| Year |
Citation |
Score |
| 2022 |
Ninomiya A, Amano I, Kokubo M, Takatsuru Y, Ishii S, Hirai H, Hosoi N, Koibuchi N. Long-term depression-inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210645119. PMID 36322758 DOI: 10.1073/pnas.2210645119 |
0.341 |
|
| 2022 |
Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1. Cells. 11. PMID 35883691 DOI: 10.3390/cells11142247 |
0.388 |
|
| 2022 |
Watanave M, Takahashi N, Hosoi N, Konno A, Yamamoto H, Yasui H, Kawachi M, Horii T, Matsuzaki Y, Hatada I, Hirai H. Protein kinase Cγ in cerebellar Purkinje cells regulates Ca-activated large-conductance K channels and motor coordination. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35145028 DOI: 10.1073/pnas.2113336119 |
0.305 |
|
| 2021 |
Nagao S, Hirai H, Kano M, Yuzaki M. Masao Ito-A Visionary Neuroscientist with a Passion for the Cerebellum. Neuroscience. 462: 1-3. PMID 33892899 DOI: 10.1016/j.neuroscience.2021.02.028 |
0.492 |
|
| 2021 |
Shuvaev AN, Belozor OS, Mozhei O, Yakovleva DA, Potapenko IV, Shuvaev AN, Smolnikova MV, Salmin VV, Salmina AB, Hirai H, Teschemacher AG, Kasparov S. Chronic optogenetic stimulation of Bergman glia leads to dysfunction of EAAT1 and Purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1. Neurobiology of Disease. 105340. PMID 33753288 DOI: 10.1016/j.nbd.2021.105340 |
0.317 |
|
| 2020 |
Sato M, Ohta T, Morikawa Y, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H, Seki T. Ataxic phenotype and neurodegeneration are triggered by the impairment of chaperone-mediated autophagy in cerebellar neurons. Neuropathology and Applied Neurobiology. PMID 32722888 DOI: 10.1111/Nan.12649 |
0.348 |
|
| 2020 |
Kohara K, Inoue A, Nakano Y, Hirai H, Kobayashi T, Maruyama M, Baba R, Kawashima C. BATTLE: Genetically Engineered Strategies for Split-Tunable Allocation of Multiple Transgenes in the Nervous System. Iscience. 23: 101248. PMID 32629613 DOI: 10.1016/J.Isci.2020.101248 |
0.318 |
|
| 2020 |
Sato M, Ueda E, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H, Seki T. Glucocorticoids negatively regulates chaperone mediated autophagy and microautophagy. Biochemical and Biophysical Research Communications. 528: 199-205. PMID 32487317 DOI: 10.1016/J.Bbrc.2020.04.132 |
0.334 |
|
| 2020 |
Yasui H, Matsuzaki Y, Konno A, Hirai H. Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia. Neuroscience. PMID 32278059 DOI: 10.1016/J.Neuroscience.2020.04.004 |
0.428 |
|
| 2020 |
Chao OY, de Velasco EMF, Pathak SS, Maitra S, Zhang H, Duvick L, Wickman K, Orr HT, Hirai H, Yang YM. Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32179875 DOI: 10.1038/S41386-020-0656-5 |
0.348 |
|
| 2020 |
Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Makuuchi M, Fujita N, Sawada K, Murase S, Watanave M, Hirai H, et al. Mechanical Regulation Underlies Effects of Exercise on Serotonin-Induced Signaling in the Prefrontal Cortex Neurons. Iscience. 23: 100874. PMID 32062453 DOI: 10.1016/J.Isci.2020.100874 |
0.31 |
|
| 2020 |
Oe Y, Wang X, Patriarchi T, Konno A, Ozawa K, Yahagi K, Hirai H, Tian L, McHugh TJ, Hirase H. Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance. Nature Communications. 11: 471. PMID 31980655 DOI: 10.1038/S41467-020-14378-X |
0.354 |
|
| 2020 |
Ninomiya A, Hosoi N, Kokubo M, Amano I, Haijima A, Miyazaki W, Hirai H, Koibuchi N. SAT-454 A Novel Role of Thyroid Hormone Receptor in Synaptic Plasticity in Cerebellar Purkinje Cells Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1706 |
0.414 |
|
| 2019 |
Hosoi N, Shibasaki K, Hosono M, Konno A, Shinoda Y, Kiyonari H, Inoue K, Muramatsu SI, Ishizaki Y, Hirai H, Furuichi T, Sadakata T. Deletion of class II ARFs in mice causes tremor by the Nav1.6 loss in cerebellar Purkinje cell axon initial segments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31201232 DOI: 10.1523/Jneurosci.2002-18.2019 |
0.379 |
|
