniels DA. Biochemical characterization of different conformational states of the Sf9 cell-purified p53His175 mutant protein. Febs Letters. 463: 179-84. PMID 10601663 DOI: 10.1016/S0014-5793(99)01603-8 |
0.547 |
|
| 1999 |
Blaydes JP, Sparks A, Hupp TR. Activation of p53 protein function in response to cellular irradiation Methods in Molecular Biology (Clifton, N.J.). 113: 591-598. PMID 10443454 DOI: 10.1385/1-59259-675-4:591 |
0.343 |
|
| 1999 |
Bond JA, Webley K, Wyllie FS, Jones CJ, Craig A, Hupp T, Wynford-Thomas D. p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblasts. Oncogene. 18: 3788-92. PMID 10391688 DOI: 10.1038/sj.onc.1202733 |
0.389 |
|
| 1999 |
Hupp TR. Regulation of p53 protein function through alterations in protein-folding pathways. Cellular and Molecular Life Sciences : Cmls. 55: 88-95. PMID 10065154 DOI: 10.1007/s000180050272 |
0.451 |
|
| 1999 |
CRAIG AL, BURCH L, VOJTESEK B, MIKUTOWSKA J, THOMPSON A, HUPP TR. Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers Biochemical Journal. 342: 133. DOI: 10.1042/0264-6021:3420133 |
0.368 |
|
| 1998 |
Blaydes JP, Hupp TR. DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site. Oncogene. 17: 1045-52. PMID 9747884 DOI: 10.1038/SJ.ONC.1202014 |
0.357 |
|
| 1997 |
Mundt M, Hupp T, Fritsche M, Merkle C, Hansen S, Lane D, Groner B. Protein interactions at the carboxyl terminus of p53 result in the induction of its in vitro transactivation potential Oncogene. 15: 237-244. PMID 9244359 DOI: 10.1038/Sj.Onc.1201174 |
0.573 |
|
| 1997 |
Fourie AM, Hupp TR, Lane DP, Sang BC, Barbosa MS, Sambrook JF, Gething MJ. HSP70 binding sites in the tumor suppressor protein p53. The Journal of Biological Chemistry. 272: 19471-9. PMID 9235949 DOI: 10.1074/jbc.272.31.19471 |
0.557 |
|
| 1996 |
Hansen S, Midgley CA, Lane DP, Freeman BC, Morimoto RI, Hupp TR. Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70. The Journal of Biological Chemistry. 271: 30922-8. PMID 8940078 DOI: 10.1074/Jbc.271.48.30922 |
0.58 |
|
| 1996 |
Marszalek J, Zhang W, Hupp TR, Margulies C, Carr KM, Cherry S, Kaguni JM. Domains of DnaA protein involved in interaction with DnaB protein, and in unwinding the Escherichia coli chromosomal origin. The Journal of Biological Chemistry. 271: 18535-42. PMID 8702501 DOI: 10.1074/Jbc.271.31.18535 |
0.348 |
|
| 1996 |
Hansen S, Hupp TR, Lane DP. Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group. The Journal of Biological Chemistry. 271: 3917-24. PMID 8632013 DOI: 10.1074/Jbc.271.7.3917 |
0.582 |
|
| 1996 |
Kernohan NM, Hupp TR, Lane DP. Modification of an N-terminal regulatory domain of T antigen restores p53-T antigen complex formation in the absence of an essential metal ion cofactor. The Journal of Biological Chemistry. 271: 4954-60. PMID 8617769 DOI: 10.1074/Jbc.271.9.4954 |
0.469 |
|
| 1996 |
Lane D, Hupp T, Warbrick E, Picksley S, Sparks A, Farheus R, Paramio J, Ball K, Lain S, Glover D, Hall P. Regulating and replacing suppressor gene function with small synthetic molecules; design of an active synthetic suppressor protein Biochemical Society Transactions. 24: 592S-592S. DOI: 10.1042/Bst024592Sa |
0.433 |
|
| 1995 |
Hupp TR, Lane DP. Allosteric activation of latent p53 tetramers. Current Biology : Cb. 4: 865-75. PMID 7850419 DOI: 10.1016/S0960-9822(00)00195-0 |
0.59 |
|
| 1995 |
Lane DP, Lu X, Hupp T, Hall PA. The role of the p53 protein in the apoptotic response. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 277-80. PMID 7846126 DOI: 10.1098/Rstb.1994.0106 |
0.568 |
|
| 1995 |
Lane DP, Midgley CA, Hupp TR, Lu X, Vojtesek B, Picksley SM. On the regulation of the p53 tumour suppressor, and its role in the cellular response to DNA damage. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 347: 83-7. PMID 7746859 DOI: 10.1098/Rstb.1995.0013 |
0.538 |
|
| 1995 |
