Paul Bornstein, M.D. - Publications

Affiliations: 
2007 Biochemistry University of Washington, Seattle, Seattle, WA 
Area:
collagen structure and synthesis, matricellular protein biochemistry
Website:
http://www.sfbmec.fr/?p=1485

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Huang Z, Newcomb CJ, Lei Y, Zhou Y, Bornstein P, Amendt BA, Stupp SI, Snead ML. Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration. Biomaterials. 61: 216-28. PMID 26004236 DOI: 10.1016/J.Biomaterials.2015.05.035  0.385
2011 Schultz GS, Davidson JM, Kirsner RS, Bornstein P, Herman IM. Dynamic reciprocity in the wound microenvironment. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 19: 134-48. PMID 21362080 DOI: 10.1111/J.1524-475X.2011.00673.X  0.338
2010 Frolova EG, Pluskota E, Krukovets I, Burke T, Drumm C, Smith JD, Blech L, Febbraio M, Bornstein P, Plow EF, Stenina OI. Thrombospondin-4 regulates vascular inflammation and atherogenesis. Circulation Research. 107: 1313-25. PMID 20884877 DOI: 10.1161/Circresaha.110.232371  0.3
2010 Card L, Henderson N, Zhang Y, Bornstein P, Bradshaw AD. Expression in SPARC-null mice of collagen type I lacking the globular domain of the α1(I) N-propeptide results in abdominal hernias and loss of dermal collagen. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 559-64. PMID 20708079 DOI: 10.1016/J.Matbio.2010.08.002  0.436
2010 Bornstein P. Collagen: relatively invariant (helical) and variable (nonhelical) regions. Science (New York, N.Y.). 161: 592-3. PMID 17835678 DOI: 10.1126/Science.161.3841.592  0.358
2009 Bornstein P. Thrombospondins function as regulators of angiogenesis. Journal of Cell Communication and Signaling. 3: 189-200. PMID 19798599 DOI: 10.1007/S12079-009-0060-8  0.359
2009 Bornstein P. Matricellular proteins: an overview. Journal of Cell Communication and Signaling. 3: 163-5. PMID 19779848 DOI: 10.1007/S12079-009-0069-Z  0.363
2009 Kyriakides TR, Wulsin D, Skokos EA, Fleckman P, Pirrone A, Shipley JM, Senior RM, Bornstein P. Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 65-73. PMID 19379668 DOI: 10.1016/J.Matbio.2009.01.001  0.666
2009 MacLauchlan S, Skokos EA, Meznarich N, Zhu DH, Raoof S, Shipley JM, Senior RM, Bornstein P, Kyriakides TR. Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9. Journal of Leukocyte Biology. 85: 617-26. PMID 19141565 DOI: 10.1189/Jlb.1008588  0.797
2009 Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, Bornstein P, Kyriakides TR. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 57: 301-13. PMID 19029404 DOI: 10.1369/Jhc.2008.952689  0.811
2008 Gruber HE, Bornstein P, Sage EH, Ingram JA, Zinchenko N, Norton HJ, Hanley EN. Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc. Arthritis Research & Therapy. 10: R96. PMID 18718009 DOI: 10.1186/Ar2483  0.327
2008 Krady MM, Zeng J, Yu J, MacLauchlan S, Skokos EA, Tian W, Bornstein P, Sessa WC, Kyriakides TR. Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. The American Journal of Pathology. 173: 879-91. PMID 18688033 DOI: 10.2353/Ajpath.2008.080128  0.804
2008 Posey KL, Hankenson K, Veerisetty AC, Bornstein P, Lawler J, Hecht JT. Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen. The American Journal of Pathology. 172: 1664-74. PMID 18467703 DOI: 10.2353/Ajpath.2008.071094  0.642
2008 Posey KL, Hankenson K, Veerisetty AC, Bornstein P, Lawler J, Hecht JT. Skeletal abnormalities in quad-KO mice (TSP1, 3, 5, and Col 9) Matrix Biology. 27: 37. DOI: 10.1016/J.Matbio.2008.09.328  0.612
2007 Rentz TJ, Poobalarahi F, Bornstein P, Sage EH, Bradshaw AD. SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. The Journal of Biological Chemistry. 282: 22062-71. PMID 17522057 DOI: 10.1074/Jbc.M700167200  0.439
2007 Lamy L, Foussat A, Brown EJ, Bornstein P, Ticchioni M, Bernard A. Interactions between CD47 and thrombospondin reduce inflammation. Journal of Immunology (Baltimore, Md. : 1950). 178: 5930-9. PMID 17442977 DOI: 10.4049/Jimmunol.178.9.5930  0.301
2007 Daniel C, Amann K, Hohenstein B, Bornstein P, Hugo C. Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in experimental glomerulonephritis in mice. Journal of the American Society of Nephrology : Jasn. 18: 788-98. PMID 17287428 DOI: 10.1681/Asn.2006080873  0.432
2007 Greenaway J, Lawler J, Moorehead R, Bornstein P, Lamarre J, Petrik J. Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). Journal of Cellular Physiology. 210: 807-18. PMID 17154366 DOI: 10.1002/Jcp.20904  0.316
