| Year |
Citation |
Score |
| 2023 |
Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DS, Li Z, DeBarge R, Spitzer MH, Marson A, Ansel KM. The lncRNA inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation. Elife. 12. PMID 38127070 DOI: 10.7554/eLife.87900 |
0.341 |
|
| 2023 |
Schmidt R, Ward CC, Dajani R, Armour-Garb Z, Ota M, Allain V, Hernandez R, Layeghi M, Xing G, Goudy L, Dorovskyi D, Wang C, Chen YY, Ye CJ, Shy BR, ... ... Marson A, et al. Base-editing mutagenesis maps alleles to tune human T cell functions. Nature. PMID 38093011 DOI: 10.1038/s41586-023-06835-6 |
0.429 |
|
| 2023 |
Andrabi SBA, Batkulwar K, Bhosale SD, Moulder R, Khan MH, Buchacher T, Khan MM, Arnkil I, Rasool O, Marson A, Kalim UU, Lahesmaa R. HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function. Immunology Letters. 263: 123-132. PMID 37838026 DOI: 10.1016/j.imlet.2023.09.001 |
0.353 |
|
| 2023 |
Weinstock JS, Arce MM, Freimer JW, Ota M, Marson A, Battle A, Pritchard JK. Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease. Biorxiv : the Preprint Server For Biology. PMID 37745614 DOI: 10.1101/2023.09.17.557749 |
0.307 |
|
| 2023 |
Blaeschke F, Chen YY, Apathy R, Daniel B, Chen AY, Chen PA, Sandor K, Zhang W, Li Z, Mowery CT, Yamamoto TN, Nyberg WA, To A, Yu R, Bueno R, ... ... Marson A, et al. Modular pooled discovery of synthetic knockin sequences to program durable cell therapies. Cell. 186: 4216-4234.e33. PMID 37714135 DOI: 10.1016/j.cell.2023.08.013 |
0.828 |
|
| 2023 |
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, ... ... Marson A, et al. CRISPR screens decode cancer cell pathways that trigger γδ T cell detection. Nature. PMID 37648854 DOI: 10.1038/s41586-023-06482-x |
0.454 |
|
| 2023 |
Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DS, Li Z, Debarge R, Spitzer M, Marson A, Ansel KM. The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation. Biorxiv : the Preprint Server For Biology. PMID 37547023 DOI: 10.1101/2023.04.14.536843 |
0.353 |
|
| 2023 |
Simeonov DR, Park K, Cortez JT, Young A, Li Z, Nguyen V, Umhoefer J, Indart AC, Woo JM, Anderson MS, Tsang JS, Germain RN, Wong HS, Marson A. Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease risk. Biorxiv : the Preprint Server For Biology. PMID 37503101 DOI: 10.1101/2023.06.17.545426 |
0.332 |
|
| 2023 |
Foss DV, Muldoon JJ, Nguyen DN, Carr D, Sahu SU, Hunsinger JM, Wyman SK, Krishnappa N, Mendonsa R, Schanzer EV, Shy BR, Vykunta VS, Allain V, Li Z, Marson A, et al. Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature Biomedical Engineering. PMID 37147433 DOI: 10.1038/s41551-023-01032-2 |
0.359 |
|
| 2023 |
Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature Immunology. PMID 36914891 DOI: 10.1038/s41590-023-01444-x |
0.398 |
|
| 2022 |
Goodman DB, Azimi CS, Kearns K, Talbot A, Garakani K, Garcia J, Patel N, Hwang B, Lee D, Park E, Vykunta VS, Shy BR, Ye CJ, Eyquem J, Marson A, et al. Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies. Science Translational Medicine. 14: eabm1463. PMID 36350984 DOI: 10.1126/scitranslmed.abm1463 |
0.757 |
|
| 2022 |
Bucktrout SL, Banovich NE, Butterfield LH, Cimen-Bozkus C, Giles JR, Good Z, Goodman D, Jonsson VD, Lareau C, Marson A, Maurer DM, Munson PV, Stubbington M, Taylor S, Cutchin A. Advancing T cell-based cancer therapy with single-cell technologies. Nature Medicine. 28: 1761-1764. PMID 36127419 DOI: 10.1038/s41591-022-01986-x |
0.689 |
|
| 2022 |
