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Katharina Hayer - Publications

Affiliations: 
2016- Biomedical and Health Informatics Children’s Hospital of Philadelphia / University of Pennsylvania, Philadelphia, PA, United States 
Area:
Bioinformatics, Computational Biology
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ang Z, Paruzzo L, Hayer KE, Schmidt C, Torres-Diz M, Xu F, Zankharia U, Zhang Y, Soldan SS, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, King Sainos P, et al. Alternative splicing of its 5' UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. Blood. PMID 37683180 DOI: 10.1182/blood.2023020400  0.662
2023 Ang Z, Paruzzo L, Hayer KE, Schmidt C, Torres Diz M, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, King Sainos P, et al. Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. Biorxiv : the Preprint Server For Biology. PMID 37645778 DOI: 10.1101/2023.02.19.529123  0.662
2022 Closa A, Reixachs-Solé M, Fuentes-Fayos AC, Hayer KE, Melero JL, Adriaanse FRS, Bos RS, Torres-Diz M, Hunger SP, Roberts KG, Mullighan CG, Stam RW, Thomas-Tikhonenko A, Castaño JP, Luque RM, et al. A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1. Nar Cancer. 4: zcac041. PMID 36518527 DOI: 10.1093/narcan/zcac041  0.647
2022 Yang SY, Hayer KE, Fazelinia H, Spruce LA, Asnani M, Black KL, Naqvi AS, Pillai V, Barash Y, Elenitoba-Johnson KSJ, Thomas-Tikhonenko A. FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells. Blood Advances. PMID 36322817 DOI: 10.1182/bloodadvances.2022007910  0.663
2022 Heard A, Landmann JH, Hansen AR, Papadopolou A, Hsu YS, Selli ME, Warrington JM, Lattin J, Chang J, Ha H, Haug-Kroeper M, Doray B, Gill S, Ruella M, Hayer KE, et al. Antigen glycosylation regulates efficacy of CAR T cells targeting CD19. Nature Communications. 13: 3367. PMID 35690611 DOI: 10.1038/s41467-022-31035-7  0.399
2021 Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallières M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, et al. Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies. Blood Cancer Discovery. PMID 35015683 DOI: 10.1158/2643-3230.BCD-21-0087  0.653
2021 Sehgal P, Lanauze C, Wang X, Hayer KE, Torres-Diz M, Leu NA, Sela Y, Stanger BZ, Lengner CJ, Thomas-Tikhonenko A. MYC hyperactivates WNT signaling in APC/CTNNB1-mutated colorectal cancer cells through miR-92a-dependent repression of DKK3. Molecular Cancer Research : McR. PMID 34593610 DOI: 10.1158/1541-7786.MCR-21-0666  0.571
2021 Schulz L, Torres-Diz M, Cortés-López M, Hayer KE, Asnani M, Tasian SK, Barash Y, Sotillo E, Zarnack K, König J, Thomas-Tikhonenko A. Direct long-read RNA sequencing identifies a subset of questionable exitrons likely arising from reverse transcription artifacts. Genome Biology. 22: 190. PMID 34183059 DOI: 10.1186/s13059-021-02411-1  0.627
2021 Lanauze CB, Sehgal P, Hayer K, Torres-Diz M, Pippin JA, Grant SFA, Thomas-Tikhonenko A. Colorectal cancer-associated Smad4 R361 hotspot mutations boost Wnt/β-catenin signaling through enhanced Smad4-LEF1 binding. Molecular Cancer Research : McR. PMID 33608451 DOI: 10.1158/1541-7786.MCR-20-0721  0.572
2019 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Correction: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia. PMID 31758088 DOI: 10.1038/S41375-019-0650-2  0.67
2019 Asnani M, Hayer KE, Naqvi AS, Zheng S, Yang SY, Oldridge D, Ibrahim F, Maragkakis M, Gazzara MR, Black KL, Bagashev A, Taylor D, Mourelatos Z, Grupp SA, Barrett D, et al. Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19. Leukemia. PMID 31591467 DOI: 10.1038/S41375-019-0580-Z  0.669
2019 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia. PMID 30914792 DOI: 10.1038/s41375-019-0454-4  0.679
2019 Zheng S, Naqvi AS, Bolton-Gillespie E, Asnani M, Hayer K, Barash Y, Thomas-Tikhonenko A. Pipeline for Discovering Neoepitopes Generated By Alternative Splicing in B-ALL Blood. 134: 1342-1342. DOI: 10.1182/Blood-2019-131277  0.712
2019 Li L, Hayer K, Xian L, Luo L, Cope L, Thomas-Tikhonenko A, Resar L. High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL Blood. 134: 3946-3946. DOI: 10.1182/Blood-2019-130261  0.671
2018 Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A. Aberrant splicing in B-cell acute lymphoblastic leukemia. Nucleic Acids Research. PMID 30517739 DOI: 10.1093/nar/gky1231  0.628
2018 Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A. Aberrant splicing in B-cell acute lymphoblastic leukemia. Nucleic Acids Research. PMID 30357359 DOI: 10.1093/Nar/Gky946  0.714
2018 Singh N, Shestova O, Hayer K, Hong A, Ravikumar P, Hoshino A, Shalem O, Weitzman MD, June CH, Gill SI, Ruella M. CAR T Cell Cytotoxicity Is Dependent on Death Receptor-Driven Apoptosis Blood. 132: 698-698. DOI: 10.1182/Blood-2018-99-117328  0.441
2014 Lahens NF, Kavakli IH, Zhang R, Hayer K, Black MB, Dueck H, Pizarro A, Kim J, Irizarry R, Thomas RS, Grant GR, Hogenesch JB. IVT-seq reveals extreme bias in RNA sequencing. Genome Biology. 15: R86. PMID 24981968 DOI: 10.1186/Gb-2014-15-6-R86  0.326
2014 Hayer K, Pizarro A, Hogenesch J, Grant GR. Benchmark analysis of algorithms for determining expressed full length mRNA splice forms from RNA-Seq data F1000research. 5. DOI: 10.7490/F1000Research.1095381.1  0.305
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