| Year |
Citation |
Score |
| 2019 |
Jin AH, Muttenthaler M, Dutertre S, Himaya SWA, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Conotoxins: Chemistry and Biology. Chemical Reviews. PMID 31633928 DOI: 10.1021/acs.chemrev.9b00207 |
0.92 |
|
| 2019 |
Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, ... ... Alewood PF, et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611414 DOI: 10.1073/pnas.1908662116 |
0.8 |
|
| 2019 |
Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. 160: 1766-1780. PMID 31335646 DOI: 10.1097/j.pain.0000000000001567 |
0.88 |
|
| 2019 |
Jin AH, Cristofori-Armstrong B, Rash LD, Román González SA, Espinosa RA, Lewis RJ, Alewood PF, Vetter I. Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels. Biochemical Pharmacology. PMID 31028742 DOI: 10.1016/j.bcp.2019.04.025 |
0.92 |
|
| 2019 |
Ziegman R, Undheim EAB, Baillie G, Jones A, Alewood PF. Investigation of the estuarine stonefish (Synanceia horrida) venom composition. Journal of Proteomics. PMID 30953730 DOI: 10.1016/j.jprot.2019.04.002 |
0.72 |
|
| 2019 |
Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. PMID 30908355 DOI: 10.1097/j.pain.0000000000001567 |
0.88 |
|
| 2019 |
Jin AH, Dutertre S, Dutt M, Lavergne V, Jones A, Lewis RJ, Alewood PF. Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, . Marine Drugs. 17. PMID 30893765 DOI: 10.3390/md17030177 |
0.92 |
|
| 2019 |
Ziegman R, Brust A, Jha P, Cardoso FC, Lewis RJ, Alewood PF. 'Messy' Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency. Marine Drugs. 17. PMID 30875751 DOI: 10.3390/md17030165 |
0.92 |
|
| 2019 |
Kakumanu R, Hodgson WC, Ravi R, Alagon A, Harris RJ, Brust A, Alewood PF, Kemp-Harper BK, Fry BG. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat () Blood Feeding. Toxins. 11. PMID 30626071 DOI: 10.3390/toxins11010026 |
0.76 |
|
| 2018 |
Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports. 8: 13397. PMID 30194442 DOI: 10.1038/s41598-018-31245-4 |
0.92 |
|
| 2018 |
Herzig V, de Araujo AD, Greenwood KP, Chin YK, Windley MJ, Chong Y, Muttenthaler M, Mobli M, Audsley N, Nicholson GM, Alewood PF, King GF. Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines. 6. PMID 30154370 DOI: 10.3390/biomedicines6030090 |
0.76 |
|
| 2018 |
Ma L, Chin YKY, Dekan Z, Herzig V, Yuen Chow C, Heighway J, Wing Lam S, Guillemin GJ, Alewood PF, King GF. Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochemical Pharmacology. PMID 30149017 DOI: 10.1016/j.bcp.2018.08.038 |
0.8 |
|
| 2018 |
Madio B, Peigneur S, Chin YKY, Hamilton BR, Henriques ST, Smith JJ, Cristofori-Armstrong B, Dekan Z, Boughton BA, Alewood PF, Tytgat J, King GF, Undheim EAB. PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences : Cmls. PMID 30109357 DOI: 10.1007/s00018-018-2897-6 |
0.8 |
|
| 2018 |
Ikonomopoulou MP, Fernandez-Rojo MA, Pineda SS, Cabezas-Sainz P, Winnen B, Morales RAV, Brust A, Sánchez L, Alewood PF, Ramm GA, Miles JJ, King GF. Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports. 8: 11519. PMID 30068931 DOI: 10.1038/s41598-018-29826-4 |
0.76 |
|
| 2018 |
Brust A, Wang CA, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Corrigendum: Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter. Angewandte Chemie (International Ed. in English). 57: 5203. PMID 29701320 DOI: 10.1002/anie.201803138 |
0.92 |
|
| 2018 |
Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP. Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery. 4: 19. PMID 29531816 DOI: 10.1038/s41420-018-0030-0 |
0.76 |
|
| 2017 |
Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, ... ... Alewood PF, et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 10. PMID 29208680 DOI: 10.1126/scisignal.aan3398 |
