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Stephen D. Meriney - Publications

University of Pittsburgh, Pittsburgh, PA, United States 
Regulation and modulation of presynaptic ion channels and transmitter release

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Laghaei R, Meriney SD. Microphysiological Modeling of the Structure and Function of Neuromuscular Transmitter Release Sites. Frontiers in Synaptic Neuroscience. 14: 917285. PMID 35769072 DOI: 10.3389/fnsyn.2022.917285  0.444
2022 Ginebaugh SP, Badawi Y, Tarr TB, Meriney SD. Neuromuscular Active Zone Structure and Function in Healthy and Lambert-Eaton Myasthenic Syndrome States. Biomolecules. 12. PMID 35740866 DOI: 10.3390/biom12060740  0.841
2021 Ojala KS, Ginebaugh SP, Wu M, Miller EW, Ortiz G, Covarrubias M, Meriney SD. A high affinity, partial antagonist effect of 3,4-diaminopyridine mediates action potential broadening and enhancement of transmitter release at NMJs. The Journal of Biological Chemistry. 100302. PMID 33465376 DOI: 10.1016/j.jbc.2021.100302  0.459
2020 Ginebaugh SP, Cyphers ED, Lanka V, Ortiz G, Miller EW, Laghaei R, Meriney SD. The frog motor nerve terminal has very brief action potentials and three electrical regions predicted to differentially control transmitter release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32265260 DOI: 10.1523/Jneurosci.2415-19.2020  0.448
2018 Meriney SD, Lacomis D. Reported direct aminopyridine effects on voltage-gated calcium channels is a high-dose pharmacological off-target effect of no clinical relevance. The Journal of Biological Chemistry. 293: 16100. PMID 30315087 DOI: 10.1074/Jbc.L118.005425  0.454
2018 Dittrich M, Homan AE, Meriney SD. Presynaptic mechanisms controlling calcium-triggered transmitter release at the neuromuscular junction. Current Opinion in Physiology. 4: 15-24. PMID 30272045 DOI: 10.1016/j.cophys.2018.03.004  0.562
2018 Homan AE, Meriney SD. Active zone structure-function relationships at the neuromuscular junction. Synapse (New York, N.Y.). PMID 29956366 DOI: 10.1002/syn.22057  0.533
2017 Laghaei R, Ma J, Tarr T, Homan AE, Kelly L, Tilvawala M, Vuocolo B, Rajasekaran H, Meriney SD, Dittrich M. Transmitter release site organization can predict synaptic function at the neuromuscular junction. Journal of Neurophysiology. PMID 29357458 DOI: 10.1152/jn.00168.2017  0.807
2017 Wu M, White HV, Boehm B, Meriney CJ, Kerrigan K, Frasso M, Liang M, Gotway EM, Wilcox M, Johnson JW, Wipf P, Meriney SD. New Cav2 calcium channel gating modifiers with agonist activity and therapeutic potential to treat neuromuscular disease. Neuropharmacology. PMID 29246857 DOI: 10.1016/J.Neuropharm.2017.12.022  0.599
2017 Homan AE, Laghaei R, Dittrich M, Meriney SD. The impact of spatio-temporal calcium dynamics within presynaptic active zones on synaptic delay at the frog neuromuscular junction. Journal of Neurophysiology. jn.00510.2017. PMID 29167324 DOI: 10.1152/jn.00510.2017  0.543
2017 Meriney SD, Tarr TB, Ojala KS, Wu M, Li Y, Lacomis D, Garcia-Ocaña A, Liang M, Valdomir G, Wipf P. Lambert-Eaton myasthenic syndrome: mouse passive-transfer model illuminates disease pathology and facilitates testing therapeutic leads. Annals of the New York Academy of Sciences. PMID 29125190 DOI: 10.1111/Nyas.13512  0.848
2015 Dittrich M, Meriney SD. Single Calcium Channels Stand Out In The Crowd. Channels (Austin, Tex.). 0. PMID 26689237 DOI: 10.1080/19336950.2015.1119633  0.496
2015 Luo F, Dittrich M, Cho S, Stiles JR, Meriney SD. Transmitter release is evoked with low probability predominately by calcium flux through single channel openings at the frog neuromuscular junction. Journal of Neurophysiology. 113: 2480-9. PMID 25652927 DOI: 10.1152/jn.00879.2014  0.758
