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Carl W. Cotman, PhD - Publications

Neurology University of California, Irvine, Irvine, CA 

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Year Citation  Score
2020 Jacobs DM, Thomas RG, Salmon DP, Jin S, Feldman HH, Cotman CW, Baker LD. Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS-Cog-Exec. Alzheimer's & Dementia (New York, N. Y.). 6: e12059. PMID 32995469 DOI: 10.1002/trc2.12059  0.04
2020 Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging Cell. e13118. PMID 32087004 DOI: 10.1111/Acel.13118  1
2019 Butler CW, Keiser AA, Kwapis JL, Berchtold NC, Wall VL, Wood MA, Cotman CW. Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity. Learning & Memory (Cold Spring Harbor, N.Y.). 26: 485-492. PMID 31732709 DOI: 10.1101/Lm.050278.119  1
2019 Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, ... ... Cotman CW, et al. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific Reports. 9: 15936. PMID 31685865 DOI: 10.1038/S41598-019-52324-0  1
2019 Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, ... ... Cotman CW, et al. Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders. Alzheimer Disease and Associated Disorders. PMID 31513029 DOI: 10.1097/Wad.0000000000000339  1
2019 Walhovd KB, Howell GR, Ritchie SJ, Staff RT, Cotman CW. What are the earlier life contributions to reserve and resilience? Neurobiology of Aging. PMID 31307838 DOI: 10.1016/j.neurobiolaging.2019.04.014  0.04
2019 Berchtold NC, Prieto GA, Phelan M, Gillen DL, Baldi P, Bennett DA, Buchman AS, Cotman CW. Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline. Neurobiology of Aging. 78: 142-154. PMID 30927700 DOI: 10.1016/J.Neurobiolaging.2019.02.012  1
2019 Trujillo-Estrada L, Nguyen C, da Cunha C, Cai L, Forner S, Martini AC, Ager RR, Prieto GA, Cotman CW, Baglietto-Vargas D, LaFerla FM. Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models. Aging Cell. e12919. PMID 30809950 DOI: 10.1111/Acel.12919  1
2019 Prieto GA, Smith ED, Tong L, Nguyen M, Cotman CW. Inhibition of LTP-induced translation by IL-1β reduces the level of newly synthesized proteins in hippocampal dendrites. Acs Chemical Neuroscience. PMID 30695637 DOI: 10.1021/Acschemneuro.8B00511  1
2019 Prieto GA, Smith ED, Tong L, Nguyen M, Cotman CW. P2-202: INHIBITION OF ACTIVITY-DEPENDENT PROTEIN SYNTHESIS BY IL-1β IN HIPPOCAMPAL DENDRITES Alzheimer's & Dementia. 15: P654-P654. DOI: 10.1016/J.Jalz.2019.06.2609  0.01
2019 Tong L, Butler CW, Tucker AI, Prieto GA, Cotman CW. P2-179: MODULATION OF HISTONE H3 LYSINE 9 TRIMETHYLATION REGULATES SYNAPTIC PLASTICITY IN HIPPOCAMPAL NEURONS Alzheimer's & Dementia. 15: P645-P645. DOI: 10.1016/J.Jalz.2019.06.2586  0.01
2018 Baglietto-Vargas D, Prieto GA, Limon A, Forner S, Rodriguez-Ortiz CJ, Ikemura K, Ager RR, Medeiros R, Trujillo-Estrada L, Martini AC, Kitazawa M, Davila JC, Cotman CW, Gutierrez A, LaFerla FM. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. e12791. PMID 29877034 DOI: 10.1111/Acel.12791  1
2018 Kumar S, Frost JL, Cotman CW, Head E, Palmour R, Lemere CA, Walter J. Deposition of phosphorylated amyloid-β in brains of aged nonhuman primates and canines. Brain Pathology (Zurich, Switzerland). 28: 427-430. PMID 29740941 DOI: 10.1111/Bpa.12573  1
2018 Tong L, Prieto GA, Cotman CW. IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation. Journal of Neuroinflammation. 15: 127. PMID 29712570 DOI: 10.1186/S12974-018-1158-9  1
2018 Prieto GA, Tong L, Smith ED, Cotman CW. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemical Research. PMID 29619614 DOI: 10.1007/S11064-018-2517-8  1
2017 Prieto GA, Cotman CW. On the road towards the global analysis of human synapses. Neural Regeneration Research. 12: 1586-1589. PMID 29171413 DOI: 10.4103/1673-5374.217321  1
2017 Prieto GA, Cotman CW. Cytokines and cytokine networks target neurons to modulate long-term potentiation. Cytokine & Growth Factor Reviews. PMID 28377062 DOI: 10.1016/J.Cytogfr.2017.03.005  1
2017 Snigdha S, Yassa MA, deRivera C, Milgram NW, Cotman CW. Pattern separation and goal-directed behavior in the aged canine. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 123-131. PMID 28202716 DOI: 10.1101/Lm.043422.116  1
2017 Carlos AJ, Tong L, Prieto GA, Cotman CW. IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking. Journal of Neuroinflammation. 14: 29. PMID 28153028 DOI: 10.1186/S12974-017-0803-Z  1
2017 Baker LD, Cotman C, Morrison RH, Kipperman SA, Katula J, Lawson V, Johnson C, Chmelo E, Nicklas B, Revta C, Feldman HH. [P2-024]: EXERT: A PHASE 3 MULTI-SITE RANDOMIZED CONTROLLED TRIAL OF AEROBIC EXERCISE IN MCI - STUDY DESIGN AND METHODS Alzheimer's & Dementia. 13: P613-P613. DOI: 10.1016/J.Jalz.2017.06.672  0.01
2016 Prieto GA, Trieu BH, Dang CT, Bilousova T, Gylys KH, Berchtold NC, Lynch G, Cotman CW. Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986924 DOI: 10.1523/Jneurosci.2774-16.2016  1
2016 Abbasi A, de Paula Vieira R, Bischof F, Walter M, Movassaghi M, Berchtold NC, Niess AM, Cotman CW, Northoff H. Sex-specific variation in signaling pathways and gene expression patterns in human leukocytes in response to endotoxin and exercise. Journal of Neuroinflammation. 13: 289. PMID 27832807 DOI: 10.1186/S12974-016-0758-5  1
2016 Mastroeni D, Khdour OM, Delvaux E, Nolz J, Olsen G, Berchtold N, Cotman C, Hecht SM, Coleman PD. Nuclear but not mitochondrial-encoded OXPHOS genes are altered in aging, mild cognitive impairment, and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27793643 DOI: 10.1016/J.Jalz.2016.09.003  1
2016 Snigdha S, Prieto GA, Petrosyan A, Loertscher BM, Dieskau AP, Overman LE, Cotman CW. H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3611-22. PMID 27013689 DOI: 10.1523/JNEUROSCI.2693-15.2016  1
2015 Hoffmann K, Sobol NA, Frederiksen KS, Beyer N, Vogel A, Vestergaard K, Brændgaard H, Gottrup H, Lolk A, Wermuth L, Jacobsen S, Laugesen LP, Gergelyffy RG, Høgh P, Bjerregaard E, ... ... Cotman CW, et al. Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial. Journal of Alzheimer's Disease : Jad. PMID 26682695 DOI: 10.3233/JAD-150817  1
2015 Snigdha S, de Rivera C, Milgram NW, Cotman CW. Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine. Neurobiology of Aging. PMID 26481404 DOI: 10.1016/J.Neurobiolaging.2015.09.015  1
2015 Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, LaFerla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-87. PMID 26305968 DOI: 10.1073/Pnas.1514486112  1
2015 Tinklenberg JR, Kraemer HC, Yaffe K, O'Hara R, Ringman JM, Ashford JW, Yesavage JA, Taylor JL. Donepezil treatment in ethnically diverse patients with Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 23: 384-90. PMID 25747405 DOI: 10.1016/J.Jagp.2014.09.007  1
2015 Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, ... ... Cotman C, et al. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. Jama Neurology. 72: 414-22. PMID 25706306 DOI: 10.1001/Jamaneurol.2014.4040  1
2015 Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, Laferla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-E5087. DOI: 10.1073/pnas.1514486112  1
2015 Hoffmann K, Sobol NA, Frederiksen KS, Beyer N, Vestergaard K, Brændgaard H, Gottrup H, Lolk A, Wermuth L, Jacobsen S, Laugesen L, Gergelyffy R, Høgh P, Bjerregaard E, Vogel A, ... ... Cotman C, et al. Moderate to high-intensity physical exercise in patients with Alzheimer’s disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.468  1
2014 Smith ED, Prieto GA, Tong L, Sears-Kraxberger I, Rice JD, Steward O, Cotman CW. Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. The Journal of Biological Chemistry. 289: 20615-29. PMID 24917666 DOI: 10.1074/Jbc.M114.568659  1
2014 Berchtold NC, Sabbagh MN, Beach TG, Kim RC, Cribbs DH, Cotman CW. Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease. Neurobiology of Aging. 35: 1961-72. PMID 24786631 DOI: 10.1016/J.Neurobiolaging.2014.03.031  1
2014 Snigdha S, de Rivera C, Milgram NW, Cotman CW. Exercise enhances memory consolidation in the aging brain. Frontiers in Aging Neuroscience. 6: 3. PMID 24550824 DOI: 10.3389/Fnagi.2014.00003  1
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Cotman C, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  1
2014 Rice RA, Berchtold NC, Cotman CW, Green KN. Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiology of Aging. 35: 1002-11. PMID 24268883 DOI: 10.1016/J.Neurobiolaging.2013.10.090  1
2013 Hoffmann K, Frederiksen KS, Sobol NA, Beyer N, Vogel A, Simonsen AH, Johannsen P, Lolk A, Terkelsen O, Cotman CW, Hasselbalch SG, Waldemar G. Preserving cognition, quality of life, physical health and functional ability in Alzheimer's disease: the effect of physical exercise (ADEX trial): rationale and design. Neuroepidemiology. 41: 198-207. PMID 24135720 DOI: 10.1159/000354632  1
2013 Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003  1
2013 Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, et al. Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. The American Journal of Pathology. 183: 369-81. PMID 23747948 DOI: 10.1016/J.Ajpath.2013.05.005  1
2013 Intlekofer KA, Berchtold NC, Malvaez M, Carlos AJ, McQuown SC, Cunningham MJ, Wood MA, Cotman CW. Exercise and sodium butyrate transform a subthreshold learning event into long-term memory via a brain-derived neurotrophic factor-dependent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2027-34. PMID 23615664 DOI: 10.1038/Npp.2013.104  1
2013 Poon WW, Carlos AJ, Aguilar BL, Berchtold NC, Kawano CK, Zograbyan V, Yaopruke T, Shelanski M, Cotman CW. β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. The Journal of Biological Chemistry. 288: 16937-48. PMID 23599427 DOI: 10.1074/Jbc.M113.463711  1
2013 Snigdha S, Milgram NW, Willis SL, Albert M, Weintraub S, Fortin NJ, Cotman CW. A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap. Neurobiology of Aging. 34: 1891-901. PMID 23434040 DOI: 10.1016/J.Neurobiolaging.2013.01.018  1
2013 Berchtold NC, Coleman PD, Cribbs DH, Rogers J, Gillen DL, Cotman CW. Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease. Neurobiology of Aging. 34: 1653-61. PMID 23273601 DOI: 10.1016/J.Neurobiolaging.2012.11.024  1
2013 Winchester J, Dick MB, Gillen D, Reed B, Miller B, Tinklenberg J, Mungas D, Chui H, Galasko D, Hewett L, Cotman CW. Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year. Archives of Gerontology and Geriatrics. 56: 96-103. PMID 22959822 DOI: 10.1016/J.Archger.2012.06.016  1
2013 Siette J, Westbrook RF, Cotman C, Sidhu K, Zhu W, Sachdev P, Valenzuela MJ. Age-specific effects of voluntary exercise on memory and the older brain. Biological Psychiatry. 73: 435-42. PMID 22795967 DOI: 10.1016/J.Biopsych.2012.05.034  1
2013 Intlekofer KA, Cotman CW. Exercise counteracts declining hippocampal function in aging and Alzheimer's disease. Neurobiology of Disease. 57: 47-55. PMID 22750524 DOI: 10.1016/j.nbd.2012.06.011  1
2013 Gumbinger C, Reuter B, Wiethölter H, Bruder I, Rode S, Drewitz E, Habscheid W, Daffertshofer M, Diehm C, Neumaier S, Kern R, Ringleb PA, Hacke W, Hennerici MG, Ruffion A, ... ... Cotman CW, et al. Contents Vol. 41, 2013 Neuroepidemiology. 41. DOI: 10.1159/000356901  1
2013 Gumbinger C, Reuter B, Wiethölter H, Bruder I, Rode S, Drewitz E, Habscheid W, Daffertshofer M, Diehm C, Neumaier S, Kern R, Ringleb PA, Hacke W, Hennerici MG, Ruffion A, ... ... Cotman CW, et al. 3rd International Congress on Neurology and Epidemiology. Abu Dhabi, UAE, November 21–23, 2013: Abstracts Neuroepidemiology. 41: 223-316. DOI: 10.1159/000356326  1
2013 Gumbinger C, Reuter B, Wiethölter H, Bruder I, Rode S, Drewitz E, Habscheid W, Daffertshofer M, Diehm C, Neumaier S, Kern R, Ringleb PA, Hacke W, Hennerici MG, Ruffion A, ... ... Cotman CW, et al. Acknowledgements to Referees Neuroepidemiology. 35: 212-213. DOI: 10.1159/000321550  1
2013 Nielson KA, Sandman CA, Mulnard RA, Cotman CW. In reply Journal of the American Geriatrics Society. 45: 654-655. DOI: 10.1111/j.1532-5415.1997.tb03109.x  1
2013 Hoffmann K, Frederiksen KS, Sobol NA, Beyer N, Vogel A, Simonsen AH, Johannsen P, Lolk A, Terkelsen O, Cotman CW, Hasselbalch SG, Waldemar G. Rationale, design and preliminary baseline data of the ADEX study: The effect of physical exercise in Alzheimer's disease Journal of the Neurological Sciences. 333. DOI: 10.1016/J.Jns.2013.07.1295  1
2013 Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279  1
2013 Sink K, Chmelo E, Nicklas B, Katula J, Cotman C, Williamson J, Baker L. P2-367: Pilot trial of buddy-assisted exercise in people with mild cognitive impairment Alzheimer's & Dementia. 9: P494-P494. DOI: 10.1016/J.Jalz.2013.05.1016  0.01
2012 Kim HJ, Park JW, Byun JH, Poon WW, Cotman CW, Fowlkes CC, Jeon NL. Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons. Acs Chemical Neuroscience. 3: 433-8. PMID 24358503 DOI: 10.1021/Cn3000026  1
2012 Tong L, Prieto GA, Kramár EA, Smith ED, Cribbs DH, Lynch G, Cotman CW. Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17714-24. PMID 23223292 DOI: 10.1523/Jneurosci.1253-12.2012  1
2012 Sárvári M, Hrabovszky E, Kalló I, Solymosi N, Likó I, Berchtold N, Cotman C, Liposits Z. Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: Rat and human studies identify strikingly similar changes Journal of Neuroinflammation. 9. PMID 23206327 DOI: 10.1186/1742-2094-9-264  1
2012 Segal SK, Cotman CW, Cahill LF. Exercise-induced noradrenergic activation enhances memory consolidation in both normal aging and patients with amnestic mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 32: 1011-8. PMID 22914593 DOI: 10.3233/Jad-2012-121078  1
