Year |
Citation |
Score |
2023 |
Maddeboina K, Jonnalagadda SK, Morsy A, Duan L, Chhonker YS, Murry DJ, Penning TM, Trippier PC. Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model. Journal of Medicinal Chemistry. PMID 37428858 DOI: 10.1021/acs.jmedchem.3c00732 |
0.367 |
|
2023 |
Huwaimel BI, Jonnalagadda SK, Jonnalagadda S, Kumari S, Nocentini A, Supuran CT, Trippier PC. Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold. Drug Development Research. PMID 36872587 DOI: 10.1002/ddr.22049 |
0.766 |
|
2022 |
Huwaimel BI, Jonnalagadda S, Jonnalagadda S, Zahra FT, Nocentini A, Supuran CT, Mikelis CM, Trippier PC. Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation. Bioorganic & Medicinal Chemistry. 67: 116805. PMID 35635929 DOI: 10.1016/j.bmc.2022.116805 |
0.806 |
|
2022 |
Jonnalagadda SK, Huwaimel BI, Jonnalagadda S, Garrison JC, Trippier PC. Access to Highly Strained Tricyclic Ketals Derived from Coumarins. The Journal of Organic Chemistry. 87: 4476-4482. PMID 35258961 DOI: 10.1021/acs.joc.2c00018 |
0.755 |
|
2021 |
Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Schumacher TJ, Gardner ZS, Palle H, Mani C, Rumbley J, Mereddy VR. Synthesis and biological evaluation of N, N-dialkylcarboxy coumarin-NO donor conjugates as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. 128411. PMID 34626786 DOI: 10.1016/j.bmcl.2021.128411 |
0.822 |
|
2021 |
Penning TM, Jonnalagadda S, Trippier PC, Rižner TL. Aldo-Keto Reductases and Cancer Drug Resistance. Pharmacological Reviews. 73: 1150-1171. PMID 34312303 DOI: 10.1124/pharmrev.120.000122 |
0.312 |
|
2021 |
Ronayne CT, Jonnalagadda SK, Jonnalagadda S, Nelson GL, Solano LN, Palle H, Mani C, Rumbley J, Holy J, Mereddy VR. Synthesis and biological evaluation of a novel anticancer agent CBISC that induces DNA damage response and diminishes levels of mutant-p53. Biochemical and Biophysical Research Communications. 562: 127-132. PMID 34051576 DOI: 10.1016/j.bbrc.2021.05.062 |
0.821 |
|
2020 |
Solano LN, Nelson GL, Ronayne CT, Jonnalagadda S, Jonnalagadda SK, Kottke K, Chitren R, Johnson JL, Pandey MK, Jonnalagadda SC, Mereddy VR. Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents. Scientific Reports. 10: 17969. PMID 33087745 DOI: 10.1038/s41598-020-74572-1 |
0.828 |
|
2020 |
Jonnalagadda SK, Wielenberg K, Ronayne CT, Jonnalagadda S, Kiprof P, Jonnalagadda SC, Mereddy VR. Synthesis and biological evaluation of arylphosphonium-benzoxaborole conjugates as novel anticancer agents. Bioorganic & Medicinal Chemistry Letters. 30: 127259. PMID 32527557 DOI: 10.1016/J.Bmcl.2020.127259 |
0.825 |
|
2020 |
Sadeghzadeh M, Wenzel B, Gündel D, Deuther-Conrad W, Toussaint M, Moldovan RP, Fischer S, Ludwig FA, Teodoro R, Jonnalagadda S, Jonnalagadda SK, Schüürmann G, Mereddy VR, Drewes LR, Brust P. Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging. Molecules (Basel, Switzerland). 25. PMID 32423056 DOI: 10.3390/Molecules25102309 |
0.783 |
|
2019 |
Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Rumbley J, Holy J, Rose-Hellekant T, Drewes LR, Mereddy VR. Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment. Scientific Reports. 9: 18266. PMID 31797891 DOI: 10.1038/S41598-019-54709-7 |
0.822 |
|
2019 |
Jonnalagadda S, Jonnalagadda SK, Ronayne CT, Nelson GL, Solano LN, Rumbley J, Holy J, Mereddy VR, Drewes LR. Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors. Oncotarget. 10: 2355-2368. PMID 31040927 DOI: 10.18632/Oncotarget.26760 |
0.829 |
|
2019 |
Sadeghzadeh M, Moldovan RP, Fischer S, Wenzel B, Ludwig FA, Teodoro R, Deuther-Conrad W, Jonnalagadda S, Jonnalagadda SK, Gudelis E, Šačkus A, Higuchi K, Ganapathy V, Mereddy VR, Drewes LR, et al. Development and radiosynthesis of the first F-labeled inhibitor of monocarboxylate transporters (MCTs). Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31017677 DOI: 10.1002/Jlcr.3739 |
0.775 |
|
2018 |
Nelson GL, Williams MJ, Jonnalagadda S, Alam MA, Mereddy G, Johnson JL, Jonnalagadda SK. Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents. International Journal of Medicinal Chemistry. 2018: 5758076. PMID 30410798 DOI: 10.1155/2018/5758076 |
0.839 |
|
2017 |
Ronayne CT, Solano LN, Nelson GL, Lueth EA, Hubbard SL, Schumacher TJ, Gardner ZS, Jonnalagadda SK, Gurrapu S, Holy J, Mereddy VR. Synthesis and biological evaluation of 2-alkoxycarbonylallyl esters as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. PMID 28129978 DOI: 10.1016/J.Bmcl.2017.01.037 |
0.803 |
|
2016 |
Alam MA, Arora K, Gurrapu S, Jonnalagadda SK, Nelson GL, Kiprof P, Jonnalagadda SC, Mereddy VR. Synthesis and evaluation of functionalized benzoboroxoles as potential anti-tuberculosis agents. Tetrahedron. 72: 3795-3801. PMID 27642196 DOI: 10.1016/J.Tet.2016.03.038 |
0.829 |
|
2016 |
Gurrapu S, Jonnalagadda SK, Alam MA, Ronayne CT, Nelson GL, Solano LN, Lueth EA, Drewes LR, Mereddy VR. Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. PMID 27241692 DOI: 10.1016/J.Bmcl.2016.05.054 |
0.797 |
|
2016 |
Alam MA, Arora K, Gurrapu S, Jonnalagadda SK, Nelson GL, Kiprof P, Jonnalagadda SC, Mereddy VR. Synthesis and evaluation of functionalized benzoboroxoles as potential anti-tuberculosis agents Tetrahedron. DOI: 10.1016/j.tet.2016.03.038 |
0.83 |
|
2015 |
Solano LN, Nelson GL, Ronayne CT, Lueth EA, Foxley MA, Jonnalagadda SK, Gurrapu S, Mereddy VR. Synthesis, in vitro, and in vivo evaluation of novel functionalized quaternary ammonium curcuminoids as potential anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 25: 5777-80. PMID 26561365 DOI: 10.1016/J.Bmcl.2015.10.061 |
0.801 |
|
2015 |
Gurrapu S, Jonnalagadda SK, Alam MA, Nelson GL, Sneve MG, Drewes LR, Mereddy VR. Monocarboxylate transporter 1 inhibitors as potential anticancer agents. Acs Medicinal Chemistry Letters. 6: 558-61. PMID 26005533 DOI: 10.1021/Acsmedchemlett.5B00049 |
0.844 |
|
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