0.92 |
|
| 2017 |
Jin AH, Dekan Z, Smout MJ, Wilson D, Dutertre S, Vetter I, Lewis RJ, Loukas A, Daly NL, Alewood PF. Conotoxin Φ-MiXXVIIA from the new superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie (International Ed. in English). PMID 28984021 DOI: 10.1002/anie.201708927 |
0.92 |
|
| 2017 |
Sousa SR, Wingerd JS, Brust A, Bladen C, Ragnarsson L, Herzig V, Deuis JR, Dutertre S, Vetter I, Zamponi GW, King GF, Alewood PF, Lewis RJ. Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. Plos One. 12: e0182848. PMID 28880874 DOI: 10.1371/journal.pone.0182848 |
0.92 |
|
| 2017 |
Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 46816. PMID 28548111 DOI: 10.1038/srep46816 |
0.92 |
|
| 2017 |
Cardoso FC, Dekan Z, Smith JJ, Deuis JR, Vetter I, Herzig V, Alewood PF, King GF, Lewis RJ. Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology. PMID 28542706 DOI: 10.1111/bph.13865 |
0.92 |
|
| 2017 |
Dekan Z, Heady SJ, Scanlon M, Baldo BA, Lee TH, Aguilar MI, Deuis JR, Vetter I, Elliott AG, Amado M, Cooper MA, Alewood D, Alewood PF. Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the Jack Jumper ant with antimicrobial, membrane disrupting and nociceptive activities. Angewandte Chemie (International Ed. in English). PMID 28513074 DOI: 10.1002/anie.201703360 |
0.88 |
|
| 2017 |
Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/s41598-017-01129-0 |
0.92 |
|
| 2017 |
Abraham N, Healy M, Ragnarsson L, Brust A, Alewood PF, Lewis RJ. Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor. Scientific Reports. 7: 45466. PMID 28361878 DOI: 10.1038/srep45466 |
0.92 |
|
| 2017 |
Di Giglio MG, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T, Rattei T, Arrowsmith S, Wray S, Marek A, Elbert T, Alewood PF, Gloriam DE, Gruber CW. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. 7: 41002. PMID 28145450 DOI: 10.1038/srep41002 |
0.76 |
|
| 2017 |
Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/srep40883 |
0.92 |
|
| 2016 |
Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon : Official Journal of the International Society On Toxinology. PMID 27793656 DOI: 10.1016/j.toxicon.2016.10.013 |
0.88 |
|
| 2016 |
Yang DC, Deuis JR, Dashevsky D, Dobson J, Jackson TN, Brust A, Xie B, Koludarov I, Debono J, Hendrikx I, Hodgson WC, Josh P, Nouwens A, Baillie GJ, Bruxner TJ, ... Alewood PF, et al. The Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus). Toxins. 8. PMID 27763551 DOI: 10.3390/toxins8100303 |
0.88 |
|
| 2016 |
Touchard A, Brust A, Cardoso FC, Chin YK, Herzig V, Jin AH, Dejean A, Alewood PF, King GF, Orivel J, Escoubas P. Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica Et Biophysica Acta. PMID 27474999 DOI: 10.1016/j.bbagen.2016.07.027 |
0.92 |
|
| 2016 |
Deuis JR, Dekan Z, Inserra MC, Lee TH, Aguilar MI, Craik DJ, Lewis RJ, Alewood PF, Mobli M, Schroeder CI, Henriques ST, Vetter I. Development of a μO-conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Target NaV1.8. The Journal of Biological Chemistry. PMID 27026701 DOI: 10.1074/jbc.M116.721662 |
0.92 |
|
| 2016 |
Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I. Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain. Toxins. 8. PMID 26999206 DOI: 10.3390/toxins8030078 |
0.92 |
|
| 2016 |
Wan J, Alewood PF. Peptide-Decorated Dendrimers and Their Bioapplications. Angewandte Chemie (International Ed. in English). PMID 26990715 DOI: 10.1002/anie.201508428 |
0.92 |
|
| 2016 |
Wan J, Brust A, Bhola RF, Jha P, Mobli M, Lewis RJ, Christie MJ, Alewood PF. Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 26910400 DOI: 10.1002/psc.2857 |
0.92 |
|
| 2016 |