Shy BR, Vykunta VS, Ha A, Talbot A, Roth TL, Nguyen DN, Pfeifer WG, Chen YY, Blaeschke F, Shifrut E, Vedova S, Mamedov MR, Chung JJ, Li H, Yu R, ... ... Marson A, et al. High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails. Nature Biotechnology. PMID 36008610 DOI: 10.1038/s41587-022-01418-8 |
0.728 |
|
| 2022 |
Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, ... ... Marson A, et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature. PMID 36002574 DOI: 10.1038/s41586-022-05126-w |
0.832 |
|
| 2022 |
Belk JA, Yao W, Ly N, Freitas KA, Chen YT, Shi Q, Valencia AM, Shifrut E, Kale N, Yost KE, Duffy CV, Daniel B, Hwee MA, Miao Z, Ashworth A, ... ... Marson A, et al. Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence. Cancer Cell. PMID 35750052 DOI: 10.1016/j.ccell.2022.06.001 |
0.449 |
|
| 2022 |
Hiatt J, Hultquist JF, McGregor MJ, Bouhaddou M, Leenay RT, Simons LM, Young JM, Haas P, Roth TL, Tobin V, Wojcechowskyj JA, Woo JM, Rathore U, Cavero DA, Shifrut E, ... ... Marson A, et al. A functional map of HIV-host interactions in primary human T cells. Nature Communications. 13: 1752. PMID 35365639 DOI: 10.1038/s41467-022-29346-w |
0.792 |
|
| 2022 |
Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, ... ... Marson A, et al. Obesity alters pathology and treatment response in inflammatory disease. Nature. PMID 35355021 DOI: 10.1038/s41586-022-04536-0 |
0.795 |
|
| 2022 |
Byrnes JR, Weeks AM, Shifrut E, Carnevale J, Kirkemo L, Ashworth A, Marson A, Wells JA. Hypoxia is a dominant remodeler of the effector T cell surface proteome relative to activation and regulatory T cell suppression. Molecular & Cellular Proteomics : McP. 100217. PMID 35217172 DOI: 10.1016/j.mcpro.2022.100217 |
0.426 |
|
| 2022 |
Schmidt R, Steinhart Z, Layeghi M, Freimer JW, Bueno R, Nguyen VQ, Blaeschke F, Ye CJ, Marson A. CRISPR activation and interference screens decode stimulation responses in primary human T cells. Science (New York, N.Y.). 375: eabj4008. PMID 35113687 DOI: 10.1126/science.abj4008 |
0.416 |
|
| 2022 |
Sin JH, Kashyap S, Acenas D, Cortez JT, Lee J, Marson A, Matloubian M, Waterfield MR. ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8 T Cell Effector and Memory Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 35110421 DOI: 10.4049/jimmunol.2100996 |
0.385 |
|
| 2021 |
DeSilva D, Ferguson L, Chin GH, Smith BE, Apathy RA, Roth TL, Blaeschke F, Kudla M, Marson A, Ingolia NT, Cate JH. Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. Elife. 10. PMID 34970966 DOI: 10.7554/eLife.74272 |
0.766 |
|
| 2021 |
Gallman AE, Wolfreys FD, Nguyen DN, Sandy M, Xu Y, An J, Li Z, Marson A, Lu E, Cyster JG. Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of -geranylgeranyl-l-glutathione. Science Immunology. 6. PMID 34088745 DOI: 10.1126/sciimmunol.abg1101 |
0.344 |
|
| 2021 |
Hamilton JR, Tsuchida CA, Nguyen DN, Shy BR, McGarrigle ER, Sandoval Espinoza CR, Carr D, Blaeschke F, Marson A, Doudna JA. Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering. Cell Reports. 35: 109207. PMID 34077734 DOI: 10.1016/j.celrep.2021.109207 |
0.423 |
|
| 2021 |
Hiatt J, Cavero DA, McGregor MJ, Zheng W, Budzik JM, Roth TL, Haas KM, Wu D, Rathore U, Meyer-Franke A, Bouzidi MS, Shifrut E, Lee Y, Kumar VE, Dang EV, ... ... Marson A, et al. Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. Cell Reports. 35: 109105. PMID 33979618 DOI: 10.1016/j.celrep.2021.109105 |
0.819 |
|
| 2021 |
Lee Y, Bogdanoff D, Wang Y, Hartoularos GC, Woo JM, Mowery CT, Nisonoff HM, Lee DS, Sun Y, Lee J, Mehdizadeh S, Cantlon J, Shifrut E, Ngyuen DN, Roth TL, ... ... Marson A, et al. XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances. 7. PMID 33883145 DOI: 10.1126/sciadv.abg4755 |
