| Year |
Citation |
Score |
| 2002 |
Trofimova-Griffin ME, Juchau MR. Developmental expression of cytochrome CYP26B1 (P450RAI-2) in human cephalic tissues. Brain Research. Developmental Brain Research. 136: 175-8. PMID 12101034 DOI: 10.1016/S0165-3806(02)00305-X |
0.311 |
|
| 2000 |
Trofimova-Griffin ME, Brzezinski MR, Juchau MR. Patterns of CYP26 expression in human prenatal cephalic and hepatic tissues indicate an important role during early brain development. Brain Research. Developmental Brain Research. 120: 7-16. PMID 10727725 DOI: 10.1016/S0165-3806(99)00185-6 |
0.352 |
|
| 1998 |
Trofimova-Griffin ME, Juchau MR. Expression of cytochrome P450RAI (CYP26) in human fetal hepatic and cephalic tissues. Biochemical and Biophysical Research Communications. 252: 487-91. PMID 9826557 DOI: 10.1006/Bbrc.1998.9659 |
0.326 |
|
| 1998 |
Chen H, Juchau MR. Recombinant human glutathione S-transferases catalyse enzymic isomerization of 13-cis-retinoic acid to all-trans-retinoic acid in vitro. The Biochemical Journal. 336: 223-6. PMID 9806904 DOI: 10.1042/Bj3360223 |
0.314 |
|
| 1998 |
Juchau MR, Boutelet-Bochan H, Huang Y. Cytochrome-P450-dependent biotransformation of xenobiotics in human and rodent embryonic tissues. Drug Metabolism Reviews. 30: 541-68. PMID 9710705 DOI: 10.3109/03602539808996324 |
0.302 |
|
| 1998 |
Chen H, Juchau MR. Inhibition of embryonic retinoic acid synthesis by aldehydes of lipid peroxidation and prevention of inhibition by reduced glutathione and glutathione S-transferases. Free Radical Biology & Medicine. 24: 408-17. PMID 9438553 DOI: 10.1016/S0891-5849(97)00272-4 |
0.302 |
|
| 1997 |
Boutelet-Bochan H, Huang Y, Juchau MR. Expression of CYP2E1 during embryogenesis and fetogenesis in human cephalic tissues: implications for the fetal alcohol syndrome. Biochemical and Biophysical Research Communications. 238: 443-7. PMID 9299528 DOI: 10.1006/Bbrc.1997.7296 |
0.345 |
|
| 1996 |
Lee QP, Park HW, Thayer J, Mirkes PE, Juchau MR. Apoptosis induced in cultured rat embryos by intra-amniotically microinjected sodium nitroprusside. Teratology. 53: 21-30. PMID 8928084 DOI: 10.1002/(Sici)1096-9926(199601)53:1<21::Aid-Tera3>3.0.Co;2-C |
0.302 |
|
| 1996 |
Chen H, Yang HY, Namkung MJ, Juchau MR. Interactive dysmorphogenic effects of all-trans-retinol and ethanol on cultured whole rat embryos during organogenesis. Teratology. 54: 12-9. PMID 8916365 DOI: 10.1002/(Sici)1096-9926(199607)54:1<12::Aid-Tera2>3.0.Co;2-5 |
0.303 |
|
| 1996 |
Miller MS, Juchau MR, Guengerich FP, Nebert DW, Raucy JL. Drug Metabolic Enzymes in Developmental Toxicology Toxicological Sciences. 34: 165-175. DOI: 10.1093/Toxsci/34.2.165 |
0.356 |
|
| 1995 |
Yang HY, Namkung MJ, Juchau MR. Expression of functional cytochrome P4501A1 in human embryonic hepatic tissues during organogenesis. Biochemical Pharmacology. 49: 717-26. PMID 7887987 DOI: 10.1016/0006-2952(94)00493-6 |
0.367 |
|
| 1994 |
Chapman DE, Namkung MJ, Juchau MR. Benzene and benzene metabolites as embryotoxic agents: effects on cultured rat embryos. Toxicology and Applied Pharmacology. 128: 129-37. PMID 8079346 DOI: 10.1006/Taap.1994.1190 |
0.41 |
|
| 1994 |
Chapman DE, Yang HY, Watters JJ, Juchau MR. Induction in vitro and complete coding region sequence of cytochrome P4501A1 cDNA from cultured whole rat conceptuses during early organogenesis. Biochemical Pharmacology. 48: 1807-14. PMID 7980650 DOI: 10.1016/0006-2952(94)90467-7 |
0.378 |
|
| 1994 |
Yang HY, Lee QP, Rettie AE, Juchau MR. Functional cytochrome P4503A isoforms in human embryonic tissues: expression during organogenesis. Molecular Pharmacology. 46: 922-8. PMID 7969081 |
0.528 |
|
| 1994 |