Brust A, Croker DE, Colless B, Ragnarsson L, Andersson A, Jain K, Caraballo SG, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-derived κ-opioid agonists (conorphins): potent, selective and metabolic stable dynorphinA mimetics with anti-nociceptive properties. Journal of Medicinal Chemistry. PMID 26859603 DOI: 10.1021/acs.jmedchem.5b00911 |
0.92 |
|
| 2015 |
Reeks T, Lavergne V, Sunagar K, Jones A, Undheim E, Dunstan N, Fry B, Alewood PF. Deep venomics of the Pseudonaja genus reveals inter- and intra-specific variation. Journal of Proteomics. PMID 26632978 DOI: 10.1016/j.jprot.2015.11.019 |
0.92 |
|
| 2015 |
Jin AH, Vetter I, Himaya SW, Alewood PF, Lewis RJ, Dutertre S. Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom. Proteomics. PMID 26506909 DOI: 10.1002/pmic.201500220 |
0.92 |
|
| 2015 |
Himaya SW, Jin AH, Dutertre S, Giacomotto J, Mohialdeen H, Vetter I, Alewood PF, Lewis RJ. Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research. 14: 4372-81. PMID 26322961 DOI: 10.1021/acs.jproteome.5b00630 |
0.92 |
|
| 2015 |
Deuis JR, Whately E, Brust A, Inserra MC, Asvadi NH, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. Acs Chemical Neuroscience. 6: 1751-8. PMID 26225903 DOI: 10.1021/acschemneuro.5b00113 |
0.92 |
|
| 2015 |
Jin AH, Israel MR, Inserra MC, Smith JJ, Lewis RJ, Alewood PF, Vetter I, Dutertre S. δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings. Biological Sciences / the Royal Society. 282. PMID 26156767 DOI: 10.1098/rspb.2015.0817 |
0.92 |
|
| 2015 |
Lavergne V, Harliwong I, Jones A, Miller D, Taft RJ, Alewood PF. Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks. Proceedings of the National Academy of Sciences of the United States of America. 112: E3782-91. PMID 26150494 DOI: 10.1073/pnas.1501334112 |
0.72 |
|
| 2015 |
Jouiaei M, Yanagihara AA, Madio B, Nevalainen TJ, Alewood PF, Fry BG. Ancient Venom Systems: A Review on Cnidaria Toxins. Toxins. 7: 2251-71. PMID 26094698 DOI: 10.3390/toxins7062251 |
0.92 |
|
| 2015 |
Cardoso FC, Dekan Z, Rosengren KJ, Erickson A, Vetter I, Deuis JR, Herzig V, Alewood PF, King GF, Lewis RJ. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Molecular Pharmacology. 88: 291-303. PMID 25979003 DOI: 10.1124/mol.115.098178 |
0.92 |
|
| 2015 |
Jouiaei M, Sunagar K, Federman Gross A, Scheib H, Alewood PF, Moran Y, Fry BG. Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemone. Molecular Biology and Evolution. 32: 1598-610. PMID 25757852 DOI: 10.1093/molbev/msv050 |
0.92 |
|
| 2015 |
Reeks T, Jones A, Brust A, Sridharan S, Corcilius L, Wilkinson BL, Thaysen-Andersen M, Payne RJ, Kini RM, Daly NL, Alewood PF. A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie (International Ed. in English). 54: 4828-31. PMID 25735823 DOI: 10.1002/anie.201411914 |
0.92 |
|
| 2015 |
Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/jacs.5b00244 |
0.92 |
|
| 2015 |
Mueller A, Starobova H, Inserra MC, Jin AH, Deuis JR, Dutertre S, Lewis RJ, Alewood PF, Daly NL, Vetter I. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology. 94: 155-63. PMID 25646788 DOI: 10.1016/j.bcp.2015.01.011 |
0.92 |
|
| 2015 |
Murali SS, Napier IA, Mohammadi SA, Alewood PF, Lewis RJ, Christie MJ. High-voltage-activated calcium current subtypes in mouse DRG neurons adapt in a subpopulation-specific manner after nerve injury. Journal of Neurophysiology. 113: 1511-9. PMID 25505111 DOI: 10.1152/jn.00608.2014 |
0.92 |
|
| 2015 |
Gori A, Wang CI, Harvey PJ, Rosengren KJ, Bhola RF, Gelmi ML, Longhi R, Christie MJ, Lewis RJ, Alewood PF, Brust A. Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic. Angewandte Chemie (International Ed. in English). 54: 1361-4. PMID 25483297 DOI: 10.1002/anie.201409678 |