2006 Kopp HG, Hooper AT, Broekman MJ, Avecilla ST, Petit I, Luo M, Milde T, Ramos CA, Zhang F, Kopp T, Bornstein P, Jin DK, Marcus AJ, Rafii S. Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. The Journal of Clinical Investigation. 116: 3277-91. PMID 17143334 DOI: 10.1172/Jci29314  0.427
2006 Oganesian A, Au S, Horst JA, Holzhausen LC, Macy AJ, Pace JM, Bornstein P. The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function. The Journal of Biological Chemistry. 281: 38507-18. PMID 17018525 DOI: 10.1074/Jbc.M607536200  0.302
2006 Nishiwaki T, Yamaguchi T, Zhao C, Amano H, Hankenson KD, Bornstein P, Toyama Y, Matsuo K. Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 596-604. PMID 16598380 DOI: 10.1359/Jbmr.051216  0.635
2006 Hankenson KD, Ausk BJ, Bain SD, Bornstein P, Gross TS, Srinivasan S. Mice lacking thrombospondin 2 show an atypical pattern of endocortical and periosteal bone formation in response to mechanical loading. Bone. 38: 310-6. PMID 16290255 DOI: 10.1016/J.Bone.2005.08.027  0.607
2005 Fears CY, Grammer JR, Stewart JE, Annis DS, Mosher DF, Bornstein P, Gladson CL. Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model. Cancer Research. 65: 9338-46. PMID 16230396 DOI: 10.1158/0008-5472.Can-05-1560  0.404
2005 Chen J, Somanath PR, Razorenova O, Chen WS, Hay N, Bornstein P, Byzova TV. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nature Medicine. 11: 1188-96. PMID 16227992 DOI: 10.1038/Nm1307  0.368
2005 Kalas W, Yu JL, Milsom C, Rosenfeld J, Benezra R, Bornstein P, Rak J. Oncogenes and Angiogenesis: down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant ras. Cancer Research. 65: 8878-86. PMID 16204059 DOI: 10.1158/0008-5472.Can-05-1479  0.312
2005 Hankenson KD, James IE, Apone S, Stroup GB, Blake SM, Liang X, Lark MW, Bornstein P. Increased osteoblastogenesis and decreased bone resorption protect against ovariectomy-induced bone loss in thrombospondin-2-null mice. Matrix Biology : Journal of the International Society For Matrix Biology. 24: 362-70. PMID 15979292 DOI: 10.1016/J.Matbio.2005.05.008  0.611
2005 Agah A, Kyriakides TR, Bornstein P. Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice. The American Journal of Pathology. 167: 81-8. PMID 15972954 DOI: 10.1016/S0002-9440(10)62955-0  0.693
2005 Hankenson KD, Hormuzdi SG, Meganck JA, Bornstein P. Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties of bone and have accelerated development of the femoral head. Molecular and Cellular Biology. 25: 5599-606. PMID 15964815 DOI: 10.1128/Mcb.25.13.5599-5606.2005  0.645
2005 Puolakkainen PA, Bradshaw AD, Brekken RA, Reed MJ, Kyriakides T, Funk SE, Gooden MD, Vernon RB, Wight TN, Bornstein P, Sage EH. SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 571-81. PMID 15872050 DOI: 10.1369/Jhc.4A6425.2005  0.683
2005 Bornstein P, Agah A, Kyriakides T. Corrigendum to “The role of Thrombospondins 1 and 2 in the regulation of cell–matrix interaction, collagen fibril formation and the response to injury” The International Journal of Biochemistry & Cell Biology. 37: 239-240. DOI: 10.1016/J.Biocel.2004.05.015  0.591
2004 Kyriakides TR, Foster MJ, Keeney GE, Tsai A, Giachelli CM, Clark-Lewis I, Rollins BJ, Bornstein P. The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. The American Journal of Pathology. 165: 2157-66. PMID 15579457 DOI: 10.1016/S0002-9440(10)63265-8  0.624
2004 Schroen B, Heymans S, Sharma U, Blankesteijn WM, Pokharel S, Cleutjens JP, Porter JG, Evelo CT, Duisters R, van Leeuwen RE, Janssen BJ, Debets JJ, Smits JF, Daemen MJ, Crijns HJ, ... Bornstein P, et al. Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circulation Research. 95: 515-22. PMID 15284191 DOI: 10.1161/01.Res.0000141019.20332.3E  0.337
2004 Bornstein P, Agah A, Kyriakides TR. The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injury. The International Journal of Biochemistry & Cell Biology. 36: 1115-25. PMID 15094126 DOI: 10.1016/J.Biocel.2004.01.012  0.691
2004 Cursiefen C, Masli S, Ng TF, Dana MR, Bornstein P, Lawler J, Streilein JW. Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis. Investigative Ophthalmology & Visual Science. 45: 1117-24. PMID 15037577 DOI: 10.1167/Iovs.03-0940  0.351
2004 Agah A, Kyriakides TR, Letrondo N, Björkblom B, Bornstein P. Thrombospondin 2 levels are increased in aged mice: consequences for cutaneous wound healing and angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 539-47. PMID 14996433 DOI: 10.1016/J.Matbio.2003.09.004  0.65
