Gong Chen - Publications

Biology Pennsylvania State University, State College, PA, United States 
Neurodevelopment and Neurodegeneration

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ma NX, Puls B, Chen G. Transcriptomic analyses of NeuroD1-mediated astrocyte-to-neuron conversion. Developmental Neurobiology. PMID 35606902 DOI: 10.1002/dneu.22882  0.324
2022 Wang T, Liao JC, Wang X, Wang QS, Wan KY, Yang YY, He Q, Zhang JX, Chen G, Li W. Unexpected BrdU inhibition on astrocyte-to-neuron conversion. Neural Regeneration Research. 17: 1526-1534. PMID 34916438 DOI: 10.4103/1673-5374.325747  0.331
2022 Zheng J, Li T, Qi S, Qin B, Yu J, Chen G. Neuroregenerative gene therapy to treat temporal lobe epilepsy in a rat model. Progress in Neurobiology. 208: 102198. PMID 34852273 DOI: 10.1016/j.pneurobio.2021.102198  0.318
2021 Tang Y, Wu Q, Gao M, Ryu E, Pei Z, Kissinger ST, Chen Y, Rao AK, Xiang Z, Wang T, Li W, Chen G, Chubykin AA. Restoration of Visual Function and Cortical Connectivity After Ischemic Injury Through NeuroD1-Mediated Gene Therapy. Frontiers in Cell and Developmental Biology. 9: 720078. PMID 34490268 DOI: 10.3389/fcell.2021.720078  0.663
2021 Wang H, Xu L, Lai C, Hou K, Chen J, Guo Y, Sambangi A, Swaminathan S, Xie C, Wu Z, Chen G. Region-specific distribution of Olig2-expressing astrocytes in adult mouse brain and spinal cord. Molecular Brain. 14: 36. PMID 33618751 DOI: 10.1186/s13041-021-00747-0  0.453
2021 Xiang Z, Xu L, Liu M, Wang Q, Li W, Lei W, Chen G. Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex. Neural Regeneration Research. 16: 750-756. PMID 33063738 DOI: 10.4103/1673-5374.295925  0.32
2020 Puls B, Ding Y, Zhang F, Pan M, Lei Z, Pei Z, Jiang M, Bai Y, Forsyth C, Metzger M, Rana T, Zhang L, Ding X, Keefe M, Cai A, ... ... Chen G, et al. Regeneration of Functional Neurons After Spinal Cord Injury via NeuroD1-Mediated Astrocyte-to-Neuron Conversion. Frontiers in Cell and Developmental Biology. 8: 591883. PMID 33425896 DOI: 10.3389/fcell.2020.591883  0.683
2020 Du J, Song XY, Shi XB, Tang X, Chen JB, Zhang ZH, Chen G, Zhang Z, Zhou XG, Liu Y, Zhang DY. NSs, the Silencing Suppressor of Tomato Spotted Wilt Orthotospovirus, Interferes With JA-Regulated Host Terpenoids Expression to Attract . Frontiers in Microbiology. 11: 590451. PMID 33362737 DOI: 10.3389/fmicb.2020.590451  0.33
2020 Zhang L, Lei Z, Guo Z, Pei Z, Chen Y, Zhang F, Cai A, Mok G, Lee G, Swaminathan V, Wang F, Bai Y, Chen G. Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue. Frontiers in Cellular Neuroscience. 14: 594170. PMID 33250718 DOI: 10.3389/fncel.2020.594170  0.805
2020 Ge LJ, Yang FH, Li W, Wang T, Lin Y, Feng J, Chen NH, Jiang M, Wang JH, Hu XT, Chen G. Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates. Frontiers in Cell and Developmental Biology. 8: 590008. PMID 33224952 DOI: 10.3389/fcell.2020.590008  0.741
2020 Wu Z, Parry M, Hou XY, Liu MH, Wang H, Cain R, Pei ZF, Chen YC, Guo ZY, Abhijeet S, Chen G. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nature Communications. 11: 1105. PMID 32107381 DOI: 10.1038/S41467-020-14855-3  0.768
2020 Chen J, Dong B, Feng X, Jiang D, Chen G, Long C, Yang L. Aberrant mPFC GABAergic Synaptic Transmission and Fear Behavior in Neuroligin-2 R215H Knock-in Mice. Brain Research. 146671. PMID 31953212 DOI: 10.1016/j.brainres.2020.146671  0.608
2020 Liu MH, Li W, Zheng JJ, Xu YG, He Q, Chen G. Differential neuronal reprogramming induced by NeuroD1 from astrocytes in grey matter white matter. Neural Regeneration Research. 15: 342-351. PMID 31552908 DOI: 10.4103/1673-5374.265185  0.342
2019 Chen YC, Ma NX, Pei ZF, Wu Z, Do-Monte FH, Keefe S, Yellin E, Chen MS, Yin JC, Lee G, Minier-Toribio A, Hu Y, Bai YT, Lee K, Quirk GJ, ... Chen G, et al. A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In Vivo Astrocyte-to-Neuron Conversion. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31551137 DOI: 10.1016/J.Ymthe.2019.09.003  0.792
