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Paul F. Alewood - Publications

Affiliations: 
IMB University of Queensland, Saint Lucia, Queensland, Australia 
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Year Citation  Score
2022 Wilhelm P, Luna-Ramirez K, Chin YK, Dekan Z, Abraham N, Tae HS, Chow CY, Eagles DA, King GF, Lewis RJ, Adams DJ, Alewood PF. Cysteine-Rich α-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor. Acs Chemical Neuroscience. PMID 35357806 DOI: 10.1021/acschemneuro.1c00857  0.393
2022 Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, ... ... Alewood PF, et al. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35074873 DOI: 10.1073/pnas.2110932119  0.41
2021 Tae HS, Gao B, Jin AH, Alewood PF, Adams DJ. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors. Biochemical Pharmacology. 114638. PMID 34062129 DOI: 10.1016/j.bcp.2021.114638  0.346
2021 Walker AA, Robinson SD, Paluzzi JV, Merritt DJ, Nixon SA, Schroeder CI, Jin J, Goudarzi MH, Kotze AC, Dekan Z, Sombke A, Alewood PF, Fry BG, Epstein ME, Vetter I, et al. Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33893140 DOI: 10.1073/pnas.2023815118  0.305
2021 Muttenthaler M, King GF, Adams DJ, Alewood PF. Trends in peptide drug discovery. Nature Reviews. Drug Discovery. PMID 33536635 DOI: 10.1038/s41573-020-00135-8  0.429
2020 Herzig V, Sunagar K, Wilson DTR, Pineda SS, Israel MR, Dutertre S, McFarland BS, Undheim EAB, Hodgson WC, Alewood PF, Lewis RJ, Bosmans F, Vetter I, King GF, Fry BG. Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958636 DOI: 10.1073/Pnas.2004516117  0.32
2020 Fernandez-Rojo MA, Brust A, Potriquet J, Daley J, Ragnarsson L, Andersson A, Mukhopadhyay P, Wilhelm P, Chin Y, Smallwood T, Clark R, King G, Ramm G, Waddell N, Lewis R, ... ... Alewood P, et al. The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation. Toxicon : Official Journal of the International Society On Toxinology. 177: S2. PMID 32634945 DOI: 10.1016/J.Toxicon.2019.10.014  0.339
2020 Nixon SA, Dekan Z, Robinson SD, Guo S, Vetter I, Kotze AC, Alewood PF, King GF, Herzig V. It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant . Biomedicines. 8. PMID 32629771 DOI: 10.3390/Biomedicines8070185  0.377
2020 Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF. Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target Na1.7. Biochemical Pharmacology. 114080. PMID 32511987 DOI: 10.1016/J.Bcp.2020.114080  0.363
2020 Muttenthaler M, Nevin ST, Inserra M, Lewis RJ, Adams DJ, Alewood P. On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. Australian Journal of Chemistry. 73: 327-333. PMID 32394983 DOI: 10.1071/Ch19456  0.52
2020 Yin K, Deuis JR, Dekan Z, Jin AH, Alewood PF, King GF, Herzig V, Vetter I. Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of Na1.7. Biomedicines. 8. PMID 32092883 DOI: 10.3390/Biomedicines8020037  0.422
2020 Himaya SWA, Rai SK, Pamfili G, Jin A, Alewood PF, Lewis RJ. Venomic Interrogation Reveals the Complexity of Conus striolatus Venom Australian Journal of Chemistry. 73: 357-365. DOI: 10.1071/Ch19588  0.363
2019 Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic acetylcholine receptors. British Journal of Pharmacology. PMID 31877243 DOI: 10.1111/Bph.14954  0.465
2019 Dutt M, Giacomotto J, Ragnarsson L, Andersson Å, Brust A, Dekan Z, Alewood PF, Lewis RJ. The α-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa. Scientific Reports. 9: 17841. PMID 31780714 DOI: 10.1038/S41598-019-54186-Y  0.383
2019 Jin AH, Muttenthaler M, Dutertre S, Himaya SWA, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Conotoxins: Chemistry and Biology. Chemical Reviews. PMID 31633928 DOI: 10.1021/Acs.Chemrev.9B00207  0.43
2019 Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, ... ... Alewood PF, et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611414 DOI: 10.1073/Pnas.1908662116  0.326
2019 Jin AH, Cristofori-Armstrong B, Rash LD, Román González SA, Espinosa RA, Lewis RJ, Alewood PF, Vetter I. Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels. Biochemical Pharmacology. PMID 31028742 DOI: 10.1016/J.Bcp.2019.04.025  0.427
2019 Jin AH, Dutertre S, Dutt M, Lavergne V, Jones A, Lewis RJ, Alewood PF. Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, . Marine Drugs. 17. PMID 30893765 DOI: 10.3390/Md17030177  0.333
2019 Ziegman R, Brust A, Jha P, Cardoso FC, Lewis RJ, Alewood PF. 'Messy' Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency. Marine Drugs. 17. PMID 30875751 DOI: 10.3390/Md17030165  0.399
2019 Kakumanu R, Hodgson WC, Ravi R, Alagon A, Harris RJ, Brust A, Alewood PF, Kemp-Harper BK, Fry BG. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat () Blood Feeding. Toxins. 11. PMID 30626071 DOI: 10.3390/Toxins11010026  0.372
2018 Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports. 8: 13397. PMID 30194442 DOI: 10.1038/S41598-018-31245-4  0.484
2018 Herzig V, de Araujo AD, Greenwood KP, Chin YK, Windley MJ, Chong Y, Muttenthaler M, Mobli M, Audsley N, Nicholson GM, Alewood PF, King GF. Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines. 6. PMID 30154370 DOI: 10.3390/Biomedicines6030090  0.403
2018 Ma L, Chin YKY, Dekan Z, Herzig V, Yuen Chow C, Heighway J, Wing Lam S, Guillemin GJ, Alewood PF, King GF. Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochemical Pharmacology. PMID 30149017 DOI: 10.1016/J.Bcp.2018.08.038  0.42
2018 Madio B, Peigneur S, Chin YKY, Hamilton BR, Henriques ST, Smith JJ, Cristofori-Armstrong B, Dekan Z, Boughton BA, Alewood PF, Tytgat J, King GF, Undheim EAB. PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences : Cmls. PMID 30109357 DOI: 10.1007/S00018-018-2897-6  0.424
2018 Ikonomopoulou MP, Fernandez-Rojo MA, Pineda SS, Cabezas-Sainz P, Winnen B, Morales RAV, Brust A, Sánchez L, Alewood PF, Ramm GA, Miles JJ, King GF. Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports. 8: 11519. PMID 30068931 DOI: 10.1038/s41598-018-29826-4  0.335
2018 Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP. Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery. 4: 19. PMID 29531816 DOI: 10.1038/S41420-018-0030-0  0.347
2017 Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, ... ... Alewood PF, et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 10. PMID 29208680 DOI: 10.1126/Scisignal.Aan3398  0.305
2017 Jin AH, Dekan Z, Smout MJ, Wilson D, Dutertre S, Vetter I, Lewis RJ, Loukas A, Daly NL, Alewood PF. Conotoxin Φ-MiXXVIIA from the new superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie (International Ed. in English). PMID 28984021 DOI: 10.1002/Anie.201708927  0.449
2017 Sousa SR, Wingerd JS, Brust A, Bladen C, Ragnarsson L, Herzig V, Deuis JR, Dutertre S, Vetter I, Zamponi GW, King GF, Alewood PF, Lewis RJ. Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. Plos One. 12: e0182848. PMID 28880874 DOI: 10.1371/Journal.Pone.0182848  0.372
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 46816. PMID 28548111 DOI: 10.1038/Srep46816  0.34
2017 Cardoso FC, Dekan Z, Smith JJ, Deuis JR, Vetter I, Herzig V, Alewood PF, King GF, Lewis RJ. Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology. PMID 28542706 DOI: 10.1111/Bph.13865  0.301
2017 Dekan Z, Heady SJ, Scanlon M, Baldo BA, Lee TH, Aguilar MI, Deuis JR, Vetter I, Elliott AG, Amado M, Cooper MA, Alewood D, Alewood PF. Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the Jack Jumper ant with antimicrobial, membrane disrupting and nociceptive activities. Angewandte Chemie (International Ed. in English). PMID 28513074 DOI: 10.1002/Anie.201703360  0.373
2017 Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/S41598-017-01129-0  0.468
2017 Abraham N, Healy M, Ragnarsson L, Brust A, Alewood PF, Lewis RJ. Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor. Scientific Reports. 7: 45466. PMID 28361878 DOI: 10.1038/Srep45466  0.358
2017 Di Giglio MG, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T, Rattei T, Arrowsmith S, Wray S, Marek A, Elbert T, Alewood PF, Gloriam DE, Gruber CW. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. 7: 41002. PMID 28145450 DOI: 10.1038/Srep41002  0.341
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, ... ... Alewood PF, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/Srep40883  0.367
2017 Abraham N, Healy M, Ragnarsson L, Brust A, Alewood PF, Lewis RJ. Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor. Scientific Reports. 7: 45466-45466. DOI: 10.2210/Pdb5T90/Pdb  0.319
2017 Alewood PF, Wade JD. Australasian Peptide Chemistry Australian Journal of Chemistry. 70: 125. DOI: 10.1071/Chv70N2_Fo  0.4
2017 Wan J, Mobli M, Brust A, Muttenthaler M, Andersson Å, Ragnarsson L, Castro J, Vetter I, Huang JX, Nilsson M, Brierley SM, Cooper MA, Lewis RJ, Alewood PF. Synthesis of Multivalent [Lys8]-Oxytocin Dendrimers that Inhibit Visceral Nociceptive Responses Australian Journal of Chemistry. 70: 162. DOI: 10.1071/Ch16407  0.407
2016 Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon : Official Journal of the International Society On Toxinology. PMID 27793656 DOI: 10.1016/J.Toxicon.2016.10.013  0.424
2016 Yang DC, Deuis JR, Dashevsky D, Dobson J, Jackson TN, Brust A, Xie B, Koludarov I, Debono J, Hendrikx I, Hodgson WC, Josh P, Nouwens A, Baillie GJ, Bruxner TJ, ... Alewood PF, et al. The Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus). Toxins. 8. PMID 27763551 DOI: 10.3390/Toxins8100303  0.405
2016 Touchard A, Brust A, Cardoso FC, Chin YK, Herzig V, Jin AH, Dejean A, Alewood PF, King GF, Orivel J, Escoubas P. Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica Et Biophysica Acta. PMID 27474999 DOI: 10.1016/J.Bbagen.2016.07.027  0.423
2016 Deuis JR, Dekan Z, Inserra MC, Lee TH, Aguilar MI, Craik DJ, Lewis RJ, Alewood PF, Mobli M, Schroeder CI, Henriques ST, Vetter I. Development of a μO-conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Target NaV1.8. The Journal of Biological Chemistry. PMID 27026701 DOI: 10.1074/Jbc.M116.721662  0.322
2016 Wan J, Alewood PF. Peptide-Decorated Dendrimers and Their Bioapplications. Angewandte Chemie (International Ed. in English). PMID 26990715 DOI: 10.1002/Anie.201508428  0.41
2016 Wan J, Brust A, Bhola RF, Jha P, Mobli M, Lewis RJ, Christie MJ, Alewood PF. Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 26910400 DOI: 10.1002/Psc.2857  0.403
2016 Brust A, Croker DE, Colless B, Ragnarsson L, Andersson A, Jain K, Caraballo SG, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-derived κ-opioid agonists (conorphins): potent, selective and metabolic stable dynorphinA mimetics with anti-nociceptive properties. Journal of Medicinal Chemistry. PMID 26859603 DOI: 10.1021/Acs.Jmedchem.5B00911  0.324
2016 Wan J, Alewood PF. Mit Peptiden dekorierte Dendrimere und ihre biotechnologische Nutzung Angewandte Chemie. 128: 5208-5219. DOI: 10.1002/Ange.201508428  0.353
2015 Reeks T, Lavergne V, Sunagar K, Jones A, Undheim E, Dunstan N, Fry B, Alewood PF. Deep venomics of the Pseudonaja genus reveals inter- and intra-specific variation. Journal of Proteomics. PMID 26632978 DOI: 10.1016/J.Jprot.2015.11.019  0.389
2015 Prashanth JR, Dutertre S, Jin AH, Lavergne V, Hamilton B, Cardoso FC, Griffin J, Venter DJ, Alewood PF, Lewis RJ. The role of defensive ecological interactions in the evolution of conotoxins. Molecular Ecology. PMID 26614983 DOI: 10.1111/Mec.13504  0.361
