David J. Adams, PhD, UNSW - Publications

Affiliations: 
2015- Illawarra Health & Medical Research Institute University of Wollongong, Australia 
Area:
Membrane physiology, Ion channels, Receptor pharmacology, Conotoxins
Website:
https://scholars.uow.edu.au/display/david_adams

259 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wilhelm P, Luna-Ramirez K, Chin YK, Dekan Z, Abraham N, Tae HS, Chow CY, Eagles DA, King GF, Lewis RJ, Adams DJ, Alewood PF. Cysteine-Rich α-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor. Acs Chemical Neuroscience. PMID 35357806 DOI: 10.1021/acschemneuro.1c00857  0.815
2022 Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, ... ... Adams DJ, et al. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35074873 DOI: 10.1073/pnas.2110932119  0.81
2021 Yousuf A, Sadeghi M, Adams DJ. Venom-Derived Peptides Inhibiting Voltage-Gated Sodium and Calcium Channels in Mammalian Sensory Neurons. Advances in Experimental Medicine and Biology. 1349: 3-19. PMID 35138607 DOI: 10.1007/978-981-16-4254-8_1  0.829
2021 Yousuf A, Wu X, Bony AR, Sadeghi M, Huang YH, Craik DJ, Adams DJ. ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (Ca 2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABA receptor activation. Journal of Neurochemistry. PMID 34738241 DOI: 10.1111/jnc.15535  0.822
2021 Bony AR, McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via GABA receptor activation and reduce neuroexcitability. British Journal of Pharmacology. PMID 34599513 DOI: 10.1111/bph.15690  0.817
2021 Harper AA, Adams DJ. Electrical properties and synaptic transmission in mouse intracardiac ganglion neurons in situ. Physiological Reports. 9: e15056. PMID 34582125 DOI: 10.14814/phy2.15056  0.64
2021 Tae HS, Gao B, Jin AH, Alewood PF, Adams DJ. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors. Biochemical Pharmacology. 114638. PMID 34062129 DOI: 10.1016/j.bcp.2021.114638  0.764
2021 Ning H, Huang B, Tae HS, Liu Z, Yu S, Li L, Zhang L, Adams DJ, Guo C, Dai Q. α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and ɑ3β2 nicotinic acetylcholine receptor subtypes. Journal of Neurochemistry. PMID 34008858 DOI: 10.1111/jnc.15434  0.759
2021 Belgi A, Burnley JV, MacRaild CA, Chhabra S, Elnahriry KA, Robinson SD, Gooding SG, Tae HS, Bartels P, Sadeghi M, Zhao FY, Wei H, Spanswick D, Adams DJ, Norton RS, et al. Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models. Journal of Medicinal Chemistry. PMID 33724033 DOI: 10.1021/acs.jmedchem.0c02151  0.831
2021 Muttenthaler M, King GF, Adams DJ, Alewood PF. Trends in peptide drug discovery. Nature Reviews. Drug Discovery. PMID 33536635 DOI: 10.1038/s41573-020-00135-8  0.623
2020 McArthur JR, Munasinghe NR, Finol-Urdaneta RK, Adams DJ, Christie MJ. Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels. Frontiers in Pharmacology. 11: 633679. PMID 33584315 DOI: 10.3389/fphar.2020.633679  0.802
2020 Hulme AJ, McArthur JR, Maksour S, Miellet S, Ooi L, Adams DJ, Finol-Urdaneta RK, Dottori M. Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons. Frontiers in Cellular Neuroscience. 14: 600895. PMID 33362470 DOI: 10.3389/fncel.2020.600895  0.795
2020 Li X, Tae HS, Chu Y, Jiang T, Adams DJ, Yu R. Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor. Pharmacology & Therapeutics. 107792. PMID 33309557 DOI: 10.1016/j.pharmthera.2020.107792  0.829
2020 Arias HR, Ghelardini C, Lucarini E, Tae HS, Yousuf A, Marcovich I, Manetti D, Romanelli MN, Elgoyhen AB, Adams DJ, Di Cesare Mannelli L. ()-3-Furan-2-yl---tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation. Acs Chemical Neuroscience. PMID 33073974 DOI: 10.1021/acschemneuro.0c00476  0.824
2020 Ritter P, Bye LJ, Finol-Urdaneta RK, Lesko C, Adams DJ, Friedrich O, Gilbert DF. A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells. Experimental Cell Research. 112210. PMID 32750330 DOI: 10.1016/J.Yexcr.2020.112210  0.768
2020 Pooja D, Srinivasa Reddy T, Kulhari H, Kadari A, Adams DJ, Bansal V, Sistla R. N-acetyl-D-glucosamine-conjugated PAMAM Dendrimers as Dual Receptor-Targeting Nanocarriers for Anticancer Drug Delivery. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 32717387 DOI: 10.1016/J.Ejpb.2020.07.020  0.675
2020 Xu Q, Tae HS, Wang Z, Jiang T, Adams DJ, Yu R. Rational Design of α-Conotoxin RegIIA Analogues Specifically Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. Acs Chemical Neuroscience. PMID 32649832 DOI: 10.1021/Acschemneuro.0C00293  0.821
2020 Wen J, Adams DJ, Hung A. Interactions of the α3β2 Nicotinic Acetylcholine Receptor Interfaces with α-Conotoxin LsIA and its Carboxylated C-terminus Analogue: Molecular Dynamics Simulations. Marine Drugs. 18. PMID 32635340 DOI: 10.3390/Md18070349  0.621
2020 Arias HR, Tae HS, Micheli L, Yousuf A, Ghelardini C, Adams DJ, Di Cesare Mannelli L. Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and Ca2.2 channels. Neuropharmacology. 108194. PMID 32540451 DOI: 10.1016/J.Neuropharm.2020.108194  0.831
2020 Muttenthaler M, Nevin ST, Inserra M, Lewis RJ, Adams DJ, Alewood P. On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. Australian Journal of Chemistry. 73: 327-333. PMID 32394983 DOI: 10.1071/Ch19456  0.82
2020 Liang J, Tae HS, Xu X, Jiang T, Adams DJ, Yu R. Dimerization of α-conotoxins as a strategy to enhance the inhibition of the human α7 and α9α10 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. PMID 32101438 DOI: 10.1021/Acs.Jmedchem.9B01536  0.821
2020 Harper AA, Rimmer K, Dyavanapalli J, McArthur JR, Adams DJ. Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ. Neuropharmacology. 107932. PMID 31911104 DOI: 10.1016/J.Neuropharm.2019.107932  0.805
2020 Yap K, Du J, Looi FY, Tang SR, Veer SJd, Bony AR, Rehm FBH, Xie J, Chan LY, Wang CK, Adams DJ, Lua LHL, Durek T, Craik DJ. An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides Green Chemistry. 22: 5002-5016. DOI: 10.1039/D0Gc01366H  0.531
2020 Bony AR, McArthur JR, Finol-Urdaneta RK, Adams DJ. Modulation of Native and Recombinant GIRK1/2 Channels by Analgesic α-conotoxins Biophysical Journal. 118: 115a. DOI: 10.1016/J.Bpj.2019.11.772  0.82
2019 Chandna R, Tae HS, Seymour VAL, Chathrath S, Adams DJ, Kini RM. Drysdalin, an antagonist of nicotinic acetylcholine receptors highlights the importance of functional rather than structural conservation of amino acid residues. Faseb Bioadvances. 1: 115-131. PMID 32123825 DOI: 10.1096/fba.1027  0.765
2019 Luna-Ramirez K, Csoti A, McArthur JR, Chin YKY, Anangi R, Del Carmen Najera R, Possani LD, King GF, Panyi G, Yu H, Adams DJ, Finol-Urdaneta RK. Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochemical Pharmacology. 113782. PMID 31881193 DOI: 10.1016/J.Bcp.2019.113782  0.825
2019 Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic acetylcholine receptors. British Journal of Pharmacology. PMID 31877243 DOI: 10.1111/Bph.14954  0.811
