Marcus B. Smolka, PhD - Publications

Cornell University, Ithaca, NY, United States 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Joiner AM, Phillips BP, Yugandhar K, Sanford EJ, Smolka MB, Yu H, Miller EA, Fromme JC. Structural basis of TRAPPIII-mediated Rab1 activation. The Embo Journal. e107607. PMID 34018207 DOI: 10.15252/embj.2020107607  1
2021 Pellicanò G, Al Mamun M, Jurado-Santiago D, Villa-Hernández S, Yin X, Giannattasio M, Lanz MC, Smolka MB, Yeeles J, Shirahige K, García-Díaz M, Bermejo R. Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse. Molecular Cell. PMID 33932350 DOI: 10.1016/j.molcel.2021.04.006  0.01
2021 Sanford EJ, Comstock WJ, Faça VM, Vega SC, Gnügge R, Symington LS, Smolka MB. Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper-resection. The Embo Journal. e104566. PMID 33764556 DOI: 10.15252/embj.2020104566  0.04
2021 Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB. In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. Embo Reports. e51121. PMID 33491328 DOI: 10.15252/embr.202051121  1
2020 Yugandhar K, Wang TY, Leung AK, Lanz MC, Motorykin I, Liang J, Shayhidin EE, Smolka MB, Zhang S, Yu H. MaXLinker: Proteome-wide Cross-link Identifications with High Specificity and Sensitivity. Molecular & Cellular Proteomics : McP. 19: 554-568. PMID 33451689 DOI: 10.1074/mcp.TIR119.001847  1
2020 Faca VM, Sanford EJ, Tieu J, Comstock W, Gupta S, Marshall S, Yu H, Smolka MB. Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network. Scientific Reports. 10: 18056. PMID 33093574 DOI: 10.1038/s41598-020-74939-4  1
2020 Bruhn C, Ajazi A, Ferrari E, Lanz MC, Batrin R, Choudhary R, Walvekar A, Laxman S, Longhese MP, Fabre E, Smolka MB, Foiani M. The Rad53-Spt21 and Tel1 axes couple glucose tolerance to histone dosage and subtelomeric silencing. Nature Communications. 11: 4154. PMID 32814778 DOI: 10.1038/S41467-020-17961-4  0.01
2020 Dibitetto D, Sims JR, Ascenção CFR, Feng K, Kim D, Oberly S, Freire R, Smolka MB. Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling. Nar Cancer. 2: zcaa006. PMID 32743550 DOI: 10.1093/narcan/zcaa006  1
2020 Pereira C, Smolka MB, Weiss RS, Brieño-Enríquez MA. ATR Signaling in Mammalian Meiosis: From Upstream Scaffolds to Downstream Signaling. Environmental and Molecular Mutagenesis. PMID 32725817 DOI: 10.1002/Em.22401  1
2020 Beck WHJ, Kim D, Das J, Yu H, Smolka MB, Mao Y. Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB. Iscience. 23: 101300. PMID 32622269 DOI: 10.1016/J.Isci.2020.101300  1
2020 Shin JH, Lanz M, Smolka MB, Dörr T. Characterization of an anti-FLAG antibody binding protein in V. cholerae. Biochemical and Biophysical Research Communications. PMID 32505345 DOI: 10.1016/J.Bbrc.2020.05.169  1
2020 Waterman DP, Haber JE, Smolka MB. Checkpoint Responses to DNA Double-Strand Breaks. Annual Review of Biochemistry. PMID 32176524 DOI: 10.1146/Annurev-Biochem-011520-104722  0.01
2019 Yugandhar K, Wang TY, Leung AK, Lanz MC, Motorykin I, Liang J, Shayhidin EE, Smolka MB, Zhang S, Yu H. MaXLinker: proteome-wide cross-link identifications with high specificity and sensitivity. Molecular & Cellular Proteomics : McP. PMID 31839598 DOI: 10.1074/Mcp.Tir119.001847  1
2019 Wan M, Sulpizio AG, Akturk A, Beck WHJ, Lanz M, Faça VM, Smolka MB, Vogel JP, Mao Y. Deubiquitination of phosphoribosyl-ubiquitin conjugates by phosphodiesterase-domain-containing effectors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31690664 DOI: 10.1073/Pnas.1916287116  1
