| Year |
Citation |
Score |
| 2022 |
Mantilla G, Peréz-Gordones MC, Cisneros-Montufar S, Benaim G, Navarro JC, Mendoza M, Ramírez-Iglesias JR. Structural Analysis and Diversity of Calmodulin-Binding Domains in Membrane and Intracellular Ca-ATPases. The Journal of Membrane Biology. PMID 36454258 DOI: 10.1007/s00232-022-00275-5 |
0.472 |
|
| 2021 |
Pérez-Gordones MC, Ramírez-Iglesias JR, Benaim G, Mendoza M. A store-operated Ca-entry in Trypanosoma equiperdum: Physiological evidences of its presence. Molecular and Biochemical Parasitology. 244: 111394. PMID 34216677 DOI: 10.1016/j.molbiopara.2021.111394 |
0.579 |
|
| 2020 |
Rey-Cibati A, Valladares-Delgado M, Benaim G. Determination of Intracellular Ca Concentration in the Human Pathogens Trypanosomatids and by the Use of the Fluorescent Ca Indicator Fura-2. Bio-Protocol. 10: e3766. PMID 33659424 DOI: 10.21769/BioProtoc.3766 |
0.626 |
|
| 2020 |
Benaim G, Paniz-Mondolfi AE, Sordillo EM. Rationale for Use of Amiodarone and Its Derivatives for Treatment of Chagas' Disease and Leishmaniasis. Current Pharmaceutical Design. PMID 32988342 DOI: 10.2174/1381612826666200928161403 |
0.408 |
|
| 2020 |
Benaim G, Paniz-Mondolfi AE, Sordillo EM, Martinez-Sotillo N. Disruption of Intracellular Calcium Homeostasis as a Therapeutic Target Against . Frontiers in Cellular and Infection Microbiology. 10: 46. PMID 32133302 DOI: 10.3389/Fcimb.2020.00046 |
0.716 |
|
| 2020 |
Gil Z, Martinez-Sotillo N, Pinto-Martinez A, Mejias F, Martinez JC, Galindo I, Oldfield E, Benaim G. SQ109 inhibits proliferation of Leishmania donovani by disruption of intracellular Ca homeostasis, collapsing the mitochondrial electrochemical potential (ΔΨ) and affecting acidocalcisomes. Parasitology Research. PMID 31897791 DOI: 10.1007/S00436-019-06560-Y |
0.533 |
|
| 2019 |
Rodriguez-Duran J, Pinto-Martinez A, Castillo C, Benaim G. Identification and Electrophysiological Properties of a Sphingosine-dependent Plasma Membrane Ca Channel in Trypanosoma cruzi. The Febs Journal. PMID 31162791 DOI: 10.1111/Febs.14947 |
0.605 |
|
| 2019 |
Martinez-Sotillo N, Pinto-Martínez A, Hejchman E, Benaim G. Antiproliferative effect of a benzofuran derivate based on the structure of amiodarone on Leishmania donovani affecting mitochondria, acidocalcisomes and intracellular Ca homeostasis. Parasitology International. PMID 30794871 DOI: 10.1016/J.Parint.2019.02.006 |
0.645 |
|
| 2018 |
Ramírez-Iglesias JR, Pérez-Gordones MC, Castillo JRD, Mijares A, Benaim G, Mendoza M. Identification and characterization of a calmodulin binding domain in the plasma membrane Ca-ATPase from Trypanosoma equiperdum. Molecular and Biochemical Parasitology. PMID 29752964 DOI: 10.1016/J.Molbiopara.2018.04.005 |
0.46 |
|
| 2018 |
Pinto-Martinez A, Hernández-Rodríguez V, Rodríguez-Durán J, Hejchman E, Benaim G. Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure. Experimental Parasitology. 189: 8-15. PMID 29684665 DOI: 10.1016/J.Exppara.2018.04.010 |
0.652 |
|
| 2018 |