0.703 |
|
| 2021 |
Muller YD, Nguyen DP, Ferreira LMR, Ho P, Raffin C, Valencia RVB, Congrave-Wilson Z, Roth TL, Eyquem J, Van Gool F, Marson A, Perez L, Wells JA, Bluestone JA, Tang Q. The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28. Frontiers in Immunology. 12: 639818. PMID 33833759 DOI: 10.3389/fimmu.2021.639818 |
0.706 |
|
| 2021 |
Siddiqui S, Johansson K, Joo A, Bonser LR, Koh KD, Le Tonqueze O, Bolourchi S, Bautista RA, Zlock L, Roth TL, Marson A, Bhakta NR, Ansel KM, Finkbeiner WE, Erle DJ, et al. Epithelial miR-141 regulates IL-13-induced airway mucus production. Jci Insight. 6. PMID 33682796 DOI: 10.1172/jci.insight.139019 |
0.682 |
|
| 2021 |
Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, ... ... Marson A, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022 |
0.489 |
|
| 2021 |
Roth TL, Marson A. Genetic Disease and Therapy. Annual Review of Pathology. 16: 145-166. PMID 33497260 DOI: 10.1146/annurev-pathmechdis-012419-032626 |
0.658 |
|
| 2020 |
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin CP, Matus-Nicodemos R, Hoh R, Krone MR, Hecht FM, ... ... Marson A, et al. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. Jci Insight. PMID 33351785 DOI: 10.1172/jci.insight.136648 |
0.816 |
|
| 2020 |
Baars MJD, Douma T, Simeonov DR, Myers DR, Kulhanek K, Banerjee S, Zwakenberg S, Baltissen MP, Amini M, de Roock S, van Wijk F, Vermeulen M, Marson A, Roose JP, Vercoulen Y. Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity. European Journal of Immunology. PMID 33065764 DOI: 10.1002/eji.201948451 |
0.343 |
|
| 2020 |
Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, ... ... Marson A, et al. Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. Nature Immunology. PMID 32989329 DOI: 10.1038/s41590-020-0784-4 |
0.797 |
|
| 2020 |
Tan C, Hiwa R, Mueller JL, Vykunta V, Hibiya K, Noviski M, Huizar J, Brooks JF, Garcia J, Heyn C, Li Z, Marson A, Zikherman J. NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting. Nature Immunology. PMID 32868928 DOI: 10.1038/S41590-020-0765-7 |
0.461 |
|
| 2020 |
Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, ... ... Marson A, et al. Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nature Biotechnology. PMID 32855547 DOI: 10.1038/S41587-020-0659-0 |
0.746 |
|
| 2020 |
Dong R, Libby KA, Blaeschke F, Fuchs W, Marson A, Vale RD, Su X. Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR). The Embo Journal. e104730. PMID 32643825 DOI: 10.15252/Embj.2020104730 |
0.492 |
|
| 2020 |
Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, ... Marson A, et al. Layilin augments integrin activation to promote antitumor immunity. The Journal of Experimental Medicine. 217. PMID 32539073 DOI: 10.1084/Jem.20192080 |
0.51 |
|
| 2020 |
Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, ... ... Marson A, et al. Test performance evaluation of SARS-CoV-2 serological assays. Medrxiv : the Preprint Server For Health Sciences. PMID 32511497 DOI: 10.1101/2020.04.25.20074856 |
0.75 |
|
| 2020 |
Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, ... ... Marson A, et al. CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature. PMID 32499641 DOI: 10.1038/S41586-020-2246-4 |
0.799 |
|
| 2020 |
Roth TL, Li PJ, Blaeschke F, Nies JF, Apathy R, Mowery C, Yu R, Nguyen MLT, Lee Y, Truong A, Hiatt J, Wu D, Nguyen DN, Goodman D, Bluestone JA, ... ... Marson A, et al. Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies. Cell. PMID 32302591 DOI: 10.1016/J.Cell.2020.03.039 |
0.817 |
|
| 2020 |