2015 Jin AH, Vetter I, Himaya SW, Alewood PF, Lewis RJ, Dutertre S. Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom. Proteomics. PMID 26506909 DOI: 10.1002/Pmic.201500220  0.341
2015 Himaya SW, Jin AH, Dutertre S, Giacomotto J, Mohialdeen H, Vetter I, Alewood PF, Lewis RJ. Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research. 14: 4372-81. PMID 26322961 DOI: 10.1021/Acs.Jproteome.5B00630  0.42
2015 Deuis JR, Whately E, Brust A, Inserra MC, Asvadi NH, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. Acs Chemical Neuroscience. 6: 1751-8. PMID 26225903 DOI: 10.1021/Acschemneuro.5B00113  0.329
2015 Jin AH, Israel MR, Inserra MC, Smith JJ, Lewis RJ, Alewood PF, Vetter I, Dutertre S. δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings. Biological Sciences / the Royal Society. 282. PMID 26156767 DOI: 10.1098/Rspb.2015.0817  0.371
2015 Lavergne V, Harliwong I, Jones A, Miller D, Taft RJ, Alewood PF. Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks. Proceedings of the National Academy of Sciences of the United States of America. 112: E3782-91. PMID 26150494 DOI: 10.1073/Pnas.1501334112  0.441
2015 Jouiaei M, Yanagihara AA, Madio B, Nevalainen TJ, Alewood PF, Fry BG. Ancient Venom Systems: A Review on Cnidaria Toxins. Toxins. 7: 2251-71. PMID 26094698 DOI: 10.3390/Toxins7062251  0.314
2015 Cardoso FC, Dekan Z, Rosengren KJ, Erickson A, Vetter I, Deuis JR, Herzig V, Alewood PF, King GF, Lewis RJ. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Molecular Pharmacology. 88: 291-303. PMID 25979003 DOI: 10.1124/Mol.115.098178  0.412
2015 Ziegman R, Alewood P. Bioactive components in fish venoms. Toxins. 7: 1497-531. PMID 25941767 DOI: 10.3390/Toxins7051497  0.377
2015 Jouiaei M, Sunagar K, Federman Gross A, Scheib H, Alewood PF, Moran Y, Fry BG. Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemone. Molecular Biology and Evolution. 32: 1598-610. PMID 25757852 DOI: 10.1093/Molbev/Msv050  0.378
2015 Reeks T, Jones A, Brust A, Sridharan S, Corcilius L, Wilkinson BL, Thaysen-Andersen M, Payne RJ, Kini RM, Daly NL, Alewood PF. A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie (International Ed. in English). 54: 4828-31. PMID 25735823 DOI: 10.1002/Anie.201411914  0.418
2015 Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/Jacs.5B00244  0.465
2015 Reeks TA, Fry BG, Alewood PF. Privileged frameworks from snake venom Cellular and Molecular Life Sciences. 72: 1939-1958. PMID 25693678 DOI: 10.1007/S00018-015-1844-Z  0.399
2015 Mueller A, Starobova H, Inserra MC, Jin AH, Deuis JR, Dutertre S, Lewis RJ, Alewood PF, Daly NL, Vetter I. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology. 94: 155-63. PMID 25646788 DOI: 10.1016/J.Bcp.2015.01.011  0.338
2015 Gori A, Wang CI, Harvey PJ, Rosengren KJ, Bhola RF, Gelmi ML, Longhi R, Christie MJ, Lewis RJ, Alewood PF, Brust A. Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic. Angewandte Chemie (International Ed. in English). 54: 1361-4. PMID 25483297 DOI: 10.1002/Anie.201409678  0.336
2014 Prashanth JR, Brust A, Jin AH, Alewood PF, Dutertre S, Lewis RJ. Cone snail venomics: from novel biology to novel therapeutics. Future Medicinal Chemistry. 6: 1659-75. PMID 25406006 DOI: 10.4155/Fmc.14.99  0.345
2014 Jensen JE, Cristofori-Armstrong B, Anangi R, Rosengren KJ, Lau CH, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores. Journal of Medicinal Chemistry. 57: 9195-203. PMID 25337890 DOI: 10.1021/Jm501400P  0.409
2014 Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42. PMID 25101833 DOI: 10.1016/J.Bcp.2014.07.025  0.477
2014 Wang CI, Reeks T, Vetter I, Vergara I, Kovtun O, Lewis RJ, Alewood PF, Durek T. Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry. 53: 3758-66. PMID 24867092 DOI: 10.1021/Bi5004475  0.379
2014 Akondi KB, Muttenthaler M, Dutertre S, Kaas Q, Craik DJ, Lewis RJ, Alewood PF. Discovery, synthesis, and structure-activity relationships of conotoxins. Chemical Reviews. 114: 5815-47. PMID 24720541 DOI: 10.1021/Cr400401E  0.347
2014 Dutertre S, Jin AH, Vetter I, Hamilton B, Sunagar K, Lavergne V, Dutertre V, Fry BG, Antunes A, Venter DJ, Alewood PF, Lewis RJ. Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications. 5: 3521. PMID 24662800 DOI: 10.1038/Ncomms4521  0.315
2014 Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology. 171: 3313-27. PMID 24628243 DOI: 10.1111/Bph.12686  0.422
2014 Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie (International Ed. in English). 53: 2931-4. PMID 24604812 DOI: 10.1002/Anie.201310103  0.358
2014 Brust A, Schroeder CI, Alewood PF. High-throughput synthesis of peptide α-thioesters: a safety catch linker approach enabling parallel hydrogen fluoride cleavage. Chemmedchem. 9: 1038-46. PMID 24591329 DOI: 10.1002/Cmdc.201300524  0.432
2014 Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochemical Pharmacology. 89: 276-86. PMID 24561180 DOI: 10.1016/J.Bcp.2014.02.008  0.524
2014 Gui J, Liu B, Cao G, Lipchik AM, Perez M, Dekan Z, Mobli M, Daly NL, Alewood PF, Parker LL, King GF, Zhou Y, Jordt SE, Nitabach MN. A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology : Cb. 24: 473-83. PMID 24530065 DOI: 10.1016/J.Cub.2014.01.013  0.403
2014 de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications. 5: 3165. PMID 24476666 DOI: 10.1038/Ncomms4165  0.406
2014 Jin AH, Vetter I, Dutertre S, Abraham N, Emidio NB, Inserra M, Murali SS, Christie MJ, Alewood PF, Lewis RJ. MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors. Biochemistry. 53: 1-3. PMID 24351107 DOI: 10.1021/Bi400882S  0.355
2014 Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie (International Ed. in English). 53: 1017-20. PMID 24323786 DOI: 10.1002/Anie.201308898  0.445
2014 Akondi KB, Lewis RJ, Alewood PF. Re-engineering the μ-conotoxin SIIIA scaffold. Biopolymers. 101: 347-54. PMID 23913763 DOI: 10.1002/Bip.22368  0.343
2014 Gori A, Wang CA, Harvey PJ, Rosengren KJ, Bhola RF, Gelmi ML, Longhi R, Christie MJ, Lewis RJ, Alewood PF, Brust A. Stabilisierung eines cysteinreichen Kegelschneckentoxins, MrIA, in Form eines 1,2,3-Triazol-Disulfidbrückenmimetikums Angewandte Chemie. 127: 1378-1381. DOI: 10.1002/Ange.201409678  0.322
2013 Lavergne V, Dutertre S, Jin AH, Lewis RJ, Taft RJ, Alewood PF. Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. Bmc Genomics. 14: 708. PMID 24131469 DOI: 10.1186/1471-2164-14-708  0.31
2013 Brust A, Wang CI, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Ed. in English). 52: 12020-3. PMID 24115503 DOI: 10.1002/Anie.201304660  0.421
2013 Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/Jbc.M113.512582  0.509
2013 Jin AH, Dutertre S, Kaas Q, Lavergne V, Kubala P, Lewis RJ, Alewood PF. Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Molecular & Cellular Proteomics : McP. 12: 3824-33. PMID 24043424 DOI: 10.1074/Mcp.M113.030353  0.421
2013 Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/J.Bcp.2013.07.016  0.509
2013 Ruder T, Ali SA, Ormerod K, Brust A, Roymanchadi ML, Ventura S, Undheim EA, Jackson TN, Mercier AJ, King GF, Alewood PF, Fry BG. Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides. 47: 71-6. PMID 23850991 DOI: 10.1016/J.Peptides.2013.07.002  0.429
2013 Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. Quantification of lactosylation of whey proteins in stored milk powder using multiple reaction monitoring. Food Chemistry. 141: 1203-10. PMID 23790905 DOI: 10.1016/J.Foodchem.2013.03.073  0.328
2013 Smith JJ, Vetter I, Lewis RJ, Peigneur S, Tytgat J, Lam A, Gallant EM, Beard NA, Alewood PF, Dulhunty AF. Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins. Proceedings of the National Academy of Sciences of the United States of America. 110: 8906-11. PMID 23671114 DOI: 10.1073/Pnas.1214062110  0.367
2013 Ghassemian A, Vila-Farrés X, Alewood PF, Durek T. Solid phase synthesis of peptide-selenoesters. Bioorganic & Medicinal Chemistry. 21: 3473-8. PMID 23608106 DOI: 10.1016/J.Bmc.2013.03.076  0.427
2013 Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. Acs Chemical Biology. 8: 1215-22. PMID 23527544 DOI: 10.1021/Cb400012K  0.517
2013 Smith JJ, Herzig V, King GF, Alewood PF. The insecticidal potential of venom peptides. Cellular and Molecular Life Sciences : Cmls. 70: 3665-93. PMID 23525661 DOI: 10.1007/S00018-013-1315-3  0.419
2013 Ghassemian A, Wang CI, Yau MK, Reid RC, Lewis RJ, Fairlie DP, Alewood PF, Durek T. Efficient chemical synthesis of human complement protein C3a. Chemical Communications (Cambridge, England). 49: 2356-8. PMID 23407800 DOI: 10.1039/C3Cc40537K  0.308
2013 Brust A, Sunagar K, Undheim EA, Vetter I, Yang DC, Yang DC, Casewell NR, Jackson TN, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, et al. Differential evolution and neofunctionalization of snake venom metalloprotease domains. Molecular & Cellular Proteomics : McP. 12: 651-63. PMID 23242553 DOI: 10.1074/Mcp.M112.023135  0.383
2013 Dutertre S, Jin AH, Kaas Q, Jones A, Alewood PF, Lewis RJ. Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Molecular & Cellular Proteomics : McP. 12: 312-29. PMID 23152539 DOI: 10.1074/Mcp.M112.021469  0.398
2013 Vink S, Alewood PF. Targeting voltage-gated calcium channels: developments in peptide and small-molecule inhibitors for the treatment of neuropathic pain. British Journal of Pharmacology. 167: 970-89. PMID 22725651 DOI: 10.1111/J.1476-5381.2012.02082.X  0.351
2012 Schroeder CI, Nielsen KJ, Adams DA, Loughnan M, Thomas L, Alewood PF, Lewis RJ, Craik DJ. Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers. 98: 345-56. PMID 23193599 DOI: 10.1002/Bip.22031  0.372
2012 de Araujo AD, Mobli M, King GF, Alewood PF. Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie (International Ed. in English). 51: 10298-302. PMID 22991244 DOI: 10.1002/Anie.201204229  0.413
2012 Jensen JE, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3. Marine Drugs. 10: 1511-27. PMID 22851922 DOI: 10.3390/Md10071511  0.438
2012 Lavergne V, Taft RJ, Alewood PF. Cysteine-rich mini-proteins in human biology. Current Topics in Medicinal Chemistry. 12: 1514-33. PMID 22827521 DOI: 10.2174/156802612802652411  0.353
2012 Schroeder CI, Adams D, Thomas L, Alewood PF, Lewis RJ. N- and C-terminal extensions of μ-conotoxins increase potency and selectivity for neuronal sodium channels. Biopolymers. 98: 161-5. PMID 22733528 DOI: 10.1002/Bip.22032  0.406
2012 Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochemical Pharmacology. 84: 540-8. PMID 22609441 DOI: 10.1016/J.Bcp.2012.05.008  0.481
2012 Dekan Z, Wang CI, Andrews RK, Lewis RJ, Alewood PF. Conotoxin engineering: dual pharmacophoric noradrenaline transport inhibitor/integrin binding peptide with improved stability. Organic & Biomolecular Chemistry. 10: 5791-4. PMID 22581211 DOI: 10.1039/C2Ob25133G  0.403
2012 Beaumont KA, Smit DJ, Liu YY, Chai E, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Sturm RA. Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. Pigment Cell & Melanoma Research. 25: 370-4. PMID 22364200 DOI: 10.1111/J.1755-148X.2012.00990.X  0.323
2012 Napier IA, Klimis H, Rycroft BK, Jin AH, Alewood PF, Motin L, Adams DJ, Christie MJ. Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain. Neuropharmacology. 62: 2202-7. PMID 22306793 DOI: 10.1016/J.Neuropharm.2012.01.016  0.467
2012 Hjørringgaard CU, Brust A, Alewood PF. Evaluation of COMU as a coupling reagent for in situ neutralization Boc solid phase peptide synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 199-207. PMID 22252935 DOI: 10.1002/Psc.1438  0.348
