Walter Sandtner - Publications

Affiliations: 
Medical University of Vienna, Austria, Wien, Wien, Austria 
Area:
Neurotransmitter transporter

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Burtscher V, Hotka M, Freissmuth M, Sandtner W. An Electrophysiological Approach to Measure Changes in the Membrane Surface Potential in Real Time. Biophysical Journal. PMID 31409481 DOI: 10.1016/j.bpj.2019.06.033  0.88
2019 Erdem FA, Ilic M, Koppensteiner P, Gołacki J, Lubec G, Freissmuth M, Sandtner W. A comparison of the transport kinetics of glycine transporter 1 and glycine transporter 2. The Journal of General Physiology. PMID 31270129 DOI: 10.1085/jgp.201912318  0.68
2019 Niello M, Cintulova D, Hellsberg E, Jäntsch K, Holy M, Ayatollahi LH, Cozzi NV, Freissmuth M, Sandtner W, Ecker GF, Mihovilovic MD, Sitte HH. para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter. Neuropharmacology. PMID 31028773 DOI: 10.1016/j.neuropharm.2019.04.021  0.68
2019 Burtscher V, Hotka M, Sandtner W. Detection of Ligand-binding to Membrane Proteins by Capacitance Measurements. Bio-Protocol. 9. PMID 30680295 DOI: 10.21769/BioProtoc.3138  0.88
2018 Hasenhuetl PS, Bhat S, Freissmuth M, Sandtner W. Functional selectivity and partial efficacy at the monoamine transporters: a unified model of allosteric modulation and amphetamine-induced substrate release. Molecular Pharmacology. PMID 30567955 DOI: 10.1124/mol.118.114793  0.68
2018 Saha K, Li Y, Holy M, Lehner KR, Bukhari MO, Partilla JS, Sandtner W, Sitte HH, Baumann MH. The synthetic cathinones, butylone and pentylone, are stimulants that act as dopamine transporter blockers but 5-HT transporter substrates. Psychopharmacology. PMID 30345459 DOI: 10.1007/s00213-018-5075-5  0.4
2018 Burtscher V, Hotka M, Li Y, Freissmuth M, Sandtner W. A label-free approach to detect ligand binding to cell surface proteins in real time. Elife. 7. PMID 29697048 DOI: 10.7554/eLife.34944  0.88
2018 Hasenhuetl PS, Bhat S, Mayer FP, Sitte HH, Freissmuth M, Sandtner W. A kinetic account for amphetamine-induced monoamine release. The Journal of General Physiology. PMID 29439119 DOI: 10.1085/jgp.201711915  0.68
2017 Mayer FP, Burchardt NV, Decker AM, Partilla JS, Li Y, McLaughlin G, Kavanagh PV, Sandtner W, Blough BE, Brandt SD, Baumann MH, Sitte HH. Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family. Neuropharmacology. PMID 28988906 DOI: 10.1016/j.neuropharm.2017.10.006  0.4
2017 Bhat S, Hasenhuetl PS, Kasture A, El-Kasaby A, Baumann MH, Blough BE, Sucic S, Sandtner W, Freissmuth M. Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates. The Journal of Biological Chemistry. PMID 28842491 DOI: 10.1074/jbc.M117.794081  0.68
2017 Li Y, Mayer FP, Hasenhuetl PS, Burtscher V, Schicker K, Sitte HH, Freissmuth M, Sandtner W. Occupancy of the zinc-binding site by transition metals decreases the substrate affinity of the human dopamine transporter by an allosteric mechanism. The Journal of Biological Chemistry. 292: 7161. PMID 28455408 DOI: 10.1074/jbc.A116.760140  0.88
2017 Kern C, Erdem FA, El-Kasaby A, Sandtner W, Freissmuth M, Sucic S. The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter. The Journal of Biological Chemistry. 292: 3603-3613. PMID 28104804 DOI: 10.1074/jbc.M116.771360  0.68