0.92 |
|
| 2014 |
Prashanth JR, Brust A, Jin AH, Alewood PF, Dutertre S, Lewis RJ. Cone snail venomics: from novel biology to novel therapeutics. Future Medicinal Chemistry. 6: 1659-75. PMID 25406006 DOI: 10.4155/fmc.14.99 |
0.92 |
|
| 2014 |
Jensen JE, Cristofori-Armstrong B, Anangi R, Rosengren KJ, Lau CH, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores. Journal of Medicinal Chemistry. 57: 9195-203. PMID 25337890 DOI: 10.1021/jm501400p |
0.76 |
|
| 2014 |
Dutertre S, Jin AH, Alewood PF, Lewis RJ. Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose. Toxicon : Official Journal of the International Society On Toxinology. 91: 135-44. PMID 25301479 DOI: 10.1016/j.toxicon.2014.09.011 |
0.92 |
|
| 2014 |
Vink S, Daly NL, Steen N, Craik DJ, Alewood PF. Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon : Official Journal of the International Society On Toxinology. 90: 308-17. PMID 25172536 DOI: 10.1016/j.toxicon.2014.08.068 |
0.92 |
|
| 2014 |
Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42. PMID 25101833 DOI: 10.1016/j.bcp.2014.07.025 |
0.92 |
|
| 2014 |
Wang CI, Reeks T, Vetter I, Vergara I, Kovtun O, Lewis RJ, Alewood PF, Durek T. Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry. 53: 3758-66. PMID 24867092 DOI: 10.1021/bi5004475 |
0.92 |
|
| 2014 |
Akondi KB, Muttenthaler M, Dutertre S, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Discovery, synthesis, and structure-activity relationships of conotoxins. Chemical Reviews. 114: 5815-47. PMID 24720541 DOI: 10.1021/cr400401e |
0.92 |
|
| 2014 |
Deuis JR, Lim YL, Rodrigues de Sousa S, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology. 16: 1324-32. PMID 24714523 DOI: 10.1093/neuonc/nou048 |
0.92 |
|
| 2014 |
Dutertre S, Jin AH, Vetter I, Hamilton B, Sunagar K, Lavergne V, Dutertre V, Fry BG, Antunes A, Venter DJ, Alewood PF, Lewis RJ. Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications. 5: 3521. PMID 24662800 DOI: 10.1038/ncomms4521 |
0.92 |
|
| 2014 |
Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie (International Ed. in English). 53: 2931-4. PMID 24604812 DOI: 10.1002/anie.201310103 |
0.92 |
|
| 2014 |
Brust A, Schroeder CI, Alewood PF. High-throughput synthesis of peptide α-thioesters: a safety catch linker approach enabling parallel hydrogen fluoride cleavage. Chemmedchem. 9: 1038-46. PMID 24591329 DOI: 10.1002/cmdc.201300524 |
0.76 |
|
| 2014 |
Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochemical Pharmacology. 89: 276-86. PMID 24561180 DOI: 10.1016/j.bcp.2014.02.008 |
0.92 |
|
| 2014 |
Gui J, Liu B, Cao G, Lipchik AM, Perez M, Dekan Z, Mobli M, Daly NL, Alewood PF, Parker LL, King GF, Zhou Y, Jordt SE, Nitabach MN. A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology : Cb. 24: 473-83. PMID 24530065 DOI: 10.1016/j.cub.2014.01.013 |
0.92 |
|
| 2014 |
de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications. 5: 3165. PMID 24476666 DOI: 10.1038/ncomms4165 |
0.92 |
|
| 2014 |
Jin AH, Vetter I, Dutertre S, Abraham N, Emidio NB, Inserra M, Murali SS, Christie MJ, Alewood PF, Lewis RJ. MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors. Biochemistry. 53: 1-3. PMID 24351107 DOI: 10.1021/bi400882s |
0.92 |
|
| 2014 |
Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie (International Ed. in English). 53: 1017-20. PMID 24323786 DOI: 10.1002/anie.201308898 |
0.92 |
|
| 2013 |
Sadeghi M, Murali SS, Lewis RJ, Alewood PF, Mohammadi S, Christie MJ. Novel ω-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration. Molecular Pain. 9: 51. PMID 24139484 DOI: 10.1186/1744-8069-9-51 |
0.92 |
|
| 2013 |
