| Year |
Citation |
Score |
| 2019 |
Guo H, Li Y, Shen L, Wang T, Jia X, Liu L, Xu T, Ou M, Hoekzema K, Wu H, Gillentine MA, Liu C, Ni H, Peng P, Zhao R, ... ... Adams DJ, et al. Disruptive variants of associate with autism and interfere with neuronal development and synaptic transmission. Science Advances. 5: eaax2166. PMID 31579823 DOI: 10.1126/sciadv.aax2166 |
1 |
|
| 2019 |
Shin B, Won H, Adams DJ, Lee SK. CD55 regulates bone mass in mice by modulating RANKL-mediated Rac signaling and osteoclast function. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31487060 DOI: 10.1002/jbmr.3861 |
0.32 |
|
| 2019 |
Draper ER, Wilbraham L, Adams DJ, Wallace M, Schweins R, Zwijnenburg MA. Insight into the self-assembly of water-soluble perylene bisimide derivatives through a combined computational and experimental approach. Nanoscale. PMID 31414112 DOI: 10.1039/c9nr03898a |
0.36 |
|
| 2019 |
Newell F, Kong Y, Wilmott JS, Johansson PA, Ferguson PM, Cui C, Li Z, Kazakoff SH, Burke H, Dodds TJ, Patch AM, Nones K, Tembe V, Shang P, van der Weyden L, ... ... Adams DJ, et al. Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets. Nature Communications. 10: 3163. PMID 31320640 DOI: 10.1038/s41467-019-11107-x |
0.44 |
|
| 2019 |
Pooja D, Gunukula A, Gupta N, Adams DJ, Kulhari H. Bombesin Receptors as Potential Targets for Anticancer Drug Delivery and Imaging. The International Journal of Biochemistry & Cell Biology. 105567. PMID 31295552 DOI: 10.1016/j.biocel.2019.105567 |
1 |
|
| 2019 |
Kulhari H, Jangid AK, Adams DJ. Monoclonal Antibody-Conjugated Dendritic Nanostructures for siRNA Delivery. Methods in Molecular Biology (Clifton, N.J.). 1974: 195-201. PMID 31099004 DOI: 10.1007/978-1-4939-9220-1_14 |
1 |
|
| 2019 |
Yu R, Tae HS, Xu Q, Craik DJ, Adams DJ, Jiang T, Kaas Q. Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British Journal of Pharmacology. PMID 31062355 DOI: 10.1111/bph.14698 |
1 |
|
| 2019 |
McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic TRPV1-active compounds inhibit native and recombinant T-type (Ca 3) calcium channels. British Journal of Pharmacology. PMID 30927254 DOI: 10.1111/bph.14676 |
1 |
|
| 2019 |
Angelerou MGF, Frederix PWJM, Wallace M, Yang B, Rodger A, Adams DJ, Marlow M, Zelzer M. Correction to "Supramolecular Nucleoside-Based Gel: Molecular Dynamics Simulation and Characterization of Its Nanoarchitecture and Self-Assembly Mechanism". Langmuir : the Acs Journal of Surfaces and Colloids. PMID 30730748 DOI: 10.1021/acs.langmuir.9b00009 |
0.36 |
|
| 2018 |
Harvey PJ, Kurniawan ND, Finol-Urdaneta RK, McArthur JR, Van Lysebetten D, Dash TS, Hill JM, Adams DJ, Durek T, Craik DJ. NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced Na Channel Potency. Molecules (Basel, Switzerland). 23. PMID 30360356 DOI: 10.3390/molecules23102715 |
1 |
|
| 2018 |
Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q. α-Conotoxin Vc1.1 Variants Target N-type Calcium Channels via GABA Receptor Activation and Display Improved Analgesic Activity. Journal of Medicinal Chemistry. PMID 30358401 DOI: 10.1021/acs.jmedchem.8b01343 |
1 |
|
| 2018 |
Draper ER, Wallace M, Honecker D, Adams DJ. Aligning self-assembled perylene bisimides in a magnetic field. Chemical Communications (Cambridge, England). PMID 30209449 DOI: 10.1039/c8cc05968c |
0.36 |
|
| 2018 |
Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports. 8: 13397. PMID 30194442 DOI: 10.1038/s41598-018-31245-4 |
1 |
|
| 2018 |
Heyman B, Rizzieri D, Adams DJ, Carlos De Castro, Diehl L, Li Z, Moore J, Beaven A. Phase I Study of the Combination of Bendamustine, Rituximab, and Pixantrone in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma. Clinical Lymphoma, Myeloma & Leukemia. PMID 30166257 DOI: 10.1016/j.clml.2018.07.285 |
0.44 |
|
| 2018 |
Elitt MS, Shick HE, Madhavan M, Allan KC, Clayton BLL, Weng C, Miller TE, Factor DC, Barbar L, Nawash BS, Nevin ZS, Lager AM, Li Y, Jin F, Adams DJ, et al. Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease. Stem Cell Reports. PMID 30146490 DOI: 10.1016/j.stemcr.2018.07.015 |
0.32 |
|
| 2018 |
Hubler Z, Allimuthu D, Bederman I, Elitt MS, Madhavan M, Allan KC, Shick HE, Garrison E, T Karl M, Factor DC, Nevin ZS, Sax JL, Thompson MA, Fedorov Y, Jin J, ... ... Adams DJ, et al. Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. Nature. PMID 30046109 DOI: 10.1038/s41586-018-0360-3 |
0.32 |
|
| 2018 |
Wu X, Tae HS, Huang YH, Adams DJ, Craik DJ, Kaas Q. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology. PMID 30009767 DOI: 10.1016/j.bcp.2018.07.007 |
1 |
|
| 2018 |
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/acschembio.8b00190 |
1 |
|
| 2018 |
Yu R, Tae HS, Tabassum N, Shi J, Jiang T, Adams DJ. Molecular determinants conferring the stoichiometric-dependent activity of α-conotoxins at the human α9α10 nicotinic acetylcholine receptor subtype. Journal of Medicinal Chemistry. PMID 29733583 DOI: 10.1021/acs.jmedchem.8b00115 |
1 |
|
| 2018 |
Wallace M, Adams DJ, Iggo JA. Titrations without the Additions: The Efficient Determination of pKValues Using NMR Imaging Techniques. Analytical Chemistry. PMID 29481064 DOI: 10.1021/acs.analchem.8b00181 |
0.36 |
|
| 2018 |
Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Contribution of membrane receptor signalling to chronic visceral pain. The International Journal of Biochemistry & Cell Biology. PMID 29477359 DOI: 10.1016/j.biocel.2018.02.017 |
1 |
|
| 2018 |
Liu Z, Bartels P, Sadeghi M, Du T, Dai Q, Zhu C, Yu S, Wang S, Dong M, Sun T, Guo J, Peng S, Jiang L, Adams DJ, Dai Q. A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity. Scientific Reports. 8: 1004. PMID 29343689 DOI: 10.1038/s41598-017-18479-4 |
1 |
|
| 2017 |
Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R. Role of Cys-Cys Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors. Acs Omega. 2: 4621-4631. PMID 30023726 DOI: 10.1021/acsomega.7b00639 |
1 |
|
| 2017 |
Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology. PMID 29194563 DOI: 10.1111/bph.14115 |
1 |
|
| 2017 |
Durek T, Shelukhina IV, Tae HS, Thongyoo P, Spirova EN, Kudryavtsev DS, Kasheverov IE, Faure G, Corringer PJ, Craik DJ, Adams DJ, Tsetlin VI. Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports. 7: 16606. PMID 29192197 DOI: 10.1038/s41598-017-16809-0 |
1 |
|
| 2017 |
