David G Fernig - Publications

University of Liverpool, LIVERPOOL, UK. 
growth factors, glycosaminoglycans, receptor tyrosine kinases, signaling, nanoparticles, extracellular matrix

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li Y, Sun C, Yates EA, Jiang C, Wilkinson MC, Fernig DG. Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification. Open Biology. 6. PMID 27030175 DOI: 10.1098/Rsob.150275  0.6
2015 Lee J, Wee S, Gunaratne J, Chua RJ, Smith RA, Ling L, Fernig DG, Swaminathan K, Nurcombe V, Cool SM. Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signalling. Glycobiology. PMID 26306634 DOI: 10.1093/Glycob/Cwv064  0.36
2015 Migliorini E, Thakar D, Kühnle J, Sadir R, Dyer DP, Li Y, Sun C, Volkman BF, Handel TM, Coche-Guerente L, Fernig DG, Lortat-Jacob H, Richter RP. Cytokines and growth factors cross-link heparan sulfate. Open Biology. 5. PMID 26269427 DOI: 10.1098/Rsob.150046  0.36
2015 Sun C, Li Y, Taylor SE, Mao X, Wilkinson MC, Fernig DG. HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors. Peerj. 3: e1060. PMID 26137434 DOI: 10.7717/Peerj.1060  0.36
2015 Paramelle D, Nieves D, Brun B, Kraut RS, Fernig DG. Targeting Cell Membrane Lipid Rafts by Stoichiometric Functionalization of Gold Nanoparticles With a Sphingolipid-Binding Domain Peptide. Advanced Healthcare Materials. 4: 911-7. PMID 25650337 DOI: 10.1002/Adhm.201400730  0.36
2015 Hughes AJ, Rudd TR, Wright GSA, Fernig DG, Siligardi G, Yates EA. Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism Analytical Methods. 7: 1667-1671. DOI: 10.1039/C4Ay02618G  0.36
2014 Nieves DJ, Azmi NS, Xu R, Lévy R, Yates EA, Fernig DG. Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry. Chemical Communications (Cambridge, England). 50: 13157-60. PMID 25227324 DOI: 10.1039/C4Cc05909C  0.36
2014 Uniewicz KA, Ori A, Ahmed YA, Yates EA, Fernig DG. Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars. Peerj. 2: e461. PMID 25024924 DOI: 10.7717/Peerj.461  0.36
2014 Mournetas V, Nunes QM, Murray PA, Sanderson CM, Fernig DG. Network based meta-analysis prediction of microenvironmental relays involved in stemness of human embryonic stemcells Peerj. 2014. DOI: 10.7717/peerj.618  0.36
2013 Xu R, Rudd TR, Hughes AJ, Siligardi G, Fernig DG, Yates EA. Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network. The Febs Journal. 280: 2260-70. PMID 23441759 DOI: 10.1111/Febs.12201  0.36
2012 Fernig D, Boraston AB. Glycans: Pervasive regulators of protein and cellular function Current Opinion in Structural Biology. 22: 537-539. PMID 23083921 DOI: 10.1016/J.Sbi.2012.09.003  0.36
2012 Xu R, Ori A, Rudd TR, Uniewicz KA, Ahmed YA, Guimond SE, Skidmore MA, Siligardi G, Yates EA, Fernig DG. Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity. The Journal of Biological Chemistry. 287: 40061-73. PMID 23019343 DOI: 10.1074/Jbc.M112.398826  0.36
2012 Du M, Wang G, Ismail TM, Gross S, Fernig DG, Barraclough R, Rudland PS. S100P dissociates myosin IIA filaments and focal adhesion sites to reduce cell adhesion and enhance cell migration. The Journal of Biological Chemistry. 287: 15330-44. PMID 22399300 DOI: 10.1074/Jbc.M112.349787  0.72
2012 Taylor A, Wilson KM, Murray P, Fernig DG, Lévy R. Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet? Chemical Society Reviews. 41: 2707-17. PMID 22362426 DOI: 10.1039/C2Cs35031A  0.36
