Paul C. Sternweis - Publications

Affiliations: 
Pharmacology University of Texas Southwestern Medical Center, Dallas, TX, United States 
 1977-1982 University of Virginia, Charlottesville, VA 
Website:
https://profiles.utsouthwestern.edu/profile/17004/paul-sternweis.html

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Dada O, Gutowski S, Brautigam CA, Chen Z, Sternweis PC. Direct Regulation of p190RhoGEF by Activated Rho and Rac GTPases. Journal of Structural Biology. PMID 29196061 DOI: 10.1016/J.Jsb.2017.11.014  0.384
2014 Carter AM, Gutowski S, Sternweis PC. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs). The Journal of Biological Chemistry. 289: 19737-46. PMID 24855647 DOI: 10.1074/Jbc.M114.564930  0.455
2013 Medina F, Carter AM, Dada O, Gutowski S, Hadas J, Chen Z, Sternweis PC. Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins Journal of Biological Chemistry. 288: 11325-11333. PMID 23493395 DOI: 10.1074/Jbc.M113.450056  0.369
2013 Jiang LI, Wang JE, Sternweis PC. Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway. Molecular Pharmacology. 83: 587-93. PMID 23229509 DOI: 10.1124/Mol.112.082446  0.368
2013 Jiang LI, Sternweis PC, Wang JE. Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation. Molecular Immunology. 54: 14-22. PMID 23178822 DOI: 10.1016/J.Molimm.2012.10.027  0.307
2012 Chen Z, Guo L, Hadas J, Gutowski S, Sprang SR, Sternweis PC. Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain. The Journal of Biological Chemistry. 287: 25490-500. PMID 22661716 DOI: 10.1074/Jbc.M111.333716  0.405
2011 Chen Z, Guo L, Sprang SR, Sternweis PC. Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF. Protein Science : a Publication of the Protein Society. 20: 107-17. PMID 21064165 DOI: 10.1002/Pro.542  0.354
2010 Chen Z, Medina F, Liu MY, Thomas C, Sprang SR, Sternweis PC. Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation. The Journal of Biological Chemistry. 285: 21070-81. PMID 20430886 DOI: 10.1074/Jbc.M110.122549  0.315
2010 Callender HL, Horn MA, DeCamp DL, Sternweis PC, Alex Brown H. Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage Journal of Theoretical Biology. 262: 679-690. PMID 19883664 DOI: 10.1016/J.Jtbi.2009.10.030  0.321
2009 Wall EA, Zavzavadjian JR, Chang MS, Randhawa B, Zhu X, Hsueh RC, Liu J, Driver A, Bao XR, Sternweis PC, Simon MI, Fraser ID. Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105. Science Signaling. 2: ra28. PMID 19531803 DOI: 10.1126/Scisignal.2000202  0.337
2008 Chen Z, Singer WD, Danesh SM, Sternweis PC, Sprang SR. Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF. Structure (London, England : 1993). 16: 1532-43. PMID 18940608 DOI: 10.1016/J.Str.2008.07.009  0.393
2008 Jiang LI, Collins J, Davis R, Fraser ID, Sternweis PC. Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII. The Journal of Biological Chemistry. 283: 23429-39. PMID 18541530 DOI: 10.1074/Jbc.M803281200  0.418
2007 Sternweis PC, Carter AM, Chen Z, Danesh SM, Hsiung YF, Singer WD. Regulation of Rho guanine nucleotide exchange factors by G proteins. Advances in Protein Chemistry. 74: 189-228. PMID 17854659 DOI: 10.1016/S0065-3233(07)74006-8  0.433
2007 Jiang LI, Collins J, Davis R, Lin KM, DeCamp D, Roach T, Hsueh R, Rebres RA, Ross EM, Taussig R, Fraser I, Sternweis PC. Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway. The Journal of Biological Chemistry. 282: 10576-84. PMID 17283075 DOI: 10.1074/Jbc.M609695200  0.592