Lee QP, Juchau MR. Dysmorphogenic effects of nitric oxide (NO) and NO-synthase inhibition: studies with intra-amniotic injections of sodium nitroprusside and NG-monomethyl-L-arginine. Teratology. 49: 452-64. PMID 7538231 DOI: 10.1002/Tera.1420490605 |
0.321 |
|
| 1993 |
Kraft JC, Shepard T, Juchau MR. Tissue levels of retinoids in human embryos/fetuses. Reproductive Toxicology (Elmsford, N.Y.). 7: 11-5. PMID 8448410 DOI: 10.1016/0890-6238(93)90004-Q |
0.346 |
|
| 1992 |
Lee QP, Juchau MR. Mechanisms of glucagon-induced increases in rates of cytochrome P450-dependent pentoxyphenoxazone O-depentylation in cultured rat conceptuses. Reproductive Toxicology (Elmsford, N.Y.). 6: 525-31. PMID 1337707 DOI: 10.1016/0890-6238(92)90037-T |
0.36 |
|
| 1991 |
Yang HY, Zelus BD, Juchau MR. Organogenesis-stage cytochrome P450 isoforms: utilization of PCR for detection of CYP1A1 mRNA in rat conceptal tissues. Biochemical and Biophysical Research Communications. 178: 236-41. PMID 2069563 DOI: 10.1016/0006-291X(91)91804-L |
0.339 |
|
| 1991 |
Seegmiller RE, Harris C, Luchtel DL, Juchau MR. Morphological differences elicited by two weak acids, retinoic and valproic, in rat embryos grown in vitro. Teratology. 43: 133-50. PMID 2014479 DOI: 10.1002/Tera.1420430206 |
0.347 |
|
| 1991 |
Fantel AG, Person RE, Burroughs-Gleim C, Shepard TH, Juchau MR, Mackler B. Asymmetric development of mitochondrial activity in rat embryos as a determinant of the defect patterns induced by exposure to hypoxia, hyperoxia, and redox cyclers in vitro. Teratology. 44: 355-62. PMID 1948769 DOI: 10.1002/Tera.1420440311 |
0.318 |
|
| 1991 |
Lee QP, Juchau MR, Kraft JC. Microinjection of cultured rat embryos: studies with retinol, 13-cis- and all-trans-retinoic acid. Teratology. 44: 313-23. PMID 1948766 DOI: 10.1002/Tera.1420440308 |
0.316 |
|
| 1991 |
Juchau MR, Harris C, Stark KL, Lee QP, Yang HY, Namkung MJ, Fantel AG. Cytochrome P450-dependent bioactivation of prodysmorphogens in cultured conceptuses. Reproductive Toxicology (Elmsford, N.Y.). 5: 259-63. PMID 1807561 DOI: 10.1016/0890-6238(91)90060-S |
0.422 |
|
| 1991 |
Lee QH, Fantel AG, Juchau MR. Human embryonic cytochrome P450S: phenoxazone ethers as probes for expression of functional isoforms during organogenesis. Biochemical Pharmacology. 42: 2377-85. PMID 1764121 DOI: 10.1016/0006-2952(91)90244-Y |
0.333 |
|
| 1991 |
Bechter R, Terlouw GD, Lee QP, Juchau MR. Effects of QA 208-199 and its metabolite 209-668 on embryonic development in vitro after microinjection into the exocoelomic space or into the amniotic cavity of cultured rat conceptuses. Teratogenesis, Carcinogenesis, and Mutagenesis. 11: 185-94. PMID 1685806 DOI: 10.1002/Tcm.1770110403 |
0.358 |
|
| 1990 |
Juchau MR. Substrate specificities and functions of the P450 cytochromes. Life Sciences. 47: 2385-94. PMID 2263165 DOI: 10.1016/0024-3205(90)90482-7 |
0.341 |
|
| 1989 |
Beyer BK, Stark KL, Fantel AG, Juchau MR. Biotransformation, estrogenicity, and steroid structure as determinants of dysmorphogenic and generalized embryotoxic effects of steroidal and nonsteroidal estrogens. Toxicology and Applied Pharmacology. 98: 113-27. PMID 2929019 DOI: 10.1016/0041-008X(89)90139-7 |
0.309 |
|
| 1989 |
Stark KL, Juchau MR. Microinjection of cultured rat embryos: a new technique for studies in chemical dysmorphogenesis. Toxicology and Applied Pharmacology. 100: 411-6. PMID 2781566 DOI: 10.1016/0041-008X(89)90289-5 |
0.32 |
|
| 1989 |
Stark KL, Harris C, Juchau MR. Influence of electrophilic character and glutathione depletion on chemical dysmorphogenesis in cultured rat embryos. Biochemical Pharmacology. 38: 2685-92. PMID 2764988 DOI: 10.1016/0006-2952(89)90555-8 |
0.36 |
|
| 1989 |
Fantel AG, Juchau MR, Tracy JW, Burroughs CJ, Person RE. Studies of mechanisms of niridazole-elicited embryotoxicity: evidence against a major role for covalent binding. Teratology. 39: 63-74. PMID 2718141 DOI: 10.1002/Tera.1420390108 |