| 2019 |
Cendelin J, Buffo A, Hirai H, Magrassi L, Mitoma H, Sherrard R, Vozeh F, Manto M. Task Force Paper On Cerebellar Transplantation: Are We Ready to Treat Cerebellar Disorders with Cell Therapy? Cerebellum (London, England). PMID 30607797 DOI: 10.1007/S12311-018-0999-1 |
0.325 |
|
| 2019 |
Watanave M, Hoshino C, Konno A, Fukuzaki Y, Matsuzaki Y, Ishitani T, Hirai H. Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology. Neurobiology of Disease. 121: 263-273. PMID 30343032 DOI: 10.1016/J.Nbd.2018.10.014 |
0.759 |
|
| 2018 |
Watanave M, Matsuzaki Y, Nakajima Y, Ozawa A, Yamada M, Hirai H. Contribution of Thyrotropin-Releasing Hormone to Cerebellar Long-Term Depression and Motor Learning. Frontiers in Cellular Neuroscience. 12: 490. PMID 30618637 DOI: 10.3389/Fncel.2018.00490 |
0.42 |
|
| 2018 |
Shinohara Y, Konno A, Nitta K, Matsuzaki Y, Yasui H, Suwa J, Hiromura K, Hirai H. Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System. Molecular Neurobiology. PMID 30291583 DOI: 10.1007/S12035-018-1366-4 |
0.308 |
|
| 2018 |
Seki T, Sato M, Kibe Y, Ohta T, Oshima M, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H. Lysosomal dysfunction and early glial activation are involved in the pathogenesis of spinocerebellar ataxia type 21 caused by mutant transmembrane protein 240. Neurobiology of Disease. 120: 34-50. PMID 30184469 DOI: 10.1016/J.Nbd.2018.08.022 |
0.433 |
|
| 2018 |
Hirai H, Kano M. Type 1 metabotropic glutamate receptor and its signaling molecules as therapeutic targets for the treatment of cerebellar disorders. Current Opinion in Pharmacology. 38: 51-58. PMID 29525719 DOI: 10.1016/J.Coph.2018.02.002 |
0.4 |
|
| 2018 |
Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Scientific Reports. 8: 2722. PMID 29426875 DOI: 10.1038/S41598-018-21130-5 |
0.343 |
|
| 2018 |
Matsuzaki Y, Konno A, Mochizuki R, Shinohara Y, Nitta K, Okada Y, Hirai H. Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain. Neuroscience Letters. 665: 182-188. PMID 29175632 DOI: 10.1016/J.Neulet.2017.11.049 |
0.316 |
|
| 2018 |
Hirai H. Protein Kinase C in the Cerebellum: Its Significance and Remaining Conundrums. Cerebellum (London, England). 17: 23-27. PMID 29134360 DOI: 10.1007/S12311-017-0898-X |
0.418 |
|
| 2017 |
Takahashi N, Shuvaev AN, Konno A, Matsuzaki Y, Watanave M, Hirai H. Regulatory connection between the expression level of classical protein kinase C and pruning of climbing fibers from cerebellar Purkinje cells. Journal of Neurochemistry. 143: 660-670. PMID 29049849 DOI: 10.1111/Jnc.14239 |
0.382 |
|
| 2017 |
Nitta K, Matsuzaki Y, Konno A, Hirai H. Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates. Molecular Therapy. Methods & Clinical Development. 6: 159-170. PMID 28828391 DOI: 10.1016/J.Omtm.2017.07.006 |
0.338 |
|
| 2017 |
Shinohara Y, Ohtani T, Konno A, Hirai H. Viral Vector-Based Evaluation of Regulatory Regions in the Neuron-Specific Enolase (NSE) Promoter in Mouse Cerebellum In Vivo. Cerebellum (London, England). PMID 28508170 DOI: 10.1007/S12311-017-0866-5 |
0.304 |
|
| 2016 |
Gonçalves N, Simões AT, Prediger RS, Hirai H, Cunha RA, Pereira de Almeida L. Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia. Annals of Neurology. PMID 28032667 DOI: 10.1002/Ana.24867 |
0.428 |
|
| 2016 |
Huda F, Fan Y, Suzuki M, Konno A, Matsuzaki Y, Takahashi N, Chan JK, Hirai H. Fusion of Human Fetal Mesenchymal Stem Cells with "Degenerating" Cerebellar Neurons in Spinocerebellar Ataxia Type 1 Model Mice. Plos One. 11: e0164202. PMID 27802273 DOI: 10.1371/Journal.Pone.0164202 |
0.405 |
|
| 2016 |
Arsenault J, Gholizadeh S, Niibori Y, Pacey LK, Halder SK, Koxhioni E, Konno A, Hirai H, Hampson DR. FMRP Expression Levels in Mouse CNS Neurons Determine Behavioral Phenotype. Human Gene Therapy. PMID 27604541 DOI: 10.1089/Hum.2016.090 |
0.407 |
|
| 2016 |