2012 Uniewicz KA, Ori A, Rudd TR, Guerrini M, Wilkinson MC, Fernig DG, Yates EA. Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry. Methods in Molecular Biology (Clifton, N.J.). 836: 171-82. PMID 22252635 DOI: 10.1007/978-1-61779-498-8_12  0.36
2012 Holder GM, Bowfield A, Surman M, Suepfle M, Moss D, Tucker C, Rudd TR, Fernig DG, Yates EA, Weightman P. Fundamental differences in model cell-surface polysaccharides revealed by complementary optical and spectroscopic techniques Soft Matter. 8: 6521-6527. DOI: 10.1039/C2Sm25239B  0.36
2011 Thompson SM, Connell MG, van Kuppevelt TH, Xu R, Turnbull JE, Losty PD, Fernig DG, Jesudason EC. Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation? Bmc Developmental Biology. 11: 38. PMID 21672206 DOI: 10.1186/1471-213X-11-38  0.36
2011 Ori A, Wilkinson MC, Fernig DG. A systems biology approach for the investigation of the heparin/heparan sulfate interactome. The Journal of Biological Chemistry. 286: 19892-904. PMID 21454685 DOI: 10.1074/Jbc.M111.228114  0.6
2011 Scullion L, Doneux T, Bouffier L, Fernig DG, Higgins SJ, Bethell D, Nichols RJ. Large conductance changes in peptide single molecule junctions controlled by pH Journal of Physical Chemistry C. 115: 8361-8368. DOI: 10.1021/Jp201222B  0.36
2010 Bruning M, Kreplak L, Leopoldseder S, Müller SA, Ringler P, Duchesne L, Fernig DG, Engel A, Ucurum-Fotiadis Z, Mayans O. Bipartite design of a self-fibrillating protein copolymer with nanopatterned peptide display capabilities. Nano Letters. 10: 4533-7. PMID 20954695 DOI: 10.1021/Nl1024886  0.36
2010 Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA. Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. Organic & Biomolecular Chemistry. 8: 5390-7. PMID 20865198 DOI: 10.1039/C0Ob00246A  0.36
2010 Zhu H, Duchesne L, Rudland PS, Fernig DG. The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor. Cell Communication and Signaling : Ccs. 8: 14. PMID 20576134 DOI: 10.1186/1478-811X-8-14  0.72
2010 Uniewicz KA, Ori A, Xu R, Ahmed Y, Wilkinson MC, Fernig DG, Yates EA. Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity. Analytical Chemistry. 82: 3796-802. PMID 20353159 DOI: 10.1021/Ac100188X  0.36
2010 Ismail TM, Zhang S, Fernig DG, Gross S, Martin-Fernandez ML, See V, Tozawa K, Tynan CJ, Wang G, Wilkinson MC, Rudland PS, Barraclough R. Self-association of calcium-binding protein S100A4 and metastasis. The Journal of Biological Chemistry. 285: 914-22. PMID 19917604 DOI: 10.1074/Jbc.M109.010892  0.72
2009 Rudd TR, Skidmore MA, Guimond SE, Holman J, Turnbull JE, Lauder RM, Fernig DG, Yates EA. The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids. Thrombosis and Haemostasis. 102: 874-8. PMID 19888522 DOI: 10.1160/Th08-12-0797  0.36
2009 Sée V, Free P, Cesbron Y, Nativo P, Shaheen U, Rigden DJ, Spiller DG, Fernig DG, White MR, Prior IA, Brust M, Lounis B, Lévy R. Cathepsin L digestion of nanobioconjugates upon endocytosis. Acs Nano. 3: 2461-8. PMID 19728690 DOI: 10.1021/Nn9006994  0.36
2009 Daghestani HN, Fernig DG, Day BW. Evaluation of biosensor surfaces for the detection of microtubule perturbation. Biosensors & Bioelectronics. 25: 136-41. PMID 19595587 DOI: 10.1016/J.Bios.2009.06.014  0.36
2009 Ori A, Free P, Courty J, Wilkinson MC, Fernig DG. Identification of heparin-binding sites in proteins by selective labeling. Molecular & Cellular Proteomics : McP. 8: 2256-65. PMID 19567366 DOI: 10.1074/Mcp.M900031-Mcp200  0.6
2009 Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA. Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution. Biochemistry. 48: 4772-9. PMID 19400583 DOI: 10.1021/Bi802318Z  0.36