Pinto-Martinez AK, Rodriguez-Durán J, Serrano-Martin X, Hernandez-Rodriguez V, Benaim G. Mechanism of Action of Miltefosine on Leishmania donovani Involves the Impairment of Acidocalcisome Function and the Activation of the Sphingosine-Dependent Plasma Membrane Ca Channel. Antimicrobial Agents and Chemotherapy. 62. PMID 29061745 DOI: 10.1128/Aac.01614-17 |
0.625 |
|
| 2017 |
Pérez-Gordones MC, Ramírez-Iglesias JR, Cervino V, Uzcanga GL, Benaim G, Mendoza M. Evidence of the presence of a calmodulin-sensitive plasma membrane Ca(2+)-ATPase in Trypanosoma equiperdum. Molecular and Biochemical Parasitology. PMID 28213174 DOI: 10.1016/J.Molbiopara.2017.02.001 |
0.561 |
|
| 2016 |
García-García V, Oldfield E, Benaim G. Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109. Antimicrobial Agents and Chemotherapy. PMID 27458218 DOI: 10.1128/Aac.00945-16 |
0.482 |
|
| 2016 |
Benaim G, Pimentel AA, Felibertt P, Mayora A, Colman L, Sojo F, Rojas H, De Sanctis JB. Sphingosine inhibits the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) activity. Biochemical and Biophysical Research Communications. 473: 572-7. PMID 27033604 DOI: 10.1016/J.Bbrc.2016.03.123 |
0.717 |
|
| 2015 |
Figarella K, Marsiccobetre S, Arocha I, Colina W, Hasegawa M, Rodriguez M, Rodriguez-Acosta A, Duszenko M, Benaim G, Uzcategui NL. Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca(2+) release in Leishmania mexicana promastigotes. Microbial Cell (Graz, Austria). 3: 14-28. PMID 28357313 DOI: 10.15698/mic2016.01.471 |
0.354 |
|
| 2015 |
Stateva SR, Salas V, Benguría A, Cossío I, Anguita E, Martín-Nieto J, Benaim G, Villalobo A. The activating role of phospho-(Tyr)-calmodulin on the epidermal growth factor receptor. The Biochemical Journal. 472: 195-204. PMID 26399481 DOI: 10.1042/Bj20150851 |
0.407 |
|
| 2015 |
Stateva SR, Salas V, Anguita E, Benaim G, Villalobo A. Ca2+/Calmodulin and Apo-Calmodulin Both Bind to and Enhance the Tyrosine Kinase Activity of c-Src. Plos One. 10: e0128783. PMID 26058065 DOI: 10.1371/Journal.Pone.0128783 |
0.578 |
|
| 2015 |
Stateva SR, Salas V, Benaim G, Menéndez M, Solís D, Villalobo A. Characterization of phospho-(tyrosine)-mimetic calmodulin mutants. Plos One. 10: e0120798. PMID 25830911 DOI: 10.1371/Journal.Pone.0120798 |
0.396 |
|
| 2015 |
Veiga-Santos P, Li K, Lameira L, de Carvalho TM, Huang G, Galizzi M, Shang N, Li Q, Gonzalez-Pacanowska D, Hernandez-Rodriguez V, Benaim G, Guo RT, Urbina JA, Docampo R, de Souza W, et al. SQ109, a new drug lead for Chagas disease. Antimicrobial Agents and Chemotherapy. 59: 1950-61. PMID 25583723 DOI: 10.1128/Aac.03972-14 |
0.321 |
|
| 2014 |
Benaim G, Casanova P, Hernandez-Rodriguez V, Mujica-Gonzalez S, Parra-Gimenez N, Plaza-Rojas L, Concepcion JL, Liu YL, Oldfield E, Paniz-Mondolfi A, Suarez AI. Dronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacy. Antimicrobial Agents and Chemotherapy. 58: 2295-303. PMID 24492373 DOI: 10.1128/Aac.01240-13 |
0.597 |
|
| 2013 |
Benaim G, García-Marchán Y, Reyes C, Uzcanga G, Figarella K. Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana. Biochemical and Biophysical Research Communications. 430: 1091-6. PMID 23261440 DOI: 10.1016/J.Bbrc.2012.12.033 |
0.613 |
|
| 2013 |