2012 Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ, Cotman CW. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. Journal of Neuroinflammation. 9: 179. PMID 22824372 DOI: 10.1186/1742-2094-9-179  1
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Cotman CW, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.08
2012 Chapman SB, Cotman CW, Fillit HM, Gallagher M, van Dyck CH. Clinical trials: new opportunities. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 773-80. PMID 22570132 DOI: 10.1093/gerona/gls126  1
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... Cotman CW, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  1
2012 Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Archives of Neurology. 69: 836-41. PMID 22431837 DOI: 10.1001/Archneurol.2012.85  1
2012 Snigdha S, Smith ED, Prieto GA, Cotman CW. Caspase-3 activation as a bifurcation point between plasticity and cell death. Neuroscience Bulletin. 28: 14-24. PMID 22233886 DOI: 10.1007/S12264-012-1057-5  1
2012 Deeny SP, Winchester J, Nichol K, Roth SM, Wu JC, Dick M, Cotman CW. Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in É›4 carriers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 352-6. PMID 22226798 DOI: 10.1016/J.Jalz.2011.04.010  1
2012 Snigdha S, Astarita G, Piomelli D, Cotman CW. Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. Neuroscience. 202: 326-33. PMID 22183056 DOI: 10.1016/j.neuroscience.2011.12.002  1
2012 Jung KM, Astarita G, Yasar S, Vasilevko V, Cribbs DH, Head E, Cotman CW, Piomelli D. An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. Neurobiology of Aging. 33: 1522-32. PMID 21546126 DOI: 10.1016/j.neurobiolaging.2011.03.012  1
2012 Snigdha S, Christie LA, De Rivera C, Araujo JA, Milgram NW, Cotman CW. Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs. Age (Dordrecht, Netherlands). 34: 67-73. PMID 21336566 DOI: 10.1007/S11357-011-9219-3  1
2012 Fahnestock M, Marchese M, Head E, Pop V, Michalski B, Milgram WN, Cotman CW. BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog. Neurobiology of Aging. 33: 546-54. PMID 20447733 DOI: 10.1016/J.Jveb.2009.12.005  1
2012 Pop V, Head E, Berchtold NC, Glabe CG, Studzinski CM, Weidner AM, Murphy MP, Cotman CW. Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines. Neurobiology of Aging. 33: 108-20. PMID 20434811 DOI: 10.1016/J.Neurobiolaging.2010.02.008  1
2012 Cotman CW, Anderson AJ. Retention of Function in the Aged Brain: The Pivotal Role of β-Amyloid Brain and Memory: Modulation and Mediation of Neuroplasticity. DOI: 10.1093/acprof:oso/9780195082944.003.0008  1
2012 Poon W, Carlos A, Aguilar B, Cotman C. P2-079: Neutrophin-trafficking deficits are mediated by impaired ubiquitin recycling in Alzheimer's disease Alzheimer's & Dementia. 8: P291-P291. DOI: 10.1016/J.Jalz.2012.05.783  0.01
2011 Astarita G, Jung KM, Vasilevko V, Dipatrizio NV, Martin SK, Cribbs DH, Head E, Cotman CW, Piomelli D. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. Plos One. 6: e24777. PMID 22046234 DOI: 10.1371/journal.pone.0024777  1
2011 Snigdha S, Berchtold N, Astarita G, Saing T, Piomelli D, Cotman CW. Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain. Plos One. 6: e24652. PMID 21931796 DOI: 10.1371/Journal.Pone.0024652  1
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Cotman CW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  1
2011 Adlard PA, Engesser-Cesar C, Cotman CW. Mild stress facilitates learning and exercise improves retention in aged mice. Experimental Gerontology. 46: 53-9. PMID 20951791 DOI: 10.1016/j.exger.2010.10.001  1
2011 Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. β-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiology of Aging. 32: 821-33. PMID 19540623 DOI: 10.1016/J.Neurobiolaging.2009.05.012  1
2011 Cotman CW, Head E. The canine model of human aging and disease Advances in Alzheimer's Disease. 1: 15-38. DOI: 10.3233/978-1-60750-733-8-15  1
2011 Valenzuela M, Siette J, Westbrook F, Sidhu K, Cotman C, Sachdev P. P4-443: Cell therapy plus voluntary running rescues memory dysfunction in a rodent model of brain ageing Alzheimer's & Dementia. 7: e65-e66. DOI: 10.1016/J.Jalz.2011.09.139  0.01
2011 Poon W, Aguilar B, Feinberg L, Seow J, Tu T, Cedeno A, Carlos A, Cotman C. P4-194: Neural stem cells rescue deficits in Alzheimer's transgenic mice Alzheimer's & Dementia. 7: S771-S772. DOI: 10.1016/J.Jalz.2011.05.2217  0.01
2011 Adlard PA, Engesser-Cesar C, Cotman CW. Corrigendum to 'Mild stress facilitates learning and exercise improves retention in aged mice' [Experimental Gerontology 46/1 (2011) page 53-59] Experimental Gerontology. 46: 841. DOI: 10.1016/j.exger.2011.01.002  1
2011 Cotman CW, Kahle JS, Korotzer AR. Maintenance and Regulation in Brain of Neurotransmission, Trophic Factors, and Immune Responses Comprehensive Physiology. DOI: 10.1002/Cphy.Cp110113  1
2010 Astarita G, Jung KM, Berchtold NC, Nguyen VQ, Gillen DL, Head E, Cotman CW, Piomelli D. Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. Plos One. 5: e12538. PMID 20838618 DOI: 10.1371/Journal.Pone.0012538  1
2010 Pop V, Head E, Hill MA, Gillen D, Berchtold NC, Muggenburg BA, Milgram NW, Murphy MP, Cotman CW. Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9831-9. PMID 20660265 DOI: 10.1523/Jneurosci.6194-09.2010  1
2010 Coskun PE, Wyrembak J, Derbereva O, Melkonian G, Doran E, Lott IT, Head E, Cotman CW, Wallace DC. Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. Journal of Alzheimer's Disease : Jad. 20: S293-310. PMID 20463402 DOI: 10.3233/JAD-2010-100351  1
2010 Vasilevko V, Pop V, Kim HJ, Saing T, Glabe CC, Milton S, Barrett EG, Cotman CW, Cribbs DH, Head E. Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta. Neurobiology of Disease. 39: 301-10. PMID 20451612 DOI: 10.1016/j.nbd.2010.04.014  1
2010 Berchtold NC, Castello N, Cotman CW. Exercise and time-dependent benefits to learning and memory. Neuroscience. 167: 588-97. PMID 20219647 DOI: 10.1016/J.Neuroscience.2010.02.050  1
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Cotman CW, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.2
2010 Balázs R, Bridges RJ, Cotman CW. Glutamate and Glutamate Receptors in Neurological Diseases Excitatory Amino Acid Transmission in Health and Disease. 1-46. DOI: 10.1093/acprof:oso/9780195150025.003.0012  1
2010 Balázs R, Bridges RJ, Cotman CW. Excitatory Amino Acid Transmission and Synaptic Plasticity Excitatory Amino Acid Transmission in Health and Disease. 1-51. DOI: 10.1093/acprof:oso/9780195150025.003.0011  1
2010 Balázs R, Bridges RJ, Cotman CW. Trafficking of Glutamate Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-22. DOI: 10.1093/acprof:oso/9780195150025.003.0010  1
2010 Balázs R, Bridges RJ, Cotman CW. Molecular Organization of Glutamate Receptors in the Postsynaptic Density Excitatory Amino Acid Transmission in Health and Disease. 1-21. DOI: 10.1093/acprof:oso/9780195150025.003.0009  1
2010 Balázs R, Bridges RJ, Cotman CW. Glutamate Transporters Excitatory Amino Acid Transmission in Health and Disease. 1-29. DOI: 10.1093/acprof:oso/9780195150025.003.0008  1
2010 Balázs R, Bridges RJ, Cotman CW. Metabotropic Glutamate Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-64. DOI: 10.1093/acprof:oso/9780195150025.003.0007  1
2010 Balázs R, Bridges RJ, Cotman CW. Delta Glutamate Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-6. DOI: 10.1093/acprof:oso/9780195150025.003.0006  1
2010 Balázs R, Bridges RJ, Cotman CW. Nmda Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-41. DOI: 10.1093/acprof:oso/9780195150025.003.0005  1
2010 Balázs R, Bridges RJ, Cotman CW. Kainate Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-25. DOI: 10.1093/acprof:oso/9780195150025.003.0004  1
2010 Balázs R, Bridges RJ, Cotman CW. Ampa Receptors Excitatory Amino Acid Transmission in Health and Disease. 1-24. DOI: 10.1093/acprof:oso/9780195150025.003.0003  1
2010 Balázs R, Bridges RJ, Cotman CW. Ionotropic Glutamate Receptors: General Characteristics Excitatory Amino Acid Transmission in Health and Disease. 1-23. DOI: 10.1093/acprof:oso/9780195150025.003.0002  1
2010 Balázs R, Bridges RJ, Cotman CW. Overview and Perspective Excitatory Amino Acid Transmission in Health and Disease. 1-16. DOI: 10.1093/acprof:oso/9780195150025.003.0001  1
2010 Balazs R, Bridges RJ, Cotman CW, Cotman CA. Excitatory Amino Acid Transmission in Health and Disease Excitatory Amino Acid Transmission in Health and Disease. 1-380. DOI: 10.1093/acprof:oso/9780195150025.001.0001  1
2010 Christie L, Opii W, Head E, Araujo J, De Rivera C, Milgram N, Cotman C. Effects of acetyl-L-carnitine and Lipoic Acid supplementation on cognition in aged beagles Journal of Veterinary Behavior. 5: 160. DOI: 10.1016/j.jveb.2009.12.006  0.01
2010 Cotman CW. S1-01-03: Exercise and prevention of dementia Alzheimer's & Dementia. 6: S64-S64. DOI: 10.1016/j.jalz.2010.05.184  0.01
2010 Poon WW, Carlos AJ, Cotman CW, Rohn TT. P2-212: Overexpression of Bcl-2 in APP transgenic mice reduces amyloid pathology Alzheimer's & Dementia. 6: S376-S376. DOI: 10.1016/J.Jalz.2010.05.1261  0.01
2010 Soi-Ampornkul R, Tong L, Thangnipon W, Cotman CW, Balazs R. P2-094: The reduction of neurotrophin-3 induced signal transduction by interleukin-1β in cultured cortical neurons: A model of Alzheimer's disease Alzheimer's & Dementia. 6: S340-S341. DOI: 10.1016/j.jalz.2010.05.1140  0.01
2010 Cotman CW, Smith AD, Schallert T, Zigmond MJ. Exercise in Neurodegenerative Disease and Stroke Encyclopedia of Neuroscience. 123-131. DOI: 10.1016/B978-008045046-9.00499-X  1
2009 Acharya MM, Christie LA, Lan ML, Donovan PJ, Cotman CW, Fike JR, Limoli CL. Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 19150-5. PMID 19901336 DOI: 10.1073/Pnas.0909293106  1
2009 Christie LA, Opii WO, Head E, Araujo JA, de Rivera C, Milgram NW, Cotman CW. Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. Experimental Gerontology. 44: 752-9. PMID 19735717 DOI: 10.1016/J.Exger.2009.08.012  1
2009 Head E, Nukala VN, Fenoglio KA, Muggenburg BA, Cotman CW, Sullivan PG. Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging. Experimental Neurology. 220: 171-6. PMID 19703441 DOI: 10.1016/J.Expneurol.2009.08.014  1
2009 Nichol K, Deeny SP, Seif J, Camaclang K, Cotman CW. Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 287-94. PMID 19560099 DOI: 10.1016/J.Jalz.2009.02.006  1
2009 Taylor AM, Berchtold NC, Perreau VM, Tu CH, Li Jeon N, Cotman CW. Axonal mRNA in uninjured and regenerating cortical mammalian axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4697-707. PMID 19369540 DOI: 10.1523/Jneurosci.6130-08.2009  1
2009 Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J. Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine. Neurochemical Research. 34: 755-63. PMID 18846423 DOI: 10.1007/S11064-008-9850-2  1
2009 Astarita G, Head E, Cotman CW, Piomelli D. P3-011: Omega-3 fatty acid deficit in Alzheimer's disease Alzheimer's & Dementia. 5: P343-P343. DOI: 10.1016/j.jalz.2009.04.1188  0.01
2008 Cotman CW, Head E. The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches. Journal of Alzheimer's Disease : Jad. 15: 685-707. PMID 19096165 DOI: 10.3233/Jad-2008-15413  1
2008 Bain LJ, Jedrziewski K, Morrison-Bogorad M, Albert M, Cotman C, Hendrie H, Trojanowski JQ. Healthy brain aging: A meeting report from the Sylvan M. Cohen Annual Retreat of the University of Pennsylvania Institute on Aging Alzheimer's and Dementia. 4: 443-446. PMID 18945646 DOI: 10.1016/J.Jalz.2008.08.006  1
2008 Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR, Cotman CW. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proceedings of the National Academy of Sciences of the United States of America. 105: 15605-10. PMID 18832152 DOI: 10.1073/Pnas.0806883105  1
2008 Christie LA, Saunders RC, Kowalska DM, MacKay WA, Head E, Cotman CW. Rhinal and dorsolateral prefrontal cortex lesions produce selective impairments in object and spatial learning and memory in canines. The Journal of Comparative Neurology. 511: 257-70. PMID 18792072 DOI: 10.1002/cne.21821  1
2008 Nichol KE, Poon WW, Parachikova AI, Cribbs DH, Glabe CG, Cotman CW. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid. Journal of Neuroinflammation. 5: 13. PMID 18400101 DOI: 10.1186/1742-2094-5-13  1
2008 Parachikova A, Nichol KE, Cotman CW. Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition. Neurobiology of Disease. 30: 121-9. PMID 18258444 DOI: 10.1016/J.Nbd.2007.12.008  1
2008 Li X, Liu Z, Luo C, Jia H, Sun L, Hou B, Shen W, Packer L, Cotman CW, Liu J. Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction. Free Radical Biology & Medicine. 44: 1465-74. PMID 18258206 DOI: 10.1016/j.freeradbiomed.2008.01.004  1
2008 Siegenthaler MM, Berchtold NC, Cotman CW, Keirstead HS. Voluntary running attenuates age-related deficits following SCI. Experimental Neurology. 210: 207-16. PMID 18164294 DOI: 10.1016/J.Expneurol.2007.10.019  1
2008 Soiampornkul R, Tong L, Thangnipon W, Balazs R, Cotman CW. Interleukin-1beta interferes with signal transduction induced by neurotrophin-3 in cortical neurons. Brain Research. 1188: 189-97. PMID 18036576 DOI: 10.1016/j.brainres.2007.10.051  1
2008 Shen W, Liu K, Tian C, Yang L, Li X, Ren J, Packer L, Cotman CW, Liu J. R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes. Diabetologia. 51: 165-74. PMID 18026715 DOI: 10.1007/S00125-007-0852-4  1