2012 Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marí F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/J.Bcp.2011.11.006  0.507
2012 Franco A, Heighinian M, Mejia M, McCall J, Nag S, Akondi K, Melaun C, Daly N, Luetje CW, Alewood PF, Craik DJ, Godenschwege T, Adams DJ, Marí F. 105. Discovery, Characterization, and Functional Implications of Conotoxins from Cone Snails Species of the Americas Toxicon. 60: 148. DOI: 10.1016/J.Toxicon.2012.04.106  0.383
2012 Dutertre S, Jin A, Alewood PF, Lewis RJ. 99. The Venom of Conus geographus Revisited Toxicon. 60: 145. DOI: 10.1016/J.Toxicon.2012.04.100  0.343
2011 Muttenthaler M, Akondi KB, Alewood PF. Structure-activity studies on alpha-conotoxins. Current Pharmaceutical Design. 17: 4226-41. PMID 22204424 DOI: 10.2174/138161211798999384  0.47
2011 de Araujo AD, Christensen C, Buchardt J, Kent SB, Alewood PF. Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 13983-6. PMID 22084036 DOI: 10.1002/Chem.201102732  0.326
2011 Durek T, Alewood PF. Preformed selenoesters enable rapid native chemical ligation at intractable sites. Angewandte Chemie (International Ed. in English). 50: 12042-5. PMID 21997950 DOI: 10.1002/Anie.201105512  0.412
2011 Dekan Z, Vetter I, Daly NL, Craik DJ, Lewis RJ, Alewood PF. α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society. 133: 15866-9. PMID 21899353 DOI: 10.1021/Ja206408Q  0.411
2011 Smith JJ, Hill JM, Little MJ, Nicholson GM, King GF, Alewood PF. Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif. Proceedings of the National Academy of Sciences of the United States of America. 108: 10478-83. PMID 21670253 DOI: 10.1073/Pnas.1103501108  0.444
2011 de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/Anie.201101642  0.502
2011 Wijffels G, Johnson WM, Oakley AJ, Turner K, Epa VC, Briscoe SJ, Polley M, Liepa AJ, Hofmann A, Buchardt J, Christensen C, Prosselkov P, Dalrymple BP, Alewood PF, Jennings PA, et al. Binding inhibitors of the bacterial sliding clamp by design. Journal of Medicinal Chemistry. 54: 4831-8. PMID 21604761 DOI: 10.1021/Jm2004333  0.327
2011 Rash LD, Morales RA, Vink S, Alewood PF. De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina). Toxicon : Official Journal of the International Society On Toxinology. 57: 208-16. PMID 21115026 DOI: 10.1016/J.Toxicon.2010.11.012  0.418
2011 Klimis H, Adams DJ, Callaghan B, Nevin S, Alewood PF, Vaughan CW, Mozar CA, Christie MJ. A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152: 259-66. PMID 20889259 DOI: 10.1016/J.Pain.2010.09.007  0.454
2011 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis J, Alewood PF, Christie MJ, Adams DJ. Analgesic ω-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels (Molecular Pharmacology (2010) 77, (139-148)) Molecular Pharmacology. 80: 356. DOI: 10.1124/Mol.80.2.356  0.428
2011 Adams D, Grishin A, Hung A, Clark R, Akondi K, Alewood P, Craik D. Scanning mutagenesis of α-conotoxin AuIB reveals a critical residue for activity at the α3β4 nicotinic acetylcholine receptor Biochemical Pharmacology. 82: 1028. DOI: 10.1016/J.Bcp.2011.07.017  0.444
2010 Vink S, Jin AH, Poth KJ, Head GA, Alewood PF. Natriuretic peptide drug leads from snake venom. Toxicon : Official Journal of the International Society On Toxinology. 59: 434-45. PMID 21147145 DOI: 10.1016/J.Toxicon.2010.12.001  0.406
2010 Alewood D, Hopping G, Brust A, Reid RC, Alewood PF. Benzhydrylamine linker grafting: a strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 551-7. PMID 20862722 DOI: 10.1002/Psc.1248  0.399
2010 Morales RA, Daly NL, Vetter I, Mobli M, Napier IA, Craik DJ, Lewis RJ, Christie MJ, King GF, Alewood PF, Durek T. Chemical synthesis and structure of the prokineticin Bv8. Chembiochem : a European Journal of Chemical Biology. 11: 1882-8. PMID 20677202 DOI: 10.1002/Cbic.201000330  0.408
2010 Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 285: 22254-63. PMID 20466726 DOI: 10.1074/Jbc.M110.111880  0.471
2010 Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22. PMID 20163143 DOI: 10.1021/Ja910602H  0.485
2010 Luo S, Akondi KB, Zhangsun D, Wu Y, Zhu X, Hu Y, Christensen S, Dowell C, Daly NL, Craik DJ, Wang CIA, Lewis RJ, Alewood PF, McIntosh JM. Atypical α-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor Journal of Biological Chemistry. 285: 12355-12366. PMID 20145249 DOI: 10.1074/Jbc.M109.079012  0.362
2010 Armishaw CJ, Dutton JL, Craik DJ, Alewood PF. Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogs. Biopolymers. 94: 307-13. PMID 20013812 DOI: 10.1002/Bip.21360  0.378
2010 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ. Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels. Molecular Pharmacology. 77: 139-48. PMID 19892914 DOI: 10.1124/Mol.109.058834  0.484
2009 Brust A, Palant E, Croker DE, Colless B, Drinkwater R, Patterson B, Schroeder CI, Wilson D, Nielsen CK, Smith MT, Alewood D, Alewood PF, Lewis RJ. chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry. 52: 6991-7002. PMID 19860431 DOI: 10.1021/Jm9003413  0.346
2009 Vernall AJ, Cassidy P, Alewood PF. A single alpha-helical turn stabilized by replacement of an internal hydrogen bond with a covalent ethylene bridge. Angewandte Chemie (International Ed. in English). 48: 5675-8. PMID 19562809 DOI: 10.1002/Anie.200901059  0.31
2009 Ueberheide BM, Fenyö D, Alewood PF, Chait BT. Rapid sensitive analysis of cysteine rich peptide venom components. Proceedings of the National Academy of Sciences of the United States of America. 106: 6910-5. PMID 19380747 DOI: 10.1073/Pnas.0900745106  0.441
2009 Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon. 54: 56-61. PMID 19306891 DOI: 10.1016/J.Toxicon.2009.03.014  0.514
2009 Pages G, Torres AM, Ju P, Bansal PS, Alewood PF, Kuchel PW, Vandenberg JI. Structure of the pore-helix of the hERG K(+) channel. European Biophysics Journal : Ebj. 39: 111-20. PMID 19305991 DOI: 10.1007/S00249-009-0433-1  0.424
2009 Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/Jbc.M804950200  0.507
2009 Hopping G, Lewis RJ, Alewood PF. Rapid access to ω-conotoxin chimeras using native chemical ligation Australian Journal of Chemistry. 62: 1333-1338. DOI: 10.1071/Ch09216  0.424
2008 Muttenthaler M, Alewood PF. Selenopeptide chemistry. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 1223-39. PMID 18951416 DOI: 10.1002/psc.1075  0.312
2008 Poth AG, Deeth HC, Alewood PF, Holland JW. Analysis of the human casein phosphoproteome by 2-D electrophoresis and MALDI-TOF/TOF MS reveals new phosphoforms Journal of Proteome Research. 7: 5017-5027. PMID 18847231 DOI: 10.1021/Pr800387S  0.305
2008 Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84. PMID 18754612 DOI: 10.1021/Jm800278K  0.465
2008 Holland JW, Deeth HC, Alewood PF. Analysis of disulphide linkages in bovine κ-casein oligomers using two-dimensional electrophoresis Electrophoresis. 29: 2402-2410. PMID 18548457 DOI: 10.1002/Elps.200700840  0.313
2008 Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. The Journal of Biological Chemistry. 283: 21621-8. PMID 18522941 DOI: 10.1074/Jbc.M802852200  0.497
2008 Imperial JS, Chen P, Sporning A, Terlau H, Daly NL, Craik DJ, Alewood PF, Olivera BM. Tyrosine-rich conopeptides affect voltage-gated K+ channels. The Journal of Biological Chemistry. 283: 23026-32. PMID 18505731 DOI: 10.1074/Jbc.M800084200  0.447
2008 Tyndall JD, Pattenden LK, Reid RC, Hu SH, Alewood D, Alewood PF, Walsh T, Fairlie DP, Martin JL. Crystal structures of highly constrained substrate and hydrolysis products bound to HIV-1 protease. Implications for the catalytic mechanism. Biochemistry. 47: 3736-44. PMID 18311928 DOI: 10.1021/Bi7023157  0.341
2008 Yan WX, Armishaw C, Goyette J, Yang Z, Cai H, Alewood P, Geczy CL. Mast cell and monocyte recruitment by S100A12 and its hinge domain. The Journal of Biological Chemistry. 283: 13035-43. PMID 18292089 DOI: 10.1074/Jbc.M710388200  0.321
2008 Dutertre S, Croker D, Daly NL, Andersson A, Muttenthaler M, Lumsden NG, Craik DJ, Alewood PF, Guillon G, Lewis RJ. Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. The Journal of Biological Chemistry. 283: 7100-8. PMID 18174156 DOI: 10.1074/Jbc.M706477200  0.36
2007 Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, Hopping G, Alewood PF, Schroeder C, Nicke A, Smit AB, Sixma TK, Lewis RJ. AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. The Embo Journal. 26: 3858-67. PMID 17660751 DOI: 10.1038/Sj.Emboj.7601785  0.362
2007 Blanchfield JT, Gallagher OP, Cros C, Lewis RJ, Alewood PF, Toth I. Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochemical and Biophysical Research Communications. 361: 97-102. PMID 17640618 DOI: 10.1016/J.Bbrc.2007.06.138  0.408
2007 Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28  0.457
2007 Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Molecular Pharmacology. 71: 676-85. PMID 17142296 DOI: 10.1124/Mol.106.028225  0.527
2007 Nair DG, Fry BG, Alewood P, Kumar PP, Kini RM. Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins. The Biochemical Journal. 402: 93-104. PMID 17044815 DOI: 10.1042/Bj20060318  0.331
2007 Torres AM, Tsampazi M, Kennett EC, Belov K, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. Characterization and isolation of L-to-D-amino-acid-residue isomerase from platypus venom. Amino Acids. 32: 63-8. PMID 16729187 DOI: 10.1007/S00726-006-0346-6  0.395
2007 Dekan Z, Paczkowski FA, Lewis RJ, Alewood PF. Synthesis and In vitro Biological Activity of Cyclic Lipophilic χ-Conotoxin MrIA Analogues International Journal of Peptide Research and Therapeutics. 13: 307-312. DOI: 10.1007/S10989-007-9083-2  0.44
2007 Schnölzer M, Alewood P, Jones A, Alewood D, Kent SBH. In situ neutralization in boc-chemistry solid phase peptide synthesis: Rapid, high yield assembly of difficult sequences International Journal of Peptide Research and Therapeutics. 13: 31-44. DOI: 10.1007/S10989-006-9059-7  0.346
2006 Lovelace ES, Armishaw CJ, Colgrave ML, Wahlstrom ME, Alewood PF, Daly NL, Craik DJ. Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. Journal of Medicinal Chemistry. 49: 6561-8. PMID 17064074 DOI: 10.1021/Jm060299H  0.454
2006 St Pierre L, Flight S, Masci PP, Hanchard KJ, Lewis RJ, Alewood PF, de Jersey J, Lavin MF. Cloning and characterisation of natriuretic peptides from the venom glands of Australian elapids. Biochimie. 88: 1923-31. PMID 16908092 DOI: 10.1016/J.Biochi.2006.06.014  0.44
2006 Imperial JS, Bansal PS, Alewood PF, Daly NL, Craik DJ, Sporning A, Terlau H, López-Vera E, Bandyopadhyay PK, Olivera BM. A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry. 45: 8331-40. PMID 16819832 DOI: 10.1021/Bi060263R  0.449
2006 Dutertre S, Lumsden NG, Alewood PF, Lewis RJ. Isolation and characterisation of conomap-Vt, a D-amino acid containing excitatory peptide from the venom of a vermivorous cone snail. Febs Letters. 580: 3860-6. PMID 16797543 DOI: 10.1016/J.Febslet.2006.06.011  0.407
2006 Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/Jbc.M603703200  0.566
2006 Holland JW, Deeth HC, Alewood PF. Resolution and characterisation of multiple isoforms of bovine κ-casein by 2-DE following a reversible cysteine-tagging enrichment strategy Proteomics. 6: 3087-3095. PMID 16619295 DOI: 10.1002/Pmic.200500780  0.326
2006 Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists Journal of Biological Chemistry. 281: 14136-14143. PMID 16500898 DOI: 10.1074/Jbc.M512419200  0.527