0.404 |
|
| 1989 |
Yang HY, Namkung MJ, Juchau MR. Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis. Biochemical Pharmacology. 38: 4027-36. PMID 2688652 DOI: 10.1016/0006-2952(89)90683-7 |
0.383 |
|
| 1989 |
Hulla JE, Juchau MR. Developmental aspects of P450IIIA: prenatal activity and inducibility. Drug Metabolism Reviews. 20: 765-79. PMID 2680406 DOI: 10.3109/03602538909103577 |
0.354 |
|
| 1989 |
Stark KL, Harris C, Juchau MR. Modulation of the embryotoxicity and cytotoxicity elicited by 7-hydroxy-2-acetylaminofluorene and acetaminophen via deacetylation. Toxicology and Applied Pharmacology. 97: 548-60. PMID 2609350 DOI: 10.1016/0041-008X(89)90260-3 |
0.365 |
|
| 1989 |
Harris C, Stark KL, Luchtel DL, Juchau MR. Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens. Toxicology and Applied Pharmacology. 101: 432-46. PMID 2603160 DOI: 10.1016/0041-008X(89)90192-0 |
0.396 |
|
| 1989 |
Fantel AG, Juchau MR, Burroughs CJ, Person RE. Studies of embryotoxic mechanisms of niridazole: evidence that oxygen depletion plays a role in dysmorphogenicity. Teratology. 39: 243-51. PMID 2543096 DOI: 10.1002/Tera.1420390306 |
0.338 |
|
| 1988 |
Beyer BK, Juchau MR. Contrasting effects of estradiol-17β and 17α-ethinyl estradiol-17β on cultured whole embryos Journal of Steroid Biochemistry. 29: 629-634. PMID 3386229 DOI: 10.1016/0022-4731(88)90162-8 |
0.312 |
|
| 1988 |
Fantel AG, Person RE, Tracy JW, Juchau MR. Niridazole metabolism by rat embryos in vitro. Teratology. 37: 213-21. PMID 3368875 DOI: 10.1002/Tera.1420370306 |
0.368 |
|
| 1988 |
Harris C, Stark KL, Juchau MR. Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro. Teratology. 37: 577-90. PMID 3135633 DOI: 10.1002/Tera.1420370607 |
0.35 |
|
| 1987 |
Harris C, Namkung MJ, Juchau MR. Regulation of intracellular glutathione in rat embryos and visceral yolk sacs and its effect on 2-nitrosofluorene-induced malformations in the whole embryo culture system. Toxicology and Applied Pharmacology. 88: 141-52. PMID 3564029 DOI: 10.1016/0041-008X(87)90278-X |
0.337 |
|
| 1987 |
Beyer BK, Greenaway JC, Fantel AG, Juchau MR. Embryotoxicity induced by diethylstilbestrol in vitro Journal of Biochemical Toxicology. 2: 77-92. PMID 3508481 DOI: 10.1002/Jbt.2570020202 |
0.375 |
|
| 1987 |
Beyer BK, Juchau MR. Conversion of estradiol-17β to reactive embryotoxic intermediates by cytochrome P-450-dependent bioactivating systems Biochemical and Biophysical Research Communications. 145: 402-407. PMID 3036127 DOI: 10.1016/0006-291X(87)91336-2 |
0.359 |
|
| 1987 |
Stark KL, Harris C, Juchau MR. Embryotoxicity elicited by inhibition of gamma-glutamyltransferase by Acivicin and transferase antibodies in cultured rat embryos. Toxicology and Applied Pharmacology. 89: 88-96. PMID 2884755 DOI: 10.1016/0041-008X(87)90179-7 |
0.369 |
|
| 1986 |
Greenaway JC, Fantel AG, Juchau MR. On the capacity of nitroheterocyclic compounds to elicit an unusual axial asymmetry in cultured rat embryos. Toxicology and Applied Pharmacology. 82: 307-15. PMID 3945955 DOI: 10.1016/0041-008X(86)90206-1 |
0.356 |
|
| 1986 |
Juchau MR, Fantel AG, Harris C, Beyer BK. The potential role of redox cycling as a mechanism for chemical teratogenesis Environmental Health Perspectives. 131-136. PMID 3830098 DOI: 10.1289/Ehp.8670131 |
0.342 |
|
| 1986 |
Harris C, Fantel AG, Juchau MR. Differential glutathione depletion by L-buthionine-S,R-sulfoximine in rat embryo versus visceral yolk sac in vivo and in vitro. Biochemical Pharmacology. 35: 4437-41. PMID 3790163 DOI: 10.1016/0006-2952(86)90760-4 |
0.322 |
|
| 1986 |