Adams DJ, Lewis RJ. Neuropharmacology of venom peptides. Neuropharmacology. PMID 29154773 DOI: 10.1016/j.neuropharm.2017.11.025 |
1 |
|
| 2017 |
Hoggard MF, Rodriguez AM, Cano H, Clark E, Tae HS, Adams DJ, Godenschwege TA, Marí F. In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens. Neuropharmacology. PMID 28917942 DOI: 10.1016/j.neuropharm.2017.09.020 |
1 |
|
| 2017 |
Wu X, Huang YH, Kaas Q, Harvey PJ, Wang CK, Tae HS, Adams DJ, Craik DJ. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. The Journal of Biological Chemistry. PMID 28851841 DOI: 10.1074/jbc.M117.808386 |
1 |
|
| 2017 |
Kulhari H, Telukutla SR, Pooja D, Shukla R, Sistla R, Bansal V, Adams DJ. Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma. Nanomedicine (London, England). PMID 28635550 DOI: 10.2217/nnm-2017-0067 |
1 |
|
| 2017 |
McArthur JR, Motin L, Gleeson EC, Spiller S, Lewis RJ, Duggan PJ, Tuck KL, Adams DJ. Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1. British Journal of Pharmacology. PMID 28608537 DOI: 10.1111/bph.13910 |
1 |
|
| 2017 |
Jiang S, Tae HS, Xu S, Shao X, Adams DJ, Wang C. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor. Marine Drugs. 15. PMID 28598389 DOI: 10.3390/md15060170 |
1 |
|
| 2017 |
Yang L, Tae HS, Fan Z, Shao X, Xu S, Zhao S, Adams DJ, Wang C. A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA. Marine Drugs. 15. PMID 28587231 DOI: 10.3390/md15060164 |
1 |
|
| 2017 |
Ardoña HAM, Draper ER, Citossi F, Wallace M, Serpell LC, Adams DJ, Tovar JD. Kinetically-Controlled Coassembly of Multichromophoric Peptide Hydrogelators and the Impacts on Energy Transport. Journal of the American Chemical Society. PMID 28578581 DOI: 10.1021/jacs.7b04006 |
0.36 |
|
| 2017 |
Sadeghi M, McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons. Neuropharmacology. PMID 28533165 DOI: 10.1016/j.neuropharm.2017.05.020 |
1 |
|
| 2017 |
Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ. α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. British Journal of Pharmacology. PMID 28477355 DOI: 10.1111/bph.13852 |
1 |
|
| 2017 |
Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/s41598-017-01129-0 |
1 |
|
| 2017 |
Draper E, Wallace M, Schweins R, Poole RJ, Adams DJ. Non-Linear Effects in Multicomponent Supramolecular Hydrogels. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28191979 DOI: 10.1021/acs.langmuir.7b00326 |
0.36 |
|
| 2017 |
Wallace M, Iggo JA, Adams DJ. Probing the surface chemistry of self-assembled peptide hydrogels using solution-state NMR spectroscopy. Soft Matter. PMID 28165092 DOI: 10.1039/c6sm02404a |
0.36 |
|
| 2016 |
Draper ER, Lee JR, Wallace M, Jäckel F, Cowan AJ, Adams DJ. Self-sorted photoconductive xerogels. Chemical Science. 7: 6499-6505. PMID 28451108 DOI: 10.1039/c6sc02644c |
0.36 |
|
| 2016 |
Castilla AM, Wallace M, Mears LL, Draper ER, Doutch J, Rogers S, Adams DJ. On the syneresis of an OPV functionalised dipeptide hydrogel. Soft Matter. 12: 7848-7854. PMID 27714311 DOI: 10.1039/c6sm01194b |
0.36 |
|
| 2016 |
Pooja D, Kulhari H, Kuncha M, Rachamalla SS, Adams DJ, Bansal V, Sistla R. Improving efficacy, oral bioavailability and delivery of paclitaxel using protein-grafted solid lipid nanoparticles. Molecular Pharmaceutics. PMID 27696858 DOI: 10.1021/acs.molpharmaceut.6b00691 |
1 |
|
| 2016 |
Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. The Journal of Biological Chemistry. PMID 27646000 DOI: 10.1074/jbc.M116.730804 |
1 |
|
| 2016 |
Berecki G, Motin L, Adams DJ. Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H. Neuropharmacology. PMID 27245500 DOI: 10.1016/j.neuropharm.2016.05.019 |
1 |
|
| 2016 |
Pooja D, Kulhari H, Adams DJ, Sistla R. Formulation and dosage of therapeutic nanosuspension for active targeting of docetaxel (WO 2014210485A1). Expert Opinion On Therapeutic Patents. PMID 27088623 DOI: 10.1080/13543776.2016.1180365 |
1 |
|
| 2016 |
Kulhari H, Pooja D, Shrivastava S, Kuncha M, Naidu VG, Bansal V, Sistla R, Adams DJ. Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer. Scientific Reports. 6: 23179. PMID 27052896 DOI: 10.1038/srep23179 |
1 |
|
| 2016 |
Carstens BB, Swedberg J, Berecki G, Adams DJ, Craik DJ, Clark RJ. Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers. PMID 27038328 DOI: 10.1002/bip.22848 |
1 |
|
| 2016 |
Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/anie.201600297 |
1 |
|
| 2016 |
Kulhari H, Pooja D, Kota R, Telukutla SR, Tabor RF, Shukla R, Adams DJ, Sistla R, Bansal V. Cyclic RGDfK Peptide Functionalized Polymeric Nanocarriers for Targeting Gemcitabine to Ovarian Cancer Cells. Molecular Pharmaceutics. PMID 26930230 DOI: 10.1021/acs.molpharmaceut.5b00935 |
1 |
|
| 2016 |
Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut. PMID 26887818 DOI: 10.1136/gutjnl-2015-310971 |
1 |
|
| 2015 |
Motin L, Durek T, Adams DJ. Modulation of Human Nav1.7 Channel Gating by Synthetic α-Scorpion Toxin OD1 and its Analogues. Channels (Austin, Tex.). 0. PMID 26646206 DOI: 10.1080/19336950.2015.1120392 |
1 |
|
| 2015 |
Berecki G, Motin L, Adams DJ. R-type (Cav2.3) Calcium Channel Inhibition Via Human μ- δ- and κ-Opioid Receptors is Voltage-Independently Mediated by Gβγ Protein Subunits. Molecular Pharmacology. PMID 26490245 DOI: 10.1124/mol.115.101154 |
1 |
|
| 2015 |
Hassan-Puttaswamy V, Adams DJ, Kini RM. A Distinct Functional Site in Ω-Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom. Acs Chemical Biology. PMID 26448325 DOI: 10.1021/acschembio.5b00492 |
1 |
|
| 2015 |
Kompella SN, Cuny H, Hung A, Adams DJ. Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors. Molecular Pharmacology. 88: 993-1001. PMID 26438212 DOI: 10.1124/mol.115.100503 |
1 |
|
| 2015 |
Xu S, Zhang T, Kompella SN, Yan M, Lu A, Wang Y, Shao X, Chi C, Adams DJ, Ding J, Wang C. Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Scientific Reports. 5: 14261. PMID 26395518 DOI: 10.1038/srep14261 |
1 |
|
| 2015 |
Kulhari H, Pooja D, Singh MK, Kuncha M, Adams DJ, Sistla R. Bombesin-conjugated nanoparticles improve the cytotoxic efficacy of docetaxel against gastrin-releasing but androgen-independent prostate cancer. Nanomedicine (London, England). 10: 2847-59. PMID 26377157 DOI: 10.2217/nnm.15.107 |
1 |
|
| 2015 |
Yu R, Seymour VA, Berecki G, Jia X, Akcan M, Adams DJ, Kaas Q, Craik DJ. Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports. 5: 13264. PMID 26290113 DOI: 10.1038/srep13264 |