Lavergne V, Dutertre S, Jin AH, Lewis RJ, Taft RJ, Alewood PF. Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. Bmc Genomics. 14: 708. PMID 24131469 DOI: 10.1186/1471-2164-14-708 |
0.92 |
|
| 2013 |
Brust A, Wang CI, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Ed. in English). 52: 12020-3. PMID 24115503 DOI: 10.1002/anie.201304660 |
0.92 |
|
| 2013 |
Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/jbc.M113.512582 |
0.92 |
|
| 2013 |
Jin AH, Dutertre S, Kaas Q, Lavergne V, Kubala P, Lewis RJ, Alewood PF. Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Molecular & Cellular Proteomics : McP. 12: 3824-33. PMID 24043424 DOI: 10.1074/mcp.M113.030353 |
0.92 |
|
| 2013 |
Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/j.bcp.2013.07.016 |
0.92 |
|
| 2013 |
Ruder T, Ali SA, Ormerod K, Brust A, Roymanchadi ML, Ventura S, Undheim EA, Jackson TN, Mercier AJ, King GF, Alewood PF, Fry BG. Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides. 47: 71-6. PMID 23850991 DOI: 10.1016/j.peptides.2013.07.002 |
0.92 |
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| 2013 |
Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. Quantification of lactosylation of whey proteins in stored milk powder using multiple reaction monitoring. Food Chemistry. 141: 1203-10. PMID 23790905 DOI: 10.1016/j.foodchem.2013.03.073 |
0.92 |
|
| 2013 |
Smith JJ, Vetter I, Lewis RJ, Peigneur S, Tytgat J, Lam A, Gallant EM, Beard NA, Alewood PF, Dulhunty AF. Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins. Proceedings of the National Academy of Sciences of the United States of America. 110: 8906-11. PMID 23671114 DOI: 10.1073/pnas.1214062110 |
0.92 |
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| 2013 |
de Araujo AD, Herzig V, Windley MJ, Dziemborowicz S, Mobli M, Nicholson GM, Alewood PF, King GF. Do vicinal disulfide bridges mediate functionally important redox transformations in proteins? Antioxidants & Redox Signaling. 19: 1976-80. PMID 23646911 DOI: 10.1089/ars.2013.5365 |
0.76 |
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| 2013 |
Ghassemian A, Vila-Farrés X, Alewood PF, Durek T. Solid phase synthesis of peptide-selenoesters. Bioorganic & Medicinal Chemistry. 21: 3473-8. PMID 23608106 DOI: 10.1016/j.bmc.2013.03.076 |
0.88 |
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| 2013 |
Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. Acs Chemical Biology. 8: 1215-22. PMID 23527544 DOI: 10.1021/cb400012k |
0.92 |
|
| 2013 |
Smith JJ, Herzig V, King GF, Alewood PF. The insecticidal potential of venom peptides. Cellular and Molecular Life Sciences : Cmls. 70: 3665-93. PMID 23525661 DOI: 10.1007/s00018-013-1315-3 |
0.68 |
|
| 2013 |
Ghassemian A, Wang CI, Yau MK, Reid RC, Lewis RJ, Fairlie DP, Alewood PF, Durek T. Efficient chemical synthesis of human complement protein C3a. Chemical Communications (Cambridge, England). 49: 2356-8. PMID 23407800 DOI: 10.1039/c3cc40537k |
0.92 |
|
| 2013 |
Brust A, Sunagar K, Undheim EA, Vetter I, Yang DC, Yang DC, Casewell NR, Jackson TN, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, et al. Differential evolution and neofunctionalization of snake venom metalloprotease domains. Molecular & Cellular Proteomics : McP. 12: 651-63. PMID 23242553 DOI: 10.1074/mcp.M112.023135 |
0.92 |
|
| 2013 |
Dutertre S, Jin AH, Kaas Q, Jones A, Alewood PF, Lewis RJ. Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Molecular & Cellular Proteomics : McP. 12: 312-29. PMID 23152539 DOI: 10.1074/mcp.M112.021469 |
0.92 |
|
| 2012 |
Smith JJ, Jones A, Alewood PF. Mass landscapes of seven scorpion species: The first analyses of Australian species with 1,5-DAN matrix. Journal of Venom Research. 3: 7-14. PMID 23236582 |