Faustman-Watts EM, Namkung MJ, Juchau MR. Modulation of the embryotoxicity in vitro of reactive metabolites of 2-acetylaminofluorene by reduced glutathione and ascorbate and via sulfation. Toxicology and Applied Pharmacology. 86: 400-10. PMID 3787633 DOI: 10.1016/0041-008X(86)90367-4 |
0.347 |
|
| 1986 |
Fantel AG, Greenaway JC, Walker E, Juchau MR. The toxicity of niridazole in rat embryos in vitro. Teratology. 33: 105-12. PMID 3738802 DOI: 10.1002/Tera.1420330113 |
0.406 |
|
| 1986 |
Dean PA, Rettie AE, Turnblom SM, Namkung MJ, Juchau MR. Cytosolic activation of hematin-dependent microsomal monooxygenase activity in the lung. Chemico-Biological Interactions. 58: 79-94. PMID 3708723 DOI: 10.1016/S0009-2797(86)80088-6 |
0.592 |
|
| 1986 |
Faustman-Watts EM, Giachelli CM, Juchau MR. Carbon monoxide inhibits monooxygenation by the conceptus and embryotoxic effects of proteratogens in vitro Toxicology and Applied Pharmacology. 83: 590-595. PMID 3705078 DOI: 10.1016/0041-008X(86)90242-5 |
0.366 |
|
| 1986 |
Rettie AE, Rettenmeier AW, Beyer BK, Baillie TA, Juchau MR. Valproate hydroxylation by human fetal tissues and embryotoxicity of metabolites. Clinical Pharmacology and Therapeutics. 40: 172-7. PMID 3089669 DOI: 10.1038/Clpt.1986.160 |
0.59 |
|
| 1985 |
Juchau MR, Bark DH, Shewey LM, Greenaway JC. Generation of reactive dysmorphogenic intermediates by rat embryos in culture: effects of cytochrome P-450 inducers. Toxicology and Applied Pharmacology. 81: 533-44. PMID 4082200 DOI: 10.1016/0041-008X(85)90424-7 |
0.431 |
|
| 1985 |
Greenaway JC, Mirkes PE, Walker EA, Juchau MR, Shepard TH, Fantel AG. The effect of oxygen concentration on the teratogenicity of salicylate, niridazole, cyclophosphamide, and phosphoramide mustard in rat embryos in vitro. Teratology. 32: 287-95. PMID 4049287 DOI: 10.1002/Tera.1420320217 |
0.327 |
|
| 1985 |
Faustman-Watts EM, Namkung MJ, Greenaway JC, Juchau MR. Analysis of metabolites of 2-acetylaminofluorene generated in an embryo culture system. Relationship of biotransformation to teratogenicity in vitro. Biochemical Pharmacology. 34: 2953-9. PMID 4026879 DOI: 10.1016/0006-2952(85)90021-8 |
0.364 |
|
| 1985 |
Fantel AG, Greenaway JC, Juchau MR. The embryotoxicity of adriamycin in rat embryos in vitro. Toxicology and Applied Pharmacology. 80: 155-65. PMID 4024103 DOI: 10.1016/0041-008X(85)90110-3 |
0.399 |
|
| 1985 |
Juchau MR, Giachelli CM, Fantel AG, Greenaway JC, Shepard TH, Faustman-Watts EM. Effects of 3-methylcholanthrene and phenobarbital on the capacity of embryos to bioactivate teratogens during organogenesis Toxicology and Applied Pharmacology. 80: 137-146. PMID 4024101 DOI: 10.1016/0041-008X(85)90108-5 |
0.382 |
|
| 1985 |
Namkung MJ, Porubek DJ, Nelson SD, Juchau MR. Regulation of aromatic oxidation of estradiol-17β in maternal hepatic, fetal hepatic and placental tissues: Comparative effects of a series of inducing agents Journal of Steroid Biochemistry. 22: 563-567. PMID 3999749 DOI: 10.1016/0022-4731(85)90179-7 |
0.4 |
|
| 1985 |
Rettie AE, Heimark L, Mayer RT, Burke MD, Trager WF, Juchau MR. Stereoselective and regioselective hydroxylation of warfarin and selective O-dealkylation of phenoxazone ethers in human placenta. Biochemical and Biophysical Research Communications. 126: 1013-21. PMID 3977899 DOI: 10.1016/0006-291X(85)90286-4 |
0.656 |
|
| 1984 |
Greenaway JC, Bark DH, Juchau MR. Embryotoxic effects of salicylates: role of biotransformation. Toxicology and Applied Pharmacology. 74: 141-9. PMID 6729819 DOI: 10.1016/0041-008X(84)90280-1 |
0.37 |
|
| 1984 |
Faustman-Watts EM, Greenaway JC, Namkung MJ, Fantel AG, Juchau MR. Teratogenicity in vitro of two deacetylated metabolites of N-hydroxy-2-acetylaminofluorene. Toxicology and Applied Pharmacology. 76: 161-71. PMID 6484986 DOI: 10.1016/0041-008X(84)90039-5 |
0.347 |
|
| 1984 |