2008 Tong L, Balazs R, Soiampornkul R, Thangnipon W, Cotman CW. Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction. Neurobiology of Aging. 29: 1380-93. PMID 17467122 DOI: 10.1016/j.neurobiolaging.2007.02.027  1
2008 Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Region specific neuron loss in the aged canine hippocampus is reduced by enrichment. Neurobiology of Aging. 29: 39-50. PMID 17092609 DOI: 10.1016/J.Neurobiolaging.2006.09.018  1
2008 Opii WO, Joshi G, Head E, Milgram NW, Muggenburg BA, Klein JB, Pierce WM, Cotman CW, Butterfield DA. Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease. Neurobiology of Aging. 29: 51-70. PMID 17055614 DOI: 10.1016/J.Neurobiolaging.2006.09.012  1
2008 Nichol KE, Deeny SP, Caiozzo VJ, Cotman CW. Studies of Physical Activity Intervention in Transgenic Models of Alzheimer's Medicine & Science in Sports & Exercise. 40: 70. DOI: 10.1249/01.Mss.0000321390.45626.26  0.01
2008 Deeny SP, Nichol K, Roth S, Hatfield B, Cotman CW. Use of Neuroimaging to Examine Genotype and Exercise Interactions on Cognitive Function Medicine & Science in Sports & Exercise. 40: 69-70. DOI: 10.1249/01.Mss.0000321389.68496.33  0.01
2008 Cotman CW. Keynote - Exercise Regulates Synaptic Plasticity and Delays Age-Related Brain Pathology and Dysfunction Medicine & Science in Sports & Exercise. 40: 69. DOI: 10.1249/01.mss.0000321387.78798.38  0.01
2008 Cotman C. PL6.1 Keynote lecture: Exercise builds brain health: key roles of growth factor cascades and inflammation Parkinsonism & Related Disorders. 14: S9. DOI: 10.1016/S1353-8020(08)70092-0  0.01
2007 Cotman CW, Berchtold NC. Physical activity and the maintenance of cognition: learning from animal models. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 3: S30-7. PMID 19595972 DOI: 10.1016/J.Jalz.2007.01.013  1
2007 Harris J, Lee H, Vahidi B, Tu C, Cribbs D, Cotman C, Jeon NL. Non-plasma bonding of PDMS for inexpensive fabrication of microfluidic devices. Journal of Visualized Experiments : Jove. 410. PMID 18989450 DOI: 10.3791/410  1
2007 Harris J, Lee H, Vahidi B, Tu C, Cribbs D, Jeon NL, Cotman C. Fabrication of a microfluidic device for the compartmentalization of neuron soma and axons. Journal of Visualized Experiments : Jove. 261. PMID 18989432 DOI: 10.3791/261  1
2007 Harris J, Lee H, Tu CT, Cribbs D, Cotman C, Jeon NL. Preparing e18 cortical rat neurons for compartmentalization in a microfluidic device. Journal of Visualized Experiments : Jove. 305. PMID 18989412 DOI: 10.3791/305  1
2007 Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Molecular Neurodegeneration. 2: 18. PMID 17897471 DOI: 10.1186/1750-1326-2-18  1
2007 Beekly DL, Ramos EM, Lee WW, Deitrich WD, Jacka ME, Wu J, Hubbard JL, Koepsell TD, Morris JC, Kukull WA, Reiman EM, Kowall N, Landreth G, Shelanski M, Welsh-Bohmer K, ... ... Cotman C, et al. The National Alzheimer's Coordinating Center (NACC) database: The uniform data set Alzheimer Disease and Associated Disorders. 21: 249-258. PMID 17804958 DOI: 10.1097/Wad.0B013E318142774E  1
2007 Cotman CW, Berchtold NC, Christie LA. Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends in Neurosciences. 30: 464-72. PMID 17765329 DOI: 10.1016/J.Tins.2007.06.011  1
2007 Parachikova A, Cotman CW. Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease. Neurobiology of Disease. 28: 143-53. PMID 17764962 DOI: 10.1016/J.Nbd.2007.07.001  1
2007 Nichol KE, Parachikova AI, Cotman CW. Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse. Behavioural Brain Research. 184: 124-32. PMID 17698211 DOI: 10.1016/J.Bbr.2007.06.027  1
2007 Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function. Neurobiology of Learning and Memory. 88: 249-59. PMID 17587610 DOI: 10.1016/J.Nlm.2007.05.001  1
2007 Engesser-Cesar C, Ichiyama RM, Nefas AL, Hill MA, Edgerton VR, Cotman CW, Anderson AJ. Wheel running following spinal cord injury improves locomotor recovery and stimulates serotonergic fiber growth. The European Journal of Neuroscience. 25: 1931-9. PMID 17439482 DOI: 10.1111/J.1460-9568.2007.05469.X  1
2007 Celsi F, Svedberg M, Unger C, Cotman CW, Carrì MT, Ottersen OP, Nordberg A, Torp R. Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress. Neurobiology of Disease. 26: 342-52. PMID 17344052 DOI: 10.1016/J.Nbd.2006.12.022  1
2007 Christie LA, Su JH, Tu CH, Dick MC, Zhou J, Cotman CW. Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains. Neurobiology of Disease. 26: 165-73. PMID 17292615 DOI: 10.1016/j.nbd.2006.12.017  1
2007 Jia L, Liu Z, Sun L, Miller SS, Ames BN, Cotman CW, Liu J. Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid. Investigative Ophthalmology & Visual Science. 48: 339-48. PMID 17197552 DOI: 10.1167/Iovs.06-0248  1
2007 Engesser-Cesar C, Anderson AJ, Cotman CW. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. 144: 1033-44. PMID 17137724 DOI: 10.1016/J.Neuroscience.2006.10.016  1
2007 Sharman EH, Bondy SC, Sharman KG, Lahiri D, Cotman CW, Perreau VM. Effects of melatonin and age on gene expression in mouse CNS using microarray analysis. Neurochemistry International. 50: 336-44. PMID 17118492 DOI: 10.1016/J.Neuint.2006.09.001  1
2007 Rhee SW, Taylor AM, Cribbs DH, Cotman CW, Jeon NL. External force-assisted cell positioning inside microfluidic devices. Biomedical Microdevices. 9: 15-23. PMID 17091393 DOI: 10.1007/S10544-006-9002-X  1
2007 Perreau VM, Bondy SC, Cotman CW, Sharman KG, Sharman EH. Melatonin treatment in old mice enables a more youthful response to LPS in the brain. Journal of Neuroimmunology. 182: 22-31. PMID 17070935 DOI: 10.1016/J.Jneuroim.2006.09.005  1
2007 Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiology of Aging. 28: 1821-33. PMID 17052803 DOI: 10.1016/J.Neurobiolaging.2006.08.014  1
2007 Cotman C. S1-01-04: What goes wrong with the brain during aging Alzheimer's & Dementia. 3: S165-S165. DOI: 10.1016/j.jalz.2007.04.100  0.01
2007 Cotman CW, Busciglio J. Signaling mechanisms that mediate Aβ induced neuronal dysfunction Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 133-150. DOI: 10.1007/978-0-387-35135-3_8  1
2006 Carrasco J, Adlard P, Cotman C, Quintana A, Penkowa M, Xu F, Van Nostrand WE, Hidalgo J. Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience. 143: 911-22. PMID 17027170 DOI: 10.1016/J.Neuroscience.2006.08.054  1
2006 Chan C, Moore BE, Cotman CW, Okano H, Tavares R, Hovanesian V, Pinar H, Johanson CE, Svendsen CN, Stopa EG. Musashi1 antigen expression in human fetal germinal matrix development. Experimental Neurology. 201: 515-8. PMID 16777095 DOI: 10.1016/J.Expneurol.2006.04.023  1
2006 Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, et al. Neurobiology of exercise. Obesity (Silver Spring, Md.). 14: 345-56. PMID 16648603 DOI: 10.1038/Oby.2006.46  1
2006 Studzinski CM, Christie LA, Araujo JA, Burnham WM, Head E, Cotman CW, Milgram NW. Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia. Neurobiology of Learning and Memory. 86: 197-204. PMID 16616528 DOI: 10.1016/J.Nlm.2006.02.005  1
2006 Head E, Barrett EG, Murphy MP, Das P, Nistor M, Sarsoza F, Glabe CC, Kayed R, Milton S, Vasilevko V, Milgram NW, Agadjanyan MG, Cribbs DH, Cotman CW. Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine. 24: 2824-34. PMID 16460841 DOI: 10.1016/J.Vaccine.2005.12.058  1
2006 Lu PH, Masterman DA, Mulnard R, Cotman C, Miller B, Yaffe K, Reback E, Porter V, Swerdloff R, Cummings JL. Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men. Archives of Neurology. 63: 177-85. PMID 16344336 DOI: 10.1001/Archneur.63.2.Nct50002  0.08
2006 Chubb C, Inagaki Y, Sheu P, Cummings B, Wasserman A, Head E, Cotman C. BioVision: an application for the automated image analysis of histological sections. Neurobiology of Aging. 27: 1462-76. PMID 16271803 DOI: 10.1016/J.Neurobiolaging.2005.08.023  1
2006 Soi-ampornkul R, Tong L, Thangnipon W, Cotman CW, Balazs R. Impairment of neurotrophin-3-induced phosphoryiation of cAMP response element-binding protein caused by interleukin-1ß in cultured cortical neurons Scienceasia. 32: 115-119. DOI: 10.2306/scienceasia1513-1874.2006.32.115  1
2006 Nichol KE, Parachikova A, Caiozzo V, Cotman C. Exercise Alters Immune Response in Hippocampus of Transgenic Alzheimer Mouse Model and Improves Reference Memory Medicine & Science in Sports & Exercise. 38: S309. DOI: 10.1249/00005768-200605001-02206  0.01
2006 Rodriguez-Ortiz CJ, Prieto GA, Cotman CW, Kitazawa M. P1-236: Aβ OLIGOMERS IMPAIR PLASTICITY BY DYSREGULATING MIR-181A IN PRIMARY HIPPOCAMPAL CULTURES Alzheimer's & Dementia. 14: P368-P368. DOI: 10.1016/J.Jalz.2018.06.241  0.01
2006 Buttini M, Chen M, Head E, Cotman C, Games D. O1-01-04: Inflammatory cell infiltrates are commonly associated with brain vasculature and cerebral amyloid angiopathy in Alzheimer's disease Alzheimer's & Dementia. 2: S8-S9. DOI: 10.1016/j.jalz.2006.05.037  0.01
2005 Araujo JA, Studzinski CM, Head E, Cotman CW, Milgram NW. Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging. Age (Dordrecht, Netherlands). 27: 27-37. PMID 23598601 DOI: 10.1007/S11357-005-4001-Z  1
2005 Cotman CW. The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo. Neurochemical Research. 30: 877-81. PMID 16187222 DOI: 10.1007/s11064-005-6960-y  1
2005 Roudebush P, Zicker SC, Cotman CW, Milgram NW, Muggenburg BA, Head E. Nutritional management of brain aging in dogs. Journal of the American Veterinary Medical Association. 227: 722-8. PMID 16178393 DOI: 10.2460/Javma.2005.227.722  1
2005 Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nature Methods. 2: 599-605. PMID 16094385 DOI: 10.1038/Nmeth777  1
2005 Newman J, Rissman RA, Sarsoza F, Kim RC, Dick M, Bennett DA, Cotman CW, Rohn TT, Head E. Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology. Acta Neuropathologica. 110: 135-44. PMID 15986225 DOI: 10.1007/S00401-005-1027-3  1
2005 Berchtold NC, Chinn G, Chou M, Kesslak JP, Cotman CW. Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus. Neuroscience. 133: 853-61. PMID 15896913 DOI: 10.1016/J.Neuroscience.2005.03.026  1
2005 Perreau VM, Adlard PA, Anderson AJ, Cotman CW. Exercise-induced gene expression changes in the rat spinal cord. Gene Expression. 12: 107-21. PMID 15892452 DOI: 10.3727/000000005783992115  1
2005 Adlard PA, Perreau VM, Pop V, Cotman CW. Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4217-21. PMID 15858047 DOI: 10.1523/JNEUROSCI.0496-05.2005  1
2005 Siwak CT, Tapp PD, Head E, Zicker SC, Murphey HL, Muggenburg BA, Ikeda-Douglas CJ, Cotman CW, Milgram NW. Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 461-9. PMID 15795055 DOI: 10.1016/J.Pnpbp.2004.12.011  1
2005 Christie LA, Studzinski CM, Araujo JA, Leung CS, Ikeda-Douglas CJ, Head E, Cotman CW, Milgram NW. A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 361-9. PMID 15795044 DOI: 10.1016/J.Pnpbp.2004.12.002  1
2005 Cotman CW, Poon WW, Rissman RA, Blurton-Jones M. The role of caspase cleavage of tau in Alzheimer disease neuropathology. Journal of Neuropathology and Experimental Neurology. 64: 104-12. PMID 15751224 DOI: 10.1093/Jnen/64.2.104  1
2005 Head E, Moffat K, Das P, Sarsoza F, Poon WW, Landsberg G, Cotman CW, Murphy MP. Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats. Neurobiology of Aging. 26: 749-63. PMID 15708450 DOI: 10.1016/J.Neurobiolaging.2004.06.015  1
2005 Engesser-Cesar C, Anderson AJ, Basso DM, Edgerton VR, Cotman CW. Voluntary wheel running improves recovery from a moderate spinal cord injury. Journal of Neurotrauma. 22: 157-71. PMID 15665610 DOI: 10.1089/Neu.2005.22.157  1
2005 Adlard PA, Perreau VM, Cotman CW. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of Aging. 26: 511-20. PMID 15653179 DOI: 10.1016/j.neurobiolaging.2004.05.006  1
2005 Kelly PT, Cotman CW. Intermolecular disulfide bonds at central nervous system synaptic junctions. Biochemical and Biophysical Research Communications. 73: 858-64. PMID 15625853 DOI: 10.1016/0006-291X(76)90200-X  0.04
2005 Rhee SW, Taylor AM, Tu CH, Cribbs DH, Cotman CW, Jeon NL. Patterned cell culture inside microfluidic devices. Lab On a Chip. 5: 102-7. PMID 15616747 DOI: 10.1039/B403091E  1
2005 Milgram NW, Head E, Zicker SC, Ikeda-Douglas CJ, Murphey H, Muggenburg B, Siwak C, Tapp D, Cotman CW. Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study. Neurobiology of Aging. 26: 77-90. PMID 15585348 DOI: 10.1016/J.Neurobiolaging.2004.02.014  1
2005 Cotman C. Imaging Techniques - A Vision into the Future? Medicine & Science in Sports & Exercise. 37: S415. DOI: 10.1097/00005768-200505001-02139  0.01
2005 Head E, Cotman CW, Zicker SC, Milgram NW. The use of dietary antioxidants and mitochondrial co-factors to promote successful aging Current Topics in Nutraceutical Research. 3: 85-94.  1
2005 Berchtold NC, Cotman CW, Strobel G, Xiao Q, Trakya FK, Pochet R, Lessmann V, Wang D, Holcomb L, Fahnestock M, Duong T, Busciglio J, Zhu S. Alzheimer research forum live discussion: Brain derived neurotrophic factor and Alzheimer's disease - What is the connection? Journal of Alzheimer's Disease. 7: 173-180.  1
2004 Anderson AJ, Robert S, Huang W, Young W, Cotman CW. Activation of complement pathways after contusion-induced spinal cord injury. Journal of Neurotrauma. 21: 1831-46. PMID 15684772 DOI: 10.1089/Neu.2004.21.1831  1
2004 Liu J, Head E, Kuratsune H, Cotman CW, Ames BN. Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Annals of the New York Academy of Sciences. 1033: 117-31. PMID 15591009 DOI: 10.1196/Annals.1320.011  1
2004 Tapp PD, Siwak CT, Gao FQ, Chiou JY, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su MY. Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8205-13. PMID 15385603 DOI: 10.1523/Jneurosci.1339-04.2004  1
