Scott E. Hemby - Publications

Wake Forest University School of Medicine, Winston-Salem, NC, United States 
synaptic pathology, cocaine, schizophrenia, antipsychotics, monkey, human, rat

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hemby SE, McIntosh S, Leon F, Cutler SJ, McCurdy CR. Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine. Addiction Biology. PMID 29949228 DOI: 10.1111/adb.12639  0.8
2018 Chen R, McIntosh S, Hemby SE, Sun H, Sexton T, Martin T, Childers SR. High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. Neuroscience Letters. PMID 29454035 DOI: 10.1016/j.neulet.2018.02.026  0.8
2015 McIntosh S, Sexton T, Pattison LP, Childers SR, Hemby SE. Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 25749646 DOI: 10.1007/s11481-015-9594-0  1
2015 MacDonald ML, Ding Y, Newman J, Hemby S, Penzes P, Lewis DA, Yates NA, Sweet RA. Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia. Biological Psychiatry. 77: 959-68. PMID 25433904 DOI: 10.1016/j.biopsych.2014.09.006  1
2014 Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, et al. Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Molecular Psychiatry. PMID 25330739 DOI: 10.1038/mp.2014.115  1
2014 Daunais JB, Davenport AT, Helms CM, Gonzales SW, Hemby SE, Friedman DP, Farro JP, Baker EJ, Grant KA. Monkey alcohol tissue research resource: banking tissues for alcohol research. Alcoholism, Clinical and Experimental Research. 38: 1973-81. PMID 24942558 DOI: 10.1111/acer.12467  1
2014 Pattison LP, McIntosh S, Sexton T, Childers SR, Hemby SE. Changes in dopamine transporter binding in nucleus accumbens following chronic self-administration cocaine: heroin combinations. Synapse (New York, N.Y.). 68: 437-44. PMID 24916769 DOI: 10.1002/syn.21755  1
2014 Burnett EJ, Grant KA, Davenport AT, Hemby SE, Friedman DP. The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys. Drug and Alcohol Dependence. 136: 135-42. PMID 24467872 DOI: 10.1016/j.drugalcdep.2014.01.002  1
2014 Willard SL, Hemby SE, Register TC, McIntosh S, Shively CA. Altered expression of glial and synaptic markers in the anterior hippocampus of behaviorally depressed female monkeys. Neuroscience Letters. 563: 1-5. PMID 24440617 DOI: 10.1016/j.neulet.2014.01.012  1
2014 Bough KJ, Amur S, Lao G, Hemby SE, Tannu NS, Kampman KM, Schmitz JM, Martinez D, Merchant KM, Green C, Sharma J, Dougherty AH, Moeller FG. Biomarkers for the development of new medications for cocaine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 202-19. PMID 23979119 DOI: 10.1038/npp.2013.210  1
2013 McIntosh S, Howell L, Hemby SE. Dopaminergic dysregulation in prefrontal cortex of rhesus monkeys following cocaine self-administration. Frontiers in Psychiatry. 4: 88. PMID 23970867 DOI: 10.3389/fpsyt.2013.00088  1
2013 Chen J, Repunte-Canonigo V, Kawamura T, Lefebvre C, Shin W, Howell LL, Hemby SE, Harvey BK, Califano A, Morales M, Koob GF, Sanna PP. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Nature Communications. 4: 1955. PMID 23736082 DOI: 10.1038/ncomms2955  1
2012 Pattison LP, McIntosh S, Budygin EA, Hemby SE. Differential regulation of accumbal dopamine transmission in rats following cocaine, heroin and speedball self-administration. Journal of Neurochemistry. 122: 138-46. PMID 22443145 DOI: 10.1111/j.1471-4159.2012.07738.x  1
2012 Ginsberg SD, Hemby SE, Smiley JF. Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. Pharmacology, Biochemistry, and Behavior. 100: 705-11. PMID 22005598 DOI: 10.1016/j.pbb.2011.09.015  1
2011 Acosta G, Freidman DP, Grant KA, Hemby SE. Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Frontiers in Psychiatry. 2: 72. PMID 22291662 DOI: 10.3389/fpsyt.2011.00072  1