2006 Natarajan M, Lin KM, Hsueh RC, Sternweis PC, Ranganathan R. A global analysis of cross-talk in a mammalian cellular signalling network. Nature Cell Biology. 8: 571-80. PMID 16699502 DOI: 10.1038/Ncb1418  0.308
2005 Chen Z, Singer WD, Sternweis PC, Sprang SR. Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator. Nature Structural & Molecular Biology. 12: 191-7. PMID 15665872 DOI: 10.1038/Nsmb888  0.394
2004 Wang Q, Liu M, Kozasa T, Rothestein JD, Sternweis PC, Neubig RR. Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins. Methods in Enzymology. 389: 244-65. PMID 15313570 DOI: 10.1016/S0076-6879(04)89015-3  0.317
2004 Wang Q, Liu M, Kozasa T, Rothstein JD, Sternweis PC, Neubig RR. Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells. The Journal of Biological Chemistry. 279: 28831-4. PMID 15143072 DOI: 10.1074/Jbc.C400105200  0.387
2004 Gallagher ED, Gutowski S, Sternweis PC, Cobb MH. RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity. The Journal of Biological Chemistry. 279: 1872-7. PMID 14581471 DOI: 10.1074/Jbc.M309525200  0.344
2003 Chen Z, Singer WD, Wells CD, Sprang SR, Sternweis PC. Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF. The Journal of Biological Chemistry. 278: 9912-9. PMID 12525488 DOI: 10.1074/Jbc.M212695200  0.353
2002 Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, ... ... Sternweis PC, et al. Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6. PMID 12478301 DOI: 10.1038/Nature01304  0.615
2002 Christerson LB, Gallagher E, Vanderbilt CA, Whitehurst AW, Wells C, Kazempour R, Sternweis PC, Cobb MH. p115 Rho GTPase activating protein interacts with MEKK1. Journal of Cellular Physiology. 192: 200-8. PMID 12115726 DOI: 10.1002/Jcp.10125  0.365
2002 Wells CD, Liu MY, Jackson M, Gutowski S, Sternweis PM, Rothstein JD, Kozasa T, Sternweis PC. Mechanisms for reversible regulation between G13 and Rho exchange factors. The Journal of Biological Chemistry. 277: 1174-81. PMID 11698392 DOI: 10.1074/Jbc.M105274200  0.478
2002 Wells C, Jiang X, Gutowski S, Sternweis PC. Functional characterization of p115 RhoGEF. Methods in Enzymology. 345: 371-82. PMID 11665621 DOI: 10.1016/S0076-6879(02)45030-6  0.472
2002 Jiang X, Gutowski S, Singer WD, Sternweis PC. Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D. Methods in Enzymology. 345: 328-34. PMID 11665616 DOI: 10.1016/S0076-6879(02)45026-4  0.398
2001 Chen Z, Wells CD, Sternweis PC, Sprang SR. Structure of the rgRGS domain of p115RhoGEF. Nature Structural Biology. 8: 805-9. PMID 11524686 DOI: 10.1038/Nsb0901-805  0.412
2001 Wells CD, Gutowski S, Bollag G, Sternweis PC. Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor. The Journal of Biological Chemistry. 276: 28897-905. PMID 11384980 DOI: 10.1074/Jbc.M102913200  0.42
2001 Liu M, Gutowski S, Sternweis PC. The C Terminus of Mammalian Phospholipase D Is Required for Catalytic Activity Journal of Biological Chemistry. 276: 5556-5562. DOI: 10.1074/Jbc.M006404200  0.351
1999 Faulkner A, Chen X, Rush J, Horazdovsky B, Waechter CJ, Carman GM, Sternweis PC. The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae Journal of Biological Chemistry. 274: 14831-14837. PMID 10329682 DOI: 10.1074/Jbc.274.21.14831  0.303
1998 Xie Z, Fang M, Rivas MP, Faulkner AJ, Sternweis PC, Engebrecht JA, Bankaitis VA. Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proceedings of the National Academy of Sciences of the United States of America. 95: 12346-51. PMID 9770489 DOI: 10.1073/Pnas.95.21.12346  0.357