2004 Glaser J, Gonzalez R, Perreau VM, Cotman CW, Keirstead HS. Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury. Journal of Neuroscience Research. 77: 701-8. PMID 15352216 DOI: 10.1002/Jnr.20204  1
2004 Tong L, Balazs R, Thornton PL, Cotman CW. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6799-809. PMID 15282285 DOI: 10.1523/JNEUROSCI.5463-03.2004  1
2004 Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/Jci20640  1
2004 Tapp PD, Siwak CT, Head E, Cotman CW, Murphey H, Muggenburg BA, Ikeda-Douglas C, Milgram NW. Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks. Behavioural Brain Research. 153: 199-210. PMID 15219721 DOI: 10.1016/J.Bbr.2003.12.003  1
2004 Johnson JK, Vogt BA, Kim R, Cotman CW, Head E. Isolated executive impairment and associated frontal neuropathology. Dementia and Geriatric Cognitive Disorders. 17: 360-7. PMID 15178954 DOI: 10.1159/000078183  1
2004 Adlard PA, Perreau VM, Engesser-Cesar C, Cotman CW. The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neuroscience Letters. 363: 43-8. PMID 15157993 DOI: 10.1016/j.neulet.2004.03.058  1
2004 Milgram NW, Head E, Zicker SC, Ikeda-Douglas C, Murphey H, Muggenberg BA, Siwak CT, Tapp PD, Lowry SR, Cotman CW. Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs. Experimental Gerontology. 39: 753-65. PMID 15130670 DOI: 10.1016/J.Exger.2004.01.007  1
2004 Adlard PA, Cotman CW. Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression. Neuroscience. 124: 985-92. PMID 15026138 DOI: 10.1016/j.neuroscience.2003.12.039  1
2004 Whitman GT, Cotman CW. Oligodendrocyte degeneration in AD. Neurobiology of Aging. 25: 33-6. PMID 14675727 DOI: 10.1016/j.neurobiolaging.2003.06.001  1
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, et al. Contents Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 387-389. DOI: 10.1159/000078837  1
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, et al. Subject Index Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 384-385. DOI: 10.1159/000078836  1
2004 CHUBB C, INAGAKI Y, COTMAN C, CUMMINGS B, SHEU PC. SEMANTIC BIOLOGICAL IMAGE MANAGEMENT AND ANALYSIS International Journal On Artificial Intelligence Tools. 13: 881-896. DOI: 10.1142/S0218213004001879  0.01
2004 Tong L, Sheng H, Martinez-Coria H, Balazs R, Cotman CW. P3-312 Expression of certain activity-dependent genes, implicated in neuronal plasticity, is impaired in the hippocampus of amyloid precursor protein transgenic mice Neurobiology of Aging. 25: S444. DOI: 10.1016/S0197-4580(04)81462-3  0.01
2004 Soi-Ampornkul R, Tong L, Thangnipon W, Cotman CW, Balazs R. P3-135 Interleukin-1β impairs activity-dependent camp-response element binding protein signaling of neurotrophin-3 in cerebral cortical neurons Neurobiology of Aging. 25: S393. DOI: 10.1016/S0197-4580(04)81287-9  0.01
2004 Tapp D, Siwak CT, Gao FQ, Chiou J, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su M. P3-066 Changes in frontal lobe volume, executive function, and amyloid load in a canine model of aging Neurobiology of Aging. 25: S371. DOI: 10.1016/S0197-4580(04)81218-1  0.01
2004 Kesslak JP, Chuang KR, Berchtold NC, Cotman C. Erratum to “Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats” [Neurosci. Lett. 353 (2003) 95–98] Neuroscience Letters. 369: 85. DOI: 10.1016/J.Neulet.2004.07.005  0.04
2004 Adlard PA, Perreau VM, Cotman CW. Chronic immobilization stress differentially affects the expression of BDNF mRNA and protein in the mouse hippocampus Stress and Health. 20: 175-180. DOI: 10.1002/smi.1022  1
2003 Taylor AM, Rhee SW, Tu CH, Cribbs DH, Cotman CW, Jeon NL. Microfluidic Multicompartment Device for Neuroscience Research. Langmuir : the Acs Journal of Surfaces and Colloids. 19: 1551-1556. PMID 20725530 DOI: 10.1021/la026417v  1
2003 Haier RJ, Alkire MT, White NS, Uncapher MR, Head E, Lott IT, Cotman CW. Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia. Neurology. 61: 1673-9. PMID 14694028 DOI: 10.1212/01.Wnl.0000098935.36984.25  1
2003 Zhao M, Su J, Head E, Cotman CW. Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease. Neurobiology of Disease. 14: 391-403. PMID 14678756 DOI: 10.1016/j.nbd.2003.07.006  1
2003 Yetley E, Tucker KL, Murphy SP, Haines PS, Stallings VA, Harris TB, Forman B, Russell RM, Messina M, Holick M, Ames BN, Rosenkranz HS, Kramer BS, Mayne ST, Mahady GB, ... Cotman CW, et al. National Institutes of Health Conference: Dietary supplement use in the elderly Nutrition. 19: 981-987. PMID 14624949 DOI: 10.1016/S0899-9007(03)00105-9  1
2003 Nippak PM, Chan AD, Campbell Z, Muggenburg B, Head E, Ikeda-Douglas CJ, Murphey H, Cotman CW, Milgram NW. Response latency in Canis familiaris: mental ability or mental strategy? Behavioral Neuroscience. 117: 1066-75. PMID 14570555 DOI: 10.1037/0735-7044.117.5.1066  1
2003 Head E, Lott IT, Hof PR, Bouras C, Su JH, Kim R, Haier R, Cotman CW. Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome. Journal of Neuropathology and Experimental Neurology. 62: 917-26. PMID 14533781 DOI: 10.1093/Jnen/62.9.917  1
2003 Siwak CT, Tapp PD, Zicker SC, Murphey HL, Muggenburg BA, Head E, Cotman CW, Milgram NW. Locomotor activity rhythms in dogs vary with age and cognitive status. Behavioral Neuroscience. 117: 813-24. PMID 12931965 DOI: 10.1037/0735-7044.117.4.813  1
2003 Bi X, Head E, Cotman CW, Lynch G. Spatial patterns of mammalian brain aging: distribution of cathepsin D-immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease. The Journal of Comparative Neurology. 464: 371-81. PMID 12900930 DOI: 10.1002/cne.10795  1
2003 Torp R, Ottersen OP, Cotman CW, Head E. Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for beta-amyloid precursor protein processing. Neuroscience. 120: 291-300. PMID 12890502 DOI: 10.1016/S0306-4522(03)00320-8  1
2003 Garcia C, Chen MJ, Garza AA, Cotman CW, Russo-Neustadt A. The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity. Neuroscience. 119: 721-32. PMID 12809693 DOI: 10.1016/S0306-4522(03)00192-1  1
2003 Su JH, Anderson AJ, Cribbs DH, Tu C, Tong L, Kesslack P, Cotman CW. Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death. Neurobiology of Disease. 12: 182-93. PMID 12742739 DOI: 10.1016/S0969-9961(02)00019-0  1
2003 Ramsden M, Berchtold NC, Patrick Kesslak J, Cotman CW, Pike CJ. Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion. Brain Research. 971: 239-44. PMID 12706240 DOI: 10.1016/S0006-8993(03)02365-5  1
2003 Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science (New York, N.Y.). 300: 486-9. PMID 12702875 DOI: 10.1126/Science.1079469  1
2003 Cribbs DH, Ghochikyan A, Vasilevko V, Tran M, Petrushina I, Sadzikava N, Babikyan D, Kesslak P, Kieber-Emmons T, Cotman CW, Agadjanyan MG. Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid. International Immunology. 15: 505-14. PMID 12663680 DOI: 10.1093/intimm/dxg049  1
2003 Zhao M, Cribbs DH, Anderson AJ, Cummings BJ, Su JH, Wasserman AJ, Cotman CW. The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain. Neurochemical Research. 28: 307-18. PMID 12608703 DOI: 10.1023/A:1022337519035  1
2003 Tapp PD, Siwak CT, Estrada J, Head E, Muggenburg BA, Cotman CW, Milgram NW. Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 64-73. PMID 12551965 DOI: 10.1101/Lm.54403  1
2003 Head E, Milgram NW, Cotman CW. Neuropathology in ageing dogs | Neuropathologische Veränderungen bei alternden Hunden Praktische Tierarzt. 84: 192-195.  1
2002 Rohn TT, Rissman RA, Head E, Cotman CW. Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous. Drug News & Perspectives. 15: 549-557. PMID 12677194 DOI: 10.1358/dnp.2002.15.9.740233  1
2002 Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E. Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiology of Disease. 11: 341-54. PMID 12505426 DOI: 10.1006/nbdi.2002.0549  1
2002 Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Annals of the New York Academy of Sciences. 977: 45-64. PMID 12480733 DOI: 10.1111/J.1749-6632.2002.Tb04798.X  1
2002 Milgram NW, Head E, Muggenburg B, Holowachuk D, Murphey H, Estrada J, Ikeda-Douglas CJ, Zicker SC, Cotman CW. Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy. Neuroscience and Biobehavioral Reviews. 26: 679-95. PMID 12479842 DOI: 10.1016/S0149-7634(02)00039-8  1
2002 Cotman CW, Head E, Muggenburg BA, Zicker S, Milgram NW. Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction. Neurobiology of Aging. 23: 809-18. PMID 12392784 DOI: 10.1016/S0197-4580(02)00073-8  1
2002 Milgram NW, Zicker SC, Head E, Muggenburg BA, Murphey H, Ikeda-Douglas CJ, Cotman CW. Dietary enrichment counteracts age-associated cognitive dysfunction in canines. Neurobiology of Aging. 23: 737-45. PMID 12392778 DOI: 10.1016/S0197-4580(02)00020-9  1
2002 SantaCruz KS, Tasaki CS, Kim RC, Cotman CW. Brainstem and cortical Lewy bodies in patients presenting clinically with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 4: 11-7. PMID 12214014 DOI: 10.3233/Jad-2002-4102  1
2002 Head E, Lott IT, Cribbs DH, Cotman CW, Rohn TT. Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome. Neuroscience Letters. 330: 99-103. PMID 12213643 DOI: 10.1016/S0304-3940(02)00705-X  1
2002 Albert KA, Hemmings HC, Adamo AI, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P. Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Archives of General Psychiatry. 59: 705-12. PMID 12150646 DOI: 10.1001/Archpsyc.59.8.705  1
2002 Head E, Liu J, Hagen TM, Muggenburg BA, Milgram NW, Ames BN, Cotman CW. Oxidative damage increases with age in a canine model of human brain aging. Journal of Neurochemistry. 82: 375-81. PMID 12124438 DOI: 10.1046/J.1471-4159.2002.00969.X  1
2002 Berchtold NC, Kesslak JP, Cotman CW. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of Neuroscience Research. 68: 511-21. PMID 12111841 DOI: 10.1002/Jnr.10256  1
2002 Fillit HM, Butler RN, O'Connell AW, Albert MS, Birren JE, Cotman CW, Greenough WT, Gold PE, Kramer AF, Kuller LH, Perls TT, Sahagan BG, Tully T. Achieving and maintaining cognitive vitality with aging. Mayo Clinic Proceedings. 77: 681-96. PMID 12108606 DOI: 10.4065/77.7.681  1
2002 Cotman CW, Berchtold NC. Exercise: a behavioral intervention to enhance brain health and plasticity. Trends in Neurosciences. 25: 295-301. PMID 12086747 DOI: 10.1016/S0166-2236(02)02143-4  1
2002 Su JH, Kesslak JP, Head E, Cotman CW. Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain. Acta Neuropathologica. 104: 1-6. PMID 12070657 DOI: 10.1007/s00401-002-0548-2  1
2002 Chan AD, Nippak PM, Murphey H, Ikeda-Douglas CJ, Muggenburg B, Head E, Cotman CW, Milgram NW. Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility. Behavioral Neuroscience. 116: 443-54. PMID 12049325 DOI: 10.1037/0735-7044.116.3.443  1
2002 Soreghan B, Pike C, Kayed R, Tian W, Milton S, Cotman C, Glabe CG. The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties. Neuromolecular Medicine. 1: 81-94. PMID 12025818 DOI: 10.1385/Nmm:1:1:81  1
2002 Cotman CW, Engesser-Cesar C. Exercise enhances and protects brain function. Exercise and Sport Sciences Reviews. 30: 75-9. PMID 11991541 DOI: 10.1097/00003677-200204000-00006  1
2002 Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proceedings of the National Academy of Sciences of the United States of America. 99: 2356-61. PMID 11854529 DOI: 10.1073/Pnas.261709299  1
2002 Johnson JK, Shaw GL, Vuong M, Vuong S, Cotman CW. Short-Term Improvement on a Visual-Spatial Task After Music Listening in Alzheimer's Disease Activities, Adaptation & Aging. 26: 37-50. DOI: 10.1300/J016V26N03_03  0.01
2001 Berchtold NC, Kesslak JP, Pike CJ, Adlard PA, Cotman CW. Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus. The European Journal of Neuroscience. 14: 1992-2002. PMID 11860494 DOI: 10.1046/J.0953-816X.2001.01825.X  1
2001 Tong L, Shen H, Perreau VM, Balazs R, Cotman CW. Effects of exercise on gene-expression profile in the rat hippocampus. Neurobiology of Disease. 8: 1046-56. PMID 11741400 DOI: 10.1006/nbdi.2001.0427  1
2001 Rohn TT, Head E, Nesse WH, Cotman CW, Cribbs DH. Activation of caspase-8 in the Alzheimer's disease brain. Neurobiology of Disease. 8: 1006-16. PMID 11741396 DOI: 10.1006/Nbdi.2001.0449  1
2001 Shen H, Tong L, Balazs R, Cotman CW. Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus. Neuroscience. 107: 219-29. PMID 11731096 DOI: 10.1016/S0306-4522(01)00315-3  1
2001 Head E, Garzon-Rodriguez W, Johnson JK, Lott IT, Cotman CW, Glabe C. Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome. Neurobiology of Disease. 8: 792-806. PMID 11592849 DOI: 10.1006/nbdi.2001.0431  1
2001 Stoltzner SE, Berchtold NC, Cotman CW, Pike CJ. Estrogen regulates bcl-x expression in rat hippocampus. Neuroreport. 12: 2797-800. PMID 11588579 DOI: 10.1097/00001756-200109170-00009  1
2001 Nichol KE, Kim R, Cotman CW. Bcl-2 family protein behavior in frontotemporal dementia implies vascular involvement. Neurology. 56: S35-40. PMID 11402149 DOI: 10.1212/Wnl.56.Suppl_4.S35  1
2001 Brewer GJ, Espinosa J, McIlhaney MP, Pencek TP, Kesslak JP, Cotman C, Viel J, McManus DC. Culture and regeneration of human neurons after brain surgery. Journal of Neuroscience Methods. 107: 15-23. PMID 11389937 DOI: 10.1016/S0165-0270(01)00342-9  1
2001 Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW. Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Research. 898: 350-7. PMID 11306022 DOI: 10.1016/S0006-8993(01)02018-2  1
2001 Head E, Azizeh BY, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. Neurobiology of Disease. 8: 252-65. PMID 11300721 DOI: 10.1006/Nbdi.2000.0380  1