2011 Pattison LP, Bonin KD, Hemby SE, Budygin EA. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. 60: 312-7. PMID 20869972 DOI: 10.1016/j.neuropharm.2010.09.014  1
2010 Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biological Psychiatry. 68: 774-7. PMID 20692647 DOI: 10.1016/j.biopsych.2010.06.022  1
2010 Abdolahi A, Acosta G, Breslin FJ, Hemby SE, Lynch WJ. Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex. The European Journal of Neuroscience. 31: 733-41. PMID 20384816 DOI: 10.1111/j.1460-9568.2010.07114.x  1
2010 Hemby SE. Cocainomics: new insights into the molecular basis of cocaine addiction. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 70-82. PMID 20084466 DOI: 10.1007/s11481-009-9189-8  1
2010 Acosta G, Hasenkamp W, Daunais JB, Friedman DP, Grant KA, Hemby SE. Ethanol self-administration modulation of NMDA receptor subunit and related synaptic protein mRNA expression in prefrontal cortical fields in cynomolgus monkeys. Brain Research. 1318: 144-54. PMID 20043891 DOI: 10.1016/j.brainres.2009.12.050  1
2010 Daunais JB, Kraft RA, Davenport AT, Burnett EJ, Maxey VM, Szeliga KT, Rau AR, Flory GS, Hemby SE, Kroenke CD, Grant KA, Friedman DP. MRI-guided dissection of the nonhuman primate brain: a case study. Methods (San Diego, Calif.). 50: 199-204. PMID 19364532 DOI: 10.1016/j.ymeth.2009.03.023  1
2010 Tannu NS, Howell LL, Hemby SE. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular Psychiatry. 15: 185-203. PMID 18504425 DOI: 10.1038/mp.2008.53  1
2009 Hemby SE, Tannu N. Modeling substance abuse for applications in proteomics. Methods in Molecular Biology (Clifton, N.J.). 566: 69-83. PMID 20058165 DOI: 10.1007/978-1-59745-562-6_5  1
2008 Backes EN, Hemby SE. Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. Neurochemical Research. 33: 459-67. PMID 17943439 DOI: 10.1007/s11064-007-9454-2  1
2007 O'Connor JA, Hemby SE. Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia. Schizophrenia Research. 97: 277-88. PMID 17942280 DOI: 10.1016/j.schres.2007.09.022  1
2007 Tannu NS, Hemby SE. De novo protein sequence analysis of Macaca mulatta. Bmc Genomics. 8: 270. PMID 17686166 DOI: 10.1186/1471-2164-8-270  1
2007 O'Connor JA, Muly EC, Arnold SE, Hemby SE. AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs. Schizophrenia Research. 90: 28-40. PMID 17141476 DOI: 10.1016/j.schres.2006.10.004  1
2007 Tannu N, Mash DC, Hemby SE. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular Psychiatry. 12: 55-73. PMID 17075605 DOI: 10.1038/  1
2007 Hemby SE, O'Connor JA. Transcriptional Regulation in Schizophrenia Adolescent Psychopathology and the Developing Brain: Integrating Brain and Prevention Science. DOI: 10.1093/acprof:oso/9780195306255.003.0005  1
2006 Tannu NS, Hemby SE. Two-dimensional fluorescence difference gel electrophoresis for comparative proteomics profiling. Nature Protocols. 1: 1732-42. PMID 17487156 DOI: 10.1038/nprot.2006.256  1
2006 Hemby SE, O'connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA-A subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcoholism, Clinical and Experimental Research. 30: 1978-85. PMID 17117962 DOI: 10.1111/j.1530-0277.2006.00254.x  1
2006 Hemby SE. Assessment of genome and proteome profiles in cocaine abuse. Progress in Brain Research. 158: 173-95. PMID 17027697 DOI: 10.1016/S0079-6123(06)58009-4  1
2006 Tannu NS, Hemby SE. Methods for proteomics in neuroscience. Progress in Brain Research. 158: 41-82. PMID 17027691 DOI: 10.1016/S0079-6123(06)58003-3  1
2006 O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE. Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration. Biological Psychiatry. 60: 659-62. PMID 16806093 DOI: 10.1016/j.biopsych.2006.03.044  1