Rojas H, Colina C, Ramos M, Benaim G, Jaffe E, Caputo C, Di Polo R. Sodium-calcium exchanger modulates the L-glutamate Ca(i) (2+) signalling in type-1 cerebellar astrocytes. Advances in Experimental Medicine and Biology. 961: 267-74. PMID 23224886 DOI: 10.1007/978-1-4614-4756-6_22 |
0.797 |
|
| 2012 |
Pimentel AA, Benaim G. [Ca2+ and sphingolipids as modulators for apoptosis and cancer]. Investigacion Clinica. 53: 84-110. PMID 22524111 |
0.586 |
|
| 2012 |
Benaim G, Hernandez-Rodriguez V, Mujica-Gonzalez S, Plaza-Rojas L, Silva ML, Parra-Gimenez N, Garcia-Marchan Y, Paniz-Mondolfi A, Uzcanga G. In vitro anti-Trypanosoma cruzi activity of dronedarone, a novel amiodarone derivative with an improved safety profile. Antimicrobial Agents and Chemotherapy. 56: 3720-5. PMID 22508311 DOI: 10.1128/Aac.00207-12 |
0.456 |
|
| 2012 |
Pimentel AA, Felibertt P, Sojo F, Colman L, Mayora A, Silva ML, Rojas H, Dipolo R, Suarez AI, Compagnone RS, Arvelo F, Galindo-Castro I, De Sanctis JB, Chirino P, Benaim G. The marine sponge toxin agelasine B increases the intracellular Ca(2+) concentration and induces apoptosis in human breast cancer cells (MCF-7). Cancer Chemotherapy and Pharmacology. 69: 71-83. PMID 21603866 DOI: 10.1007/S00280-011-1677-X |
0.667 |
|
| 2009 |
Serrano-Martín X, Payares G, De Lucca M, Martinez JC, Mendoza-León A, Benaim G. Amiodarone and miltefosine act synergistically against Leishmania mexicana and can induce parasitological cure in a murine model of cutaneous leishmaniasis. Antimicrobial Agents and Chemotherapy. 53: 5108-13. PMID 19805563 DOI: 10.1128/Aac.00505-09 |
0.581 |
|
| 2009 |
Garcia-Marchan Y, Sojo F, Rodriguez E, Zerpa N, Malave C, Galindo-Castro I, Salerno M, Benaim G. Trypanosoma cruzi calmodulin: cloning, expression and characterization. Experimental Parasitology. 123: 326-33. PMID 19703447 DOI: 10.1016/J.Exppara.2009.08.010 |
0.498 |
|
| 2009 |
Pérez-Gordones MC, Lugo MR, Winkler M, Cervino V, Benaim G. Diacylglycerol regulates the plasma membrane calcium pump from human erythrocytes by direct interaction. Archives of Biochemistry and Biophysics. 489: 55-61. PMID 19631607 DOI: 10.1016/J.Abb.2009.07.010 |
0.543 |
|
| 2009 |
Serrano-Martín X, García-Marchan Y, Fernandez A, Rodriguez N, Rojas H, Visbal G, Benaim G. Amiodarone destabilizes intracellular Ca2+ homeostasis and biosynthesis of sterols in Leishmania mexicana. Antimicrobial Agents and Chemotherapy. 53: 1403-10. PMID 19164149 DOI: 10.1128/Aac.01215-08 |
0.571 |
|
| 2008 |
Mendoza M, Uzcanga GL, Pacheco R, Rojas H, Carrasquel LM, García-Marchan Y, Serrano-Martín X, Benaím G, Bubis J, Mijares A. Anti-VSG antibodies induce an increase in Trypanosoma evansi intracellular Ca2+ concentration Parasitology. 135: 1303-1315. PMID 18752709 DOI: 10.1017/S0031182008004903 |
0.685 |
|
| 2008 |
Rojas H, Ramos M, Benaim G, Caputo C, DiPolo R. The activity of the Na+/Ca2+ exchanger largely modulates the Ca2+i signal induced by hypo-osmotic stress in rat cerebellar astrocytes. The effect of osmolarity on exchange activity. The Journal of Physiological Sciences : Jps. 58: 277-9. PMID 18638422 DOI: 10.2170/Physiolsci.Rp009208 |
0.828 |
|
| 2007 |