2004 Rahkonen O, Su M, Hakovirta H, Koskivirta I, Hormuzdi SG, Vuorio E, Bornstein P, Penttinen R. Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture. Circulation Research. 94: 83-90. PMID 14630726 DOI: 10.1161/01.Res.0000108263.74520.15  0.38
2004 Kokenyesi R, Armstrong LC, Agah A, Artal R, Bornstein P. Thrombospondin 2 Deficiency in Pregnant Mice Results in Premature Softening of the Uterine Cervix Biology of Reproduction. 70: 385-390. PMID 14561659 DOI: 10.1095/Biolreprod.102.014704  0.386
2004 Kyriakides TR, Agah A, Hartzel T, Brooks PC, Bornstein P. MMP2-DEPENDENT PROTEOLYSIS OF EXTRACELLULAR MATRICES IN THROMBOSPONDIN 2-NULL MICE CONTRIBUTES TO A BLEEDING DIATHESIS Cardiovascular Pathology. 13: 80. DOI: 10.1016/J.Carpath.2004.03.237  0.656
2003 Kyriakides TR, Bornstein P. Matricellular proteins as modulators of wound healing and the foreign body response. Thrombosis and Haemostasis. 90: 986-92. PMID 14652628 DOI: 10.1160/Th03-06-0399  0.644
2003 Kyriakides TR, Rojnuckarin P, Reidy MA, Hankenson KD, Papayannopoulou T, Kaushansky K, Bornstein P. Megakaryocytes require thrombospondin-2 for normal platelet formation and function. Blood. 101: 3915-23. PMID 12732502 DOI: 10.1182/Blood.V101.10.3915  0.712
2003 Armstrong LC, Bornstein P. Thrombospondins 1 and 2 function as inhibitors of angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 63-71. PMID 12714043 DOI: 10.1016/S0945-053X(03)00005-2  0.335
2003 Puolakkainen P, Bradshaw AD, Kyriakides TR, Reed M, Brekken R, Wight T, Bornstein P, Ratner B, Sage EH. Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials. The American Journal of Pathology. 162: 627-35. PMID 12547720 DOI: 10.1016/S0002-9440(10)63856-4  0.655
2002 Bornstein P, Sage EH. Matricellular proteins: extracellular modulators of cell function. Current Opinion in Cell Biology. 14: 608-16. PMID 12231357 DOI: 10.1016/S0955-0674(02)00361-7  0.368
2002 Agah A, Kyriakides TR, Lawler J, Bornstein P. The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. The American Journal of Pathology. 161: 831-9. PMID 12213711 DOI: 10.1016/S0002-9440(10)64243-5  0.658
2002 Bornstein P. Cell-matrix interactions: the view from the outside. Methods in Cell Biology. 69: 7-11. PMID 12071010 DOI: 10.1016/S0091-679X(02)69003-X  0.333
2002 Armstrong LC, Björkblom B, Hankenson KD, Siadak AW, Stiles CE, Bornstein P. Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism. Molecular Biology of the Cell. 13: 1893-905. PMID 12058057 DOI: 10.1091/Mbc.E01-09-0066  0.613
2002 Bornstein P. The NH(2)-terminal propeptides of fibrillar collagens: highly conserved domains with poorly understood functions. Matrix Biology : Journal of the International Society For Matrix Biology. 21: 217-26. PMID 12009328 DOI: 10.1016/S0945-053X(02)00008-2  0.351
2002 Hankenson KD, Bornstein P. The secreted protein thrombospondin 2 is an autocrine inhibitor of marrow stromal cell proliferation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 415-25. PMID 11874233 DOI: 10.1359/Jbmr.2002.17.3.415  0.601
2002 Lange-Asschenfeldt B, Weninger W, Velasco P, Kyriakides TR, von Andrian UH, Bornstein P, Detmar M. Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood. 99: 538-45. PMID 11781236 DOI: 10.1182/Blood.V99.2.538  0.65
2002 Kyriakides TR, Cheung CY, Murthy N, Bornstein P, Stayton PS, Hoffman AS. pH-sensitive polymers that enhance intracellular drug delivery in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 78: 295-303. PMID 11772470 DOI: 10.1016/S0168-3659(01)00504-1  0.625
2002 Bornstein P, Walsh V, Tullis J, Stainbrook E, Bateman JF, Hormuzdi SG. The globular domain of the proalpha 1(I) N-propeptide is not required for secretion, processing by procollagen N-proteinase, or fibrillogenesis of type I collagen in mice. The Journal of Biological Chemistry. 277: 2605-13. PMID 11705995 DOI: 10.1074/Jbc.M106181200  0.398
2002 Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, Bornstein P. Design of “Smart” polymers that can ­direct intracellular drug delivery Polymers For Advanced Technologies. 13: 992-999. DOI: 10.1002/Pat.232  0.557
2002 Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, Bornstein P. Design of "smart" Polymers that can direct intracellular drug delivery Polymers For Advanced Technologies. 13: 992-999.  0.472