2006 Torres AM, Tsampazi M, Tsampazi C, Kennett EC, Belov K, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. Mammalian l-to-d-amino-acid-residue isomerase from platypus venom. Febs Letters. 580: 1587-91. PMID 16480722 DOI: 10.1016/J.Febslet.2006.01.089  0.346
2006 Brust A, Alewood D, Colless B, Palant E, Patterson B, Wilson DTR, Watson F, Schroeder CI, Alewood PF, Lewis RJ. conopeptide to drug: the development, structure and activity correlation of Xen2174 Journal of Peptide Science. 12: 516-516. DOI: 10.1002/Psc.797  0.41
2005 Bansal PS, Grieve PA, Marschke RJ, Daly NL, McGhie E, Craik DJ, Alewood PF. Chemical synthesis and structure elucidation of bovine kappa-casein (1-44). Biochemical and Biophysical Research Communications. 340: 1098-103. PMID 16403439 DOI: 10.1016/J.Bbrc.2005.12.115  0.361
2005 Torres AM, Tsampazi C, Geraghty DP, Bansal PS, Alewood PF, Kuchel PW. D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties. The Biochemical Journal. 391: 215-20. PMID 16033333 DOI: 10.1042/Bj20050900  0.371
2005 Alewood D, Nielsen K, Alewood PF, Craik DJ, Andrews P, Nerrie M, White S, Domagala T, Walker F, Rothacker J, Burgess AW, Nice EC. The role of disulfide bonds in the structure and function of murine epidermal growth factor (mEGF). Growth Factors (Chur, Switzerland). 23: 97-110. PMID 16019431 DOI: 10.1080/08977190500096061  0.388
2005 Wen S, Wilson DT, Kuruppu S, Korsinczky ML, Hedrick J, Pang L, Szeto T, Hodgson WC, Alewood PF, Nicholson GM. Discovery of an MIT-like atracotoxin family: spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins. Peptides. 26: 2412-26. PMID 15979762 DOI: 10.1016/J.Peptides.2005.05.012  0.417
2005 Armishaw CJ, Alewood PF. Conotoxins as research tools and drug leads. Current Protein & Peptide Science. 6: 221-40. PMID 15974949 DOI: 10.2174/1389203054065437  0.416
2005 Nilsson KP, Lovelace ES, Caesar CE, TynngÃ¥rd N, Alewood PF, Johansson HM, Sharpe IA, Lewis RJ, Daly NL, Craik DJ. Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter. Biopolymers. 80: 815-23. PMID 15931669 DOI: 10.1002/Bip.20302  0.374
2005 Baudinette RV, Boontheung P, Musgrave IF, Wabnitz PA, Maselli VM, Skinner J, Alewood PF, Brinkworth CS, Bowie JH. An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii. The Febs Journal. 272: 433-43. PMID 15654881 DOI: 10.1111/J.1742-4658.2004.04483.X  0.407
2005 Fry BG, Wickramaratana JC, Lemme S, Beuve A, Garbers D, Hodgson WC, Alewood P. Novel natriuretic peptides from the venom of the inland taipan (Oxyuranus microlepidotus): isolation, chemical and biological characterisation. Biochemical and Biophysical Research Communications. 327: 1011-5. PMID 15652496 DOI: 10.1016/J.Bbrc.2004.11.171  0.386
2004 Wickramaratna JC, Fry BG, Loiacono RE, Aguilar MI, Alewood PF, Hodgson WC. Isolation and characterization at cholinergic nicotinic receptors of a neurotoxin from the venom of the Acanthophis sp. Seram death adder. Biochemical Pharmacology. 68: 383-94. PMID 15194010 DOI: 10.1016/J.Bcp.2004.03.033  0.34
2004 Loughnan ML, Alewood PF. Physico-chemical characterization and synthesis of neuronally active alpha-conotoxins. European Journal of Biochemistry. 271: 2294-304. PMID 15182345 DOI: 10.1111/J.1432-1033.2004.04146.X  0.396
2004 Wijffels G, Dalrymple BP, Prosselkov P, Kongsuwan K, Epa VC, Lilley PE, Jergic S, Buchardt J, Brown SE, Alewood PF, Jennings PA, Dixon NE. Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins. Biochemistry. 43: 5661-71. PMID 15134440 DOI: 10.1021/Bi036229J  0.319
2004 Holland JW, Deeth HC, Alewood PF. Proteomic analysis of κ-casein micro-heterogeneity Proteomics. 4: 743-752. PMID 14997496 DOI: 10.1002/Pmic.200300613  0.327
2004 Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/Jm031010O  0.518
2004 Wilson D, Alewood P. Australian funnel-web spider venom analyzed with on-line RP-HPLC techniques. Methods in Molecular Biology (Clifton, N.J.). 251: 307-22. PMID 14704454 DOI: 10.1385/1-59259-742-4:307  0.311
2004 Alewood D, Birinyi-Strachan LC, Pallaghy PK, Norton RS, Nicholson GM, Alewood PF. Synthesis and characterization of delta-atracotoxin-Ar1a, the lethal neurotoxin from venom of the Sydney funnel-web spider (Atrax robustus). Biochemistry. 42: 12933-40. PMID 14596608 DOI: 10.1021/Bi030091N  0.409
2003 Torres AM, Bansal PS, Sunde M, Clarke CE, Bursill JA, Smith DJ, Bauskin A, Breit SN, Campbell TJ, Alewood PF, Kuchel PW, Vandenberg JI. Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation. The Journal of Biological Chemistry. 278: 42136-48. PMID 12902341 DOI: 10.1074/Jbc.M212824200  0.387
2003 Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. The Journal of Biological Chemistry. 278: 40317-23. PMID 12885787 DOI: 10.1074/Jbc.M213030200  0.495
2003 Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of Biological Chemistry. 278: 34451-7. PMID 12824165 DOI: 10.1074/Jbc.M305410200  0.498
2003 Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/Jbc.M212628200  0.449
2003 Torres AM, Bansal P, Alewood PF, Bursill JA, Kuchel PW, Vandenberg JI. Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin. Febs Letters. 539: 138-42. PMID 12650941 DOI: 10.1016/S0014-5793(03)00216-3  0.351
2003 Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. Journal of Medicinal Chemistry. 46: 1266-72. PMID 12646037 DOI: 10.1021/Jm020426J  0.579
2003 Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/Jbc.M210280200  0.444
2003 Englebretsen DR, Garnham B, Alewood PF. A cassette ligation strategy with thioether replacement of three Gly-Gly peptide bonds: total chemical synthesis of the 101 residue protein early pregnancy factor [psi(CH(2)S)28-29,56-57,76-77]. The Journal of Organic Chemistry. 67: 5883-90. PMID 12182617 DOI: 10.1021/Jo016121E  0.431
2003 Alewood P, Hopping G, Armishaw C. Marine Toxins as Sources of Drug Leads Australian Journal of Chemistry. 56: 769. DOI: 10.1071/Ch03043  0.377
2002 Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. The Journal of Biological Chemistry. 277: 48849-57. PMID 12376538 DOI: 10.1074/Jbc.M208842200  0.556
2002 Torres AM, Alewood D, Alewood PF, Gallagher CH, Kuchel PW. Conformations of platypus venom C-type natriuretic peptide in aqueous solution and sodium dodecyl sulfate micelles. Toxicon : Official Journal of the International Society On Toxinology. 40: 711-9. PMID 12175607 DOI: 10.1016/S0041-0101(01)00266-5  0.359
2002 Torres AM, Menz I, Alewood PF, Bansal P, Lahnstein J, Gallagher CH, Kuchel PW. D-Amino acid residue in the C-type natriuretic peptide from the venom of the mammal, Ornithorhynchus anatinus, the Australian platypus. Febs Letters. 524: 172-6. PMID 12135762 DOI: 10.1016/S0014-5793(02)03050-8  0.373
2002 Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. The Journal of Biological Chemistry. 277: 27247-55. PMID 12006587 DOI: 10.1074/Jbc.M201611200  0.501
2002 Rosengren KJ, Wilson D, Daly NL, Alewood PF, Craik DJ. Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry. 41: 3294-301. PMID 11876637 DOI: 10.1021/Bi011932Y  0.379
2002 Boontheung P, Alewood PF, Brinkworth CS, Bowie JH, Wabnitz PA, Tyler MJ. Negative ion electrospray mass spectra of caerulein peptides: an aid to structural determination. Rapid Communications in Mass Spectrometry : Rcm. 16: 281-6. PMID 11816042 DOI: 10.1002/Rcm.577  0.349
2001 Bourne GT, Golding SW, McGeary RP, Meutermans WD, Jones A, Marshall GR, Alewood PF, Smythe ML. The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides. The Journal of Organic Chemistry. 66: 7706-13. PMID 11701025 DOI: 10.1021/Jo010580Y  0.431
2001 Sharpe IA, Gehrmann J, Loughnan ML, Thomas L, Adams DA, Atkins A, Palant E, Craik DJ, Adams DJ, Alewood PF, Lewis RJ. Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nature Neuroscience. 4: 902-7. PMID 11528421 DOI: 10.1038/Nn0901-902  0.523
2001 Wang XH, Connor M, Wilson D, Wilson HI, Nicholson GM, Smith R, Shaw D, Mackay JP, Alewood PF, Christie MJ, King GF. Discovery and structure of a potent and highly specific blocker of insect calcium channels. The Journal of Biological Chemistry. 276: 40306-12. PMID 11522785 DOI: 10.1074/Jbc.M105206200  0.326
2001 Wilce JA, Love SG, Richardson SJ, Alewood PF, Craik DJ. Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation. The Journal of Biological Chemistry. 276: 25997-6003. PMID 11352912 DOI: 10.1074/Jbc.M101228200  0.343
2001 Miranda LP, Tao T, Jones A, Chernushevich I, Standing KG, Geczy CL, Alewood PF. Total chemical synthesis and chemotactic activity of human S100A12 (EN-RAGE). Febs Letters. 488: 85-90. PMID 11163801 DOI: 10.1016/S0014-5793(00)02392-9  0.331
2001 Miranda LP, Alewood PF. Challenges for protein chemical synthesis in the 21st century: bridging genomics and proteomics. Biopolymers. 55: 217-26. PMID 11074416 DOI: 10.1002/1097-0282(2000)55:3<217::Aid-Bip40>3.0.Co;2-B  0.353
2001 Blanchfield J, Dutton J, Hogg R, Craik D, Adams D, Lewis R, Alewood P, Toth I. The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII Letters in Peptide Science. 8: 235-239. DOI: 10.1023/A:1016577832311  0.555
2001 Blanchfield J, Dutton J, Hogg R, Craik D, Adams D, Lewis R, Alewood P, Toth I. Letters in Peptide Science. 8: 235-239. DOI: 10.1023/A:1016577832311  0.315
2000 Miranda LP, Meutermans WD, Smythe ML, Alewood PF. An activated O --> N acyl transfer auxiliary: efficient amide-backbone substitution of hindered "difficult" peptides. The Journal of Organic Chemistry. 65: 5460-8. PMID 10970282 DOI: 10.1021/Jo991340+  0.408
2000 Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L, Jones A, Matheson JL, Drinkwater R, Andrews PR, Alewood PF. Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. The Journal of Biological Chemistry. 275: 35335-44. PMID 10938268 DOI: 10.1074/Jbc.M002252200  0.462
2000 Hill JM, Alewood PF, Craik DJ. Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 2. Three-dimensional solution structure. European Journal of Biochemistry / Febs. 267: 4649-57. PMID 10903497 DOI: 10.1046/J.1432-1327.2000.01507.X  0.402
2000 Hill JM, Atkins AR, Loughnan ML, Jones A, Adams DA, Martin RC, Lewis RJ, Craik DJ, Alewood PF. Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 1. Isolation, characterization and chemical synthesis. European Journal of Biochemistry / Febs. 267: 4642-8. PMID 10903496 DOI: 10.1046/J.1432-1327.2000.01508.X  0.453
2000 Broxton N, Miranda L, Gehrmann J, Down J, Alewood P, Livett B. Leu(10) of alpha-conotoxin PnIB confers potency for neuronal nicotinic responses in bovine chromaffin cells. European Journal of Pharmacology. 390: 229-36. PMID 10708728 DOI: 10.1016/S0014-2999(00)00023-6  0.386
1999 Bourne GT, Meutermans WD, Alewood PF, McGeary RP, Scanlon M, Watson AA, Smythe ML. A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1(,). The Journal of Organic Chemistry. 64: 3095-3101. PMID 11674407 DOI: 10.1021/Jo9818780  0.422
1999 Hogg RC, Miranda LP, Craik DJ, Lewis RJ, Alewood PF, Adams DJ. Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 274: 36559-64. PMID 10593955 DOI: 10.1074/Jbc.274.51.36559  0.473
1999 Daly NL, Love S, Alewood PF, Craik DJ. Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1. Biochemistry. 38: 10606-14. PMID 10441158 DOI: 10.1021/Bi990605B  0.419
1999 Gehrmann J, Daly NL, Alewood PF, Craik DJ. Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance. Journal of Medicinal Chemistry. 42: 2364-72. PMID 10395477 DOI: 10.1021/Jm990114P  0.389