Rojas H, Colina C, Ramos M, Benaim G, Jaffe EH, Caputo C, DiPolo R. Na+ entry via glutamate transporter activates the reverse Na+/Ca2+ exchange and triggers Ca(i)2+-induced Ca2+ release in rat cerebellar Type-1 astrocytes. Journal of Neurochemistry. 100: 1188-202. PMID 17316398 DOI: 10.1111/J.1471-4159.2006.04303.X |
0.782 |
|
| 2006 |
Benaim G, Sanders JM, Garcia-Marchán Y, Colina C, Lira R, Caldera AR, Payares G, Sanoja C, Burgos JM, Leon-Rossell A, Concepcion JL, Schijman AG, Levin M, Oldfield E, Urbina JA. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. Journal of Medicinal Chemistry. 49: 892-9. PMID 16451055 DOI: 10.1021/Jm050691F |
0.751 |
|
| 2006 |
Oviedo NJ, Benaim G, Cervino V, Proverbio T, Proverbio F, Marín R. The plasma membrane Ca2+-ATPase protein from red blood cells is not modified in preeclampsia. Biochimica Et Biophysica Acta. 1762: 381-5. PMID 16417994 DOI: 10.1016/J.Bbadis.2005.12.001 |
0.601 |
|
| 2005 |
Colina C, Flores A, Castillo C, Garrido Mdel R, Israel A, DiPolo R, Benaim G. Ceramide-1-P induces Ca2+ mobilization in Jurkat T-cells by elevation of Ins(1,4,5)-P3 and activation of a store-operated calcium channel. Biochemical and Biophysical Research Communications. 336: 54-60. PMID 16122699 DOI: 10.1016/J.Bbrc.2005.08.039 |
0.762 |
|
| 2005 |
Salas V, Sánchez-Torres J, Cusidó-Hita DM, García-Marchan Y, Sojo F, Benaim G, Villalobo A. Characterisation of tyrosine-phosphorylation-defective calmodulin mutants. Protein Expression and Purification. 41: 384-92. PMID 15866726 DOI: 10.1016/J.Pep.2005.01.004 |
0.501 |
|
| 2005 |
Colina C, Flores A, Rojas H, Acosta A, Castillo C, Garrido Mdel R, Israel A, DiPolo R, Benaim G. Ceramide increase cytoplasmic Ca2+ concentration in Jurkat T cells by liberation of calcium from intracellular stores and activation of a store-operated calcium channel. Archives of Biochemistry and Biophysics. 436: 333-45. PMID 15797246 DOI: 10.1016/J.Abb.2005.02.014 |
0.791 |
|
| 2004 |
Mendoza M, Mijares A, Rojas H, Colina C, Cervino V, DiPolo R, Benaim G. Evaluation of the presence of a thapsigargin-sensitive calcium store in trypanosomatids using Trypanosoma evansi as a model. The Journal of Parasitology. 90: 1181-3. PMID 15562626 DOI: 10.1645/Ge-263R |
0.846 |
|
| 2002 |
Colina C, Cervino V, Benaim G. Ceramide and sphingosine have an antagonistic effect on the plasma-membrane Ca2+-ATPase from human erythrocytes. The Biochemical Journal. 362: 247-51. PMID 11829762 DOI: 10.1042/0264-6021:3620247 |
0.802 |
|
| 1998 |
Benaim G, Cervino V, Villalobo A. Comparative phosphorylation of calmodulin from trypanosomatids and bovine brain by calmodulin-binding protein kinases. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 120: 57-65. PMID 9827017 DOI: 10.1016/S0742-8413(98)00006-1 |
0.324 |
|
| 1997 |
Bermúdez R, Dagger F, D'Aquino JA, Benaim G, Dawidowicz K. Characterization of mitochondrial electron-transfer in Leishmania mexicana. Molecular and Biochemical Parasitology. 90: 43-54. PMID 9497031 DOI: 10.1016/S0166-6851(97)00131-X |
0.355 |
|
| 1996 |
Suju M, Davila M, Poleo G, Docampo R, Benaim G. Phosphatidylethanol stimulates the plasma-membrane calcium pump from human erythrocytes Biochemical Journal. 317: 933-938. PMID 8760385 DOI: 10.1042/Bj3170933 |
