Paul F. Alewood - Publications

Affiliations: 
IMB University of Queensland, Saint Lucia, Queensland, Australia 

237 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations. Toxins. 13. PMID 33672955 DOI: 10.3390/toxins13020146  0.8
2021 Muttenthaler M, King GF, Adams DJ, Alewood PF. Trends in peptide drug discovery. Nature Reviews. Drug Discovery. PMID 33536635 DOI: 10.1038/s41573-020-00135-8  0.8
2021 Armstrong DA, Jin AH, Braga Emidio N, Lewis RJ, Alewood PF, Rosengren KJ. Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from . Marine Drugs. 19. PMID 33530397 DOI: 10.3390/md19020060  0.8
2020 Herzig V, Sunagar K, Wilson DTR, Pineda SS, Israel MR, Dutertre S, McFarland BS, Undheim EAB, Hodgson WC, Alewood PF, Lewis RJ, Bosmans F, Vetter I, King GF, Fry BG. Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958636 DOI: 10.1073/pnas.2004516117  0.8
2020 Liu H, Gruber CW, Alewood PF, Möller A, Muttenthaler M. The oxytocin receptor signalling system and breast cancer: a critical review. Oncogene. PMID 32782397 DOI: 10.1038/s41388-020-01415-8  0.64
2020 Dutt M, Giacomotto J, Ragnarsson L, Andersson A, Brust A, Deakan Z, Alewood PF, Lewis RJ. Re-evaluating the nirvana cabal deployed by piscivorous cone snails. Toxicon : Official Journal of the International Society On Toxinology. 177: S9-S10. PMID 32635128 DOI: 10.1016/j.toxicon.2019.10.044  0.8
2020 Fernandez-Rojo MA, Brust A, Potriquet J, Daley J, Ragnarsson L, Andersson A, Mukhopadhyay P, Wilhelm P, Chin Y, Smallwood T, Clark R, King G, Ramm G, Waddell N, Lewis R, ... ... Alewood P, et al. The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation. Toxicon : Official Journal of the International Society On Toxinology. 177: S2. PMID 32634945 DOI: 10.1016/j.toxicon.2019.10.014  0.8
2020 Nixon SA, Dekan Z, Robinson SD, Guo S, Vetter I, Kotze AC, Alewood PF, King GF, Herzig V. It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant . Biomedicines. 8. PMID 32629771 DOI: 10.3390/biomedicines8070185  0.8
2020 Mueller A, Dekan Z, Kaas Q, Agwa AJ, Starobova H, Alewood PF, Schroeder CI, Mobli M, Deuis JR, Vetter I. Mapping the Molecular Surface of the Analgesic Na1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions. Acs Pharmacology & Translational Science. 3: 535-546. PMID 32566918 DOI: 10.1021/acsptsci.0c00002  0.8
2020 Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF. Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target Na1.7. Biochemical Pharmacology. 114080. PMID 32511987 DOI: 10.1016/j.bcp.2020.114080  0.8
2020 Yin K, Deuis JR, Dekan Z, Jin AH, Alewood PF, King GF, Herzig V, Vetter I. Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of Na1.7. Biomedicines. 8. PMID 32092883 DOI: 10.3390/biomedicines8020037  0.8
2019 Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic acetylcholine receptors. British Journal of Pharmacology. PMID 31877243 DOI: 10.1111/bph.14954  0.8
2019 Dutt M, Giacomotto J, Ragnarsson L, Andersson Å, Brust A, Dekan Z, Alewood PF, Lewis RJ. The α-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa. Scientific Reports. 9: 17841. PMID 31780714 DOI: 10.1038/s41598-019-54186-y  0.8
2019 Jin AH, Muttenthaler M, Dutertre S, Himaya SWA, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Conotoxins: Chemistry and Biology. Chemical Reviews. PMID 31633928 DOI: 10.1021/acs.chemrev.9b00207  0.8
2019 Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, ... ... Alewood PF, et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611414 DOI: 10.1073/pnas.1908662116  0.76
2019 Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. 160: 1766-1780. PMID 31335646 DOI: 10.1097/j.pain.0000000000001567  0.8
2019 Jin AH, Cristofori-Armstrong B, Rash LD, Román González SA, Espinosa RA, Lewis RJ, Alewood PF, Vetter I. Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels. Biochemical Pharmacology. PMID 31028742 DOI: 10.1016/j.bcp.2019.04.025  0.8
2019 Ziegman R, Undheim EAB, Baillie G, Jones A, Alewood PF. Investigation of the estuarine stonefish (Synanceia horrida) venom composition. Journal of Proteomics. PMID 30953730 DOI: 10.1016/j.jprot.2019.04.002  0.72
2019 Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. PMID 30908355 DOI: 10.1097/j.pain.0000000000001567  0.8
2019 Jin AH, Dutertre S, Dutt M, Lavergne V, Jones A, Lewis RJ, Alewood PF. Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, . Marine Drugs. 17. PMID 30893765 DOI: 10.3390/md17030177  0.8
2019 Ziegman R, Brust A, Jha P, Cardoso FC, Lewis RJ, Alewood PF. 'Messy' Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency. Marine Drugs. 17. PMID 30875751 DOI: 10.3390/md17030165  0.8
2019 Dutt M, Dutertre S, Jin AH, Lavergne V, Alewood PF, Lewis RJ. Venomics Reveals Venom Complexity of the Piscivorous Cone Snail, . Marine Drugs. 17. PMID 30669642 DOI: 10.3390/md17010071  0.8
2019 Kakumanu R, Hodgson WC, Ravi R, Alagon A, Harris RJ, Brust A, Alewood PF, Kemp-Harper BK, Fry BG. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat () Blood Feeding. Toxins. 11. PMID 30626071 DOI: 10.3390/toxins11010026  0.8
2018 Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports. 8: 13397. PMID 30194442 DOI: 10.1038/s41598-018-31245-4  0.8
2018 Herzig V, de Araujo AD, Greenwood KP, Chin YK, Windley MJ, Chong Y, Muttenthaler M, Mobli M, Audsley N, Nicholson GM, Alewood PF, King GF. Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines. 6. PMID 30154370 DOI: 10.3390/biomedicines6030090  0.76
2018 Ma L, Chin YKY, Dekan Z, Herzig V, Yuen Chow C, Heighway J, Wing Lam S, Guillemin GJ, Alewood PF, King GF. Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochemical Pharmacology. PMID 30149017 DOI: 10.1016/j.bcp.2018.08.038  0.56
2018 Madio B, Peigneur S, Chin YKY, Hamilton BR, Henriques ST, Smith JJ, Cristofori-Armstrong B, Dekan Z, Boughton BA, Alewood PF, Tytgat J, King GF, Undheim EAB. PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences : Cmls. PMID 30109357 DOI: 10.1007/s00018-018-2897-6  0.6
2018 Ikonomopoulou MP, Fernandez-Rojo MA, Pineda SS, Cabezas-Sainz P, Winnen B, Morales RAV, Brust A, Sánchez L, Alewood PF, Ramm GA, Miles JJ, King GF. Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports. 8: 11519. PMID 30068931 DOI: 10.1038/s41598-018-29826-4  0.8
2018 Brust A, Wang CA, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Corrigendum: Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter. Angewandte Chemie (International Ed. in English). 57: 5203. PMID 29701320 DOI: 10.1002/anie.201803138  0.8