2019 Chu X, Tae HS, Xu Q, Jiang T, Adams DJ, Yu R. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement. Acs Chemical Neuroscience. PMID 31411453 DOI: 10.1021/Acschemneuro.9B00389  0.801
2019 Pooja D, Gunukula A, Gupta N, Adams DJ, Kulhari H. Bombesin Receptors as Potential Targets for Anticancer Drug Delivery and Imaging. The International Journal of Biochemistry & Cell Biology. 105567. PMID 31295552 DOI: 10.1016/J.Biocel.2019.105567  0.668
2019 Kulhari H, Jangid AK, Adams DJ. Monoclonal Antibody-Conjugated Dendritic Nanostructures for siRNA Delivery. Methods in Molecular Biology (Clifton, N.J.). 1974: 195-201. PMID 31099004 DOI: 10.1007/978-1-4939-9220-1_14  0.642
2019 Yu R, Tae HS, Xu Q, Craik DJ, Adams DJ, Jiang T, Kaas Q. Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British Journal of Pharmacology. PMID 31062355 DOI: 10.1111/Bph.14698  0.809
2019 McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic TRPV1-active compounds inhibit native and recombinant T-type (Ca 3) calcium channels. British Journal of Pharmacology. PMID 30927254 DOI: 10.1111/Bph.14676  0.829
2019 Manolios N, Hou K, Tae H, Adams D. Ab0074 Interrelationship Between Nicotinic Acetylcholine Receptor And Cytokine Production Noted Following T-Cell Antigen Recognition And Activation Annals of the Rheumatic Diseases. 78: 1501-1501. DOI: 10.1136/Annrheumdis-2019-Eular.3856  0.38
2019 Dai Q, Liu Z, Ning H, Bartels P, Li L, Tang Y, Yu S, Sadeghi M, Zhang L, Du T, Huang B, Jiang L, Guo C, Adams DJ. Structures, functions of two novel α-conotoxins from conus snails in South China Sea Toxicon. 158: S26-S27. DOI: 10.1016/J.Toxicon.2018.10.096  0.779
2019 Xu S, Yang L, Kompella SN, Tae H, Zhang T, Lv A, Wang Y, Shao X, Ding J, Adams DJ, Wang C. Dissecting the nachr-inhibiting D-conotoxin GeXXA Toxicon. 158: S26. DOI: 10.1016/J.Toxicon.2018.10.095  0.783
2019 Yu R, Tae H, Tabassum N, Jiang T, Adams DJ. Interaction mechanism of α-conotoxins to the human α9α10 nAChR subtype Toxicon. 158: S24. DOI: 10.1016/J.Toxicon.2018.10.087  0.78
2018 Harvey PJ, Kurniawan ND, Finol-Urdaneta RK, McArthur JR, Van Lysebetten D, Dash TS, Hill JM, Adams DJ, Durek T, Craik DJ. NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced Na Channel Potency. Molecules (Basel, Switzerland). 23. PMID 30360356 DOI: 10.3390/Molecules23102715  0.823
2018 Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q. α-Conotoxin Vc1.1 Variants Target N-type Calcium Channels via GABA Receptor Activation and Display Improved Analgesic Activity. Journal of Medicinal Chemistry. PMID 30358401 DOI: 10.1021/Acs.Jmedchem.8B01343  0.753
2018 Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports. 8: 13397. PMID 30194442 DOI: 10.1038/S41598-018-31245-4  0.826
2018 Wu X, Tae HS, Huang YH, Adams DJ, Craik DJ, Kaas Q. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology. PMID 30009767 DOI: 10.1016/J.Bcp.2018.07.007  0.761
2018 Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/Acschembio.8B00190  0.857
2018 Yu R, Tae HS, Tabassum N, Shi J, Jiang T, Adams DJ. Molecular determinants conferring the stoichiometric-dependent activity of α-conotoxins at the human α9α10 nicotinic acetylcholine receptor subtype. Journal of Medicinal Chemistry. PMID 29733583 DOI: 10.1021/Acs.Jmedchem.8B00115  0.802
2018 Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Contribution of membrane receptor signalling to chronic visceral pain. The International Journal of Biochemistry & Cell Biology. PMID 29477359 DOI: 10.1016/J.Biocel.2018.02.017  0.762
2018 Liu Z, Bartels P, Sadeghi M, Du T, Dai Q, Zhu C, Yu S, Wang S, Dong M, Sun T, Guo J, Peng S, Jiang L, Adams DJ, Dai Q. A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity. Scientific Reports. 8: 1004. PMID 29343689 DOI: 10.1038/S41598-017-18479-4  0.851
2017 Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R. Role of Cys-Cys Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors. Acs Omega. 2: 4621-4631. PMID 30023726 DOI: 10.1021/acsomega.7b00639  0.779
2017 Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology. PMID 29194563 DOI: 10.1111/Bph.14115  0.77
2017 Durek T, Shelukhina IV, Tae HS, Thongyoo P, Spirova EN, Kudryavtsev DS, Kasheverov IE, Faure G, Corringer PJ, Craik DJ, Adams DJ, Tsetlin VI. Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports. 7: 16606. PMID 29192197 DOI: 10.1038/S41598-017-16809-0  0.772
2017 Adams DJ, Lewis RJ. Neuropharmacology of venom peptides. Neuropharmacology. PMID 29154773 DOI: 10.1016/J.Neuropharm.2017.11.025  0.437
2017 Hoggard MF, Rodriguez AM, Cano H, Clark E, Tae HS, Adams DJ, Godenschwege TA, Marí F. In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens. Neuropharmacology. PMID 28917942 DOI: 10.1016/J.Neuropharm.2017.09.020  0.781
2017 Wu X, Huang YH, Kaas Q, Harvey PJ, Wang CK, Tae HS, Adams DJ, Craik DJ. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. The Journal of Biological Chemistry. PMID 28851841 DOI: 10.1074/jbc.M117.808386  0.765
2017 Kulhari H, Telukutla SR, Pooja D, Shukla R, Sistla R, Bansal V, Adams DJ. Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma. Nanomedicine (London, England). PMID 28635550 DOI: 10.2217/Nnm-2017-0067  0.641
2017 McArthur JR, Motin L, Gleeson EC, Spiller S, Lewis RJ, Duggan PJ, Tuck KL, Adams DJ. Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1. British Journal of Pharmacology. PMID 28608537 DOI: 10.1111/Bph.13910  0.812
2017 Jiang S, Tae HS, Xu S, Shao X, Adams DJ, Wang C. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor. Marine Drugs. 15. PMID 28598389 DOI: 10.3390/Md15060170  0.753
2017 Yang L, Tae HS, Fan Z, Shao X, Xu S, Zhao S, Adams DJ, Wang C. A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA. Marine Drugs. 15. PMID 28587231 DOI: 10.3390/Md15060164  0.742
2017 Sadeghi M, McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons. Neuropharmacology. PMID 28533165 DOI: 10.1016/J.Neuropharm.2017.05.020  0.833
2017 Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ. α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. British Journal of Pharmacology. PMID 28477355 DOI: 10.1111/Bph.13852  0.826
2017 Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/S41598-017-01129-0  0.722
2016 Gilbert DF, Stebbing MJ, Kuenzel K, Murphy RM, Zacharewicz E, Buttgereit A, Stokes L, Adams DJ, Friedrich O. Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation. Frontiers in Molecular Neuroscience. 9: 111. PMID 27840602 DOI: 10.3389/Fnmol.2016.00111  0.581
2016 Pooja D, Kulhari H, Kuncha M, Rachamalla SS, Adams DJ, Bansal V, Sistla R. Improving efficacy, oral bioavailability and delivery of paclitaxel using protein-grafted solid lipid nanoparticles. Molecular Pharmaceutics. PMID 27696858 DOI: 10.1021/Acs.Molpharmaceut.6B00691  0.638