2001 Kyriakides TR, Zhu YH, Yang Z, Huynh G, Bornstein P. Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice American Journal of Pathology. 159: 1255-1262. PMID 11583953 DOI: 10.1016/S0002-9440(10)62512-6  0.69
2001 Kyriakides TR, Hartzel T, Huynh G, Bornstein P. Regulation of angiogenesis and matrix remodeling by localized, matrix-mediated antisense gene delivery Molecular Therapy. 3: 842-849. PMID 11407897 DOI: 10.1006/Mthe.2001.0336  0.603
2001 Hawighorst T, Velasco P, Streit M, Hong YK, Kyriakides TR, Brown LF, Bornstein P, Detmar M. Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. The Embo Journal. 20: 2631-40. PMID 11387198 DOI: 10.1093/Emboj/20.11.2631  0.607
2001 Yang Z, Strickland DK, Bornstein P. Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2. The Journal of Biological Chemistry. 276: 8403-8. PMID 11113133 DOI: 10.1074/Jbc.M008925200  0.429
2001 Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, Bornstein P. Bioinspired polymers that control intracellular drug delivery Biotechnology and Bioprocess Engineering. 6: 205-212. DOI: 10.1007/Bf02931981  0.556
2000 Bornstein P, Kyriakides TR, Yang Z, Armstrong LC, Birk DE. Thrombospondin 2 modulates collagen fibrillogenesis and angiogenesis Journal of Investigative Dermatology Symposium Proceedings. 5: 61-66. PMID 11147677 DOI: 10.1046/J.1087-0024.2000.00005.X  0.69
2000 Bornstein P, Armstrong LC, Hankenson KD, Kyriakides TR, Yang Z. Thrombospondin 2, a matricellular protein with diverse functions Matrix Biology. 19: 557-568. PMID 11102746 DOI: 10.1016/S0945-053X(00)00104-9  0.763
2000 Yang Z, Kyriakides TR, Bornstein P. Matricellular proteins as modulators of cell-matrix interactions: Adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2 Molecular Biology of the Cell. 11: 3353-3364. PMID 11029041 DOI: 10.1091/Mbc.11.10.3353  0.683
2000 Hankenson KD, Bain SD, Kyriakides TR, Smith EA, Goldstein SA, Bornstein P. Increased marrow-derived osteoprogenitor cells and endosteal bone formation in mice lacking thrombospondin 2 Journal of Bone and Mineral Research. 15: 851-862. PMID 10804014 DOI: 10.1359/Jbmr.2000.15.5.851  0.73
1999 Streit M, Riccardi L, Velasco P, Brown LF, Hawighorst T, Bornstein P, Detmar M. Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 14888-93. PMID 10611308 DOI: 10.1073/Pnas.96.26.14888  0.302
1999 Kyriakides TR, Tam JWY, Bornstein P. Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene Journal of Investigative Dermatology. 113: 782-787. PMID 10571734 DOI: 10.1046/J.1523-1747.1999.00755.X  0.656
1999 Hormuzdi SG, Strandjord TP, Madtes DK, Bornstein P. Mice with a targeted intronic deletion in the Col1a1 gene respond to bleomycin-induced pulmonary fibrosis with increased expression of the mutant allele. Matrix Biology : Journal of the International Society For Matrix Biology. 18: 287-94. PMID 10429947 DOI: 10.1016/S0945-053X(99)00017-7  0.365
1999 Kyriakides TR, Leach KJ, Hoffman AS, Ratner BD, Bornstein P. Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. Proceedings of the National Academy of Sciences of the United States of America. 96: 4449-54. PMID 10200282 DOI: 10.1073/Pnas.96.8.4449  0.671
1998 Kyriakides TR, Zhu YH, Yang Z, Bornstein P. The distribution of the matricellular protein thrombospondin 2 in tissues of embryonic and adult mice Journal of Histochemistry and Cytochemistry. 46: 1007-1015. PMID 9705966 DOI: 10.1177/002215549804600904  0.647
1998 Collins M, Rojnuckarin P, Zhu YH, Bornstein P. A far upstream, cell type-specific enhancer of the mouse thrombospondin 3 gene is located within intron 6 of the adjacent metaxin gene Journal of Biological Chemistry. 273: 21816-21824. PMID 9705320 DOI: 10.1074/Jbc.273.34.21816  0.336
1998 Hormuzdi SG, Penttinen R, Jaenisch R, Bornstein P. A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene. Molecular and Cellular Biology. 18: 3368-75. PMID 9584177 DOI: 10.1128/Mcb.18.6.3368  0.358
1996 Bornstein P. Regulation of expression of the alpha 1 (I) collagen gene: a critical appraisal of the role of the first intron. Matrix Biology : Journal of the International Society For Matrix Biology. 15: 3-10. PMID 8783182 DOI: 10.1016/S0945-053X(96)90121-3  0.335
1996 Iruela-Arispe ML, Porter P, Bornstein P, Sage EH. Thrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium. The Journal of Clinical Investigation. 97: 403-12. PMID 8567961 DOI: 10.1172/Jci118429  0.358