2009 Rudd TR, Skidmore MA, Guimond SE, Cosentino C, Torri G, Fernig DG, Lauder RM, Guerrini M, Yates EA. Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra. Glycobiology. 19: 52-67. PMID 18832453 DOI: 10.1093/Glycob/Cwn103  0.36
2009 Smith CI, Bowfield A, Cuquerella MC, Mansley CP, Farrell T, Harrison P, Martin DS, Fernig DG, Edwards C, Butler JE, Hamers RJ, Sun B, Wang X, Weightman P. Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy Europhysics Letters. 85. DOI: 10.1209/0295-5075/85/18006  0.36
2008 Kurisetty VV, Johnston PG, Johnston N, Erwin P, Crowe P, Fernig DG, Campbell FC, Anderson IP, Rudland PS, El-Tanani MK. RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin. Oncogene. 27: 7139-49. PMID 18794800 DOI: 10.1038/Onc.2008.325  0.36
2008 Ismail TM, Fernig DG, Rudland PS, Terry CJ, Wang G, Barraclough R. The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. Carcinogenesis. 29: 2259-66. PMID 18784356 DOI: 10.1093/Carcin/Bgn217  0.72
2008 Skidmore MA, Guimond SE, Rudd TR, Fernig DG, Turnbull JE, Yates EA. The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation. Connective Tissue Research. 49: 140-4. PMID 18661329 DOI: 10.1080/03008200802148595  0.36
2008 Ori A, Wilkinson MC, Fernig DG. The heparanome and regulation of cell function: structures, functions and challenges. Frontiers in Bioscience. 13: 4309-4338. PMID 18508513 DOI: 10.2741/3007  0.6
2008 Rudd TR, Skidmore MA, Guimond SE, Guerrini M, Cosentino C, Edge R, Brown A, Clarke DT, Torri G, Turnbull JE, Nichols RJ, Fernig DG, Yates EA. Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques. Carbohydrate Research. 343: 2184-93. PMID 18226804 DOI: 10.1016/J.Carres.2007.12.019  0.36
2008 Catlow KR, Deakin JA, Wei Z, Delehedde M, Fernig DG, Gherardi E, Gallagher JT, Pavão MS, Lyon M. Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. The Journal of Biological Chemistry. 283: 5235-48. PMID 18156180 DOI: 10.1074/Jbc.M706589200  0.44
2008 Lu LT, Tung LD, Robinson I, Ung D, Tan B, Long J, Cooper AI, Fernig DG, Thanh NTK. Size and shape control for water-soluble magnetic cobalt nanoparticles using polymer ligands Journal of Materials Chemistry. 18: 2453-2458. DOI: 10.1039/B801800F  0.36
2008 Nichols RJ, Haiss W, Fernig DG, Zalinge HV, Schiffrin DJ, Ulstrup J. In situ STM studies of immobilized biomolecules at the electrodeelectrolyte interface Bioinorganic Electrochemistry. 207-247. DOI: 10.1007/978-1-4020-6500-2_7  0.36
2007 Vanpouille C, Deligny A, Delehedde M, Denys A, Melchior A, Liénard X, Lyon M, Mazurier J, Fernig DG, Allain F. The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. The Journal of Biological Chemistry. 282: 24416-29. PMID 17588944 DOI: 10.1074/Jbc.M701835200  0.4
2007 Rudd TR, Guimond SE, Skidmore MA, Duchesne L, Guerrini M, Torri G, Cosentino C, Brown A, Clarke DT, Turnbull JE, Fernig DG, Yates EA. Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives. Glycobiology. 17: 983-93. PMID 17580314 DOI: 10.1093/Glycob/Cwm062  0.36
2006 Featherstone NC, Connell MG, Fernig DG, Wray S, Burdyga TV, Losty PD, Jesudason EC. Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis. American Journal of Respiratory Cell and Molecular Biology. 35: 571-8. PMID 16728706 DOI: 10.1165/Rcmb.2006-0079Oc  0.36
2006 Yates EA, Terry CJ, Rees C, Rudd TR, Duchesne L, Skidmore MA, Lévy R, Thanh NT, Nichols RJ, Clarke DT, Fernig DG. Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes. Biochemical Society Transactions. 34: 427-30. PMID 16709178 DOI: 10.1042/Bst0340427  0.36
