Aviva Tolkovsky - Publications

University of Cambridge, Cambridge, England, United Kingdom 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tolkovsky AM, Spillantini MG. Tau aggregation and its relation to selected forms of neuronal cell death. Essays in Biochemistry. PMID 34897457 DOI: 10.1042/EBC20210030  0.329
2018 Fricker M, Tolkovsky AM, Borutaite V, Coleman M, Brown GC. Neuronal Cell Death. Physiological Reviews. 98: 813-880. PMID 29488822 DOI: 10.1152/physrev.00011.2017  0.353
2016 Brelstaff JH, Tolkovsky A, Spillantini MG. P1-160: Phosphatidylserine Exposure on Cultured Dorsal Root Ganglia Neurons From P301S TAU Mice Suggest Phagoptosis as an Extrinsic Route of Cell Death in Tauopathy Alzheimer's & Dementia. 12: P464-P464. DOI: 10.1016/J.Jalz.2016.06.907  0.353
2013 Fricker M, Vilalta A, Tolkovsky AM, Brown GC. Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia. The Journal of Biological Chemistry. 288: 9145-52. PMID 23386613 DOI: 10.1074/jbc.M112.427880  0.325
2010 Fricker M, O'Prey J, Tolkovsky AM, Ryan KM. Phosphorylation of Puma modulates its apoptotic function by regulating protein stability. Cell Death & Disease. 1: e59. PMID 21364664 DOI: 10.1038/cddis.2010.38  0.314
2010 Fricker M, Papadia S, Hardingham GE, Tolkovsky AM. Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons. Journal of Neurochemistry. 114: 772-83. PMID 20477944 DOI: 10.1111/J.1471-4159.2010.06804.X  0.31
2010 Léveillé F, Papadia S, Fricker M, Bell KF, Soriano FX, Martel MA, Puddifoot C, Habel M, Wyllie DJ, Ikonomidou C, Tolkovsky AM, Hardingham GE. Suppression of the intrinsic apoptosis pathway by synaptic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2623-35. PMID 20164347 DOI: 10.1523/Jneurosci.5115-09.2010  0.332
2009 Ciechomska IA, Goemans GC, Skepper JN, Tolkovsky AM. Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. Oncogene. 28: 2128-41. PMID 19347031 DOI: 10.1038/onc.2009.60  0.31
2008 King MA, Goemans CG, Hafiz F, Prehn JHM, Wyttenbach A, Tolkovsky AM. Cytoplasmic inclusions of Htt exon1 containing an expanded polyglutamine tract suppress execution of apoptosis in sympathetic neurons Journal of Neuroscience. 28: 14401-14415. PMID 19118173 DOI: 10.1523/JNEUROSCI.4751-08.2008  0.324
2008 Kroemer G, Tolkovsky AM, Zakeri Z. Elan vital, élan létal: One life but multiple deaths Cell Death and Differentiation. 15: 1089-1090. PMID 18552859 DOI: 10.1038/Cdd.2008.62  0.347
2008 Ciechomska IA, Goemans CG, Tolkovsky AM. Molecular links between autophagy and apoptosis Methods in Molecular Biology (Clifton, N.J.). 445: 175-193. PMID 18425451  0.316
2008 Johansen LD, Naumanen T, Knudsen A, Westerlund N, Gromova I, Junttila M, Nielsen C, Bøttzauw T, Tolkovsky A, Westermarck J, Coffey ET, Jäättelä M, Kallunki T. IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration. Journal of Cell Science. 121: 854-64. PMID 18303054 DOI: 10.1242/Jcs.013722  0.33
2008 Goemans CG, Boya P, Skirrow CJ, Tolkovsky AM. Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors Cell Death and Differentiation. 15: 545-554. PMID 18174902 DOI: 10.1038/sj.cdd.4402290  0.302
2006 Wyttenbach A, Tolkovsky AM. The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons. Journal of Neurochemistry. 96: 1213-26. PMID 16478523 DOI: 10.1111/j.1471-4159.2005.03676.x  0.375
2005 Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy. 1: 11-22. PMID 16874045 DOI: 10.4161/Auto.1.1.1513  0.341