Faustman-Watts EM, Yang HY, Namkung MJ, Greenaway JC, Fantel AG, Juchau MR. Mutagenic, cytotoxic, and teratogenic effects of 2-acetylaminofluorene and reactive metabolites in vitro. Teratogenesis, Carcinogenesis, and Mutagenesis. 4: 273-83. PMID 6147026 DOI: 10.1002/Tcm.1770040303 |
0.353 |
|
| 1983 |
Faustman-Watts E, Greenaway JC, Namkung MJ, Fantel AG, Juchau MR. Teratogenicity in vitro of 2-acetylaminofluorene: role of biotransformation in the rat. Teratology. 27: 19-28. PMID 6845215 DOI: 10.1002/Tera.1420270105 |
0.376 |
|
| 1983 |
Majesky MW, Yang HYL, Benditt EP, Juchau MR. Carcinogenesis and atherogenesis: Differences in monooxygenase inducibility and bioactivation of benzo[a]pyrene in aortic and hepatic tissues of atherosclerosis-susceptible versus resistant pigeons Carcinogenesis. 4: 647-652. PMID 6305525 DOI: 10.1093/Carcin/4.6.647 |
0.338 |
|
| 1982 |
Omiecinski CJ, Namkung MJ, Juchau MR. Substrate and position specificity of hematin-activated monooxygenation reactions. Biochemical Pharmacology. 30: 2837-45. PMID 7317078 DOI: 10.1016/0006-2952(81)90423-8 |
0.357 |
|
| 1982 |
Greenaway JC, Shepard TH, Fantel AG, Juchau MR. Sodium salicylate teratogenicity in vitro. Teratology. 26: 167-71. PMID 7157193 DOI: 10.1002/Tera.1420260209 |
0.339 |
|
| 1982 |
Greenaway JC, Fantel AG, Shepard TH, Juchau MR. The in vitro teratogenicity of cyclophosphamide in rat embryos. Teratology. 25: 335-43. PMID 7112435 DOI: 10.1002/Tera.1420250310 |
0.371 |
|
| 1981 |
Fantel AG, Greenaway JC, Shepard TH, Juchau MR, Selleck SB. The teratogenicity of cytochalasin D and its inhibition by drug metabolism. Teratology. 23: 223-31. PMID 7268639 DOI: 10.1002/Tera.1420230207 |
0.338 |
|
| 1980 |
Namkung MJ, Juchau MR. On the capacity of human placental enzymes to catalyze the formation of diols from benzo[a]pyrene. Toxicology and Applied Pharmacology. 55: 253-9. PMID 7423515 DOI: 10.1016/0041-008X(80)90087-3 |
0.361 |
|
| 1980 |
Chao ST, Juchau MR. Interactions of endogenous and exogenous estrogenic compounds with human placental microsomal cytochrome P-450 (P-450hpm). Journal of Steroid Biochemistry. 13: 127-33. PMID 7382489 DOI: 10.1016/0022-4731(80)90183-1 |
0.333 |
|
| 1980 |
DiGiovanni J, Slaga TJ, Berry DL, Juchau MR. Inhibitory effects of environmental chemicals on polycyclic aromatic hydrocarbon carcinogenesis Carcinogenesis; a Comprehensive Survey. 5: 145-168. PMID 6992995 |
0.403 |
|
| 1980 |
DiGiovanni J, Juchau MR. Biotransformation and bioactivation of 7, 12-dimethylbenz[a]anthracene (7, 12-DMBA). Drug Metabolism Reviews. 11: 61-101. PMID 6775921 DOI: 10.3109/03602538008994022 |
0.527 |
|
| 1980 |
Bond JA, Yang HYL, Majesky MW, Benditt EP, Juchau MR. Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in chicken aortas: Monooxygenation, bioactivation to mutagens, and covalent binding to DNA in vitro Toxicology and Applied Pharmacology. 52: 323-335. PMID 6244684 DOI: 10.1016/0041-008X(80)90119-2 |
0.34 |
|
| 1980 |
Omieoinski CJ, Juchau MR. AUGMFNTATION BY HEMATIN OF RATES OF BENZO[a]PYRENE HYDROXYLATION: THE POSSIBLE INVOLVEMENT OF CYTOCHROME P-450 Microsomes, Drug Oxidations and Chemical Carcinogenesis. 969-972. DOI: 10.1016/B978-0-12-187702-6.50075-X |
0.347 |
|
| 1979 |
Fantel AG, Greenaway JC, Juchau MR, Shepard TH. Teratogenic bioactivation of cyclophosphamide in vitro. Life Sciences. 25: 67-72. PMID 481123 DOI: 10.1016/0024-3205(79)90491-0 |
0.355 |
|
| 1979 |
DiGiovanni J, Berry DL, Slaga TJ, Jones AH, Juchau MR. Effects of pretreatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin on the capacity of hepatic and extrahepatic mouse tissues to convert procarcinogens to mutagens for Salmonella typhimurium auxotrophs. Toxicology and Applied Pharmacology. 50: 229-39. PMID 388724 DOI: 10.1016/0041-008X(79)90148-0 |