2001 Tong L, Thornton PL, Balazs R, Cotman CW. Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised. The Journal of Biological Chemistry. 276: 17301-6. PMID 11278679 DOI: 10.1074/jbc.M010450200  1
2001 Rohn TT, Wong SM, Cotman CW, Cribbs DH. 15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis. Neuroreport. 12: 839-43. PMID 11277593 DOI: 10.1097/00001756-200103260-00043  1
2001 Martin JA, Craft DK, Su JH, Kim RC, Cotman CW. Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion. Neurobiology of Aging. 22: 195-207. PMID 11182469 DOI: 10.1016/S0197-4580(00)00231-1  1
2001 Rohn TT, Head E, Su JH, Anderson AJ, Bahr BA, Cotman CW, Cribbs DH. Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. The American Journal of Pathology. 158: 189-98. PMID 11141492 DOI: 10.1016/S0002-9440(10)63957-0  1
2000 Cotman CW, Anderson AJ. The brain's microenvironment, early functional loss, and the conversion to Alzheimer's disease. Annals of the New York Academy of Sciences. 924: 112-6. PMID 11193787 DOI: 10.1111/J.1749-6632.2000.Tb05569.X  1
2000 Torp R, Head E, Cotman CW. Ultrastructural analyses of beta-amyloid in the aged dog brain: neuronal beta-amyloid is localized to the plasma membrane. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 801-10. PMID 11191714 DOI: 10.1016/S0278-5846(00)00107-X  1
2000 Head E, Thornton PL, Tong L, Cotman CW. Initiation and propagation of molecular cascades in human brain aging: insight from the canine model to promote successful aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 777-86. PMID 11191712 DOI: 10.1016/S0278-5846(00)00105-6  1
2000 Callahan H, Ikeda-Douglas C, Head E, Cotman CW, Milgram NW. Development of a protocol for studying object recognition memory in the dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 693-707. PMID 11191709 DOI: 10.1016/S0278-5846(00)00102-0  1
2000 Head E, Cotman CW, Milgram NW. Canine cognition, aging and neuropathology. Introduction. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 671-3. PMID 11191707 DOI: 10.1016/S0278-5846(00)00100-7  1
2000 Dick MB, Hsieh S, Dick-Muehlke C, Davis DS, Cotman CW. The variability of practice hypothesis in motor learning: does it apply to Alzheimer's disease? Brain and Cognition. 44: 470-89. PMID 11104538 DOI: 10.1006/brcg.2000.1206  1
2000 Russo-Neustadt AA, Beard RC, Huang YM, Cotman CW. Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience. 101: 305-12. PMID 11074154 DOI: 10.1016/S0306-4522(00)00349-3  1
2000 Johnson JK, Head E, Kim R, Starr A, Cotman CW. Topography, histology, and seminology in dementia Archives of Neurology. 57: 899-900. PMID 10867791 DOI: 10.1001/Archneur.57.6.899  1
2000 Cribbs DH, Azizeh BY, Cotman CW, LaFerla FM. Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide. Biochemistry. 39: 5988-94. PMID 10821670 DOI: 10.1021/bi000029f  1
2000 Rohn TT, Ivins KJ, Bahr BA, Cotman CW, Cribbs DH. A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis. Journal of Neurochemistry. 74: 2331-42. PMID 10820193 DOI: 10.1046/j.1471-4159.2000.0742331.x  1
2000 Ulas J, Satou T, Ivins KJ, Kesslak JP, Cotman CW, Balázs R. Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures. Glia. 30: 352-61. PMID 10797615 DOI: 10.1002/(SICI)1098-1136(200006)30:4<352::AID-GLIA40>3.0.CO;2-6  1
2000 Head E, McCleary R, Hahn FF, Milgram NW, Cotman CW. Region-specific age at onset of beta-amyloid in dogs. Neurobiology of Aging. 21: 89-96. PMID 10794853 DOI: 10.1016/S0197-4580(00)00093-2  1
2000 Azizeh BY, Head E, Ibrahim MA, Torp R, Tenner AJ, Kim RC, Lott IT, Cotman CW. Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs. Experimental Neurology. 163: 111-22. PMID 10785449 DOI: 10.1006/Exnr.2000.7359  1
2000 Su JH, Nichol KE, Sitch T, Sheu P, Chubb C, Miller BL, Tomaselli KJ, Kim RC, Cotman CW. DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia. Experimental Neurology. 163: 9-19. PMID 10785439 DOI: 10.1006/Exnr.2000.7340  1
2000 Torp R, Head E, Milgram NW, Hahn F, Ottersen OP, Cotman CW. Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains. Neuroscience. 96: 495-506. PMID 10717430 DOI: 10.1016/S0306-4522(99)00568-0  1
2000 Mulnard RA, Cotman CW, Kawas C, van Dyck CH, Sano M, Doody R, Koss E, Pfeiffer E, Jin S, Gamst A, Grundman M, Thomas R, Thal LJ. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. Jama. 283: 1007-15. PMID 10697060 DOI: 10.1001/Jama.283.8.1007  1
2000 Adams B, Chan A, Callahan H, Siwak C, Tapp D, Ikeda-Douglas C, Atkinson P, Head E, Cotman CW, Milgram NW. Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog. Behavioural Brain Research. 108: 47-56. PMID 10680756 DOI: 10.1016/S0166-4328(99)00132-1  1
2000 Sheu PCY, Cummings B, Cotman C, Chubb C, Hu L, Wang T, Johnson J, Mobley S, Stitch T, Inagaki Y. An object relational approach to biomedical database Proceedings - Ieee International Symposium On Bio-Informatics and Biomedical Engineering, Bibe 2000. 91-98. DOI: 10.1109/BIBE.2000.889594  1
2000 Mulnard RA, Cotman CW, Kawas C, Dyck CHv, Sano M, Doody R, Koss E, Pfeiffer E, Jin S, Gamst A, Grundman M, Thomas R. Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease: A Randomized Controlled Trial Obstetrical & Gynecological Survey. 439-440. DOI: 10.1097/00006254-200007000-00021  1
2000 Torp R, Azizeh BY, Head E, Cotman C. 5. Molecular dating of senile plaques in the brains of individuals with Down syndrome. Acta Neurologica Scandinavica. 102: 5-52. DOI: 10.1034/j.1600-0404.2000.00202-31.x  0.01
2000 Head E, Azizeh BY, Wong SM, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. C1Q and inflammation in Down syndrome pathogenesis Neurobiology of Aging. 21: 12. DOI: 10.1016/S0197-4580(00)82731-1  1
2000 Cotman CW, Anderson AJ, Cribbs DH. β-amyloid: An inert deposit comes alive Neurobiology of Aging. 21: 134. DOI: 10.1016/S0197-4580(00)82401-X  0.01
1999 Ivins KJ, Thornton PL, Rohn TT, Cotman CW. Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8. Neurobiology of Disease. 6: 440-9. PMID 10527810 DOI: 10.1006/nbdi.1999.0268  1
1999 Davis J, Cribbs DH, Cotman CW, Van Nostrand WE. Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 6: 157-64. PMID 10524279 DOI: 10.3109/13506129909007321  1
1999 Johnson JK, Head E, Kim R, Starr A, Cotman CW. Clinical and pathological evidence for a frontal variant of Alzheimer disease. Archives of Neurology. 56: 1233-9. PMID 10520939 DOI: 10.1001/Archneur.56.10.1233  1
1999 Kim D, Su J, Cotman CW. Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment. Brain Research. 839: 253-62. PMID 10519048 DOI: 10.1016/S0006-8993(99)01724-2  1
1999 Russo-Neustadt A, Beard RC, Cotman CW. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 679-82. PMID 10516964 DOI: 10.1016/S0893-133X(99)00059-7  1
1999 Deng G, Su JH, Ivins KJ, Van Houten B, Cotman CW. Bcl-2 facilitates recovery from DNA damage after oxidative stress. Experimental Neurology. 159: 309-18. PMID 10486199 DOI: 10.1006/exnr.1999.7145  1
1999 Berchtold NC, Oliff HS, Isackson P, Cotman CW. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain Research. Molecular Brain Research. 71: 11-22. PMID 10407182 DOI: 10.1016/S0169-328X(99)00137-0  1
1999 Fonseca MI, Head E, Velazquez P, Cotman CW, Tenner AJ. The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age. Experimental Neurology. 157: 277-88. PMID 10364440 DOI: 10.1006/Exnr.1999.7058  1
1999 Milgram NW, Adams B, Callahan H, Head E, Mackay B, Thirlwell C, Cotman CW. Landmark discrimination learning in the dog. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 54-61. PMID 10355524 DOI: 10.1101/Lm.6.1.54  1
1999 Leissring MA, Paul BA, Parker I, Cotman CW, LaFerla FM. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes. Journal of Neurochemistry. 72: 1061-8. PMID 10037477 DOI: 10.1046/J.1471-4159.1999.0721061.X  1
1999 Ivins KJ, Ivins JK, Sharp JP, Cotman CW. Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid. The Journal of Biological Chemistry. 274: 2107-12. PMID 9890971 DOI: 10.1074/Jbc.274.4.2107  1
1998 Ivins KJ, Bui ET, Cotman CW. Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis. Neurobiology of Disease. 5: 365-78. PMID 10069579 DOI: 10.1006/nbdi.1998.0228  1
1998 Su MY, Head E, Brooks WM, Wang Z, Muggenburg BA, Adam GE, Sutherland R, Cotman CW, Nalcioglu O. Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging. Neurobiology of Aging. 19: 479-85. PMID 9880050 DOI: 10.1016/S0197-4580(98)00081-5  1
1998 Head E, Callahan H, Muggenburg BA, Cotman CW, Milgram NW. Visual-discrimination learning ability and beta-amyloid accumulation in the dog. Neurobiology of Aging. 19: 415-25. PMID 9880044 DOI: 10.1016/S0197-4580(98)00084-0  1
1998 Johnson JK, Cotman CW, Tasaki CS, Shaw GL. Enhancement of spatial-temporal reasoning after a Mozart listening condition in Alzheimer's disease: a case study. Neurological Research. 20: 666-72. PMID 9864729 DOI: 10.1080/01616412.1998.11740582  1
1998 Eckert A, Cotman CW, Zerfass R, Hennerici M, Müller WE. Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered. Journal of Neural Transmission. Supplementum. 54: 259-67. PMID 9850934 DOI: 10.1007/978-3-7091-7508-8_25  1
1998 Torp R, Su JH, Deng G, Cotman CW. GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro. Neurobiology of Disease. 5: 245-52. PMID 9848094 DOI: 10.1006/nbdi.1998.0201  1
1998 Su JH, Cummings BJ, Cotman CW. Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites. Acta Neuropathologica. 96: 463-71. PMID 9829809 DOI: 10.1007/S004010050920  1
1998 Oliff HS, Berchtold NC, Isackson P, Cotman CW. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Brain Research. Molecular Brain Research. 61: 147-53. PMID 9795193 DOI: 10.1016/S0169-328X(98)00222-8  1
1998 Miller BL, Cummings J, Mishkin F, Boone K, Prince F, Ponton M, Cotman C. Emergence of artistic talent in frontotemporal dementia. Neurology. 51: 978-82. PMID 9781516 DOI: 10.1212/Wnl.51.4.978  1
1998 Kesslak JP, So V, Choi J, Cotman CW, Gomez-Pinilla F. Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behavioral Neuroscience. 112: 1012-9. PMID 9733207 DOI: 10.1037/0735-7044.112.4.1012  1
1998 Russo-Neustadt A, Zomorodian TJ, Cotman CW. Preserved cerebellar tyrosine hydroxylase-immunoreactive neuronal fibers in a behaviorally aggressive subgroup of Alzheimer's disease patients. Neuroscience. 87: 55-61. PMID 9722141 DOI: 10.1016/S0306-4522(98)00134-1  1
1998 Eckert A, Cotman CW, Zerfass R, Hennerici M, Müller WE. Enhanced vulnerability to apoptotic cell death in sporadic Alzheimer's disease. Neuroreport. 9: 2443-6. PMID 9721911 DOI: 10.1097/00001756-199808030-00003  1
1998 Stenger DA, Hickman JJ, Bateman KE, Ravenscroft MS, Ma W, Pancrazio JJ, Shaffer K, Schaffner AE, Cribbs DH, Cotman CW. Microlithographic determination of axonal/dendritic polarity in cultured hippocampal neurons. Journal of Neuroscience Methods. 82: 167-73. PMID 9700689 DOI: 10.1016/S0165-0270(98)00047-8  1
1998 Azizeh BY, Cribbs DH, Kreng VM, Cotman CW. Cross-linking of NCAM receptors on neurons induces programmed cell death. Brain Research. 796: 20-6. PMID 9689450 DOI: 10.1016/S0006-8993(98)00309-6  1
1998 Cotman CW, Hailer NP, Pfister KK, Soltesz I, Schachner M. Cell adhesion molecules in neural plasticity and pathology: similar mechanisms, distinct organizations? Progress in Neurobiology. 55: 659-69. PMID 9670224 DOI: 10.1016/S0301-0082(98)00025-2  1
1998 Sheetz MP, Pfister KK, Bulinski JC, Cotman CW. Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration. Progress in Neurobiology. 55: 577-94. PMID 9670219 DOI: 10.1016/S0301-0082(98)00021-5  1
1998 Johnson JK, McCleary R, Oshita MH, Cotman CW. Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles. Brain Research. 798: 18-24. PMID 9666062 DOI: 10.1016/S0006-8993(98)00363-1  1
1998 Berchtold NC, Cotman CW. Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s. Neurobiology of Aging. 19: 173-89. PMID 9661992 DOI: 10.1016/S0197-4580(98)00052-9  1
1998 Balázs R, Miller S, Chun Y, Cotman CW. Receptor-coupled phospholipase C and adenylyl cyclase function with different calcium pools in astrocytes. Neuroreport. 9: 1397-401. PMID 9631436 DOI: 10.1097/00001756-199805110-00027  1
1998 Balázs R, Miller S, Chun Y, O'Toole J, Cotman CW. Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture. Journal of Neurochemistry. 70: 2446-58. PMID 9603209 DOI: 10.1046/J.1471-4159.1998.70062446.X  1
1998 Cotman CW. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease. Neurobiology of Aging. 19: S29-32. PMID 9562464 DOI: 10.1016/S0197-4580(98)00042-6  0.01
1998 Ibrahim MA, Emerson JF, Cotman CW. Magnetic resonance imaging relaxation times and gadolinium-DTPA relaxivity values in human cerebrospinal fluid. Investigative Radiology. 33: 153-62. PMID 9525754 DOI: 10.1097/00004424-199803000-00005  1
1998 Cotman CW, Berchtold NC. Plasticity and growth factors injury response Mental Retardation and Developmental Disabilities Research Reviews. 4: 223-230. DOI: 10.1002/(Sici)1098-2779(1998)4:3<223::Aid-Mrdd10>3.0.Co;2-X  1
1998 Slater D, Healey G, Sheu P, Cotman CW, Su J, Wasserman A, Shankle R. Novel use of color computer vision methods for the quantification of neurons in 3-D brain tissue samples Proceedings of the Ieee International Conference On Systems, Man and Cybernetics. 5: 4411-4416.  1
1998 Scriabine A, Peters A, Cotman CW, Griffin WST, Pasinetti GM, Rothstein JD, Goldberg MP. Glial cells in aging and neurodegeneration. A satellite symposium to the 28(th) annual meeting of the society for neuroscience. Los Angeles, CA, November 7, 1998 Cns Drug Reviews. 4: 384-385.  1
1997 Su JH, Deng G, Cotman CW. Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain. Brain Research. 774: 193-9. PMID 9452208 DOI: 10.1016/S0006-8993(97)81703-9  1