2019 Sulpizio A, Minelli ME, Wan M, Burrowes PD, Wu X, Sanford EJ, Shin JH, Williams BC, Goldberg ML, Smolka MB, Mao Y. Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ. Elife. 8. PMID 31682223 DOI: 10.7554/Elife.51162  1
2019 Baile MG, Guiney EL, Sanford EJ, MacGurn JA, Smolka MB, Emr SD. Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain. Molecular Biology of the Cell. mbcE19080451. PMID 31618110 DOI: 10.1091/Mbc.E19-08-0451  1
2019 Lanz MC, Dibitetto D, Smolka MB. DNA damage kinase signaling: checkpoint and repair at 30 years. The Embo Journal. e101801. PMID 31393028 DOI: 10.15252/Embj.2019101801  1
2019 Memisoglu G, Lanz MC, Eapen VV, Jordan JM, Lee K, Smolka MB, Haber JE. Mec1 Autophosphorylation and Ddc2 Phosphorylation Regulates DNA Damage Checkpoint Signaling. Cell Reports. 28: 1090-1102.e3. PMID 31340146 DOI: 10.1016/J.Celrep.2019.06.068  0.01
2019 Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F. Progranulin deficiency leads to reduced glucocerebrosidase activity. Plos One. 14: e0212382. PMID 31291241 DOI: 10.1371/Journal.Pone.0212382  1
2019 Shami Shah A, Batrouni AG, Kim D, Punyala A, Cao W, Han C, Goldberg ML, Smolka MB, Baskin JM. PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. Cell Reports. 27: 2157-2170.e8. PMID 31091453 DOI: 10.1016/J.Celrep.2019.04.060  1
2019 Massey DJ, Kim D, Brooks KE, Smolka MB, Koren A. Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing. Genes. 10. PMID 30987063 DOI: 10.3390/Genes10040269  1
2019 Sulpizio A, Minelli ME, Wan M, Burrowes PD, Wu X, Sanford EJ, Shin J, Williams BC, Goldberg ML, Smolka MB, Mao Y. Author response: Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ Elife. DOI: 10.7554/Elife.51162.034  1
2018 Kim D, Liu Y, Oberly S, Freire R, Smolka MB. ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells. Nucleic Acids Research. PMID 30010936 DOI: 10.1093/Nar/Gky625  1
2018 Lanz MC, Oberly S, Sanford EJ, Sharma S, Chabes A, Smolka MB. Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling. Genes & Development. PMID 29899143 DOI: 10.1101/Gad.308148.117  1
2018 Bastos de Oliveira FM, Kim D, Lanz M, Smolka MB. Quantitative Analysis of DNA Damage Signaling Responses to Chemical and Genetic Perturbations. Methods in Molecular Biology (Clifton, N.J.). 1672: 645-660. PMID 29043653 DOI: 10.1007/978-1-4939-7306-4_42  1
2017 Liu Y, Cussiol JR, Dibitetto D, Sims JR, Twayana S, Weiss RS, Freire R, Marini F, Pellicioli A, Smolka MB. TOPBP1(Dpb11) plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1(Rad9). The Journal of Cell Biology. PMID 28228534 DOI: 10.1083/Jcb.201607031  1
2016 Cabrera E, Hernández-Pérez S, Koundrioukoff S, Debatisse M, Kim D, Smolka MB, Freire R, Gillespie DA. PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1. Oncogene. PMID 27375025 DOI: 10.1038/Onc.2016.239  1
2016 Sullivan PM, Zhou X, Robins AM, Paushter DH, Kim D, Smolka MB, Hu F. The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Acta Neuropathologica Communications. 4: 51. PMID 27193190 DOI: 10.1186/S40478-016-0324-5  1
2016 Cussiol JR, Dibitetto D, Pellicioli A, Smolka MB. Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast. Chromosoma. PMID 27165041 DOI: 10.1007/S00412-016-0600-Y  1
2016 Liu Y, Smolka MB. TOPBP1 takes RADical command in recombinational DNA repair. The Journal of Cell Biology. PMID 26811424 DOI: 10.1083/Jcb.201601028  1