Hupp TR, Lane DP. Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner. The Journal of Biological Chemistry. 270: 18165-74. PMID 7629129 DOI: 10.1074/Jbc.270.30.18165 |
0.557 |
|
| 1995 |
Hupp TR, Lane DP. Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases. Cold Spring Harbor Symposia On Quantitative Biology. 59: 195-206. PMID 7587070 DOI: 10.1101/SQB.1994.059.01.024 |
0.593 |
|
| 1995 |
Hupp TR, Sparks A, Lane DP. Small peptides activate the latent sequence-specific DNA binding function of p53 Cell. 83: 237-245. PMID 7585941 DOI: 10.1016/0092-8674(95)90165-5 |
0.554 |
|
| 1995 |
Cox L, Hupp T, Midgley C, Lane D. A direct effect of activated human p53 on nuclear DNA replication. The Embo Journal. 14: 2099-2105. DOI: 10.1002/J.1460-2075.1995.Tb07201.X |
0.566 |
|
| 1994 |
Picksley SM, Hupp TR, Lu X, Midgley CA, Vojtesek B, Lane DP. Regulation of p53 protein expression in human cancer Cancer Genetics and Cytogenetics. 77: 153. DOI: 10.1016/0165-4608(94)90250-X |
0.497 |
|
| 1993 |
Lane DP, Midgley C, Hupp T. Tumour suppressor genes and molecular chaperones. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 339: 369-72; discussion 3. PMID 8493291 DOI: 10.1098/Rstb.1993.0036 |
0.538 |
|
| 1993 |
Hupp TR, Meek DW, Midgley CA, Lane DP. Activation of the cryptic DNA binding function of mutant forms of p53. Nucleic Acids Research. 21: 3167-74. PMID 8341590 DOI: 10.1093/Nar/21.14.3167 |
0.548 |
|
| 1992 |
Hupp TR, Meek DW, Midgley CA, Lane DP. Regulation of the specific DNA binding function of p53. Cell. 71: 875-86. PMID 1423635 DOI: 10.1016/0092-8674(92)90562-Q |
0.57 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2001 |
Ball HL, Hupp TR, Ziyaie D, Purdie CA, Kernohan NM, Thompson AM. Differential p53 protein expression in breast cancer fine needle aspirates: The potential for in vivo monitoring British Journal of Cancer. 85: 1102-1105. PMID 11710820 DOI: 10.1054/bjoc.2001.2064 |
0.3 |
|
| 2008 |
Stevens C, Hupp TR. Novel insights into DAPK autophagic signalling using peptide aptamer combinatorial protein-interaction screens. Autophagy. 4: 531-3. PMID 18376136 |
0.298 |
|
| 2013 |
Gray TA, Murray E, Nowicki MW, Remnant L, Scherl A, Muller P, Vojtesek B, Hupp TR. Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein. Protein Science : a Publication of the Protein Society. 22: 1266-78. PMID 23780840 DOI: 10.1002/pro.2299 |
0.297 |
|
| 2018 |
Yuan M, McNae IW, Chen Y, Blackburn EA, Wear MA, Michels PAM, Fothergill-Gilmore LA, Hupp T, Walkinshaw MD. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor. The Biochemical Journal. PMID 29748232 DOI: 10.1042/Bcj20180171 |
0.293 |
|
| 2020 |
Li R, Zatloukalova P, Muller P, Gil-Mir M, Kote S, Wilkinson S, Kemp AJ, Hernychova L, Wang Y, Ball KL, Tao K, Hupp T, Vojtesek B. The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276. Cellular & Molecular Biology Letters. 25: 41. PMID 32874188 DOI: 10.1186/S11658-020-00233-W |
0.292 |
|
| 2005 |
Finlan LE, Kernohan NM, Thomson G, Beattie PE, Hupp TR, Ibbotson SH. Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo. The British Journal of Dermatology. 153: 1001-10. PMID 16225614 DOI: 10.1111/j.1365-2133.2005.06922.x |
0.289 |
|
| 2004 |
Craig AL, Hupp TR. The regulation of CHK2 in human cancer. Oncogene. 23: 8411-8. PMID 15361833 DOI: 10.1038/sj.onc.1208035 |
0.289 |
|
| 2013 |
Rosenbaum J, Baek SH, Dutta A, Houry WA, Huber O, Hupp TR, Matias PM. The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape. Science Signaling. 6: mr1. PMID 23482663 DOI: 10.1126/Scisignal.2003906 |
0.288 |
|
| 1993 |
Hupp T, Kaguni J. Activation of mutant forms of DnaA protein of Escherichia coli by DnaK and GrpE proteins occurs prior to DNA replication Journal of Biological Chemistry. 268: 13143-13150. DOI: 10.1016/s0021-9258(19)38630-2 |
0.281 |
|
| 2004 |
Ziyaie D, Hupp TR, Thompson AM. P53 and breast cancer. Breast (Edinburgh, Scotland). 9: 239-46. PMID 14732173 DOI: 10.1054/BRST.2000.0199 |