Shinohara Y, Konno A, Takahashi N, Matsuzaki Y, Kishi S, Hirai H. Viral Vector-Based Dissection of Marmoset GFAP Promoter in Mouse and Marmoset Brains. Plos One. 11: e0162023. PMID 27571575 DOI: 10.1371/Journal.Pone.0162023 |
0.318 |
|
| 2016 |
Shuvaev AN, Hosoi N, Sato Y, Yanagihara D, Hirai H. Progressive impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 model mice. The Journal of Physiology. PMID 27440721 DOI: 10.1113/Jp272950 |
0.443 |
|
| 2016 |
Sawada Y, Konno A, Nagaoka J, Hirai H. Inflammation-induced reversible switch of the neuron-specific enolase promoter from Purkinje neurons to Bergmann glia. Scientific Reports. 6: 27758. PMID 27291422 DOI: 10.1038/Srep27758 |
0.351 |
|
| 2016 |
Yanai T, Kurosawa A, Nikaido Y, Nakajima N, Saito T, Osada H, Konno A, Hirai H, Takeda S. Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 27184081 DOI: 10.1111/Gtc.12378 |
0.315 |
|
| 2016 |
Suto N, Mieda T, Iizuka A, Nakamura K, Hirai H. Morphological and Functional Attenuation of Degeneration of Peripheral Neurons by Mesenchymal Stem Cell-Conditioned Medium in Spinocerebellar Ataxia Type 1-Knock-in Mice. Cns Neuroscience & Therapeutics. PMID 27140210 DOI: 10.1111/Cns.12560 |
0.387 |
|
| 2016 |
Monai H, Ohkura M, Tanaka M, Oe Y, Konno A, Hirai H, Mikoshiba K, Itohara S, Nakai J, Iwai Y, Hirase H. Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain. Nature Communications. 7: 11100. PMID 27000523 DOI: 10.1016/J.Clinph.2016.10.413 |
0.357 |
|
| 2016 |
Matsuzaki Y, Konno A, Mukai R, Honda F, Hirato M, Yoshimoto Y, Hirai H. Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors. Molecular Neurobiology. PMID 26884266 DOI: 10.1007/S12035-016-9777-6 |
0.341 |
|
| 2016 |
Conceição M, Mendonça L, Nóbrega C, Gomes C, Costa P, Hirai H, Moreira JN, Lima MC, Manjunath N, Pereira de Almeida L. Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype. Biomaterials. 82: 124-37. PMID 26757259 DOI: 10.1016/J.Biomaterials.2015.12.021 |
0.315 |
|
| 2015 |
Mieda T, Suto N, Iizuka A, Matsuura S, Iizuka H, Takagishi K, Nakamura K, Hirai H. Mesenchymal stem cells attenuate peripheral neuronal degeneration in spinocerebellar ataxia type 1 knockin mice. Journal of Neuroscience Research. PMID 26707550 DOI: 10.1002/Jnr.23698 |
0.342 |
|
| 2015 |
Ageta-Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, Nishioka T, Kaibuchi K, Hattori S, Miyakawa T, Tanaka K, Huda F, Hirai H, Hashimoto K, Watanabe M, et al. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nature Communications. 6: 10090. PMID 26657011 DOI: 10.1038/Ncomms10090 |
0.394 |
|
| 2015 |
Nóbrega C, Carmo-Silva S, Albuquerque D, Vasconcelos-Ferreira A, Vijayakumar UG, Mendonça L, Hirai H, Pereira de Almeida L. Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease. Brain : a Journal of Neurology. PMID 26490332 DOI: 10.1093/Brain/Awv298 |
0.331 |
|
| 2015 |
Duarte-Neves J, Gonçalves N, Cunha-Santos J, Simões AT, den Dunnen WF, Hirai H, Kügler S, Cavadas C, Pereira de Almeida L. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease. Human Molecular Genetics. 24: 5451-63. PMID 26220979 DOI: 10.1093/Hmg/Ddv271 |
0.361 |
|
| 2015 |
Iizuka A, Matsuzaki Y, Konno A, Hirai H. Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα. Brain Structure & Function. PMID 26122696 DOI: 10.1007/S00429-015-1077-9 |
0.443 |
|
| 2015 |
Iizuka A, Nakamura K, Hirai H. Long-term oral administration of the NMDA receptor antagonist memantine extends life span in spinocerebellar ataxia type 1 knock-in mice. Neuroscience Letters. 592: 37-41. PMID 25725171 DOI: 10.1016/J.Neulet.2015.02.055 |
0.441 |
|
| 2015 |
Kusakari S, Saitow F, Ago Y, Shibasaki K, Sato-Hashimoto M, Matsuzaki Y, Kotani T, Murata Y, Hirai H, Matsuda T, Suzuki H, Matozaki T, Ohnishi H. Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice. Molecular and Cellular Biology. 35: 1557-72. PMID 25713104 DOI: 10.1128/Mcb.01339-14 |
0.401 |
|
| 2015 |