2016 Bai G, Smolka MB, Schimenti JC. Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. Plos Genetics. 12: e1005787. PMID 26765334 DOI: 10.1371/Journal.Pgen.1005787  1
2015 Dibitetto D, Ferrari M, Rawal CC, Balint A, Kim T, Zhang Z, Smolka MB, Brown GW, Marini F, Pellicioli A. Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks. Nucleic Acids Research. PMID 26490958 DOI: 10.1093/Nar/Gkv1080  1
2015 Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F. Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin. The Journal of Cell Biology. 210: 991-1002. PMID 26370502 DOI: 10.1083/Jcb.201502029  1
2015 Jablonowski CM, Cussiol JR, Oberly S, Yimit A, Balint A, Kim T, Zhang Z, Brown GW, Smolka MB. Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase. Genetics. PMID 26362319 DOI: 10.1534/Genetics.115.181479  1
2015 Silva JA, Pompeu DG, Smolka MB, Gozzo FC, Comar M, Eberlin MN, Granjeiro PA, Marangoni S. Primary Structure of a Trypsin Inhibitor (Copaifera langsdorffii Trypsin Inhibitor-1) Obtained from C. langsdorffii Seeds. Journal of Biomolecular Techniques : Jbt. 26: 90-102. PMID 26207098 DOI: 10.7171/Jbt.15-2603-002  1
2015 Balint A, Kim T, Gallo D, Cussiol JR, Bastos de Oliveira FM, Yimit A, Ou J, Nakato R, Gurevich A, Shirahige K, Smolka MB, Zhang Z, Brown GW. Assembly of Slx4 signaling complexes behind DNA replication forks. The Embo Journal. PMID 26113155 DOI: 10.15252/Embj.201591190  1
2015 Cussiol JR, Jablonowski CM, Yimit A, Brown GW, Smolka MB. Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. The Embo Journal. 34: 1704-17. PMID 25896509 DOI: 10.15252/Embj.201490834  1
2015 Bastos de Oliveira FM, Kim D, Cussiol JR, Das J, Jeong MC, Doerfler L, Schmidt KH, Yu H, Smolka MB. Phosphoproteomics reveals distinct modes of Mec1/ATR signaling during DNA replication. Molecular Cell. 57: 1124-32. PMID 25752575 DOI: 10.1016/J.Molcel.2015.01.043  1
2014 Wei X, Das J, Fragoza R, Liang J, Bastos de Oliveira FM, Lee HR, Wang X, Mort M, Stenson PD, Cooper DN, Lipkin SM, Smolka MB, Yu H. A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations. Plos Genetics. 10: e1004819. PMID 25502805 DOI: 10.1371/Journal.Pgen.1004819  1
2014 Hsu F, Luo X, Qiu J, Teng YB, Jin J, Smolka MB, Luo ZQ, Mao Y. The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 10538-43. PMID 25006264 DOI: 10.1073/Pnas.1402605111  1
2014 de Oliveira FM, Smolka MB. Identification of DNA damage checkpoint-dependent protein interactions in Saccharomyces cerevisiae using quantitative mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1156: 251-63. PMID 24791994 DOI: 10.1007/978-1-4939-0685-7_17  1
2013 Viswanatha R, Wayt J, Ohouo PY, Smolka MB, Bretscher A. Interactome analysis reveals ezrin can adopt multiple conformational states. The Journal of Biological Chemistry. 288: 35437-51. PMID 24151071 DOI: 10.1074/Jbc.M113.505669  1
2013 Scafoglio C, Smolka M, Zhou H, Perissi V, Rosenfeld MG. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. Plos One. 8: e59986. PMID 23690919 DOI: 10.1371/Journal.Pone.0059986  1
2013 Ohouo PY, Bastos de Oliveira FM, Liu Y, Ma CJ, Smolka MB. DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9. Nature. 493: 120-4. PMID 23160493 DOI: 10.1038/Nature11658  1
2012 Ohouo PY, Smolka MB. The many roads to checkpoint activation. Cell Cycle (Georgetown, Tex.). 11: 4495. PMID 23222063 DOI: 10.4161/Cc.22933  1
2012 Viswanatha R, Ohouo PY, Smolka MB, Bretscher A. Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells. The Journal of Cell Biology. 199: 969-84. PMID 23209304 DOI: 10.1083/Jcb.201207047  1