1995 Hugo C, Pichler R, Meek R, Gordon K, Kyriakides T, Floege J, Bornstein P, Couser WG, Johnson RJ. Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo Kidney International. 48: 1846-1856. PMID 8587244 DOI: 10.1038/Ki.1995.483  0.594
1995 Bornstein P, McKinney CE, LaMarca ME, Winfield S, Shingu T, Devarayalu S, Vos HL, Ginns EI. Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease. Proceedings of the National Academy of Sciences of the United States of America. 92: 4547-51. PMID 7753840 DOI: 10.1073/Pnas.92.10.4547  0.315
1994 Liska DJ, Reed MJ, Sage EH, Bornstein P. Cell-specific expression of α1(I) collagen-hGH minigenes in transgenic mice Journal of Cell Biology. 125: 695-704. PMID 8175887 DOI: 10.1083/Jcb.125.3.695  0.386
1994 Liska DJ, Hawkins R, Wikstrom K, Bornstein P. Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells. Journal of Cellular Physiology. 158: 495-505. PMID 8126073 DOI: 10.1002/Jcp.1041580314  0.323
1993 Bornstein P, Devarayalu S, Edelhoff S, Disteche CM. Isolation and characterization of the mouse thrombospondin 3 (Thbs3) gene. Genomics. 15: 607-13. PMID 8468055 DOI: 10.1006/Geno.1993.1114  0.32
1993 Slack JL, Liska DJ, Bornstein P. Regulation of expression of the type I collagen genes. American Journal of Medical Genetics. 45: 140-51. PMID 8456796 DOI: 10.1002/Ajmg.1320450203  0.32
1993 Reed MJ, Puolakkainen P, Lane TF, Dickerson D, Bornstein P, Sage EH. Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 1467-77. PMID 8245406 DOI: 10.1177/41.10.8245406  0.356
1992 Sherbina NV, Bornstein P. Modulation of thrombospondin gene expression during osteoblast differentiation in MC3T3-E1 cells. Bone. 13: 197-201. PMID 1576018 DOI: 10.1016/8756-3282(92)90012-L  0.344
1992 Bornstein P. Thrombospondins: structure and regulation of expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 3290-9. PMID 1426766 DOI: 10.1096/Fasebj.6.14.1426766  0.369
1991 Slack JL, Liska DJ, Bornstein P. An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice. Molecular and Cellular Biology. 11: 2066-74. PMID 2005897 DOI: 10.1128/Mcb.11.4.2066  0.349
1991 Fouser L, Sage EH, Clark J, Bornstein P. Feedback regulation of collagen gene expression: a Trojan horse approach. Proceedings of the National Academy of Sciences of the United States of America. 88: 10158-62. PMID 1946435 DOI: 10.1073/Pnas.88.22.10158  0.388
1991 Iruela-Arispe ML, Bornstein P, Sage H. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proceedings of the National Academy of Sciences of the United States of America. 88: 5026-30. PMID 1711216 DOI: 10.1073/Pnas.88.11.5026  0.336
1990 Donoviel DB, Amacher SL, Judge KW, Bornstein P. Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: Induction by basic fibroblast growth factor Journal of Cellular Physiology. 145: 16-23. PMID 2211838 DOI: 10.1002/Jcp.1041450104  0.329
1990 Sherwood AL, Bottenus RE, Martzen MR, Bornstein P. Structural and functional analysis of the first intron of the human alpha 2(I) collagen-encoding gene. Gene. 89: 239-44. PMID 2129528 DOI: 10.1016/0378-1119(90)90011-F  0.301
1990 Liska DJ, Slack JL, Bornstein P. A highly conserved intronic sequence is involved in transcriptional regulation of the alpha 1(I) collagen gene. Cell Regulation. 1: 487-98. PMID 2127540 DOI: 10.1091/Mbc.1.6.487  0.308
1989 Bornstein P, Sage H. Regulation of collagen gene expression. Progress in Nucleic Acid Research and Molecular Biology. 37: 67-106. PMID 2672111 DOI: 10.1016/S0079-6603(08)60695-9  0.423
1988 Penttinen RP, Kobayashi S, Bornstein P. Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proceedings of the National Academy of Sciences of the United States of America. 85: 1105-8. PMID 3422482 DOI: 10.1073/Pnas.85.4.1105  0.31
1988 Bornstein P, McKay J, Liska DJ, Apone S, Devarayalu S. Interactions between the promoter and first intron are involved in transcriptional control of alpha 1(I) collagen gene expression. Molecular and Cellular Biology. 8: 4851-7. PMID 3211130 DOI: 10.1128/Mcb.8.11.4851  0.339
1988 Bornstein P, McKay J, Devarayalu S, Cook SC. A highly conserved, 5' untranslated, inverted repeat sequence is ineffective in translational control of the alpha 1(I) collagen gene. Nucleic Acids Research. 16: 9721-36. PMID 3186444 DOI: 10.1093/Nar/16.20.9721  0.312
1988 Kapoor R, Sakai LY, Funk S, Roux E, Bornstein P, Sage EH. Type VIII collagen has a restricted distribution in specialized extracellular matrices. The Journal of Cell Biology. 107: 721-30. PMID 3047147 DOI: 10.1083/Jcb.107.2.721  0.393