1999 Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP. Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry. 38: 7978-88. PMID 10387041 DOI: 10.1021/Bi990174X  0.396
1999 Nielsen KJ, Adams D, Thomas L, Bond T, Alewood PF, Craik DJ, Lewis RJ. Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels. Journal of Molecular Biology. 289: 1405-21. PMID 10373375 DOI: 10.1006/Jmbi.1999.2817  0.532
1999 Nielsen KJ, Adams DA, Alewood PF, Lewis RJ, Thomas L, Schroeder T, Craik DJ. Effects of chirality at Tyr13 on the structure-activity relationships of omega-conotoxins from Conus magus. Biochemistry. 38: 6741-51. PMID 10346894 DOI: 10.1021/Bi982980U  0.366
1999 Broxton NM, Down JG, Gehrmann J, Alewood PF, Satchell DG, Livett BG. Alpha-conotoxin ImI inhibits the alpha-bungarotoxin-resistant nicotinic response in bovine adrenal chromaffin cells. Journal of Neurochemistry. 72: 1656-62. PMID 10098874 DOI: 10.1046/J.1471-4159.1999.721656.X  0.322
1999 Barnham KJ, Torres AM, Alewood D, Alewood PF, Domagala T, Nice EC, Norton RS. Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor. Protein Science : a Publication of the Protein Society. 7: 1738-49. PMID 10082370 DOI: 10.1002/Pro.5560070808  0.356
1999 Miranda LP, Alewood PF. Accelerated chemical synthesis of peptides and small proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 1181-6. PMID 9989998 DOI: 10.1073/Pnas.96.4.1181  0.442
1999 TORRES AM, WANG X, FLETCHER JI, ALEWOOD D, ALEWOOD PF, SMITH R, SIMPSON RJ, NICHOLSON GM, SUTHERLAND SK, GALLAGHER CH, KING GF, KUCHEL PW. Solution structure of a defensin-like peptide from platypus venom Biochemical Journal. 341: 785. DOI: 10.1042/0264-6021:3410785  0.433
1999 Adams DJ, Alewood PF, Craik DJ, Drinkwater RD, Lewis RJ. Conotoxins and their potential pharmaceutical applications Drug Development Research. 46: 219-234. DOI: 10.1002/(Sici)1098-2299(199903/04)46:3/4<219::Aid-Ddr7>3.0.Co;2-S  0.536
1998 Hill JM, Oomen CJ, Miranda LP, Bingham JP, Alewood PF, Craik DJ. Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity. Biochemistry. 37: 15621-30. PMID 9843366 DOI: 10.1021/Bi981535W  0.362
1998 Wu QX, King MA, Donovan GR, Alewood D, Alewood P, Sawyer WH, Baldo BA. Cytotoxicity of pilosulin 1, a peptide from the venom of the jumper ant Myrmecia pilosula. Biochimica Et Biophysica Acta. 1425: 74-80. PMID 9813247 DOI: 10.1016/S0304-4165(98)00052-X  0.378
1998 Hu SH, Loughnan M, Miller R, Weeks CM, Blessing RH, Alewood PF, Lewis RJ, Martin JL. The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods. Biochemistry. 37: 11425-33. PMID 9708977 DOI: 10.1021/Bi9806549  0.412
1998 Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, Livett BG, Down JG, Jones A, Alewood PF, Lewis RJ. alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 273: 15667-74. PMID 9624161 DOI: 10.1074/Jbc.273.25.15667  0.557
1998 Gehrmann J, Alewood PF, Craik DJ. Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability. Journal of Molecular Biology. 278: 401-15. PMID 9571060 DOI: 10.1006/Jmbi.1998.1701  0.427
1998 Pallaghy PK, Alewood D, Alewood PF, Norton RS. Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus. Febs Letters. 419: 191-6. PMID 9428632 DOI: 10.1016/S0014-5793(97)01452-X  0.343
1998 Miranda LP, Jones A, Meutermans WDF, Alewood PF. p-Cresol As a Reversible Acylium Ion Scavenger in Solid-Phase Peptide Synthesis Journal of the American Chemical Society. 120: 1410-1420. DOI: 10.1021/Ja973322K  0.384
1997 Scanlon MJ, Naranjo D, Thomas L, Alewood PF, Lewis RJ, Craik DJ. Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA. Structure (London, England : 1993). 5: 1585-97. PMID 9438859 DOI: 10.1016/S0969-2126(97)00307-9  0.344
1997 Alewood P, Alewood D, Miranda L, Love S, Meutermans W, Wilson D. Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries. Methods in Enzymology. 289: 14-29. PMID 9353715 DOI: 10.1016/S0076-6879(97)89041-6  0.411
1997 Hu SH, Gehrmann J, Alewood PF, Craik DJ, Martin JL. Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI. Biochemistry. 36: 11323-30. PMID 9298951 DOI: 10.1021/Bi9713052  0.383
1997 Hill JM, Alewood PF, Craik DJ. Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry. Structure (London, England : 1993). 5: 571-83. PMID 9115446 DOI: 10.1016/S0969-2126(97)00212-8  0.341
1997 Skjaerbaek N, Nielsen KJ, Lewis RJ, Alewood P, Craik DJ. Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy. The Journal of Biological Chemistry. 272: 2291-9. PMID 8999936 DOI: 10.1074/Jbc.272.4.2291  0.368
1997 Hu SH, Gehrmann J, Guddat LW, Alewood PF, Craik DJ, Martin JL. The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus. Structure (London, England : 1993). 4: 417-23. PMID 8740364 DOI: 10.1016/S0969-2126(96)00047-0  0.403
1997 Meutermans WDF, Alewood PF, Bourne GT, Hawkins B, Smythe ML. Synthesis of α-aspartyl-containing cyclic peptides Letters in Peptide Science. 4: 79-84. DOI: 10.1023/A:1008878017315  0.41
1996 Nielsen KJ, Thomas L, Lewis RJ, Alewood PF, Craik DJ. A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. Journal of Molecular Biology. 263: 297-310. PMID 8913308 DOI: 10.1006/Jmbi.1996.0576  0.432
1996 Hill JM, Alewood PF, Craik DJ. Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Biochemistry. 35: 8824-35. PMID 8688418 DOI: 10.1021/Bi960073O  0.373
1996 Raftery MJ, Harrison CA, Alewood P, Jones A, Geczy CL. Isolation of the murine S100 protein MRP14 (14 kDa migration-inhibitory-factor-related protein) from activated spleen cells: characterization of post-translational modifications and zinc binding. The Biochemical Journal. 316: 285-93. PMID 8645219 DOI: 10.1042/Bj3160285  0.351
1996 Jones A, Bingham JP, Gehrmann J, Bond T, Loughnan M, Atkins A, Lewis RJ, Alewood PF. Isolation and characterization of conopeptides by high-performance liquid chromatography combined with mass spectrometry and tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 10: 138-43. PMID 8563013 DOI: 10.1002/(Sici)1097-0231(19960115)10:1<138::Aid-Rcm442>3.0.Co;2-3  0.337
1996 Taylor C, Quinn RJ, Alewood P. Synthesis of cyclic peptides modelled on the microcystin and nodularin rings Bioorganic & Medicinal Chemistry Letters. 6: 2107-2112. DOI: 10.1016/0960-894X(96)00377-0  0.392
1996 Englebretsen DR, Alewood PF. Boc SPPS of two hydrophobic peptides using a “solubilising tail” strategy: dodecaalanine and chemotactic protein 1042–55 Tetrahedron Letters. 37: 8431-8434. DOI: 10.1016/0040-4039(96)01910-7  0.421
1996 Meutermans WD, Alewood PF. A simple and effective procedure for the synthesis of the ‘difficult’ phosphotyrosine-containing peptide stat 91 (695–708) Tetrahedron Letters. 37: 4765-4766. DOI: 10.1016/0040-4039(96)00929-X  0.369
1995 Gooley AA, Pisano A, Packer NH, Ball M, Jones A, Alewood PF, Redmond JW, Williams KL. Characterization of a single glycosylated asparagine site on a glycopeptide using solid-phase Edman degradation. Glycoconjugate Journal. 11: 180-6. PMID 7841792 DOI: 10.1007/Bf00731216  0.323
1995 Englebretsen DR, Garnham BG, Bergman DA, Alewood PF. A novel thioether linker: Chemical synthesis of a HIV-1 protease analogue by thioether ligation Tetrahedron Letters. 36: 8871-8874. DOI: 10.1016/0040-4039(95)01843-7  0.409
1994 Monks SA, Gould AR, Lumley PE, Alewood PF, Kem WR, Goss NH, Norton RS. Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone. Biochimica Et Biophysica Acta. 1207: 93-101. PMID 7913833 DOI: 10.1016/0167-4838(94)90056-6  0.409
1994 Donovan GR, Street MD, Baldo BA, Alewood D, Alewood P, Sutherland S. Identification of an IgE-binding determinant of the major allergen Myr p I from the venom of the Australian jumper ant Myrmecia pilosula. Biochimica Et Biophysica Acta. 1204: 48-52. PMID 7508264 DOI: 10.1016/0167-4838(94)90031-0  0.398
1994 Nicholls I, Alewood P. Design, Synthesis, and Opioid Receptor Binding of Some Novel Benzazepine Constrained Leucine Enkephalin Mimetics Bioorganic Chemistry. 22: 300-317. DOI: 10.1006/Bioo.1994.1024  0.407
1993 Nicholls IA, Morrison SF, Brinkworth RI, Alewood PF, Andrews PR. Central nervous system receptor binding profiles of some 2-amino-4-phenyl quinolines: a novel class of alpha 2-adrenoceptor selective ligands. Life Sciences. 53: PL343-7. PMID 8412517 DOI: 10.1016/0024-3205(93)90568-N  0.348
1993 Alewood PF, Bailey AJ, Brinkworth RI, Fairlie D, Jones A. Characterisation of TNF-alpha-related peptides by high-performance liquid chromatography-mass spectrometry and high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography. 646: 185-91. PMID 8408427 DOI: 10.1016/S0021-9673(99)87020-4  0.315
1993 Grieve PA, Jones A, Alewood PF. Analytical methods for differentiating minor sequence variations in related peptides. Journal of Chromatography. 646: 175-84. PMID 8408426 DOI: 10.1016/S0021-9673(99)87019-8  0.388
1993 Nash K, Feldmuller M, de Jersey J, Alewood P, Hamilton S. Continuous and discontinuous assays for phosphotyrosyl protein phosphatase activity using phosphotyrosyl peptide substrates. Analytical Biochemistry. 213: 303-9. PMID 8238906 DOI: 10.1006/Abio.1993.1425  0.388
1993 Ball JB, Hughes RA, Alewood PF, Andrews PR. β-turn topography Tetrahedron. 49: 3467-3478. DOI: 10.1016/S0040-4020(01)90207-8  0.307
1992 Schnölzer M, Alewood P, Jones A, Alewood D, Kent SB. In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences. International Journal of Peptide and Protein Research. 40: 180-93. PMID 1478777 DOI: 10.1111/J.1399-3011.1992.Tb00291.X  0.345
1992 Schnölzer M, Jones A, Alewood PF, Kent SB. Ion-spray tandem mass spectrometry in peptide synthesis: structural characterization of minor by-products in the synthesis of ACP(65-74). Analytical Biochemistry. 204: 335-43. PMID 1443533 DOI: 10.1016/0003-2697(92)90249-7  0.376
1992 Valerio RM, Alewood PF, Perich JW, Tong G, Johns RB. Synthesis of the simple peptide model ac-abu(po3H2)-NHMe Australian Journal of Chemistry. 45: 777-784. DOI: 10.1071/Ch9920777  0.365
1992 Alewood PF, Brinkworth RI, Dancer RJ, Garnham B, Jones A, Kent SB. Solid phase synthesis of hydroxyethylamine peptide bond isosteres: Synthesis of the potent HIV-1 protease inhibitor JG365 Tetrahedron Letters. 33: 977-980. DOI: 10.1016/S0040-4039(00)91592-2  0.35
1991 Perich J, Valerio R, Alewood P, Johns R. Synthesis of Casein Related Peptides and Phosphopeptides. XIV. Solid Phase Synthesis of Glu-Ser(P)-Leu Through the Use of Protected Boc-Ser(PO3R2)-OH Derivatives Australian Journal of Chemistry. 44: 771. DOI: 10.1071/Ch9910771  0.399
1991 Perich JW, Alewood PF, Johns RB. Synthesis of casein-related peptides and phosphopeptides. ix. a modified method for the synthesis of ser(p) peptides by using ppoc-ser(PO) Australian Journal of Chemistry. 44: 377-387. DOI: 10.1071/Ch9910377  0.335
1991 Perich JW, Alewood PF, Johns RB. Synthesis of Casein-Related Peptides and Phosphopeptides. VII. The Efficient Synthesis of Ser(P)-Containing Peptides by the Use of Boc-Ser(PO Australian Journal of Chemistry. 44: 233-252. DOI: 10.1071/Ch9910233  0.384
1990 Ball JB, Andrews PR, Alewood PF, Hughes RA. A one-variable topographical descriptor for the β-turns of peptides and proteins Febs Letters. 273: 15-18. PMID 2226846 DOI: 10.1016/0014-5793(90)81040-U  0.386
1990 Ball JB, Alewood PF. Conformational constraints: nonpeptide beta-turn mimics Journal of Molecular Recognition : Jmr. 3: 55-64. PMID 2163268 DOI: 10.1002/Jmr.300030202  0.332