2006 Tannu N, Hemby SE. Quantitation in two-dimensional fluorescence difference gel electrophoresis: effect of protein fixation. Electrophoresis. 27: 2011-5. PMID 16607608 DOI: 10.1002/elps.200500710  1
2006 O'Connor J, Muly EC, Hemby SE. Molecular mapping of striatal subdivisions in juvenile Macaca Mulata. Experimental Neurology. 198: 326-37. PMID 16455077 DOI: 10.1016/j.expneurol.2005.11.028  1
2006 Smith JE, Co C, Coller MD, Hemby SE, Martin TJ. Self-administered heroin and cocaine combinations in the rat: additive reinforcing effects-supra-additive effects on nucleus accumbens extracellular dopamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 139-50. PMID 15956989 DOI: 10.1038/sj.npp.1300786  1
2006 Ginsberg SD, Hemby SE, Mufson EJ, Martin LJ. Cell and tissue microdissection in combination with genomic and proteomic applications Neuroanatomical Tract-Tracing 3: Molecules, Neurons, and Systems. 109-141. DOI: 10.1007/0-387-28942-9_4  1
2005 Hemby SE, Tang W, Muly EC, Kuhar MJ, Howell L, Mash DC. Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of Neurochemistry. 95: 1785-93. PMID 16363995 DOI: 10.1111/j.1471-4159.2005.03517.x  1
2005 Hemby SE, Horman B, Tang W. Differential regulation of ionotropic glutamate receptor subunits following cocaine self-administration. Brain Research. 1064: 75-82. PMID 16277980 DOI: 10.1016/j.brainres.2005.09.051  1
2004 Verkuyl JM, Hemby SE, Joëls M. Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus. The European Journal of Neuroscience. 20: 1665-73. PMID 15355334 DOI: 10.1111/j.1460-9568.2004.03568.x  1
2004 Hemby SE. Morphine-induced alterations in gene expression of calbindin immunopositive neurons in nucleus accumbens shell and core. Neuroscience. 126: 689-703. PMID 15183518 DOI: 10.1016/j.neuroscience.2004.01.056  1
2004 Freeman WM, Hemby SE. Proteomics for protein expression profiling in neuroscience. Neurochemical Research. 29: 1065-81. PMID 15176464 DOI: 10.1023/B:NERE.0000023594.21352.17  1
2004 Ginsberg SD, Elarova I, Ruben M, Tan F, Counts SE, Eberwine JH, Trojanowski JQ, Hemby SE, Mufson EJ, Che S. Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Neurochemical Research. 29: 1053-64. PMID 15176463 DOI: 10.1023/B:NERE.0000023593.77052.f7  1
2004 Tang W, Wesley M, Freeman WM, Liang B, Hemby SE. Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats. Journal of Neurochemistry. 89: 1021-33. PMID 15140200 DOI: 10.1111/j.1471-4159.2004.02392.x  1
2003 Fasulo WH, Hemby SE. Time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. Journal of Neurochemistry. 87: 205-19. PMID 12969267 DOI: 10.1046/j.1471-4159.2003.01986.x  1
2003 Backes E, Hemby SE. Discrete cell gene profiling of ventral tegmental dopamine neurons after acute and chronic cocaine self-administration. The Journal of Pharmacology and Experimental Therapeutics. 307: 450-9. PMID 12966149 DOI: 10.1124/jpet.103.054965  1
2003 Tang WX, Fasulo WH, Mash DC, Hemby SE. Molecular profiling of midbrain dopamine regions in cocaine overdose victims. Journal of Neurochemistry. 85: 911-24. PMID 12716423  1
2003 Hemby SE, Trojanowski JQ, Ginsberg SD. Neuron-specific age-related decreases in dopamine receptor subtype mRNAs. The Journal of Comparative Neurology. 456: 176-83. PMID 12509874 DOI: 10.1002/cne.10525  1
2002 Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation Cell. 111: 837-851. PMID 12526810 DOI: 10.1016/S0092-8674(02)01139-X  1
2002 Hasenkamp W, Hemby SE. Functional genomics and psychiatric illness. Progress in Brain Research. 138: 375-93. PMID 12432779 DOI: 10.1016/S0079-6123(02)38087-7  1
2002 Hemby SE, Ginsberg SD, Brunk B, Arnold SE, Trojanowski JQ, Eberwine JH. Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Archives of General Psychiatry. 59: 631-40. PMID 12090816  1