1987 Bornstein P, McKay J, Morishima JK, Devarayalu S, Gelinas RE. Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 8869-73. PMID 3480516 DOI: 10.1073/Pnas.84.24.8869  0.308
1986 Kapoor R, Bornstein P, Sage EH. Type VIII collagen from bovine Descemet's membrane: structural characterization of a triple-helical domain. Biochemistry. 25: 3930-7. PMID 3527259 DOI: 10.1021/Bi00361A029  0.308
1986 Majack RA, Cook SC, Bornstein P. Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. Proceedings of the National Academy of Sciences of the United States of America. 83: 9050-4. PMID 3491367 DOI: 10.1073/Pnas.83.23.9050  0.367
1986 Voss T, Bornstein P. Regulation of type I collagen mRNA levels in fibroblasts. European Journal of Biochemistry. 157: 433-9. PMID 2872053 DOI: 10.1111/J.1432-1033.1986.Tb09686.X  0.327
1985 Majack RA, Cook SC, Bornstein P. Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells. The Journal of Cell Biology. 101: 1059-70. PMID 4030891 DOI: 10.1083/Jcb.101.3.1059  0.337
1985 Wight TN, Raugi GJ, Mumby SM, Bornstein P. Light microscopic immunolocation of thrombospondin in human tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 33: 295-302. PMID 3884704 DOI: 10.1177/33.4.3884704  0.322
1985 Majack RA, Bornstein P. Regulation of collagen biosynthesis. Heparin alters the biosynthetic phenotype of vascular smooth muscle cells. Annals of the New York Academy of Sciences. 460: 172-80. PMID 3868945 DOI: 10.1111/J.1749-6632.1985.Tb51165.X  0.316
1984 Mumby SM, Raugi GJ, Bornstein P. Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen. The Journal of Cell Biology. 98: 646-52. PMID 6693501 DOI: 10.1083/Jcb.98.2.646  0.393
1984 Majack RA, Bornstein P. Heparin and related glycosaminoglycans modulate the secretory phenotype of vascular smooth muscle cells. The Journal of Cell Biology. 99: 1688-95. PMID 6490716 DOI: 10.1083/Jcb.99.5.1688  0.319
1984 Mumby SM, Abbott-Brown D, Raugi GJ, Bornstein P. Regulation of thrombospondin secretion by cells in culture. Journal of Cellular Physiology. 120: 280-8. PMID 6086679 DOI: 10.1002/Jcp.1041200304  0.364
1983 Raugi GJ, Mumby SM, Abbott-Brown D, Bornstein P. Thrombospondin: synthesis and secretion by cells in culture. The Journal of Cell Biology. 95: 351-4. PMID 6754743 DOI: 10.1083/Jcb.95.1.351  0.328
1983 Sage H, Mecham R, Johnson C, Bornstein P. Fetal calf ligament fibroblasts in culture secrete a low molecular weight collagen with a unique resistance to proteolytic degradation. The Journal of Cell Biology. 97: 1933-8. PMID 6315746 DOI: 10.1083/Jcb.97.6.1933  0.361
1982 Sage H, Pritzl P, Bornstein P. Endothelial cells secrete a novel collagen type in vitro independently of prolyl hydroxylation. Collagen and Related Research. 2: 465-79. PMID 7168951 DOI: 10.1016/S0174-173X(82)80003-4  0.366
1982 Sage H, Bornstein P. Preparation and characterization of procollagens and procollagen-collagen intermediates. Methods in Enzymology. 82: 96-127. PMID 7078459 DOI: 10.1016/0076-6879(82)82061-2  0.349
1982 Oohira A, Wight TN, McPherson J, Bornstein P. Biochemical and ultrastructural studies of proteoheparan sulfates synthesized by PYS-2, a basement membrane-producing cell line. The Journal of Cell Biology. 92: 357-67. PMID 6174529 DOI: 10.1083/Jcb.92.2.357  0.345
1981 Sage H, Pritzl P, Bornstein P. A new mapping technique for collagen chains. Collagen and Related Research. 1: 3-15. PMID 7346220 DOI: 10.1016/S0174-173X(80)80003-3  0.314
1981 Sage H, Pritzl P, Bornstein P. Characterization of cell matrix associated collagens synthesized by aortic endothelial cells in culture. Biochemistry. 20: 436-42. PMID 7008844 DOI: 10.1021/Bi00505A032  0.375
1981 Hörlein D, McPherson J, Goh SH, Bornstein P. Regulation of protein synthesis: translational control by procollagen-derived fragments. Proceedings of the National Academy of Sciences of the United States of America. 78: 6163-7. PMID 6947219 DOI: 10.1073/Pnas.78.10.6163  0.306
1980 Cotta-Pereira G, Sage H, Bornstein P, Ross R, Schwartz S. Studies of morphologically atypical ("sprouting") cultures of bovine aortic endothelial cells. Growth characteristics and connective tissue protein synthesis. Journal of Cellular Physiology. 102: 183-91. PMID 7189521 DOI: 10.1002/Jcp.1041020209  0.344
1980 Crouch E, Sage H, Bornstein P. Structural basis for apparent heterogeneity of collagens in human basement membranes: type IV procollagen contains two distinct chains. Proceedings of the National Academy of Sciences of the United States of America. 77: 745-9. PMID 6987668 DOI: 10.1073/Pnas.77.2.745  0.357