2006 Jesudason EC, Smith NP, Connell MG, Spiller DG, White MR, Fernig DG, Losty PD. Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L559-65. PMID 16603591 DOI: 10.1152/ajplung.00498.2005  0.36
2006 Terry CJ, Popplewell JF, Swann MJ, Freeman NJ, Fernig DG. Characterisation of membrane mimetics on a dual polarisation interferometer Biosensors and Bioelectronics. 22: 627-632. PMID 16530399 DOI: 10.1016/J.Bios.2006.01.021  0.4
2006 Wang Z, Lévy R, Fernig DG, Brust M. Kinase-catalyzed modification of gold nanoparticles: a new approach to colorimetric kinase activity screening. Journal of the American Chemical Society. 128: 2214-5. PMID 16478166 DOI: 10.1021/Ja058135Y  0.36
2006 Lévy R, Wang Z, Duchesne L, Doty RC, Cooper AI, Brust M, Fernig DG. A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography. Chembiochem : a European Journal of Chemical Biology. 7: 592-4. PMID 16470890 DOI: 10.1002/Cbic.200500457  0.36
2005 Wang Z, Lévy R, Fernig DG, Brust M. The peptide route to multifunctional gold nanoparticles. Bioconjugate Chemistry. 16: 497-500. PMID 15898714 DOI: 10.1021/Bc050047F  0.36
2005 Featherstone NC, Jesudason EC, Connell MG, Fernig DG, Wray S, Losty PD, Burdyga TV. Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung. American Journal of Respiratory Cell and Molecular Biology. 33: 153-60. PMID 15891108 DOI: 10.1165/Rcmb.2005-0137Oc  0.36
2005 Zhang S, Wang G, Liu D, Bao Z, Fernig DG, Rudland PS, Barraclough R. The C-terminal region of S100A4 is important for its metastasis-inducing properties Oncogene. 24: 4401-4411. PMID 15856021 DOI: 10.1038/Sj.Onc.1208663  0.36
2005 West DC, Rees CG, Duchesne L, Patey SJ, Terry CJ, Turnbull JE, Delehedde M, Heegaard CW, Allain F, Vanpouille C, Ron D, Fernig DG. Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. The Journal of Biological Chemistry. 280: 13457-64. PMID 15695515 DOI: 10.1074/Jbc.M410924200  0.36
2005 Wang G, Zhang S, Fernig DG, Martin-Fernandez M, Rudland PS, Barraclough R. Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes. Oncogene. 24: 1445-54. PMID 15608682 DOI: 10.1038/Sj.Onc.1208291  0.72
2005 Zhang S, Wang G, Fernig DG, Rudland PS, Webb SE, Barraclough R, Martin-Fernandez M. Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy. European Biophysics Journal : Ebj. 34: 19-27. PMID 15289939 DOI: 10.1007/S00249-004-0428-X  0.72
2005 Doty RC, Tshikhudo TR, Brust M, Fernig DG. Extremely stable water-soluble Ag nanoparticles Chemistry of Materials. 17: 4630-4635. DOI: 10.1021/Cm0508017  0.36
2004 Skidmore MA, Patey SJ, Thanh NT, Fernig DG, Turnbull JE, Yates EA. Attachment of glycosaminoglycan oligosaccharides to thiol-derivatised gold surfaces. Chemical Communications (Cambridge, England). 2700-1. PMID 15568074 DOI: 10.1039/B411726C  0.36
2004 Lévy R, Thanh NT, Doty RC, Hussain I, Nichols RJ, Schiffrin DJ, Brust M, Fernig DG. Rational and combinatorial design of peptide capping ligands for gold nanoparticles. Journal of the American Chemical Society. 126: 10076-84. PMID 15303884 DOI: 10.1021/Ja0487269  0.36
2004 Wang G, Zhang S, Fernig DG, Spiller D, Martin-Fernandez M, Zhang H, Ding Y, Rao Z, Rudland PS, Barraclough R. Heterodimeric interaction and interfaces of S100A1 and S100P. The Biochemical Journal. 382: 375-83. PMID 15171681 DOI: 10.1042/Bj20040142  0.72