2012 Smolka MB, Bastos de Oliveira FM, Harris MR, de Bruin RA. The checkpoint transcriptional response: make sure to turn it off once you are satisfied. Cell Cycle (Georgetown, Tex.). 11: 3166-74. PMID 22895177 DOI: 10.4161/Cc.21197  1
2012 Travesa A, Kuo D, de Bruin RA, Kalashnikova TI, Guaderrama M, Thai K, Aslanian A, Smolka MB, Yates JR, Ideker T, Wittenberg C. DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. The Embo Journal. 31: 1811-22. PMID 22333915 DOI: 10.1038/Emboj.2012.28  1
2012 Bastos de Oliveira FM, Harris MR, Brazauskas P, de Bruin RA, Smolka MB. Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. The Embo Journal. 31: 1798-810. PMID 22333912 DOI: 10.1038/Emboj.2012.27  1
2011 MacGurn JA, Hsu PC, Smolka MB, Emr SD. TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell. 147: 1104-17. PMID 22118465 DOI: 10.1016/J.Cell.2011.09.054  1
2011 Ohouo PY, Smolka MB. A touching moment for Smc5/6: from ssDNA binding to repair. Cell Cycle (Georgetown, Tex.). 10: 1190-1. PMID 21436624 DOI: 10.4161/Cc.10.8.15380  1
2010 Ohouo PY, Bastos de Oliveira FM, Almeida BS, Smolka MB. DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response. Molecular Cell. 39: 300-6. PMID 20670896 DOI: 10.1016/J.Molcel.2010.06.019  1
2010 Smolka M. Fine-tuning the DNA damage response: Protein phosphatase 2A checks on CHK2 Cell Cycle. 9: 862-863. PMID 20348841 DOI: 10.4161/Cc.9.5.10906  1
2009 Wagner MV, Smolka MB, de Bruin RA, Zhou H, Wittenberg C, Dowdy SF. Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae. Plos One. 4: e4300. PMID 19172996 DOI: 10.1371/Journal.Pone.0004300  1
2009 Brum IJB, Martins-de-Souza D, Smolka MB, Novello JC, Galembeck E. Web Based Theoretical Protein pI, MW and 2DE Map Journal of Computer Science & Systems Biology. 2009. DOI: 10.4172/Jcsb.1000020  1
2008 Payne SH, Yau M, Smolka MB, Tanner S, Zhou H, Bafna V. Phosphorylation-specific MS/MS scoring for rapid and accurate phosphoproteome analysis. Journal of Proteome Research. 7: 3373-81. PMID 18563926 DOI: 10.1021/Pr800129M  1
2008 Pham P, Smolka MB, Calabrese P, Landolph A, Zhang K, Zhou H, Goodman MF. Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase. The Journal of Biological Chemistry. 283: 17428-39. PMID 18417471 DOI: 10.1074/Jbc.M802121200  1
2008 Albuquerque CP, Smolka MB, Payne SH, Bafna V, Eng J, Zhou H. A multidimensional chromatography technology for in-depth phosphoproteome analysis. Molecular & Cellular Proteomics : McP. 7: 1389-96. PMID 18407956 DOI: 10.1074/Mcp.M700468-Mcp200  1
2007 Smolka MB, Albuquerque CP, Chen SH, Zhou H. Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proceedings of the National Academy of Sciences of the United States of America. 104: 10364-9. PMID 17563356 DOI: 10.1073/Pnas.0701622104  1
2007 Martins-de-Souza D, Martins D, Astua-Monge G, Coletta-Filho HD, Winck FV, Baldasso PA, de Oliveira BM, Marangoni S, Machado MA, Novello JC, Smolka MB. Absence of classical heat shock response in the citrus pathogen Xylella fastidiosa. Current Microbiology. 54: 119-23. PMID 17211542 DOI: 10.1007/S00284-006-0215-2  1
2007 Chen SH, Smolka MB, Zhou H. Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 282: 986-95. PMID 17114794 DOI: 10.1074/Jbc.M609322200  1
2007 Maciel HPF, Gouvêa CMCP, Toyama M, Smolka M, Marangoni S, Pastore GM. Extraction, purification and biochemical characterization of a peroxidase from Copaifera langsdorffii leaves Quimica Nova. 30: 1067-1071. DOI: 10.1590/S0100-40422007000500003  1