0.281 |
|
| 2008 |
Harrison B, Kraus M, Burch L, Stevens C, Craig A, Gordon-Weeks P, Hupp TR. DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. The Journal of Biological Chemistry. 283: 9999-10014. PMID 18195017 DOI: 10.1074/Jbc.M706040200 |
0.279 |
|
| 2016 |
Clarke DJ, Murray E, Faktor J, Mohtar A, Vojtesek B, MacKay CL, Smith PL, Hupp TR. Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond. Biochimica Et Biophysica Acta. PMID 26876500 DOI: 10.1016/j.bbapap.2016.02.011 |
0.278 |
|
| 2022 |
Gómez-Herranz M, Faktor J, Yébenes Mayordomo M, Pilch M, Nekulova M, Hernychova L, Ball KL, Vojtesek B, Hupp TR, Kote S. Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer. Biomolecules. 12. PMID 36008984 DOI: 10.3390/biom12081090 |
0.277 |
|
| 2022 |
Singh A, Padariya M, Faktor J, Kote S, Mikac S, Dziadosz A, Lam TW, Brydon J, Wear MA, Ball KL, Hupp T, Sznarkowska A, Vojtesek B, Kalathiya U. Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach. Scientific Reports. 12: 19422. PMID 36371414 DOI: 10.1038/s41598-022-21393-z |
0.277 |
|
| 2019 |
Bibi N, Rashid S, Nicholson J, Malloy M, O'Neill R, Blake D, Hupp T. An integrative "omics" approach, for identification of bona fides PLK1 associated biomarker in Oesophgeal adenocarcinoma. Current Cancer Drug Targets. PMID 30747067 DOI: 10.2174/1568009619666190211113722 |
0.271 |
|
| 2014 |
O'Neill R, Pak H, Nekulova M, Pairo-Castineira E, Save V, Paterson-Brown S, Scherl A, Vojtesek B, Overton I, Hupp T. A novel strategy to exploit metabolic dysregulation in oesophageal adenocarcinoma abolishes cancer cell proliferation British Journal of Surgery. 101: 3-4. DOI: 10.1002/Bjs.9508 |
0.269 |
|
| 2008 |
Pang LY, Hupp TR. Protein kinases coordinately regulate the p53: Delta Np63 alpha axis after DNA damage. Cell Cycle (Georgetown, Tex.). 7: 2779-80. PMID 18797190 DOI: 10.4161/cc.7.18.6891 |
0.269 |
|
| 2008 |
Fourtouna A, Hupp T. Cellular localization of the proto-oncogenic p53 inhibitor AGR2 protein in breast cancer Breast Cancer Research. 10. DOI: 10.1186/bcr1898 |
0.266 |
|
| 2019 |
Gómez-Herranz M, Nekulova M, Faktor J, Hernychova L, Kote S, Sinclair EH, Nenutil R, Vojtesek B, Ball KL, Hupp TR. The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis. Cellular Signalling. 60: 39-56. PMID 30951861 DOI: 10.1016/j.cellsig.2019.03.024 |
0.266 |
|
| 2015 |
Brychtova V, Mohtar A, Vojtesek B, Hupp TR. Mechanisms of anterior gradient-2 regulation and function in cancer. Seminars in Cancer Biology. 33: 16-24. PMID 25937245 DOI: 10.1016/j.semcancer.2015.04.005 |
0.26 |
|
| 2013 |
Hrstka R, Murray E, Brychtova V, Fabian P, Hupp TR, Vojtesek B. Identification of an AKT-dependent signalling pathway that mediates tamoxifen-dependent induction of the pro-metastatic protein anterior gradient-2. Cancer Letters. 333: 187-93. PMID 23354592 DOI: 10.1016/j.canlet.2013.01.034 |
0.259 |
|
| 2007 |
Murray E, McKenna EO, Burch LR, Dillon J, Langridge-Smith P, Kolch W, Pitt A, Hupp TR. Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2. Biochemistry. 46: 13742-51. PMID 17994709 DOI: 10.1021/bi7008739 |
0.257 |
|
| 2016 |
Beirão BC, Raposo T, Jain S, Hupp T, Argyle DJ. Challenges and opportunities for monoclonal antibody therapy in veterinary oncology. Veterinary Journal (London, England : 1997). 218: 40-50. PMID 27938708 DOI: 10.1016/J.Tvjl.2016.11.005 |
0.255 |
|
| 2002 |
Nicoll G, Crichton DN, McDowell HE, Kernohan N, Hupp TR, Thompson AM. Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer. British Journal of Cancer. 85: 1878-82. PMID 11747329 DOI: 10.1054/bjoc.2001.2163 |
0.25 |
|
| 2019 |
Kote S, Faktor J, Dapic I, Mayordomo MY, Kocikowski M, Kagansky A, Goodlett D, Vojtesek B, Hupp T, Wilcockson D, Piper R. Analysis of venom sac constituents from the solitary, hunting wasp Cerceris rybyensis. Toxicon : Official Journal of the International Society On Toxinology. PMID 31352010 DOI: 10.1016/J.Toxicon.2019.07.012 |