Mendonça LS, Nóbrega C, Hirai H, Kaspar BK, Pereira de Almeida L. Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice. Brain : a Journal of Neurology. 138: 320-35. PMID 25527827 DOI: 10.1093/Brain/Awu352 |
0.384 |
|
| 2015 |
Uesaka N, Uchigashima M, Mikuni T, Hirai H, Watanabe M, Kano M. Retrograde signaling for climbing fiber synapse elimination. Cerebellum (London, England). 14: 4-7. PMID 25338972 DOI: 10.1007/S12311-014-0615-Y |
0.382 |
|
| 2015 |
Nakamura K, Mieda T, Suto N, Matsuura S, Hirai H. Mesenchymal stem cells as a potential therapeutic tool for spinocerebellar ataxia. Cerebellum (London, England). 14: 165-70. PMID 25280585 DOI: 10.1007/S12311-014-0604-1 |
0.339 |
|
| 2015 |
Takahashi H, Adachi N, Shirafuji T, Danno S, Ueyama T, Vendruscolo M, Shuvaev AN, Sugimoto T, Seki T, Hamada D, Irie K, Hirai H, Sakai N, Saito N. Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein. Human Molecular Genetics. 24: 525-39. PMID 25217572 DOI: 10.1093/Hmg/Ddu472 |
0.304 |
|
| 2015 |
Suto N, Nakamura K, Hirai H. Exercise Differentially Affects Cerebellar Cytotoxic Microglia in Spinocerebellar Ataxia Model Mice The Kitakanto Medical Journal. 65: 123-124. DOI: 10.2974/Kmj.65.123 |
0.306 |
|
| 2015 |
Huda F, Fan Y, Konno A, Matsuzaki Y, Takahashi N, Chan J, Hirai H. 598. Fusion of Mesenchymal Stem Cells Exclusively with “Degenerating” Cerebellar Neurons in Spinocerebellar Ataxia Type 1 Model Mice Molecular Therapy. 23: S237. DOI: 10.1016/S1525-0016(16)34207-1 |
0.409 |
|
| 2014 |
Huda F, Konno A, Matsuzaki Y, Goenawan H, Miyake K, Shimada T, Hirai H. Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model. Molecular Therapy. Methods & Clinical Development. 1: 14032. PMID 26015973 DOI: 10.1038/Mtm.2014.32 |
0.393 |
|
| 2014 |
Yoshihara S, Takahashi H, Nishimura N, Kinoshita M, Asahina R, Kitsuki M, Tatsumi K, Furukawa-Hibi Y, Hirai H, Nagai T, Yamada K, Tsuboi A. Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons. Cell Reports. 8: 843-57. PMID 25088421 DOI: 10.1016/J.Celrep.2014.06.056 |
0.301 |
|
| 2014 |
Saida H, Matsuzaki Y, Takayama K, Iizuka A, Konno A, Yanagi S, Hirai H. One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice. Gene Therapy. 21: 820-7. PMID 24989813 DOI: 10.1038/Gt.2014.60 |
0.399 |
|
| 2014 |
Uesaka N, Uchigashima M, Mikuni T, Nakazawa T, Nakao H, Hirai H, Aiba A, Watanabe M, Kano M. Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain. Science (New York, N.Y.). 344: 1020-3. PMID 24831527 DOI: 10.1126/Science.1252514 |
0.381 |
|
| 2014 |
Okonogi N, Nakamura K, Suzuki Y, Suto N, Suzue K, Kaminuma T, Nakano T, Hirai H. Cranial irradiation induces bone marrow-derived microglia in adult mouse brain tissue. Journal of Radiation Research. 55: 713-9. PMID 24706998 DOI: 10.1093/Jrr/Rru015 |
0.347 |
|
| 2014 |
Matsuzaki Y, Oue M, Hirai H. Generation of a neurodegenerative disease mouse model using lentiviral vectors carrying an enhanced synapsin I promoter. Journal of Neuroscience Methods. 223: 133-43. PMID 24361760 DOI: 10.1016/J.Jneumeth.2013.12.004 |
0.373 |
|
| 2014 |
Matsuura S, Shuvaev AN, Iizuka A, Nakamura K, Hirai H. Mesenchymal stem cells ameliorate cerebellar pathology in a mouse model of spinocerebellar ataxia type 1. Cerebellum (London, England). 13: 323-30. PMID 24242763 DOI: 10.1007/S12311-013-0536-1 |
0.398 |
|
| 2014 |
Irie T, Matsuzaki Y, Sekino Y, Hirai H. Kv3.3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells. The Journal of Physiology. 592: 229-47. PMID 24218544 DOI: 10.1113/Jphysiol.2013.264309 |
0.601 |
|
| 2014 |
Konno A, Shuvaev AN, Miyake N, Miyake K, Iizuka A, Matsuura S, Huda F, Nakamura K, Yanagi S, Shimada T, Hirai H. Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar Purkinje cells. Cerebellum (London, England). 13: 29-41. PMID 23955261 DOI: 10.1007/S12311-013-0516-5 |
0.497 |
|
| 2013 |