1998 Hart MJ, Jiang X, Kozasa T, Roscoe W, Singer WD, Gilman AG, Sternweis PC, Bollag G. Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science (New York, N.Y.). 280: 2112-4. PMID 9641916 DOI: 10.1126/Science.280.5372.2112  0.662
1998 Kozasa T, Jiang X, Hart MJ, Sternweis PM, Singer WD, Gilman AG, Bollag G, Sternweis PC. p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13. Science (New York, N.Y.). 280: 2109-11. PMID 9641915 DOI: 10.1126/Science.280.5372.2109  0.652
1997 Roth MG, Sternweis PC. The role of lipid signaling in constitutive membrane traffic. Current Opinion in Cell Biology. 9: 519-26. PMID 9261058 DOI: 10.1016/S0955-0674(97)80028-2  0.384
1997 Singer WD, Brown HA, Sternweis PC. Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D. Annual Review of Biochemistry. 66: 475-509. PMID 9242915 DOI: 10.1146/Annurev.Biochem.66.1.475  0.403
1997 Taylor P, Ross EM, Sternweis PC, Neubig RR, McCammon JA. Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997). Molecular Pharmacology. 52: 1-5. PMID 9224805 DOI: 10.1124/Mol.52.1.1  0.484
1997 Wilk-Blaszczak MA, Singer WD, Quill T, Miller B, Frost JA, Sternweis PC, Belardetti F. The Monomeric G-Proteins Rac1 and/or Cdc42 Are Required for the Inhibition of Voltage-Dependent Calcium Current by Bradykinin The Journal of Neuroscience. 17: 4094-4100. DOI: 10.1523/Jneurosci.17-11-04094.1997  0.408
1996 Ktistakis NT, Brown HA, Waters MG, Sternweis PC, Roth MG. Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles. The Journal of Cell Biology. 134: 295-306. PMID 8707816 DOI: 10.1083/Jcb.134.2.295  0.345
1996 Singer WD, Brown HA, Jiang X, Sternweis PC. Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity. The Journal of Biological Chemistry. 271: 4504-10. PMID 8626805 DOI: 10.1074/Jbc.271.8.4504  0.475
1996 Brown HA, Sternweis PC. Stimulation of phospholipase D by ADP-ribosylation factor. Methods in Enzymology. 257: 313-24. PMID 8583935 DOI: 10.1016/S0076-6879(95)57035-7  0.369
1995 Singer WD, Brown HA, Bokoch GM, Sternweis PC. Resolved phospholipase D activity is modulated by cytosolic factors other than Arf. The Journal of Biological Chemistry. 270: 14944-50. PMID 7797474 DOI: 10.1074/Jbc.270.25.14944  0.634
1995 Brown HA, Gutowski S, Kahn RA, Sternweis PC. Partial purification and characterization of Arf-sensitive phospholipase D from porcine brain Journal of Biological Chemistry. 270: 14935-14943. PMID 7797473 DOI: 10.1074/Jbc.270.25.14935  0.451
1995 Ktistakis NT, Brown HA, Sternweis PC, Roth MG. Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A. Proceedings of the National Academy of Sciences of the United States of America. 92: 4952-6. PMID 7761430 DOI: 10.1073/Pnas.92.11.4952  0.389
1994 Sternweis PC, Smrcka AV. G proteins in signal transduction: the regulation of phospholipase C. Ciba Foundation Symposium. 176: 96-106; discussion 1. PMID 8299429 DOI: 10.1002/9780470514450.ch7  0.592
1994 Wilk-Blaszczak MA, Gutowski S, Sternweis PC, Belardetti F. Bradykinin modulates potassium and calcium currents in neuroblastoma hybrid cells via different pertussis toxin-insensitive pathways. Neuron. 12: 109-16. PMID 8292355 DOI: 10.1016/0896-6273(94)90156-2  0.401
1994 Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell. 77: 83-93. PMID 8156600 DOI: 10.1016/0092-8674(94)90237-2  0.671
1994 Sternweis PC. The active role of beta gamma in signal transduction. Current Opinion in Cell Biology. 6: 198-203. PMID 8024810 DOI: 10.1016/0955-0674(94)90136-8  0.474
1994 Wilk-Blaszczak MA, Singer WD, Gutowski S, Sternweis PC, Belardetti F. The G protein G13 mediates inhibition of voltage-dependent calcium current by bradykinin. Neuron. 13: 1215-24. PMID 7946358 DOI: 10.1016/0896-6273(94)90059-0  0.398