2016 Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. The Journal of Biological Chemistry. PMID 27646000 DOI: 10.1074/Jbc.M116.730804  0.802
2016 Berecki G, Motin L, Adams DJ. Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H. Neuropharmacology. PMID 27245500 DOI: 10.1016/J.Neuropharm.2016.05.019  0.798
2016 Pooja D, Kulhari H, Adams DJ, Sistla R. Formulation and dosage of therapeutic nanosuspension for active targeting of docetaxel (WO 2014210485A1). Expert Opinion On Therapeutic Patents. PMID 27088623 DOI: 10.1080/13543776.2016.1180365  0.64
2016 Kulhari H, Pooja D, Shrivastava S, Kuncha M, Naidu VG, Bansal V, Sistla R, Adams DJ. Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer. Scientific Reports. 6: 23179. PMID 27052896 DOI: 10.1038/Srep23179  0.633
2016 Carstens BB, Swedberg J, Berecki G, Adams DJ, Craik DJ, Clark RJ. Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers. PMID 27038328 DOI: 10.1002/Bip.22848  0.636
2016 Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/Anie.201600297  0.842
2016 Kulhari H, Pooja D, Kota R, Telukutla SR, Tabor RF, Shukla R, Adams DJ, Sistla R, Bansal V. Cyclic RGDfK Peptide Functionalized Polymeric Nanocarriers for Targeting Gemcitabine to Ovarian Cancer Cells. Molecular Pharmaceutics. PMID 26930230 DOI: 10.1021/Acs.Molpharmaceut.5B00935  0.648
2016 Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut. PMID 26887818 DOI: 10.1136/Gutjnl-2015-310971  0.678
2015 Motin L, Durek T, Adams DJ. Modulation of Human Nav1.7 Channel Gating by Synthetic α-Scorpion Toxin OD1 and its Analogues. Channels (Austin, Tex.). 0. PMID 26646206 DOI: 10.1080/19336950.2015.1120392  0.788
2015 Berecki G, Motin L, Adams DJ. R-type (Cav2.3) Calcium Channel Inhibition Via Human μ- δ- and κ-Opioid Receptors is Voltage-Independently Mediated by Gβγ Protein Subunits. Molecular Pharmacology. PMID 26490245 DOI: 10.1124/Mol.115.101154  0.796
2015 Hassan-Puttaswamy V, Adams DJ, Kini RM. A Distinct Functional Site in Ω-Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom. Acs Chemical Biology. PMID 26448325 DOI: 10.1021/Acschembio.5B00492  0.593
2015 Kompella SN, Cuny H, Hung A, Adams DJ. Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors. Molecular Pharmacology. 88: 993-1001. PMID 26438212 DOI: 10.1124/Mol.115.100503  0.834
2015 Xu S, Zhang T, Kompella SN, Yan M, Lu A, Wang Y, Shao X, Chi C, Adams DJ, Ding J, Wang C. Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Scientific Reports. 5: 14261. PMID 26395518 DOI: 10.1038/Srep14261  0.792
2015 Kulhari H, Pooja D, Singh MK, Kuncha M, Adams DJ, Sistla R. Bombesin-conjugated nanoparticles improve the cytotoxic efficacy of docetaxel against gastrin-releasing but androgen-independent prostate cancer. Nanomedicine (London, England). 10: 2847-59. PMID 26377157 DOI: 10.2217/Nnm.15.107  0.639
2015 Yu R, Seymour VA, Berecki G, Jia X, Akcan M, Adams DJ, Kaas Q, Craik DJ. Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports. 5: 13264. PMID 26290113 DOI: 10.1038/Srep13264  0.735
2015 Akcan M, Clark RJ, Daly NL, Conibear AC, de Faoite A, Heghinian MD, Sahil T, Adams DJ, Marí F, Craik DJ. Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins. Biopolymers. PMID 26172377 DOI: 10.1002/Bip.22699  0.728
2015 Kulhari H, Pooja D, Shrivastava S, Telukutala SR, Barui AK, Patra CR, Naidu VG, Adams DJ, Sistla R. Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 25933692 DOI: 10.1016/J.Nano.2015.04.007  0.667
2015 Kulhari H, Pooja D, Rompicharla SV, Sistla R, Adams DJ. Biomedical Applications of Trastuzumab: As a Therapeutic Agent and a Targeting Ligand. Medicinal Research Reviews. 35: 849-76. PMID 25847027 DOI: 10.1002/Med.21345  0.64
2015 Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/Jacs.5B00244  0.79
2015 Heghinian MD, Mejia M, Adams DJ, Godenschwege TA, Marí F. Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1011-8. PMID 25466886 DOI: 10.1096/Fj.14-262733  0.585
2015 Huynh TG, Cuny H, Slesinger PA, Adams DJ. Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor. Molecular Pharmacology. 87: 240-50. PMID 25425625 DOI: 10.1124/Mol.114.096156  0.817
2015 Kompella SN, Hung A, Clark RJ, Marí F, Adams DJ. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. The Journal of Biological Chemistry. 290: 1039-48. PMID 25411242 DOI: 10.1074/Jbc.M114.605592  0.829
2015 Berecki G, Motin L, Adams DJ. Inhibition of Human CaV2.3 Channels via μ-, δ- and κ-Opioid Receptor Activation Biophysical Journal. 108: 578a. DOI: 10.1016/J.Bpj.2014.11.3160  0.787
2014 Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. Journal of Medicinal Chemistry. 57: 9933-44. PMID 25393758 DOI: 10.1021/Jm501126U  0.849
2014 Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42. PMID 25101833 DOI: 10.1016/J.Bcp.2014.07.025  0.812
2014 Berecki G, McArthur JR, Cuny H, Clark RJ, Adams DJ. Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation. The Journal of General Physiology. 143: 465-79. PMID 24688019 DOI: 10.1085/Jgp.201311104  0.817
2014 Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology. 171: 3313-27. PMID 24628243 DOI: 10.1111/Bph.12686  0.622
2014 Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochemical Pharmacology. 89: 276-86. PMID 24561180 DOI: 10.1016/J.Bcp.2014.02.008  0.839
2014 Harrington AM, Castro J, Garcia-Caraballo S, Maddern J, Craik D, Adams DJ, Brierley SM. 888 α-Conotoxin Vc1.1 Targets GABAB Receptors Modulating CaV2.2 and CaV2.3 Calcium Channels in Sensory Pathways Mediating Chronic Visceral Pain Gastroenterology. 146: S-156. DOI: 10.1016/S0016-5085(14)60555-2  0.694
2013 Kabbani N, Nordman JC, Corgiat BA, Veltri DP, Shehu A, Seymour VA, Adams DJ. Are nicotinic acetylcholine receptors coupled to G proteins? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 1025-34. PMID 24185813 DOI: 10.1002/Bies.201300082  0.382
2013 Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/Jbc.M113.512582  0.831
2013 Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/J.Bcp.2013.07.016  0.814
2013 van Lierop BJ, Robinson SD, Kompella SN, Belgi A, McArthur JR, Hung A, MacRaild CA, Adams DJ, Norton RS, Robinson AJ. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chemical Biology. 8: 1815-21. PMID 23768016 DOI: 10.1021/Cb4002393  0.842
2013 Yu R, Kompella SN, Adams DJ, Craik DJ, Kaas Q. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry. 56: 3557-67. PMID 23566299 DOI: 10.1021/Jm400041H  0.798
2013 Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. Acs Chemical Biology. 8: 1215-22. PMID 23527544 DOI: 10.1021/Cb400012K  0.814
2013 Yasuda T, Cuny H, Adams DJ. Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation. The Journal of Physiology. 591: 2579-91. PMID 23478135 DOI: 10.1113/Jphysiol.2012.249151  0.814
2013 Adams DJ, Berecki G. Mechanisms of conotoxin inhibition of N-type (Ca(v)2.2) calcium channels. Biochimica Et Biophysica Acta. 1828: 1619-28. PMID 23380425 DOI: 10.1016/J.Bbamem.2013.01.019  0.434