2015 Ma J, Kelly L, Ingram J, Price TJ, Meriney SD, Dittrich M. New insights into short-term synaptic facilitation at the frog neuromuscular junction. Journal of Neurophysiology. 113: 71-87. PMID 25210157 DOI: 10.1152/jn.00198.2014  0.503
2014 Tarr TB, Wipf P, Meriney SD. Synaptic Pathophysiology and Treatment of Lambert-Eaton Myasthenic Syndrome. Molecular Neurobiology. PMID 25195700 DOI: 10.1007/S12035-014-8887-2  0.814
2014 Meriney SD, Umbach JA, Gundersen CB. Fast, Ca2+-dependent exocytosis at nerve terminals: shortcomings of SNARE-based models. Progress in Neurobiology. 121: 55-90. PMID 25042638 DOI: 10.1016/j.pneurobio.2014.07.001  0.495
2014 Tarr TB, Lacomis D, Reddel SW, Liang M, Valdomir G, Frasso M, Wipf P, Meriney SD. Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist. The Journal of Physiology. 592: 3687-96. PMID 25015919 DOI: 10.1113/Jphysiol.2014.276493  0.83
2013 Dittrich M, Pattillo JM, King JD, Cho S, Stiles JR, Meriney SD. An excess-calcium-binding-site model predicts neurotransmitter release at the neuromuscular junction. Biophysical Journal. 104: 2751-63. PMID 23790384 DOI: 10.1016/J.Bpj.2013.05.023  0.798
2013 Tarr TB, Malick W, Liang M, Valdomir G, Frasso M, Lacomis D, Reddel SW, Garcia-Ocano A, Wipf P, Meriney SD. Evaluation of a novel calcium channel agonist for therapeutic potential in Lambert-Eaton myasthenic syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10559-67. PMID 23785168 DOI: 10.1523/Jneurosci.4629-12.2013  0.826
2013 Meriney SD, Dittrich M. Organization and function of transmitter release sites at the neuromuscular junction. The Journal of Physiology. 591: 3159-65. PMID 23613535 DOI: 10.1113/jphysiol.2012.248625  0.578
2013 Tarr TB, Dittrich M, Meriney SD. Are unreliable release mechanisms conserved from NMJ to CNS? Trends in Neurosciences. 36: 14-22. PMID 23102681 DOI: 10.1016/j.tins.2012.09.009  0.852
2012 Liang M, Tarr TB, Bravo-Altamirano K, Valdomir G, Rensch G, Swanson L, DeStefino NR, Mazzarisi CM, Olszewski RA, Wilson GM, Meriney SD, Wipf P. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. Acs Medicinal Chemistry Letters. 3: 985-90. PMID 24936234 DOI: 10.1021/Ml3002083  0.815
2012 Tarr TB, Valdomir G, Liang M, Wipf P, Meriney SD. New calcium channel agonists as potential therapeutics in Lambert-Eaton myasthenic syndrome and other neuromuscular diseases. Annals of the New York Academy of Sciences. 1275: 85-91. PMID 23278582 DOI: 10.1111/Nyas.12001  0.847
2012 Burton SD, Johnson JW, Zeringue HC, Meriney SD. Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures. Neuroscience. 215: 1-16. PMID 22542674 DOI: 10.1016/J.Neuroscience.2012.04.047  0.392
2011 Luo F, Dittrich M, Stiles JR, Meriney SD. Single-pixel optical fluctuation analysis of calcium channel function in active zones of motor nerve terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11268-81. PMID 21813687 DOI: 10.1523/JNEUROSCI.1394-11.2011  0.736
2011 Cosgrove KE, Galván EJ, Barrionuevo G, Meriney SD. mGluRs modulate strength and timing of excitatory transmission in hippocampal area CA3. Molecular Neurobiology. 44: 93-101. PMID 21559753 DOI: 10.1007/S12035-011-8187-Z  0.786
2011 Douthitt HL, Luo F, McCann SD, Meriney SD. Dynasore, an inhibitor of dynamin, increases the probability of transmitter release. Neuroscience. 172: 187-95. PMID 21056636 DOI: 10.1016/j.neuroscience.2010.10.002  0.505
2011 Cosgrove KE, Meriney SD, Barrionuevo G. High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons. Hippocampus. 21: 1302-17. PMID 20824730 DOI: 10.1002/Hipo.20842  0.793
2010 Meunier FA, Nguyen TH, Colasante C, Luo F, Sullivan RK, Lavidis NA, Molgó J, Meriney SD, Schiavo G. Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin. Journal of Cell Science. 123: 1131-40. PMID 20215402 DOI: 10.1242/Jcs.049296  0.666
