| Year |
Citation |
Score |
| 2023 |
Chan WKB, Carlson HA, Traynor JR. . Molecular Pharmacology. PMID 36868791 DOI: 10.1124/molpharm.122.000612 |
0.685 |
|
| 2022 |
Chan WKB, Olson KM, Wotring JW, Sexton JZ, Carlson HA, Traynor JR. In silico analysis of SARS-CoV-2 proteins as targets for clinically available drugs. Scientific Reports. 12: 5320. PMID 35351926 DOI: 10.1038/s41598-022-08320-y |
0.539 |
|
| 2022 |
DasGupta D, Chan WKB, Carlson HA. Computational Identification of Possible Allosteric Sites and Modulators of the SARS-CoV-2 Main Protease. Journal of Chemical Information and Modeling. PMID 35107014 DOI: 10.1021/acs.jcim.1c01223 |
0.605 |
|
| 2021 |
Chan WKB, DasGupta D, Carlson HA, Traynor JR. Mixed-solvent molecular dynamics simulation-based discovery of a putative allosteric site on regulator of G protein signaling 4. Journal of Computational Chemistry. PMID 34494289 DOI: 10.1002/jcc.26747 |
0.703 |
|
| 2021 |
Liu Y, Hur J, Chan WKB, Wang Z, Xie J, Sun D, Handelman S, Sexton J, Yu H, He Y. Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection. Scientific Data. 8: 16. PMID 33441564 DOI: 10.1038/s41597-021-00799-w |
0.362 |
|
| 2020 |
Chan WKB, Zhang Y. Ligand-Profile Based Virtual Screening of Human GPCRs. Journal of Molecular Biology. PMID 32652079 DOI: 10.1016/J.Jmb.2020.07.003 |
0.417 |
|
| 2020 |
Chan W, Carlson H, Traynor J. Cosolvent Molecular Dynamics Simulation‐Based Discovery of Potential Allosteric Sites on Regulator of G Protein Signaling 4 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07054 |
0.675 |
|
| 2019 |
Wu J, Liu B, Chan WKB, Wu W, Pang T, Hu H, Yan S, Ke X, Zhang Y. Precise modelling and interpretation of bioactivities of ligands targeting G protein-coupled receptors. Bioinformatics (Oxford, England). 35: i324-i332. PMID 31510691 DOI: 10.1093/Bioinformatics/Btz336 |
0.442 |
|
| 2018 |
Wu J, Zhang Q, Wu W, Pang T, Hu H, Chan WKB, Ke X, Zhang Y, Wren J. WDL-RF: Predicting Bioactivities of Ligand Molecules Acting with G Protein-coupled Receptors by Combining Weighted Deep Learning and Random Forest. Bioinformatics (Oxford, England). PMID 29432522 DOI: 10.1093/Bioinformatics/Bty070 |
0.409 |
|
| 2015 |
Chan WK, Zhang H, Yang J, Brender JR, Hur J, Özgür A, Zhang Y. GLASS: a comprehensive database for experimentally validated GPCR-ligand associations. Bioinformatics (Oxford, England). PMID 25971743 DOI: 10.1093/Bioinformatics/Btv302 |
0.675 |
|
| 2012 |
Chan WK, Chen VP, Luk WK, Choi RC, Tsim KW. N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase. Neuroscience Letters. 523: 71-5. PMID 22750213 DOI: 10.1016/j.neulet.2012.06.045 |
0.517 |
|
| 2011 |
Chen VP, Luk WK, Chan WK, Leung KW, Guo AJ, Chan GK, Xu SL, Choi RC, Tsim KW. Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation. Frontiers in Molecular Neuroscience. 4: 36. PMID 22046147 DOI: 10.3389/fnmol.2011.00036 |
0.472 |
|
| 2011 |
Chen VP, Choi RC, Chan WK, Leung KW, Guo AJ, Chan GK, Luk WK, Tsim KW. The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization. The Journal of Biological Chemistry. 286: 32948-61. PMID 21795704 DOI: 10.1074/jbc.M111.261248 |
0.483 |
|
| 2010 |
Chen VP, Xie HQ, Chan WK, Leung KW, Chan GK, Choi RC, Bon S, Massoulié J, Tsim KW. The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain. The Journal of Biological Chemistry. 285: 27265-78. PMID 20566626 DOI: 10.1074/jbc.M110.113647 |
0.481 |
|
| 2010 |
Xie HQ, Leung KW, Chen VP, Chan GK, Xu SL, Guo AJ, Zhu KY, Zheng KY, Bi CW, Zhan JY, Chan WK, Choi RC, Tsim KW. PRiMA directs a restricted localization of tetrameric AChE at synapses. Chemico-Biological Interactions. 187: 78-83. PMID 20178777 DOI: 10.1016/j.cbi.2010.02.018 |
0.489 |
|
| 2010 |
Chen VP, Xie HQ, Chan WK, Leung KW, Choi RC, Tsim KW. An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells. Chemico-Biological Interactions. 187: 106-9. PMID 20176004 DOI: 10.1016/j.cbi.2010.02.024 |
0.447 |
|
| 2010 |
Xie HQ, Liang D, Leung KW, Chen VP, Zhu KY, Chan WK, Choi RC, Massoulié J, Tsim KW. Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. The Journal of Biological Chemistry. 285: 11537-46. PMID 20147288 DOI: 10.1074/jbc.M109.038711 |
0.492 |
|
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