Miki T, Hirai H, Takahashi T. Activity-dependent neurotrophin signaling underlies developmental switch of Ca2+ channel subtypes mediating neurotransmitter release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18755-63. PMID 24285882 DOI: 10.1523/Jneurosci.3161-13.2013 |
0.346 |
|
| 2013 |
Nascimento-Ferreira I, Nóbrega C, Vasconcelos-Ferreira A, Onofre I, Albuquerque D, Aveleira C, Hirai H, Déglon N, Pereira de Almeida L. Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease. Brain : a Journal of Neurology. 136: 2173-88. PMID 23801739 DOI: 10.1093/Brain/Awt144 |
0.389 |
|
| 2013 |
Mikuni T, Uesaka N, Okuno H, Hirai H, Deisseroth K, Bito H, Kano M. Arc/Arg3.1 is a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum. Neuron. 78: 1024-35. PMID 23791196 DOI: 10.1016/J.Neuron.2013.04.036 |
0.367 |
|
| 2013 |
Yamaura H, Hirai H, Yanagihara D. Postural dysfunction in a transgenic mouse model of spinocerebellar ataxia type 3. Neuroscience. 243: 126-35. PMID 23567815 DOI: 10.1016/J.Neuroscience.2013.03.044 |
0.346 |
|
| 2013 |
Nóbrega C, Nascimento-Ferreira I, Onofre I, Albuquerque D, Hirai H, Déglon N, de Almeida LP. Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice. Plos One. 8: e52396. PMID 23349684 DOI: 10.1371/Journal.Pone.0052396 |
0.413 |
|
| 2013 |
Takechi Y, Mieda T, Iizuka A, Toya S, Suto N, Takagishi K, Nakazato Y, Nakamura K, Hirai H. Impairment of spinal motor neurons in spinocerebellar ataxia type 1-knock-in mice. Neuroscience Letters. 535: 67-72. PMID 23328439 DOI: 10.1016/J.Neulet.2012.12.057 |
0.387 |
|
| 2013 |
Suto N, Nakamura K, Hirai H. Exercise differentially affects cerebellar cytotoxic microglia in spinocerebellar ataxia model mice Kitakanto Medical Journal. 63: 209-215. DOI: 10.2974/Kmj.63.209 |
0.306 |
|
| 2012 |
Oue M, Handa H, Matsuzaki Y, Suzue K, Murakami H, Hirai H. The murine stem cell virus promoter drives correlated transgene expression in the leukocytes and cerebellar Purkinje cells of transgenic mice. Plos One. 7: e51015. PMID 23226450 DOI: 10.1371/Journal.Pone.0051015 |
0.383 |
|
| 2012 |
Goenawan H, Hirai H. Modulation of lentiviral vector tropism in cerebellar Purkinje cells in vivo by a lysosomal cysteine protease cathepsin K. Journal of Neurovirology. 18: 521-31. PMID 23070819 DOI: 10.1007/S13365-012-0134-X |
0.366 |
|
| 2012 |
Uesaka N, Mikuni T, Hashimoto K, Hirai H, Sakimura K, Kano M. Organotypic coculture preparation for the study of developmental synapse elimination in mammalian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11657-70. PMID 22915109 DOI: 10.1523/Jneurosci.1097-12.2012 |
0.4 |
|
| 2012 |
Yoshihara S, Takahashi H, Nishimura N, Naritsuka H, Shirao T, Hirai H, Yoshihara Y, Mori K, Stern PL, Tsuboi A. 5T4 glycoprotein regulates the sensory input-dependent development of a specific subtype of newborn interneurons in the mouse olfactory bulb. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2217-26. PMID 22323733 DOI: 10.1523/Jneurosci.5907-11.2012 |
0.315 |
|
| 2012 |
Jin D, Muramatsu S, Shimizu N, Yokoyama S, Hirai H, Yamada K, Liu HX, Higashida C, Hashii M, Higashida A, Asano M, Ohkuma S, Higashida H. Dopamine release via the vacuolar ATPase V0 sector c-subunit, confirmed in N18 neuroblastoma cells, results in behavioral recovery in hemiparkinsonian mice. Neurochemistry International. 61: 907-12. PMID 22265874 DOI: 10.1016/J.Neuint.2011.12.021 |
0.353 |
|
| 2012 |
Hirai H. Basic research on cerebellar gene therapy using lentiviral vectors. Cerebellum (London, England). 11: 443-5. PMID 22120847 DOI: 10.1007/S12311-011-0330-X |
0.35 |
|
| 2011 |
Shuvaev AN, Horiuchi H, Seki T, Goenawan H, Irie T, Iizuka A, Sakai N, Hirai H. Mutant PKCγ in spinocerebellar ataxia type 14 disrupts synapse elimination and long-term depression in Purkinje cells in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14324-34. PMID 21976518 DOI: 10.1523/Jneurosci.5530-10.2011 |