1 |
|
| 2015 |
Akcan M, Clark RJ, Daly NL, Conibear AC, de Faoite A, Heghinian MD, Sahil T, Adams DJ, Marí F, Craik DJ. Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins. Biopolymers. PMID 26172377 DOI: 10.1002/bip.22699 |
1 |
|
| 2015 |
Kulhari H, Pooja D, Shrivastava S, Telukutala SR, Barui AK, Patra CR, Naidu VG, Adams DJ, Sistla R. Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 25933692 DOI: 10.1016/j.nano.2015.04.007 |
1 |
|
| 2015 |
Kulhari H, Pooja D, Rompicharla SV, Sistla R, Adams DJ. Biomedical Applications of Trastuzumab: As a Therapeutic Agent and a Targeting Ligand. Medicinal Research Reviews. 35: 849-76. PMID 25847027 DOI: 10.1002/med.21345 |
1 |
|
| 2015 |
Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/jacs.5b00244 |
1 |
|
| 2015 |
Heghinian MD, Mejia M, Adams DJ, Godenschwege TA, Marí F. Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1011-8. PMID 25466886 DOI: 10.1096/fj.14-262733 |
1 |
|
| 2015 |
Huynh TG, Cuny H, Slesinger PA, Adams DJ. Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor. Molecular Pharmacology. 87: 240-50. PMID 25425625 DOI: 10.1124/mol.114.096156 |
1 |
|
| 2015 |
Kompella SN, Hung A, Clark RJ, Marí F, Adams DJ. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. The Journal of Biological Chemistry. 290: 1039-48. PMID 25411242 DOI: 10.1074/jbc.M114.605592 |
1 |
|
| 2015 |
Vetter I, Hodgson WC, Adams DJ, McIntyre P. Venoms-based drug discovery: Bioassays, electrophysiology, high-throughput screens and target identincation Rsc Drug Discovery Series. 2015: 97-128. |
1 |
|
| 2014 |
Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. Journal of Medicinal Chemistry. 57: 9933-44. PMID 25393758 DOI: 10.1021/jm501126u |
1 |
|
| 2014 |
Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42. PMID 25101833 DOI: 10.1016/j.bcp.2014.07.025 |
1 |
|
| 2014 |
Berecki G, McArthur JR, Cuny H, Clark RJ, Adams DJ. Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation. The Journal of General Physiology. 143: 465-79. PMID 24688019 DOI: 10.1085/jgp.201311104 |
1 |
|
| 2014 |
Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology. 171: 3313-27. PMID 24628243 DOI: 10.1111/bph.12686 |
1 |
|
| 2014 |
Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochemical Pharmacology. 89: 276-86. PMID 24561180 DOI: 10.1016/j.bcp.2014.02.008 |
1 |
|
| 2013 |
Kabbani N, Nordman JC, Corgiat BA, Veltri DP, Shehu A, Seymour VA, Adams DJ. Are nicotinic acetylcholine receptors coupled to G proteins? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 1025-34. PMID 24185813 DOI: 10.1002/bies.201300082 |
1 |
|
| 2013 |
Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/jbc.M113.512582 |
1 |
|
| 2013 |
Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/j.bcp.2013.07.016 |
1 |
|
| 2013 |
van Lierop BJ, Robinson SD, Kompella SN, Belgi A, McArthur JR, Hung A, MacRaild CA, Adams DJ, Norton RS, Robinson AJ. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chemical Biology. 8: 1815-21. PMID 23768016 DOI: 10.1021/cb4002393 |
1 |
|
| 2013 |
Yu R, Kompella SN, Adams DJ, Craik DJ, Kaas Q. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry. 56: 3557-67. PMID 23566299 DOI: 10.1021/jm400041h |
1 |
|
| 2013 |
Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. Acs Chemical Biology. 8: 1215-22. PMID 23527544 DOI: 10.1021/cb400012k |
1 |
|
| 2013 |
Yasuda T, Cuny H, Adams DJ. Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation. The Journal of Physiology. 591: 2579-91. PMID 23478135 DOI: 10.1113/jphysiol.2012.249151 |
1 |
|
| 2013 |
Adams DJ, Berecki G. Mechanisms of conotoxin inhibition of N-type (Ca(v)2.2) calcium channels. Biochimica Et Biophysica Acta. 1828: 1619-28. PMID 23380425 DOI: 10.1016/j.bbamem.2013.01.019 |
1 |
|
| 2012 |
Knapp O, McArthur JR, Adams DJ. Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics? Toxins. 4: 1236-60. PMID 23202314 DOI: 10.3390/toxins4111236 |
1 |
|
| 2012 |
Rupasinghe DB, Knapp O, Blomster LV, Schmid AB, Adams DJ, King GF, Ruitenberg MJ. Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function. Channels (Austin, Tex.). 6: 103-10. PMID 22622154 DOI: 10.4161/chan.19484 |
1 |
|
| 2012 |
Cuny H, de Faoite A, Huynh TG, Yasuda T, Berecki G, Adams DJ. γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxins. The Journal of Biological Chemistry. 287: 23948-57. PMID 22613715 DOI: 10.1074/jbc.M112.342998 |
1 |
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| 2012 |
Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochemical Pharmacology. 84: 540-8. PMID 22609441 DOI: 10.1016/j.bcp.2012.05.008 |
1 |
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| 2012 |
Knapp O, Nevin ST, Yasuda T, Lawrence N, Lewis RJ, Adams DJ. Biophysical properties of Na(v) 1.8/Na(v) 1.2 chimeras and inhibition by µO-conotoxin MrVIB. British Journal of Pharmacology. 166: 2148-60. PMID 22452751 DOI: 10.1111/j.1476-5381.2012.01955.x |
1 |
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| 2012 |
Napier IA, Klimis H, Rycroft BK, Jin AH, Alewood PF, Motin L, Adams DJ, Christie MJ. Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain. Neuropharmacology. 62: 2202-7. PMID 22306793 DOI: 10.1016/j.neuropharm.2012.01.016 |
1 |
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| 2012 |
Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marà F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/j.bcp.2011.11.006 |
1 |
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| 2012 |
Adams DJ, Callaghan B, Berecki G. Analgesic conotoxins: Block and G protein-coupled receptor modulation of N-type (Ca V2.2) calcium channels British Journal of Pharmacology. 166: 486-500. PMID 22091786 DOI: 10.1111/j.1476-5381.2011.01781.x |
1 |
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| 2011 |
Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA B receptor Journal of Medicinal Chemistry. 54: 6984-6992. PMID 21888386 DOI: 10.1021/jm201060r |
1 |
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| 2011 |
Azari H, Osborne GW, Yasuda T, Golmohammadi MG, Rahman M, Deleyrolle LP, Esfandiari E, Adams DJ, Scheffler B, Steindler DA, Reynolds BA. Purification of immature neuronal cells from neural stem cell progeny. Plos One. 6: e20941. PMID 21687800 DOI: 10.1371/journal.pone.0020941 |
1 |
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| 2011 |