1989 Valerio RM, Perich JW, Kitas EA, Alewood PF, Johns RB. Synthesis of o-phosphotyrosine-containing peptides. II* solution-phase synthesis of asn-glu-PTyr-Thr-Ala through methyl phosphate protection Australian Journal of Chemistry. 42: 1519-1525. DOI: 10.1071/Ch9891519  0.349
1987 Perich JW, Alewood PF, Johns RB. Synthesis of casein-related peptides and phosphopeptides. I Solution-Phase Synthesis and 13C N.M.R. Spectroscopy of the Nα-Acetyl Octapeptide N-methylamide corresponding to region 14-21 of bovine β-Casein A2 Australian Journal of Chemistry. 40: 257-271. DOI: 10.1071/Ch9870257  0.376
Low-probability matches (unlikely to be authored by this person)
1989 Ball J, Craik D, Alewood P, Morrison S, Andrews P, Nicholls I. Synthesis and Conformational Analysis of the Slime-Mold Acrasin Glorin Australian Journal of Chemistry. 42: 2171. DOI: 10.1071/Ch9892171  0.3
2019 Ziegman R, Undheim EAB, Baillie G, Jones A, Alewood PF. Investigation of the estuarine stonefish (Synanceia horrida) venom composition. Journal of Proteomics. PMID 30953730 DOI: 10.1016/J.Jprot.2019.04.002  0.299
2010 Muttenthaler M, Andersson A, de Araujo AD, Dekan Z, Lewis RJ, Alewood PF. Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of Medicinal Chemistry. 53: 8585-96. PMID 21117646 DOI: 10.1021/Jm100989W  0.299
2017 Ma L, Chin YK, Dekan Z, Ikonomopoulou M, Herzig V, Chow CY, Alewood P, King GF. Novel Human Eag Channel Antagonists from Spider Venoms Biophysical Journal. 112: 332a. DOI: 10.1016/J.Bpj.2016.11.1800  0.298
1993 Baca M, Alewood PF, Kent SB. Structural engineering of the HIV-1 protease molecule with a beta-turn mimic of fixed geometry. Protein Science : a Publication of the Protein Society. 2: 1085-91. PMID 8358291 DOI: 10.1002/Pro.5560020702  0.298
1995 Bergman DA, Alewood D, Alewood PF, Andrews JL, Brinkworth RI, Englebretsen DR, Kent SBH. Kinetic properties of HIV-1 protease produced by total chemical synthesis with cysteine residues replaced by isosteric L-α-amino-n-butyric acid Letters in Peptide Science. 2: 99-107. DOI: 10.1007/Bf00128504  0.297
1999 Nielsen KJ, Skjaerbaek N, Dooley M, Adams DA, Mortensen M, Dodd PR, Craik DJ, Alewood PF, Lewis RJ. Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulators. Journal of Medicinal Chemistry. 42: 415-26. PMID 9986713 DOI: 10.1021/Jm981052Q  0.297
2014 Vink S, Daly NL, Steen N, Craik DJ, Alewood PF. Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon : Official Journal of the International Society On Toxinology. 90: 308-17. PMID 25172536 DOI: 10.1016/J.Toxicon.2014.08.068  0.297
2021 Armstrong DA, Jin AH, Braga Emidio N, Lewis RJ, Alewood PF, Rosengren KJ. Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from . Marine Drugs. 19. PMID 33530397 DOI: 10.3390/md19020060  0.295
2019 Dutt M, Dutertre S, Jin AH, Lavergne V, Alewood PF, Lewis RJ. Venomics Reveals Venom Complexity of the Piscivorous Cone Snail, . Marine Drugs. 17. PMID 30669642 DOI: 10.3390/Md17010071  0.295
2010 Muttenthaler M, Ramos YG, Feytens D, de Araujo AD, Alewood PF. p-Nitrobenzyl protection for cysteine and selenocysteine: a more stable alternative to the acetamidomethyl group. Biopolymers. 94: 423-32. PMID 20593464 DOI: 10.1002/Bip.21502  0.293
2013 Sadeghi M, Murali SS, Lewis RJ, Alewood PF, Mohammadi S, Christie MJ. Novel ω-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration. Molecular Pain. 9: 51. PMID 24139484 DOI: 10.1186/1744-8069-9-51  0.293
1996 Donovan GR, Street MD, Tetaz T, Smith AI, Alewood D, Alewood P, Sutherland SK, Baldo BA. Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products. Biochemistry and Molecular Biology International. 39: 877-85. PMID 8866004 DOI: 10.1080/15216549600201022  0.292
2015 Jouiaei M, Casewell NR, Yanagihara AA, Nouwens A, Cribb BW, Whitehead D, Jackson TN, Ali SA, Wagstaff SC, Koludarov I, Alewood P, Hansen J, Fry BG. Firing the sting: chemically induced discharge of cnidae reveals novel proteins and peptides from box jellyfish (Chironex fleckeri) venom. Toxins. 7: 936-50. PMID 25793725 DOI: 10.3390/Toxins7030936  0.292
2016 Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/Nature17976  0.29
2006 Lovelace ES, Armishaw CJ, Colgrave ML, Alewood PF, Daly NL, Craik DJ. Backbone cyclization improves the enzymatic stability of chi-conotoxin, MrIA, whilst maintaining its structure and NET-modulating activity Biopolymers. 80: 641-642. DOI: 10.1007/978-0-387-26575-9_283  0.289
2014 Dutertre S, Jin AH, Alewood PF, Lewis RJ. Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose. Toxicon : Official Journal of the International Society On Toxinology. 91: 135-44. PMID 25301479 DOI: 10.1016/J.Toxicon.2014.09.011  0.288
1997 Wade JD, Alewood PF. Peptides — From discovery to therapeutics Letters in Peptide Science. 4: 55-55. DOI: 10.1007/BF02443515  0.287
2013 de Araujo AD, Herzig V, Windley MJ, Dziemborowicz S, Mobli M, Nicholson GM, Alewood PF, King GF. Do vicinal disulfide bridges mediate functionally important redox transformations in proteins? Antioxidants & Redox Signaling. 19: 1976-80. PMID 23646911 DOI: 10.1089/Ars.2013.5365  0.286
1988 Valerio RM, Alewood PF, Johns RB. Synthesis of Optically Active 2-(tert-Butyloxycarbonylamino)-4-dialkoxyphosphorylbutanoate Protected Isosteres ofO-Phosphonoserine for Peptide Synthesis Synthesis. 1988: 786-789. DOI: 10.1055/S-1988-27707  0.285
1999 Harrison CA, Raftery MJ, Walsh J, Alewood P, Iismaa SE, Thliveris S, Geczy CL. Oxidation regulates the inflammatory properties of the murine S100 protein S100A8. The Journal of Biological Chemistry. 274: 8561-9. PMID 10085090 DOI: 10.1074/Jbc.274.13.8561  0.284
2006 Muttenthaler M, Alewood PF. Directed folding of alpha-conotoxins using selenocysteine Journal of Peptide Science. 12: 87-87. DOI: 10.1002/Psc.796  0.282
1998 Lackmann M, Harpur AG, Oates AC, Mann RJ, Gabriel A, Meutermans W, Alewood PF, Kerr IM, Stark GR, Wilks AF. Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes. Growth Factors (Chur, Switzerland). 16: 39-51. PMID 9777369 DOI: 10.3109/08977199809017490  0.282
2007 Chandrashekaran IR, Yao S, Wang CC, Bansal PS, Alewood PF, Forbes BE, Wallace JC, Bach LA, Norton RS. The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs. Biochemistry. 46: 3065-74. PMID 17305365 DOI: 10.1021/Bi0619876  0.281
2014 Prashanth JR, Brust A, Jin A, Alewood PF, Dutertre S, Lewis RJ. Erratum: Cone snail venomics: From novel biology to novel therapeutics (Future Medicinal Chemistry (2014) 6:15 (1659-1675)) Future Medicinal Chemistry. 6. DOI: 10.4155/Fmc.14.159  0.279
2010 PERICH JW, ALEWOOD PF, JOHNS RB. ChemInform Abstract: Synthesis of Casein-Related Peptides and Phosphopeptides. Part 7. The Efficient Synthesis of Ser(P)-Containing Peptides by the Use of Boc- Ser(PO3R2)-OH Derivatives Cheminform. 22: no-no. DOI: 10.1002/CHIN.199119256  0.279
2012 Holland JW, Gupta R, Deeth HC, Alewood PF. UHT milk contains multiple forms of α s1-casein that undergo degradative changes during storage Food Chemistry. 133: 689-696. DOI: 10.1016/J.Foodchem.2012.01.070  0.279
2001 Fry BG, Wickramaratna JC, Jones A, Alewood PF, Hodgson WC. Species and regional variations in the effectiveness of antivenom against the in vitro neurotoxicity of death adder (Acanthophis) venoms. Toxicology and Applied Pharmacology. 175: 140-8. PMID 11543646 DOI: 10.1006/Taap.2001.9233  0.279
2011 Vetter I, Davis JL, Rash LD, Anangi R, Mobli M, Alewood PF, Lewis RJ, King GF. Venomics: A new paradigm for natural products-based drug discovery Amino Acids. 40: 15-28. PMID 20177945 DOI: 10.1007/S00726-010-0516-4  0.278
1990 Ball JB, Wong MG, Capuano B, Gulbis JM, Mackay MF, Alewood PF. Syntheses and conformational analyses of some 3-amino-2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepine derivatives: X-ray crystal structure of 35-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepine Journal of Heterocyclic Chemistry. 27: 279-286. DOI: 10.1002/Jhet.5570270231  0.278
2010 PERICH JW, ALEWOOD PF, JOHNS RB. ChemInform Abstract: Synthesis of Casein-Related Peptides and Phosphopeptides. Part 9. A Modified Method for the Synthesis of Ser(P) Peptides by Using Ppoc-Ser( PO3Bzl2)-OH. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199125238  0.276
2006 Latham CF, Lopez JA, Hu SH, Gee CL, Westbury E, Blair DH, Armishaw CJ, Alewood PF, Bryant NJ, James DE, Martin JL. Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking. Traffic (Copenhagen, Denmark). 7: 1408-19. PMID 16899085 DOI: 10.1111/J.1600-0854.2006.00474.X  0.276
2002 Graudins A, Wilson D, Alewood PF, Broady KW, Nicholson GM. Cross-reactivity of Sydney funnel-web spider antivenom: neutralization of the in vitro toxicity of other Australian funnel-web (Atrax and Hadronyche) spider venoms. Toxicon : Official Journal of the International Society On Toxinology. 40: 259-66. PMID 11711122 DOI: 10.1016/S0041-0101(01)00210-0  0.276
1995 Gooley AA, Packer NH, Pisano A, Redmond JW, Williams KL, Jones A, Loughnan M, Alewood PF. Characterisation of individual N-and O-linked glycosylation sites using Edman degradation Techniques in Protein Chemistry. 6: 83-90. DOI: 10.1016/S1080-8914(06)80013-X  0.275
2000 Zhang B, Harness J, Somodevilla-Torres MJ, Hillyard NC, Mould AW, Alewood D, Love SG, Alewood PF, Greer JM, Cavanagh AC, McCombe PA, Morton H. Early pregnancy factor suppresses experimental autoimmune encephalomyelitis induced in Lewis rats with myelin basic protein and in SJL/J mice with myelin proteolipid protein peptide 139-151. Journal of the Neurological Sciences. 182: 5-15. PMID 11102634 DOI: 10.1016/S0022-510X(00)00432-9  0.274
1999 Harrison CA, Raftery MJ, Alewood P, Geczy CL. Structure/function studies of S100A8/A9 Letters in Peptide Science. 6: 359-369. DOI: 10.1007/Bf02443433  0.274
2014 Brust A, Gori A, Wang CA, Harvey PJ, Rosengren KJ, Gelmi ML, Longh R, Lewis RJ, Alewood PF. SELECTIVE FOLDING AND STABILIZATION OF A CYSTEINE RICH CONOTOXIN, MrIA AS A 1,2,3-TRIAZOLE-DISULFIDE BOND HYBRID Journal of Peptide Science. 20. DOI: 10.1002/Psc.2687  0.273
2016 Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I. Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain. Toxins. 8. PMID 26999206 DOI: 10.3390/Toxins8030078  0.271
2004 Ravasi T, Hsu K, Goyette J, Schroder K, Yang Z, Rahimi F, Miranda LP, Alewood PF, Hume DA, Geczy C. Probing the S100 protein family through genomic and functional analysis. Genomics. 84: 10-22. PMID 15203200 DOI: 10.1016/J.Ygeno.2004.02.002  0.27
2009 Mobli M, de Araújo AD, Lambert LK, Pierens GK, Windley MJ, Nicholson GM, Alewood PF, King GF. Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 48: 9312-4. PMID 19890933 DOI: 10.1002/Anie.200905206  0.266
2012 Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. A proteomic approach to detect lactosylation and other chemical changes in stored milk protein concentrate. Food Chemistry. 132: 655-62. PMID 26434346 DOI: 10.1016/J.Foodchem.2011.11.012  0.265
2011 Dekan Z, Vetter I, Daly N, Lewis R, Alewood P, Craik D. alpha-conotoxin ImI cystathionine 1-3 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr21007  0.265
2011 Dekan Z, Vetter I, Daly N, Lewis R, Alewood P, Craik D. alpha-conotoxin ImI cystathionine 2-4 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr21006  0.265
2010 Muttenthaler MM, Araujo ADd, Andersson A, Vetter I, Gruber C, Ramos YG, Feytens D, Bergmayr C, Freissmuth M, Lewis R, Alewood P. Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor Journal of Peptide Science. 16: 161-161. DOI: 10.1002/Psc.1303  0.265