0.619 |
|
| 2011 |
Mitsumura K, Hosoi N, Furuya N, Hirai H. Disruption of metabotropic glutamate receptor signalling is a major defect at cerebellar parallel fibre-Purkinje cell synapses in staggerer mutant mice. The Journal of Physiology. 589: 3191-209. PMID 21558162 DOI: 10.1113/Jphysiol.2011.207563 |
0.457 |
|
| 2011 |
Hirai H, Anton S, Seki T, Sakai N. Disruption of climbing fiber synapse elimination and LTD expression in cerebellar Purkinje cells by mutant γPKC found in spinocerebellar ataxia type 14 Neuroscience Research. 71: e57. DOI: 10.1016/J.Neures.2011.07.241 |
0.386 |
|
| 2011 |
Shuvaev AN, Horiuchi H, Seki T, Hanna G, Irie T, Iizuka A, Sakai N, Hirai H. Mutant γPKC found in spinocerebellar ataxia type 14 disrupts synapse elimination and long-term depression in Purkinje cells in vivo Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1272 |
0.562 |
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| 2011 |
Hosoi N, Mitsumura K, Hirai H. Impairment of mGluR signaling at cerebellar parallel fiber–Purkinje cell synapses in staggerer mutant mice Neuroscience Research. 71: e246. DOI: 10.1016/J.Neures.2011.07.1075 |
0.428 |
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| 2010 |
Sasaki J, Kofuji S, Itoh R, Momiyama T, Takayama K, Murakami H, Chida S, Tsuya Y, Takasuga S, Eguchi S, Asanuma K, Horie Y, Miura K, Davies EM, Mitchell C, ... ... Hirai H, et al. The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature. 465: 497-501. PMID 20463662 DOI: 10.1038/Nature09023 |
0.406 |
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| 2010 |
Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev AN, Koyama C, Hirai H. High transgene expression by lentiviral vectors causes maldevelopment of Purkinje cells in vivo. Cerebellum (London, England). 9: 291-302. PMID 20178014 DOI: 10.1007/S12311-010-0161-1 |
0.405 |
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| 2009 |
Oue M, Mitsumura K, Torashima T, Koyama C, Yamaguchi H, Furuya N, Hirai H. Characterization of mutant mice that express polyglutamine in cerebellar Purkinje cells. Brain Research. 1255: 9-17. PMID 19103174 DOI: 10.1016/J.Brainres.2008.12.014 |
0.44 |
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| 2009 |
Iizuka A, Torashima T, Mitsumura K, Koyama C, Iino M, Hirai H. Lentiviral vector-mediated rescue of motor behavior in hereditary ataxic mice Neuroscience Research. 65: S96. DOI: 10.1016/J.Neures.2009.09.406 |
0.334 |
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| 2009 |
Sawada Y, Kajiwara G, Torashima T, Takayama K, Horiuchi H, Iizuka A, Mitsumura K, Hirai H. Influence of lentiviral vector infection on the development of cerebellar Purkinje cells in vivo Neuroscience Research. 65: S89-S90. DOI: 10.1016/J.Neures.2009.09.366 |
0.318 |
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| 2009 |
Hirai H, Torashima T, Iizuka A. Progress of the δ2 glutamate receptor research from the viewpoint of functional domains Neuroscience Research. 65: S9. DOI: 10.1016/J.Neures.2009.09.1517 |
0.302 |
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| 2009 |
Shuvaev A, Horiuchi H, Iizuka A, Irie T, Iino M, Seki T, Sakai N, Hirai H. A PKCγ mutation in spinocerebellar ataxia type 14 impairs PKC functions in a dominant-negative manner in cerebellar Purkinje cells in vivo Neuroscience Research. 65: S247. DOI: 10.1016/J.Neures.2009.09.1401 |
0.577 |
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| 2008 |
Sato T, Torashima T, Sugihara K, Hirai H, Asano M, Yoshioka K. The scaffold protein JSAP1 regulates proliferation and differentiation of cerebellar granule cell precursors by modulating JNK signaling. Molecular and Cellular Neurosciences. 39: 569-78. PMID 18804538 DOI: 10.1016/J.Mcn.2008.08.003 |
0.363 |
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| 2008 |