2004 Powell AK, Yates EA, Fernig DG, Turnbull JE. Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches. Glycobiology. 14: 17R-30R. PMID 14718374 DOI: 10.1093/Glycob/Cwh051  0.36
2003 Catlow K, Deakin JA, Delehedde M, Fernig DG, Gallagher JT, Pavão MS, Lyon M. Hepatocyte growth factor/scatter factor and its interaction with heparan sulphate and dermatan sulphate. Biochemical Society Transactions. 31: 352-3. PMID 12653636 DOI: 10.1042/Bst0310352  0.44
2003 Rudd T, Gallagher JT, Ron D, Nichols RJ, Fernig DG. A gravimetric analysis of protein-oligosaccharide interactions. Biochemical Society Transactions. 31: 349-51. PMID 12653635 DOI: 10.1042/Bst0310349  0.44
2003 Zhang H, Wang G, Ding Y, Wang Z, Barraclough R, Rudland PS, Fernig DG, Rao Z. The crystal structure at 2A resolution of the Ca2+ -binding protein S100P. Journal of Molecular Biology. 325: 785-94. PMID 12507480 DOI: 10.1016/S0022-2836(02)01278-0  0.72
2002 Delehedde M, Lyon M, Gallagher JT, Rudland PS, Fernig DG. Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts. The Biochemical Journal. 366: 235-44. PMID 12000311 DOI: 10.1042/Bj20011718  0.72
2002 Delehedde M, Lyon M, Vidyasagar R, McDonnell TJ, Fernig DG. Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes. The Journal of Biological Chemistry. 277: 12456-62. PMID 11799124 DOI: 10.1074/Jbc.M111345200  0.4
2002 Ostrovsky O, Berman B, Gallagher J, Mulloy B, Fernig DG, Delehedde M, Ron D. Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes. The Journal of Biological Chemistry. 277: 2444-53. PMID 11714710 DOI: 10.1074/Jbc.M108540200  0.4
2001 Béchard D, Gentina T, Delehedde M, Scherpereel A, Lyon M, Aumercier M, Vazeux R, Richet C, Degand P, Jude B, Janin A, Fernig DG, Tonnel AB, Lassalle P. Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity. The Journal of Biological Chemistry. 276: 48341-9. PMID 11590178 DOI: 10.1074/Jbc.M108395200  0.4
2001 Delehedde M, Lyon M, Sergeant N, Rahmoune H, Fernig DG. Proteoglycans: Pericellular and Cell Surface Multireceptors that Integrate External Stimuli in the Mammary Gland Journal of Mammary Gland Biology and Neoplasia. 6: 253-273. PMID 11547896 DOI: 10.1023/A:1011367423085  0.44
2001 Chen H, Fernig DG, Rudland PS, Sparks A, Wilkinson MC, Barraclough R. Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka). Biochemical and Biophysical Research Communications. 286: 1212-7. PMID 11527429 DOI: 10.1006/Bbrc.2001.5517  0.72
2001 El-Tanani M, Fernig DG, Barraclough R, Green C, Rudland P. Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors. Journal of Biological Chemistry. 276: 41675-41682. PMID 11522780 DOI: 10.1074/Jbc.M103966200  0.72
2001 Delehedde M, Sergeant N, Lyon M, Rudland PS, Fernig DG. Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways. Febs Journal. 268: 4423-4429. PMID 11502202 DOI: 10.1046/J.1432-1327.2001.02363.X  0.72
2001 Singh R, Campbell BJ, Yu LG, Fernig DG, Milton JD, Goodlad RA, FitzGerald AJ, Rhodes JM. Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44. Glycobiology. 11: 587-92. PMID 11447138 DOI: 10.1093/Glycob/11.7.587  0.36
2001 Jesudason EC, Connell MG, Fernig DG, Lloyd DA, Losty PD. Does the developing liver inhibit early lung growth in congenital diaphragmatic hernia? Pediatric Surgery International. 17: 288-293. PMID 11409164 DOI: 10.1007/S003830100596  0.36
2000 Delehedde M, Seve M, Sergeant N, Wartelle I, Lyon M, Rudland PS, Fernig DG. Fibroblast growth factor-2 stimulation of p42/44MAPK phosphorylation and IkappaB degradation is regulated by heparan sulfate/heparin in rat mammary fibroblasts. Journal of Biological Chemistry. 275: 33905-33910. PMID 10944532 DOI: 10.1074/Jbc.M005949200  0.72