2010 DeStefino NR, Pilato AA, Dittrich M, Cherry SV, Cho S, Stiles JR, Meriney SD. (R)-roscovitine prolongs the mean open time of unitary N-type calcium channel currents. Neuroscience. 167: 838-49. PMID 20188151 DOI: 10.1016/j.neuroscience.2010.02.041  0.54
2010 Galván EJ, Cosgrove KE, Mauna JC, Card JP, Thiels E, Meriney SD, Barrionuevo G. Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2844-55. PMID 20181582 DOI: 10.1523/Jneurosci.5269-09.2010  0.792
2010 Cosgrove KE, Galván EJ, Meriney SD, Barrionuevo G. Area CA3 interneurons receive two spatially segregated mossy fiber inputs. Hippocampus. 20: 1003-9. PMID 19830814 DOI: 10.1002/Hipo.20713  0.775
2007 Keith RK, Poage RE, Yokoyama CT, Catterall WA, Meriney SD. Bidirectional modulation of transmitter release by calcium channel/syntaxin interactions in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 265-9. PMID 17215385 DOI: 10.1523/Jneurosci.4213-06.2007  0.836
2006 Cho S, Meriney SD. The effects of presynaptic calcium channel modulation by roscovitine on transmitter release at the adult frog neuromuscular junction. The European Journal of Neuroscience. 23: 3200-8. PMID 16820010 DOI: 10.1111/j.1460-9568.2006.04849.x  0.606
2005 King JD, Meriney SD. Proportion of N-type calcium current activated by action potential stimuli. Journal of Neurophysiology. 94: 3762-70. PMID 16107524 DOI: 10.1152/jn.01289.2004  0.555
2004 Wachman ES, Poage RE, Stiles JR, Farkas DL, Meriney SD. Spatial Distribution of Calcium Entry Evoked by Single Action Potentials within the Presynaptic Active Zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2877-85. PMID 15044526 DOI: 10.1523/JNEUROSCI.1660-03.2004  0.822
2002 Poage RE, Meriney SD. Presynaptic calcium influx, neurotransmitter release, and neuromuscular disease. Physiology & Behavior. 77: 507-12. PMID 12526991 DOI: 10.1016/S0031-9384(02)00937-X  0.815
2001 Pattillo JM, Yazejian B, DiGregorio DA, Vergara JL, Grinnell AD, Meriney SD. Contribution of presynaptic calcium-activated potassium currents to transmitter release regulation in cultured Xenopus nerve-muscle synapses. Neuroscience. 102: 229-40. PMID 11226687 DOI: 10.1016/S0306-4522(00)00453-X  0.844
2000 Artim DE, Meriney SD. G-protein-modulated Ca(2+) current with slowed activation does not alter the kinetics of action potential-evoked Ca(2+) current. Journal of Neurophysiology. 84: 2417-25. PMID 11067984 DOI: 10.1152/Jn.2000.84.5.2417  0.843
1999 Poage RE, Meriney SD, Gundersen CB, Umbach JA. Antibodies against cysteine string proteins inhibit evoked neurotransmitter release at Xenopus neuromuscular junctions. Journal of Neurophysiology. 82: 50-9. PMID 10400934 DOI: 10.1152/JN.1999.82.1.50  0.776
1999 Gray DB, Polo-Parada L, Pilar GR, Eang P, Metzger RR, Klann E, Meriney SD. A nitric oxide/cyclic GMP-dependent protein kinase pathway alters transmitter release and inhibition by somatostatin at a site downstream of calcium entry. Journal of Neurochemistry. 72: 1981-90. PMID 10217275 DOI: 10.1046/j.1471-4159.1999.0721981.x  0.743
1999 Pattillo JM, Artim DE, Simples JE, Meriney SD. Variations in onset of action potential broadening: effects on calcium current studied in chick ciliary ganglion neurones. The Journal of Physiology. 514: 719-28. PMID 9882744 DOI: 10.1111/J.1469-7793.1999.719Ad.X  0.753
1997 White MG, Crumling MA, Meriney SD. Developmental changes in calcium current pharmacology and somatostatin inhibition in chick parasympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6302-13. PMID 9236240 DOI: 10.1523/Jneurosci.17-16-06302.1997  0.61
1997 Yazejian B, DiGregorio DA, Vergara JL, Poage RE, Meriney SD, Grinnell AD. Direct measurements of presynaptic calcium and calcium-activated potassium currents regulating neurotransmitter release at cultured Xenopus nerve-muscle synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2990-3001. PMID 9096135 DOI: 10.1523/Jneurosci.17-09-02990.1997  0.764