2015 Murali SS, Napier IA, Mohammadi SA, Alewood PF, Lewis RJ, Christie MJ. High-voltage-activated calcium current subtypes in mouse DRG neurons adapt in a subpopulation-specific manner after nerve injury. Journal of Neurophysiology. 113: 1511-9. PMID 25505111 DOI: 10.1152/Jn.00608.2014  0.265
2011 Mobli M, Morgenstern D, King GF, Alewood PF, Muttenthaler M. Site-specific pK(a) determination of selenocysteine residues in selenovasopressin by using 77Se NMR spectroscopy. Angewandte Chemie (International Ed. in English). 50: 11952-5. PMID 22002840 DOI: 10.1002/Anie.201104169  0.264
2020 Mueller A, Dekan Z, Kaas Q, Agwa AJ, Starobova H, Alewood PF, Schroeder CI, Mobli M, Deuis JR, Vetter I. Mapping the Molecular Surface of the Analgesic Na1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions. Acs Pharmacology & Translational Science. 3: 535-546. PMID 32566918 DOI: 10.1021/acsptsci.0c00002  0.263
2023 Vink S, Akondi KB, Jin J, Poth K, Torres AM, Kuchel PW, Burke SL, Head GA, Alewood PF. Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor A. Molecules (Basel, Switzerland). 28. PMID 37049825 DOI: 10.3390/molecules28073063  0.263
2011 Holland JW, Gupta R, Deeth HC, Alewood PF. Proteomic analysis of temperature-dependent changes in stored UHT milk Journal of Agricultural and Food Chemistry. 59: 1837-1846. PMID 21322568 DOI: 10.1021/Jf104395V  0.263
2000 Meutermans WDF, Golding SW, Bourne GT, Miranda LP, Dooley MJ, Alewood PF, Smythe ML. ChemInform Abstract: Synthesis of Difficult Cyclic Peptides by Inclusion of a Novel Photolabile Auxiliary in a Ring Contraction Strategy Cheminform. 31: no-no. DOI: 10.1002/CHIN.200050264  0.263
2014 Kent SB, Alewood PF. Editorial overview: synthetic biomolecules. Current Opinion in Chemical Biology. 22: viii-xi. PMID 25438804 DOI: 10.1016/J.Cbpa.2014.09.037  0.262
2019 Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. 160: 1766-1780. PMID 31335646 DOI: 10.1097/J.Pain.0000000000001567  0.261
1995 Meutermans WD, Alewood PF. The solid phase synthesis of dihydro- and tetrahydroisoquinolines Tetrahedron Letters. 36: 7709-7712. DOI: 10.1016/0040-4039(95)01569-4  0.258
2007 Yang Z, Yan WX, Cai H, Tedla N, Armishaw C, Di Girolamo N, Wang HW, Hampartzoumian T, Simpson JL, Gibson PG, Hunt J, Hart P, Hughes JM, Perry MA, Alewood PF, et al. S100A12 provokes mast cell activation: a potential amplification pathway in asthma and innate immunity. The Journal of Allergy and Clinical Immunology. 119: 106-14. PMID 17208591 DOI: 10.1016/J.Jaci.2006.08.021  0.258
2003 Hodgson WC, Eriksson CO, Alewood PF, Fry BG. Comparison of the in vitro neuromuscular activity of venom from three Australian snakes (Hoplocephalus stephensi, Austrelaps superbus and Notechis scutatus): efficacy of tiger snake antivenom. Clinical and Experimental Pharmacology & Physiology. 30: 127-32. PMID 12603339 DOI: 10.1046/J.1440-1681.2003.03816.X  0.258
2006 Steen NA, Barker SC, Alewood PF. Proteins in the saliva of the Ixodida (ticks): pharmacological features and biological significance. Toxicon : Official Journal of the International Society On Toxinology. 47: 1-20. PMID 16364387 DOI: 10.1016/J.Toxicon.2005.09.010  0.257
2002 Fry BG, Wickramaratna JC, Hodgson WC, Alewood PF, Kini RM, Ho H, Wüster W. Electrospray liquid chromatography/mass spectrometry fingerprinting of Acanthophis (death adder) venoms: taxonomic and toxinological implications. Rapid Communications in Mass Spectrometry : Rcm. 16: 600-8. PMID 11870898 DOI: 10.1002/Rcm.613  0.256
2006 Wilson D, Alewood PF. Taxonomy of Australian Funnel-web spiders using rp-HPLC/ESI-MS profiling techniques. Toxicon : Official Journal of the International Society On Toxinology. 47: 614-27. PMID 16554080 DOI: 10.1016/J.Toxicon.2006.01.014  0.256
2012 Muttenthaler M, Dawson PE, Gruber CW, Bergmayr C, Freissmuth M, Andersson A, Vetter I, Dutertre S, Lewis RJ, Alewood PF. Novel sources for potent and selective GPCR modulators Journal of Peptide Science. 18. DOI: 10.1002/Psc.2447  0.255
1995 Nicholls IA, Craik DJ, Alewood PF. NMR and molecular modelling based conformational analysis of some N-alkyl 1- and 2-benzazepinones: useful central nervous system agent design motifs. Biochemical and Biophysical Research Communications. 205: 98-104. PMID 7999141 DOI: 10.1006/Bbrc.1994.2635  0.255
2011 Beaumont KA, Wong SS, Ainger SA, Liu YY, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Leonard JH, Sturm RA. Melanocortin MC1 receptor in human genetics and model systems European Journal of Pharmacology. 660: 103-110. PMID 21199646 DOI: 10.1016/J.Ejphar.2010.11.040  0.254
2012 Vetter I, Mozar CA, Durek T, Wingerd JS, Alewood PF, Christie MJ, Lewis RJ. Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells. Biochemical Pharmacology. 83: 1562-71. PMID 22410003 DOI: 10.1016/J.Bcp.2012.02.022  0.254
1986 Perich JW, Alewood PF, Johns RB. An Efficient One-Pot Synthesis ofN-Protected α-Amino-β-dialkoxyphosphinyloxy(diphenoxyphosphinyloxy)-carboxylic Acids (Phosphate-Group Esters ofO-PhosphorylatedN-Protected α-Amino-β-hydroxyamino Acids) Synthesis. 1986: 572-573. DOI: 10.1055/S-1986-31710  0.253
2010 Alewood P, Engelhard M, Kent SB. Chemical protein synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 513. PMID 20862718 DOI: 10.1002/Psc.1291  0.253
2000 Tyndall JD, Reid RC, Tyssen DP, Jardine DK, Todd B, Passmore M, March DR, Pattenden LK, Bergman DA, Alewood D, Hu SH, Alewood PF, Birch CJ, Martin JL, Fairlie DP. Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. Journal of Medicinal Chemistry. 43: 3495-504. PMID 11000004 DOI: 10.1021/Jm000013N  0.252
2010 Miranda L, Meutermans W, Smythe M, Alewood PF. ChemInform Abstract: 2-Hydroxy-6-nitrobenzaldehyde (Hnb): A Generic Acyl Transfer Auxiliary for Peptide Synthesis Cheminform. 33: no-no. DOI: 10.1002/chin.200248263  0.251
2012 Jin A, Dutertre S, Kaas Q, Lewis RJ, Alewood PF. 98. Transcriptomic and Peptidomic Characterisation of the Conus marmoreus Venom: Insights on Conopeptide Diversity and Venomic Processing Toxicon. 60: 144-145. DOI: 10.1016/J.Toxicon.2012.04.099  0.251
2010 VALERIO RM, PERICH JW, ALEWOOD PF, TONG G, JOHNS RB. ChemInform Abstract: Synthesis of the Simple Peptide Model Ac-Abu(PO3H2)-NHMe. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199230226  0.251
2007 Latham CF, Hu SH, Gee CL, Armishaw CJ, Alewood PF, James DE, Martin JL. Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 524-8. PMID 17554178 DOI: 10.1107/S1744309107022361  0.25
2005 Kennett EC, Bubb WA, Bansal P, Alewood P, Kuchel PW. NMR studies of exchange between intra- and extracellular glutathione in human erythrocytes. Redox Report : Communications in Free Radical Research. 10: 83-90. PMID 15949128 DOI: 10.1179/135100005X38860  0.249
1977 Rauk A, Alewood PF. A theoretical study of the Curtius rearrangement. The electronic structures and interconversions of the CHNO species Canadian Journal of Chemistry. 55: 1498-1510. DOI: 10.1139/V77-209  0.248
2010 SCHNOELZER M, ALEWOOD P, JONES A, ALEWOOD D, KENT SBH. ChemInform Abstract: In situ Neutralization in Boc-Chemistry - Solid Phase Peptide Synthesis. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199307265  0.245
2000 Somodevilla-Torres MJ, Hillyard NC, Morton H, Alewood D, Halliday JA, Alewood PF, Vesey DA, Walsh MD, Cavanagh AC. Preparation and characterization of polyclonal antibodies against human chaperonin 10 Cell Stress & Chaperones. 5: 14. DOI: 10.1379/1466-1268(2000)005<0014:Pacopa>2.0.Co;2  0.245
2005 Holland JW, Deeth HC, Alewood PF. Analysis of O-glycosylation site occupancy in bovine κ-casein glycoforms separated by two-dimensional gel electrophoresis Proteomics. 5: 990-1002. PMID 15693064 DOI: 10.1002/Pmic.200401098  0.241
2022 Cardoso FC, Pineda SS, Herzig V, Sunagar K, Shaikh NY, Jin AH, King GF, Alewood PF, Lewis RJ, Dutertre S. The Deadly Toxin Arsenal of the Tree-Dwelling Australian Funnel-Web Spiders. International Journal of Molecular Sciences. 23. PMID 36361863 DOI: 10.3390/ijms232113077  0.238
2013 Le TT, Holland JW, Bhandari B, Alewood PF, Deeth HC. Direct evidence for the role of Maillard reaction products in protein cross-linking in milk powder during storage International Dairy Journal. 31: 81-93. DOI: 10.1016/J.Idairyj.2013.02.013  0.237
1986 Johns RB, Alewood PF, Perich JW, Chaffee AL, MacLeod JK. Fast atom bombardment mass spectrometry of seryl- and O-phosphoseryl-containing peptides Tetrahedron Letters. 27: 4791-4794. DOI: 10.1016/S0040-4039(00)85066-2  0.232
2001 Brown S, Alewood P. Venom as a source of useful biologically active molecules. Emergency Medicine (Fremantle, W.a.). 13: 389-90. PMID 11554876 DOI: 10.1046/J.1035-6851.2001.00248.X  0.232
2013 Brust A, Sunagar K, Undheim EAB, Vetter I, Yang DC, Casewell NR, Jackson TNW, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, Fry BG. Differential evolution and neofunctionalization of snake venom metalloprotease domains (Molecular and Cellular Proteomics 2013, 12, (651-663)) Molecular and Cellular Proteomics. 12: 1488. DOI: 10.1074/Mcp.A112.023135  0.231
2022 Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastian A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, ... ... Alewood PF, et al. The structural conformation of the tachykinin domain drives the anti-tumoral activity of an octopus peptide in melanoma BRAF. British Journal of Pharmacology. PMID 35818835 DOI: 10.1111/bph.15923  0.231
1994 Lewis RJ, Holmes MJ, Alewood PF, Jones A. Ionspray mass spectrometry of ciguatoxin-1, maitotoxin-2 and -3, and related marine polyether toxins. Natural Toxins. 2: 56-63. PMID 8075894 DOI: 10.1002/Nt.2620020203  0.23
2009 VALERIO RM, ALEWOOD PF, JOHNS R, KEMP BE. Synthesis of O-phosphonotyrosyl peptides International Journal of Peptide and Protein Research. 33: 428-438. DOI: 10.1111/J.1399-3011.1989.TB00219.X  0.23
1974 Alewood PF, Benn M, Reinfried R. Cyclizations of Azidoformates to Tetrahydro-1,3-oxazin-2-ones and Oxazolidin-2-ones Canadian Journal of Chemistry. 52: 4083-4089. DOI: 10.1002/Chin.197515134  0.229
2014 Deuis JR, Lim YL, Rodrigues de Sousa S, Lewis RJ, Alewood PF, Cabot PJ, Vetter I. Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology. 16: 1324-32. PMID 24714523 DOI: 10.1093/Neuonc/Nou048  0.229
2000 Nielsen K, Adams D, Thomas L, Bond T, Alewood P, Craik D, Lewis R. w-conotoxin MVIIC from Conus magus Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4500  0.227
2018 Brust A, Wang CA, Daly NL, Kennerly J, Sadeghi M, Christie MJ, Lewis RJ, Mobli M, Alewood PF. Corrigendum: Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter. Angewandte Chemie (International Ed. in English). 57: 5203. PMID 29701320 DOI: 10.1002/Anie.201803138  0.223
2021 Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Dürrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, et al. Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chemical Science. 12: 4057-4062. PMID 34163676 DOI: 10.1039/d0sc05501h  0.222
1984 Alewood PF, Perich JW, Johns RB. Preparation of nα-(t-butoxycarbonyl)-O-(dibenzylphosphono)-l-serine Australian Journal of Chemistry. 37: 429-433. DOI: 10.1071/Ch9840429  0.22
1973 Alewood PF, Kazmaier PM, Rauk A. Electronic structure of carbonyl nitrenes. Mechanism of insertion and abstraction reactions Journal of the American Chemical Society. 95: 5466-5475. DOI: 10.1021/Ja00798A006  0.218
1984 Alewood PF, Johns RB, Hoogenraad NJ, Sutherland T. An Improved Synthesis ofN δ-(Phosphonoacetyl)-L-ornithine Synthesis. 1984: 403-404. DOI: 10.1055/S-1984-30852  0.217