0.25 |
|
| 1994 |
Hupp TR, Keasling JD, Cooper S, Kaguni JM. Synthesis of DnaK protein during the division cycle of Escherichia coli. Research in Microbiology. 145: 99-109. PMID 8090998 DOI: 10.1016/0923-2508(94)90003-5 |
0.249 |
|
| 2006 |
Darragh J, Hunter M, Pohler E, Nelson L, Dillon JF, Nenutil R, Vojtesek B, Ross PE, Kernohan N, Hupp TR. The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury. The Febs Journal. 273: 1930-47. PMID 16640557 DOI: 10.1111/j.1742-4658.2006.05206.x |
0.248 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Hupp TR, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.248 |
|
| 2018 |
Parys M, Nekulová M, Vojtěšek B, Faktor J, Lima A, Hupp T. Abstract LB-115: Tumor intrinsic PD-1/PD-L1 signalling induces mesenchymal to epithelial transition in canine osteosarcoma cells Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-115 |
0.248 |
|
| 2021 |
Sicari D, Centonze FG, Pineau R, Le Reste PJ, Negroni L, Chat S, Mohtar MA, Thomas D, Gillet R, Hupp T, Chevet E, Igbaria A. Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors. Embo Reports. e51412. PMID 33710763 DOI: 10.15252/embr.202051412 |
0.247 |
|
| 2019 |
Wang YJ, Pietrzak K, Kocikowski M, Argyle D, Hupp T, Parys M. Abstract 3972: Investigation of tumor intrinsic PD1/PD-L1 in canine urothelial carcinomas as a spontaneous translational model for human invasive bladder cancer Cancer Research. 79: 3972-3972. DOI: 10.1158/1538-7445.Am2019-3972 |
0.247 |
|
| 2019 |
Kalathiya U, Padariya M, Pawlicka K, Verma CS, Houston D, Hupp TR, Alfaro JA. Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1. International Journal of Molecular Sciences. 20. PMID 31718065 DOI: 10.3390/ijms20225644 |
0.245 |
|
| 2015 |
Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin Chemical Science. 6: 3109-3116. DOI: 10.1039/c4sc03885a |
0.244 |
|
| 2018 |
Mohtar MA, Low TY, Vojtesek B, Jamal R, Hupp T. The development of a synthetic scFv monoclonal antibody targeting pro-oncogenic AGR2 Frontiers in Pharmacology. 9. DOI: 10.3389/Conf.Fphar.2018.63.00128 |
0.241 |
|
| 2008 |
Mackay CL, Ramsahoye B, Burgess K, Cook K, Weidt S, Creanor J, Harrison D, Langridge-Smith P, Hupp T, Hayward L. Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. Analytical Chemistry. 80: 4147-53. PMID 18457408 DOI: 10.1021/Ac702452D |
0.241 |
|
| 1993 |
Hupp T, Kaguni J. Activation of DnaA5 protein by GrpE and DnaK heat shock proteins in initiation of DNA replication in Escherichia coli Journal of Biological Chemistry. 268: 13137-13142. DOI: 10.1016/s0021-9258(19)38629-6 |
0.241 |
|
| 2000 |
HUPP TR, LANE DP, BALL KL. Strategies for manipulating the p53 pathway in the treatment of human cancer Biochemical Journal. 352: 1. DOI: 10.1042/0264-6021:3520001 |
0.239 |
|
| 1999 |
MacCallum DE, Hupp TR. Induction of p53 protein as a marker for ionizing radiation exposure in vivo. Methods in Molecular Biology (Clifton, N.J.). 113: 583-9. PMID 10443453 DOI: 10.1385/1-59259-675-4:583 |
0.239 |
|
| 2010 |
Craig AL, Holcakova J, Finlan LE, Nekulova M, Hrstka R, Gueven N, DiRenzo J, Smith G, Hupp TR, Vojtesek B. DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Molecular Cancer. 9: 195. PMID 20663147 DOI: 10.1186/1476-4598-9-195 |
0.236 |
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| 2022 |
Padariya M, Daniels A, Tait-Burkard C, Hupp T, Kalathiya U. Self-derived peptides from the SARS-CoV-2 spike glycoprotein disrupting shaping and stability of the homotrimer unit. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 151: 113190. PMID 35643065 DOI: 10.1016/j.biopha.2022.113190 |
0.236 |
|
| 2021 |
Kalathiya U, Padariya M, Faktor J, Coyaud E, Alfaro JA, Fahraeus R, Hupp TR, Goodlett DR. Interfaces with Structure Dynamics of the Workhorses from Cells Revealed through Cross-Linking Mass Spectrometry (CLMS). Biomolecules. 11. PMID 33806612 DOI: 10.3390/biom11030382 |
