Year |
Citation |
Score |
2023 |
Dinan JC, McCormick JW, Reynolds KA. Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information. Cold Spring Harbor Perspectives in Biology. PMID 38110247 DOI: 10.1101/cshperspect.a041463 |
0.338 |
|
2020 |
Thompson S, Zhang Y, Ingle C, Reynolds K, Kortemme T. Altered expression of a quality control protease in reshapes the in vivo mutational landscape of a model enzyme. Elife. 9. PMID 32701056 DOI: 10.7554/Elife.53476 |
0.402 |
|
2019 |
McCormick JW, Pincus D, Resnekov O, Reynolds KA. Strategies for Engineering and Rewiring Kinase Regulation. Trends in Biochemical Sciences. PMID 31866305 DOI: 10.1016/J.Tibs.2019.11.005 |
0.334 |
|
2019 |
Tamer YT, Gaszek IK, Abdizadeh H, Batur TA, Reynolds K, Atilgan AR, Atilgan C, Toprak E. High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection. Molecular Biology and Evolution. PMID 30982891 DOI: 10.1093/Molbev/Msz086 |
0.398 |
|
2018 |
Pincus D, Pandey JP, Feder ZA, Creixell P, Resnekov O, Reynolds KA. Engineering allosteric regulation in protein kinases. Science Signaling. 11. PMID 30401787 DOI: 10.1126/Scisignal.Aar3250 |
0.367 |
|
2018 |
Rosensweig C, Reynolds KA, Gao P, Laothamatas I, Shan Y, Ranganathan R, Takahashi JS, Green CB. An evolutionary hotspot defines functional differences between CRYPTOCHROMES. Nature Communications. 9: 1138. PMID 29556064 DOI: 10.1038/S41467-018-03503-6 |
0.563 |
|
2017 |
Narayanan C, Gagné D, Reynolds KA, Doucet N. Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily. Scientific Reports. 7: 3207. PMID 28600532 DOI: 10.1038/S41598-017-03298-4 |
0.34 |
|
2017 |
Pincus D, Resnekov O, Reynolds K. An evolution-based strategy for engineering allosteric regulation. Physical Biology. PMID 28266924 DOI: 10.1088/1478-3975/Aa64A4 |
0.429 |
|
2016 |
Rivoire O, Reynolds KA, Ranganathan R. Evolution-Based Functional Decomposition of Proteins. Plos Computational Biology. 12: e1004817. PMID 27254668 DOI: 10.1371/Journal.Pcbi.1004817 |
0.629 |
|
2015 |
Reynolds KA. A new test of computational protein design: predicting posttranslational modification specificity for the enzyme SMYD2. Structure (London, England : 1993). 23: 11-2. PMID 25565104 DOI: 10.1016/J.Str.2014.12.004 |
0.425 |
|
2013 |
Reynolds KA, Russ WP, Socolich M, Ranganathan R. Evolution-based design of proteins. Methods in Enzymology. 523: 213-35. PMID 23422432 DOI: 10.1016/B978-0-12-394292-0.00010-2 |
0.673 |
|
2011 |
Reynolds KA, McLaughlin RN, Ranganathan R. Hot spots for allosteric regulation on protein surfaces. Cell. 147: 1564-75. PMID 22196731 DOI: 10.1016/J.Cell.2011.10.049 |
0.578 |
|
2011 |
Hanes MS, Reynolds KA, McNamara C, Ghosh P, Bonomo RA, Kirsch JF, Handel TM. Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins. 79: 1267-76. PMID 21294157 DOI: 10.1002/Prot.22961 |
0.696 |
|
2009 |
Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of Molecular Recognition : Jmr. 22: 307-18. PMID 19353579 DOI: 10.1002/Jmr.949 |
0.359 |
|
2009 |
Reynolds KA, Katritch V, Abagyan R. Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators. Journal of Computer-Aided Molecular Design. 23: 273-88. PMID 19148767 DOI: 10.1007/S10822-008-9257-9 |
0.339 |
|
2008 |
Reynolds KA, Hanes MS, Thomson JM, Antczak AJ, Berger JM, Bonomo RA, Kirsch JF, Handel TM. Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface. Journal of Molecular Biology. 382: 1265-75. PMID 18775544 DOI: 10.1016/J.Jmb.2008.05.051 |
0.712 |
|
2007 |
Chowdry AB, Reynolds KA, Hanes MS, Voorhies M, Pokala N, Handel TM. An object-oriented library for computational protein design. Journal of Computational Chemistry. 28: 2378-88. PMID 17471459 DOI: 10.1002/Jcc.20727 |
0.574 |
|
2006 |
Reynolds KA, Thomson JM, Corbett KD, Bethel CR, Berger JM, Kirsch JF, Bonomo RA, Handel TM. Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface. The Journal of Biological Chemistry. 281: 26745-53. PMID 16809340 DOI: 10.1074/Jbc.M603878200 |
0.712 |
|
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