Takayama K, Torashima T, Horiuchi H, Hirai H. Purkinje-cell-preferential transduction by lentiviral vectors with the murine stem cell virus promoter. Neuroscience Letters. 443: 7-11. PMID 18675313 DOI: 10.1016/J.Neulet.2008.07.058 |
0.364 |
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| 2008 |
Han L, Suda M, Tsuzuki K, Wang R, Ohe Y, Hirai H, Watanabe T, Takeuchi T, Hosaka M. A large form of secretogranin III functions as a sorting receptor for chromogranin A aggregates in PC12 cells. Molecular Endocrinology (Baltimore, Md.). 22: 1935-49. PMID 18483175 DOI: 10.1210/Me.2008-0006 |
0.334 |
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| 2008 |
Hirai H. Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors. Cerebellum (London, England). 7: 273-8. PMID 18418690 DOI: 10.1007/S12311-008-0012-5 |
0.378 |
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| 2008 |
Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H. Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia. Embo Reports. 9: 393-9. PMID 18344973 DOI: 10.1038/Embor.2008.31 |
0.427 |
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| 2007 |
Nakamura K, Hirai H, Torashima T, Miyazaki T, Tsurui H, Xiu Y, Ohtsuji M, Lin QS, Tsukamoto K, Nishimura H, Ono M, Watanabe M, Hirose S. CD3 and immunoglobulin G Fc receptor regulate cerebellar functions. Molecular and Cellular Biology. 27: 5128-34. PMID 17502348 DOI: 10.1128/Mcb.01072-06 |
0.425 |
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| 2007 |
Kakegawa W, Miyazaki T, Hirai H, Motohashi J, Mishina M, Watanabe M, Yuzaki M. Ca2+ permeability of the channel pore is not essential for the delta2 glutamate receptor to regulate synaptic plasticity and motor coordination. The Journal of Physiology. 579: 729-35. PMID 17255161 DOI: 10.1113/Jphysiol.2006.127100 |
0.618 |
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| 2006 |
Hisatsune C, Kuroda Y, Akagi T, Torashima T, Hirai H, Hashikawa T, Inoue T, Mikoshiba K. Inositol 1,4,5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10916-24. PMID 17050730 DOI: 10.1523/Jneurosci.3269-06.2006 |
0.44 |
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| 2006 |
Torashima T, Yamada N, Itoh M, Yamamoto A, Hirai H. Exposure of lentiviral vectors to subneutral pH shifts the tropism from Purkinje cell to Bergmann glia. The European Journal of Neuroscience. 24: 371-80. PMID 16836635 DOI: 10.1111/J.1460-9568.2006.04927.X |
0.347 |
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| 2006 |
Torashima T, Okoyama S, Nishizaki T, Hirai H. In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors. Brain Research. 1082: 11-22. PMID 16516872 DOI: 10.1016/J.Brainres.2006.01.104 |
0.375 |
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| 2006 |
Qin Q, Inatome R, Hotta A, Kojima M, Yamamura H, Hirai H, Yoshizawa T, Tanaka H, Fukami K, Yanagi S. A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein. The Journal of Cell Biology. 172: 497-504. PMID 16461359 DOI: 10.1083/Jcb.200505079 |
0.309 |
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| 2005 |
Hirai H, Pang Z, Bao D, Miyazaki T, Li L, Miura E, Parris J, Rong Y, Watanabe M, Yuzaki M, Morgan JI. Cbln1 is essential for synaptic integrity and plasticity in the cerebellum. Nature Neuroscience. 8: 1534-41. PMID 16234806 DOI: 10.1038/Nn1576 |
0.628 |
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| 2005 |
Hirai H, Miyazaki T, Kakegawa W, Matsuda S, Mishina M, Watanabe M, Yuzaki M. Rescue of abnormal phenotypes of the delta2 glutamate receptor-null mice by mutant delta2 transgenes. Embo Reports. 6: 90-5. PMID 15592450 DOI: 10.1038/Sj.Embor.7400312 |
0.633 |
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| 2003 |
Hirai H, Launey T, Mikawa S, Torashima T, Yanagihara D, Kasaura T, Miyamoto A, Yuzaki M. New role of delta2-glutamate receptors in AMPA receptor trafficking and cerebellar function. Nature Neuroscience. 6: 869-76. PMID 12833050 DOI: 10.1038/Nn1086 |