0.72 |
|
| 2012 |
Schroeder CI, Nielsen KJ, Adams DA, Loughnan M, Thomas L, Alewood PF, Lewis RJ, Craik DJ. Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers. 98: 345-56. PMID 23193599 |
0.92 |
|
| 2012 |
de Araujo AD, Mobli M, King GF, Alewood PF. Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie (International Ed. in English). 51: 10298-302. PMID 22991244 DOI: 10.1002/anie.201204229 |
0.76 |
|
| 2012 |
Jensen JE, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3. Marine Drugs. 10: 1511-27. PMID 22851922 DOI: 10.3390/md10071511 |
0.76 |
|
| 2012 |
Lavergne V, Taft RJ, Alewood PF. Cysteine-rich mini-proteins in human biology. Current Topics in Medicinal Chemistry. 12: 1514-33. PMID 22827521 |
0.44 |
|
| 2012 |
Schroeder CI, Adams D, Thomas L, Alewood PF, Lewis RJ. N- and C-terminal extensions of μ-conotoxins increase potency and selectivity for neuronal sodium channels. Biopolymers. 98: 161-5. PMID 22733528 DOI: 10.1002/bip.22032 |
0.92 |
|
| 2012 |
Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochemical Pharmacology. 84: 540-8. PMID 22609441 DOI: 10.1016/j.bcp.2012.05.008 |
0.92 |
|
| 2012 |
Dekan Z, Wang CI, Andrews RK, Lewis RJ, Alewood PF. Conotoxin engineering: dual pharmacophoric noradrenaline transport inhibitor/integrin binding peptide with improved stability. Organic & Biomolecular Chemistry. 10: 5791-4. PMID 22581211 DOI: 10.1039/c2ob25133g |
0.92 |
|
| 2012 |
Vetter I, Mozar CA, Durek T, Wingerd JS, Alewood PF, Christie MJ, Lewis RJ. Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells. Biochemical Pharmacology. 83: 1562-71. PMID 22410003 DOI: 10.1016/j.bcp.2012.02.022 |
0.92 |
|
| 2012 |
Beaumont KA, Smit DJ, Liu YY, Chai E, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Sturm RA. Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. Pigment Cell & Melanoma Research. 25: 370-4. PMID 22364200 DOI: 10.1111/j.1755-148X.2012.00990.x |
0.92 |
|
| 2012 |
Hjørringgaard CU, Brust A, Alewood PF. Evaluation of COMU as a coupling reagent for in situ neutralization Boc solid phase peptide synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 199-207. PMID 22252935 DOI: 10.1002/psc.1438 |
0.76 |
|
| 2012 |
Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marà F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/j.bcp.2011.11.006 |
0.92 |
|
| 2011 |
Muttenthaler M, Akondi KB, Alewood PF. Structure-activity studies on alpha-conotoxins. Current Pharmaceutical Design. 17: 4226-41. PMID 22204424 |
0.76 |
|
| 2011 |
de Araujo AD, Christensen C, Buchardt J, Kent SB, Alewood PF. Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 13983-6. PMID 22084036 DOI: 10.1002/chem.201102732 |
0.56 |
|
| 2011 |
Mobli M, Morgenstern D, King GF, Alewood PF, Muttenthaler M. Site-specific pK(a) determination of selenocysteine residues in selenovasopressin by using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 50: 11952-5. PMID 22002840 DOI: 10.1002/anie.201104169 |
0.76 |
|
| 2011 |
Durek T, Alewood PF. Preformed selenoesters enable rapid native chemical ligation at intractable sites. Angewandte Chemie (International Ed. in English). 50: 12042-5. PMID 21997950 DOI: 10.1002/anie.201105512 |
0.88 |
|
| 2011 |
Dekan Z, Vetter I, Daly NL, Craik DJ, Lewis RJ, Alewood PF. α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society. 133: 15866-9. PMID 21899353 DOI: 10.1021/ja206408q |
0.92 |
|
| 2011 |
Smith JJ, Hill JM, Little MJ, Nicholson GM, King GF, Alewood PF. Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif. Proceedings of the National Academy of Sciences of the United States of America. 108: 10478-83. PMID 21670253 DOI: 10.1073/pnas.1103501108 |