2005 Wong HK, Fricker M, Wyttenbach A, Villunger A, Michalak EM, Strasser A, Tolkovsky AM. Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite. Molecular and Cellular Biology. 25: 8732-47. PMID 16166651 DOI: 10.1128/MCB.25.19.8732-8747.2005  0.407
2004 Yung HW, Bal-Price AK, Brown GC, Tolkovsky AM. Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53- and Bax-dependent pathways. Journal of Neurochemistry. 89: 812-21. PMID 15140181 DOI: 10.1111/j.1471-4159.2004.02395.x  0.344
2002 Chiarini LB, de Freitas FG, Leal-Ferreira ML, Tolkovsky A, Linden R. Cytoplasmic c-Jun N-terminal immunoreactivity: a hallmark of retinal apoptosis. Cellular and Molecular Neurobiology. 22: 711-26. PMID 12585690 DOI: 10.1023/A:1021857007976  0.386
2002 Yung HW, Xue L, Tolkovsky AM. Apoptosis-specific protein (ASP 45 kDa) is distinct from human Apg5, the homologue of the yeast autophagic gene apg5. Febs Letters. 531: 168-72. PMID 12417306  0.317
2002 Tolkovsky A. Apoptosis in diabetic neuropathy. International Review of Neurobiology. 50: 145-59. PMID 12198809 DOI: 10.1016/S0074-7742(02)50076-3  0.352
2001 Xue L, Fletcher GC, Tolkovsky AM. Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis. Current Biology : Cb. 11: 361-5. PMID 11267874 DOI: 10.1016/S0960-9822(01)00100-2  0.329
2001 Harding TC, Xue L, Bienemann A, Haywood D, Dickens M, Tolkovsky AM, Uney JB. Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons. The Journal of Biological Chemistry. 276: 4531-4. PMID 11121395 DOI: 10.1074/jbc.C000815200  0.427
2000 Fletcher GC, Xue L, Passingham SK, Tolkovsky AM. Death commitment point is advanced by axotomy in sympathetic neurons. The Journal of Cell Biology. 150: 741-54. PMID 10953000 DOI: 10.1083/JCB.150.4.741  0.303
2000 Roberts ML, Virdee K, Sampson CP, Gordon I, Parone P, Tolkovsky AM. The combination of bcl-2 expression and NGF-deprivation facilitates the selective destruction of BAD protein in living sympathetic neurons. Molecular and Cellular Neurosciences. 16: 97-110. PMID 10924254 DOI: 10.1006/mcne.2000.0867  0.334
1999 Xue L, Fletcher GC, Tolkovsky AM. Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Molecular and Cellular Neurosciences. 14: 180-98. PMID 10576889 DOI: 10.1006/mcne.1999.0780  0.399
1999 Maroney AC, Finn JP, Bozyczko-Coyne D, O'Kane TM, Neff NT, Tolkovsky AM, Park DS, Yan CY, Troy CM, Greene LA. CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults. Journal of Neurochemistry. 73: 1901-12. PMID 10537048  0.425
1999 Anderson CNG, Tolkovsky AM. A Role for MAPK/ERK in Sympathetic Neuron Survival: Protection against a p53-Dependent, JNK-Independent Induction of Apoptosis by Cytosine Arabinoside The Journal of Neuroscience. 19: 664-673. DOI: 10.1523/JNEUROSCI.19-02-00664.1999  0.308
1997 Virdee K, Bannister AJ, Hunt SP, Tolkovsky AM. Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones. Journal of Neurochemistry. 69: 550-61. PMID 9231712 DOI: 10.1046/j.1471-4159.1997.69020550.x  0.382
1997 Tolkovsky A. Neurotrophic factors in action--new dogs and new tricks. Trends in Neurosciences. 20: 1-3. PMID 9004409 DOI: 10.1016/S0166-2236(96)30017-9  0.389
1996 Nobes CD, Reppas JB, Markus A, Tolkovsky AM. Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons. Neuroscience. 70: 1067-79. PMID 8848168 DOI: 10.1016/0306-4522(95)00420-3  0.318
1994 Edwards SN, Tolkovsky AM. Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal. The Journal of Cell Biology. 124: 537-46. PMID 8106551 DOI: 10.1083/JCB.124.4.537  0.323
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