2013 Adams DJ, Berecki G, Clark R, Craik DJ. Development of analgesic alpha-conotoxins for treatment of chronic pain Clinical and Experimental Pharmacology and Physiology. 40: 4-4. DOI: 10.1111/1440-1681.12170  0.615
2013 Kompella SN, Hung A, Clark RJ, Adams DJ. α-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency Biophysical Journal. 104: 634a. DOI: 10.1016/J.Bpj.2012.11.3505  0.837
2013 Kompella S, van Lierop B, Robinson S, Belgi A, Callaghan B, Hung A, MacRaild C, Norton R, Robinson A, Adams D. Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors Biochemical Pharmacology. 86: 1230. DOI: 10.1016/J.Bcp.2013.08.043  0.817
2013 Kompella S, Xu S, Zhang T, Yan M, Shao X, Chi C, Ding J, Wang C, Adams D. Novel strategy of blocking nAChR revealed by dissecting a dimeric conotoxin αD-GeXXA Biochemical Pharmacology. 86: 1229. DOI: 10.1016/J.Bcp.2013.08.041  0.773
2013 Adams D, Harper A, Grishin A, Cuny H. Actions of α-conotoxins on neuronal nicotinic acetylcholine receptors and synaptic transmission in rat parasympathetic ganglia Autonomic Neuroscience. 177: 306. DOI: 10.1016/J.Autneu.2013.08.027  0.808
2012 Knapp O, McArthur JR, Adams DJ. Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics? Toxins. 4: 1236-60. PMID 23202314 DOI: 10.3390/Toxins4111236  0.822
2012 Rupasinghe DB, Knapp O, Blomster LV, Schmid AB, Adams DJ, King GF, Ruitenberg MJ. Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function. Channels (Austin, Tex.). 6: 103-10. PMID 22622154 DOI: 10.4161/Chan.19484  0.779
2012 Cuny H, de Faoite A, Huynh TG, Yasuda T, Berecki G, Adams DJ. γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxins. The Journal of Biological Chemistry. 287: 23948-57. PMID 22613715 DOI: 10.1074/Jbc.M112.342998  0.826
2012 Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochemical Pharmacology. 84: 540-8. PMID 22609441 DOI: 10.1016/J.Bcp.2012.05.008  0.807
2012 Knapp O, Nevin ST, Yasuda T, Lawrence N, Lewis RJ, Adams DJ. Biophysical properties of Na(v) 1.8/Na(v) 1.2 chimeras and inhibition by µO-conotoxin MrVIB. British Journal of Pharmacology. 166: 2148-60. PMID 22452751 DOI: 10.1111/J.1476-5381.2012.01955.X  0.801
2012 Napier IA, Klimis H, Rycroft BK, Jin AH, Alewood PF, Motin L, Adams DJ, Christie MJ. Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain. Neuropharmacology. 62: 2202-7. PMID 22306793 DOI: 10.1016/J.Neuropharm.2012.01.016  0.823
2012 Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marí F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/J.Bcp.2011.11.006  0.828
2012 Adams DJ, Callaghan B, Berecki G. Analgesic conotoxins: Block and G protein-coupled receptor modulation of N-type (Ca V2.2) calcium channels British Journal of Pharmacology. 166: 486-500. PMID 22091786 DOI: 10.1111/J.1476-5381.2011.01781.X  0.682
2012 Franco A, Heighinian M, Mejia M, McCall J, Nag S, Akondi K, Melaun C, Daly N, Luetje CW, Alewood PF, Craik DJ, Godenschwege T, Adams DJ, Marí F. 105. Discovery, Characterization, and Functional Implications of Conotoxins from Cone Snails Species of the Americas Toxicon. 60: 148. DOI: 10.1016/J.Toxicon.2012.04.106  0.663
2012 Klint J, Anangi R, Mobli M, Knapp O, Adams DJ, King GF. 31. Spider-venom Peptides that Target the Human NaV1.7 channel: Potential Analgesics for the Treatment of Chronic Pain Toxicon. 60: 110-111. DOI: 10.1016/J.Toxicon.2012.04.032  0.8
2012 Huynh TG, Berecki G, Adams DJ. Modulation of Cav2.2 Channels via Activation of Human GABAB Receptors Expressed in HEK293 Cells by Analgesic α-Conotoxins Biophysical Journal. 102: 135a. DOI: 10.1016/J.Bpj.2011.11.748  0.466
2011 Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA B receptor Journal of Medicinal Chemistry. 54: 6984-6992. PMID 21888386 DOI: 10.1021/Jm201060R  0.755
2011 Azari H, Osborne GW, Yasuda T, Golmohammadi MG, Rahman M, Deleyrolle LP, Esfandiari E, Adams DJ, Scheffler B, Steindler DA, Reynolds BA. Purification of immature neuronal cells from neural stem cell progeny. Plos One. 6: e20941. PMID 21687800 DOI: 10.1371/Journal.Pone.0020941  0.631
2011 de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/Anie.201101642  0.783
2011 Safavi-Hemami H, Siero WA, Kuang Z, Williamson NA, Karas JA, Page LR, MacMillan D, Callaghan B, Kompella SN, Adams DJ, Norton RS, Purcell AW. Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? The Journal of Biological Chemistry. 286: 22546-57. PMID 21504902 DOI: 10.1074/Jbc.M110.217703  0.802
2011 Daly NL, Callaghan B, Clark RJ, Nevin ST, Adams DJ, Craik DJ. Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237. PMID 21252227 DOI: 10.1074/Jbc.M110.196170  0.843
2011 Bongiorno D, Schuetz F, Poronnik P, Adams DJ. Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2 Channels. 5: 79-88. PMID 21057195 DOI: 10.4161/Chan.5.1.13967  0.695
2011 Klimis H, Adams DJ, Callaghan B, Nevin S, Alewood PF, Vaughan CW, Mozar CA, Christie MJ. A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152: 259-66. PMID 20889259 DOI: 10.1016/J.Pain.2010.09.007  0.847
2011 Lovelace ES, Gunasekera S, Alvarmo C, Clark RJ, Nevin ST, Grishin AA, Adams DJ, Craik DJ, Daly NL. Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization Antioxidants and Redox Signaling. 14: 87-95. PMID 20486767 DOI: 10.1089/Ars.2009.3068  0.816
2011 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis J, Alewood PF, Christie MJ, Adams DJ. Analgesic ω-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels (Molecular Pharmacology (2010) 77, (139-148)) Molecular Pharmacology. 80: 356. DOI: 10.1124/Mol.80.2.356  0.811
2011 Adams D, Grishin A, Hung A, Clark R, Akondi K, Alewood P, Craik D. Scanning mutagenesis of α-conotoxin AuIB reveals a critical residue for activity at the α3β4 nicotinic acetylcholine receptor Biochemical Pharmacology. 82: 1028. DOI: 10.1016/J.Bcp.2011.07.017  0.817
2010 Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ, Craik DJ. The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548. PMID 20533477 DOI: 10.1002/Anie.201000620  0.792
2010 Yasuda T, Adams DJ. Physiological roles of ion channels in adult neural stem cells and their progeny. Journal of Neurochemistry. 114: 946-59. PMID 20492359 DOI: 10.1111/J.1471-4159.2010.06822.X  0.664
2010 Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 285: 22254-63. PMID 20466726 DOI: 10.1074/Jbc.M110.111880  0.822
2010 Callaghan B, Adams DJ. Analgesic alpha-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of alpha9 nicotinic receptor knockout mice Channels (Austin, Tex.). 4: 51-54. PMID 20368690 DOI: 10.4161/Chan.4.1.10281  0.663
2010 Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22. PMID 20163143 DOI: 10.1021/Ja910602H  0.801
2010 Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ. Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels. Molecular Pharmacology. 77: 139-48. PMID 19892914 DOI: 10.1124/Mol.109.058834  0.837