1977 Alewood PF, Benn M, Wong J, Jones AJ. 3β-Azidoformate thermolysis as a method for functionalizing the 4α-methyl group of lanostan-3β-ol and similar systems Canadian Journal of Chemistry. 55: 2510-2516. DOI: 10.1002/Chin.197742353  0.216
1990 VALERIO RM, PERICH JW, KITAS EA, ALEWOOD PF, JOHNS RB. ChemInform Abstract: Synthesis of O-Phosphotyrosine-Containing Peptides. Part 2. Solution-Phase Synthesis of Asn-Glu-PTyr-Thr-Ala Through Methyl Phosphate Protection. Cheminform. 21. DOI: 10.1002/chin.199002303  0.215
1986 PERICH JW, ALEWOOD PF, JOHNS RB, VALERIO RM. ChemInform Abstract: Solution-Phase Synthesis of an O-Phosphoseryl-Containing Peptide Using Phenyl Phosphorotriester Protection. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198631312  0.212
2003 Torres A, Bansal P, Alewood P, Bursill J, Kuchel P, Vandenberg J. 1H Chemical Shift Assignments for CnErg1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5652  0.212
1987 PERICH JW, ALEWOOD PF, JOHNS RB. ChemInform Abstract: Synthesis of Casein-Related Peptides and Phosphopeptides. Part 1. Solution-Phase Synthesis and 13C NMR Spectroscopy of the Nα-Acetyl Octapeptide N-Methylamide (I) Corresponding to Region 14-21 of Bovine β-Casein A2. Cheminform. 18. DOI: 10.1002/chin.198734338  0.212
2020 Liu H, Gruber CW, Alewood PF, Möller A, Muttenthaler M. The oxytocin receptor signalling system and breast cancer: a critical review. Oncogene. PMID 32782397 DOI: 10.1038/S41388-020-01415-8  0.207
1989 VALERIO RM, ALEWOOD PF, JOHNS RB. ChemInform Abstract: Synthesis of Optically Active 2-(tert-Butyloxycarbonylamino)-4-dialkoxyphosphorylbutanoate-Protected Isosteres of O-Phosphonoserine for Peptide Synthesis. Cheminform. 20. DOI: 10.1002/chin.198909292  0.206
1983 Alewood PF, Johns RB, Valerio RM, Kemp BE. A Simple Preparation ofO-Phospho-L-tyrosine Synthesis. 1983: 30-31. DOI: 10.1055/S-1983-30206  0.206
1984 ALEWOOD PF, PERICH JW, JOHNS RB. ChemInform Abstract: PREPARATION OF Nα-(TERT-BUTOXYCARBONYL)-O-(DIBENZYLPHOSPHONO)-L-SERINE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198437236  0.202
2010 Alewood P. Solving the a-conotoxin folding problem Journal of Peptide Science. 16: 25-25. DOI: 10.1002/Psc.1300  0.197
2020 Dutt M, Giacomotto J, Ragnarsson L, Andersson A, Brust A, Deakan Z, Alewood PF, Lewis RJ. Re-evaluating the nirvana cabal deployed by piscivorous cone snails. Toxicon : Official Journal of the International Society On Toxinology. 177: S9-S10. PMID 32635128 DOI: 10.1016/J.Toxicon.2019.10.044  0.189
1986 Hoogenraad N, Totino N, Elmer H, Wraight C, Alewood P, Johns RB. Inhibition of intestinal citrulline synthesis causes severe growth retardation in rats. The American Journal of Physiology. 249: G792-9. PMID 4083357 DOI: 10.1152/ajpgi.1985.249.6.G792  0.189
2021 Himaya SWA, Jin AH, Hamilton B, Rai SK, Alewood P, Lewis RJ. Venom duct origins of prey capture and defensive conotoxins in piscivorous Conus striatus. Scientific Reports. 11: 13282. PMID 34168165 DOI: 10.1038/s41598-021-91919-4  0.184
1998 McCombe P, Morton H, Cavanagh A, Harness J, Nickson I, Alewood P. Early pregnancy factor, a chaperonin 10 homologue, aids in recovery of rats from experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 90: 58. DOI: 10.1016/S0165-5728(98)91527-2  0.182
2006 Kent S, Alewood P. Special Issue – Tribute to Bruce Merrifield International Journal of Peptide Research and Therapeutics. 13: 29-29. DOI: 10.1007/S10989-006-9051-2  0.176
1986 Perich JW, Alewood PF, Johns RB. Solution-phase synthesis of an O-phosphoseryl-containing peptide using phenyl phosphorotriester protection Tetrahedron Letters. 27: 1373-1376. DOI: 10.1016/S0040-4039(00)84262-8  0.173
2021 Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations. Toxins. 13. PMID 33672955 DOI: 10.3390/toxins13020146  0.16
2022 Herzig V, Chen YC, Chin YK, Dekan Z, Chang YW, Yu HM, Alewood PF, Chen CC, King GF. The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human Ca3.1 and Ca3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor. Biomedicines. 10. PMID 35625803 DOI: 10.3390/biomedicines10051066  0.147
1984 Alewood PF, Perich JW, Johns RB. A novel approach to phosphopeptide synthesis-preparation of glu-pser-leu Tetrahedron Letters. 25: 987-990. DOI: 10.1016/S0040-4039(01)80081-2  0.13
1990 BALL JB, WONG MG, CAPUANO B, GULBIS JM, MACKAY MF, ALEWOOD PF. ChemInform Abstract: Syntheses and Conformational Analyses of Some 3-Amino-2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepine Derivatives: X-Ray Crystal Structure of 3S-3-(((1,1-Dimethylethoxy)carbonyl)amino)-2,5-dioxo-2,3,4,5-tetrahydro-1H-1-benzazepine. Cheminform. 21. DOI: 10.1002/CHIN.199032209  0.127
1990 BALL JB, CRAIK DJ, ALEWOOD PF, MORRISON S, ANDREWS PR, NICHOLLS IA. ChemInform Abstract: Synthesis and Conformational Analysis of the Slime-Mould Acrasin Glorin. Cheminform. 21. DOI: 10.1002/CHIN.199015268  0.123
1984 ALEWOOD PF, PERICH JW, JOHNS RB. ChemInform Abstract: A NOVEL APPROACH TO PHOSPHOPEPTIDE SYNTHESIS - PREPARATION OF GLU-PSER-LEU Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198427334  0.121
2012 Le TT, Deeth HC, Bhandari B, Alewood PF, Holland JW. A proteomic approach to detect lactosylation and other chemical changes in stored milk protein concentrate Food Chemistry. 132: 655-662. DOI: 10.1016/j.foodchem.2011.11.012  0.12
1999 Harrison CA, Raftery MJ, Alewood P, Geczy CL. Letters in Peptide Science. 6: 359-369. DOI: 10.1023/A:1008971021016  0.12
1999 Wade JD, Alewood PF, Nice E. Letters in Peptide Science. 6: 263-263. DOI: 10.1023/A:1008927131528  0.12
1997 Meutermans WD, Alewood PF, Bourne GT, Hawkins B, Smythe ML. Letters in Peptide Science. 4: 79-84. DOI: 10.1023/A:1008878017315  0.12
2019 Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen. Pain. PMID 30908355 DOI: 10.1097/j.pain.0000000000001567  0.117
1986 PERICH JW, ALEWOOD PF, JOHNS RB. ChemInform Abstract: An Efficient One-Pot Synthesis of N-Protected α-Amino-β-dialkoxyphosphinyloxy- (diphenoxyphosphinyloxy)carboxylic Acids (Phosphate-Group Esters of O-Phosphorylated N-Protected α-Amino-β-hydroxyamino Acids). Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198651312  0.116
2010 KENT SBH, ALEWOOD D, ALEWOOD P, BACA M, JONES A, SCHNOLZER M. ChemInform Abstract: Total Chemical Synthesis of Proteins: Evolution of Solid Phase Synthetic Methods Illustrated by Total Chemical Synthesis of the HIV-1 Protease Cheminform. 24: no-no. DOI: 10.1002/CHIN.199329315  0.112
2012 Smith JJ, Jones A, Alewood PF. Mass landscapes of seven scorpion species: The first analyses of Australian species with 1,5-DAN matrix. Journal of Venom Research. 3: 7-14. PMID 23236582  0.106
2010 NICHOLLS IA, ALEWOOD PF, BRINKWORTH RI, MORRISON SF, ANDREWS PR. ChemInform Abstract: 2-Substituted 1,3-Benzodiazocines: Design, Synthesis and Evaluation as Potential Central Nervous System Active Agents. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199406183  0.102
2015 Lavergne V, Harliwong I, Jones A, Miller D, Taft RJ, Alewood PF. Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks Proceedings of the National Academy of Sciences of the United States of America. 112: E3782-E3791. DOI: 10.1073/pnas.1501334112  0.096
1999 Wade JD, Alewood PF, Nice E. Peptides—from discovery to therapeutics Letters in Peptide Science. 6: 263-263. DOI: 10.1007/BF02443420  0.091
1978 ALEWOOD PF, HUSSAIN SA, JENKINS TC, PERKINS MJ, SHARMA AH, SIEW NPY, WARD P. ChemInform Abstract: ACYL NITROXIDES. PART I. SYNTHESIS AND ISOLATION Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197850107  0.087
1982 Wirth PJ, Alewood P, Calder I, Thorgeirsson SS. Mutagenicity of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin and their respective deacetylated metabolites in nitroreductase deficient Salmonella TA98FR and TA100FR. Carcinogenesis. 3: 167-70. PMID 6896016 DOI: 10.1093/carcin/3.2.167  0.085
2002 Lawrenson ID, Wimmer-Kleikamp SH, Lock P, Schoenwaelder SM, Down M, Boyd AW, Alewood PF, Lackmann M. Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling. Journal of Cell Science. 115: 1059-72. PMID 11870224  0.084
1984 Valerio R, Alewood P, Johns R, Kemp B. Synthesis of protected derivatives of O-phosphotyrosine incorporation in a heptapeptide Tetrahedron Letters. 25: 2609-2612. DOI: 10.1016/S0040-4039(01)81243-0  0.083
1984 VALERIO RM, ALEWOOD PF, JOHNS RB, KEMP BE. ChemInform Abstract: SYNTHESIS OF PROTECTED DERIVATIVES OF O-PHOSPHOTYROSINE. INCORPORATION IN A HEPTAPEPTIDE Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198441315  0.083
1983 ALEWOOD PF, PERICH JW, JOHNS RB. ChemInform Abstract: SYNTHESIS OF A PROTECTED PHOSPHOAMINO ACID, Nα-TERT-BUTYLOXYCARBONYL-O-DIETHYLPHOSPHORO-L-SERINE Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198318302  0.079
2001 Miranda LP, Alewood PF. ChemInform Abstract: Challenges for Protein Chemical Synthesis in the 21th Century: Bridging Genomics and Proteomics Cheminform. 32: no-no. DOI: 10.1002/CHIN.200115274  0.079
1982 Alewood PF, Perich JW, Johns RB. Synthesis of a Protected Phosphoamino Acid Nα-Teri-Butyloxycarbonyl-O-Diethylphosphoro-L-Serine Synthetic Communications. 12: 821-828. DOI: 10.1080/00397918208061923  0.078
1985 Alewood PF, Calder IC, Fernando R, Healey K, Richardson R. N-acetyl-N-oxo-1,4-benzoquinone imine, observation of an acyl nitrone Tetrahedron Letters. 26: 2467-2470. DOI: 10.1016/S0040-4039(00)94855-X  0.067
2010 ALEWOOD P, ALEWOOD D, MIRANDA L, LOVE S, MEUTERMANS W, WILSON D. ChemInform Abstract: Rapid in situ Neutralization Protocols for Boc and Fmoc Solid-Phase Chemistry Cheminform. 29: no-no. DOI: 10.1002/CHIN.199812284  0.067
1984 ALEWOOD PF, JOHNS RB, HOOGENRAAD NJ, SUTHERLAND T. ChemInform Abstract: AN IMPROVED SYNTHESIS OF NΔ-(PHOSPHONOACETYL)-L-ORNITHINE Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198442258  0.061
1975 ALEWOOD PF, BENN M, REINFRIED R. ChemInform Abstract: CYCLIZATIONS OF AZIDOFORMATES TO TETRAHYDRO-1,3-OXAZIN-2-ONES AND OXAZOLIDIN-2-ONES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197515134  0.061
1977 ALEWOOD PF, BENN M, WONG J, JONES AJ. ChemInform Abstract: 3β-AZIDOFORMATE THERMOLYSIS AS A METHOD FOR FUNCTIONALIZING THE 4α-METHYL GROUP OF LANOSTAN-3β-OL AND SIMILAR SYSTEMS Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197742353  0.057
1981 ALEWOOD PF, CALDER IC, RICHARDSON RL. ChemInform Abstract: AN IMPROVED PREPARATION OF N-(TERT-BUTYL)-N-(3,5-DINITROBENZOYL)NITROXYL Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198122147  0.057
1985 ALEWOOD PF, CALDER IC, FERNANDO R, HEALEY K, RICHARDSON R. ChemInform Abstract: N-ACETYL-N-OXO-1,4-BENZOQUINONE IMINE, OBSERVATION OF AN ACYL NITRONE Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198537156  0.055
1976 Jones AJ, Alewood PF, Benn M, Wong J. Functionalisation of the 4α-methyl group of lanostanol via azidoformate thermolysis Tetrahedron Letters. 17: 1655-1658. DOI: 10.1016/S0040-4039(00)92915-0  0.052
1981 Alewood PF, Calder IC, Richardson RL. An Improved Preparation ofN-(t-Butyl)-N-(3,5-dinitrobenzoyl)-nitroxyl Synthesis. 1981: 121-122. DOI: 10.1055/s-1981-29354  0.051
1983 ALEWOOD PF, JOHNS RB, VALERIO RM, KEMP BE. ChemInform Abstract: A SIMPLE PREPARATION OF O-PHOSPHO-L-TYROSINE Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198321261  0.049
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