0.235 |
|
| 2020 |
Katarzyna D, Kocikowski M, Vojtesek B, Argyle D, Lisowska M, Hupp T, Parys M. Abstract 5637: Investigating tumor intrinsic PD-1/PD-L1 signaling in canine osteosarcoma cell lines as a spontaneous model for human disease Immunology. DOI: 10.1158/1538-7445.Am2020-5637 |
0.23 |
|
| 2000 |
Blaydes JP, Vojtesek B, Bloomberg GB, Hupp TR. The development and use of phospho-specific antibodies to study protein phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 99: 177-89. PMID 10909085 DOI: 10.1385/1-59259-054-3:177 |
0.222 |
|
| 2007 |
Hupp TR, Walkinshaw M. Multienzyme assembly of a p53 transcription complex. Nature Structural & Molecular Biology. 14: 885-7. PMID 17912258 DOI: 10.1038/nsmb1007-885 |
0.221 |
|
| 2009 |
Clyde RG, Craig AL, de Breed L, Bown JL, Forrester L, Vojtesek B, Smith G, Hupp T, Crawford J. A novel ataxia-telangiectasia mutated autoregulatory feedback mechanism in murine embryonic stem cells. Journal of the Royal Society, Interface / the Royal Society. 6: 1167-77. PMID 19324671 DOI: 10.1098/rsif.2008.0538 |
0.221 |
|
| 2021 |
Kalathiya U, Padariya M, Fahraeus R, Chakraborti S, Hupp TR. Multivalent Display of SARS-CoV-2 Spike (RBD Domain) of COVID-19 to Nanomaterial, Protein Ferritin Nanocages. Biomolecules. 11. PMID 33671255 DOI: 10.3390/biom11020297 |
0.216 |
|
| 2020 |
Kocikowski M, Dziubek K, Vojtesek B, Argyle D, Hupp T, Parys M. Abstract 2234: Development of caninized monoclonal antibodies against PD1 Immunology. DOI: 10.1158/1538-7445.Am2020-2234 |
0.215 |
|
| 2021 |
Padariya M, Sznarkowska A, Kote S, Gómez-Herranz M, Mikac S, Pilch M, Alfaro J, Fahraeus R, Hupp T, Kalathiya U. Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes. Biomolecules. 11. PMID 33922087 DOI: 10.3390/biom11050622 |
0.209 |
|
| 2014 |
Huang Y, Chen L, Guo L, Hupp TR, Lin Y. Evaluating DAPK as a therapeutic target. Apoptosis : An International Journal On Programmed Cell Death. 19: 371-86. PMID 24305735 DOI: 10.1007/s10495-013-0919-2 |
0.207 |
|
| 2023 |
Al Shboul S, Boyle S, Singh A, Saleh T, Alrjoub M, Abu Al Karsaneh O, Mryyian A, Dawoud R, Gul S, Abu Baker S, Ball K, Hupp T, Brennan PM. FISH analysis reveals CDKN2A and IFNA14 co-deletion is heterogeneous and is a prominent feature of glioblastoma. Brain Tumor Pathology. PMID 38097874 DOI: 10.1007/s10014-023-00473-6 |
0.203 |
|
| 2018 |
Gu X, Coates PJ, Boldrup L, Wang L, Krejci A, Hupp T, Fahraeus R, Norberg-Spaak L, Sgaramella N, Wilms T, Nylander K. Copy number variation: a prognostic marker for young patients with squamous cell carcinoma of the oral tongue. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. PMID 30357923 DOI: 10.1111/Jop.12792 |
0.202 |
|
| 2010 |
Hupp TR. Death-associated protein kinase (DAPK) and signal transduction. The Febs Journal. 277: 47. PMID 19878314 DOI: 10.1111/j.1742-4658.2009.07410.x |
0.201 |
|
| 2022 |
Blay V, Gailiunaite S, Lee CY, Chang HY, Hupp T, Houston DR, Chi P. Comparison of ATP-binding pockets and discovery of homologous recombination inhibitors. Bioorganic & Medicinal Chemistry. 70: 116923. PMID 35841829 DOI: 10.1016/j.bmc.2022.116923 |
0.201 |
|
| 2021 |
Weke K, Singh A, Uwugiaren N, Alfaro JA, Wang T, Hupp TR, O'Neill JR, Vojtesek B, Goodlett DR, Williams SM, Zhou M, Kelly RT, Zhu Y, Dapic I. MicroPOTS Analysis of Barrett's Esophageal Cell Line Models Identifies Proteomic Changes after Physiologic and Radiation Stress. Journal of Proteome Research. PMID 33491460 DOI: 10.1021/acs.jproteome.0c00629 |
0.2 |
|
| 2021 |
Mikac S, Rychłowski M, Dziadosz A, Szabelska-Beresewicz A, Fahraeus R, Hupp T, Sznarkowska A. Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells. Antioxidants (Basel, Switzerland). 10. PMID 34063559 DOI: 10.3390/antiox10050786 |
0.2 |
|
| 2020 |
Beirão BCB, Raposo TP, Imamura LM, Ingberman M, Hupp T, Vojtěšek B, Argyle DJ. A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis. Antibody Therapeutics. 3: 193-204. PMID 33937625 DOI: 10.1093/abt/tbaa018 |