2010 Clark R, Guille V, Callaghan B, Adams D, Craik D. 167 DEVELOPMENT OF AN ORALLY ACTIVE PEPTIDE FOR THE TREATMENT OF NEUROPATHIC PAIN European Journal of Pain Supplements. 4: 50-50. DOI: 10.1016/S1754-3207(10)70172-3  0.714
2010 Clark R, Jensen J, Nevin S, Callaghan B, Adams D, Craik D. Inside Cover: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. Int. Ed. 37/2010) Angewandte Chemie International Edition. 49: 6460-6460. DOI: 10.1002/Anie.201003933  0.769
2010 Clark R, Jensen J, Nevin S, Callaghan B, Adams D, Craik D. Innentitelbild: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. 37/2010) Angewandte Chemie. 122: 6606-6606. DOI: 10.1002/Ange.201003933  0.768
2009 Halai R, Clark RJ, Nevin ST, Jensen JE, Adams DJ, Craik DJ. Scanning mutagenesis of α-conotoxin Vc1.1 reveals residues crucial for activity at the α9α10 nicotinic acetylcholine receptor Journal of Biological Chemistry. 284: 20275-20284. PMID 19447885 DOI: 10.1074/Jbc.M109.015339  0.829
2009 Whyte KA, Hogg RC, Dyavanapalli J, Harper AA, Adams DJ. Reactive oxygen species modulate neuronal excitability in rat intrinsic cardiac ganglia Autonomic Neuroscience: Basic and Clinical. 150: 45-52. PMID 19442588 DOI: 10.1016/J.Autneu.2009.04.005  0.635
2009 Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon. 54: 56-61. PMID 19306891 DOI: 10.1016/J.Toxicon.2009.03.014  0.674
2009 Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/Jbc.M804950200  0.823
2009 Halai R, Clark R, Nevin S, Adams D, Craik D. Mutational atudies on alpha-conotoxin VCL1 Biopolymers. 92: 315-315. DOI: 10.1002/Bip.21223  0.767
2008 Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ. Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation Journal of Neuroscience. 28: 10943-10951. PMID 18945902 DOI: 10.1523/Jneurosci.3594-08.2008  0.853
2008 Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84. PMID 18754612 DOI: 10.1021/Jm800278K  0.802
2008 Motin L, Adams DJ. ω-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn Neuropharmacology. 55: 860-864. PMID 18644398 DOI: 10.1016/J.Neuropharm.2008.06.049  0.762
2008 Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. The Journal of Biological Chemistry. 283: 21621-8. PMID 18522941 DOI: 10.1074/Jbc.M802852200  0.736
2008 Schuetz F, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1 American Journal of Physiology - Cell Physiology. 295: C73-C80. PMID 18463232 DOI: 10.1152/Ajpcell.00146.2008  0.696
2008 Clark RJ, Daly NL, Halai R, Nevin ST, Adams DJ, Craik DJ. The three-dimensional structure of the analgesic α-conotoxin, RgIA Febs Letters. 582: 597-602. PMID 18242183 DOI: 10.1016/J.Febslet.2008.01.027  0.815
2008 Yasuda T, Bartlett PF, Adams DJ. K(ir) and K(v) channels regulate electrical properties and proliferation of adult neural precursor cells. Molecular and Cellular Neurosciences. 37: 284-97. PMID 18023363 DOI: 10.1016/J.Mcn.2007.10.003  0.724
2008 Ekberg J, Craik DJ, Adams DJ. Conotoxin modulation of voltage-gated sodium channels. The International Journal of Biochemistry & Cell Biology. 40: 2363-8. PMID 17951097 DOI: 10.1016/J.Biocel.2007.08.017  0.697
2007 Kloda A, Martinac B, Adams DJ. Polymodal regulation of NMDA receptor channels Channels. 1: 334-343. PMID 18690040 DOI: 10.4161/Chan.5044  0.803
2007 St Pierre L, Fischer H, Adams DJ, Schenning M, Lavidis N, De Jersey J, Masci PP, Lavin MF. Distinct activities of novel neurotoxins from Australian venomous snakes for nicotinic acetylcholine receptors Cellular and Molecular Life Sciences. 64: 2829-2840. PMID 17906946 DOI: 10.1007/S00018-007-7352-Z  0.736
2007 Nevin ST, Clark RJ, Klimis H, Christie MJ, Craik DJ, Adams DJ. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins? Molecular Pharmacology. 72: 1406-10. PMID 17804600 DOI: 10.1124/Mol.107.040568  0.826
2007 Craik DJ, Adams DJ. Chemical modification of conotoxins to improve stability and activity Acs Chemical Biology. 2: 457-468. PMID 17649970 DOI: 10.1021/Cb700091J  0.506
2007 Stafford MR, Bartlett PF, Adams DJ. Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone. Molecular and Cellular Neurosciences. 35: 535-48. PMID 17553694 DOI: 10.1016/J.Mcn.2007.04.013  0.719
2007 Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28  0.798
2007 Walker TL, Yasuda T, Adams DJ, Bartlett PF. The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3734-42. PMID 17409237 DOI: 10.1523/Jneurosci.5060-06.2007  0.706
2007 Dibbens LM, Ekberg J, Taylor I, Hodgson BL, Conroy SJ, Lensink IL, Kumar S, Zielinski MA, Harkin LA, Sutherland GR, Adams DJ, Berkovic SF, Scheffer IE, Mulley JC, Poronnik P. NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity. Genes, Brain, and Behavior. 6: 750-5. PMID 17331106 DOI: 10.1111/J.1601-183X.2007.00305.X  0.572
2007 Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. The Journal of Biological Chemistry. 282: 12135-42. PMID 17322297 DOI: 10.1074/Jbc.M609385200  0.769
2007 Motin L, Yasuda T, Schroeder CI, Lewis RJ, Adams DJ. Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels. The European Journal of Neuroscience. 25: 435-44. PMID 17284184 DOI: 10.1111/J.1460-9568.2006.05299.X  0.821
2007 Kloda A, Lua L, Hall R, Adams DJ, Martinac B. Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch Proceedings of the National Academy of Sciences of the United States of America. 104: 1540-1545. PMID 17242368 DOI: 10.1073/Pnas.0609649104  0.802
2007 Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Molecular Pharmacology. 71: 676-85. PMID 17142296 DOI: 10.1124/Mol.106.028225  0.748
2006 Ekberg J, Jayamanne A, Vaughan CW, Aslan S, Thomas L, Mould J, Drinkwater R, Baker MD, Abrahamsen B, Wood JN, Adams DJ, Christie MJ, Lewis RJ. muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits. Proceedings of the National Academy of Sciences of the United States of America. 103: 17030-5. PMID 17077153 DOI: 10.1073/Pnas.0601819103  0.808
2006 Ekberg J, Adams DJ. Neuronal voltage-gated sodium channel subtypes: key roles in inflammatory and neuropathic pain. The International Journal of Biochemistry & Cell Biology. 38: 2005-10. PMID 16919992 DOI: 10.1016/J.Biocel.2006.06.008  0.594
2006 Kloda A, Adams DJ. Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine British Journal of Pharmacology. 149: 163-169. PMID 16894346 DOI: 10.1038/Sj.Bjp.0706849  0.759
2006 Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/Jbc.M603703200  0.833
2006 Clark RJ, Fischer H, Nevin ST, Adams DJ, Craik DJ. The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1 Journal of Biological Chemistry. 281: 23254-23263. PMID 16754662 DOI: 10.1074/Jbc.M604550200  0.83
2006 Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists Journal of Biological Chemistry. 281: 14136-14143. PMID 16500898 DOI: 10.1074/Jbc.M512419200  0.804