2018 Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP. Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery. 4: 19. PMID 29531816 DOI: 10.1038/s41420-018-0030-0  0.8
2017 Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, ... ... Alewood PF, et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 10. PMID 29208680 DOI: 10.1126/scisignal.aan3398  0.8
2017 Jin AH, Dekan Z, Smout MJ, Wilson D, Dutertre S, Vetter I, Lewis RJ, Loukas A, Daly NL, Alewood PF. Conotoxin Φ-MiXXVIIA from the new superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie (International Ed. in English). PMID 28984021 DOI: 10.1002/anie.201708927  0.8
2017 Sousa SR, Wingerd JS, Brust A, Bladen C, Ragnarsson L, Herzig V, Deuis JR, Dutertre S, Vetter I, Zamponi GW, King GF, Alewood PF, Lewis RJ. Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. Plos One. 12: e0182848. PMID 28880874 DOI: 10.1371/journal.pone.0182848  0.8
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 46816. PMID 28548111 DOI: 10.1038/srep46816  0.8
2017 Cardoso FC, Dekan Z, Smith JJ, Deuis JR, Vetter I, Herzig V, Alewood PF, King GF, Lewis RJ. Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology. PMID 28542706 DOI: 10.1111/bph.13865  0.8
2017 Dekan Z, Heady SJ, Scanlon M, Baldo BA, Lee TH, Aguilar MI, Deuis JR, Vetter I, Elliott AG, Amado M, Cooper MA, Alewood D, Alewood PF. Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the Jack Jumper ant with antimicrobial, membrane disrupting and nociceptive activities. Angewandte Chemie (International Ed. in English). PMID 28513074 DOI: 10.1002/anie.201703360  0.8
2017 Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/s41598-017-01129-0  0.8
2017 Abraham N, Healy M, Ragnarsson L, Brust A, Alewood PF, Lewis RJ. Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor. Scientific Reports. 7: 45466. PMID 28361878 DOI: 10.1038/srep45466  0.8
2017 Di Giglio MG, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T, Rattei T, Arrowsmith S, Wray S, Marek A, Elbert T, Alewood PF, Gloriam DE, Gruber CW. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. 7: 41002. PMID 28145450 DOI: 10.1038/srep41002  0.64
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/srep40883  0.8
2016 Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon : Official Journal of the International Society On Toxinology. PMID 27793656 DOI: 10.1016/j.toxicon.2016.10.013  0.72
2016 Yang DC, Deuis JR, Dashevsky D, Dobson J, Jackson TN, Brust A, Xie B, Koludarov I, Debono J, Hendrikx I, Hodgson WC, Josh P, Nouwens A, Baillie GJ, Bruxner TJ, ... Alewood PF, et al. The Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus). Toxins. 8. PMID 27763551 DOI: 10.3390/toxins8100303  0.8
2016 Touchard A, Brust A, Cardoso FC, Chin YK, Herzig V, Jin AH, Dejean A, Alewood PF, King GF, Orivel J, Escoubas P. Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica Et Biophysica Acta. PMID 27474999 DOI: 10.1016/j.bbagen.2016.07.027  0.8
2016 Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/nature17976  0.56
2016 Deuis JR, Dekan Z, Inserra MC, Lee TH, Aguilar MI, Craik DJ, Lewis RJ, Alewood PF, Mobli M, Schroeder CI, Henriques ST, Vetter I. Development of a μO-conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Target NaV1.8. The Journal of Biological Chemistry. PMID 27026701 DOI: 10.1074/jbc.M116.721662  0.8
2016 Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I. Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain. Toxins. 8. PMID 26999206 DOI: 10.3390/toxins8030078  0.8
2016 Wan J, Alewood PF. Peptide-Decorated Dendrimers and Their Bioapplications. Angewandte Chemie (International Ed. in English). PMID 26990715 DOI: 10.1002/anie.201508428  0.8
2016 Wan J, Brust A, Bhola RF, Jha P, Mobli M, Lewis RJ, Christie MJ, Alewood PF. Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 26910400 DOI: 10.1002/psc.2857  0.8
2016 Brust A, Croker DE, Colless B, Ragnarsson L, Andersson A, Jain K, Caraballo SG, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-derived κ-opioid agonists (conorphins): potent, selective and metabolic stable dynorphinA mimetics with anti-nociceptive properties. Journal of Medicinal Chemistry. PMID 26859603 DOI: 10.1021/acs.jmedchem.5b00911  0.8
2015 Reeks T, Lavergne V, Sunagar K, Jones A, Undheim E, Dunstan N, Fry B, Alewood PF. Deep venomics of the Pseudonaja genus reveals inter- and intra-specific variation. Journal of Proteomics. PMID 26632978 DOI: 10.1016/j.jprot.2015.11.019  0.8
2015 Jin AH, Vetter I, Himaya SW, Alewood PF, Lewis RJ, Dutertre S. Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom. Proteomics. PMID 26506909 DOI: 10.1002/pmic.201500220  0.8
2015 Himaya SW, Jin AH, Dutertre S, Giacomotto J, Mohialdeen H, Vetter I, Alewood PF, Lewis RJ. Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research. 14: 4372-81. PMID 26322961 DOI: 10.1021/acs.jproteome.5b00630  0.8
2015 Deuis JR, Whately E, Brust A, Inserra MC, Asvadi NH, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. Acs Chemical Neuroscience. 6: 1751-8. PMID 26225903 DOI: 10.1021/acschemneuro.5b00113  0.8
2015 Jin AH, Israel MR, Inserra MC, Smith JJ, Lewis RJ, Alewood PF, Vetter I, Dutertre S. δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings. Biological Sciences / the Royal Society. 282. PMID 26156767 DOI: 10.1098/rspb.2015.0817  0.8
2015 Lavergne V, Harliwong I, Jones A, Miller D, Taft RJ, Alewood PF. Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks. Proceedings of the National Academy of Sciences of the United States of America. 112: E3782-91. PMID 26150494 DOI: 10.1073/pnas.1501334112  0.72
2015 Jouiaei M, Yanagihara AA, Madio B, Nevalainen TJ, Alewood PF, Fry BG. Ancient Venom Systems: A Review on Cnidaria Toxins. Toxins. 7: 2251-71. PMID 26094698 DOI: 10.3390/toxins7062251  0.8
2015 Cardoso FC, Dekan Z, Rosengren KJ, Erickson A, Vetter I, Deuis JR, Herzig V, Alewood PF, King GF, Lewis RJ. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Molecular Pharmacology. 88: 291-303. PMID 25979003 DOI: 10.1124/mol.115.098178  0.8
2015 Jouiaei M, Casewell NR, Yanagihara AA, Nouwens A, Cribb BW, Whitehead D, Jackson TN, Ali SA, Wagstaff SC, Koludarov I, Alewood P, Hansen J, Fry BG. Firing the sting: chemically induced discharge of cnidae reveals novel proteins and peptides from box jellyfish (Chironex fleckeri) venom. Toxins. 7: 936-50. PMID 25793725 DOI: 10.3390/toxins7030936  0.8
2015 Jouiaei M, Sunagar K, Federman Gross A, Scheib H, Alewood PF, Moran Y, Fry BG. Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemone. Molecular Biology and Evolution. 32: 1598-610. PMID 25757852 DOI: 10.1093/molbev/msv050  0.8