1994 Pang IH, Smrcka AV, Sternweis PC. Synthesis and applications of affinity matrix containing immobilized beta gamma subunits of G proteins. Methods in Enzymology. 237: 164-74. PMID 7934994 DOI: 10.1016/S0076-6879(94)37060-5  0.652
1993 Kozasa T, Hepler JR, Smrcka AV, Simon MI, Rhee SG, Sternweis PC, Gilman AG. Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits. Proceedings of the National Academy of Sciences of the United States of America. 90: 9176-80. PMID 8415674 DOI: 10.1073/Pnas.90.19.9176  0.766
1993 Sternweis PC, Smrcka AV. Regulation of phospholipase C by G proteins. Trends in Biochemical Sciences. 17: 502-6. PMID 1335185 DOI: 10.1016/0968-0004(92)90340-F  0.636
1993 Smrcka A, Sternweis P. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits Journal of Biological Chemistry. 268: 9667-9674. DOI: 10.1016/s0021-9258(18)98401-2  0.326
1993 Smrcka AV, Sternweis PC. Purification of αq/11 from Brain Methods in Neurosciences. 18: 72-82. DOI: 10.1016/B978-0-12-185285-6.50015-4  0.603
1992 Muntz KH, Sternweis PC, Gilman AG, Mumby SM. Influence of γ subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes Molecular Biology of the Cell. 3: 49-61. PMID 1550955 DOI: 10.1091/Mbc.3.1.49  0.617
1992 Sternweis PC, Smrcka AV, Gutowski S. Hormone signalling via G-protein: regulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by Gq. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 336: 35-41; discussion 41. PMID 1351294 DOI: 10.1098/Rstb.1992.0041  0.684
1991 Smrcka AV, Hepler JR, Brown KO, Sternweis PC. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science (New York, N.Y.). 251: 804-7. PMID 1846707 DOI: 10.1126/Science.1846707  0.758
1991 Wange R, Smrcka A, Sternweis P, Exton J. Photoaffinity labeling of two rat liver plasma membrane proteins with [32P]gamma-azidoanilido GTP in response to vasopressin. Immunologic identification as alpha subunits of the Gq class of G proteins Journal of Biological Chemistry. 266: 11409-11412. DOI: 10.1016/s0021-9258(18)98970-2  0.301
1990 Mumby SM, Casey PJ, Gilman AG, Gutowski S, Sternweis PC. G protein gamma subunits contain a 20-carbon isoprenoid. Proceedings of the National Academy of Sciences of the United States of America. 87: 5873-7. PMID 2116011 DOI: 10.1073/Pnas.87.15.5873  0.652
1990 Sternweis PC, Pang IH. The G protein-channel connection. Trends in Neurosciences. 13: 122-6. PMID 1692167 DOI: 10.1016/0166-2236(90)90002-R  0.405
1990 Pang IH, Sternweis PC. Purification of unique alpha subunits of GTP-binding regulatory proteins (G proteins) by affinity chromatography with immobilized beta gamma subunits. Journal of Biological Chemistry. 265: 18707-18712. DOI: 10.1016/s0021-9258(17)44810-1  0.372
1989 Ewald DA, Iok-Hou P, Sternweis PC, Miller RJ. Differential G protein—mediated coupling of neurotransmitter receptors to Ca2+ channels in rat dorsal root ganglion neurons in vitro Neuron. 2: 1185-1193. PMID 2560387 DOI: 10.1016/0896-6273(89)90185-2  0.309
1989 Pang IH, Sternweis PC. Isolation of the alpha subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits. Proceedings of the National Academy of Sciences of the United States of America. 86: 7814-8. PMID 2510152 DOI: 10.1073/Pnas.86.20.7814  0.435
1983 Northup JK, Smigel MD, Sternweis PC, Gilman AG. The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit. Journal of Biological Chemistry. 258: 11369-11376. DOI: 10.1016/s0021-9258(17)44427-9  0.651