Selyutina A, Persaud M, Simons LM, Bulnes-Ramos A, Buffone C, Martinez-Lopez A, Scoca V, Di Nunzio F, Hiatt J, Marson A, Krogan NJ, Hultquist JF, Diaz-Griffero F. Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core. Cell Reports. 30: 3766-3777.e6. PMID 32187548 DOI: 10.1016/J.Celrep.2020.02.100 |
0.702 |
|
| 2020 |
Gordon DE, Watson A, Roguev A, Zheng S, Jang GM, Kane J, Xu J, Guo JZ, Stevenson E, Swaney DL, Franks-Skiba K, Verschueren E, Shales M, Crosby DC, Frankel AD, ... Marson A, et al. A Quantitative Genetic Interaction Map of HIV Infection. Molecular Cell. PMID 32084337 DOI: 10.1016/J.Molcel.2020.02.004 |
0.339 |
|
| 2020 |
Carnevale J, Shifrut E, Tobin V, Roth T, Woo J, Bui C, Li J, Diolaiti M, Ashworth A, Marson A. Abstract PR08: Discovery of immune regulators in primary human T cells using genome-wide CRISPR screens Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Pr08 |
0.784 |
|
| 2020 |
Le Coz C, Nolan B, Pillarisetti P, Khanna C, Nguyen D, Boggon T, Nicholas S, Verbsky J, Hajjar J, Poon G, Chinn I, Marson A, Romberg N. PU.1 haploinsufficiency arrests pro-B cell development Journal of Allergy and Clinical Immunology. 145: AB344. DOI: 10.1016/J.Jaci.2019.12.085 |
0.334 |
|
| 2019 |
Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, et al. Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. Jci Insight. 4. PMID 31852848 DOI: 10.1172/Jci.Insight.129756 |
0.344 |
|
| 2019 |
Nguyen DN, Roth TL, Li PJ, Chen PA, Apathy R, Mamedov MR, Vo LT, Tobin VR, Goodman D, Shifrut E, Bluestone JA, Puck JM, Szoka FC, Marson A. Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nature Biotechnology. PMID 31819258 DOI: 10.1038/S41587-019-0325-6 |
0.83 |
|
| 2019 |
Ng MSF, Roth TL, Mendoza VF, Marson A, Burt TD. Helios enhances the preferential differentiation of human fetal CD4 naïve T cells into regulatory T cells. Science Immunology. 4. PMID 31757834 DOI: 10.1126/Sciimmunol.Aav5947 |
0.776 |
|
| 2019 |
Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, ... ... Marson A, et al. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nature Genetics. PMID 31570894 DOI: 10.1038/S41588-019-0505-9 |
0.449 |
|
| 2019 |
Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, ... ... Marson A, et al. miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. Cell Reports. 28: 2169-2181.e4. PMID 31433990 DOI: 10.1016/J.Celrep.2019.07.064 |
0.458 |
|
| 2019 |
Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, et al. Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells. Nature Biotechnology. PMID 31359007 DOI: 10.1038/S41587-019-0203-2 |
0.801 |
|
| 2019 |
Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, et al. ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. Cell Host & Microbe. PMID 31253590 DOI: 10.1016/J.Chom.2019.05.008 |
0.674 |
|
| 2019 |
Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, Ware CF, Kronenberg M, Dustin ML, Cyster JG. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. PMID 31204070 DOI: 10.1016/J.Immuni.2019.05.022 |
0.465 |
|
| 2019 |
Schober K, Müller TR, Gökmen F, Grassmann S, Effenberger M, Poltorak M, Stemberger C, Schumann K, Roth TL, Marson A, Busch DH. Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature Biomedical Engineering. PMID 31182835 DOI: 10.1038/S41551-019-0409-0 |
0.762 |
|
| 2019 |
Simeonov DR, Brandt AJ, Chan AY, Cortez JT, Li Z, Woo JM, Lee Y, Carvalho CMB, Indart AC, Roth TL, Zou J, May AP, Lupski JR, Anderson MS, Buaas FW, ... ... Marson A, et al. A large CRISPR-induced bystander mutation causes immune dysregulation. Communications Biology. 2: 70. PMID 30793048 DOI: 10.1038/s42003-019-0321-x |