1997 Satou T, Cummings BJ, Head E, Nielson KA, Hahn FF, Milgram NW, Velazquez P, Cribbs DH, Tenner AJ, Cotman CW. The progression of beta-amyloid deposition in the frontal cortex of the aged canine. Brain Research. 774: 35-43. PMID 9452189 DOI: 10.1016/S0006-8993(97)81684-8  1
1997 Su JH, Deng G, Cotman CW. Transneuronal degeneration in the spread of Alzheimer's disease pathology: immunohistochemical evidence for the transmission of tau hyperphosphorylation. Neurobiology of Disease. 4: 365-75. PMID 9440125 DOI: 10.1006/nbdi.1997.0164  1
1997 Major DE, Kesslak JP, Cotman CW, Finch CE, Day JR. Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA. Neurobiology of Aging. 18: 523-6. PMID 9390779 DOI: 10.1016/S0197-4580(97)00102-4  1
1997 Head E, Callahan H, Cummings BJ, Cotman CW, Ruehl WW, Muggenberg BA, Milgram NW. Open field activity and human interaction as a function of age and breed in dogs. Physiology & Behavior. 62: 963-71. PMID 9333188 DOI: 10.1016/S0031-9384(97)00198-4  1
1997 de Figueiredo RJ, Oten R, Su J, Cotman CW. Amyloid deposition in cerebrovascular angiopathy. Annals of the New York Academy of Sciences. 826: 463-71. PMID 9329725 DOI: 10.1111/J.1749-6632.1997.Tb48505.X  1
1997 Pike CJ, Ramezan-Arab N, Cotman CW. Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants. Journal of Neurochemistry. 69: 1601-11. PMID 9326289 DOI: 10.1046/J.1471-4159.1997.69041601.X  1
1997 Ulas J, Cotman CW. Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience. 79: 973-82. PMID 9219960 DOI: 10.1016/S0306-4522(97)00023-7  1
1997 Russo-Neustadt A, Cotman CW. Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5573-80. PMID 9204938 DOI: 10.1523/Jneurosci.17-14-05573.1997  1
1997 Donovan FM, Pike CJ, Cotman CW, Cunningham DD. Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5316-26. PMID 9204916 DOI: 10.1523/Jneurosci.17-14-05316.1997  0.12
1997 Balázs R, Miller S, Romano C, de Vries A, Chun Y, Cotman CW. Metabotropic glutamate receptor mGluR5 in astrocytes: pharmacological properties and agonist regulation. Journal of Neurochemistry. 69: 151-63. PMID 9202306 DOI: 10.1046/J.1471-4159.1997.69010151.X  1
1997 Cotman CW. The beta-amyloid peptide, peptide self-assembly, and the emergence of biological activities. A new principle in peptide function and the induction of neuropathology. Annals of the New York Academy of Sciences. 814: 1-16. PMID 9160955 DOI: 10.1111/j.1749-6632.1997.tb46140.x  0.01
1997 Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. The New England Journal of Medicine. 336: 1216-22. PMID 9110909 DOI: 10.1056/Nejm199704243361704  1
1997 Cribbs DH, Pike CJ, Weinstein SL, Velazquez P, Cotman CW. All-D-enantiomers of beta-amyloid exhibit similar biological properties to all-L-beta-amyloids. The Journal of Biological Chemistry. 272: 7431-6. PMID 9054444 DOI: 10.1074/Jbc.272.11.7431  1
1997 Su JH, Deng G, Cotman CW. Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. Journal of Neuropathology and Experimental Neurology. 56: 86-93. PMID 8990132 DOI: 10.1097/00005072-199701000-00009  1
1997 Gómez-Pinilla F, Miller S, Choi J, Cotman CW. Heparan sulfate potentiates the autocrine action of basic fibroblast growth factor in astrocytes: an in vivo and in vitro study. Neuroscience. 76: 137-45. PMID 8971766 DOI: 10.1016/S0306-4522(96)00327-2  1
1997 Donovan FM, Pike CJ, Cotman CW, Cunningham DD. Thrombin Induces Apoptosis in Cultured Neurons and Astrocytes via a Pathway Requiring Tyrosine Kinase and RhoA Activities The Journal of Neuroscience. 17: 5316-5326. DOI: 10.1523/JNEUROSCI.17-14-05316.1997  0.01
1997 Pike CJ, Ramezan-Arab N, Cotman CW. β-Amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants Journal of Neurochemistry. 69: 1601-1611.  1
1996 Cummings BJ, Pike CJ, Shankle R, Cotman CW. Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiology of Aging. 17: 921-33. PMID 9363804 DOI: 10.1016/S0197-4580(96)00170-4  1
1996 Nielson KA, Cummings BJ, Cotman CW. Constructional apraxia in Alzheimer's disease correlates with neuritic neuropathology in occipital cortex. Brain Research. 741: 284-93. PMID 9001734 DOI: 10.1016/S0006-8993(96)00983-3  1
1996 Su JH, Cummings BJ, Cotman CW. Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments. Brain Research. 739: 79-87. PMID 8955927 DOI: 10.1016/S0006-8993(96)00811-6  1
1996 Cotman CW, Su JH. Mechanisms of neuronal death in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 6: 493-506. PMID 8944319 DOI: 10.1111/J.1750-3639.1996.Tb00878.X  1
1996 Deng G, Pike CJ, Cotman CW. Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells. Febs Letters. 397: 50-4. PMID 8941712 DOI: 10.1016/S0014-5793(96)01142-8  1
1996 Deng G, Su JH, Cotman CW. Gene expression of Alzheimer-associated presenilin-2 in the frontal cortex of Alzheimer and aged control brain. Febs Letters. 394: 17-20. PMID 8925918 DOI: 10.1016/0014-5793(96)00922-2  1
1996 Cribbs DH, Kreng VM, Anderson AJ, Cotman CW. Cross-linking of concanavalin A receptors on cortical neurons induces programmed cell death. Neuroscience. 75: 173-85. PMID 8923532 DOI: 10.1016/0306-4522(96)80001-P  1
1996 UÅ‚as J, Cotman CW. Dopaminergic denervation of striatum results in elevated expression of NR2A subunit. Neuroreport. 7: 1789-93. PMID 8905666  1
1996 Cribbs DH, Chen LS, Cotman CW, LaFerla FM. Injury induces presenilin-1 gene expression in mouse brain. Neuroreport. 7: 1773-6. PMID 8905662 DOI: 10.1097/00001756-199607290-00016  1
1996 Cotman CW, Tenner AJ, Cummings BJ. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiology of Aging. 17: 723-31. PMID 8892345 DOI: 10.1016/0197-4580(96)00117-0  1
1996 Pike CJ, Balázs R, Cotman CW. Attenuation of beta-amyloid neurotoxicity in vitro by potassium-induced depolarization. Journal of Neurochemistry. 67: 1774-7. PMID 8858966 DOI: 10.1046/J.1471-4159.1996.67041774.X  1
1996 Miller S, Sehati N, Romano C, Cotman CW. Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5. Journal of Neurochemistry. 67: 1435-47. PMID 8858925 DOI: 10.1046/J.1471-4159.1996.67041435.X  1
1996 Neeper SA, Gómez-Pinilla F, Choi J, Cotman CW. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Research. 726: 49-56. PMID 8836544 DOI: 10.1016/0006-8993(96)00273-9  1
1996 Cummings BJ, Satou T, Head E, Milgram NW, Cole GM, Savage MJ, Podlisny MB, Selkoe DJ, Siman R, Greenberg BD, Cotman CW. Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs. Neurobiology of Aging. 17: 653-9. PMID 8832640 DOI: 10.1016/0197-4580(96)00062-0  1
1996 Dick MB, Shankle RW, Beth RE, Dick-Muehlke C, Cotman CW, Kean ML. Acquisition and long-term retention of a gross motor skill in Alzheimer's disease patients under constant and varied practice conditions. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences. 51: P103-11. PMID 8785686 DOI: 10.1093/Geronb/51B.2.P103  1
1996 Anderson AJ, Su JH, Cotman CW. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1710-9. PMID 8774439 DOI: 10.1523/Jneurosci.16-05-01710.1996  1
1996 Cummings BJ, Head E, Ruehl W, Milgram NW, Cotman CW. The canine as an animal model of human aging and dementia. Neurobiology of Aging. 17: 259-68. PMID 8744407 DOI: 10.1016/0197-4580(95)02060-8  1
1996 Su JH, Satou T, Anderson AJ, Cotman CW. Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease. Neuroreport. 7: 437-40. PMID 8730800 DOI: 10.1097/00001756-199601310-00015  1
1996 Nielson KA, Nolan JH, Berchtold NC, Sandman CA, Mulnard RA, Cotman CW. Apolipoprotein-E genotyping of diabetic dementia patients: is diabetes rare in Alzheimer's disease? Journal of the American Geriatrics Society. 44: 897-904. PMID 8708297 DOI: 10.1111/J.1532-5415.1996.Tb01857.X  1
1996 Cummings BJ, Head E, Afagh AJ, Milgram NW, Cotman CW. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine. Neurobiology of Learning and Memory. 66: 11-23. PMID 8661247 DOI: 10.1006/Nlme.1996.0039  1
1996 Pike CJ, Ramezan-Arab N, Miller S, Cotman CW. beta-Amyloid increases enzyme activity and protein levels of glutamine synthetase in cultured astrocytes. Experimental Neurology. 139: 167-71. PMID 8635563 DOI: 10.1006/Exnr.1996.0091  1
1996 Pike CJ, Vaughan PJ, Cunningham DD, Cotman CW. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. Journal of Neurochemistry. 66: 1374-82. PMID 8627288 DOI: 10.1046/J.1471-4159.1996.66041374.X  1
1996 Afagh A, Cummings BJ, Cribbs DH, Cotman CW, Tenner AJ. Localization and cell association of C1q in Alzheimer's disease brain. Experimental Neurology. 138: 22-32. PMID 8593893 DOI: 10.1006/Exnr.1996.0043  1
1996 Anderson A, Sue J, Satou T, Cotman C. 732 Ref-1 immunoreactivity in Alzheimer's disease Neurobiology of Aging. 17: S182. DOI: 10.1016/S0197-4580(96)80734-2  0.04
1996 Cummings B, Pike C, Cotman C. 722 Multiple neuropathological variables are correlated with the level of cognitive impairment in Alzheimer's disease Neurobiology of Aging. 17: S179. DOI: 10.1016/S0197-4580(96)80724-X  0.01
1996 Pike C, Cotman C. 423 β-Amyloid neurotoxicity in vitro: Examination of potential contributions by oxidative pathways Neurobiology of Aging. 17: S106. DOI: 10.1016/S0197-4580(96)80425-8  0.01
1996 Cummings BJ, Pike CJ, Cotman CW. Author's response to commentaries Neurobiology of Aging. 17: 945-947. DOI: 10.1016/S0197-4580(96)00171-6  0.01
1996 Balazs R, Miller S, Romano C, Chun Y, de Vries A, Cotman C. Metabotropic glutamate receptors in cerebral cortical astrocytes: pharmacological properties of mGluR5 and interaction between PLC-and adenylate cyclase (AC)-coupled transduction systems Neuropharmacology. 35: A2. DOI: 10.1016/0028-3908(96)84653-3  0.01
1995 Dick MB, Nielson KA, Beth RE, Shankle WR, Cotman CW. Acquisition and long-term retention of a fine motor skill in Alzheimer's disease. Brain and Cognition. 29: 294-306. PMID 8838387 DOI: 10.1006/Brcg.1995.1283  1
1995 Shankle WR, Nielson KA, Cotman CW. Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. Alzheimer Disease and Associated Disorders. 9: 233-7. PMID 8749613 DOI: 10.1097/00002093-199500940-00010  1
1995 Woods AG, Cribbs DH, Whittemore ER, Cotman CW. Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons. Brain Research. 697: 53-62. PMID 8593595 DOI: 10.1016/0006-8993(95)00775-L  1
1995 Satou T, Cummings BJ, Cotman CW. Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity. Brain Research. 697: 35-43. PMID 8593592 DOI: 10.1016/0006-8993(95)00748-F  1
1995 Ruehl WW, Bruyette DS, DePaoli A, Cotman CW, Head E, Milgram NW, Cummings BJ. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy. Progress in Brain Research. 106: 217-25. PMID 8584657 DOI: 10.1016/S0079-6123(08)61218-2  1
1995 Loo DT, Althoen MC, Cotman CW. Differentiation of serum-free mouse embryo cells into astrocytes is accompanied by induction of glutamine synthetase activity. Journal of Neuroscience Research. 42: 184-91. PMID 8568918 DOI: 10.1002/jnr.490420205  1
1995 Head E, Mehta R, Hartley J, Kameka M, Cummings BJ, Cotman CW, Ruehl WW, Milgram NW. Spatial learning and memory as a function of age in the dog. Behavioral Neuroscience. 109: 851-8. PMID 8554710 DOI: 10.1037//0735-7044.109.5.851  1
1995 Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW, Cunningham DD. Decreases in protease nexins in Alzheimer's disease brain. Neurobiology of Aging. 16: 557-62. PMID 8544905 DOI: 10.1016/0197-4580(95)00060-R  1
1995 Gómez-Pinilla F, Vu L, Cotman CW. Regulation of astrocyte proliferation by FGF-2 and heparan sulfate in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2021-9. PMID 7891149 DOI: 10.1523/Jneurosci.15-03-02021.1995  1
1995 Neeper SA, Gómez-Pinilla F, Choi J, Cotman C. Exercise and brain neurotrophins Nature. 373: 109-109. PMID 7816089 DOI: 10.1038/373109A0  1
1995 Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. Journal of Neurochemistry. 64: 253-65. PMID 7798921 DOI: 10.1046/J.1471-4159.1995.64010253.X  1
1995 Kesslak JP, Yuan D, Neeper S, Cotman CW. Vulnerability of the hippocampus to kainate excitotoxicity in the aged, mature and young adult rat. Neuroscience Letters. 188: 117-20. PMID 7792054 DOI: 10.1016/0304-3940(95)11415-S  1
1995 Pike CJ, Cummings BJ, Cotman CW. Early association of reactive astrocytes with senile plaques in Alzheimer's disease. Experimental Neurology. 132: 172-9. PMID 7789457 DOI: 10.1016/0014-4886(95)90022-5  1
1995 deFigueiredo RJ, Shankle WR, Maccato A, Dick MB, Mundkur P, Mena I, Cotman CW. Neural-network-based classification of cognitively normal, demented, Alzheimer disease and vascular dementia from single photon emission with computed tomography image data from brain. Proceedings of the National Academy of Sciences of the United States of America. 92: 5530-4. PMID 7777543 DOI: 10.1073/Pnas.92.12.5530  1
1995 Defigueiredo RJ, Cummings BJ, Mundkur PY, Cotman CW. Color image analysis in neuroanatomical research: application to senile plaque subtype quantification in Alzheimer's disease. Neurobiology of Aging. 16: 211-23. PMID 7777139 DOI: 10.1016/0197-4580(94)00151-0  1
1995 Pike CJ, Cotman CW. Calretinin-immunoreactive neurons are resistant to beta-amyloid toxicity in vitro. Brain Research. 671: 293-8. PMID 7743217 DOI: 10.1016/0006-8993(94)01354-K  1
1995 Korotzer AR, Whittemore ER, Cotman CW. Differential regulation by beta-amyloid peptides of intracellular free Ca2+ concentration in cultured rat microglia. European Journal of Pharmacology. 288: 125-30. PMID 7720773 DOI: 10.1016/0922-4106(95)90006-3  1
1995 Whittemore ER, Loo DT, Watt JA, Cotman CW. A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture. Neuroscience. 67: 921-32. PMID 7675214 DOI: 10.1016/0306-4522(95)00108-U  0.04