1983 Northup JK, Sternweis PC, Gilman AG. The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit. Journal of Biological Chemistry. 258: 11361-11368. DOI: 10.1016/s0021-9258(17)44426-7  0.652
1982 Sternweis PC, Gilman AG. Aluminum: A requirement for activation of the regulatory component of adenylate cyclase by fluoride Proceedings of the National Academy of Sciences of the United States of America. 79: 4888-4891. PMID 6289322 DOI: 10.1073/Pnas.79.16.4888  0.574
1982 Schleifer LS, Kahn RA, Hanski E, Northup JK, Sternweis PC, Gilman AG. Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase Journal of Biological Chemistry. 257: 20-23. PMID 6273425  0.757
1982 Smith JB, Sternweis PC. Subunit specific antisera to the Escherichia coli ATP synthase: effects on ATPase activity, energy transduction, and enzyme assembly. Archives of Biochemistry and Biophysics. 217: 376-87. PMID 6181743 DOI: 10.1016/0003-9861(82)90514-8  0.38
1981 Gilman AG, Sternweis PC, Northup JK. Purification and properties of the regulatory component of adenylate cyclase Biochemical Society Transactions. 9: 58P. DOI: 10.1042/Bst009058P  0.695
1981 Sternweis P, Northup J, Smigel M, Gilman A. The regulatory component of adenylate cyclase. Purification and properties. Journal of Biological Chemistry. 256: 11517-11526. DOI: 10.1016/s0021-9258(19)68431-0  0.604
1981 Hanski E, Sternweis P, Northup J, Dromerick A, Gilman A. The regulatory component of adenylate cyclase. Purification and properties of the turkey erythrocyte protein. Journal of Biological Chemistry. 256: 12911-12919. DOI: 10.1016/s0021-9258(18)42983-3  0.739
1980 Northup JK, Sternweis PC, Smigel MD, Schleifer LS, Ross EM, Gilman AG. Purification of the regulatory component of adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. 77: 6516-20. PMID 6935665 DOI: 10.1073/Pnas.77.11.6516  0.755
1980 Sternweis PC, Smith JB. Characterization of the inhibitory (epsilon) subunit of the proton-translocating adenosine triphosphatase from Escherichia coli. Biochemistry. 19: 526-31. PMID 6444514 DOI: 10.1021/Bi00544A021  0.404
1977 Sternweis PC, Smith JB. Characterization of the purified membrane attachment (beta) subunit of the proton translocating adenosine triphosphatase from Escherichia coli. Biochemistry. 16: 4020-5. PMID 143953 DOI: 10.1021/Bi00637A013  0.368
1977 Smith JB, Sternweis PC. Purification of membrane attachment and inhibitory subunits of the proton translocating adenosine triphosphatase from Escherichia coli. Biochemistry. 16: 306-11. PMID 138433 DOI: 10.1021/Bi00621A023  0.44
1976 Smith JB, Sternweis PC, Larson RJ, Heppel LA. Subunits of the bacterial proton pump ATPase: a synopsis Journal of Cellular Physiology. 89: 567-568. PMID 137905 DOI: 10.1002/Jcp.1040890412  0.582
1975 Smith JB, Sternweis PC. Restoration of coupling factor activity to Escherichia coli ATPase missing the delta subunit. Biochemical and Biophysical Research Communications. 62: 764-71. PMID 235262 DOI: 10.1016/0006-291X(75)90465-9  0.399
1975 Smith JB, Sternweis PC, Heppel LA. Partial purification of active delta and epsilon subunits of the membrane ATPase from Escherichia coli Journal of Supramolecular and Cellular Biochemistry. 3: 248-255. PMID 127087 DOI: 10.1002/Jss.400030307  0.662
1974 Futai M, Sternweis PC, Heppel LA. Purification and properties of reconstitutively active and inactive adenosinetriphosphatase from Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 71: 2725-2729. PMID 4153028 DOI: 10.1073/Pnas.71.7.2725  0.649
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