1997 Yazejian B, DiGregorio DA, Vergara JL, Poage RE, Meriney SD, Grinnell AD. Direct Measurements of Presynaptic Calcium and Calcium-Activated Potassium Currents Regulating Neurotransmitter Release at CulturedXenopusNerve–Muscle Synapses The Journal of Neuroscience. 17: 2990-3001. DOI: 10.1523/JNEUROSCI.17-09-02990.1997  0.828
1996 Meriney SD, Wolowske B, Ezzati E, Grinnell AD. Low calcium-induced disruption of active zone structure and function at the frog neuromuscular junction. Synapse (New York, N.Y.). 24: 1-11. PMID 9046071 DOI: 10.1002/(SICI)1098-2396(199609)24:1<1::AID-SYN1>3.0.CO;2-A  0.745
1996 Meriney SD, Hulsizer SC, Lennon VA, Grinnell AD. Lambert-Eaton myasthenic syndrome immunoglobulins react with multiple types of calcium channels in small-cell lung carcinoma. Annals of Neurology. 40: 739-49. PMID 8957015 DOI: 10.1002/ana.410400510  0.712
1996 Pilar G, Gray DB, Meriney SD. Membrane delimited and intracellular soluble pathways in the somatostatin modulation of ACh release. Life Sciences. 58: 1979-86. PMID 8637427 DOI: 10.1016/0024-3205(96)00188-9  0.715
1994 Meriney SD, Gray DB, Pilar GR. Somatostatin-induced inhibition of neuronal Ca2+ current modulated by cGMP-dependent protein kinase. Nature. 369: 336-9. PMID 7910377 DOI: 10.1038/369336a0  0.737
1991 Meriney SD, Grinnell AD. Endogenous adenosine modulates stimulation-induced depression at the frog neuromuscular junction. The Journal of Physiology. 443: 441-55. PMID 1688026 DOI: 10.1113/Jphysiol.1991.Sp018843  0.636
1991 Meriney SD, Ford MJ, Oliva D, Pilar G. Endogenous opioids modulate neuronal survival in the developing avian ciliary ganglion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3705-17. PMID 1660533  0.603
1991 Hulsizer SC, Meriney SD, Grinnell AD. Calcium currents in presynaptic varicosities of embryonic motoneurons. Annals of the New York Academy of Sciences. 635: 424-8. PMID 1660245 DOI: 10.1111/J.1749-6632.1991.Tb36516.X  0.698
1991 Meriney SD, Hulsizer SC, Grinell AD. Calcium currents in varicosities of motoneuron neurites ending on muscle cells in vitro Biomedical Research. 12: 53-55.  0.329
1989 Meriney SD, Young SH, Grinnell AD. Constraints on the interpretation of nonquantal acetylcholine release from frog neuromuscular junctions. Proceedings of the National Academy of Sciences of the United States of America. 86: 2098-102. PMID 2784566 DOI: 10.1073/Pnas.86.6.2098  0.649
1989 Grinnell AD, Gundersen CB, Meriney SD, Young SH. Direct measurement of ACh release from exposed frog nerve terminals: constraints on interpretation of non-quantal release. The Journal of Physiology. 419: 225-51. PMID 2621630 DOI: 10.1113/jphysiol.1989.sp017871  0.685
1988 Pilar G, Freyer HJ, Meriney SD, Ford MJ. The regulation of neuronal number during embryonic chick development. Puerto Rico Health Sciences Journal. 7: 149-55. PMID 2847211  0.546
1987 Meriney SD, Pilar G. Cholinergic innervation of the smooth muscle cells in the choroid coat of the chick eye and its development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3827-39. PMID 3694256  0.604
1987 Meriney SD, Pilar G, Ogawa M, Nunez R. Differential neuronal survival in the avian ciliary ganglion after chronic acetylcholine receptor blockade. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3840-9. PMID 2826719  0.578
1987 Pilar G, Nuñez R, McLennan IS, Meriney SD. Muscarinic and nicotinic synaptic activation of the developing chicken iris. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3813-26. PMID 2826718  0.623
1985 Meriney SD, Gray DB, Pilar G. Morphine-induced delay of normal cell death in the avian ciliary ganglion. Science (New York, N.Y.). 228: 1451-3. PMID 2990029 DOI: 10.1126/Science.2990029  0.608
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