2006 Ragnarsson L, Yasuda T, Lewis RJ, Dodd PR, Adams DJ. NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G. Journal of Neurochemistry. 96: 283-91. PMID 16336218 DOI: 10.1111/J.1471-4159.2005.03574.X  0.699
2005 Clark RJ, Fischer H, Dempster L, Daly NL, Rosengren KJ, Nevin ST, Meunier FA, Adams DJ, Craik DJ. Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII Proceedings of the National Academy of Sciences of the United States of America. 102: 13767-13772. PMID 16162671 DOI: 10.1073/Pnas.0504613102  0.81
2005 Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner. The Journal of Pharmacology and Experimental Therapeutics. 314: 1353-61. PMID 15947038 DOI: 10.1124/Jpet.105.085928  0.421
2005 Fischer H, Liu DM, Lee A, Harries JC, Adams DJ. Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3571-7. PMID 15814787 DOI: 10.1523/Jneurosci.4971-04.2005  0.786
2005 Fischer H, Harper AA, Anderson CR, Adams DJ. Developmental changes in expression of GABAA receptor-channels in rat intrinsic cardiac ganglion neurones. The Journal of Physiology. 564: 465-74. PMID 15731187 DOI: 10.1113/Jphysiol.2005.084012  0.786
2005 Kloda A, Adams DJ. Voltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine British Journal of Pharmacology. 144: 323-330. PMID 15655527 DOI: 10.1038/Sj.Bjp.0706049  0.744
2005 Weber M, Motin L, Gaul S, Beker F, Fink RHA, Adams DJ. Intravenous anaesthetics inhibit nicotinic acetylcholine receptor-mediated currents and Ca 2+ transients in rat intracardiac ganglion neurons British Journal of Pharmacology. 144: 98-107. PMID 15644873 DOI: 10.1038/Sj.Bjp.0705942  0.787
2004 Yasuda T, Chen L, Barr W, McRory JE, Lewis RJ, Adams DJ, Zamponi GW. Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells. The European Journal of Neuroscience. 20: 1-13. PMID 15245474 DOI: 10.1111/J.1460-9568.2004.03434.X  0.781
2004 Mould J, Yasuda T, Schroeder CI, Beedle AM, Doering CJ, Zamponi GW, Adams DJ, Lewis RJ. The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels. The Journal of Biological Chemistry. 279: 34705-14. PMID 15166237 DOI: 10.1074/Jbc.M310848200  0.822
2004 Kloda A, Clements JD, Lewis RJ, Adams DJ. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Molecular Pharmacology. 65: 1386-96. PMID 15155832 DOI: 10.1124/Mol.65.6.1386  0.775
2004 Adams DJ, Hill MA. Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells Journal of Cardiovascular Electrophysiology. 15: 598-610. PMID 15149433 DOI: 10.1046/J.1540-8167.2004.03277.X  0.347
2004 Hogg RC, Chipperfield H, Whyte KA, Stafford MR, Hansen MA, Cool SM, Nurcombe V, Adams DJ. Functional maturation of isolated neural progenitor cells from the adult rat hippocampus. The European Journal of Neuroscience. 19: 2410-20. PMID 15128395 DOI: 10.1111/J.0953-816X.2004.03346.X  0.821
2004 Fotia AB, Ekberg J, Adams DJ, Cook DI, Poronnik P, Kumar S. Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. The Journal of Biological Chemistry. 279: 28930-5. PMID 15123669 DOI: 10.1074/Jbc.M402820200  0.589
2004 Daly NL, Ekberg JA, Thomas L, Adams DJ, Lewis RJ, Craik DJ. Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. The Journal of Biological Chemistry. 279: 25774-82. PMID 15044438 DOI: 10.1074/Jbc.M313002200  0.734
2004 Yasuda T, Lewis RJ, Adams DJ. Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation. The Journal of General Physiology. 123: 401-16. PMID 15024042 DOI: 10.1085/Jgp.200308967  0.715
2004 Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/Jm031010O  0.757
2004 Ragnarsson LK, Yasuda T, Adams DJ, Lewis RJ, Dodd PR. NMDA receptor variant responses to conantokins Journal of Neurochemistry. 88: 67-67. DOI: 10.1046/J.1474-1644.2003.2314P26_01.X  0.707
2003 Moccia F, Frost C, Berra-Romani R, Tanzi F, Adams DJ. Expression and function of neuronal nicotinic ACh receptors in rat microvascular endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 286: H486-91. PMID 14512281 DOI: 10.1152/Ajpheart.00620.2003  0.422
2003 Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. The Journal of Biological Chemistry. 278: 40317-23. PMID 12885787 DOI: 10.1074/Jbc.M213030200  0.8
2003 Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of Biological Chemistry. 278: 34451-7. PMID 12824165 DOI: 10.1074/Jbc.M305410200  0.803
2003 Beker F, Weber M, Fink RH, Adams DJ. Muscarinic and nicotinic ACh receptor activation differentially mobilize Ca2+ in rat intracardiac ganglion neurons. Journal of Neurophysiology. 90: 1956-64. PMID 12761283 DOI: 10.1152/Jn.01079.2002  0.366
2003 Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/Jbc.M212628200  0.549
2003 Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. Journal of Medicinal Chemistry. 46: 1266-72. PMID 12646037 DOI: 10.1021/Jm020426J  0.813
2003 Adams DJ, Smith AB, Schroeder CI, Yasuda T, Lewis RJ. Omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals. The Journal of Biological Chemistry. 278: 4057-62. PMID 12441339 DOI: 10.1074/Jbc.M209969200  0.8
2003 Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/Jbc.M210280200  0.761
2002 Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. The Journal of Biological Chemistry. 277: 48849-57. PMID 12376538 DOI: 10.1074/Jbc.M208842200  0.627
2002 Moccia F, Berra-Romani R, Baruffi S, Spaggiari S, Adams DJ, Taglietti V, Tanzi F. Basal nonselective cation permeability in rat cardiac microvascular endothelial cells. Microvascular Research. 64: 187-197. PMID 12204642 DOI: 10.1006/Mvre.2002.2430  0.32
2002 Hogg RC, Lewis RJ, Adams DJ. Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons. The European Journal of Neuroscience. 16: 242-8. PMID 12169106 DOI: 10.1046/J.1460-9568.2002.02071.X  0.478
2002 Adams DJ, Harper AA, Hogg RC. Neural control of the heart: developmental changes in ionic conductances in mammalian intrinsic cardiac neurons. Autonomic Neuroscience : Basic & Clinical. 98: 75-8. PMID 12144046 DOI: 10.1016/S1566-0702(02)00036-X  0.661
2002 Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. The Journal of Biological Chemistry. 277: 27247-55. PMID 12006587 DOI: 10.1074/Jbc.M201611200  0.806
2001 Smith AB, Hansen MA, Liu DM, Adams DJ. Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia. Neuroscience. 107: 283-91. PMID 11731102 DOI: 10.1016/S0306-4522(01)00347-5  0.706
2001 Sharpe IA, Gehrmann J, Loughnan ML, Thomas L, Adams DA, Atkins A, Palant E, Craik DJ, Adams DJ, Alewood PF, Lewis RJ. Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nature Neuroscience. 4: 902-7. PMID 11528421 DOI: 10.1038/Nn0901-902  0.802
2001 Hogg RC, Adams DJ. An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia. The Journal of Physiology. 534: 713-20. PMID 11483702 DOI: 10.1111/J.1469-7793.2001.00713.X  0.364
2001 Liu DM, Adams DJ. Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia. The Journal of Physiology. 534: 423-35. PMID 11454961 DOI: 10.1111/J.1469-7793.2001.00423.X  0.581
