Lauren M Slosky - Publications

2021- Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
pain, addiction, GPCRs

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Singhal SM, Zell V, Faget L, Slosky LM, Barak LS, Caron MG, Pinkerton AB, Hnasko TS. Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens. Neuropharmacology. 109544. PMID 37055008 DOI: 10.1016/j.neuropharm.2023.109544  0.39
2023 Krumm BE, DiBerto JF, Olsen RHJ, Kang HJ, Slocum ST, Zhang S, Strachan RT, Huang XP, Slosky LM, Pinkerton AB, Barak LS, Caron MG, Kenakin T, Fay JF, Roth BL. Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry. PMID 36917754 DOI: 10.1021/acs.biochem.3c00029  0.441
2022 Slosky LM, Pires A, Bai Y, Clark NB, Hauser ER, Gross JD, Porkka F, Zhou Y, Chen X, Pogorelov VM, Toth K, Wetsel WC, Barak LS, Caron MG. Establishment of multi-stage intravenous self-administration paradigms in mice. Scientific Reports. 12: 21422. PMID 36503898 DOI: 10.1038/s41598-022-24740-2  0.391
2022 Hornburg KJ, Slosky LM, Cofer G, Cook J, Qi Y, Porkka F, Clark NB, Pires A, Petrella JR, White LE, Wetsel WC, Barak L, Caron MG, Johnson GA. Prenatal Heroin Exposure Alters Brain Morphology and Connectivity in Adolescent Mice. Nmr in Biomedicine. e4842. PMID 36259728 DOI: 10.1002/nbm.4842  0.379
2021 Slosky LM, Caron MG, Barak LS. Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery. Trends in Pharmacological Sciences. PMID 33581873 DOI: 10.1016/  0.424
2020 Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, et al. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. PMID 32470395 DOI: 10.1016/J.Cell.2020.04.053  0.41
2019 Toth K, Nagi K, Slosky LM, Rochelle L, Ray C, Kaur S, Shenoy SK, Caron MG, Barak LS. Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246. PMID 32259059 DOI: 10.1021/acsptsci.9b00018  0.379
2019 Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky L, Bai Y, Maloney PR, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TD, Jackson M, Caron MG, Barak LS. Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31390201 DOI: 10.1021/Acs.Jmedchem.9B00340  0.42
2017 Toth K, Slosky LM, Pack TF, Urs NM, Boone P, Mao L, Abraham D, Caron MG, Barak LS. Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.). PMID 28941296 DOI: 10.1002/Syn.22012  0.41
2017 Grenald SA, Doyle TM, Zhang H, Slosky LM, Chen Z, Largent-Milnes TM, Spiegel S, Vanderah TW, Salvemini D. Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. Pain. PMID 28570482 DOI: 10.1097/J.Pain.0000000000000965  0.706
2016 Forte BL, Slosky LM, Zhang H, Arnold M, Staatz WD, Hay M, Largent-Milnes TM, Vanderah TW. Angiotensin-(1-7)/Mas Receptor as an Antinociceptive Agent in Cancer-Induced Bone Pain. Pain. PMID 27541850 DOI: 10.1097/J.Pain.0000000000000690  0.724
2016 Slosky LM, BassiriRad NM, Symons AM, Thompson M, Doyle T, Forte BL, Staatz WD, Bui L, Neumann WL, Mantyh PW, Salvemini D, Largent-Milnes TM, Vanderah TW. The Cystine/Glutamate Antiporter System xc- Drives Breast Tumor Cell Glutamate Release and Cancer-Induced Bone Pain. Pain. PMID 27482630 DOI: 10.1097/J.Pain.0000000000000681  0.705
2015 Slosky LM, Largent-Milnes TM, Vanderah TW. Use of Animal Models in Understanding Cancer-induced Bone Pain. Cancer Growth and Metastasis. 8: 47-62. PMID 26339191 DOI: 10.4137/CGM.S21215  0.698
2015 Slosky LM, Vanderah TW. Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. Expert Opinion On Therapeutic Patents. 25: 443-66. PMID 25576197 DOI: 10.1517/13543776.2014.1000862  0.53
2015 Slosky L, BassiriRad N, Symons-Liguori A, Forte B, Bui L, Largent-Milnes T, Vanderah T. (277) The cystine-glutamate antiporter system xc- drives tumor cell glutamate release and cancer-induced bone pain The Journal of Pain. 16: S45. DOI: 10.1016/J.Jpain.2015.01.195  0.698
2014 Sanchez-Covarrubias L, Slosky LM, Thompson BJ, Zhang Y, Laracuente ML, DeMarco KM, Ronaldson PT, Davis TP. P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac. Plos One. 9: e88516. PMID 24520393 DOI: 10.1371/Journal.Pone.0088516  0.601
2014 Thompson BJ, Sanchez-Covarrubias L, Slosky LM, Zhang Y, Laracuente ML, Ronaldson PT. Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 699-707. PMID 24473481 DOI: 10.1038/Jcbfm.2014.4  0.541
2014 Sanchez-Covarrubias L, Slosky LM, Thompson BJ, Davis TP, Ronaldson PT. Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? Current Pharmaceutical Design. 20: 1422-49. PMID 23789948 DOI: 10.2174/13816128113199990463  0.538
2013 Slosky LM, Thompson BJ, Sanchez-Covarrubias L, Zhang Y, Laracuente ML, Vanderah TW, Ronaldson PT, Davis TP. Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Molecular Pharmacology. 84: 774-86. PMID 24019224 DOI: 10.1124/Mol.113.086298  0.655
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