2015 Reeks T, Jones A, Brust A, Sridharan S, Corcilius L, Wilkinson BL, Thaysen-Andersen M, Payne RJ, Kini RM, Daly NL, Alewood PF. A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie (International Ed. in English). 54: 4828-31. PMID 25735823 DOI: 10.1002/anie.201411914  0.8
2015 Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/jacs.5b00244  0.8
2015 Reeks TA, Fry BG, Alewood PF. Privileged frameworks from snake venom Cellular and Molecular Life Sciences. 72: 1939-1958. PMID 25693678 DOI: 10.1007/s00018-015-1844-z  0.8
2015 Mueller A, Starobova H, Inserra MC, Jin AH, Deuis JR, Dutertre S, Lewis RJ, Alewood PF, Daly NL, Vetter I. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology. 94: 155-63. PMID 25646788 DOI: 10.1016/j.bcp.2015.01.011  0.8
2015 Murali SS, Napier IA, Mohammadi SA, Alewood PF, Lewis RJ, Christie MJ. High-voltage-activated calcium current subtypes in mouse DRG neurons adapt in a subpopulation-specific manner after nerve injury. Journal of Neurophysiology. 113: 1511-9. PMID 25505111 DOI: 10.1152/jn.00608.2014  0.8
2015 Gori A, Wang CI, Harvey PJ, Rosengren KJ, Bhola RF, Gelmi ML, Longhi R, Christie MJ, Lewis RJ, Alewood PF, Brust A. Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic. Angewandte Chemie (International Ed. in English). 54: 1361-4. PMID 25483297 DOI: 10.1002/anie.201409678  0.8
2015 Lavergne V, Harliwong I, Jones A, Miller D, Taft RJ, Alewood PF. Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks Proceedings of the National Academy of Sciences of the United States of America. 112: E3782-E3791. DOI: 10.1073/pnas.1501334112  0.72
2014 Prashanth JR, Brust A, Jin AH, Alewood PF, Dutertre S, Lewis RJ. Cone snail venomics: from novel biology to novel therapeutics. Future Medicinal Chemistry. 6: 1659-75. PMID 25406006 DOI: 10.4155/fmc.14.99  0.8
2014 Jensen JE, Cristofori-Armstrong B, Anangi R, Rosengren KJ, Lau CH, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores. Journal of Medicinal Chemistry. 57: 9195-203. PMID 25337890 DOI: 10.1021/jm501400p  0.8
2014 Dutertre S, Jin AH, Alewood PF, Lewis RJ. Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose. Toxicon : Official Journal of the International Society On Toxinology. 91: 135-44. PMID 25301479 DOI: 10.1016/j.toxicon.2014.09.011  0.8
2014 Vink S, Daly NL, Steen N, Craik DJ, Alewood PF. Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon : Official Journal of the International Society On Toxinology. 90: 308-17. PMID 25172536 DOI: 10.1016/j.toxicon.2014.08.068  0.8
2014 Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42. PMID 25101833 DOI: 10.1016/j.bcp.2014.07.025  0.8
2014 Wang CI, Reeks T, Vetter I, Vergara I, Kovtun O, Lewis RJ, Alewood PF, Durek T. Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry. 53: 3758-66. PMID 24867092 DOI: 10.1021/bi5004475  0.8
2014 Akondi KB, Muttenthaler M, Dutertre S, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Discovery, synthesis, and structure-activity relationships of conotoxins. Chemical Reviews. 114: 5815-47. PMID 24720541 DOI: 10.1021/cr400401e  0.8
2014 Deuis JR, Lim YL, Rodrigues de Sousa S, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology. 16: 1324-32. PMID 24714523 DOI: 10.1093/neuonc/nou048  0.8
2014 Dutertre S, Jin AH, Vetter I, Hamilton B, Sunagar K, Lavergne V, Dutertre V, Fry BG, Antunes A, Venter DJ, Alewood PF, Lewis RJ. Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications. 5: 3521. PMID 24662800 DOI: 10.1038/ncomms4521  0.8
2014 Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology. 171: 3313-27. PMID 24628243 DOI: 10.1111/bph.12686  0.8
2014 Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie (International Ed. in English). 53: 2931-4. PMID 24604812 DOI: 10.1002/anie.201310103  0.8
2014 Brust A, Schroeder CI, Alewood PF. High-throughput synthesis of peptide α-thioesters: a safety catch linker approach enabling parallel hydrogen fluoride cleavage. Chemmedchem. 9: 1038-46. PMID 24591329 DOI: 10.1002/cmdc.201300524  0.8
2014 Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochemical Pharmacology. 89: 276-86. PMID 24561180 DOI: 10.1016/j.bcp.2014.02.008  0.8
2014 Gui J, Liu B, Cao G, Lipchik AM, Perez M, Dekan Z, Mobli M, Daly NL, Alewood PF, Parker LL, King GF, Zhou Y, Jordt SE, Nitabach MN. A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology : Cb. 24: 473-83. PMID 24530065 DOI: 10.1016/j.cub.2014.01.013  0.8
2014 de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications. 5: 3165. PMID 24476666 DOI: 10.1038/ncomms4165  0.8
2014 Jin AH, Vetter I, Dutertre S, Abraham N, Emidio NB, Inserra M, Murali SS, Christie MJ, Alewood PF, Lewis RJ. MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors. Biochemistry. 53: 1-3. PMID 24351107 DOI: 10.1021/bi400882s  0.8
2014 Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie (International Ed. in English). 53: 1017-20. PMID 24323786 DOI: 10.1002/anie.201308898  0.8
2014 Akondi KB, Lewis RJ, Alewood PF. Re-engineering the μ-conotoxin SIIIA scaffold. Biopolymers. 101: 347-54. PMID 23913763 DOI: 10.1002/bip.22368  0.8
2013 Sadeghi M, Murali SS, Lewis RJ, Alewood PF, Mohammadi S, Christie MJ. Novel ω-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration. Molecular Pain. 9: 51. PMID 24139484 DOI: 10.1186/1744-8069-9-51  0.8
2013 Lavergne V, Dutertre S, Jin AH, Lewis RJ, Taft RJ, Alewood PF. Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. Bmc Genomics. 14: 708. PMID 24131469 DOI: 10.1186/1471-2164-14-708  0.8
2013 Brust A, Wang CI, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Ed. in English). 52: 12020-3. PMID 24115503 DOI: 10.1002/anie.201304660  0.8
2013 Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/jbc.M113.512582  0.8
2013 Jin AH, Dutertre S, Kaas Q, Lavergne V, Kubala P, Lewis RJ, Alewood PF. Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Molecular & Cellular Proteomics : McP. 12: 3824-33. PMID 24043424 DOI: 10.1074/mcp.M113.030353  0.8
2013 Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/j.bcp.2013.07.016  0.8
2013 Ruder T, Ali SA, Ormerod K, Brust A, Roymanchadi ML, Ventura S, Undheim EA, Jackson TN, Mercier AJ, King GF, Alewood PF, Fry BG. Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides. 47: 71-6. PMID 23850991 DOI: 10.1016/j.peptides.2013.07.002  0.8
2013 Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. Quantification of lactosylation of whey proteins in stored milk powder using multiple reaction monitoring. Food Chemistry. 141: 1203-10. PMID 23790905 DOI: 10.1016/j.foodchem.2013.03.073  0.8