0.673 |
|
| 2019 |
Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/J.Immuni.2018.12.016 |
0.621 |
|
| 2019 |
Simeonov DR, Marson A. CRISPR-Based Tools in Immunity. Annual Review of Immunology. PMID 30698999 DOI: 10.1146/Annurev-Immunol-042718-041522 |
0.366 |
|
| 2019 |
Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, ... ... Marson A, et al. Thymic regulatory T cells arise via two distinct developmental programs. Nature Immunology. PMID 30643267 DOI: 10.1038/S41590-018-0289-6 |
0.658 |
|
| 2019 |
Hultquist JF, Hiatt J, Schumann K, McGregor MJ, Roth TL, Haas P, Doudna JA, Marson A, Krogan NJ. CRISPR-Cas9 genome engineering of primary CD4 T cells for the interrogation of HIV-host factor interactions. Nature Protocols. 14: 1-27. PMID 30559373 DOI: 10.1038/S41596-018-0069-7 |
0.822 |
|
| 2018 |
Shifrut E, Carnevale J, Tobin V, Roth TL, Woo JM, Bui CT, Li PJ, Diolaiti ME, Ashworth A, Marson A. Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. Cell. PMID 30449619 DOI: 10.1016/J.Cell.2018.10.024 |
0.789 |
|
| 2018 |
Mocciaro A, Roth TL, Bennett HM, Soumillon M, Shah A, Hiatt J, Chapman K, Marson A, Lavieu G. Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device. Communications Biology. 1: 41. PMID 30271925 DOI: 10.1038/s42003-018-0034-6 |
0.818 |
|
| 2018 |
Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, ... Marson A, et al. CRL4 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling. The Embo Journal. PMID 30166453 DOI: 10.15252/Embj.201797508 |
0.666 |
|
| 2018 |
Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, ... ... Marson A, et al. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. PMID 29995861 DOI: 10.1038/S41586-018-0326-5 |
0.838 |
|
| 2018 |
Abbas AK, Trotta E, R Simeonov D, Marson A, Bluestone JA. Revisiting IL-2: Biology and therapeutic prospects. Science Immunology. 3. PMID 29980618 DOI: 10.1126/Sciimmunol.Aat1482 |
0.604 |
|
| 2018 |
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Marson A, et al. Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 29899441 DOI: 10.1038/S41586-018-0227-7 |
0.745 |
|
| 2018 |
Farboud B, Jarvis E, Roth TL, Shin J, Corn JE, Marson A, Meyer BJ, Patel NH, Hochstrasser ML. Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms. Journal of Visualized Experiments : Jove. PMID 29889198 DOI: 10.3791/57350 |
0.746 |
|
| 2018 |
Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC. Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins. Journal of Immunological Methods. PMID 29614266 DOI: 10.1016/J.Jim.2018.03.009 |
0.734 |
|
| 2017 |
Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, et al. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nature Biotechnology. PMID 29227470 DOI: 10.1038/Nbt.4042 |
0.386 |
|
| 2017 |
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Marson A, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963 |
0.491 |
|
| 2017 |
Nguyen MLT, Simeonov DR, Marson A. "T-bet"-ing on autoimmunity variants. Plos Genetics. 13: e1006924. PMID 28880873 DOI: 10.1371/Journal.Pgen.1006924 |
0.397 |
|
| 2017 |
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Marson A, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875 |
0.783 |
|
| 2017 |
Rupp LJ, Schumann K, Roybal KT, Gate RE, Ye CJ, Lim WA, Marson A. CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells. Scientific Reports. 7: 737. PMID 28389661 DOI: 10.1038/S41598-017-00462-8 |
0.445 |
|
| 2016 |
