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Aaron R. Cooper - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Gene Therapy
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kuo CY, Long JD, Campo-Fernandez B, de Oliveira S, Cooper AR, Romero Z, Hoban MD, Joglekar AV, Lill GR, Kaufman ML, Fitz-Gibbon S, Wang X, Hollis RP, Kohn DB. Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome. Cell Reports. 23: 2606-2616. PMID 29847792 DOI: 10.1016/J.Celrep.2018.04.103  0.764
2017 Long J, Hoban MD, Cooper AR, Kaufman ML, Kuo CY, Campo-Fernandez B, Lumaquin D, Hollis RP, Wang X, Kohn DB, Romero Z. Characterization of Gene Alterations following Editing of the β-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29221806 DOI: 10.1016/J.Ymthe.2017.11.001  0.647
2017 Urbinati F, Wherley J, Geiger S, Fernandez BC, Kaufman ML, Cooper A, Romero Z, Marchioni F, Reeves L, Read E, Nowicki B, Grassman E, Viswanathan S, Wang X, Hollis RP, et al. Preclinical studies for a phase 1 clinical trial of autologous hematopoietic stem cell gene therapy for sickle cell disease. Cytotherapy. PMID 28733131 DOI: 10.1016/J.Jcyt.2017.06.002  0.657
2017 Cooper AR, Lill GR, Shaw K, Carbonaro D, Davila A, Sokolic R, Candotti F, Pellegrini M, Kohn DB. Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients. Blood. PMID 28351939 DOI: 10.1182/Blood-2016-12-756734  0.611
2017 Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, ... ... Cooper AR, et al. Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency. The Journal of Clinical Investigation. PMID 28346229 DOI: 10.1172/Jci90367  0.628
2016 Bjurström CF, Mojadidi M, Phillips J, Kuo C, Lai S, Lill GR, Cooper A, Kaufman M, Urbinati F, Wang X, Hollis RP, Kohn DB. Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases. Molecular Therapy. Nucleic Acids. 5: e351. PMID 28131278 DOI: 10.1038/Mtna.2016.52  0.656
2016 Hoban MD, Lumaquin D, Kuo CY, Romero Z, Long J, Ho M, Young CS, Mojadidi M, Fitz-Gibbon S, Cooper AR, Lill GR, Urbinati F, Campo-Fernandez B, Bjurstrom CF, Pellegrini M, et al. CRISPR/Cas9-mediated correction of the sickle mutation in human CD34+ cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27406980 DOI: 10.1038/Mt.2016.148  0.669
2016 Chin CJ, Cooper AR, Lill GR, Evseenko D, Zhu Y, He CB, Casero D, Pellegrini M, Kohn DB, Crooks GM. Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells (Dayton, Ohio). PMID 26934332 DOI: 10.1002/Stem.2351  0.593
2016 Bjurström CF, Mojadidi M, Lomova A, Lai S, Fitz-Gibbon S, Pellegrini M, Cooper AR, Lill GR, Kaufman M, Cost GJ, Holmes MC, Hollis RP, Kohn DB. Preservation of Gene Edited Hematopoietic Stem Cells By Transient Overexpression of BCL-2 mRNA Blood. 128: 3636-3636. DOI: 10.1182/Blood.V128.22.3636.3636  0.675
2016 Long J, Hoban MD, Kuo CY, Fernandez BC, Cooper AR, Lumaquin D, Hollis RP, Kohn DB, Romero Z. 118. Characterization of Chromosomal Alterations Using a Zinc-Finger Nuclease Targeting the Beta-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32927-6  0.576
2015 Romero Z, Campo-Fernandez B, Wherley J, Kaufman ML, Urbinati F, Cooper AR, Hoban MD, Baldwin KM, Lumaquin D, Wang X, Senadheera S, Hollis RP, Kohn DB. The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. Molecular Therapy. Methods & Clinical Development. 2: 15012. PMID 26029723 DOI: 10.1038/Mtm.2015.12  0.62
2015 Hoban MD, Cost GJ, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR, Cooper AR, Urbinati F, Senadheera S, Zhu A, Liu PQ, et al. Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells. Blood. 125: 2597-604. PMID 25733580 DOI: 10.1182/Blood-2014-12-615948  0.766
2015 Baldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman ML, Cooper AR, Masiuk K, Hollis RP, Kohn DB. Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells (Dayton, Ohio). 33: 1532-42. PMID 25588820 DOI: 10.1002/Stem.1957  0.597
2015 Cooper AR, Lill GR, Gschweng EH, Kohn DB. Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. Nucleic Acids Research. 43: 682-90. PMID 25520191 DOI: 10.1093/Nar/Gku1312  0.533
2015 Cooper AR, Shaw KL, Lill GR, Sokolic R, Candotti F, Kohn DB. 240. Stable and Clinically Benign Clonal Dominance in an ADA-SCID Patient Treated With Retroviral Gene Therapy Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33845-X  0.614