0.591 |
|
| 1996 |
Felibertt P, Bermúdez R, Cervino V, Dawidowicz K, Dagger F, Proverbio T, Marín R, Benaim G. Ouabain-sensitive Na+,K(+)-ATPase in the plasma membrane of Leishmania mexicana. Molecular and Biochemical Parasitology. 74: 179-87. PMID 8719159 DOI: 10.1016/0166-6851(95)02497-2 |
0.341 |
|
| 1995 |
Benaim G, Moreno SN, Hutchinson G, Cervino V, Hermoso T, Romero PJ, Ruiz F, de Souza W, Docampo R. Characterization of the plasma-membrane calcium pump from Trypanosoma cruzi. The Biochemical Journal. 299-303. PMID 7532400 DOI: 10.1042/Bj3060299 |
0.627 |
|
| 1995 |
Benguría A, Martín-Nieto J, Benaim G, Villalobo A. Regulatory interaction between calmodulin and the epidermal growth factor receptor. Annals of the New York Academy of Sciences. 766: 472-476. PMID 7486695 DOI: 10.1111/J.1749-6632.1995.Tb26698.X |
0.392 |
|
| 1994 |
Benaim G, Cervino V, Lopez-Estraño C, Weitzman C. Ethanol stimulates the plasma membrane calcium pump from human erythrocytes. Biochimica Et Biophysica Acta. 1195: 141-8. PMID 7918556 DOI: 10.1016/0005-2736(94)90020-5 |
0.476 |
|
| 1993 |
Docampo R, Gadelha FR, Moreno SN, Benaim G, Hoffmann ME, Vercesi AE. Disruption of Ca2+ homeostasis in Trypanosoma cruzi by crystal violet The Journal of Eukaryotic Microbiology. 40: 311-316. PMID 8508168 DOI: 10.1111/J.1550-7408.1993.Tb04921.X |
0.618 |
|
| 1993 |
Benaim G, Lopez-Estrano C, Docampo R, Moreno SNJ. A calmodulin-stimulated Ca2+ pump in plasma-membrane vesicles from Trypanosoma brucei; Selective inhibition by pentamidine Biochemical Journal. 296: 759-763. PMID 8280074 DOI: 10.1042/Bj2960759 |
0.686 |
|
| 1991 |
Benaim G, Losada S, Gadelha FR, Docampo R. A calmodulin-activated (Ca2+-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi Biochemical Journal. 280: 715-720. PMID 1837215 DOI: 10.1042/Bj2800715 |
0.701 |
|
| 1990 |
Benaim G, Bermudez R, Urbina JA. Ca2+ transport in isolated mitochondrial vesicles from Leishmania braziliensis promastigotes. Molecular and Biochemical Parasitology. 39: 61-8. PMID 2304488 DOI: 10.1016/0166-6851(90)90008-A |
0.376 |
|
| 1990 |
Cohen BE, Benaim G, Ruiz M, Michelangeli F. Increased calcium permeability is not responsible for the rapid lethal effects of amphotericin B on Leishmania sp Febs Letters. 259: 286-288. PMID 2294016 DOI: 10.1016/0014-5793(90)80028-H |
0.68 |
|
| 1990 |
Benaim G, Romero PJ. A calcium pump in plasma membrane vesicles from Leishmania braziliensis. Biochimica Et Biophysica Acta. 1027: 79-84. PMID 2144456 DOI: 10.1016/0005-2736(90)90051-O |
0.702 |
|
| 1990 |
Benaim G, de Meis L. Similarities between the effects of dimethyl sulfoxide and calmodulin on the red blood cell Ca2(+)-ATPase. Biochimica Et Biophysica Acta. 1026: 87-92. PMID 2143083 DOI: 10.1016/0005-2736(90)90336-M |
0.653 |
|
| 1989 |
Benaim G, Meis Ld. Activation of the purified erythrocyte plasma membrane Ca2+- ATPase by organic solvents. Febs Letters. 244: 484-486. PMID 2522061 DOI: 10.1016/0014-5793(89)80589-7 |
0.582 |
|
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