2000 Jesudason EC, Connell MG, Fernig DG, Lloyd DA, Losty PD. Heparin and in-vitro experimental lung hypoplasia Pediatric Surgery International. 16: 247-251. PMID 10898223 DOI: 10.1007/S003830050738  0.36
2000 Jesudason EC, Connell MG, Fernig DG, Lloyd DA, Losty PD. In vitro effects of growth factors on lung hypoplasia in a model of congenital diaphragmatic hernia Journal of Pediatric Surgery. 35: 914-922. PMID 10873035 DOI: 10.1053/Jpsu.2000.6919  0.36
2000 Sergeant N, Lyon M, Rudland PS, Fernig DG, Delehedde M. Stimulation of DNA Synthesis and Cell Proliferation of Human Mammary Myoepithelial-like Cells by Hepatocyte Growth Factor/Scatter Factor Depends on Heparan Sulfate Proteoglycans and Sustained Phosphorylation of Mitogen-activated Protein Kinases p42/44 Journal of Biological Chemistry. 275: 17094-17099. PMID 10747885 DOI: 10.1074/Jbc.M000237200  0.72
2000 Fernig DG, Chen H, Rahmoune H, Descamps S, Boilly B, Hondermarck H. Differential Regulation of FGF-1 and -2 Mitogenic Activity Is Related to Their Kinetics of Binding to Heparan Sulfate in MDA-MB-231 Human Breast Cancer Cells Biochemical and Biophysical Research Communications. 267: 770-776. PMID 10673367 DOI: 10.1006/Bbrc.1999.2028  0.44
2000 Jesudason EC, Connell MG, Fernig DG, Lloyd DA, Losty PD. Cell proliferation and apoptosis in experimental lung hypoplasia Journal of Pediatric Surgery. 35: 129-133. PMID 10646790 DOI: 10.1016/S0022-3468(00)80029-9  0.36
2000 Jesudason EC, Connel MG, Fernig DG, Lloyd DA, Losty PD. Early lung malformations in congenital diaphragmatic hernia Journal of Pediatric Surgery. 35: 124-128. PMID 10646789 DOI: 10.1016/S0022-3468(00)80028-7  0.36
1999 Li P, Wilde CJ, Finch LM, Fernig DG, Rudland PS. Identification of cell types in the developing goat mammary gland. The Histochemical Journal. 31: 379-93. PMID 10462224 DOI: 10.1023/A:1003700224900  0.36
1999 Li P, Rudland PS, Fernig DG, Finch LM, Wilde CJ. Modulation of mammary development and programmed cell death by the frequency of milk removal in lactating goats. The Journal of Physiology. 519: 885-900. PMID 10457098 DOI: 10.1111/J.1469-7793.1999.0885N.X  0.36
1999 Yu LG, Fernig DG, White MR, Spiller DG, Appleton P, Evans RC, Grierson I, Smith JA, Davies H, Gerasimenko OV, Petersen OH, Milton JD, Rhodes JM. Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import. The Journal of Biological Chemistry. 274: 4890-9. PMID 9988731 DOI: 10.1074/Jbc.274.8.4890  0.36
1998 Li P, Barraclough R, Fernig DG, Smith JA, Rudland PS. Stem cells in breast epithelia. International Journal of Experimental Pathology. 79: 193-206. PMID 9797716 DOI: 10.1046/J.1365-2613.1998.00068.X  0.72
1998 Wilkinson MC, Fernig DG, Smith JA, Nunez de Croker CA, Rudland PS. Ferritin and hemoglobin in pituitary gland extracts are mitogenic for rat mammary epithelial cells in culture. In Vitro Cellular & Developmental Biology. Animal. 34: 518-9. PMID 9719408 DOI: 10.1007/S11626-998-0108-8  0.6
1998 Rahmoune H, Rudland PS, Gallagher JT, Fernig DG. Hepatocyte growth factor/scatter factor has distinct classes of binding site in heparan sulfate from mammary cells. Biochemistry. 37: 6003-6008. PMID 9558337 DOI: 10.1021/Bi972468T  0.72