2017 Li Y, Mayer FP, Hasenhuetl PS, Burtscher V, Schicker K, Sitte HH, Freissmuth M, Sandtner W. Occupancy of the Zinc Binding-site by Transition Metals decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism. The Journal of Biological Chemistry. PMID 28096460 DOI: 10.1074/jbc.M116.760140  0.88
2016 Sohail A, Jayaraman K, Venkatesan S, Gotfryd K, Daerr M, Gether U, Loland CJ, Wanner KT, Freissmuth M, Sitte HH, Sandtner W, Stockner T. The Environment Shapes the Inner Vestibule of LeuT. Plos Computational Biology. 12: e1005197. PMID 27835643 DOI: 10.1371/journal.pcbi.1005197  0.68
2016 Hasenhuetl PS, Freissmuth M, Sandtner W. Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter. The Journal of Biological Chemistry. 291: 25864-25876. PMID 27756841 DOI: 10.1074/jbc.M116.753319  0.68
2015 Zhu R, Sinwel D, Hasenhuetl PS, Saha K, Kumar V, Zhang P, Rankl C, Holy M, Sucic S, Kudlacek O, Karner A, Sandtner W, Stockner T, Gruber HJ, Freissmuth M, et al. Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites. Angewandte Chemie (International Ed. in English). PMID 26695726 DOI: 10.1002/anie.201508755  0.48
2015 Sandtner W, Stockner T, Hasenhuetl PS, Partilla JS, Seddik A, Zhang Y, Cao J, Holy M, Steinkellner T, Rudnick G, Baumann MH, Ecker GF, Newman AH, Sitte HH. Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters. Molecular Pharmacology. PMID 26519222 DOI: 10.1124/mol.115.101394  0.48
2015 Li Y, Hasenhuetl PS, Schicker K, Sitte HH, Freissmuth M, Sandtner W. Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter. The Journal of Biological Chemistry. 290: 31069-76. PMID 26504078 DOI: 10.1074/jbc.M115.688275  0.68
2015 Venkatesan S, Saha K, Sohail A, Sandtner W, Freissmuth M, Ecker GF, Sitte HH, Stockner T. Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site. Plos Computational Biology. 11: e1004551. PMID 26485255 DOI: 10.1371/journal.pcbi.1004551  0.68
2015 Hasenhuetl PS, Schicker K, Koenig X, Li Y, Sarker S, Stockner T, Sucic S, Sitte HH, Freissmuth M, Sandtner W. Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction. Molecular Pharmacology. 88: 12-8. PMID 25873594 DOI: 10.1124/mol.115.099036  0.68
2015 Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH. 'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1321-31. PMID 25502630 DOI: 10.1038/npp.2014.325  0.32
2014 Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E. A repulsion mechanism explains magnesium permeation and selectivity in CorA. Proceedings of the National Academy of Sciences of the United States of America. 111: 3002-7. PMID 24516146 DOI: 10.1073/pnas.1319054111  0.48
2014 Felts B, Pramod AB, Sandtner W, Burbach N, Bulling S, Sitte HH, Henry LK. The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport. The Journal of Biological Chemistry. 289: 1825-40. PMID 24293367 DOI: 10.1074/jbc.M113.504654  0.48
2014 Baumann MH, Bulling S, Benaderet TS, Saha K, Ayestas MA, Partilla JS, Ali SF, Stockner T, Rothman RB, Sandtner W, Sitte HH. Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1355-65. PMID 24287719 DOI: 10.1038/npp.2013.331  0.48
2014 Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M, Sitte HH. A quantitative model of amphetamine action on the 5-HT transporter. British Journal of Pharmacology. 171: 1007-18. PMID 24251585 DOI: 10.1111/bph.12520  0.48