2013 Smith JJ, Vetter I, Lewis RJ, Peigneur S, Tytgat J, Lam A, Gallant EM, Beard NA, Alewood PF, Dulhunty AF. Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins. Proceedings of the National Academy of Sciences of the United States of America. 110: 8906-11. PMID 23671114 DOI: 10.1073/pnas.1214062110  0.8
2013 de Araujo AD, Herzig V, Windley MJ, Dziemborowicz S, Mobli M, Nicholson GM, Alewood PF, King GF. Do vicinal disulfide bridges mediate functionally important redox transformations in proteins? Antioxidants & Redox Signaling. 19: 1976-80. PMID 23646911 DOI: 10.1089/ars.2013.5365  0.76
2013 Ghassemian A, Vila-Farrés X, Alewood PF, Durek T. Solid phase synthesis of peptide-selenoesters. Bioorganic & Medicinal Chemistry. 21: 3473-8. PMID 23608106 DOI: 10.1016/j.bmc.2013.03.076  0.72
2013 Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. Acs Chemical Biology. 8: 1215-22. PMID 23527544 DOI: 10.1021/cb400012k  0.8
2013 Smith JJ, Herzig V, King GF, Alewood PF. The insecticidal potential of venom peptides. Cellular and Molecular Life Sciences : Cmls. 70: 3665-93. PMID 23525661 DOI: 10.1007/s00018-013-1315-3  0.56
2013 Ghassemian A, Wang CI, Yau MK, Reid RC, Lewis RJ, Fairlie DP, Alewood PF, Durek T. Efficient chemical synthesis of human complement protein C3a. Chemical Communications (Cambridge, England). 49: 2356-8. PMID 23407800 DOI: 10.1039/c3cc40537k  0.8
2013 Brust A, Sunagar K, Undheim EA, Vetter I, Yang DC, Yang DC, Casewell NR, Jackson TN, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, et al. Differential evolution and neofunctionalization of snake venom metalloprotease domains. Molecular & Cellular Proteomics : McP. 12: 651-63. PMID 23242553 DOI: 10.1074/mcp.M112.023135  0.8
2013 Dutertre S, Jin AH, Kaas Q, Jones A, Alewood PF, Lewis RJ. Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Molecular & Cellular Proteomics : McP. 12: 312-29. PMID 23152539 DOI: 10.1074/mcp.M112.021469  0.8
2013 Brust A, Sunagar K, Undheim EAB, Vetter I, Yang DC, Casewell NR, Jackson TNW, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, Fry BG. Differential evolution and neofunctionalization of snake venom metalloprotease domains (Molecular and Cellular Proteomics 2013, 12, (651-663)) Molecular and Cellular Proteomics. 12: 1488. DOI: 10.1074/mcp.A112.023135  0.8
2013 Le TT, Holland JW, Bhandari B, Alewood PF, Deeth HC. Direct evidence for the role of Maillard reaction products in protein cross-linking in milk powder during storage International Dairy Journal. 31: 81-93. DOI: 10.1016/j.idairyj.2013.02.013  0.8
2012 Smith JJ, Jones A, Alewood PF. Mass landscapes of seven scorpion species: The first analyses of Australian species with 1,5-DAN matrix. Journal of Venom Research. 3: 7-14. PMID 23236582  0.72
2012 Schroeder CI, Nielsen KJ, Adams DA, Loughnan M, Thomas L, Alewood PF, Lewis RJ, Craik DJ. Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers. 98: 345-56. PMID 23193599  0.8
2012 de Araujo AD, Mobli M, King GF, Alewood PF. Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie (International Ed. in English). 51: 10298-302. PMID 22991244 DOI: 10.1002/anie.201204229  0.76
2012 Jensen JE, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3. Marine Drugs. 10: 1511-27. PMID 22851922 DOI: 10.3390/md10071511  0.8
2012 Lavergne V, Taft RJ, Alewood PF. Cysteine-rich mini-proteins in human biology. Current Topics in Medicinal Chemistry. 12: 1514-33. PMID 22827521  0.44
2012 Schroeder CI, Adams D, Thomas L, Alewood PF, Lewis RJ. N- and C-terminal extensions of μ-conotoxins increase potency and selectivity for neuronal sodium channels. Biopolymers. 98: 161-5. PMID 22733528 DOI: 10.1002/bip.22032  0.8
2012 Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochemical Pharmacology. 84: 540-8. PMID 22609441 DOI: 10.1016/j.bcp.2012.05.008  0.8
2012 Dekan Z, Wang CI, Andrews RK, Lewis RJ, Alewood PF. Conotoxin engineering: dual pharmacophoric noradrenaline transport inhibitor/integrin binding peptide with improved stability. Organic & Biomolecular Chemistry. 10: 5791-4. PMID 22581211 DOI: 10.1039/c2ob25133g  0.8
2012 Vetter I, Mozar CA, Durek T, Wingerd JS, Alewood PF, Christie MJ, Lewis RJ. Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells. Biochemical Pharmacology. 83: 1562-71. PMID 22410003 DOI: 10.1016/j.bcp.2012.02.022  0.8
2012 Beaumont KA, Smit DJ, Liu YY, Chai E, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Sturm RA. Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. Pigment Cell & Melanoma Research. 25: 370-4. PMID 22364200 DOI: 10.1111/j.1755-148X.2012.00990.x  0.8
2012 Hjørringgaard CU, Brust A, Alewood PF. Evaluation of COMU as a coupling reagent for in situ neutralization Boc solid phase peptide synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 199-207. PMID 22252935 DOI: 10.1002/psc.1438  0.8
2012 Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marí F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/j.bcp.2011.11.006  0.8
2012 Holland JW, Gupta R, Deeth HC, Alewood PF. UHT milk contains multiple forms of α s1-casein that undergo degradative changes during storage Food Chemistry. 133: 689-696. DOI: 10.1016/j.foodchem.2012.01.070  0.8
2012 Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. A proteomic approach to detect lactosylation and other chemical changes in stored milk protein concentrate Food Chemistry. 132: 655-662. DOI: 10.1016/j.foodchem.2011.11.012  0.8
2011 Muttenthaler M, Akondi KB, Alewood PF. Structure-activity studies on alpha-conotoxins. Current Pharmaceutical Design. 17: 4226-41. PMID 22204424  0.64
2011 de Araujo AD, Christensen C, Buchardt J, Kent SB, Alewood PF. Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 13983-6. PMID 22084036 DOI: 10.1002/chem.201102732  0.76
2011 Mobli M, Morgenstern D, King GF, Alewood PF, Muttenthaler M. Site-specific pK(a) determination of selenocysteine residues in selenovasopressin by using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 50: 11952-5. PMID 22002840 DOI: 10.1002/anie.201104169  0.76
2011 Durek T, Alewood PF. Preformed selenoesters enable rapid native chemical ligation at intractable sites. Angewandte Chemie (International Ed. in English). 50: 12042-5. PMID 21997950 DOI: 10.1002/anie.201105512  0.72
2011 Dekan Z, Vetter I, Daly NL, Craik DJ, Lewis RJ, Alewood PF. α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society. 133: 15866-9. PMID 21899353 DOI: 10.1021/ja206408q  0.8