2019 Ma NX, Yin JC, Chen G. Transcriptome Analysis of Small Molecule-Mediated Astrocyte-to-Neuron Reprogramming. Frontiers in Cell and Developmental Biology. 7: 82. PMID 31231645 DOI: 10.3389/Fcell.2019.00082  0.751
2019 Wu Z, Huo Q, Ren L, Dong F, Feng M, Wang Y, Bai Y, Lüscher B, Li ST, Wang GL, Long C, Wang Y, Wu G, Chen G. Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels. Molecular Brain. 12: 50. PMID 31088565 DOI: 10.1186/S13041-019-0465-0  0.737
2019 Yin JC, Zhang L, Ma NX, Wang Y, Lee G, Hou XY, Lei ZF, Zhang FY, Dong FP, Wu GY, Chen G. Chemical Conversion of Human Fetal Astrocytes into Neurons through Modulation of Multiple Signaling Pathways. Stem Cell Reports. PMID 30745031 DOI: 10.1016/J.Stemcr.2019.01.003  0.774
2019 Zhou L, Tang X, Li X, Bai Y, Buxbaum JN, Chen G. Identification of transthyretin as a novel interacting partner for the δ subunit of GABAA receptors. Plos One. 14: e0210094. PMID 30615651 DOI: 10.1371/Journal.Pone.0210094  0.559
2018 Jiang DY, Wu Z, Forsyth CT, Hu Y, Yee SP, Chen G. GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation. Molecular Brain. 11: 31. PMID 29859117 DOI: 10.1186/S13041-018-0375-6  0.413
2017 Wang Y, Wu Z, Bai YT, Wu GY, Chen G. Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 12: 73. PMID 29017573 DOI: 10.1186/S13024-017-0213-9  0.418
2016 Kilpatrick CL, Murakami S, Feng M, Wu X, Lal R, Chen G, Du K, Luscher B. Dissociation of Golgi-Associated DHHC-Type Zinc Finger Protein (GODZ) and Sertoli Cell Gene with a Zinc Finger Domain-β (SERZ-β)-Mediated Palmitoylation by Loss of Function Analyses in Knockout Mice. The Journal of Biological Chemistry. PMID 27875292 DOI: 10.1074/Jbc.M116.732768  0.477
2016 Yu M, Fang Y, Wang Z, Chen G, Pan Y, Yang X, Yin M, Yang Y, Li M, Cai Y, Huang R. Encapsulation layer design and scalability in encapsulated vertical 3D RRAM. Nanotechnology. 27: 205202. PMID 27044065 DOI: 10.1088/0957-4484/27/20/205202  0.311
2016 Wang B, Liu Y, Jiao R, Feng Y, Li Q, Chen C, Liu L, He G, Chen G. Total Synthesis of Mannopeptimycins α and β. Journal of the American Chemical Society. PMID 26914640 DOI: 10.1021/jacs.6b01384  0.335
2016 Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733678 DOI: 10.1073/Pnas.1524013113  0.705
2015 Zhang L, Yin JC, Yeh H, Ma NX, Lee G, Chen XA, Wang Y, Lin L, Chen L, Jin P, Wu GY, Chen G. Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons. Cell Stem Cell. PMID 26481520 DOI: 10.1016/J.Stem.2015.09.012  0.8
2015 Wu Z, Foster AC, Staubli U, Wu X, Sun C, Tang X, Li YX, Chen G. Effects of 3-aminoglutarate, a "silent" false transmitter for glutamate neurons, on synaptic transmission and epileptiform activity. Neuropharmacology. 97: 95-103. PMID 26002626 DOI: 10.1016/J.Neuropharm.2015.05.011  0.783
2015 Dong R, Chen G, Zheng S, Xia HH. Hepatic expression of interleukin 8 in diagnosing biliary atresia. Hepatology (Baltimore, Md.). 61: 731-2. PMID 24841829 DOI: 10.1002/hep.27229  0.376
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Chen G, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/Nature13716  0.716
2014 Wu Z, Guo Z, Gearing M, Chen G. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's [corrected] disease model. Nature Communications. 5: 4159. PMID 24923909 DOI: 10.1038/Ncomms5159  0.721
2014 Guo Z, Zhang L, Wu Z, Chen Y, Wang F, Chen G. In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model. Cell Stem Cell. 14: 188-202. PMID 24360883 DOI: 10.1016/J.Stem.2013.12.001  0.809
2013 Wang R, McGrath BC, Kopp RF, Roe MW, Tang X, Chen G, Cavener DR. Insulin secretion and Ca2+ dynamics in β-cells are regulated by PERK (EIF2AK3) in concert with calcineurin. The Journal of Biological Chemistry. 288: 33824-36. PMID 24114838 DOI: 10.1074/Jbc.M113.503664  0.355