1998 Rahmoune H, Chen H, Gallagher JT, Rudland PS, Fernig DG. Interaction of Heparan Sulfate from Mammary Cells with Acidic Fibroblast Growth Factor (FGF) and Basic FGF REGULATION OF THE ACTIVITY OF BASIC FGF BY HIGH AND LOW AFFINITY BINDING SITES IN HEPARAN SULFATE Journal of Biological Chemistry. 273: 7303-7310. PMID 9516424 DOI: 10.1074/Jbc.273.13.7303  0.72
1998 Lyon M, Deakin JA, Rahmoune H, Fernig DG, Nakamura T, Gallagher JT. Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate Journal of Biological Chemistry. 273: 271-278. PMID 9417075 DOI: 10.1074/Jbc.273.1.271  0.44
1997 Yu LG, Jansson B, Fernig DG, Milton JD, Smith JA, Gerasimenko OV, Jones M, Rhodes JM. Stimulation of proliferation in human colon cancer cells by human monoclonal antibodies against the TF antigen (galactose beta1-3 N-acetyl-galactosamine). International Journal of Cancer. Journal International Du Cancer. 73: 424-31. PMID 9359491 DOI: 10.1002/(Sici)1097-0215(19971104)73:3<424::Aid-Ijc18>3.0.Co;2-C  0.72
1997 Wilde CJ, Addey CVP, Li P, Fernig DG. Programmed cell death in bovine mammary tissue during lactation and involution Experimental Physiology. 82: 943-953. PMID 9331560 DOI: 10.1113/Expphysiol.1997.Sp004075  0.48
1997 Galzie Z, Fernig DG, Smith JA, Poston GJ, Kinsella AR. Invasion of human colorectal carcinoma cells is promoted by endogenous basic fibroblast growth factor. International Journal of Cancer. 71: 390-395. PMID 9139874 DOI: 10.1002/(Sici)1097-0215(19970502)71:3<390::Aid-Ijc15>3.0.Co;2-K  0.72
1997 Rudland PS, Barraclough R, Fernig DG, Smith JA. 7 – Mammary stem cells in normal development and cancer Stem Cells. 147-232. DOI: 10.1016/B978-012563455-7/50008-8  0.72
1996 Galzie Z, Fernig DG, Smith JA, Poston GJ, Kinsella AR. Basic fibroblast growth factor and colorectal carcinoma invasion Biochemical Society Transactions. 24. PMID 8879045 DOI: 10.1042/Bst024501S  0.72
1996 Chen H, Smith JA, Rudland PS, Fernig DG. Potentiation of the growth-stimulatory effects of aFGF by heparin in Rama 27 fibroblasts. Biochemical Society Transactions. 24. PMID 8878902 DOI: 10.1042/Bst024358S  0.72
1996 Li P, Fernig DG, Rudland PS, Finch LM, Wilde CJ. Identification of cell types in the developing goat mammary gland. Biochemical Society Transactions. 24: 357S. PMID 8878901 DOI: 10.1042/Bst024357S  0.72
1996 Chen H, Rudland PS, Smith JA, Fernig DG. Late signals are required for the stimulation of DNA synthesis in rat mammary fibroblasts by growth factors. Bioscience Reports. 16: 249-263. PMID 8842375 DOI: 10.1007/Bf01207339  0.72
1996 Davies BR, Fernig DG, Barraclough R, Rudland PS. Effect on tumorigenicity and metastasis of transfection of a diploid benign rat mammary epithelial cell line with DNA corresponding to the mRNA for basic fibroblast growth factor International Journal of Cancer. 65: 104-111. PMID 8543386 DOI: 10.1002/(Sici)1097-0215(19960103)65:1<104::Aid-Ijc18>3.0.Co;2-G  0.72
1995 Rudland P, Fernig D, Smith J. Growth factors and their receptors in neoplastic mammary glands. Biomedicine & Pharmacotherapy. 49: 389-399. PMID 8746075 DOI: 10.1016/0753-3322(96)82676-X  0.32
1995 Yu LG, Evans RC, Davies H, Ward S, Miller G, Grierson I, Fernig DG, Smith JA, Milton JD, Rhodes JM. Demonstration of Internalization and Nuclear Incorporation of the Growth Inhibitory Lectin from Edible Mushroom Clinical Science. 88. DOI: 10.1042/Cs088011Pa  0.72
1995 Yu LG, Fernig DG, Davies H, Ward S, Smith JA, Grierson I, Miller G, Evans RC, Milton JD, Rhodes JM. Internalization and nuclear incorporation of the growth inhibitory lectin from edible mushroom by HT29 colon cancer cells Gastroenterology. 108. DOI: 10.1016/0016-5085(95)26544-9  0.72