2011 Smith JJ, Hill JM, Little MJ, Nicholson GM, King GF, Alewood PF. Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif. Proceedings of the National Academy of Sciences of the United States of America. 108: 10478-83. PMID 21670253 DOI: 10.1073/pnas.1103501108  0.56
2011 de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/anie.201101642  0.8
2011 Wijffels G, Johnson WM, Oakley AJ, Turner K, Epa VC, Briscoe SJ, Polley M, Liepa AJ, Hofmann A, Buchardt J, Christensen C, Prosselkov P, Dalrymple BP, Alewood PF, Jennings PA, et al. Binding inhibitors of the bacterial sliding clamp by design. Journal of Medicinal Chemistry. 54: 4831-8. PMID 21604761 DOI: 10.1021/jm2004333  0.8
2011 Holland JW, Gupta R, Deeth HC, Alewood PF. Proteomic analysis of temperature-dependent changes in stored UHT milk Journal of Agricultural and Food Chemistry. 59: 1837-1846. PMID 21322568 DOI: 10.1021/jf104395v  0.8
2011 Beaumont KA, Wong SS, Ainger SA, Liu YY, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Leonard JH, Sturm RA. Melanocortin MC1 receptor in human genetics and model systems European Journal of Pharmacology. 660: 103-110. PMID 21199646 DOI: 10.1016/j.ejphar.2010.11.040  0.8
2011 Rash LD, Morales RA, Vink S, Alewood PF. De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina). Toxicon : Official Journal of the International Society On Toxinology. 57: 208-16. PMID 21115026 DOI: 10.1016/j.toxicon.2010.11.012  0.44
2011 Vetter I, Davis JL, Rash LD, Anangi R, Mobli M, Alewood PF, Lewis RJ, King GF. Venomics: A new paradigm for natural products-based drug discovery Amino Acids. 40: 15-28. PMID 20177945 DOI: 10.1007/s00726-010-0516-4  0.8
2011 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis J, Alewood PF, Christie MJ, Adams DJ. Analgesic ω-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels (Molecular Pharmacology (2010) 77, (139-148)) Molecular Pharmacology. 80: 356. DOI: 10.1124/mol.80.2.356  0.8
2010 Muttenthaler M, Andersson A, de Araujo AD, Dekan Z, Lewis RJ, Alewood PF. Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of Medicinal Chemistry. 53: 8585-96. PMID 21117646 DOI: 10.1021/jm100989w  0.8
2010 Alewood D, Hopping G, Brust A, Reid RC, Alewood PF. Benzhydrylamine linker grafting: a strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 551-7. PMID 20862722 DOI: 10.1002/psc.1248  0.8
2010 Morales RA, Daly NL, Vetter I, Mobli M, Napier IA, Craik DJ, Lewis RJ, Christie MJ, King GF, Alewood PF, Durek T. Chemical synthesis and structure of the prokineticin Bv8. Chembiochem : a European Journal of Chemical Biology. 11: 1882-8. PMID 20677202 DOI: 10.1002/cbic.201000330  0.8
2010 Muttenthaler M, Ramos YG, Feytens D, de Araujo AD, Alewood PF. p-Nitrobenzyl protection for cysteine and selenocysteine: a more stable alternative to the acetamidomethyl group. Biopolymers. 94: 423-32. PMID 20593464 DOI: 10.1002/bip.21502  0.76
2010 Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 285: 22254-63. PMID 20466726 DOI: 10.1074/jbc.M110.111880  0.8
2010 Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22. PMID 20163143 DOI: 10.1021/ja910602h  0.8
2010 Luo S, Akondi KB, Zhangsun D, Wu Y, Zhu X, Hu Y, Christensen S, Dowell C, Daly NL, Craik DJ, Wang CIA, Lewis RJ, Alewood PF, McIntosh JM. Atypical α-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor Journal of Biological Chemistry. 285: 12355-12366. PMID 20145249 DOI: 10.1074/jbc.M109.079012  0.8
2010 Armishaw CJ, Dutton JL, Craik DJ, Alewood PF. Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogs. Biopolymers. 94: 307-13. PMID 20013812 DOI: 10.1002/bip.21360  0.8
2010 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ. Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels. Molecular Pharmacology. 77: 139-48. PMID 19892914 DOI: 10.1124/mol.109.058834  0.8
2009 Mobli M, de Araújo AD, Lambert LK, Pierens GK, Windley MJ, Nicholson GM, Alewood PF, King GF. Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 48: 9312-4. PMID 19890933 DOI: 10.1002/anie.200905206  0.76
2009 Brust A, Palant E, Croker DE, Colless B, Drinkwater R, Patterson B, Schroeder CI, Wilson D, Nielsen CK, Smith MT, Alewood D, Alewood PF, Lewis RJ. chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry. 52: 6991-7002. PMID 19860431 DOI: 10.1021/jm9003413  0.8
2009 Vernall AJ, Cassidy P, Alewood PF. A single alpha-helical turn stabilized by replacement of an internal hydrogen bond with a covalent ethylene bridge. Angewandte Chemie (International Ed. in English). 48: 5675-8. PMID 19562809 DOI: 10.1002/anie.200901059  0.8
2009 Ueberheide BM, Fenyö D, Alewood PF, Chait BT. Rapid sensitive analysis of cysteine rich peptide venom components. Proceedings of the National Academy of Sciences of the United States of America. 106: 6910-5. PMID 19380747 DOI: 10.1073/pnas.0900745106  0.8
2009 Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon. 54: 56-61. PMID 19306891 DOI: 10.1016/j.toxicon.2009.03.014  0.8
2009 Pages G, Torres AM, Ju P, Bansal PS, Alewood PF, Kuchel PW, Vandenberg JI. Structure of the pore-helix of the hERG K(+) channel. European Biophysics Journal : Ebj. 39: 111-20. PMID 19305991 DOI: 10.1007/s00249-009-0433-1  0.4
2009 Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/jbc.M804950200  0.8
2009 Hopping G, Lewis RJ, Alewood PF. Rapid access to ω-conotoxin chimeras using native chemical ligation Australian Journal of Chemistry. 62: 1333-1338. DOI: 10.1071/CH09216  0.8
2008 Muttenthaler M, Alewood PF. Selenopeptide chemistry. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 1223-39. PMID 18951416 DOI: 10.1002/psc.1075  0.64
2008 Poth AG, Deeth HC, Alewood PF, Holland JW. Analysis of the human casein phosphoproteome by 2-D electrophoresis and MALDI-TOF/TOF MS reveals new phosphoforms Journal of Proteome Research. 7: 5017-5027. PMID 18847231 DOI: 10.1021/pr800387s  0.8
2008 Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84. PMID 18754612 DOI: 10.1021/jm800278k  0.8
2008 Holland JW, Deeth HC, Alewood PF. Analysis of disulphide linkages in bovine κ-casein oligomers using two-dimensional electrophoresis Electrophoresis. 29: 2402-2410. PMID 18548457 DOI: 10.1002/elps.200700840  0.8
2008 Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. The Journal of Biological Chemistry. 283: 21621-8. PMID 18522941 DOI: 10.1074/jbc.M802852200  0.8
2008 Imperial JS, Chen P, Sporning A, Terlau H, Daly NL, Craik DJ, Alewood PF, Olivera BM. Tyrosine-rich conopeptides affect voltage-gated K+ channels. The Journal of Biological Chemistry. 283: 23026-32. PMID 18505731 DOI: 10.1074/jbc.M800084200  0.8