0.629 |
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| 2003 |
Matsuda S, Launey T, Mikawa S, Hirai H. Erratum: Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons (EMBO Journal (2000) 19 (2765-2774)) The Embo Journal. 22. DOI: 10.1093/Emboj/Cdg049 |
0.324 |
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| 2002 |
Matsuda S, Mikawa S, Hirai H. Phosphorylation of Serine‐880 in GluR2 by Protein Kinase C Prevents Its C Terminus from Binding with Glutamate Receptor‐Interacting Protein Journal of Neurochemistry. 73: 1765-1768. PMID 10501226 DOI: 10.1046/J.1471-4159.1999.731765.X |
0.353 |
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| 2002 |
Hirai H, Launey T, Mikawa S, Yanagihara D, Kasaura T, Miyamoto A, Yuzaki M. Antibody against a putative ligand-binding site reveals delta2 glutamate receptor function Annals of the New York Academy of Sciences. 978: 519. DOI: 10.1111/J.1749-6632.2002.Tb07600.X |
0.542 |
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| 2001 |
Hirai H. Ca2+-dependent regulation of synaptic delta2 glutamate receptor density in cultured rat Purkinje neurons. European Journal of Neuroscience. 14: 73-82. PMID 11488951 DOI: 10.1046/J.0953-816X.2001.01630.X |
0.386 |
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| 2001 |
Hirai H. Modification of AMPA receptor clustering regulates cerebellar synaptic plasticity. Neuroscience Research. 39: 261-7. PMID 11248365 DOI: 10.1016/S0168-0102(00)00237-6 |
0.392 |
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| 2000 |
Hirai H, Launey T. The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5217-24. PMID 10884305 DOI: 10.1523/Jneurosci.20-14-05217.2000 |
0.413 |
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| 2000 |
Matsuda S, Launey T, Mikawa S, Hirai H. Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons. The Embo Journal. 19: 2765-74. PMID 10856222 DOI: 10.1093/Emboj/19.12.2765 |
0.382 |
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| 2000 |
Hirai H. Clustering of δ glutamate receptors is regulated by the actin cytoskeleton in the dendritic spines of cultured rat Purkinje cells European Journal of Neuroscience. 12: 563-570. PMID 10712635 DOI: 10.1046/J.1460-9568.2000.00938.X |
0.365 |
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| 2000 |
Hirai H, Matsuda S. Interaction of the C-terminal domain of delta glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells. Neuroscience Research. 34: 281-7. PMID 10576550 DOI: 10.1016/S0168-0102(99)00061-9 |
0.379 |
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| 1999 |
Hirai H, Yoshioka K, Yamada K. Regulation of Phosphatidylcholine Biosynthesis by mGluR1α Expressed in Human Embryonic Kidney 293 Cells— A 31P-NMR Study Molecular and Cellular Neuroscience. 14: 444-454. PMID 10656252 DOI: 10.1006/Mcne.1999.0797 |
0.38 |
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| 1999 |
Matsuda S, Hirai H. The clustering of NMDA receptor NR1 subunit is regulated by the interaction between the C-terminal exon cassettes and the cytoskeleton. Neuroscience Research. 34: 157-63. PMID 10515258 DOI: 10.1016/S0168-0102(99)00046-2 |
0.341 |
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| 1998 |
Hirai H, Torashima T, Ito M, Yoshioka K, Yamada K. Phospholipid metabolism activated by the stimulation of glutamate receptors in HEK 293 cells stably expressing glutamate receptors-31P-NMR study- Neuroscience Research. 31: S87. DOI: 10.1016/S0168-0102(98)81894-4 |
0.344 |
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| 1997 |
Laube B, Hirai H, Sturgess M, Betz H, Kuhse J. Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron. 18: 493-503. PMID 9115742 DOI: 10.1016/S0896-6273(00)81249-0 |
0.321 |
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