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Amer Alam - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Alam A, Locher KP. Structure and Mechanism of Human ABC Transporters. Annual Review of Biophysics. PMID 36737602 DOI: 10.1146/annurev-biophys-111622-091232  0.562
2020 Nosol K, Romane K, Irobalieva RN, Alam A, Kowal J, Fujita N, Locher KP. Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proceedings of the National Academy of Sciences of the United States of America. PMID 33020312 DOI: 10.1073/pnas.2010264117  0.591
2019 Olsen JA, Alam A, Kowal J, Stieger B, Locher KP. Structure of the human lipid exporter ABCB4 in a lipid environment. Nature Structural & Molecular Biology. PMID 31873305 DOI: 10.1038/S41594-019-0354-3  0.591
2019 Alam A, Kowal J, Broude E, Roninson I, Locher KP. Structural insight into substrate and inhibitor discrimination by human P-glycoprotein. Science (New York, N.Y.). 363: 753-756. PMID 30765569 DOI: 10.1126/Science.Aav7102  0.613
2018 Alam A, Küng R, Kowal J, McLeod RA, Tremp N, Broude EV, Roninson IB, Stahlberg H, Locher KP. Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29440498 DOI: 10.2210/Pdb6Fn4/Pdb  0.623
2016 Alam A, Woo JS, Schmitz J, Prinz B, Root K, Chen F, Bloch JS, Zenobi R, Locher KP. Structural basis of transcobalamin recognition by human CD320 receptor. Nature Communications. 7: 12100. PMID 27411955 DOI: 10.1038/Ncomms12100  0.542
2011 Alam A, Jiang Y. Structural studies of ion selectivity in tetrameric cation channels Journal of General Physiology. 137: 397-403. PMID 21518828 DOI: 10.1085/Jgp.201010546  0.687
2011 Derebe MG, Zeng W, Li Y, Alam A, Jiang Y. Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proceedings of the National Academy of Sciences of the United States of America. 108: 592-7. PMID 21187429 DOI: 10.1073/Pnas.1013643108  0.723
2011 Derebe MG, Sauer DB, Zeng W, Alam A, Shi N, Jiang Y. Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proceedings of the National Academy of Sciences of the United States of America. 108: 598-602. PMID 21187421 DOI: 10.1073/Pnas.1013636108  0.708
2009 Alam A, Jiang Y. High-resolution structure of the open NaK channel Nature Structural and Molecular Biology. 16: 30-34. PMID 19098917 DOI: 10.1038/Nsmb.1531  0.679
2009 Alam A, Jiang Y. Structural analysis of ion selectivity in the NaK channel Nature Structural and Molecular Biology. 16: 35-41. PMID 19098915 DOI: 10.1038/Nsmb.1537  0.682
2007 Alam A, Shi N, Jiang Y. Structural insight into Ca2+ specificity in tetrameric cation channels. Proceedings of the National Academy of Sciences of the United States of America. 104: 15334-9. PMID 17878296 DOI: 10.1073/Pnas.0707324104  0.636
2006 Shi N, Ye S, Alam A, Chen L, Jiang Y. Atomic structure of a Na+- and K+-conducting channel. Nature. 440: 570-4. PMID 16467789 DOI: 10.1038/Nature04508  0.706
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