2001 Hogg RC, Harper AA, Adams DJ. Developmental changes in hyperpolarization-activated currents I(h) and I(K(IR)) in isolated rat intracardiac neurons. Journal of Neurophysiology. 86: 312-20. PMID 11431512 DOI: 10.1152/Jn.2001.86.1.312  0.626
2001 Franciolini F, Hogg R, Catacuzzeno L, Petris A, Trequattrini C, Adams DJ. Large-conductance calcium-activated potassium channels in neonatal rat intracardiac ganglion neurons. Pflugers Archiv : European Journal of Physiology. 441: 629-38. PMID 11294244 DOI: 10.1007/S004240000471  0.416
2001 Blanchfield J, Dutton J, Hogg R, Craik D, Adams D, Lewis R, Alewood P, Toth I. The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII Letters in Peptide Science. 8: 235-239. DOI: 10.1023/A:1016577832311  0.687
2001 Blanchfield J, Dutton J, Hogg R, Craik D, Adams D, Lewis R, Alewood P, Toth I. Letters in Peptide Science. 8: 235-239. DOI: 10.1023/A:1016577832311  0.415
2000 Cuevas J, Adams DJ. Substance P preferentially inhibits large conductance nicotinic ACh receptor channels in rat intracardiac ganglion neurons. Journal of Neurophysiology. 84: 1961-70. PMID 11024089 DOI: 10.1152/Jn.2000.84.4.1961  0.636
2000 Liu DM, Cuevas J, Adams DJ. VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation. The European Journal of Neuroscience. 12: 2243-51. PMID 10947803 DOI: 10.1046/J.1460-9568.2000.00116.X  0.71
2000 Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L, Jones A, Matheson JL, Drinkwater R, Andrews PR, Alewood PF. Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. The Journal of Biological Chemistry. 275: 35335-44. PMID 10938268 DOI: 10.1074/Jbc.M002252200  0.812
2000 Liu DM, Katnik C, Stafford M, Adams DJ. P2Y purinoceptor activation mobilizes intracellular Ca2+ and induces a membrane current in rat intracardiac neurones. The Journal of Physiology. 526: 287-98. PMID 10896718 DOI: 10.1111/J.1469-7793.2000.00287.X  0.796
2000 Smith AB, Motin L, Lavidis NA, Adams DJ. Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia. Neuroscience. 95: 1121-7. PMID 10682719 DOI: 10.1016/S0306-4522(99)00505-9  0.811
1999 Hogg RC, Miranda LP, Craik DJ, Lewis RJ, Alewood PF, Adams DJ. Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 274: 36559-64. PMID 10593955 DOI: 10.1074/Jbc.274.51.36559  0.702
1999 Nielsen KJ, Adams D, Thomas L, Bond T, Alewood PF, Craik DJ, Lewis RJ. Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels. Journal of Molecular Biology. 289: 1405-21. PMID 10373375 DOI: 10.1006/Jmbi.1999.2817  0.665
1999 Smith AB, Adams DJ. Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones. Neuroscience Letters. 264: 105-8. PMID 10320025 DOI: 10.1016/S0304-3940(99)00180-9  0.644
1999 Adams DJ, Alewood PF, Craik DJ, Drinkwater RD, Lewis RJ. Conotoxins and their potential pharmaceutical applications Drug Development Research. 46: 219-234. DOI: 10.1002/(Sici)1098-2299(199903/04)46:3/4<219::Aid-Ddr7>3.0.Co;2-S  0.684
1998 Fransen P, Katnik C, Adams DJ. ACh- and caffeine-induced Ca2+ mobilization and current activation in rabbit arterial endothelial cells. The American Journal of Physiology. 275: H1748-58. PMID 9815082 DOI: 10.1152/Ajpheart.1998.275.5.H1748  0.753
1998 Hogg RC, Lewis RJ, Adams DJ. Ciguatoxin (CTX-1) modulates single tetrodotoxin-sensitive sodium channels in rat parasympathetic neurones. Neuroscience Letters. 252: 103-6. PMID 9756332 DOI: 10.1016/S0304-3940(98)00575-8  0.538
1998 Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, Livett BG, Down JG, Jones A, Alewood PF, Lewis RJ. alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 273: 15667-74. PMID 9624161 DOI: 10.1074/Jbc.273.25.15667  0.744
1998 Adams DJ, Trequattrini C. Opioid receptor-mediated inhibition of ω-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons Journal of Neurophysiology. 79: 753-762. PMID 9463438 DOI: 10.1152/Jn.1998.79.2.753  0.389
1998 Jeglitsch G, Rein K, Baden DG, Adams DJ. Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. The Journal of Pharmacology and Experimental Therapeutics. 284: 516-25. PMID 9454792  0.825
1997 Cuevas J, Adams DJ. M4 muscarinic receptor activation modulates calcium channel currents in rat intracardiac neurons. Journal of Neurophysiology. 78: 1903-12. PMID 9325359 DOI: 10.1152/Jn.1997.78.4.1903  0.655
1997 Cuevas J, Harper AA, Trequattrini C, Adams DJ. Passive and active membrane properties of isolated rat intracardiac neurons: regulation by H- and M-currents. Journal of Neurophysiology. 78: 1890-902. PMID 9325358 DOI: 10.1152/Jn.1997.78.4.1890  0.736
1997 Katnik C, Adams DJ. Characterization of ATP-sensitive potassium channels in freshly dissociated rabbit aortic endothelial cells. The American Journal of Physiology. 272: H2507-11. PMID 9176323 DOI: 10.1152/Ajpheart.1997.272.5.H2507  0.778
1997 Poth K, Nutter TJ, Cuevas J, Parker MJ, Adams DJ, Luetje CW. Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 586-96. PMID 8987781 DOI: 10.1523/Jneurosci.17-02-00586.1997  0.815
1996 Cuevas J, Adams DJ. Vasoactive intestinal polypeptide modulation of nicotinic ACh receptor channels in rat intracardiac neurones. The Journal of Physiology. 493: 503-15. PMID 8782112 DOI: 10.1113/Jphysiol.1996.Sp021399  0.65
1995 Gawley RE, Rein KS, Jeglitsch G, Adams DJ, Theodorakis EA, Tiebes J, Nicolaou KC, Baden DG. The relationship of brevetoxin 'length' and A-ring functionality to binding and activity in neuronal sodium channels. Chemistry & Biology. 2: 533-41. PMID 9383457 DOI: 10.1016/1074-5521(95)90187-6  0.824
1995 Rusko J, Van Slooten G, Adams DJ. Caffeine-evoked, calcium-sensitive membrane currents in rabbit aortic endothelial cells. British Journal of Pharmacology. 115: 133-41. PMID 7647967 DOI: 10.1111/J.1476-5381.1995.Tb16330.X  0.803
1995 Katnik C, Adams DJ. An ATP-sensitive potassium conductance in rabbit arterial endothelial cells. The Journal of Physiology. 485: 595-606. PMID 7562603 DOI: 10.1113/Jphysiol.1995.Sp020755  0.768
1995 Nutter TJ, Adams DJ. Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia. The Journal of General Physiology. 105: 701-23. PMID 7561740 DOI: 10.1085/Jgp.105.6.701  0.841
1994 Adams DJ. Ionic channels in vascular endothelial cells Trends in Cardiovascular Medicine. 4: 18-26. PMID 21244905 DOI: 10.1016/1050-1738(94)90021-3  0.354
1994 Demirel E, Rusko J, Laskey RE, Adams DJ, van Breemen C. TEA inhibits ACh-induced EDRF release: endothelial Ca(2+)-dependent K+ channels contribute to vascular tone. The American Journal of Physiology. 267: H1135-41. PMID 8092278 DOI: 10.1152/Ajpheart.1994.267.3.H1135  0.803
1994 Baden DG, Rein KS, Gawley RE, Jeglitsch G, Adams DJ. Is the A-ring lactone of brevetoxin PbTX-3 required for sodium channel orphan receptor binding and activity? Natural Toxins. 2: 212-221. PMID 7952946 DOI: 10.1002/Nt.2620020410  0.819