Park RJ, Wang T, Koundakjian D, Hultquist JF, Lamothe-Molina P, Monel B, Schumann K, Yu H, Krupzcak KM, Garcia-Beltran W, Piechocka-Trocha A, Krogan NJ, Marson A, Sabatini DM, Lander ES, et al. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nature Genetics. PMID 27992415 DOI: 10.1038/Ng.3741 |
0.428 |
|
| 2016 |
Hultquist JF, Schumann K, Woo JM, Manganaro L, McGregor MJ, Doudna J, Simon V, Krogan NJ, Marson A. A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells. Cell Reports. 17: 1438-1452. PMID 27783955 DOI: 10.1016/J.Celrep.2016.09.080 |
0.459 |
|
| 2016 |
Van Dyken SJ, Nussbaum JC, Lee J, Molofsky AB, Liang HE, Pollack JL, Gate RE, Haliburton GE, Ye CJ, Marson A, Erle DJ, Locksley RM. A tissue checkpoint regulates type 2 immunity. Nature Immunology. PMID 27749840 DOI: 10.1038/Ni.3582 |
0.399 |
|
| 2016 |
Marson A. Noncoding RNA plugs into a proinflammatory circuit Science Translational Medicine. 8: 321ec7-321ec7. DOI: 10.1126/Scitranslmed.Aaf0855 |
0.483 |
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| 2015 |
Schumann K, Lin S, Boyer E, Simeonov DR, Subramaniam M, Gate RE, Haliburton GE, Ye CJ, Bluestone JA, Doudna JA, Marson A. Generation of knock-in primary human T cells using Cas9 ribonucleoproteins. Proceedings of the National Academy of Sciences of the United States of America. 112: 10437-42. PMID 26216948 DOI: 10.1073/Pnas.1512503112 |
0.683 |
|
| 2015 |
Marson A, Housley WJ, Hafler DA. Genetic basis of autoimmunity. The Journal of Clinical Investigation. 125: 2234-41. PMID 26030227 DOI: 10.1172/Jci78086 |
0.393 |
|
| 2015 |
DuPage M, Chopra G, Quiros J, Rosenthal WL, Morar MM, Holohan D, Zhang R, Turka L, Marson A, Bluestone JA. The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation. Immunity. 42: 227-38. PMID 25680271 DOI: 10.1016/J.Immuni.2015.01.007 |
0.637 |
|
| 2015 |
Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature. 518: 337-43. PMID 25363779 DOI: 10.1038/Nature13835 |
0.478 |
|
| 2015 |
Marson A. Drugging immune regulation Science Translational Medicine. 7: 291ec97-291ec97. DOI: 10.1126/Scitranslmed.Aac5097 |
0.531 |
|
| 2015 |
Marson A. Checkpoint inhibitors continue to check out Science Translational Medicine. 7: 285ec69-285ec69. DOI: 10.1126/Scitranslmed.Aab3135 |
0.305 |
|
| 2014 |
Kofler DM, Marson A, Dominguez-Villar M, Xiao S, Kuchroo VK, Hafler DA. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. The Journal of Clinical Investigation. 124: 2513-22. PMID 24812667 DOI: 10.1172/Jci72973 |
0.461 |
|
| 2014 |
Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, ... ... Marson A, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 40: 477-89. PMID 24745332 DOI: 10.1016/J.Immuni.2014.04.004 |
0.61 |
|
| 2010 |
Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, et al. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 463: 374-8. PMID 20090754 DOI: 10.1038/Nature08684 |
0.709 |
|
| 2008 |
Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/J.Cell.2008.07.020 |
0.736 |
|
| 2008 |
Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell. 3: 132-5. PMID 18682236 DOI: 10.1016/J.Stem.2008.06.019 |
0.545 |
|
| 2007 |
Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, MacIsaac KD, Levine SS, Fraenkel E, von Boehmer H, Young RA. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature. 445: 931-5. PMID 17237765 DOI: 10.1038/Nature05478 |
0.777 |
|
| 2004 |
Daniels MJ, Marson A, Venkitaraman AR. PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein. Nature Structural & Molecular Biology. 11: 1114-21. PMID 15467728 DOI: 10.1038/Nsmb837 |
0.304 |
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