de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/anie.201101642 |
1 |
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| 2011 |
Safavi-Hemami H, Siero WA, Kuang Z, Williamson NA, Karas JA, Page LR, MacMillan D, Callaghan B, Kompella SN, Adams DJ, Norton RS, Purcell AW. Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? The Journal of Biological Chemistry. 286: 22546-57. PMID 21504902 DOI: 10.1074/jbc.M110.217703 |
1 |
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| 2011 |
Daly NL, Callaghan B, Clark RJ, Nevin ST, Adams DJ, Craik DJ. Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237. PMID 21252227 DOI: 10.1074/jbc.M110.196170 |
1 |
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| 2011 |
Bongiorno D, Schuetz F, Poronnik P, Adams DJ. Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2 Channels. 5: 79-88. PMID 21057195 DOI: 10.4161/chan.5.1.13967 |
1 |
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| 2011 |
Klimis H, Adams DJ, Callaghan B, Nevin S, Alewood PF, Vaughan CW, Mozar CA, Christie MJ. A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152: 259-66. PMID 20889259 DOI: 10.1016/j.pain.2010.09.007 |
1 |
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| 2011 |
Lovelace ES, Gunasekera S, Alvarmo C, Clark RJ, Nevin ST, Grishin AA, Adams DJ, Craik DJ, Daly NL. Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization Antioxidants and Redox Signaling. 14: 87-95. PMID 20486767 DOI: 10.1089/ars.2009.3068 |
1 |
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| 2011 |
Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis J, Alewood PF, Christie MJ, Adams DJ. Analgesic ω-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels (Molecular Pharmacology (2010) 77, (139-148)) Molecular Pharmacology. 80: 356. DOI: 10.1124/mol.80.2.356 |
1 |
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| 2010 |
Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ, Craik DJ. The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548. PMID 20533477 DOI: 10.1002/anie.201000620 |
1 |
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| 2010 |
Yasuda T, Adams DJ. Physiological roles of ion channels in adult neural stem cells and their progeny. Journal of Neurochemistry. 114: 946-59. PMID 20492359 DOI: 10.1111/j.1471-4159.2010.06822.x |
1 |
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| 2010 |
Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 285: 22254-63. PMID 20466726 DOI: 10.1074/jbc.M110.111880 |
1 |
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| 2010 |
Callaghan B, Adams DJ. Analgesic alpha-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of alpha9 nicotinic receptor knockout mice Channels (Austin, Tex.). 4: 51-54. PMID 20368690 |
1 |
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| 2010 |
Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22. PMID 20163143 DOI: 10.1021/ja910602h |
1 |
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| 2010 |
Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ. Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels. Molecular Pharmacology. 77: 139-48. PMID 19892914 DOI: 10.1124/mol.109.058834 |
1 |
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| 2009 |
Halai R, Clark RJ, Nevin ST, Jensen JE, Adams DJ, Craik DJ. Scanning mutagenesis of α-conotoxin Vc1.1 reveals residues crucial for activity at the α9α10 nicotinic acetylcholine receptor Journal of Biological Chemistry. 284: 20275-20284. PMID 19447885 DOI: 10.1074/jbc.M109.015339 |
1 |
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| 2009 |
Whyte KA, Hogg RC, Dyavanapalli J, Harper AA, Adams DJ. Reactive oxygen species modulate neuronal excitability in rat intrinsic cardiac ganglia Autonomic Neuroscience: Basic and Clinical. 150: 45-52. PMID 19442588 DOI: 10.1016/j.autneu.2009.04.005 |
1 |
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| 2009 |
Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon. 54: 56-61. PMID 19306891 DOI: 10.1016/j.toxicon.2009.03.014 |
1 |
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| 2009 |
Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/jbc.M804950200 |
1 |
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| 2008 |
Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ. Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation Journal of Neuroscience. 28: 10943-10951. PMID 18945902 DOI: 10.1523/JNEUROSCI.3594-08.2008 |
1 |
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| 2008 |
Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84. PMID 18754612 DOI: 10.1021/jm800278k |
1 |
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| 2008 |
Motin L, Adams DJ. ω-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn Neuropharmacology. 55: 860-864. PMID 18644398 DOI: 10.1016/j.neuropharm.2008.06.049 |
1 |
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| 2008 |
Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. The Journal of Biological Chemistry. 283: 21621-8. PMID 18522941 DOI: 10.1074/jbc.M802852200 |
1 |
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| 2008 |
Schuetz F, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1 American Journal of Physiology - Cell Physiology. 295: C73-C80. PMID 18463232 DOI: 10.1152/ajpcell.00146.2008 |
1 |
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| 2008 |
Clark RJ, Daly NL, Halai R, Nevin ST, Adams DJ, Craik DJ. The three-dimensional structure of the analgesic α-conotoxin, RgIA Febs Letters. 582: 597-602. PMID 18242183 DOI: 10.1016/j.febslet.2008.01.027 |
1 |
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| 2008 |
Yasuda T, Bartlett PF, Adams DJ. K(ir) and K(v) channels regulate electrical properties and proliferation of adult neural precursor cells. Molecular and Cellular Neurosciences. 37: 284-97. PMID 18023363 DOI: 10.1016/j.mcn.2007.10.003 |
1 |
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| 2008 |
Ekberg J, Craik DJ, Adams DJ. Conotoxin modulation of voltage-gated sodium channels. The International Journal of Biochemistry & Cell Biology. 40: 2363-8. PMID 17951097 DOI: 10.1016/j.biocel.2007.08.017 |
1 |
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| 2007 |
Kloda A, Martinac B, Adams DJ. Polymodal regulation of NMDA receptor channels Channels. 1: 334-343. PMID 18690040 |
1 |
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| 2007 |
