| Year |
Citation |
Score |
| 2022 |
Li F, Kopajtic TA, Katz JL, Luo D, Prisinzano TE, Imler GH, Deschamps JR, Jacobson AE, Rice KC. Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland). 27. PMID 36557961 DOI: 10.3390/molecules27248808 |
0.307 |
|
| 2019 |
Kuskovsky R, Lloyd D, Arora K, Plotkin BJ, Green JM, Boshoff HI, Barry C, Deschamps J, Konaklieva MI. C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity. Bioorganic & Medicinal Chemistry. 115050. PMID 31474471 DOI: 10.1016/J.Bmc.2019.115050 |
0.33 |
|
| 2015 |
Iyer MR, Cinar R, Liu J, Godlewski G, Szanda G, Puhl H, Ikeda SR, Deschamps J, Lee YS, Steinbach PJ, Kunos G. Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists. Molecular Pharmacology. 88: 238-44. PMID 26013543 DOI: 10.1124/Mol.115.098541 |
0.366 |
|
| 2012 |
Iyer MR, Lee YS, Deschamps JR, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity. European Journal of Medicinal Chemistry. 50: 44-54. PMID 22341895 DOI: 10.1016/J.Ejmech.2012.01.025 |
0.314 |
|
| 2011 |
Edwankar RV, Edwankar CR, Deschamps J, Cook JM. Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine. Organic Letters. 13: 5216-9. PMID 21877687 DOI: 10.1021/Ol202101P |
0.357 |
|
| 2011 |
Konaklieva MI, Suwandi LS, Kostova M, Deschamps J. 4,4-Bis(methylthio)azetidin-2-ones as synthons of 1,2- and 1,3-dicarbonyl systems Tetrahedron Letters. 52: 1909-1912. DOI: 10.1016/J.Tetlet.2011.02.046 |
0.315 |
|
| 2009 |
Zhang Y, Lee YS, Rothman RB, Dersch CM, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 39. Enantiomeric n-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans Journal of Medicinal Chemistry. 52: 7570-7579. PMID 19627147 DOI: 10.1021/Jm9004225 |
0.304 |
|
| 2008 |
Zezula J, Singer L, Przybył AK, Hashimoto A, Dersch CM, Rothman RB, Deschamps J, Lee YS, Jacobson AE, Rice KC. Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans. Organic & Biomolecular Chemistry. 6: 2868-83. PMID 18688479 DOI: 10.1039/B803433H |
0.383 |
|
| 2008 |
Smith ED, Ariane Vinson N, Zhong D, Berrang BD, Catanzaro JL, Thomas JB, Navarro HA, Gilmour BP, Deschamps J, Carroll FI. A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay. Bioorganic & Medicinal Chemistry. 16: 822-9. PMID 17976996 DOI: 10.1016/J.Bmc.2007.10.023 |
0.345 |
|
| 2008 |
McElroy T, Thomas JB, Brine GA, Navarro HA, Deschamps J, Carroll FI. A Practical Synthesis of the Kappa Opioid Receptor Selective Agonist (+)-5R,7S,8S-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxospiro[4,5]dec-8-yl]benzeneacetamide (U69,593) Synthesis. 2008: 943-947. DOI: 10.1055/S-2008-1032185 |
0.371 |
|
| 2006 |
Carroll FI, Blough BE, Huang X, Nie Z, Mascarella SW, Deschamps J, Navarro HA. Synthesis and monoamine transporter binding properties of 2,3-cyclo analogues of 3beta-(4'-aminophenyl)-2beta-tropanemethanol. Journal of Medicinal Chemistry. 49: 4589-94. PMID 16854064 DOI: 10.1021/Jm060287W |
0.31 |
|
| 2006 |
Zhang S, Fernandez F, Hazeldine S, Deschamps J, Zhen J, Reith ME, Dutta AK. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters. Journal of Medicinal Chemistry. 49: 4239-47. PMID 16821783 DOI: 10.1021/Jm0601699 |
0.383 |
|
| 2006 |
Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes. Journal of Medicinal Chemistry. 49: 3244-50. PMID 16722642 DOI: 10.1021/Jm060122N |
0.342 |
|
| 2005 |
Carroll FI, Chaudhari S, Thomas JB, Mascarella SW, Gigstad KM, Deschamps J, Navarro HA. N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists. Journal of Medicinal Chemistry. 48: 8182-93. PMID 16366600 DOI: 10.1021/Jm058261C |
0.371 |
|
| 2005 |
Wang YN, Bohle DS, Bonifant CL, Chmurny GN, Collins JR, Davies KM, Deschamps J, Flippen-Anderson JL, Keefer LK, Klose JR, Saavedra JE, Waterhouse DJ, Ivanic J. Chemistry of the diazeniumdiolates: Z ⇌ E isomerism Journal of the American Chemical Society. 127: 5388-5395. PMID 15826177 DOI: 10.1021/Ja042258L |
0.304 |
|
| 2005 |
Runyon SP, Burgess JP, Abraham P, Keverline-Frantz KI, Flippen-Anderson J, Deschamps J, Lewin AH, Navarro HA, Boja JW, Kuhar MJ, Carroll FI. Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product. Bioorganic & Medicinal Chemistry. 13: 2439-49. PMID 15755646 DOI: 10.1016/J.Bmc.2005.01.046 |
0.349 |
|
| 2004 |
Kolhatkar R, Cook CD, Ghorai SK, Deschamps J, Beardsley PM, Reith ME, Dutta AK. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters. Journal of Medicinal Chemistry. 47: 5101-13. PMID 15456254 DOI: 10.1021/Jm049796T |
0.366 |
|
| 2004 |
Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/Jo040159K |
0.314 |
|
| 2003 |
Yu J, Wang T, Liu X, Deschamps J, Flippen-Anderson J, Liao X, Cook JM. General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine. The Journal of Organic Chemistry. 68: 7565-81. PMID 14510528 DOI: 10.1021/Jo030006H |
0.331 |
|
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