1995 Miller S, Romano C, Cotman CW. Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6103-9. PMID 7666194 DOI: 10.1523/Jneurosci.15-09-06103.1995  1
1995 Gómez-Pinilla F, van der Wal EA, Cotman CW. Possible coordinated gene expressions for FGF receptor, FGF-5, and FGF-2 following seizures. Experimental Neurology. 133: 164-74. PMID 7649223 DOI: 10.1006/Exnr.1995.1019  1
1995 Vaughan PJ, Pike CJ, Cotman CW, Cunningham DD. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5389-401. PMID 7623161 DOI: 10.1523/Jneurosci.15-07-05389.1995  1
1995 Davis-Salinas J, Saporito-Irwin SM, Cotman CW, Van Nostrand WE. Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. Journal of Neurochemistry. 65: 931-4. PMID 7616257 DOI: 10.1046/J.1471-4159.1995.65020931.X  1
1995 Miller S, Kesslak JP, Romano C, Cotman CW. Roles of metabotropic glutamate receptors in brain plasticity and pathology. Annals of the New York Academy of Sciences. 757: 460-74. PMID 7611703 DOI: 10.1111/J.1749-6632.1995.Tb17506.X  1
1995 Cotman CW, Anderson AJ. A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Molecular Neurobiology. 10: 19-45. PMID 7598831 DOI: 10.1007/Bf02740836  1
1995 Pike CJ, Overman MJ, Cotman CW. Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro. The Journal of Biological Chemistry. 270: 23895-8. PMID 7592576 DOI: 10.1074/Jbc.270.41.23895  1
1995 Araujo DM, Cotman CW. Differential effects of interleukin-1 beta and interleukin-2 on glia and hippocampal neurons in culture. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 13: 201-12. PMID 7572276 DOI: 10.1016/0736-5748(94)00072-B  0.01
1995 Anderson AJ, Pike CJ, Cotman CW. Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis. Journal of Neurochemistry. 65: 1487-98. PMID 7561842 DOI: 10.1046/J.1471-4159.1995.65041487.X  1
1995 Korotzer AR, Watt J, Cribbs D, Tenner AJ, Burdick D, Glabe C, Cotman CW. Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia. Experimental Neurology. 134: 214-21. PMID 7556541 DOI: 10.1006/Exnr.1995.1051  1
1995 Cummings BJ, Cotman CW. Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity. Lancet. 346: 1524-8. PMID 7491048 DOI: 10.1016/S0140-6736(95)92053-6  1
1994 Anderson AJ, Cummings BJ, Cotman CW. Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Experimental Neurology. 125: 286-95. PMID 8313943 DOI: 10.1006/Exnr.1994.1031  1
1994 Weiss JH, Pike CJ, Cotman CW. Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture. Journal of Neurochemistry. 62: 372-5. PMID 8263540 DOI: 10.1046/J.1471-4159.1994.62010372.X  1
1994 Su JH, Cummings BJ, Cotman CW. Subpopulations of dystrophic neurites [correction of neuritis] in Alzheimer's brain with distinct immunocytochemical and argentophilic characteristics. Brain Research. 637: 37-44. PMID 8180819 DOI: 10.1016/0006-8993(94)91214-9  1
1994 Jiang H, Burdick D, Glabe CG, Cotman CW, Tenner AJ. beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. Journal of Immunology (Baltimore, Md. : 1950). 152: 5050-9. PMID 8176223  1
1994 Van Der Wal EA, Gómez-Pinilla F, Cotman CW. Seizure-associated induction of basic fibroblast growth factor and its receptor in the rat brain. Neuroscience. 60: 311-23. PMID 8072686 DOI: 10.1016/0306-4522(94)90245-3  1
1994 Bridges RJ, Lovering FE, Koch H, Cotman CW, Chamberlin AR. A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate. Neuroscience Letters. 174: 193-7. PMID 7970177 DOI: 10.1016/0304-3940(94)90019-1  1
1994 UÅ‚as J, Weihmuller FB, Brunner LC, Joyce JN, Marshall JF, Cotman CW. Selective increase of NMDA-sensitive glutamate binding in the striatum of Parkinson's disease, Alzheimer's disease, and mixed Parkinson's disease/Alzheimer's disease patients: an autoradiographic study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6317-24. PMID 7965038 DOI: 10.1523/Jneurosci.14-11-06317.1994  1
1994 Whittemore ER, Loo DT, Cotman CW. Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons. Neuroreport. 5: 1485-8. PMID 7948844 DOI: 10.1097/00001756-199407000-00019  1
1994 Pike CJ, Cummings BJ, Monzavi R, Cotman CW. Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience. 63: 517-31. PMID 7891862 DOI: 10.1016/0306-4522(94)90547-9  1
1994 Miller S, Bridges RJ, Chamberlin AR, Cotman CW. Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes. European Journal of Pharmacology. 269: 235-41. PMID 7851499 DOI: 10.1016/0922-4106(94)90091-4  1
1994 Cotman CW, Whittemore ER, Watt JA, Anderson AJ, Loo DT. Possible role of apoptosis in Alzheimer's disease. Annals of the New York Academy of Sciences. 747: 36-49. PMID 7847684 DOI: 10.1111/J.1749-6632.1994.Tb44400.X  1
1994 Gómez-Pinilla F, Lee JW, Cotman CW. Distribution of basic fibroblast growth factor in the developing rat brain. Neuroscience. 61: 911-23. PMID 7838387 DOI: 10.1016/0306-4522(94)90412-X  1
1994 Smyth MD, Kesslak JP, Cummings BJ, Cotman CW. Analysis of brain injury following intrahippocampal administration of beta-amyloid in streptozotocin-treated rats. Neurobiology of Aging. 15: 153-9. PMID 7838285 DOI: 10.1016/0197-4580(94)90106-6  1
1994 Watt JA, Pike CJ, Walencewicz-Wasserman AJ, Cotman CW. Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons. Brain Research. 661: 147-56. PMID 7834365 DOI: 10.1016/0006-8993(94)91191-6  1
1994 Smyth MD, Cribbs DH, Tenner AJ, Shankle WR, Dick M, Kesslak JP, Cotman CW. Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state. Neurobiology of Aging. 15: 609-14. PMID 7824052 DOI: 10.1016/0197-4580(94)00055-7  1
1994 Vaughan PJ, Su J, Cotman CW, Cunningham DD. Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Research. 668: 160-70. PMID 7704602 DOI: 10.1016/0006-8993(94)90521-5  1
1994 Cotman CW. Report of Alzheimer's disease Working Group A. Neurobiology of Aging. 15: S17-22. PMID 7700445 DOI: 10.1016/0197-4580(94)90161-9  0.01
1994 Su JH, Anderson AJ, Cummings BJ, Cotman CW. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport. 5: 2529-33. PMID 7696596 DOI: 10.1097/00001756-199412000-00031  1
1994 Su JH, Cummings BJ, Cotman CW. Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites. Neuroreport. 5: 2358-62. PMID 7533559 DOI: 10.1097/00001756-199411000-00037  1
1994 Loo DT, Althoen MC, Cotman CW. Down regulation of nestin by TGF-beta or serum in SFME cells accompanies differentiation into astrocytes. Neuroreport. 5: 1585-8. PMID 7529590 DOI: 10.1097/00001756-199408150-00011  1
1994 Van Nostrand WE, Rozemuller AJM, Chung R, Cotman CW, Saporito-Irwin SM. Amyloid βprotein precursor in cultured leptomeningeal smooth muscle cells Amyloid. 1: 1-7. DOI: 10.3109/13506129409148618  1
1994 Hickman JJ, Bhatia SK, Quong JN, Shoen P, Stenger DA, Pike CJ, Cotman CW. Rational pattern design for in vitro cellular networks using surface photochemistry Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 12: 607-616. DOI: 10.1116/1.578844  1
1993 Kahle JS, UÅ‚as J, Cotman CW. Increased sensitivity to adenosine in the rat dentate gyrus molecular layer two weeks after partial entorhinal lesions. Brain Research. 609: 201-10. PMID 8508304 DOI: 10.1016/0006-8993(93)90874-M  1
1993 Russell MJ, Cummings BJ, Profitt BF, Wysocki CJ, Gilbert AN, Cotman CW. Life span changes in the verbal categorization of odors. Journal of Gerontology. 48: P49-53. PMID 8473697 DOI: 10.1093/Geronj/48.2.P49  1
1993 Pike CJ, Burdick D, Walencewicz AJ, Glabe CG, Cotman CW. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 1676-87. PMID 8463843 DOI: 10.1523/Jneurosci.13-04-01676.1993  1
1993 Gómez-Pinilla F, Cotman CW. Distribution of fibroblast growth factor 5 mRNA in the rat brain: an in situ hybridization study. Brain Research. 606: 79-86. PMID 8462006 DOI: 10.1016/0006-8993(93)91572-A  0.12
1993 Magnusson KR, Cotman CW. Effects of aging on NMDA and MK801 binding sites in mice. Brain Research. 604: 334-7. PMID 8457861 DOI: 10.1016/0006-8993(93)90386-2  0.01
1993 van der Wal EA, Gómez-Pinilla F, Cotman CW. Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies. Neuroreport. 4: 69-72. PMID 8453039 DOI: 10.1097/00001756-199301000-00018  0.08
1993 Ułas J, Brunner LC, Nguyen L, Cotman CW. Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: a quantitative autoradiographic study. Neuroscience. 52: 843-54. PMID 8450977 DOI: 10.1016/0306-4522(93)90533-L  0.04
1993 Araujo DM, Cotman CW. Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors. Brain Research. 600: 49-55. PMID 8422590 DOI: 10.1016/0006-8993(93)90400-H  0.01
1993 Neal JH, Cotman CW. Human brain tumor cyst fluid is mitogenic for primary astrocytes in culture. Neurosurgery. 32: 95-8; discussion 98-. PMID 8421562 DOI: 10.1227/00006123-199301000-00014  0.01
1993 Cotman CW, Pike CJ, Cummings BJ. Adaptive versus pathological plasticity. Possible contributions to age-related dementia Advances in Neurology. 59: 35-45. PMID 8420121  1
1993 Berkman LF, Seeman TE, Albert M, Blazer D, Kahn R, Mohs R, Finch C, Schneider E, Cotman C, McClearn G, Nesselroade J, Featherman D, Garmezy N, McKhann G, Brim G, et al. High, usual and impaired functioning in community-dwelling older men and women: Findings from the MacArthur Foundation Research Network on successful aging Journal of Clinical Epidemiology. 46: 1129-1140. PMID 8410098 DOI: 10.1016/0895-4356(93)90112-E  1
1993 Miller S, Bridges RJ, Cotman CW. Stimulation of phosphoinositide hydrolysis by trans-(+/-)-ACPD is greatly enhanced when astrocytes are cultured in a serum-free defined medium. Brain Research. 618: 175-8. PMID 8402173 DOI: 10.1016/0006-8993(93)90443-Q  1
1993 Kahle JS, Cotman CW. Adenosine, L-AP4, and baclofen modulation of paired-pulse potentiation in the dentate gyrus: interstimulus interval-dependent pharmacology. Experimental Brain Research. 94: 97-104. PMID 8392942 DOI: 10.1007/BF00230473  1
1993 Magnusson KR, Cotman CW. Age-related changes in excitatory amino acid receptors in two mouse strains. Neurobiology of Aging. 14: 197-206. PMID 8391661 DOI: 10.1016/0197-4580(93)90001-R  1
1993 Ułas J, Cotman CW. Excitatory amino acid receptors in schizophrenia. Schizophrenia Bulletin. 19: 105-17. PMID 8383875 DOI: 10.1093/SCHBUL/19.1.105  0.01
1993 Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proceedings of the National Academy of Sciences of the United States of America. 90: 7951-5. PMID 8367446 DOI: 10.1073/Pnas.90.17.7951  1
1993 Vijayan VK, Zhou SS, Russell MJ, Geddes J, Ellis W, Cotman CW. Perineuronal satellitosis in the human hippocampal formation. Hippocampus. 3: 239-50. PMID 8353607 DOI: 10.1002/hipo.450030215  1
1993 Cummings BJ, Su JH, Cotman CW, White R, Russell MJ. Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease. Neurobiology of Aging. 14: 547-60. PMID 8295657 DOI: 10.1016/0197-4580(93)90038-D  1
1993 Cummings BJ, Su JH, Cotman CW. Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease. Experimental Neurology. 124: 315-25. PMID 8287930 DOI: 10.1006/exnr.1993.1202  1
1993 Braak H, Braak E. Entorhinal-hippocampal interaction in mnestic disorders. Hippocampus. 3: 239-46. PMID 8287101 DOI: 10.1002/hipo.450030215  0.01
1993 Wagner SL, Van Nostrand WE, Lau AL, Farrow JS, Suzuki M, Bartus RT, Schuppek R, Nguyen A, Cotman CW, Cunningham DD. Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Research. 626: 90-8. PMID 8281456 DOI: 10.1016/0006-8993(93)90567-7  1
1993 Su JH, Cummings BJ, Cotman CW. Identification and distribution of axonal dystrophic neurites in Alzheimer's disease. Brain Research. 625: 228-37. PMID 8275305 DOI: 10.1016/0006-8993(93)91063-X  1
1993 Korotzer AR, Pike CJ, Cotman CW. beta-Amyloid peptides induce degeneration of cultured rat microglia. Brain Research. 624: 121-5. PMID 8252383 DOI: 10.1016/0006-8993(93)90068-X  1
1993 Pike CJ, Cotman CW. Cultured GABA-immunoreactive neurons are resistant to toxicity induced by beta-amyloid. Neuroscience. 56: 269-74. PMID 8247260 DOI: 10.1016/0306-4522(93)90331-9  1
1993 Stenger DA, Pike CJ, Hickman JJ, Cotman CW. Surface determinants of neuronal survival and growth on self-assembled monolayers in culture. Brain Research. 630: 136-47. PMID 8118680 DOI: 10.1016/0006-8993(93)90651-3  1
1993 Kahle JS, Cotman CW. Synaptic reorganization in the hippocampus: an electrophysiological analysis. Annals of the New York Academy of Sciences. 702: 61-74. PMID 8109878 DOI: 10.1111/J.1749-6632.1993.Tb17242.X  1
1993 Whittemore ER, Korotzer AR, Etebari A, Cotman CW. Carbachol increases intracellular free calcium in cultured rat microglia. Brain Research. 621: 59-64. PMID 8106116 DOI: 10.1016/0006-8993(93)90297-Z  1
1993 Kahle JS, Cotman CW. L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices. The Journal of Pharmacology and Experimental Therapeutics. 266: 207-15. PMID 8101217  1
1993 Wu J, Buchsbaum MS, Moy K, Denlea N, Kesslak P, Tseng H, Plosnaj D, Hetu M, Potkin S, Bracha S. Olfactory memory in unmedicated schizophrenics. Schizophrenia Research. 9: 41-7. PMID 8068050 DOI: 10.1016/0920-9964(93)90008-7  1
1993 UÅ‚as J, Nguyen L, Cotman CW. Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex. Neuroreport. 4: 1049-51. PMID 7902135 DOI: 10.1097/00001756-199308000-00014  1
1993 Su JH, Cummings BJ, Cotman CW. Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease. Neuroscience. 51: 801-13. PMID 1488123 DOI: 10.1016/0306-4522(92)90521-3  0.16
1993 Neal JH, Cotman CW. Human Brain Tumor Cyst Fluid Is Mitogenic for Primary Astrocytes in Culture Neurosurgery. 32: 95???99. DOI: 10.1097/00006123-199301000-00014  0.01
1992 Geddes JW, Cotman CW. Plasticity in Alzheimer's disease: too much or not enough? Neurobiology of Aging. 12: 330-3; discussion 35. PMID 1961362 DOI: 10.1016/0197-4580(91)90011-8  0.04