2013 Wu X, Huang L, Wu Z, Zhang C, Jiang D, Bai Y, Wang Y, Chen G. Homeostatic competition between phasic and tonic inhibition. The Journal of Biological Chemistry. 288: 25053-65. PMID 23839941 DOI: 10.1074/Jbc.M113.491464  0.728
2013 Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Research. 11: 743-57. PMID 23759711 DOI: 10.1016/J.Scr.2013.05.002  0.65
2013 Sun C, Zhang L, Chen G. An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch. Molecular Brain. 6: 23. PMID 23663753 DOI: 10.1186/1756-6606-6-23  0.797
2013 Sun Y, Wu Z, Kong S, Jiang D, Pitre A, Wang Y, Chen G. Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors. Molecular Brain. 6: 21. PMID 23634821 DOI: 10.1186/1756-6606-6-21  0.793
2012 Guo W, Wu Z, Qiu Y, Chen G, Zheng X. The timing of sexual debut among Chinese youth. International Perspectives On Sexual and Reproductive Health. 38: 196-204. PMID 23318169 DOI: 10.1363/3819612  0.321
2012 Wu X, Wu Z, Ning G, Guo Y, Ali R, Macdonald RL, De Blas AL, Luscher B, Chen G. γ-Aminobutyric acid type A (GABAA) receptor α subunits play a direct role in synaptic versus extrasynaptic targeting. The Journal of Biological Chemistry. 287: 27417-30. PMID 22711532 DOI: 10.1074/Jbc.M112.360461  0.583
2012 Cichon J, Sun C, Chen B, Jiang M, Chen XA, Sun Y, Wang Y, Chen G. Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons. The Journal of Biological Chemistry. 287: 3919-29. PMID 22184127 DOI: 10.1074/Jbc.M111.301911  0.782
2011 Fan Y, Tang X, Vitriol E, Chen G, Zheng JQ. Actin capping protein is required for dendritic spine development and synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10228-33. PMID 21752999 DOI: 10.1523/Jneurosci.0115-11.2011  0.479
2011 Sun C, Cheng MC, Qin R, Liao DL, Chen TT, Koong FJ, Chen G, Chen CH. Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia. Human Molecular Genetics. 20: 3042-51. PMID 21551456 DOI: 10.1093/Hmg/Ddr208  0.76
2011 Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH. Modelling schizophrenia using human induced pluripotent stem cells. Nature. 473: 221-5. PMID 21490598 DOI: 10.1038/Nature09915  0.503
2010 Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 143: 527-39. PMID 21074045 DOI: 10.1016/J.Cell.2010.10.016  0.468
2010 Gu J, Lee CW, Fan Y, Komlos D, Tang X, Sun C, Yu K, Hartzell HC, Chen G, Bamburg JR, Zheng JQ. ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity. Nature Neuroscience. 13: 1208-15. PMID 20835250 DOI: 10.1038/Nn.2634  0.786
2010 Feng Y, Wang Y, Landgraf B, Liu S, Chen G. Facile benzo-ring construction via palladium-catalyzed functionalization of unactivated sp3 C-H bonds under mild reaction conditions. Organic Letters. 12: 3414-7. PMID 20583778 DOI: 10.1021/ol101220x  0.347
2010 Feng Y, Chen G. Total synthesis of celogentin C by stereoselective C-H activation. Angewandte Chemie (International Ed. in English). 49: 958-61. PMID 20029862 DOI: 10.1002/Anie.200905134  0.369
2009 Han X, Wu X, Chung WY, Li T, Nekrutenko A, Altman NS, Chen G, Ma H. Transcriptome of embryonic and neonatal mouse cortex by high-throughput RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 106: 12741-6. PMID 19617558 DOI: 10.1073/Pnas.0902417106  0.362
2009 Jiang M, Chen G. Ca2+ regulation of dynamin-independent endocytosis in cortical astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8063-74. PMID 19553446 DOI: 10.1523/JNEUROSCI.6139-08.2009  0.382
2009 Wang Y, Qi JS, Kong S, Sun Y, Fan J, Jiang M, Chen G. BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide. Neuropharmacology. 57: 49-59. PMID 19393251 DOI: 10.1016/j.neuropharm.2009.04.007  0.461