2014 Koenig X, Kovar M, Boehm S, Sandtner W, Hilber K. Anti-addiction drug ibogaine inhibits hERG channels: a cardiac arrhythmia risk. Addiction Biology. 19: 237-9. PMID 22458604 DOI: 10.1111/j.1369-1600.2012.00447.x  0.48
2013 Villalba-Galea CA, Frezza L, Sandtner W, Bezanilla F. Sensing charges of the Ciona intestinalis voltage-sensing phosphatase. The Journal of General Physiology. 142: 543-55. PMID 24127524 DOI: 10.1085/jgp.201310993  0.48
2012 Hyde HC, Sandtner W, Vargas E, Dagcan AT, Robertson JL, Roux B, Correa AM, Bezanilla F. Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations. Structure (London, England : 1993). 20: 1629-40. PMID 23063010 DOI: 10.1016/j.str.2012.08.022  0.48
2012 Bulling S, Schicker K, Zhang YW, Steinkellner T, Stockner T, Gruber CW, Boehm S, Freissmuth M, Rudnick G, Sitte HH, Sandtner W. The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters. The Journal of Biological Chemistry. 287: 18524-34. PMID 22451652 DOI: 10.1074/jbc.M112.343681  0.48
2012 Schicker K, Uzelac Z, Gesmonde J, Bulling S, Stockner T, Freissmuth M, Boehm S, Rudnick G, Sitte HH, Sandtner W. Unifying concept of serotonin transporter-associated currents. The Journal of Biological Chemistry. 287: 438-45. PMID 22072712 DOI: 10.1074/jbc.M111.304261  0.48
2011 Sandtner W, Egwolf B, Khalili-Araghi F, Sánchez-Rodríguez JE, Roux B, Bezanilla F, Holmgren M. Ouabain binding site in a functioning Na+/K+ ATPase. The Journal of Biological Chemistry. 286: 38177-83. PMID 21911500 DOI: 10.1074/jbc.M111.267682  0.48
2009 Villalba-Galea CA, Sandtner W, Dimitrov D, Mutoh H, Knöpfel T, Bezanilla F. Charge movement of a voltage-sensitive fluorescent protein. Biophysical Journal. 96: L19-21. PMID 19167283 DOI: 10.1016/j.bpj.2008.11.003  0.48
2008 Villalba-Galea CA, Sandtner W, Starace DM, Bezanilla F. S4-based voltage sensors have three major conformations. Proceedings of the National Academy of Sciences of the United States of America. 105: 17600-7. PMID 18818307 DOI: 10.1073/pnas.0807387105  0.48
2007 Sandtner W, Bezanilla F, Correa AM. In vivo measurement of intramolecular distances using genetically encoded reporters. Biophysical Journal. 93: L45-7. PMID 17766346 DOI: 10.1529/biophysj.107.119073  0.48
2005 Hilber B, Scholze P, Dorostkar MM, Sandtner W, Holy M, Boehm S, Singer EA, Sitte HH. Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines. Neuropharmacology. 49: 811-9. PMID 16185723 DOI: 10.1016/j.neuropharm.2005.08.008  0.48
2004 Sandtner W, Szendroedi J, Zarrabi T, Zebedin E, Hilber K, Glaaser I, Fozzard HA, Dudley SC, Todt H. Lidocaine: A foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel Molecular Pharmacology. 66: 648-657. PMID 15322257  0.48
2004 Zebedin E, Sandtner W, Galler S, Szendroedi J, Just H, Todt H, Hilber K. Fiber type conversion alters inactivation of voltage-dependent sodium currents in murine C2C12 skeletal muscle cells American Journal of Physiology - Cell Physiology. 287. PMID 15044148 DOI: 10.1152/ajpcell.00015.2004  0.48
2002 Hilber K, Sandtner W, Kudlacek O, Schreiner B, Glaaser I, Schütz W, Fozzard HA, Dudley SC, Todt H. Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure? Journal of Biological Chemistry. 277: 37105-37115. PMID 12138168 DOI: 10.1074/jbc.M205661200  0.48
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