0.196 |
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| 2022 |
Weke K, Kote S, Faktor J, Al Shboul S, Uwugiaren N, Brennan PM, Goodlett DR, Hupp TR, Dapic I. DIA-MS proteome analysis of formalin-fixed paraffin-embedded glioblastoma tissues. Analytica Chimica Acta. 1204: 339695. PMID 35397901 DOI: 10.1016/j.aca.2022.339695 |
0.187 |
|
| 2021 |
Al Shboul S, Curran OE, Alfaro JA, Lickiss F, Nita E, Kowalski J, Naji F, Nenutil R, Ball KL, Krejcir R, Vojtesek B, Hupp TR, Brennan PM. Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival. Life Science Alliance. 4. PMID 34645618 DOI: 10.26508/lsa.202101054 |
0.186 |
|
| 2021 |
Padariya M, Fahraeus R, Hupp T, Kalathiya U. Molecular Determinants and Specificity of mRNA with Alternatively-Spliced UPF1 Isoforms, Influenced by an Insertion in the 'Regulatory Loop'. International Journal of Molecular Sciences. 22. PMID 34884553 DOI: 10.3390/ijms222312744 |
0.183 |
|
| 2017 |
O'Neill JR, Pak HS, Pairo-Castineira E, Save V, Paterson-Brown S, Nenutil R, Vojtěšek B, Overton I, Scherl A, Hupp TR. Quantitative shotgun proteomics unveils candidate novel oesophageal adenocarcinoma-specific proteins. Molecular & Cellular Proteomics : McP. PMID 28336725 DOI: 10.1074/mcp.M116.065078 |
0.182 |
|
| 2022 |
Chevet E, Bassal F, Beq S, Bonhomme B, Boisteau E, Calloch J, Cazals-Hatem D, Delom F, Fessart D, Evrard S, Hrstka R, Hupp T, Lièvre A, Louis E, Mariau J, et al. AGR2 protein expression in colorectal tumour epithelialcompartment. Gut. PMID 36591613 DOI: 10.1136/gutjnl-2022-328739 |
0.178 |
|
| 2021 |
Bibi N, Farid A, Gul S, Ali J, Amin F, Kalthiya U, Hupp T. Drug repositioning against COVID-19: a first line treatment. Journal of Biomolecular Structure & Dynamics. 1-15. PMID 34519259 DOI: 10.1080/07391102.2021.1977698 |
0.178 |
|
| 2021 |
Dias C, Nita E, Faktor J, Tynan AC, Hernychova L, Vojtesek B, Nylandsted J, Hupp TR, Kunath T, Ball KL. CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity. Iscience. 24: 102878. PMID 34401662 DOI: 10.1016/j.isci.2021.102878 |
0.171 |
|
| 2021 |
Białobrzeska W, Dziąbowska K, Lisowska M, Mohtar MA, Muller P, Vojtesek B, Krejcir R, O'Neill R, Hupp TR, Malinowska N, Bięga E, Bigus D, Cebula Z, Pala K, Czaczyk E, et al. An Ultrasensitive Biosensor for Detection of Femtogram Levels of the Cancer Antigen AGR2 Using Monoclonal Antibody Modified Screen-Printed Gold Electrodes. Biosensors. 11. PMID 34200338 DOI: 10.3390/bios11060184 |
0.168 |
|
| 2014 |
Murray E, Hernychová L, Scigelova M, Ho J, Nekulova M, O'Neill JR, Nenutil R, Vesely K, Dundas SR, Dhaliwal C, Henderson H, Hayward RL, Salter DM, Vojtěšek B, Hupp TR. Quantitative proteomic profiling of pleomorphic human sarcoma identifies CLIC1 as a dominant pro-oncogenic receptor expressed in diverse sarcoma types. Journal of Proteome Research. 13: 2543-59. PMID 24661138 DOI: 10.1021/pr4010713 |
0.165 |
|
| 2016 |
Jain S, Aresu L, Comazzi S, Shi J, Worrall E, Clayton J, Humphries W, Hemmington S, Davis P, Murray E, Limeneh AA, Ball K, Ruckova E, Muller P, Vojtesek B, ... ... Hupp TR, et al. The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine. Plos One. 11: e0148366. PMID 26894679 DOI: 10.1371/journal.pone.0148366 |
0.165 |
|
| 2020 |
Kalathiya U, Padariya M, Mayordomo M, Lisowska M, Nicholson J, Singh A, Baginski M, Fahraeus R, Carragher N, Ball K, Haas J, Daniels A, Hupp TR, Alfaro JA. Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site. Journal of Clinical Medicine. 9. PMID 32422996 DOI: 10.3390/jcm9051473 |
0.163 |
|
| 2003 |
Shimizu H, Hupp TR. Intrasteric regulation of MDM2. Trends in Biochemical Sciences. 28: 346-9. PMID 12877998 DOI: 10.1016/S0968-0004(03)00140-3 |
0.162 |
|
| 2014 |
Pang LY, Gatenby EL, Kamida A, Whitelaw BA, Hupp TR, Argyle DJ. Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. Plos One. 9: e83144. PMID 24416158 DOI: 10.1371/journal.pone.0083144 |