2008 Yuan X, Yao J, Norris D, Tran DD, Bram RJ, Chen G, Luscher B. Calcium-modulating cyclophilin ligand regulates membrane trafficking of postsynaptic GABA(A) receptors. Molecular and Cellular Neurosciences. 38: 277-89. PMID 18424167 DOI: 10.1016/J.Mcn.2008.03.002  0.424
2007 Chen G, Wu X, Tuncdemir S. Cell adhesion and synaptogenesis. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 59: 697-706. PMID 18157464  0.794
2007 Yu W, Jiang M, Miralles CP, Li RW, Chen G, de Blas AL. Gephyrin clustering is required for the stability of GABAergic synapses. Molecular and Cellular Neurosciences. 36: 484-500. PMID 17916433 DOI: 10.1016/j.mcn.2007.08.008  0.417
2007 Deng L, Yao J, Fang C, Dong N, Luscher B, Chen G. Sequential postsynaptic maturation governs the temporal order of GABAergic and glutamatergic synaptogenesis in rat embryonic cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10860-9. PMID 17913919 DOI: 10.1523/Jneurosci.2744-07.2007  0.826
2007 Dong N, Qi J, Chen G. Molecular reconstitution of functional GABAergic synapses with expression of neuroligin-2 and GABAA receptors. Molecular and Cellular Neurosciences. 35: 14-23. PMID 17336090 DOI: 10.1016/J.Mcn.2007.01.013  0.528
2006 Jiang M, Chen G. High Ca2+-phosphate transfection efficiency in low-density neuronal cultures. Nature Protocols. 1: 695-700. PMID 17406298 DOI: 10.1038/nprot.2006.86  0.381
2006 Fang C, Deng L, Keller CA, Fukata M, Fukata Y, Chen G, Lüscher B. GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12758-68. PMID 17151279 DOI: 10.1523/Jneurosci.4214-06.2006  0.771
2006 Qi JS, Yao J, Fang C, Luscher B, Chen G. Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures. The Journal of Physiology. 577: 579-90. PMID 16990405 DOI: 10.1113/Jphysiol.2006.113134  0.486
2006 Yao J, Qi J, Chen G. Actin-dependent activation of presynaptic silent synapses contributes to long-term synaptic plasticity in developing hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8137-47. PMID 16885227 DOI: 10.1523/Jneurosci.1183-06.2006  0.526
2006 Qi J, Wang Y, Jiang M, Warren P, Chen G. Cyclothiazide induces robust epileptiform activity in rat hippocampal neurons both in vitro and in vivo. The Journal of Physiology. 571: 605-18. PMID 16423850 DOI: 10.1113/jphysiol.2005.103812  0.493
2005 Zhou J, Pfaff DW, Chen G. Sex differences in estrogenic regulation of neuronal activity in neonatal cultures of ventromedial nucleus of the hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 102: 14907-12. PMID 16204378 DOI: 10.1073/pnas.0507440102  0.457
2004 Cao YQ, Piedras-Rentería ES, Smith GB, Chen G, Harata NC, Tsien RW. Presynaptic Ca2+ channels compete for channel type-preferring slots in altered neurotransmission arising from Ca2+ channelopathy. Neuron. 43: 387-400. PMID 15294146 DOI: 10.1016/J.Neuron.2004.07.014  0.748
2004 Chen G, Harata NC, Tsien RW. Paired-pulse depression of unitary quantal amplitude at single hippocampal synapses. Proceedings of the National Academy of Sciences of the United States of America. 101: 1063-8. PMID 14722357 DOI: 10.1073/pnas.0307149101  0.71
2003 Deng L, Chen G. Cyclothiazide potently inhibits gamma-aminobutyric acid type A receptors in addition to enhancing glutamate responses. Proceedings of the National Academy of Sciences of the United States of America. 100: 13025-9. PMID 14534329 DOI: 10.1073/pnas.2133370100  0.754
2003 Chen Y, Deng L, Maeno-Hikichi Y, Lai M, Chang S, Chen G, Zhang JF. Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis. Cell. 115: 37-48. PMID 14532001 DOI: 10.1016/S0092-8674(03)00726-8  0.743
1996 van den Pol AN, Obrietan K, Chen G, B. Belousov A. Neuropeptide Y-Mediated Long-Term Depression of Excitatory Activity in Suprachiasmatic Nucleus Neurons The Journal of Neuroscience. 16: 5883-5895. DOI: 10.1523/JNEUROSCI.16-18-05883.1996  0.602
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