1980 Sage H, Pritzl P, Bornstein P. A unique, pepsin-sensitive collagen synthesized by aortic endothelial cells in culture. Biochemistry. 19: 5747-55. PMID 6257289 DOI: 10.1021/Bi00566A013  0.361
1980 Byers PH, Siegel RC, Holbrook KA, Narayanan AS, Bornstein P, Hall JG. X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity. The New England Journal of Medicine. 303: 61-5. PMID 6104292 DOI: 10.1056/Nejm198007103030201  0.355
1979 Norwood TH, Pendergrass W, Bornstein P, Martin GM. DNA synthesis of sublethally injured cells in heterokaryons and its relevance to clonal senescence. Experimental Cell Research. 119: 15-21. PMID 761601 DOI: 10.1016/0014-4827(79)90330-6  0.302
1979 Balian G, Crouch E, Click EM, Carter WG, Bornstein P. Comparison of the structures of human fibronectin and plasma cold-insoluble globulin. Journal of Supramolecular Structure. 12: 505-16. PMID 550011 DOI: 10.1002/Jss.400120410  0.321
1979 Sage H, Crouch E, Bornstein P. Collagen synthesis by bovine aortic endothelial cells in culture. Biochemistry. 18: 5433-42. PMID 391267 DOI: 10.1021/Bi00591A028  0.411
1979 Davidson JM, McEneany LS, Bornstein P. Procollagen processing. Limited proteolysis of COOH-terminal extension peptides by a cathepsin-like protease secreted by tendon fibroblasts. European Journal of Biochemistry / Febs. 100: 551-8. PMID 41715 DOI: 10.1111/J.1432-1033.1979.Tb04201.X  0.318
1978 Crouch E, Balian G, Holbrook K, Duksin D, Bornstein P. Amniotic fluid fibronectin. Characterization and synthesis by cells in culture. The Journal of Cell Biology. 78: 701-15. PMID 701356 DOI: 10.1083/Jcb.78.3.701  0.347
1978 Duksin D, Holbrook K, Williams K, Bornstein P. Cell surface morphology and adhesive properties of normal and virally transformed cells treated with tunicamycin, an inhibitor of protein glycosylation. Experimental Cell Research. 116: 153-65. PMID 699989 DOI: 10.1016/0014-4827(78)90072-1  0.31
1978 Duksin D, Davidson JM, Bornstein P. The role of glycosylation in the enzymatic conversion of procollagen to collagen: studies using tunicamycin and concanavalin A. Archives of Biochemistry and Biophysics. 185: 326-32. PMID 564661 DOI: 10.1016/0003-9861(78)90174-1  0.354
1978 Byers PH, Holbrook KA, Hall JG, Bornstein P, Chandler JW. A new variety of spondyloepiphyseal dysplasia characterized by punctate corneal dystrophy and abnormal dermal collagen fibrils Human Genetics. 40: 157-169. PMID 414988 DOI: 10.1007/Bf00272296  0.335
1978 Bornstein P, Duksin D, Balian G, Davidson JM, Crouch E. Organization of extracellular proteins on the connective tissue cell surface: relevance to cell-matrix interactions in vitro and in vivo. Annals of the New York Academy of Sciences. 312: 93-105. PMID 386885 DOI: 10.1111/J.1749-6632.1978.Tb16795.X  0.376
1978 Crouch E, Bornstein P. Collagen synthesis by human amniotic fluid cells in culture: characterization of a procollagen with three identical proalpha1(I) chains. Biochemistry. 17: 5499-509. PMID 215203 DOI: 10.1021/Bi00618A027  0.362
1978 Kruse NJ, Rowe DW, Fujimoto WY, Bornstein P. Inhibitory effects of glucocorticoids on collagen synthesis by mouse sponge granulomas and granuloma fibroblasts in culture Bba - General Subjects. 540: 101-116. PMID 205274 DOI: 10.1016/0304-4165(78)90439-7  0.4
1977 Burke JM, Balian G, Ross R, Bornstein P. Synthesis of types I and III procollagen and collagen by monkey aortic smooth muscle cells in vitro. Biochemistry. 16: 3243-9. PMID 407926 DOI: 10.1021/Bi00633A031  0.363
1977 Bornstein P, Ash JF. Cell surface-associated structural proteins in connective tissue cells. Proceedings of the National Academy of Sciences of the United States of America. 74: 2480-4. PMID 329287 DOI: 10.1073/Pnas.74.6.2480  0.363
1977 Davidson JM, McEneany LS, Bornstein P. Intermediates in the conversion of procollagen to collagen. Evidence for stepwise limited proteolysis of the COOH-terminal peptide extensions. European Journal of Biochemistry / Febs. 81: 349-55. PMID 202456 DOI: 10.1111/J.1432-1033.1977.Tb11958.X  0.345
1977 Duksin D, Bornstein P. Changes in surface properties of normal and transformed cells caused by tunicamycin, an inhibitor of protein glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 74: 3433-7. PMID 198786 DOI: 10.1073/Pnas.74.8.3433  0.318