0.161 |
|
| 2008 |
Groome M, Lindsay J, Ross PE, Cotton JP, Hupp TR, Dillon JF. Use of oesophageal stress response proteins as potential biomarkers in the screening for Barrett's oesophagus. European Journal of Gastroenterology & Hepatology. 20: 961-5. PMID 18787461 DOI: 10.1097/MEG.0b013e3282ffd9bd |
0.16 |
|
| 2005 |
Beattie PE, Finlan LE, Kernohan NM, Thomson G, Hupp TR, Ibbotson SH. The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21. The British Journal of Dermatology. 152: 1001-8. PMID 15888160 DOI: 10.1111/j.1365-2133.2005.06557.x |
0.159 |
|
| 2022 |
Lisowska M, Lickiss F, Gil-Mir M, Huart AS, Trybala Z, Way L, Hernychova L, Krejci A, Muller P, Krejcir R, Zhukow I, Jurczak P, Rodziewicz-Motowidło S, Ball K, Vojtesek B, ... Hupp T, et al. Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the ubiquitin transfer cascade. Frontiers in Microbiology. 13: 875556. PMID 36532480 DOI: 10.3389/fmicb.2022.875556 |
0.158 |
|
| 2021 |
Pirog A, Faktor J, Urban-Wojciuk Z, Kote S, Chruściel E, Arcimowicz Ł, Marek-Trzonkowska N, Vojtesek B, Hupp TR, Al Shboul S, Brennan PM, Smoleński RT, Goodlett DR, Dapic I. Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples. Talanta. 233: 122568. PMID 34215064 DOI: 10.1016/j.talanta.2021.122568 |
0.157 |
|
| 2021 |
Padariya M, Kote S, Mayordomo M, Dapic I, Alfaro J, Hupp T, Fahraeus R, Kalathiya U. Structural determinants of peptide-dependent TAP1-TAP2 transit passage targeted by viral proteins and altered by cancer-associated mutations. Computational and Structural Biotechnology Journal. 19: 5072-5091. PMID 34589184 DOI: 10.1016/j.csbj.2021.09.006 |
0.155 |
|
| 2021 |
Kurkowiak M, Grasso G, Faktor J, Scheiblecker L, Winniczuk M, Mayordomo MY, O'Neill JR, Oster B, Vojtesek B, Al-Saadi A, Marek-Trzonkowska N, Hupp TR. An integrated DNA and RNA variant detector identifies a highly conserved three base exon in the kinase locus. Rna Biology. 1-20. PMID 34190025 DOI: 10.1080/15476286.2021.1932345 |
0.15 |
|
| 2000 |
Hupp TR. Development of physiological models to study stress protein responses. Methods in Molecular Biology (Clifton, N.J.). 99: 465-83. PMID 10909099 DOI: 10.1385/1-59259-054-3:465 |
0.149 |
|
| 2023 |
Bedran G, Gasser HC, Weke K, Wang T, Bedran D, Laird A, Battail C, Zanzotto FM, Pesquita C, Axelson H, Rajan A, Harrison DJ, Palkowski A, Pawlik M, Parys M, ... ... Hupp TR, et al. The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides. Cancer Immunology Research. PMID 36961404 DOI: 10.1158/2326-6066.CIR-22-0621 |
0.148 |
|
| 1993 |
Hupp T, Kaguni J. DnaA5 protein is thermolabile in initiation of replication from the chromosomal origin of Escherichia coli Journal of Biological Chemistry. 268: 13128-13136. DOI: 10.1016/s0021-9258(19)38628-4 |
0.148 |
|
| 2022 |
Hughes RE, Elliott RJR, Li X, Munro AF, Makda A, Carter RN, Morton NM, Fujihara K, Clemons NJ, Fitzgerald R, O'Neill JR, Hupp T, Carragher NO. Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes. Acs Chemical Biology. PMID 35696676 DOI: 10.1021/acschembio.2c00301 |
0.143 |
|
| 2021 |
Chmielewska AM, Gómez-Herranz M, Gach P, Nekulova M, Tyrakowska M, Lipińska AD, Rychłowski M, Hoffmann W, Król E, Vojtesek B, Sloan RD, Bieńkowska-Szewczyk K, Hupp T, Ball K. The role of IFITM proteins in tick-borne encephalitis virus infection. Journal of Virology. JVI0113021. PMID 34613785 DOI: 10.1128/JVI.01130-21 |
0.139 |
|
| 2006 |
Clyde RG, Bown JL, Hupp TR, Zhelev N, Crawford JW. The role of modelling in identifying drug targets for diseases of the cell cycle. Journal of the Royal Society, Interface. 3: 617-27. PMID 16971330 DOI: 10.1098/rsif.2006.0146 |
0.138 |
|
| 2021 |
Kurkowiak M, Arcimowicz Ł, Chruściel E, Urban-Wójciuk Z, Papak I, Keegan L, O'Connell M, Kowalski J, Hupp T, Marek-Trzonkowska N. The effects of RNA editing in cancer tissue at different stages in carcinogenesis. Rna Biology. 1-16. PMID 33593231 DOI: 10.1080/15476286.2021.1877024 |