0.68 |
|
| 2011 |
de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/anie.201101642 |
0.92 |
|
| 2011 |
Wijffels G, Johnson WM, Oakley AJ, Turner K, Epa VC, Briscoe SJ, Polley M, Liepa AJ, Hofmann A, Buchardt J, Christensen C, Prosselkov P, Dalrymple BP, Alewood PF, Jennings PA, et al. Binding inhibitors of the bacterial sliding clamp by design. Journal of Medicinal Chemistry. 54: 4831-8. PMID 21604761 DOI: 10.1021/jm2004333 |
0.92 |
|
| 2011 |
Holland JW, Gupta R, Deeth HC, Alewood PF. Proteomic analysis of temperature-dependent changes in stored UHT milk Journal of Agricultural and Food Chemistry. 59: 1837-1846. PMID 21322568 DOI: 10.1021/jf104395v |
0.92 |
|
| 2011 |
Beaumont KA, Wong SS, Ainger SA, Liu YY, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Leonard JH, Sturm RA. Melanocortin MC1 receptor in human genetics and model systems European Journal of Pharmacology. 660: 103-110. PMID 21199646 DOI: 10.1016/j.ejphar.2010.11.040 |
0.92 |
|
| 2011 |
Rash LD, Morales RA, Vink S, Alewood PF. De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina). Toxicon : Official Journal of the International Society On Toxinology. 57: 208-16. PMID 21115026 DOI: 10.1016/j.toxicon.2010.11.012 |
0.52 |
|
| 2011 |
Vetter I, Davis JL, Rash LD, Anangi R, Mobli M, Alewood PF, Lewis RJ, King GF. Venomics: A new paradigm for natural products-based drug discovery Amino Acids. 40: 15-28. PMID 20177945 DOI: 10.1007/s00726-010-0516-4 |
0.92 |
|
| 2010 |
Muttenthaler M, Andersson A, de Araujo AD, Dekan Z, Lewis RJ, Alewood PF. Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of Medicinal Chemistry. 53: 8585-96. PMID 21117646 DOI: 10.1021/jm100989w |
0.92 |
|
| 2010 |
Alewood D, Hopping G, Brust A, Reid RC, Alewood PF. Benzhydrylamine linker grafting: a strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 551-7. PMID 20862722 DOI: 10.1002/psc.1248 |
0.92 |
|
| 2010 |
Morales RA, Daly NL, Vetter I, Mobli M, Napier IA, Craik DJ, Lewis RJ, Christie MJ, King GF, Alewood PF, Durek T. Chemical synthesis and structure of the prokineticin Bv8. Chembiochem : a European Journal of Chemical Biology. 11: 1882-8. PMID 20677202 DOI: 10.1002/cbic.201000330 |
0.92 |
|
| 2010 |
Muttenthaler M, Ramos YG, Feytens D, de Araujo AD, Alewood PF. p-Nitrobenzyl protection for cysteine and selenocysteine: a more stable alternative to the acetamidomethyl group. Biopolymers. 94: 423-32. PMID 20593464 DOI: 10.1002/bip.21502 |
0.76 |
|
| 2010 |
Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 285: 22254-63. PMID 20466726 DOI: 10.1074/jbc.M110.111880 |
0.92 |
|
| 2010 |
Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22. PMID 20163143 DOI: 10.1021/ja910602h |
0.92 |
|
| 2010 |
Luo S, Akondi KB, Zhangsun D, Wu Y, Zhu X, Hu Y, Christensen S, Dowell C, Daly NL, Craik DJ, Wang CIA, Lewis RJ, Alewood PF, McIntosh JM. Atypical α-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor Journal of Biological Chemistry. 285: 12355-12366. PMID 20145249 DOI: 10.1074/jbc.M109.079012 |
0.92 |
|
| 2010 |
Armishaw CJ, Dutton JL, Craik DJ, Alewood PF. Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogs. Biopolymers. 94: 307-13. PMID 20013812 DOI: 10.1002/bip.21360 |
0.92 |
|
| 2009 |
Mobli M, de Araújo AD, Lambert LK, Pierens GK, Windley MJ, Nicholson GM, Alewood PF, King GF. Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 48: 9312-4. PMID 19890933 DOI: 10.1002/anie.200905206 |
0.76 |
|
| 2009 |
Brust A, Palant E, Croker DE, Colless B, Drinkwater R, Patterson B, Schroeder CI, Wilson D, Nielsen CK, Smith MT, Alewood D, Alewood PF, Lewis RJ. chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry. 52: 6991-7002. PMID 19860431 DOI: 10.1021/jm9003413 |