St Pierre L, Fischer H, Adams DJ, Schenning M, Lavidis N, De Jersey J, Masci PP, Lavin MF. Distinct activities of novel neurotoxins from Australian venomous snakes for nicotinic acetylcholine receptors Cellular and Molecular Life Sciences. 64: 2829-2840. PMID 17906946 DOI: 10.1007/s00018-007-7352-z |
1 |
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| 2007 |
Nevin ST, Clark RJ, Klimis H, Christie MJ, Craik DJ, Adams DJ. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins? Molecular Pharmacology. 72: 1406-10. PMID 17804600 DOI: 10.1124/mol.107.040568 |
1 |
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| 2007 |
Craik DJ, Adams DJ. Chemical modification of conotoxins to improve stability and activity Acs Chemical Biology. 2: 457-468. PMID 17649970 DOI: 10.1021/cb700091j |
1 |
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| 2007 |
Stafford MR, Bartlett PF, Adams DJ. Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone. Molecular and Cellular Neurosciences. 35: 535-48. PMID 17553694 DOI: 10.1016/j.mcn.2007.04.013 |
1 |
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| 2007 |
Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28 |
1 |
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| 2007 |
Walker TL, Yasuda T, Adams DJ, Bartlett PF. The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3734-42. PMID 17409237 DOI: 10.1523/JNEUROSCI.5060-06.2007 |
1 |
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| 2007 |
Dibbens LM, Ekberg J, Taylor I, Hodgson BL, Conroy SJ, Lensink IL, Kumar S, Zielinski MA, Harkin LA, Sutherland GR, Adams DJ, Berkovic SF, Scheffer IE, Mulley JC, Poronnik P. NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity. Genes, Brain, and Behavior. 6: 750-5. PMID 17331106 DOI: 10.1111/j.1601-183X.2007.00305.x |
1 |
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| 2007 |
Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. The Journal of Biological Chemistry. 282: 12135-42. PMID 17322297 DOI: 10.1074/jbc.M609385200 |
1 |
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| 2007 |
Motin L, Yasuda T, Schroeder CI, Lewis RJ, Adams DJ. Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels. The European Journal of Neuroscience. 25: 435-44. PMID 17284184 DOI: 10.1111/j.1460-9568.2006.05299.x |
1 |
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| 2007 |
Kloda A, Lua L, Hall R, Adams DJ, Martinac B. Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch Proceedings of the National Academy of Sciences of the United States of America. 104: 1540-1545. PMID 17242368 DOI: 10.1073/pnas.0609649104 |
1 |
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| 2007 |
Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Molecular Pharmacology. 71: 676-85. PMID 17142296 DOI: 10.1124/mol.106.028225 |
1 |
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| 2006 |
Ekberg J, Jayamanne A, Vaughan CW, Aslan S, Thomas L, Mould J, Drinkwater R, Baker MD, Abrahamsen B, Wood JN, Adams DJ, Christie MJ, Lewis RJ. muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits. Proceedings of the National Academy of Sciences of the United States of America. 103: 17030-5. PMID 17077153 DOI: 10.1073/pnas.0601819103 |
1 |
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| 2006 |
Ekberg J, Adams DJ. Neuronal voltage-gated sodium channel subtypes: key roles in inflammatory and neuropathic pain. The International Journal of Biochemistry & Cell Biology. 38: 2005-10. PMID 16919992 DOI: 10.1016/j.biocel.2006.06.008 |
1 |
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| 2006 |
Kloda A, Adams DJ. Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine British Journal of Pharmacology. 149: 163-169. PMID 16894346 DOI: 10.1038/sj.bjp.0706849 |
1 |
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| 2006 |
Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/jbc.M603703200 |
1 |
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| 2006 |
Clark RJ, Fischer H, Nevin ST, Adams DJ, Craik DJ. The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1 Journal of Biological Chemistry. 281: 23254-23263. PMID 16754662 DOI: 10.1074/jbc.M604550200 |
1 |
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| 2006 |
Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists Journal of Biological Chemistry. 281: 14136-14143. PMID 16500898 DOI: 10.1074/jbc.M512419200 |
1 |
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| 2006 |
Ragnarsson L, Yasuda T, Lewis RJ, Dodd PR, Adams DJ. NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G. Journal of Neurochemistry. 96: 283-91. PMID 16336218 DOI: 10.1111/j.1471-4159.2005.03574.x |
1 |
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| 2005 |
Clark RJ, Fischer H, Dempster L, Daly NL, Rosengren KJ, Nevin ST, Meunier FA, Adams DJ, Craik DJ. Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII Proceedings of the National Academy of Sciences of the United States of America. 102: 13767-13772. PMID 16162671 DOI: 10.1073/pnas.0504613102 |
1 |
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| 2005 |
Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner. The Journal of Pharmacology and Experimental Therapeutics. 314: 1353-61. PMID 15947038 DOI: 10.1124/jpet.105.085928 |
1 |
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| 2005 |
Fischer H, Liu DM, Lee A, Harries JC, Adams DJ. Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3571-7. PMID 15814787 DOI: 10.1523/JNEUROSCI.4971-04.2005 |
1 |
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| 2005 |
Fischer H, Harper AA, Anderson CR, Adams DJ. Developmental changes in expression of GABAA receptor-channels in rat intrinsic cardiac ganglion neurones. The Journal of Physiology. 564: 465-74. PMID 15731187 DOI: 10.1113/jphysiol.2005.084012 |
1 |
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| 2005 |
Kloda A, Adams DJ. Voltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine British Journal of Pharmacology. 144: 323-330. PMID 15655527 DOI: 10.1038/sj.bjp.0706049 |
1 |
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| 2005 |
Weber M, Motin L, Gaul S, Beker F, Fink RHA, Adams DJ. Intravenous anaesthetics inhibit nicotinic acetylcholine receptor-mediated currents and Ca 2+ transients in rat intracardiac ganglion neurons British Journal of Pharmacology. 144: 98-107. PMID 15644873 DOI: 10.1038/sj.bjp.0705942 |