2015 Hoban MD, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR, Cooper AR, Urbinati F, Senadheera S, Zhu A, Liu P, Paschon DE, et al. 115. Correction of the Sickle-Cell Disease Mutation in Human Hematopoietic Stem/Progenitor Cells Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33720-0  0.731
2015 Shaw KL, Garabedian E, Sokolic R, Barman P, Davila A, Silvin C, Oliveira Sd, Shah AJ, Terrazas D, Carbonaro D, Geiger S, Mishra S, Cooper A, Smogorzewska M, Jagadeesh J, et al. 30. Phase II Clinical Trial of Gene Therapy for Adenosine Deaminase-Deficient Severe Combined Immune Deficiency (ADA-SCID) Using a γ-Retroviral Vector Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33634-6  0.574
2014 Carbonaro DA, Zhang L, Jin X, Montiel-Equihua C, Geiger S, Carmo M, Cooper A, Fairbanks L, Kaufman ML, Sebire NJ, Hollis RP, Blundell MP, Senadheera S, Fu PY, Sahaghian A, et al. Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 607-22. PMID 24256635 DOI: 10.1038/Mt.2013.265  0.642
2013 Stoyanova T, Cooper AR, Drake JM, Liu X, Armstrong AJ, Pienta KJ, Zhang H, Kohn DB, Huang J, Witte ON, Goldstein AS. Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 20111-6. PMID 24282295 DOI: 10.1073/Pnas.1320565110  0.558
2013 Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, et al. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Research & Therapy. 4: 87. PMID 23890092 DOI: 10.1186/Scrt246  0.667
2013 Romero Z, Urbinati F, Geiger S, Cooper AR, Wherley J, Kaufman ML, Hollis RP, de Assin RR, Senadheera S, Sahagian A, Jin X, Gellis A, Wang X, Gjertson D, Deoliveira S, et al. β-globin gene transfer to human bone marrow for sickle cell disease. The Journal of Clinical Investigation. PMID 23863630 DOI: 10.1172/Jci67930  0.686
2013 McCracken MN, Gschweng EH, Nair-Gill E, McLaughlin J, Cooper AR, Riedinger M, Cheng D, Nosala C, Kohn DB, Witte ON. Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene. Proceedings of the National Academy of Sciences of the United States of America. 110: 1857-62. PMID 23319634 DOI: 10.1073/Pnas.1221840110  0.63
2012 Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001  0.595
2012 Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, et al. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood. 120: 3635-46. PMID 22968453 DOI: 10.1182/Blood-2012-02-400937  0.688
2011 Cooper AR, Patel S, Senadheera S, Plath K, Kohn DB, Hollis RP. Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. Journal of Virological Methods. 177: 1-9. PMID 21784103 DOI: 10.1016/J.Jviromet.2011.06.019  0.543
2011 von Levetzow C, Jiang X, Gwye Y, von Levetzow G, Hung L, Cooper A, Hsu JH, Lawlor ER. Modeling initiation of Ewing sarcoma in human neural crest cells. Plos One. 6: e19305. PMID 21559395 DOI: 10.1371/Journal.Pone.0019305  0.53
2011 Cooper A, van Doorninck J, Ji L, Russell D, Ladanyi M, Shimada H, Krailo M, Womer RB, Hsu JH, Thomas D, Triche TJ, Sposto R, Lawlor ER. Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 56-66. PMID 21047978 DOI: 10.1158/1078-0432.Ccr-10-1417  0.338
2011 Urbinati F, Garcia ZR, Geiger S, de Assin RR, Kuftinec G, Hollis RP, Oliveira SND, Wherley J, Cooper A, Townes TM, Crooks GM, Read EJ, Walters MC, Meiselman HJ, Coates TD, et al. Preclinical Studies for Sickle Cell Disease Gene Therapy Using Bone Marrow CD34+ Cells Modified with a βAS3-Globin Lentiviral Vector Blood. 118: 3119-3119. DOI: 10.1182/Blood.V118.21.3119.3119  0.708
2010 Bennani-Baiti IM, Cooper A, Lawlor ER, Kauer M, Ban J, Aryee DN, Kovar H. Intercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3769-78. PMID 20525755 DOI: 10.1158/1078-0432.Ccr-10-0558  0.325
2010 Levetzow Cv, Jiang X, Gwye Y, Hung L, Levetzow Gv, Cooper A, Hsu JH, Lawlor ER. Abstract 4239: Ectopic expression of EWS-FLI1 in human neural crest stem cells induces polycomb genes and maintenance of stemness Cancer Research. 70: 4239-4239. DOI: 10.1158/1538-7445.Am10-4239  0.55
2010 Bennani-Baiti IM, Lawlor ER, Cooper A, Kauer M, Ban J, Aryee DNT, Kovar H. Abstract 3410: Discovery of prognostic factors in Ewing's sarcoma family of tumors by use of Intercohort co-analysis of public gene expression datasets Cancer Research. 70: 3410-3410. DOI: 10.1158/1538-7445.Am10-3410  0.374
2008 Douglas D, Hsu JH, Hung L, Cooper A, Abdueva D, van Doorninck J, Peng G, Shimada H, Triche TJ, Lawlor ER. BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression. Cancer Research. 68: 6507-15. PMID 18701473 DOI: 10.1158/0008-5472.Can-07-6152  0.406
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