0.92 |
|
| 2009 |
Vernall AJ, Cassidy P, Alewood PF. A single alpha-helical turn stabilized by replacement of an internal hydrogen bond with a covalent ethylene bridge. Angewandte Chemie (International Ed. in English). 48: 5675-8. PMID 19562809 DOI: 10.1002/anie.200901059 |
0.92 |
|
| 2009 |
Ueberheide BM, Fenyö D, Alewood PF, Chait BT. Rapid sensitive analysis of cysteine rich peptide venom components. Proceedings of the National Academy of Sciences of the United States of America. 106: 6910-5. PMID 19380747 DOI: 10.1073/pnas.0900745106 |
0.92 |
|
| 2009 |
Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon. 54: 56-61. PMID 19306891 DOI: 10.1016/j.toxicon.2009.03.014 |
0.92 |
|
| 2009 |
Pages G, Torres AM, Ju P, Bansal PS, Alewood PF, Kuchel PW, Vandenberg JI. Structure of the pore-helix of the hERG K(+) channel. European Biophysics Journal : Ebj. 39: 111-20. PMID 19305991 DOI: 10.1007/s00249-009-0433-1 |
0.4 |
|
| 2009 |
Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/jbc.M804950200 |
0.92 |
|
| 2008 |
Muttenthaler M, Alewood PF. Selenopeptide chemistry. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 1223-39. PMID 18951416 DOI: 10.1002/psc.1075 |
0.76 |
|
| 2008 |
Poth AG, Deeth HC, Alewood PF, Holland JW. Analysis of the human casein phosphoproteome by 2-D electrophoresis and MALDI-TOF/TOF MS reveals new phosphoforms Journal of Proteome Research. 7: 5017-5027. PMID 18847231 DOI: 10.1021/pr800387s |
0.92 |
|
| 2008 |
Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84. PMID 18754612 DOI: 10.1021/jm800278k |
0.92 |
|
| 2008 |
Holland JW, Deeth HC, Alewood PF. Analysis of disulphide linkages in bovine κ-casein oligomers using two-dimensional electrophoresis Electrophoresis. 29: 2402-2410. PMID 18548457 DOI: 10.1002/elps.200700840 |
0.92 |
|
| 2008 |
Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. The Journal of Biological Chemistry. 283: 21621-8. PMID 18522941 DOI: 10.1074/jbc.M802852200 |
0.92 |
|
| 2007 |
Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28 |
0.92 |
|
| 2007 |
Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Molecular Pharmacology. 71: 676-85. PMID 17142296 DOI: 10.1124/mol.106.028225 |
0.92 |
|
| 2006 |
Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/jbc.M603703200 |
0.92 |
|
| 2006 |
Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists Journal of Biological Chemistry. 281: 14136-14143. PMID 16500898 DOI: 10.1074/jbc.M512419200 |
0.92 |
|
| 2004 |
Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/jm031010o |
0.92 |
|
| 2003 |
Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. The Journal of Biological Chemistry. 278: 40317-23. PMID 12885787 DOI: 10.1074/jbc.M213030200 |
0.92 |
|
| 2003 |
Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of Biological Chemistry. 278: 34451-7. PMID 12824165 DOI: 10.1074/jbc.M305410200 |
0.92 |
|
| 2003 |
Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/jbc.M212628200 |
0.92 |
|
| 2003 |
Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. Journal of Medicinal Chemistry. 46: 1266-72. PMID 12646037 DOI: 10.1021/jm020426j |
0.92 |
|
| 2003 |
Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/jbc.M210280200 |
0.92 |
|
| 2002 |
Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. The Journal of Biological Chemistry. 277: 48849-57. PMID 12376538 DOI: 10.1074/jbc.M208842200 |
0.92 |
|
| 2002 |
Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. The Journal of Biological Chemistry. 277: 27247-55. PMID 12006587 DOI: 10.1074/jbc.M201611200 |
0.92 |
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