0.548 |
|
| 1979 |
Juchau MR, DiGiovanni J, Namkung MJ, Jones AH. A comparison of the capacity of fetal and adult liver, lung, and brain to convert polycyclic aromatic hydrocarbons to mutagenic and cytotoxic metabolites in mice and rats. Toxicology and Applied Pharmacology. 49: 171-8. PMID 382440 DOI: 10.1016/0041-008X(79)90288-6 |
0.548 |
|
| 1979 |
Berry DL, Slaga TJ, DiGiovanni J, Juchau MR. Studies with chlorinated dibenzo-p-dioxins, polybrominated biphenyls, and polychlorinated biphenyls in a two-stage system of mouse skin tumorigenesis: potent anticarcinogenic effects Annals of the New York Academy of Sciences. 320: 405-414. PMID 222192 DOI: 10.1111/J.1749-6632.1979.Tb56621.X |
0.546 |
|
| 1979 |
Bond JA, Kocan RM, Benditt EP, Juchau MR. Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human fetal aortic smooth muscle cells. Life Sciences. 25: 425-30. PMID 113639 DOI: 10.1016/0024-3205(79)90574-5 |
0.33 |
|
| 1979 |
DiGiovanni J, Romson JR, Linville D, Juchau MR, Slaga TJ. Covalent binding of polycyclic aromatic hydrocarbons to adenine correlates with tumorigenesis in mouse skin Cancer Letters. 7: 39-43. PMID 110439 DOI: 10.1016/S0304-3835(79)80074-9 |
0.475 |
|
| 1979 |
DiGiovanni J, Berry DL, Juchau MR, Slaga TJ. 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Potent anticarcinogenic activity in CD-1 mice Biochemical and Biophysical Research Communications. 86: 577-584. PMID 106852 DOI: 10.1016/0006-291X(79)91752-2 |
0.527 |
|
| 1979 |
Bond JA, Omiecinski CJ, Juchau MR. Kinetics, activation, and induction of aortic mono-oxygenases--biotransformation of benzo[a]pyrene. Biochemical Pharmacology. 28: 305-11. PMID 34402 DOI: 10.1016/0006-2952(79)90520-3 |
0.344 |
|
| 1978 |
Omiecinski CJ, Bond JA, Juchau MR. Stimulation by hematin of monooxygenase activity in extra-hepatic tissues from rats, rabbits and chickens. Biochemical and Biophysical Research Communications. 83: 1004-11. PMID 708418 DOI: 10.1016/0006-291X(78)91495-X |
0.413 |
|
| 1978 |
Hodgson E, Juchau MR. Ligand binding to human placental cytochrome P-450: interaction of steroids and heme-binding ligands. Journal of Steroid Biochemistry. 8: 669-75. PMID 592792 DOI: 10.1016/0022-4731(77)90295-3 |
0.304 |
|
| 1978 |
Berry DL, Zachariah PK, Slaga TJ, Juchau MR. Analysis of the biotransformation of benzo [a] pyrene in human fetal and placental tissues with high-pressure liquid chromatography. European Journal of Cancer. 13: 667-75. PMID 413719 DOI: 10.1016/0014-2964(77)90052-4 |
0.393 |
|
| 1978 |
Berry DL, DiGiovanni J, Juchau MR, Bracken WM, Gleason GL, Slaga TJ. Lack of tumor-promoting ability of certain environmental chemicals in a two-stage mouse skin tumorigenesis assay Research Communications in Chemical Pathology and Pharmacology. 20: 101-108. PMID 208126 |
0.424 |
|
| 1978 |
Juchau MR, Namkung MJ, Jones AH, DiGiovanni J. Biotransformation and bioactivation of 7,12-dimethylbenz[a]anthracene in human fetal and placental tissues. Analyses of HPLC profiles and studies with Salmonella typhimurium. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 273-81. PMID 26548 |
0.458 |
|
| 1977 |
Berry DL, Bracken WR, Slaga TJ, Wilson NM, Butty SG, Juchau MR. Benzo(a)pyrene metabolism in mouse epidermis. Analysis by high pressure liquid chromatography and DNA binding. Chemico-Biological Interactions. 18: 129-42. PMID 890843 DOI: 10.1016/0009-2797(77)90001-1 |
0.319 |
|
| 1977 |
Zachariah PK, Juchau MR. Inhibition of human placental mixed-function oxidations with carbon monoxide: reversal with monochromatic light. Journal of Steroid Biochemistry. 8: 221-8. PMID 859324 DOI: 10.1016/0022-4731(77)90055-3 |
0.314 |
|
| 1977 |