1 |
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| 2004 |
Yasuda T, Chen L, Barr W, McRory JE, Lewis RJ, Adams DJ, Zamponi GW. Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells. The European Journal of Neuroscience. 20: 1-13. PMID 15245474 DOI: 10.1111/j.1460-9568.2004.03434.x |
1 |
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| 2004 |
Mould J, Yasuda T, Schroeder CI, Beedle AM, Doering CJ, Zamponi GW, Adams DJ, Lewis RJ. The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels. The Journal of Biological Chemistry. 279: 34705-14. PMID 15166237 DOI: 10.1074/jbc.M310848200 |
1 |
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| 2004 |
Kloda A, Clements JD, Lewis RJ, Adams DJ. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Molecular Pharmacology. 65: 1386-96. PMID 15155832 DOI: 10.1124/mol.65.6.1386 |
1 |
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| 2004 |
Adams DJ, Hill MA. Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells Journal of Cardiovascular Electrophysiology. 15: 598-610. PMID 15149433 |
1 |
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| 2004 |
Hogg RC, Chipperfield H, Whyte KA, Stafford MR, Hansen MA, Cool SM, Nurcombe V, Adams DJ. Functional maturation of isolated neural progenitor cells from the adult rat hippocampus. The European Journal of Neuroscience. 19: 2410-20. PMID 15128395 DOI: 10.1111/j.0953-816X.2004.03346.x |
1 |
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| 2004 |
Fotia AB, Ekberg J, Adams DJ, Cook DI, Poronnik P, Kumar S. Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. The Journal of Biological Chemistry. 279: 28930-5. PMID 15123669 DOI: 10.1074/jbc.M402820200 |
1 |
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| 2004 |
Daly NL, Ekberg JA, Thomas L, Adams DJ, Lewis RJ, Craik DJ. Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. The Journal of Biological Chemistry. 279: 25774-82. PMID 15044438 DOI: 10.1074/jbc.M313002200 |
1 |
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| 2004 |
Yasuda T, Lewis RJ, Adams DJ. Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation. The Journal of General Physiology. 123: 401-16. PMID 15024042 DOI: 10.1085/jgp.200308967 |
1 |
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| 2004 |
Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/jm031010o |
1 |
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| 2003 |
Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. The Journal of Biological Chemistry. 278: 40317-23. PMID 12885787 DOI: 10.1074/jbc.M213030200 |
1 |
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| 2003 |
Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of Biological Chemistry. 278: 34451-7. PMID 12824165 DOI: 10.1074/jbc.M305410200 |
1 |
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| 2003 |
Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/jbc.M212628200 |
1 |
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| 2003 |
Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. Journal of Medicinal Chemistry. 46: 1266-72. PMID 12646037 DOI: 10.1021/jm020426j |
1 |
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| 2003 |
Adams DJ, Smith AB, Schroeder CI, Yasuda T, Lewis RJ. Omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals. The Journal of Biological Chemistry. 278: 4057-62. PMID 12441339 DOI: 10.1074/jbc.M209969200 |
1 |
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| 2003 |
Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/jbc.M210280200 |
1 |
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| 2002 |
Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. The Journal of Biological Chemistry. 277: 48849-57. PMID 12376538 DOI: 10.1074/jbc.M208842200 |
1 |
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| 2002 |
Hogg RC, Lewis RJ, Adams DJ. Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons. The European Journal of Neuroscience. 16: 242-8. PMID 12169106 |
1 |
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| 2002 |
Adams DJ, Harper AA, Hogg RC. Neural control of the heart: developmental changes in ionic conductances in mammalian intrinsic cardiac neurons. Autonomic Neuroscience : Basic & Clinical. 98: 75-8. PMID 12144046 |
1 |
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| 2002 |
Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. The Journal of Biological Chemistry. 277: 27247-55. PMID 12006587 DOI: 10.1074/jbc.M201611200 |
1 |
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| 2001 |
Smith AB, Hansen MA, Liu DM, Adams DJ. Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia. Neuroscience. 107: 283-91. PMID 11731102 DOI: 10.1016/S0306-4522(01)00347-5 |
1 |
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| 2001 |
Sharpe IA, Gehrmann J, Loughnan ML, Thomas L, Adams DA, Atkins A, Palant E, Craik DJ, Adams DJ, Alewood PF, Lewis RJ. Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nature Neuroscience. 4: 902-7. PMID 11528421 DOI: 10.1038/nn0901-902 |
1 |
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| 2001 |
Hogg RC, Adams DJ. An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia. The Journal of Physiology. 534: 713-20. PMID 11483702 |
1 |
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| 2001 |
Liu DM, Adams DJ. Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia. The Journal of Physiology. 534: 423-35. PMID 11454961 DOI: 10.1111/j.1469-7793.2001.00423.x |
1 |
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| 2001 |
Hogg RC, Harper AA, Adams DJ. Developmental changes in hyperpolarization-activated currents I(h) and I(K(IR)) in isolated rat intracardiac neurons. Journal of Neurophysiology. 86: 312-20. PMID 11431512 |
1 |
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| 2000 |
Cuevas J, Adams DJ. Substance P preferentially inhibits large conductance nicotinic ACh receptor channels in rat intracardiac ganglion neurons. Journal of Neurophysiology. 84: 1961-70. PMID 11024089 |
1 |
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| 2000 |
Liu DM, Cuevas J, Adams DJ. VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation. The European Journal of Neuroscience. 12: 2243-51. PMID 10947803 DOI: 10.1046/j.1460-9568.2000.00116.x |
1 |
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| 2000 |
Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L, Jones A, Matheson JL, Drinkwater R, Andrews PR, Alewood PF. Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. The Journal of Biological Chemistry. 275: 35335-44. PMID 10938268 DOI: 10.1074/jbc.M002252200 |
1 |
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| 2000 |
Liu DM, Katnik C, Stafford M, Adams DJ. P2Y purinoceptor activation mobilizes intracellular Ca2+ and induces a membrane current in rat intracardiac neurones. The Journal of Physiology. 526: 287-98. PMID 10896718 |
1 |
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| 2000 |
Smith AB, Motin L, Lavidis NA, Adams DJ. Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia. Neuroscience. 95: 1121-7. PMID 10682719 |
1 |
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| 1999 |
Hogg RC, Miranda LP, Craik DJ, Lewis RJ, Alewood PF, Adams DJ. Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 274: 36559-64. PMID 10593955 |
1 |
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| 1999 |
Hogg RC, Trequattrini C, Catacuzzeno L, Petris A, Franciolini F, Adams DJ. Mechanisms of verapamil inhibition of action potential firing in rat intracardiac ganglion neurons. The Journal of Pharmacology and Experimental Therapeutics. 289: 1502-8. PMID 10336545 |
1 |
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| 1999 |
Smith AB, Adams DJ. Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones. Neuroscience Letters. 264: 105-8. PMID 10320025 |
1 |
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| 1998 |
Fransen P, Katnik C, Adams DJ. ACh- and caffeine-induced Ca2+ mobilization and current activation in rabbit arterial endothelial cells. The American Journal of Physiology. 275: H1748-58. PMID 9815082 |
1 |
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| 1998 |
Hogg RC, Lewis RJ, Adams DJ. Ciguatoxin (CTX-1) modulates single tetrodotoxin-sensitive sodium channels in rat parasympathetic neurones. Neuroscience Letters. 252: 103-6. PMID 9756332 |
1 |
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| 1998 |
Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, Livett BG, Down JG, Jones A, Alewood PF, Lewis RJ. alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 273: 15667-74. PMID 9624161 DOI: 10.1074/jbc.273.25.15667 |
1 |
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| 1998 |
Jeglitsch G, Rein K, Baden DG, Adams DJ. Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. The Journal of Pharmacology and Experimental Therapeutics. 284: 516-25. PMID 9454792 |
1 |
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| 1997 |
Cuevas J, Adams DJ. M4 muscarinic receptor activation modulates calcium channel currents in rat intracardiac neurons. Journal of Neurophysiology. 78: 1903-12. PMID 9325359 |
1 |
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| 1997 |
Cuevas J, Harper AA, Trequattrini C, Adams DJ. Passive and active membrane properties of isolated rat intracardiac neurons: regulation by H- and M-currents. Journal of Neurophysiology. 78: 1890-902. PMID 9325358 |
1 |
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| 1997 |
Katnik C, Adams DJ. Characterization of ATP-sensitive potassium channels in freshly dissociated rabbit aortic endothelial cells. The American Journal of Physiology. 272: H2507-11. PMID 9176323 |
1 |
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| 1997 |
Poth K, Nutter TJ, Cuevas J, Parker MJ, Adams DJ, Luetje CW. Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 586-96. PMID 8987781 |
1 |
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| 1996 |
Cuevas J, Adams DJ. Vasoactive intestinal polypeptide modulation of nicotinic ACh receptor channels in rat intracardiac neurones. The Journal of Physiology. 493: 503-15. PMID 8782112 |
1 |
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| 1995 |
Gawley RE, Rein KS, Jeglitsch G, Adams DJ, Theodorakis EA, Tiebes J, Nicolaou KC, Baden DG. The relationship of brevetoxin 'length' and A-ring functionality to binding and activity in neuronal sodium channels. Chemistry & Biology. 2: 533-41. PMID 9383457 DOI: 10.1016/1074-5521(95)90187-6 |
1 |
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| 1995 |
Rusko J, Van Slooten G, Adams DJ. Caffeine-evoked, calcium-sensitive membrane currents in rabbit aortic endothelial cells. British Journal of Pharmacology. 115: 133-41. PMID 7647967 |
1 |
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| 1995 |
Katnik C, Adams DJ. An ATP-sensitive potassium conductance in rabbit arterial endothelial cells. The Journal of Physiology. 485: 595-606. PMID 7562603 |
1 |
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| 1995 |
Nutter TJ, Adams DJ. Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia. The Journal of General Physiology. 105: 701-23. PMID 7561740 |
1 |
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| 1994 |
Laskey RE, Adams DJ, van Breemen C. Cytosolic [Ca2+] measurements in endothelium of rabbit cardiac valves using imaging fluorescence microscopy. The American Journal of Physiology. 266: H2130-5. PMID 8203612 |
1 |
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| 1994 |
Demirel E, Rusko J, Laskey RE, Adams DJ, van Breemen C. TEA inhibits ACh-induced EDRF release: endothelial Ca(2+)-dependent K+ channels contribute to vascular tone. The American Journal of Physiology. 267: H1135-41. PMID 8092278 |
1 |
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| 1994 |
Baden DG, Rein KS, Gawley RE, Jeglitsch G, Adams DJ. Is the A-ring lactone of brevetoxin PbTX-3 required for sodium channel orphan receptor binding and activity? Natural Toxins. 2: 212-221. PMID 7952946 DOI: 10.1002/nt.2620020410 |
1 |
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| 1994 |
Cuevas J, Adams DJ. Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. British Journal of Pharmacology. 111: 663-72. PMID 7517326 |
1 |
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| 1993 |
Xu ZJ, Adams DJ. Alpha-adrenergic modulation of ionic currents in cultured parasympathetic neurons from rat intracardiac ganglia. Journal of Neurophysiology. 69: 1060-70. PMID 8098358 |
1 |
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| 1992 |