2008 Dutertre S, Croker D, Daly NL, Andersson A, Muttenthaler M, Lumsden NG, Craik DJ, Alewood PF, Guillon G, Lewis RJ. Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. The Journal of Biological Chemistry. 283: 7100-8. PMID 18174156 DOI: 10.1074/jbc.M706477200  0.48
2007 Latham CF, Hu SH, Gee CL, Armishaw CJ, Alewood PF, James DE, Martin JL. Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 524-8. PMID 17554178 DOI: 10.1107/S1744309107022361  0.8
2007 Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28  0.8
2007 Chandrashekaran IR, Yao S, Wang CC, Bansal PS, Alewood PF, Forbes BE, Wallace JC, Bach LA, Norton RS. The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs. Biochemistry. 46: 3065-74. PMID 17305365 DOI: 10.1021/bi0619876  0.4
2007 Yang Z, Yan WX, Cai H, Tedla N, Armishaw C, Di Girolamo N, Wang HW, Hampartzoumian T, Simpson JL, Gibson PG, Hunt J, Hart P, Hughes JM, Perry MA, Alewood PF, et al. S100A12 provokes mast cell activation: a potential amplification pathway in asthma and innate immunity. The Journal of Allergy and Clinical Immunology. 119: 106-14. PMID 17208591 DOI: 10.1016/j.jaci.2006.08.021  0.8
2007 Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Molecular Pharmacology. 71: 676-85. PMID 17142296 DOI: 10.1124/mol.106.028225  0.8
2007 Nair DG, Fry BG, Alewood P, Kumar PP, Kini RM. Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins. The Biochemical Journal. 402: 93-104. PMID 17044815 DOI: 10.1042/BJ20060318  0.8
2007 Torres AM, Tsampazi M, Kennett EC, Belov K, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. Characterization and isolation of L-to-D-amino-acid-residue isomerase from platypus venom. Amino Acids. 32: 63-8. PMID 16729187 DOI: 10.1007/s00726-006-0346-6  0.4
2007 Schnölzer M, Alewood P, Jones A, Alewood D, Kent SBH. In situ neutralization in boc-chemistry solid phase peptide synthesis: Rapid, high yield assembly of difficult sequences International Journal of Peptide Research and Therapeutics. 13: 31-44. DOI: 10.1007/s10989-006-9059-7  0.72
2006 St Pierre L, Flight S, Masci PP, Hanchard KJ, Lewis RJ, Alewood PF, de Jersey J, Lavin MF. Cloning and characterisation of natriuretic peptides from the venom glands of Australian elapids. Biochimie. 88: 1923-31. PMID 16908092 DOI: 10.1016/j.biochi.2006.06.014  0.8
2006 Latham CF, Lopez JA, Hu SH, Gee CL, Westbury E, Blair DH, Armishaw CJ, Alewood PF, Bryant NJ, James DE, Martin JL. Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking. Traffic (Copenhagen, Denmark). 7: 1408-19. PMID 16899085 DOI: 10.1111/j.1600-0854.2006.00474.x  0.8
2006 Imperial JS, Bansal PS, Alewood PF, Daly NL, Craik DJ, Sporning A, Terlau H, López-Vera E, Bandyopadhyay PK, Olivera BM. A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry. 45: 8331-40. PMID 16819832 DOI: 10.1021/bi060263r  0.8
2006 Dutertre S, Lumsden NG, Alewood PF, Lewis RJ. Isolation and characterisation of conomap-Vt, a D-amino acid containing excitatory peptide from the venom of a vermivorous cone snail. Febs Letters. 580: 3860-6. PMID 16797543 DOI: 10.1016/j.febslet.2006.06.011  0.44
2006 Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/jbc.M603703200  0.8
2006 Holland JW, Deeth HC, Alewood PF. Resolution and characterisation of multiple isoforms of bovine κ-casein by 2-DE following a reversible cysteine-tagging enrichment strategy Proteomics. 6: 3087-3095. PMID 16619295 DOI: 10.1002/pmic.200500780  0.8
2006 Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists Journal of Biological Chemistry. 281: 14136-14143. PMID 16500898 DOI: 10.1074/jbc.M512419200  0.8
2006 Torres AM, Tsampazi M, Tsampazi C, Kennett EC, Belov K, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. Mammalian l-to-d-amino-acid-residue isomerase from platypus venom. Febs Letters. 580: 1587-91. PMID 16480722 DOI: 10.1016/j.febslet.2006.01.089  0.4
2005 Torres AM, Tsampazi C, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties. The Biochemical Journal. 391: 215-20. PMID 16033333 DOI: 10.1042/BJ20050900  0.4
2005 Alewood D, Nielsen K, Alewood PF, Craik DJ, Andrews P, Nerrie M, White S, Domagala T, Walker F, Rothacker J, Burgess AW, Nice EC. The role of disulfide bonds in the structure and function of murine epidermal growth factor (mEGF). Growth Factors (Chur, Switzerland). 23: 97-110. PMID 16019431 DOI: 10.1080/08977190500096061  0.8
2005 Nilsson KP, Lovelace ES, Caesar CE, TynngÃ¥rd N, Alewood PF, Johansson HM, Sharpe IA, Lewis RJ, Daly NL, Craik DJ. Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter. Biopolymers. 80: 815-23. PMID 15931669 DOI: 10.1002/bip.20302  0.8
2005 Holland JW, Deeth HC, Alewood PF. Analysis of O-glycosylation site occupancy in bovine κ-casein glycoforms separated by two-dimensional gel electrophoresis Proteomics. 5: 990-1002. PMID 15693064 DOI: 10.1002/pmic.200401098  0.8
2004 Ravasi T, Hsu K, Goyette J, Schroder K, Yang Z, Rahimi F, Miranda LP, Alewood PF, Hume DA, Geczy C. Probing the S100 protein family through genomic and functional analysis. Genomics. 84: 10-22. PMID 15203200 DOI: 10.1016/j.ygeno.2004.02.002  0.8
2004 Wijffels G, Dalrymple BP, Prosselkov P, Kongsuwan K, Epa VC, Lilley PE, Jergic S, Buchardt J, Brown SE, Alewood PF, Jennings PA, Dixon NE. Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins. Biochemistry. 43: 5661-71. PMID 15134440 DOI: 10.1021/bi036229j  0.8
2004 Holland JW, Deeth HC, Alewood PF. Proteomic analysis of κ-casein micro-heterogeneity Proteomics. 4: 743-752. PMID 14997496 DOI: 10.1002/pmic.200300613  0.8
2004 Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/jm031010o  0.8
2003 Torres AM, Bansal PS, Sunde M, Clarke CE, Bursill JA, Smith DJ, Bauskin A, Breit SN, Campbell TJ, Alewood PF, Kuchel PW, Vandenberg JI. Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation. The Journal of Biological Chemistry. 278: 42136-48. PMID 12902341 DOI: 10.1074/jbc.M212824200  0.8
2003 Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. The Journal of Biological Chemistry. 278: 40317-23. PMID 12885787 DOI: 10.1074/jbc.M213030200  0.8
2003 Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of Biological Chemistry. 278: 34451-7. PMID 12824165 DOI: 10.1074/jbc.M305410200  0.8
2003 Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/jbc.M212628200  0.8
2003 Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. Journal of Medicinal Chemistry. 46: 1266-72. PMID 12646037 DOI: 10.1021/jm020426j  0.8