DiGiovanni J, Viaje A, Berry DL, Slaga TJ, Juchau MR. Tumor-initiating ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Arochlor 1254 in the two-stage system of mouse skin carcinogenesis. Bulletin of Environmental Contamination and Toxicology. 18: 552-7. PMID 412534 DOI: 10.1007/Bf01684000 |
0.485 |
|
| 1977 |
Slaga TJ, Thompson S, Berry DL, Digiovanni J, Juchau MR, Viaje A. The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation. Chemico-Biological Interactions. 17: 297-312. PMID 407010 DOI: 10.1016/0009-2797(77)90093-X |
0.505 |
|
| 1977 |
Berry DL, Slaga TJ, Viaje A, Wilson NM, DiGiovanni J, Juchau MR, Selkirk JK. Effect of trichloropropene oxide on the ability of polyaromatic hydrocarbons and their "K-region" oxides to initiate skin tumors in mice and to bind to DNA in vitro. Journal of the National Cancer Institute. 58: 1051-5. PMID 403293 DOI: 10.1093/Jnci/58.4.1051 |
0.503 |
|
| 1977 |
Jones AH, Fantel AG, Kocan RA, Juchau MR. Bioactivation of procarcinogens to mutagens in human fetal and placental tissues. Life Sciences. 21: 1831-5. PMID 342853 DOI: 10.1016/0024-3205(77)90165-5 |
0.361 |
|
| 1977 |
Zachariah PK, Slaga TJ, Berry DL, Bracken WM, Buty SG, Martinsen CM, Juchau MR. The ability of enteric bacteria to catalyze the covalent binding of bile acids and cholesterol to DNA and their in ability to metabolize benzo(a)pyrene to a binding product and to known metabolites. Cancer Letters. 3: 99-105. PMID 19150 DOI: 10.1016/S0304-3835(77)94577-3 |
0.325 |
|
| 1977 |
DiGiovanni J, Slaga TJ, Berry DL, Juchau MR. Metabolism of 7,12-dimethylbenz[a]anthracene in mouse skin homogenates analyzed with high-pressure liquid chromatography. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 5: 295-301. PMID 17529 |
0.51 |
|
| 1976 |
Lee QP, Zachariah PK, Juchau MR. Differential inhibition of androst-4-en-3,17-dione aromatization by carbon monoxide in the presence of estr-4-en-3,17-dione. Steroids. 26: 571-8. PMID 1209686 DOI: 10.1016/0039-128X(75)90051-3 |
0.306 |
|
| 1976 |
Berry DL, Zachariah PK, Namkung MJ, Juchau MR. Transplacental induction of carcinogen-hydroxylating systems with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology and Applied Pharmacology. 36: 569-84. PMID 941154 DOI: 10.1016/0041-008X(76)90236-2 |
0.371 |
|
| 1976 |
Juchau MR, Bond JA, Benditt EP. Aryl 4-monooxygenase and cytochrome P-450 in the aorta: possible role in atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 73: 3723-5. PMID 824648 DOI: 10.1073/Pnas.73.10.3723 |
0.361 |
|
| 1976 |
Zachariah PK, Lee QP, Symms KG, Juchau MR. Further studies on the properties of human placental microsomal cytochrome P-450. Biochemical Pharmacology. 25: 793-800. PMID 7272 DOI: 10.1016/0006-2952(76)90149-0 |
0.354 |
|
| 1976 |
Pedersen MG, Hershberger WK, Zachariah PK, Juchau MR. Hepatic Biotransformation of Environmental Xenobiotics in Six Strains of Rainbow Trout (Salmo gairdneri) Journal of the Fisheries Research Board of Canada. 33: 666-675. DOI: 10.1139/F76-082 |
0.338 |
|
| 1975 |
Pedersen MG, Hershberger WK, Juchau MR. Metabolism of 3,4-benzpyrene in rainbow trout (Salmo gairdneri). Bulletin of Environmental Contamination and Toxicology. 12: 481-6. PMID 4154789 DOI: 10.1007/Bf01684986 |
0.329 |
|
| 1975 |
Zachariah K, Juchau MR. Interactions of steroids with human placental cytochrome P-450 in the presence of carbon monoxide. Life Sciences. 16: 1689-92. PMID 1142995 DOI: 10.1016/0024-3205(75)90052-1 |
0.322 |
|
| 1975 |
Juchau MR, Zachariah PK. Displacement of carbon monoxide from placental cytochrome P-450 by steroids: antagonistic effects of androstenedione and 19-norandrostenedione. Biochemical and Biophysical Research Communications. 65: 1026-32. PMID 239710 DOI: 10.1016/S0006-291X(75)80488-8 |
0.34 |
|
| 1975 |