1994 McAndrew J, Fernig DG, Rudland PS, Smith JA. Secretion of transforming growth factor alpha and expression of its receptor in human mammary cell lines. Growth Factors Journal. 10: 281-287. PMID 7803044 DOI: 10.3109/08977199409010994  0.72
1994 Fernig DG, Gallagher JT. Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair. Progress in Growth Factor Research. 5: 353-377. PMID 7780086 DOI: 10.1016/0955-2235(94)00007-8  0.44
1993 Fernig DG, Barraclough R, Ke Y, Wilkinson MC, Rudland PS, Smith JA. Ectopic production of heparin-binding growth factors and receptors for basic fibroblast growth factor by rat mammary epithelial cell lines derived from malignant metastatic tumours. International Journal of Cancer. 54: 629-635. PMID 8514454 DOI: 10.1002/Ijc.2910540418  0.72
1993 Rudland PS, Platt-Higgins AM, Wilkinson MC, Fernig DG. Immunocytochemical identification of basic fibroblast growth factor in the developing rat mammary gland: variations in location are dependent on glandular structure and differentiation.: Journal of Histochemistry and Cytochemistry. 41: 887-898. PMID 7686196 DOI: 10.1177/41.6.7686196  0.72
1992 Ke Y, Wilkinson MC, Fernig DG, Smith JA, Rudland PS, Barraclough R. A rapid procedure for production of human basic fibroblast growth factor in Escherichia coli cells. Biochimica Et Biophysica Acta. 1131: 307-310. PMID 1627646 DOI: 10.1016/0167-4781(92)90029-Y  0.72
1992 Fernig DG, Rudland PS, Smith JA. Rat mammary myoepithelial-like cells in culture possess kinetically distinct low-affinity receptors for fibroblast growth factor that modulate growth stimulatory responses. Growth Factors Journal. 7: 27-39. PMID 1323979 DOI: 10.3109/08977199209023935  0.72
1991 Fernig DG, Smith JA, Rudland PS. Relationship of growth factors and differentiation in normal and neoplastic development of the mammary gland. Cancer Treatment and Research. 53: 47-78. PMID 1672090 DOI: 10.1007/978-1-4615-3940-7_3  0.72
1990 Barraclough R, Fernig DG, Rudland PS, Smith JA. Synthesis of basic fibroblast growth factor upon differentiation of rat mammary epithelial to myoepithelial-like cells in culture. Journal of Cellular Physiology. 144: 333-344. PMID 2166060 DOI: 10.1002/Jcp.1041440220  0.72
1990 Fernig DG, Smith JA, Rudland PS. Appearance of basic fibroblast growth factor receptors upon differentiation of rat mammary epithelial to myoepithelial-like cells in culture. Journal of Cellular Physiology. 142: 108-116. PMID 2153686 DOI: 10.1002/Jcp.1041420114  0.72
1990 Ke Y, Fernig DG, Smith JA, Wilkinson MC, Anandappa SY, Rudland PS, Barraclough R. High-level production of human acidic fibroblast growth factor in E. coli cells: inhibition of DNA synthesis in rat mammary fibroblasts at high concentrations of growth factor. Biochemical and Biophysical Research Communications. 171: 963-971. PMID 1699532 DOI: 10.1016/0006-291X(90)90778-L  0.72
1989 Smith JA, Barraclough R, Fernig DG, Rudland PS. Identification of alpha transforming growth factor as a possible local trophic agent for the mammary gland. Journal of Cellular Physiology. 141: 362-370. PMID 2808543 DOI: 10.1002/Jcp.1041410218  0.72
1987 Fernig DG, Mayer RJ. Degradation of nuclear proteins: studies on transplanted B82 cell karyoplast proteins Febs Letters. 210: 165-168. PMID 3025024 DOI: 10.1016/0014-5793(87)81329-7  0.64
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