2003 Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/jbc.M210280200  0.8
2002 Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. The Journal of Biological Chemistry. 277: 48849-57. PMID 12376538 DOI: 10.1074/jbc.M208842200  0.8
2002 Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. The Journal of Biological Chemistry. 277: 27247-55. PMID 12006587 DOI: 10.1074/jbc.M201611200  0.8
2002 Rosengren KJ, Wilson D, Daly NL, Alewood PF, Craik DJ. Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry. 41: 3294-301. PMID 11876637 DOI: 10.1021/bi011932y  0.52
2001 Bourne GT, Golding SW, McGeary RP, Meutermans WD, Jones A, Marshall GR, Alewood PF, Smythe ML. The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides. The Journal of Organic Chemistry. 66: 7706-13. PMID 11701025 DOI: 10.1021/jo010580y  0.8
2001 Fry BG, Wickramaratna JC, Jones A, Alewood PF, Hodgson WC. Species and regional variations in the effectiveness of antivenom against the in vitro neurotoxicity of death adder (Acanthophis) venoms. Toxicology and Applied Pharmacology. 175: 140-8. PMID 11543646 DOI: 10.1006/taap.2001.9233  0.72
2001 Sharpe IA, Gehrmann J, Loughnan ML, Thomas L, Adams DA, Atkins A, Palant E, Craik DJ, Adams DJ, Alewood PF, Lewis RJ. Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nature Neuroscience. 4: 902-7. PMID 11528421 DOI: 10.1038/nn0901-902  0.8
2001 Wang XH, Connor M, Wilson D, Wilson HI, Nicholson GM, Smith R, Shaw D, Mackay JP, Alewood PF, Christie MJ, King GF. Discovery and structure of a potent and highly specific blocker of insect calcium channels. The Journal of Biological Chemistry. 276: 40306-12. PMID 11522785 DOI: 10.1074/jbc.M105206200  0.8
2001 Miranda LP, Tao T, Jones A, Chernushevich I, Standing KG, Geczy CL, Alewood PF. Total chemical synthesis and chemotactic activity of human S100A12 (EN-RAGE). Febs Letters. 488: 85-90. PMID 11163801 DOI: 10.1016/S0014-5793(00)02392-9  0.72
2000 Tyndall JD, Reid RC, Tyssen DP, Jardine DK, Todd B, Passmore M, March DR, Pattenden LK, Bergman DA, Alewood D, Hu SH, Alewood PF, Birch CJ, Martin JL, Fairlie DP. Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. Journal of Medicinal Chemistry. 43: 3495-504. PMID 11000004 DOI: 10.1021/jm000013n  0.8
2000 Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L, Jones A, Matheson JL, Drinkwater R, Andrews PR, Alewood PF. Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. The Journal of Biological Chemistry. 275: 35335-44. PMID 10938268 DOI: 10.1074/jbc.M002252200  0.8
2000 Hill JM, Alewood PF, Craik DJ. Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 2. Three-dimensional solution structure. European Journal of Biochemistry / Febs. 267: 4649-57. PMID 10903497 DOI: 10.1046/j.1432-1327.2000.01507.x  0.8
2000 Hill JM, Atkins AR, Loughnan ML, Jones A, Adams DA, Martin RC, Lewis RJ, Craik DJ, Alewood PF. Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 1. Isolation, characterization and chemical synthesis. European Journal of Biochemistry / Febs. 267: 4642-8. PMID 10903496 DOI: 10.1046/j.1432-1327.2000.01508.x  0.8
1999 Gehrmann J, Daly NL, Alewood PF, Craik DJ. Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance. Journal of Medicinal Chemistry. 42: 2364-72. PMID 10395477 DOI: 10.1021/JM990114P  0.4
1999 Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP. Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry. 38: 7978-88. PMID 10387041 DOI: 10.1021/bi990174x  0.8
1999 Nielsen KJ, Adams D, Thomas L, Bond T, Alewood PF, Craik DJ, Lewis RJ. Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels. Journal of Molecular Biology. 289: 1405-21. PMID 10373375 DOI: 10.1006/jmbi.1999.2817  0.8
1999 Nielsen KJ, Adams DA, Alewood PF, Lewis RJ, Thomas L, Schroeder T, Craik DJ. Effects of chirality at Tyr13 on the structure-activity relationships of omega-conotoxins from Conus magus. Biochemistry. 38: 6741-51. PMID 10346894 DOI: 10.1021/bi982980u  0.8
1999 Harrison CA, Raftery MJ, Walsh J, Alewood P, Iismaa SE, Thliveris S, Geczy CL. Oxidation regulates the inflammatory properties of the murine S100 protein S100A8. The Journal of Biological Chemistry. 274: 8561-9. PMID 10085090 DOI: 10.1074/jbc.274.13.8561  0.8
1999 Nielsen KJ, Skjaerbaek N, Dooley M, Adams DA, Mortensen M, Dodd PR, Craik DJ, Alewood PF, Lewis RJ. Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulators. Journal of Medicinal Chemistry. 42: 415-26. PMID 9986713 DOI: 10.1021/jm981052q  0.8
1998 Hill JM, Oomen CJ, Miranda LP, Bingham JP, Alewood PF, Craik DJ. Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity. Biochemistry. 37: 15621-30. PMID 9843366 DOI: 10.1021/bi981535w  0.8
1998 Wu QX, King MA, Donovan GR, Alewood D, Alewood P, Sawyer WH, Baldo BA. Cytotoxicity of pilosulin 1, a peptide from the venom of the jumper ant Myrmecia pilosula. Biochimica Et Biophysica Acta. 1425: 74-80. PMID 9813247 DOI: 10.1016/S0304-4165(98)00052-X  0.8
1998 Lackmann M, Harpur AG, Oates AC, Mann RJ, Gabriel A, Meutermans W, Alewood PF, Kerr IM, Stark GR, Wilks AF. Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes. Growth Factors (Chur, Switzerland). 16: 39-51. PMID 9777369 DOI: 10.3109/08977199809017490  0.8
1998 Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, Livett BG, Down JG, Jones A, Alewood PF, Lewis RJ. alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 273: 15667-74. PMID 9624161 DOI: 10.1074/jbc.273.25.15667  0.8
1998 Gehrmann J, Alewood PF, Craik DJ. Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability. Journal of Molecular Biology. 278: 401-15. PMID 9571060 DOI: 10.1006/JMBI.1998.1701  0.36
1997 Scanlon MJ, Naranjo D, Thomas L, Alewood PF, Lewis RJ, Craik DJ. Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA. Structure (London, England : 1993). 5: 1585-97. PMID 9438859 DOI: 10.1016/S0969-2126(97)00307-9  0.8
1997 Hu SH, Gehrmann J, Alewood PF, Craik DJ, Martin JL. Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI. Biochemistry. 36: 11323-30. PMID 9298951 DOI: 10.1021/BI9713052  0.32
1997 Hill JM, Alewood PF, Craik DJ. Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry. Structure (London, England : 1993). 5: 571-83. PMID 9115446 DOI: 10.1016/S0969-2126(97)00212-8  0.8
1997 Skjaerbaek N, Nielsen KJ, Lewis RJ, Alewood P, Craik DJ. Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy. The Journal of Biological Chemistry. 272: 2291-9. PMID 8999936 DOI: 10.1074/jbc.272.4.2291  0.8
1996 Nielsen KJ, Thomas L, Lewis RJ, Alewood PF, Craik DJ. A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. Journal of Molecular Biology. 263: 297-310. PMID 8913308 DOI: 10.1006/jmbi.1996.0576  0.8