Juchau MR, Zachariah PK. Comparative studies on the oxidation and reduction of drug substrates in human placental versus rat hepatic microsomes. Biochemical Pharmacology. 24: 227-33. PMID 234233 DOI: 10.1016/0006-2952(75)90281-6 |
0.404 |
|
| 1974 |
Juchau MR, Smuckler EA. Subcellular localization of human placental aryl hydrocarbon hydroxylase. Toxicology and Applied Pharmacology. 26: 163-79. PMID 4356362 DOI: 10.1016/0041-008X(73)90250-0 |
0.304 |
|
| 1973 |
Juchau MR, Pedersen MG. Drug biotransformation reactions in the human fetal adrenal gland. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 12: 193-204. PMID 4633079 DOI: 10.1016/0024-3205(73)90347-0 |
0.407 |
|
| 1973 |
Juchau MR, Pedersen MG, Symms KG. Hydroxylation of 3,4-benzpyrene in human fetal tissue homogenates. Biochemical Pharmacology. 21: 2269-72. PMID 4630402 DOI: 10.1016/0006-2952(72)90044-5 |
0.306 |
|
| 1973 |
Juchau MR, Symms KG. Aniline hydroxylation in the human placenta--mechanistic aspects. Biochemical Pharmacology. 21: 2053-64. PMID 4405156 DOI: 10.1016/0006-2952(72)90159-1 |
0.343 |
|
| 1973 |
Symms KG, Juchau MR. Mechanism of aromatic nitro group reduction in the soluble fraction of human placenta. Biochemical Pharmacology. 21: 2519-27. PMID 4144151 DOI: 10.1016/0006-2952(72)90423-6 |
0.373 |
|
| 1973 |
Symms KG, Juchau MR. Stabilization, solubilization, partial purification and some properties of cytochrome P-450 present in CaCl2-precipitated human placental microsomes Life Sciences. 13: 1221-1230. DOI: 10.1016/0024-3205(73)90007-6 |
0.305 |
|
| 1972 |
Juchau MR, Horita A. Metabolism of Hydrazine Derivatives of Pharmacologic Interest Drug Metabolism Reviews. 1: 71-100. DOI: 10.3109/03602537208993909 |
0.303 |
|
| 1971 |
Juchau MR. Human placental hydroxylation of 3,4-benzpyrene during early gestation and at term. Toxicology and Applied Pharmacology. 18: 665-75. PMID 4398229 DOI: 10.1016/S0041-008X(71)80021-2 |
0.33 |
|
| 1970 |
Bogdan D, Juchau MR. Charateristics of induced benzpyrene hydrylase activity in the rat foeto-placental unit. European Journal of Pharmacology. 10: 119-26. PMID 4392527 DOI: 10.1016/0014-2999(70)90167-6 |
0.374 |
|
| 1967 |
Juchau MR, Fouts JR. A comparison of assays for the analysis of protein content of liver homogenate subfractions Biochemical Pharmacology. 16: 155-161. DOI: 10.1016/0006-2952(67)90196-7 |
0.516 |
|
| 1966 |
Juchau MR, Fouts JR. Effects of 3,4-benzpyrene, phenobarbital, and chlordane on the nucleic acid and protein content of subfractions of rat liver homogenates. Biochemical Pharmacology. 15: 1453-64. PMID 5971802 DOI: 10.1016/0006-2952(66)90190-0 |
0.585 |
|
| 1966 |
Juchau MR, Gram TE, Fouts JR. Stimulation of hepatic microsomal drug-metabolizing enyme systems in primtes byDDT. Gastroenterology. 51: 213-8. PMID 4380264 |
0.532 |
|
| 1966 |
Mullen JO, Juchau MR, Fouts JR. Studies of 3,4-benzpyrene, 3-methylcholanthrene, chlordane, and methyltestosterone as stimulators of hepatic microsomal enzyme systems in the rat. Biochemical Pharmacology. 15: 137-44. PMID 4380232 DOI: 10.1016/0006-2952(66)90053-0 |
0.553 |
|
| 1966 |
Juchau MR, Fouts JR. Effects of norethynodrel and progesterone on hepatic microsomal drug-metabolizing enzyme systems Biochemical Pharmacology. 15: 891-898. DOI: 10.1016/0006-2952(66)90165-1 |
0.593 |
|
| 1965 |
CRAM RL, JUCHAU MR, FOUTS JR. DIFFERENCES IN HEPATIC DRUG METABOLISM IN VARIOUS RABBIT STRAINS BEFORE AND AFTER PRETREATMENT WITH PHENOBARBITAL. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 118: 872-5. PMID 14277699 DOI: 10.3181/00379727-118-29994 |
0.561 |
|
| 1965 |
Cram RL, Juchau MR, Fouts JR. Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey. The Journal of Laboratory and Clinical Medicine. 66: 906-11. PMID 4378995 DOI: 10.5555/Uri:Pii:0022214365900582 |
0.59 |
|
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