1976 Muir LW, Bornstein P, Ross R. A presumptive subunit of elastic fiber microfibrils secreted by arterial smooth-muscle cells in culture. European Journal of Biochemistry. 64: 105-14. PMID 819259 DOI: 10.1111/J.1432-1033.1976.Tb10278.X  0.322
1975 Ehrlich HP, Ross R, Bornstein P. Effects of antimicrotubular agents on the secretion of collagen. A biochemical and morphological study. The Journal of Cell Biology. 62: 390-405. PMID 4426914 DOI: 10.1083/Jcb.62.2.390  0.398
1975 Nist C, Von Der Mark K, Hay ED, Olsen BR, Bornstein P, Ross R, Dehm P. Location of procollagen in chick corneal and tendon fibroblasts with ferritin-conjugated antibodies. The Journal of Cell Biology. 65: 75-87. PMID 1168646 DOI: 10.1083/Jcb.65.1.75  0.306
1974 Jansen HW, Bornstein P. Effects of antimicrotubular agents on glycosaminoglycan synthesis and secretion by embryonic chick cartilage and chondrocytes Biochimica Et Biophysica Acta. 362: 150-159. PMID 4278546 DOI: 10.1016/0304-4165(74)90036-1  0.318
1973 Monson JM, Bornstein P. Identification of a Disulfide-Linked Procollagen as the Biosynthetic Precursor of Chick-Bone Collagen Proceedings of the National Academy of Sciences of the United States of America. 70: 3521-3525. PMID 4519643 DOI: 10.1073/Pnas.70.12.3521  0.314
1972 Clark CC, Bornstein P. Cyanogen bromide cleavage of guinea pig skin collagen. Isolation and characterization of peptides from the 1 and 2 chains. Biochemistry. 11: 1468-74. PMID 5021600 DOI: 10.1021/Bi00758A022  0.306
1972 Bornstein P, Ehrlich HP, Wyke AW. Procollagen: conversion of the precursor to collagen by a neutral protease. Science (New York, N.Y.). 175: 544-6. PMID 5008597 DOI: 10.1126/Science.175.4021.544  0.328
1972 Bellamy G, Bornstein P. Evidence for procollagen, a biosynthetic precursors of collagen. Proceedings of the National Academy of Sciences of the United States of America. 68: 1138-42. PMID 4942180 DOI: 10.1073/Pnas.68.6.1138  0.305
1972 Piez KA, Balian G, Click EM, Bornstein P. Homology between the 1 and 2 chains of collagen. Biochemical and Biophysical Research Communications. 48: 990-5. PMID 4636657 DOI: 10.1016/0006-291X(72)90706-1  0.574
1970 Bornstein P, Nesse R. The comparative biochemistry of collagen: the structure of rabbit skin colllagen and its relevance to immunochemical studies of collagen. Archives of Biochemistry and Biophysics. 138: 443-50. PMID 4194291 DOI: 10.1016/0003-9861(70)90367-X  0.326
1969 Bornstein P. Comparative sequence studies of rat skin and tendon collagen. II. The absence of a short sequence at the amino terminus of the skin alpha-1 chain. Biochemistry. 8: 63-71. PMID 5777344 DOI: 10.1021/Bi00829A010  0.303
1968 Bornstein P. Comparative sequence studies of rat skin and tendon collagen. I. Evidence for incomplete hydroxylation of individual prolyl residues in the normal proteins. Biochemistry. 6: 3082-93. PMID 4293540 DOI: 10.1021/Bi00862A015  0.326
1967 Butler WT, Piez KA, Bornstein P. Isolation and characterization of the cyanogen bromide peptides from the alpha-1 chain of rat skin collagen. Biochemistry. 6: 3771-80. PMID 5624602 DOI: 10.1021/Bi00864A022  0.588
1966 Bornstein P, Piez KA. The nature of the intramolecular cross-links in collagen. The separation and characterization of peptides from the cross-link region of rat skin collagen. Biochemistry. 5: 3460-73. PMID 5972327 DOI: 10.1021/Bi00875A012  0.602
1966 Bornstein P, Kang AH, Piez KA. The nature and location of intramolecular cross-links in collagen. Proceedings of the National Academy of Sciences of the United States of America. 55: 417-24. PMID 5220959 DOI: 10.1073/Pnas.55.2.417  0.589
1966 Piez KA, Martin GR, Kang AH, Bornstein P. Heterogeneity of the α Chains of Rat Skin Collagen and Its Relation to the Biosynthesis of Cross-Links* Biochemistry. 5: 3813-3820. DOI: 10.1021/Bi00876A011  0.551
1966 Bornstein P, Kang AH, Piez KA. The Limited Cleavage of Native Collagen with Chymotrypsin, Trypsin, and Cyanogen Bromide* Biochemistry. 5: 3803-3812. DOI: 10.1021/Bi00876A010  0.589
1964 BORNSTEIN P, PIEZ KA. A BIOCHEMICAL STUDY OF HUMAN SKIN COLLAGEN AND THE RELATION BETWEEN INTRA- AND INTERMOLECULAR CROSS-LINKING. The Journal of Clinical Investigation. 43: 1813-23. PMID 14207773 DOI: 10.1172/Jci105055  0.602
1964 Bakerman S, Bornstein P, Martin GR, Piez KA. Beta-Components In Collagen. Science. 145: 837-837. PMID 14163333 DOI: 10.1126/Science.145.3634.837  0.56
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