2001 Hemby SE, Sanchez MM, Winslow JT. Functional genomics approaches to a primate model of autistic symptomology. Journal of Autism and Developmental Disorders. 31: 551-5. PMID 11814265 DOI: 10.1023/A:1013286725596  1
2000 Ginsberg SD, Hemby SE, Lee VM, Eberwine JH, Trojanowski JQ. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Annals of Neurology. 48: 77-87. PMID 10894219 DOI: 10.1002/1531-8249(200007)48:1<77::AID-ANA12>3.0.CO;2-A  1
1999 Hemby SE. Recent advances in the biology of addiction. Current Psychiatry Reports. 1: 159-65. PMID 11122919  1
1999 Ginsberg SD, Crino PB, Hemby SE, Weingarten JA, Lee VM, Eberwine JH, Trojanowski JQ. Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques. Annals of Neurology. 45: 174-81. PMID 9989619 DOI: 10.1002/1531-8249(199902)45:2<174::AID-ANA7>3.0.CO;2-E  1
1999 Hemby SE, Co C, Dworkin SI, Smith JE. Synergistic elevations in nucleus accumbens extracellular dopamine concentrations during self-administration of cocaine/heroin combinations (Speedball) in rats. The Journal of Pharmacology and Experimental Therapeutics. 288: 274-80. PMID 9862781  1
1998 Crino P, Khodakhah K, Becker K, Ginsberg S, Hemby S, Eberwine J. Presence and phosphorylation of transcription factors in developing dendrites. Proceedings of the National Academy of Sciences of the United States of America. 95: 2313-8. PMID 9482882 DOI: 10.1073/pnas.95.5.2313  1
1997 Hemby SE, Co C, Koves TR, Smith JE, Dworkin SI. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology. 133: 7-16. PMID 9335075 DOI: 10.1007/s002130050365  1
1997 Hemby SE, Lucki I, Gatto G, Singh A, Thornley C, Matasi J, Kong N, Smith JE, Davies HM, Dworkin SI. Potential antidepressant effects of novel tropane compounds, selective for serotonin or dopamine transporters. The Journal of Pharmacology and Experimental Therapeutics. 282: 727-33. PMID 9262336  1
1996 Hemby SE, Smith JE, Dworkin SI. The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats. The Journal of Pharmacology and Experimental Therapeutics. 277: 1247-58. PMID 8667185  1
1996 Crino P, Hemby S, Eberwine J. Utility of in situ transcription, single-cell nucleic acid amplification and expression profiling in the study of the central nervous system development Cell Vision - Journal of Analytical Morphology. 3: 203-206.  1
1995 Hemby SE, Co C, Reboussin D, Davies HM, Dworkin SI, Smith JE. Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. The Journal of Pharmacology and Experimental Therapeutics. 273: 656-66. PMID 7752068  1
1995 Hemby SE, Martin TJ, Co C, Dworkin SI, Smith JE. The effects of intravenous heroin administration on extracellular nucleus accumbens dopamine concentrations as determined by in vivo microdialysis. The Journal of Pharmacology and Experimental Therapeutics. 273: 591-8. PMID 7752060  1
1994 Hemby SE, Jones GH, Hubert GW, Neill DB, Justice JB. Assessment of the relative contribution of peripheral and central components in cocaine place conditioning. Pharmacology, Biochemistry, and Behavior. 47: 973-9. PMID 8029272 DOI: 10.1016/0091-3057(94)90306-9  1
1993 Hooks MS, Jones GH, Hemby SE, Justice JB. Environmental and pharmacological sensitization: effects of repeated administration of systemic or intra-nucleus accumbens cocaine. Psychopharmacology. 111: 109-16. PMID 7870925 DOI: 10.1007/BF02257416  1
1992 Hemby SE, Jones GH, Justice JB, Neill DB. Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine. Psychopharmacology. 106: 330-6. PMID 1570378 DOI: 10.1007/BF02245413  1
1992 Hemby SE, Jones GH, Neill DB, Justice JB. 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence cocaine-induced place conditioning. Behavioural Brain Research. 49: 225-30. PMID 1388816 DOI: 10.1016/S0166-4328(05)80168-8  1
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