Laskey RE, Adams DJ, Cannell M, van Breemen C. Calcium entry-dependent oscillations of cytoplasmic calcium concentration in cultured endothelial cell monolayers. Proceedings of the National Academy of Sciences of the United States of America. 89: 1690-4. PMID 1542661 |
1 |
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| 1992 |
Rusko J, Tanzi F, van Breemen C, Adams DJ. Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block. The Journal of Physiology. 455: 601-21. PMID 1484364 |
1 |
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| 1992 |
Xu ZJ, Adams DJ. Voltage-dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia. The Journal of Physiology. 456: 425-41. PMID 1338101 |
1 |
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| 1992 |
Adams DJ, Nutter TJ. Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons. Journal of Physiology, Paris. 86: 67-76. PMID 1285313 |
1 |
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| 1992 |
Xu ZJ, Adams DJ. Resting membrane potential and potassium currents in cultured parasympathetic neurones from rat intracardiac ganglia. The Journal of Physiology. 456: 405-24. PMID 1284080 |
1 |
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| 1991 |
Laskey RE, Adams DJ, Purkerson S, van Breemen C. Cytosolic calcium ion regulation in cultured endothelial cells. Advances in Experimental Medicine and Biology. 304: 257-71. PMID 1803902 |
1 |
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| 1991 |
Fieber LA, Adams DJ. Adenosine triphosphate-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. The Journal of Physiology. 434: 239-56. PMID 1708820 |
1 |
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| 1991 |
Fieber LA, Adams DJ. Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. The Journal of Physiology. 434: 215-37. PMID 1708819 |
1 |
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| 1990 |
Seabrook GR, Fieber LA, Adams DJ. Neurotransmission in neonatal rat cardiac ganglion in situ. The American Journal of Physiology. 259: H997-1005. PMID 2171366 |
1 |
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| 1990 |
Laskey RE, Adams DJ, Johns A, Rubanyi GM, van Breemen C. Membrane potential and Na(+)-K+ pump activity modulate resting and bradykinin-stimulated changes in cytosolic free calcium in cultured endothelial cells from bovine atria. The Journal of Biological Chemistry. 265: 2613-9. PMID 2154452 |
1 |
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| 1989 |
Seabrook GR, Adams DJ. Inhibition of neurally-evoked transmitter release by calcium channel antagonists in rat parasympathetic ganglia. British Journal of Pharmacology. 97: 1125-36. PMID 2571381 |
1 |
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| 1989 |
Adams DJ, Barakeh J, Laskey R, Van Breemen C. Ion channels and regulation of intracellular calcium in vascular endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 2389-400. PMID 2477294 |
1 |
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| 1988 |
Johns A, Freay AD, Adams DJ, Lategan TW, Ryan US, van Breemen C. Role of calcium in the activation of endothelial cells. Journal of Cardiovascular Pharmacology. 12: S119-23. PMID 2469868 |
1 |
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| 1987 |
Johns A, Lategan TW, Lodge NJ, Ryan US, Van Breemen C, Adams DJ. Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue & Cell. 19: 733-45. PMID 2449744 |
1 |
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| 1983 |
Adams DJ, Oxford GS. Interaction of internal anions with potassium channels of the squid giant axon. The Journal of General Physiology. 82: 429-48. PMID 6315855 |
1 |
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| 1982 |
Adams DJ, Gage PW, Hamill OP. Inhibitory postsynaptic currents at Aplysia cholinergic synapses: effects of permeant anions and depressant drugs. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 335-50. PMID 6127686 |
1 |
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| 1981 |
Adams DJ, Nonner W, Dwyer TM, Hille B. Block of endplate channels by permeant cations in frog skeletal muscle. The Journal of General Physiology. 78: 593-615. PMID 6278050 |
1 |
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| 1980 |
Adams DJ, Gage PW. Divalent ion currents and the delayed potassium conductance in an Aplysia neurone. The Journal of Physiology. 304: 297-313. PMID 6255142 |
1 |
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| 1980 |
Adams DJ, Dwyer TM, Hille B. The permeability of endplate channels to monovalent and divalent metal cations. The Journal of General Physiology. 75: 493-510. PMID 6247423 |
1 |
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| 1980 |
Dwyer TM, Adams DJ, Hille B. The permeability of the endplate channel to organic cations in frog muscle. The Journal of General Physiology. 75: 469-92. PMID 6247422 |
1 |
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| 1979 |
Adams DJ, Gage PW. Sodium and calcium gating currents in an Aplysia neurone. The Journal of Physiology. 291: 467-81. PMID 480239 |
1 |
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| 1979 |
Adams DJ, Gage PW. Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. The Journal of Physiology. 289: 143-61. PMID 458645 |
1 |
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| 1979 |
Adams DJ, Gage PW. Ionic currents in response to membrane depolarization in an Aplysia neurone. The Journal of Physiology. 289: 115-41. PMID 458642 |
1 |
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| 1977 |
Spence I, Adams DJ, Gage PW. Funnel web spider venom produces spontaneous action potentials in nerve. Life Sciences. 20: 243-49. PMID 839959 DOI: 10.1016/0024-3205(77)90318-6 |
1 |
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| 1977 |
Adams DJ, Gage PW, Hamill OP. Ethanol reduces excitatory postsynaptic current duration at a crustacean neuromuscular junction. Nature. 266: 739-41. PMID 195212 DOI: 10.1038/266739a0 |
1 |
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| 1976 |
Adams DJ, Gage PW. Gating currents associated with sodium and calcium currents in an Aplysia neuron. Science (New York, N.Y.). 192: 783-4. PMID 1265479 |
1 |
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| 1976 |
Adams DJ, Gage PW, Hamill OP. Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia. Brain Research. 115: 506-11. PMID 974759 DOI: 10.1016/0006-8993(76)90368-1 |
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