1994 Cuevas J, Adams DJ. Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. British Journal of Pharmacology. 111: 663-72. PMID 7517326 DOI: 10.1111/J.1476-5381.1994.Tb14789.X  0.647
1993 Xu ZJ, Adams DJ. Alpha-adrenergic modulation of ionic currents in cultured parasympathetic neurons from rat intracardiac ganglia. Journal of Neurophysiology. 69: 1060-70. PMID 8098358 DOI: 10.1152/Jn.1993.69.4.1060  0.599
1993 Cuevas J, Harper AA, Adams DJ. Membrane properties and discharge characteristics of rat intracardiac neurones in vitro: the effect of temperature The Journal of Physiology. 356. DOI: 10.1113/Jphysiol.1993.Sp019755  0.696
1992 Laskey RE, Adams DJ, Cannell M, van Breemen C. Calcium entry-dependent oscillations of cytoplasmic calcium concentration in cultured endothelial cell monolayers. Proceedings of the National Academy of Sciences of the United States of America. 89: 1690-4. PMID 1542661 DOI: 10.1073/Pnas.89.5.1690  0.727
1992 Rusko J, Tanzi F, van Breemen C, Adams DJ. Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block. The Journal of Physiology. 455: 601-21. PMID 1484364 DOI: 10.1113/Jphysiol.1992.Sp019318  0.818
1992 Xu ZJ, Adams DJ. Voltage-dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia. The Journal of Physiology. 456: 425-41. PMID 1338101 DOI: 10.1113/Jphysiol.1992.Sp019344  0.55
1992 Adams DJ, Nutter TJ. Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons. Journal of Physiology, Paris. 86: 67-76. PMID 1285313 DOI: 10.1016/S0928-4257(05)80009-9  0.825
1992 Xu ZJ, Adams DJ. Resting membrane potential and potassium currents in cultured parasympathetic neurones from rat intracardiac ganglia. The Journal of Physiology. 456: 405-24. PMID 1284080 DOI: 10.1113/Jphysiol.1992.Sp019343  0.538
1991 Laskey RE, Adams DJ, Purkerson S, van Breemen C. Cytosolic calcium ion regulation in cultured endothelial cells. Advances in Experimental Medicine and Biology. 304: 257-71. PMID 1803902 DOI: 10.1007/978-1-4684-6003-2_21  0.752
1991 Adams DJ, Bevan S, Terrar DA. Modes of hexamethonium action on acetylcholine receptor channels in frog skeletal muscle. British Journal of Pharmacology. 102: 135-45. PMID 1710523 DOI: 10.1111/J.1476-5381.1991.Tb12144.X  0.389
1991 Fieber LA, Adams DJ. Adenosine triphosphate-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. The Journal of Physiology. 434: 239-56. PMID 1708820 DOI: 10.1113/Jphysiol.1991.Sp018467  0.72
1991 Fieber LA, Adams DJ. Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. The Journal of Physiology. 434: 215-37. PMID 1708819 DOI: 10.1113/Jphysiol.1991.Sp018466  0.739
1990 Seabrook GR, Fieber LA, Adams DJ. Neurotransmission in neonatal rat cardiac ganglion in situ. The American Journal of Physiology. 259: H997-1005. PMID 2171366 DOI: 10.1152/Ajpheart.1990.259.4.H997  0.76
1989 Seabrook GR, Adams DJ. Inhibition of neurally-evoked transmitter release by calcium channel antagonists in rat parasympathetic ganglia. British Journal of Pharmacology. 97: 1125-36. PMID 2571381 DOI: 10.1111/J.1476-5381.1989.Tb12570.X  0.643
1989 Adams DJ, Barakeh J, Laskey R, Van Breemen C. Ion channels and regulation of intracellular calcium in vascular endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 2389-400. PMID 2477294 DOI: 10.1096/Fasebj.3.12.2477294  0.792
1988 Johns A, Freay AD, Adams DJ, Lategan TW, Ryan US, van Breemen C. Role of calcium in the activation of endothelial cells. Journal of Cardiovascular Pharmacology. 12: S119-23. PMID 2469868 DOI: 10.1097/00005344-198800125-00021  0.783
1987 Johns A, Lategan TW, Lodge NJ, Ryan US, Van Breemen C, Adams DJ. Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue & Cell. 19: 733-45. PMID 2449744 DOI: 10.1016/0040-8166(87)90015-2  0.811
1985 Adams DJ, Bevan S. Some properties of acetylcholine receptors in human cultured myotubes. Proceedings of the Royal Society of London. Series B, Biological Sciences. 224: 183-96. PMID 2408280 DOI: 10.1098/Rspb.1985.0028  0.42
1983 Adams DJ, Oxford GS. Interaction of internal anions with potassium channels of the squid giant axon. The Journal of General Physiology. 82: 429-48. PMID 6315855 DOI: 10.1085/Jgp.82.4.429  0.742
1982 Adams DJ, Gage PW, Hamill OP. Inhibitory postsynaptic currents at Aplysia cholinergic synapses: effects of permeant anions and depressant drugs. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 335-50. PMID 6127686 DOI: 10.1098/Rspb.1982.0015  0.732
1981 Adams DJ, Nonner W, Dwyer TM, Hille B. Block of endplate channels by permeant cations in frog skeletal muscle. The Journal of General Physiology. 78: 593-615. PMID 6278050 DOI: 10.1085/Jgp.78.6.593  0.533
1980 Adams DJ, Gage PW. Divalent ion currents and the delayed potassium conductance in an Aplysia neurone. The Journal of Physiology. 304: 297-313. PMID 6255142 DOI: 10.1113/Jphysiol.1980.Sp013325  0.589
1980 Adams DJ, Dwyer TM, Hille B. The permeability of endplate channels to monovalent and divalent metal cations. The Journal of General Physiology. 75: 493-510. PMID 6247423 DOI: 10.1085/Jgp.75.5.493  0.537
1980 Dwyer TM, Adams DJ, Hille B. The permeability of the endplate channel to organic cations in frog muscle. The Journal of General Physiology. 75: 469-92. PMID 6247422 DOI: 10.1085/Jgp.75.5.469  0.562
1979 Adams DJ, Gage PW. Sodium and calcium gating currents in an Aplysia neurone. The Journal of Physiology. 291: 467-81. PMID 480239 DOI: 10.1113/Jphysiol.1979.Sp012826  0.573
1979 Adams DJ, Gage PW. Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. The Journal of Physiology. 289: 143-61. PMID 458645 DOI: 10.1113/Jphysiol.1979.Sp012729  0.581
1979 Adams DJ, Gage PW. Ionic currents in response to membrane depolarization in an Aplysia neurone. The Journal of Physiology. 289: 115-41. PMID 458642 DOI: 10.1113/Jphysiol.1979.Sp012728  0.581
1978 Hamill OP, Adams DJ, Gage PW. An effect of ethanol at a glutamate synapse Clinical and Experimental Pharmacology and Physiology. 5: 275-276. DOI: 10.1111/J.1440-1681.1978.Tb00677.X  0.677
1978 Adams DJ, Gage PW. Asymmetrical displacement currents Nature. 271: 586-587. DOI: 10.1038/271586C0  0.53
1977 Spence I, Adams DJ, Gage PW. Funnel web spider venom produces spontaneous action potentials in nerve. Life Sciences. 20: 243-49. PMID 839959 DOI: 10.1016/0024-3205(77)90318-6  0.553
1977 Adams DJ, Gage PW, Hamill OP. Ethanol reduces excitatory postsynaptic current duration at a crustacean neuromuscular junction. Nature. 266: 739-41. PMID 195212 DOI: 10.1038/266739A0  0.713
1976 Adams DJ, Gage PW. Gating currents associated with sodium and calcium currents in an Aplysia neuron. Science (New York, N.Y.). 192: 783-4. PMID 1265479 DOI: 10.1126/Science.1265479  0.571
1976 Adams DJ, Gage PW, Hamill OP. Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia. Brain Research. 115: 506-11. PMID 974759 DOI: 10.1016/0006-8993(76)90368-1  0.726
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