0.137 |
|
| 2022 |
Clarke DJ, Murray E, Faktor J, Vojtesek B, MacKay CL, Smith PL, Hupp TR. Corrigendum to "Mass spectrometry analysis of the oxidation states of the pro oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond" [Biochimica et Biophysica Acta 1864 (2016) 551-561]. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140806. PMID 35786535 DOI: 10.1016/j.bbapap.2022.140806 |
0.136 |
|
| 1988 |
Hupp TR, Kaguni JM. Suppression of the Escherichia coli dnaA46 mutation by a mutation in trxA, the gene for thioredoxin. Molecular & General Genetics : Mgg. 213: 471-8. PMID 3054487 DOI: 10.1007/Bf00339618 |
0.136 |
|
| 2020 |
Uhrik L, Hernychova L, Muller P, Kalathiya U, Lisowska MM, Kocikowski M, Parys M, Faktor J, Nekulova M, Nortcliffe C, Zatloukalova P, Ruetgen B, Fahraeus R, Ball KL, Argyle DJ, ... ... Hupp T, et al. Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody. The Biochemical Journal. PMID 33284343 DOI: 10.1042/BCJ20200674 |
0.126 |
|
| 2020 |
Hughes RE, Elliott RJR, Munro AF, Makda A, O'Neill JR, Hupp T, Carragher NO. High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220917115. PMID 32441181 DOI: 10.1177/2472555220917115 |
0.119 |
|
| 2022 |
Piekarska K, Urban-Wójciuk Z, Kurkowiak M, Pelikant-Małecka I, Schumacher A, Sakowska J, Spodnik JH, Arcimowicz Ł, Zielińska H, Tymoniuk B, Renkielska A, Siebert J, Słomińska E, Trzonkowski P, Hupp T, et al. Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity. Nature Communications. 13: 856. PMID 35165293 DOI: 10.1038/s41467-022-28338-0 |
0.114 |
|
| 2023 |
Kurkowiak M, Fletcher S, Daniels A, Mozolewski P, Silvestris DA, Król E, Marek-Trzonkowska N, Hupp T, Tait-Burkard C. Differential RNA editing landscapes in host cell versus the SARS-CoV-2 genome. Iscience. 26: 108031. PMID 37876814 DOI: 10.1016/j.isci.2023.108031 |
0.112 |
|
| 2019 |
Urban-Wojciuk Z, Khan MM, Oyler BL, Fåhraeus R, Marek-Trzonkowska N, Nita-Lazar A, Hupp TR, Goodlett DR. The Role of TLRs in Anti-cancer Immunity and Tumor Rejection. Frontiers in Immunology. 10: 2388. PMID 31695691 DOI: 10.3389/Fimmu.2019.02388 |
0.106 |
|
| 2017 |
McWhinnie FS, Sepp K, Wilson C, Kunath T, Hupp TR, Baker TS, Houston DR, Hulme AN. Mix and Match: Mono-substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29267987 DOI: 10.1002/Chem.201705983 |
0.099 |
|
| 2022 |
Minoli L, Licenziato L, Kocikowski M, Cino M, Dziubek K, Iussich S, Fanelli A, Morello E, Martano M, Hupp T, Vojtesek B, Parys M, Aresu L. Development of Monoclonal Antibodies Targeting Canine PD-L1 and PD-1 and Their Clinical Relevance in Canine Apocrine Gland Anal Sac Adenocarcinoma. Cancers. 14. PMID 36551672 DOI: 10.3390/cancers14246188 |
0.09 |
|
| 2022 |
Dias C, Nita E, Faktor J, Tynan AC, Hernychova L, Vojtesek B, Nylandsted J, Hupp TR, Kunath T, Ball KL. Erratum: CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity. Iscience. 25: 103921. PMID 35243265 DOI: 10.1016/j.isci.2022.103921 |
0.074 |
|
| 2022 |
Yébenes Mayordomo M, Al Shboul S, Gómez-Herranz M, Azfer A, Meynert A, Salter D, Hayward L, Oniscu A, Patton JT, Hupp T, Arends MJ, Alfaro JA. Gorham-Stout case report: a multi-omic analysis reveals recurrent fusions as new potential drivers of the disease. Bmc Medical Genomics. 15: 128. PMID 35668402 DOI: 10.1186/s12920-022-01277-x |
0.072 |
|
| 2021 |
Ococks E, Sharma S, Tian Ng AW, Aleshin A, Fitzgerald RC, Smyth E, Fitzgerald RC, Edwards PAW, Grehan N, Nutzinger B, Fidziukiewicz E, Redmond AM, Northrop A, Abbas S, ... ... Hupp TR, et al. Serial ctDNA detection using a personalized, tumor-informed assay in esophageal adenocarcinoma patients following resection. Gastroenterology. PMID 34284036 DOI: 10.1053/j.gastro.2021.07.011 |
0.049 |
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