2007 zhou h, Smolka MB, Albuquerque C, Chen S. Quantitative Phosphoproteomic Analysis Identifies Targets of the DNA Damage Checkpoint Kinases in Yeast The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A659-D  1
2006 Smolka MB, Chen SH, Maddox PS, Enserink JM, Albuquerque CP, Wei XX, Desai A, Kolodner RD, Zhou H. An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. The Journal of Cell Biology. 175: 743-53. PMID 17130285 DOI: 10.1083/Jcb.200605081  1
2006 Enserink JM, Smolka MB, Zhou H, Kolodner RD. Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae. The Journal of Cell Biology. 175: 729-41. PMID 17130284 DOI: 10.1083/Jcb.200605080  1
2006 Pereira DR, Martins D, Winck FV, Smolka MB, Nishimura NF, Rabelo-Gonçalves EM, Hara NH, Marangoni S, Zeitune JM, Novello JC. Comparative analysis of two-dimensional electrophoresis maps (2-DE) of Helicobacter pylori from Brazilian patients with chronic gastritis and duodenal ulcer: a preliminary report. Revista Do Instituto De Medicina Tropical De Sã£O Paulo. 48: 175-7. PMID 16847509 DOI: 10.1590/S0036-46652006000300011  1
2005 Smolka MB, Albuquerque CP, Chen SH, Schmidt KH, Wei XX, Kolodner RD, Zhou H. Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. Molecular & Cellular Proteomics : McP. 4: 1358-69. PMID 15972895 DOI: 10.1074/Mcp.M500115-Mcp200  1
2004 Macedo ML, Freire Md, Martins LT, Martinez DS, Gomes VM, Smolka MB, Toyama MH, Marangoni S, Coelho LC. Novel protein from Labramia bojeri A. DC. seeds homologue to Kunitz-type trypsin inhibitor with lectin-like properties. Journal of Agricultural and Food Chemistry. 52: 7548-54. PMID 15675802 DOI: 10.1021/Jf048535P  1
2003 Smolka MB, Martins-de-Souza D, Martins D, Winck FV, Santoro CE, Castellari RR, Ferrari F, Brum IJ, Galembeck E, Della Coletta Filho H, Machado MA, Marangoni S, Novello JC. Proteome analysis of the plant pathogen Xylella fastidiosa reveals major cellular and extracellular proteins and a peculiar codon bias distribution. Proteomics. 3: 224-37. PMID 12601815 DOI: 10.1002/Pmic.200390031  1
2002 Smolka M, Zhou H, Aebersold R. Quantitative protein profiling using two-dimensional gel electrophoresis, isotope-coded affinity tag labeling, and mass spectrometry Molecular & Cellular Proteomics : McP. 1: 19-29. PMID 12096137 DOI: 10.1074/Mcp.M100013-Mcp200  1
2001 Freire MG, Machado OL, Smolka MB, Marangoni S, Novello JC, Macedo ML. Isolation and characterization of isolectins from Talisia esculenta seeds. Journal of Protein Chemistry. 20: 495-500. PMID 11760124 DOI: 10.1023/A:1012510614429  1
2001 Smolka MB, Zhou H, Purkayastha S, Aebersold R. Optimization of the isotope-coded affinity tag-labeling procedure for quantitative proteome analysis. Analytical Biochemistry. 297: 25-31. PMID 11567524 DOI: 10.1006/Abio.2001.5318  1
2000 Smolka MB, Zoppi CC, Alves AA, Silveira LR, Marangoni S, Pereira-Da-Silva L, Novello JC, Macedo DV. HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R1539-45. PMID 11049834 DOI: 10.1152/Ajpregu.2000.279.5.R1539  1
1998 Smolka MB, Marangoni S, Oliveira B, Novello JC. Purification and partial characterization of a thrombin-like enzyme, balterobin, from the venom of Bothrops alternatus. Toxicon : Official Journal of the International Society On Toxinology. 36: 1059-63. PMID 9690798 DOI: 10.1016/S0041-0101(98)80008-1  1
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