John M. Harrold, Ph.D. - Publications

Affiliations: 
2005 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Chemical Engineering

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Harrold J, Gisleskog PO, Perez-Ruixo JJ, Delor I, Chow A, Jacqmin P, Melhem M. Prediction of survival benefit of filgrastim in adult and pediatric patients with acute radiation syndrome. Clinical and Translational Science. PMID 32112517 DOI: 10.1111/Cts.12777  0.346
2020 Belmontes B, Tan H, Zhong W, Chui D, Cook K, O'Brien S, Martin M, Alexander B, Eng J, Harrold J, Aeffner F, Chun M, Bakker A, Balazs M, DeVoss J, et al. Abstract PR12: Assessing in vivo mechanisms regulating the therapeutic activity of bi-specific T-cell engager (BiTE®) molecules in immunocompetent mice expressing a chimeric human/mouse CD3ε receptor Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Pr12  0.327
2018 Melhem M, Delor I, Pérez-Ruixo JJ, Harrold J, Chow A, Wu L, Jacqmin P. Pharmacokinetic-pharmacodynamic modelling of neutrophil response to G-CSF in healthy subjects and patients with chemotherapy-induced neutropenia. British Journal of Clinical Pharmacology. PMID 29318653 DOI: 10.1111/Bcp.13504  0.343
2016 Krzyzanski W, Harrold JM, Wu LS, Perez-Ruixo JJ. A cell-level model of pharmacodynamics-mediated drug disposition. Journal of Pharmacokinetics and Pharmacodynamics. PMID 27612462 DOI: 10.1007/S10928-016-9491-Z  0.455
2015 Krzyzanski W, Perez-Ruixo JJ, Harrold J. Pharmacodynamic model for chemoradiotherapy-induced thrombocytopenia in mice Journal of Pharmacokinetics and Pharmacodynamics. 42: 709-720. PMID 26341875 DOI: 10.1007/S10928-015-9440-2  0.382
2015 Chudasama VL, Zutshi A, Singh P, Abraham AK, Mager DE, Harrold JM. Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies. Journal of Pharmacokinetics and Pharmacodynamics. 42: 1-18. PMID 25559227 DOI: 10.1007/S10928-014-9401-1  0.365
2014 Harrold JM, Abraham AK. Ubiquity: a framework for physiological/mechanism-based pharmacokinetic/pharmacodynamic model development and deployment. Journal of Pharmacokinetics and Pharmacodynamics. 41: 141-51. PMID 24619141 DOI: 10.1007/S10928-014-9352-6  0.329
2014 Harrold J, Jacqmin P, Olsson P, Delor I, Morrow PK, Yang B, Chow A, Perez-Ruixo JJ. Translational Modeling to Identify Human Dosing of Filgrastim to Improve Overall Survival (OS) in Acute Radiation Syndrome (ARS) Blood. 124: 690-690. DOI: 10.1182/Blood.V124.21.690.690  0.344
2013 Harrold JM, Ramanathan M, Mager DE. Network-based approaches in drug discovery and early development. Clinical Pharmacology and Therapeutics. 94: 651-8. PMID 24025802 DOI: 10.1038/Clpt.2013.176  0.339
2012 Chudasama VL, Schaedeli Stark F, Harrold JM, Tibbitts J, Girish SR, Gupta M, Frey N, Mager DE. Semi-mechanistic population pharmacokinetic model of multivalent trastuzumab emtansine in patients with metastatic breast cancer. Clinical Pharmacology and Therapeutics. 92: 520-7. PMID 22968044 DOI: 10.1038/Clpt.2012.153  0.354
2012 Vugmeyster Y, Harrold J, Xu X. Absorption, distribution, metabolism, and excretion (ADME) studies of biotherapeutics for autoimmune and inflammatory conditions. Aaps Journal. 14: 714-727. PMID 22798020 DOI: 10.1208/S12248-012-9385-Y  0.388
2012 Harrold JM, Straubinger RM, Mager DE. Combinatorial chemotherapeutic efficacy in non-Hodgkin lymphoma can be predicted by a signaling model of CD20 pharmacodynamics. Cancer Research. 72: 1632-41. PMID 22350416 DOI: 10.1158/0008-5472.Can-11-2432  0.381
2010 Kagan L, Abraham AK, Harrold JM, Mager DE. Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons. Pharmaceutical Research. 27: 920-32. PMID 20232116 DOI: 10.1007/S11095-010-0098-6  0.361
2010 Zhou R, Mazurchuk RV, Tamburlin JH, Harrold JM, Mager DE, Straubinger RM. Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model. The Journal of Pharmacology and Experimental Therapeutics. 332: 479-88. PMID 19861574 DOI: 10.1124/Jpet.109.160044  0.325
2009 Harrold JM, Parker RS. Clinically relevant cancer chemotherapy dose scheduling via mixed-integer optimization Computers & Chemical Engineering. 33: 2042-2054. DOI: 10.1016/J.Compchemeng.2009.06.005  0.509
2005 Harrold JM, Eiseman JL, Joseph E, Strychor S, Zamboni WC, Parker RS. Control-relevant modeling of the antitumor effects of 9-nitrocamptothecin in SCID mice bearing HT29 human colon xenografts. Journal of Pharmacokinetics and Pharmacodynamics. 32: 65-83. PMID 16205839 DOI: 10.1007/S10928-005-2103-Y  0.533
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