1992 Cotman CW, Gómez-Pinilla F. Basic fibroblast growth factor in the mature brain and its possible role in Alzheimer's disease. Annals of the New York Academy of Sciences. 638: 221-31. PMID 1785803 DOI: 10.1111/j.1749-6632.1991.tb49033.x  0.08
1992 Araujo DM, Cotman CW. Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Research. 569: 141-5. PMID 1611474 DOI: 10.1016/0006-8993(92)90380-R  0.01
1992 Emerich DF, Black BA, Kesslak JP, Cotman CW, Walsh TJ. Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A. Brain Research Bulletin. 28: 219-26. PMID 1596741 DOI: 10.1016/0361-9230(92)90182-W  1
1992 Taube JS, Kesslak JP, Cotman CW. Lesions of the rat postsubiculum impair performance on spatial tasks. Behavioral and Neural Biology. 57: 131-43. PMID 1586352 DOI: 10.1016/0163-1047(92)90629-I  1
1992 Van Nosthand WE, Wagner SL, Rodman Shankle W, Farrow JS, Dick M, Rozemuller JM, Kuiper MA, Wolters EC, Zimmerman J, Cotman CW, Cunningham DD. Decreased levels of soluble amyloid β-protein precursor in cerebrospinal fluid of live Alzheimer disease patients Proceedings of the National Academy of Sciences of the United States of America. 89: 2551-2555. PMID 1557359 DOI: 10.1073/PNAS.89.7.2551  1
1992 Koh JY, Cotman CW. Programmed cell death: its possible contribution to neurotoxicity mediated by calcium channel antagonists Brain Research. 587: 233-240. PMID 1525659 DOI: 10.1016/0006-8993(92)91002-V  1
1992 Weihmuller FB, Ulas J, Nguyen L, Cotman CW, Marshall JF. Elevated NMDA receptors in parkinsonian striatum. Neuroreport. 3: 977-80. PMID 1482768 DOI: 10.1097/00001756-199211000-00007  1
1992 Cotman CW, Pike CJ, Copani A. β-Amyloid neurotoxicity: A discussion of in vitro findings Neurobiology of Aging. 13: 587-590. PMID 1461347 DOI: 10.1016/0197-4580(92)90060-B  1
1992 Cummings BJ, Yee GJ, Cotman CW. bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy. Brain Research. 591: 271-6. PMID 1446240 DOI: 10.1016/0006-8993(92)91707-L  0.01
1992 Kammesheidt A, Boyce FM, Spanoyannis AF, Cummings BJ, Ortegon M, Cotman C, Vaught JL, Neve RL. Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain Proceedings of the National Academy of Sciences of the United States of America. 89: 10857-10861. PMID 1438289 DOI: 10.1073/Pnas.89.22.10857  1
1992 Gómez-Pinilla F, Cotman CW. Transient lesion-induced increase of basic fibroblast growth factor and its receptor in layer VIb (subplate cells) of the adult rat cerebral cortex. Neuroscience. 49: 771-80. PMID 1436480 DOI: 10.1016/0306-4522(92)90355-6  0.08
1992 Bridges RJ, Hatalski CG, Shim SN, Cummings BJ, Vijayan V, Kundi A, Cotman CW. Gliotoxic actions of excitatory amino acids. Neuropharmacology. 31: 899-907. PMID 1436396 DOI: 10.1016/0028-3908(92)90128-C  1
1992 Pike CJ, Cummings BJ, Cotman CW. µ-Amyloid induces neuritic dystrophy in vitro: Similarities with alzherimer pathology Neuroreport. 3: 769-772. PMID 1421135 DOI: 10.1097/00001756-199209000-00012  1
1992 Ułas J, Brunner LC, Geddes JW, Choe W, Cotman CW. N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease Neuroscience. 49: 45-61. PMID 1407551 DOI: 10.1016/0306-4522(92)90075-D  1
1992 Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 48: 763-77. PMID 1378573 DOI: 10.1016/0306-4522(92)90265-4  1
1992 Clark AS, Cotman CW. Adrenal hormone effects on hippocampal excitatory amino acid binding. Brain Research. 585: 161-8. PMID 1355001 DOI: 10.1016/0006-8993(92)91202-P  1
1992 Miller S, Cotman CW, Bridges RJ. 1-Aminocyclopentane-trans-1,3-dicarboxylic acid induces glutamine synthetase activity in cultured astrocytes. Journal of Neurochemistry. 58: 1967-70. PMID 1348527 DOI: 10.1111/j.1471-4159.1992.tb10078.x  0.01
1992 Geddes JW, Ułas J, Brunner LC, Choe W, Cotman CW. Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with alzheimer's disease: Non-N-methyl-d-aspartate receptors Neuroscience. 50: 23-34. PMID 1328933 DOI: 10.1016/0306-4522(92)90379-G  1
1992 Korotzer AR, Cotman CW. Voltage-gated currents expressed by rat microglia in culture. Glia. 6: 81-8. PMID 1328052 DOI: 10.1002/GLIA.440060202  0.01
1992 Clark AS, Magnusson KR, Cotman CW. In vitro autoradiography of hippocampal excitatory amino acid binding in aged Fischer 344 rats: relationship to performance on the Morris water maze. Behavioral Neuroscience. 106: 324-35. PMID 1317185 DOI: 10.1037//0735-7044.106.2.324  1
1992 Geddes JW, Brunner L, Cotman CW, Buzsáki G. Alterations in [3H]kainate and N-methyl-D-aspartate-sensitive L-[3H]-glutamate binding in the rat hippocampal formation following fimbria-fornix lesions. Experimental Neurology. 115: 271-81. PMID 1310474 DOI: 10.1016/0014-4886(92)90062-U  1
1992 Araujo D, Cotman C. Basic FGF in astroglial, microglial, and neuronal cultures: characterization of binding sites and modulation of release by lymphokines and trophic factors The Journal of Neuroscience. 12: 1668-1678. DOI: 10.1523/JNEUROSCI.12-05-01668.1992  0.01
1992 Gomez-Pinilla F, Lee J, Cotman C. Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbria-fornix transection The Journal of Neuroscience. 12: 345-355. DOI: 10.1523/Jneurosci.12-01-00345.1992  0.01
1991 Peterson C, Vanderklish P, Seubert P, Cotman C, Lynch G. Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors. Neuroscience Letters. 121: 239-43. PMID 2020380 DOI: 10.1016/0304-3940(91)90694-O  1
1991 Vijayan VK, Geddes JW, Anderson KJ, Chang-Chui H, Ellis WG, Cotman CW. Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation. Experimental Neurology. 112: 72-8. PMID 2013308 DOI: 10.1016/0014-4886(91)90115-S  1
1991 Patrick Kesslak J, Nalcioglu O, Cotman CW. Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in alzheimer’s disease Neurology. 41: 51-54. PMID 1985296 DOI: 10.1212/WNL.41.1.51  1
1991 Cotman CW, Geddes JW, Ulas J, Klein M. Plasticity of excitatory amino acid receptors: implications for aging and Alzheimer's disease. Progress in Brain Research. 86: 55-61. PMID 1965056 DOI: 10.1016/S0079-6123(08)63166-0  0.01
1991 Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proceedings of the National Academy of Sciences of the United States of America. 88: 10302-6. PMID 1946448 DOI: 10.1073/Pnas.88.22.10302  1
1991 Buchsbaum MS, Kesslak JP, Lynch G, Chui H, Wu J, Sicotte N, Hazlett E, Teng E, Cotman CW. Temporal and hippocampal metabolic rate during an olfactory memory task assessed by positron emission tomography in patients with dementia of the Alzheimer type and controls. Preliminary studies. Archives of General Psychiatry. 48: 840-7. PMID 1929775 DOI: 10.1001/Archpsyc.1991.01810330064010  1
1991 Copani A, Koh J, Cotman CW. β-amyloid increases neuronal susceptibility to injury by glucose deprivation Neuroreport. 2: 763-765. PMID 1793819 DOI: 10.1097/00001756-199112000-00008  1
1991 Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Research. 563: 311-4. PMID 1786545 DOI: 10.1016/0006-8993(91)91553-D  1
1991 Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. European Journal of Pharmacology. 207: 367-8. PMID 1783006 DOI: 10.1016/0922-4106(91)90014-9  1
1991 Kesslak JP, Korotzer A, Song A, Kamali K, Cotman CW. Effects of tetrahydroaminoacridine (THA) on functional recovery after sequential lesion of the entorhinal cortex Brain Research. 557: 57-63. PMID 1747769 DOI: 10.1016/0006-8993(91)90115-C  1
1991 Gómez-Pinilla F, Cummings BJ, Cotman CW. Induction of basic fibroblast growth factor in Alzheimer's disease pathology. Neuroreport. 1: 211-4. PMID 1717039 DOI: 10.1097/00001756-199011000-00009  0.04
1991 Anderson KJ, Bridges RJ, Cotman CW. Increased density of excitatory amino acid transport sites in the hippocampal formation following an entorhinal lesion Brain Research. 562: 285-290. PMID 1685344 DOI: 10.1016/0006-8993(91)90633-7  1
1991 Whittemore ER, Cotman CW. Agonists selective for phosphoinositide-coupled receptors sensitize neurons to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4). Brain Research. 555: 215-9. PMID 1681998 DOI: 10.1016/0006-8993(91)90344-U  0.01
1991 Bridges RJ, Koh Jy, Hatalski CG, Cotman CW. Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione European Journal of Pharmacology. 192: 199-200. PMID 1674918 DOI: 10.1016/0014-2999(91)90093-6  1
1991 Bridges RJ, Stanley MS, Anderson MW, Cotman CW, Chamberlin AR. Conformationally defined neurotransmitter analogues. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer. Journal of Medicinal Chemistry. 34: 717-25. PMID 1671706 DOI: 10.1021/JM00106A037  1
1991 Koh Jy, Palmer E, Lin A, Cotman CW. A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture Brain Research. 561: 338-343. PMID 1666330 DOI: 10.1016/0006-8993(91)91613-6  1
1991 Koh JY, Palmer E, Cotman CW. Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures Proceedings of the National Academy of Sciences of the United States of America. 88: 9431-9435. PMID 1658782 DOI: 10.1073/PNAS.88.21.9431  1
1991 Stevens DR, Cotman CW. Long-term potentiation of excitatory and slow inhibitory synaptic potentials in the hippocampal-septal projection of the rat. Brain Research. 558: 120-2. PMID 1657309 DOI: 10.1016/0006-8993(91)90726-C  0.01
1990 Cotman CW, Lynch GS. The neurobiology of learning and memory. Cognition. 33: 201-41. PMID 2691183 DOI: 10.1016/0010-0277(89)90010-3  0.04
1990 Cotman C, Monaghan D. Multiple excitatory amino acid receptor regulation of intracellular Ca2+. Implications for aging and Alzheimer's disease. Annals of the New York Academy of Sciences. 568: 138-48. PMID 2560895 DOI: 10.1111/j.1749-6632.1989.tb12501.x  0.12
1990 Borg J, Kesslak PJ, Cotman CW. Peripheral administration of a long-chain fatty alcohol promotes septal cholinergic neurons survival after fimbria-fornix transection. Brain Research. 518: 295-8. PMID 2390721 DOI: 10.1016/0006-8993(90)90985-K  0.01
1990 Peterson C, Cotman CW. Decreased survival of hippocampal neurons in medium conditioned by fibroblasts from aged and Alzheimer donors. Brain Research. 515: 39-44. PMID 2357575 DOI: 10.1016/0006-8993(90)90573-T  0.01
1990 Russell MJ, Vijayan VK, Gibbs RB, Geddes JW, Jacobson CH, Cotman CW. Long-term survival of neural transplants to senescence in rats. Experimental Neurology. 108: 105-8. PMID 2335191 DOI: 10.1016/0014-4886(90)90015-K  1
1990 Geddes JW, Wong J, Choi BH, Kim RC, Cotman CW, Miller FD. Increased expression of the embryonic form of a developmentally regulated mRNA in Alzheimer's disease. Neuroscience Letters. 109: 54-61. PMID 2314641 DOI: 10.1016/0304-3940(90)90537-J  1
1990 Seubert P, Peterson C, Vanderklish P, Cotman C, Lynch G. Increased spectrin proteolysis in the brindled mouse brain. Neuroscience Letters. 108: 303-8. PMID 2304649 DOI: 10.1016/0304-3940(90)90658-V  1
1990 Koh Jy, Yang LL, Cotman CW. β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage Brain Research. 533: 315-320. PMID 2289145 DOI: 10.1016/0006-8993(90)91355-K  1
1990 Cotman CW, Geddes JW, Kahle JS. Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms? Progress in Brain Research. 83: 427-34. PMID 2203106 DOI: 10.1016/S0079-6123(08)61266-2  1
1990 Whitson JS, Glabe CG, Shintani E, Abcar A, Cotman CW. Beta-amyloid protein promotes neuritic branching in hippocampal cultures. Neuroscience Letters. 110: 319-24. PMID 2183090 DOI: 10.1016/0304-3940(90)90867-9  1
1990 Ułas J, Monaghan DT, Cotman CW. Kainate receptors in the rat hippocampus: A distribution and time course of changes in response to unilateral lesions of the entorhinal cortex Journal of Neuroscience. 10: 2352-2362. PMID 2165522 DOI: 10.1523/Jneurosci.10-07-02352.1990  1
1990 Geddes JW, Cahan LD, Cooper SM, Kim RC, Choi BH, Cotman CW. Altered distribution of excitatory amino acid receptors in temporal lobe epilepsy. Experimental Neurology. 108: 214-20. PMID 2161774 DOI: 10.1016/0014-4886(90)90125-C  1
1990 Ułas J, Monaghan DT, Cotman CW. Plastic response of hippocampal excitatory amino acid receptors to deafferentation and reinnervation Neuroscience. 34: 9-17. PMID 2158009 DOI: 10.1016/0306-4522(90)90300-S  1
1990 Baudry M, Monaghan D, Cotman C, Altar CA. Regional distribution of alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding sites in rat brain: effect of chemical modification of SH- groups in tissue sections. Journal of Neurochemistry. 54: 1682-8. PMID 2157815 DOI: 10.1111/j.1471-4159.1990.tb01222.x  0.04
1990 Palmer E, Nangel-Taylor K, Krause JD, Roxas A, Cotman CW. Changes in excitatory amino acid modulation of phosphoinositide metabolism during development. Brain Research. Developmental Brain Research. 51: 132-4. PMID 2153480 DOI: 10.1016/0165-3806(90)90266-2  1
1990 Geddes JW, Wilson MC, Miller FD, Cotman CW. Molecular markers of reactive plasticity. Advances in Experimental Medicine and Biology. 268: 425-32. PMID 2075860 DOI: 10.1007/978-1-4684-5769-8_47  1
1990 Anderson KJ, Monaghan DT, Bridges RJ, Tavoularis AL, Cotman CW. Autoradiographic characterization of putative excitatory amino acid transport sites Neuroscience. 38: 311-322. PMID 1979852 DOI: 10.1016/0306-4522(90)90030-8  1
1990 Peterson C, Giguere JF, Cotman CW, Butterworth RF. Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis. Journal of Neurochemistry. 55: 386-90. PMID 1973453 DOI: 10.1111/j.1471-4159.1990.tb04149.x  1
1990 Cahan LD, Geddes JW, Choi BH, Cotman C. Excitotoxic amino acid receptors in human complex partial epilepsy. Stereotactic and Functional Neurosurgery. 54: 21-24. PMID 1964242 DOI: 10.1159/000100185  1
1990 Geddes JW, Hess EJ, Hart RA, Kesslak JP, Cotman CW, Wilson MC. Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker. Neuroscience. 38: 515-25. PMID 1702194 DOI: 10.1016/0306-4522(90)90047-8  1
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