1996 Donovan GR, Street MD, Tetaz T, Smith AI, Alewood D, Alewood P, Sutherland SK, Baldo BA. Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products. Biochemistry and Molecular Biology International. 39: 877-85. PMID 8866004 DOI: 10.1080/15216549600201022  0.8
1996 Hill JM, Alewood PF, Craik DJ. Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Biochemistry. 35: 8824-35. PMID 8688418 DOI: 10.1021/bi960073o  0.8
1996 Raftery MJ, Harrison CA, Alewood P, Jones A, Geczy CL. Isolation of the murine S100 protein MRP14 (14 kDa migration-inhibitory-factor-related protein) from activated spleen cells: characterization of post-translational modifications and zinc binding. The Biochemical Journal. 316: 285-93. PMID 8645219 DOI: 10.1042/BJ3160285  0.8
1996 Jones A, Bingham JP, Gehrmann J, Bond T, Loughnan M, Atkins A, Lewis RJ, Alewood PF. Isolation and characterization of conopeptides by high-performance liquid chromatography combined with mass spectrometry and tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 10: 138-43. PMID 8563013 DOI: 10.1002/(SICI)1097-0231(19960115)10:1<138::AID-RCM442>3.0.CO;2-3  0.8
1995 Nicholls IA, Craik DJ, Alewood PF. NMR and molecular modelling based conformational analysis of some N-alkyl 1- and 2-benzazepinones: useful central nervous system agent design motifs. Biochemical and Biophysical Research Communications. 205: 98-104. PMID 7999141 DOI: 10.1006/BBRC.1994.2635  0.32
1995 Englebretsen DR, Garnham BG, Bergman DA, Alewood PF. A novel thioether linker: Chemical synthesis of a HIV-1 protease analogue by thioether ligation Tetrahedron Letters. 36: 8871-8874. DOI: 10.1016/0040-4039(95)01843-7  0.8
1995 Bergman DA, Alewood D, Alewood PF, Andrews JL, Brinkworth RI, Englebretsen DR, Kent SBH. Kinetic properties of HIV-1 protease produced by total chemical synthesis with cysteine residues replaced by isosteric L-α-amino-n-butyric acid Letters in Peptide Science. 2: 99-107. DOI: 10.1007/BF00128504  0.8
1994 Lewis RJ, Holmes MJ, Alewood PF, Jones A. Ionspray mass spectrometry of ciguatoxin-1, maitotoxin-2 and -3, and related marine polyether toxins. Natural Toxins. 2: 56-63. PMID 8075894 DOI: 10.1002/NT.2620020203  0.8
1994 Monks SA, Gould AR, Lumley PE, Alewood PF, Kem WR, Goss NH, Norton RS. Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone. Biochimica Et Biophysica Acta. 1207: 93-101. PMID 7913833 DOI: 10.1016/0167-4838(94)90056-6  0.8
1994 Donovan GR, Street MD, Baldo BA, Alewood D, Alewood P, Sutherland S. Identification of an IgE-binding determinant of the major allergen Myr p I from the venom of the Australian jumper ant Myrmecia pilosula. Biochimica Et Biophysica Acta. 1204: 48-52. PMID 7508264 DOI: 10.1016/0167-4838(94)90031-0  0.8
1993 Nicholls IA, Morrison SF, Brinkworth RI, Alewood PF, Andrews PR. Central nervous system receptor binding profiles of some 2-amino-4-phenyl quinolines: a novel class of alpha 2-adrenoceptor selective ligands. Life Sciences. 53: PL343-7. PMID 8412517 DOI: 10.1016/0024-3205(93)90568-N  0.8
1993 Alewood PF, Bailey AJ, Brinkworth RI, Fairlie D, Jones A. Characterisation of TNF-alpha-related peptides by high-performance liquid chromatography-mass spectrometry and high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography. 646: 185-91. PMID 8408427 DOI: 10.1016/S0021-9673(99)87020-4  0.72
1993 Ball JB, Hughes RA, Alewood PF, Andrews PR. β-turn topography Tetrahedron. 49: 3467-3478. DOI: 10.1016/S0040-4020(01)90207-8  0.8
1992 Schnölzer M, Jones A, Alewood PF, Kent SB. Ion-spray tandem mass spectrometry in peptide synthesis: structural characterization of minor by-products in the synthesis of ACP(65-74). Analytical Biochemistry. 204: 335-43. PMID 1443533 DOI: 10.1016/0003-2697(92)90249-7  0.72
1990 Ball JB, Andrews PR, Alewood PF, Hughes RA. A one-variable topographical descriptor for the β-turns of peptides and proteins Febs Letters. 273: 15-18. PMID 2226846 DOI: 10.1016/0014-5793(90)81040-U  0.8
1990 Ball JB, Alewood PF. Conformational constraints: nonpeptide beta-turn mimics Journal of Molecular Recognition : Jmr. 3: 55-64. PMID 2163268 DOI: 10.1002/JMR.300030202  0.8
1989 Valerio RM, Perich JW, Kitas EA, Alewood PF, Johns RB. Synthesis of o-phosphotyrosine-containing peptides. II* solution-phase synthesis of asn-glu-PTyr-Thr-Ala through methyl phosphate protection Australian Journal of Chemistry. 42: 1519-1525. DOI: 10.1071/CH9891519  0.8
1987 Perich JW, Alewood PF, Johns RB. Synthesis of casein-related peptides and phosphopeptides. I Solution-Phase Synthesis and 13C N.M.R. Spectroscopy of the Nα-Acetyl Octapeptide N-methylamide corresponding to region 14-21 of bovine β-Casein A2 Australian Journal of Chemistry. 40: 257-271. DOI: 10.1071/CH9870257  0.8
1986 Johns RB, Alewood PF, Perich JW, Chaffee AL, MacLeod JK. Fast atom bombardment mass spectrometry of seryl- and O-phosphoseryl-containing peptides Tetrahedron Letters. 27: 4791-4794. DOI: 10.1016/S0040-4039(00)85066-2  0.8
1986 Perich JW, Alewood PF, Johns RB. Solution-phase synthesis of an O-phosphoseryl-containing peptide using phenyl phosphorotriester protection Tetrahedron Letters. 27: 1373-1376. DOI: 10.1016/S0040-4039(00)84262-8  0.8
1985 Alewood PF, Calder IC, Fernando R, Healey K, Richardson R. N-acetyl-N-oxo-1,4-benzoquinone imine, observation of an acyl nitrone Tetrahedron Letters. 26: 2467-2470. DOI: 10.1016/S0040-4039(00)94855-X  0.8
1984 Alewood PF, Perich JW, Johns RB. Preparation of nα-(t-butoxycarbonyl)-O-(dibenzylphosphono)-l-serine Australian Journal of Chemistry. 37: 429-433. DOI: 10.1071/CH9840429  0.8
1984 Alewood PF, Perich JW, Johns RB. A novel approach to phosphopeptide synthesis-preparation of glu-pser-leu Tetrahedron Letters. 25: 987-990. DOI: 10.1016/S0040-4039(01)80081-2  0.8
1982 Alewood PF, Perich JW, Johns RB. Synthesis of a Protected Phosphoamino Acid Nα-Teri-Butyloxycarbonyl-O-Diethylphosphoro-L-Serine Synthetic Communications. 12: 821-828. DOI: 10.1080/00397918208061923  0.8
1976 Jones AJ, Alewood PF, Benn M, Wong J. Functionalisation of the 4α-methyl group of lanostanol via azidoformate thermolysis Tetrahedron Letters. 17: 1655-1658. DOI: 10.1016/S0040-4039(00)92915-0  0.8
1973 Alewood PF, Kazmaier PM, Rauk A. Electronic structure of carbonyl nitrenes. Mechanism of insertion and abstraction reactions Journal of the American Chemical Society. 95: 5466-5475.  0.8
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