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Andrew Buller - Publications

Affiliations: 
2017- Chemistry University of Wisconsin, Madison, Madison, WI 
Area:
Protein engineering, biocatalysis, enzymology, chemical biology
Website:
https://www.chem.wisc.edu/users/abuller
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zmich A, Perkins LJ, Bingman C, Acheson JF, Buller AR. Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family. Acs Catalysis. 13: 11644-11655. PMID 37720819 DOI: 10.1021/acscatal.3c02498  0.416
2022 Meza A, Campbell ME, Zmich A, Thein SA, Grieger AM, McGill MJ, Willoughby PH, Buller AR. Efficient chemoenzymatic synthesis of α-aryl aldehydes as intermediates in C-C bond forming biocatalytic cascades. Acs Catalysis. 12: 10700-10710. PMID 36420479 DOI: 10.1021/acscatal.2c02369  0.387
2022 McDonald AD, Bruffy SK, Kasat AT, Buller AR. Engineering Enzyme Substrate Scope Complementarity for Promiscuous Cascade Synthesis of 1,2-Amino Alcohols. Angewandte Chemie (International Ed. in English). PMID 36136093 DOI: 10.1002/anie.202212637  0.364
2022 McDonald AD, Higgins PM, Buller AR. Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. Nature Communications. 13: 5242. PMID 36068220 DOI: 10.1038/s41467-022-32789-w  0.332
2022 Ellis JM, Campbell ME, Kumar P, Geunes EP, Bingman CA, Buller AR. Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction. Nature Catalysis. 5: 136-143. PMID 35935533 DOI: 10.1038/s41929-022-00743-0  0.447
2022 Smith JL, Madrigal Harrison I, Bingman C, Buller AR. Investigation of β-substitution activity of O-acetylserine sulfhydrolase from Citrullus vulgaris. Chembiochem : a European Journal of Chemical Biology. PMID 35476889 DOI: 10.1002/cbic.202200157  0.45
2021 Watkins-Dulaney EJ, Dunham NP, Straathof S, Turi S, Arnold FH, Buller AR. Asymmetric Alkylation of Ketones Catalyzed by Engineered TrpB. Angewandte Chemie (International Ed. in English). PMID 34269506 DOI: 10.1002/anie.202106938  0.523
2020 Kumar P, Meza A, Ellis JM, Carlson GA, Bingman CA, Buller AR. l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate. Acs Chemical Biology. PMID 33337128 DOI: 10.1021/acschembio.0c00753  0.444
2019 Patel KD, d'Andrea FB, Gaudelli NM, Buller AR, Townsend CA, Gulick AM. Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Nature Communications. 10: 3868. PMID 31455765 DOI: 10.1038/S41467-019-11740-6  0.491
2019 McDonald A, Perkins L, Buller AR. Facile in vitro biocatalytic production of diverse tryptamines. Chembiochem : a European Journal of Chemical Biology. PMID 30864270 DOI: 10.1002/cbic.201900069  0.324
2018 Boville CE, Scheele RA, Koch P, Brinkmann-Chen S, Buller AR, Arnold FH. Engineered biosynthesis of β-alkyl tryptophan analogs. Angewandte Chemie (International Ed. in English). PMID 30215880 DOI: 10.1002/Anie.201807998  0.49
2018 Lewis RD, Garcia-Borràs M, Chalkley MJ, Buller AR, Houk KN, Kan SBJ, Arnold FH. Catalytic iron-carbene intermediate revealed in a cytochrome carbene transferase. Proceedings of the National Academy of Sciences of the United States of America. PMID 29946033 DOI: 10.1073/Pnas.1807027115  0.564
2018 Buller AR, van Roye P, Cahn JKB, Scheele RA, Herger M, Arnold FH. Directed evolution mimics allosteric activation by stepwise tuning of the conformational ensemble. Journal of the American Chemical Society. PMID 29712420 DOI: 10.1021/Jacs.8B03490  0.601
2018 Boville CE, Scheele RA, Koch P, Brinkmann-Chen S, Buller AR, Arnold FH. Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angewandte Chemie. 57: 14764-14768. DOI: 10.2210/Pdb6Cuv/Pdb  0.389
2017 Prier CK, Zhang RK, Buller AR, Brinkmann-Chen S, Arnold FH. Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme. Nature Chemistry. 9: 629-634. PMID 28644476 DOI: 10.1038/Nchem.2783  0.547
2016 Buller AR, van Roye P, Murciano-Calles J, Arnold FH. Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity. Biochemistry. PMID 27935677 DOI: 10.1021/Acs.Biochem.6B01127  0.519
2016 Murciano-Calles J, Romney DK, Brinkmann-Chen S, Buller AR, Arnold FH. A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation. Angewandte Chemie (International Ed. in English). PMID 27510733 DOI: 10.1002/Anie.201606242  0.553
2016 Herger M, van Roye P, Romney DK, Brinkmann-Chen S, Buller AR, Arnold FH. Synthesis of β-branched tryptophan analogs using an engineered subunit of tryptophan synthase. Journal of the American Chemical Society. PMID 27355405 DOI: 10.1021/Jacs.6B04836  0.578
2015 Cahn JK, Brinkmann-Chen S, Buller AR, Arnold FH. Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases. Protein Science : a Publication of the Protein Society. PMID 26644020 DOI: 10.1002/Pro.2852  0.462
2015 Buller AR, Brinkmann-Chen S, Romney DK, Herger M, Murciano-Calles J, Arnold FH. Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26553994 DOI: 10.1073/Pnas.1516401112  0.538
2015 McIntosh JA, Heel T, Buller AR, Chio L, Arnold FH. Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450. Journal of the American Chemical Society. PMID 26299431 DOI: 10.1021/Jacs.5B07107  0.556
2015 Marous DR, Lloyd EP, Buller AR, Moshos KA, Grove TL, Blaszczyk AJ, Booker SJ, Townsend CA. Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 10354-8. PMID 26240322 DOI: 10.1073/Pnas.1508615112  0.633
2015 Cahn JK, Brinkmann-Chen S, Spatzal T, Wiig JA, Buller AR, Einsle O, Hu Y, Ribbe MW, Arnold FH. Cofactor specificity motifs and the induced fit mechanism in Class I ketol-acid reductoisomerases. The Biochemical Journal. PMID 25849365 DOI: 10.1042/Bj20150183  0.513
2014 Hyster TK, Farwell CC, Buller AR, McIntosh JA, Arnold FH. Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination. Journal of the American Chemical Society. 136: 15505-8. PMID 25325618 DOI: 10.1021/Ja509308V  0.698
2014 Buller AR, Freeman MF, Schildbach JF, Townsend CA. Exploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT. Biochemistry. 53: 4273-81. PMID 24933323 DOI: 10.1021/Bi500385D  0.7
2013 Buller AR, Townsend CA. Intrinsic evolutionary constraints on protease structure, enzyme acylation, and the identity of the catalytic triad. Proceedings of the National Academy of Sciences of the United States of America. 110: E653-61. PMID 23382230 DOI: 10.1073/Pnas.1221050110  0.607
2012 Buller AR, Labonte JW, Freeman MF, Wright NT, Schildbach JF, Townsend CA. Autoproteolytic activation of ThnT results in structural reorganization necessary for substrate binding and catalysis. Journal of Molecular Biology. 422: 508-18. PMID 22706025 DOI: 10.1016/J.Jmb.2012.06.012  0.738
2012 Buller AR, Freeman MF, Wright NT, Schildbach JF, Townsend CA. Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 109: 2308-13. PMID 22308359 DOI: 10.1073/Pnas.1113633109  0.683
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