| Year |
Citation |
Score |
| 2023 |
Dos Ramos Almeida CJL, Veras FP, Paiva IM, Schneider AH, Silva JDC, Gomes GF, Costa VF, Silva BMS, Caetite DB, Silva CMS, Salina ACG, Martins R, Bonilha CS, Cunha LD, Jamur MC, ... ... Cunha FQ, et al. Neutrophil virucidal activity against SARS-CoV-2 is mediated by NETs. The Journal of Infectious Diseases. PMID 38015657 DOI: 10.1093/infdis/jiad526 |
0.498 |
|
| 2023 |
Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, Kavaguti SK, Carlotti AP, Carmona F, Franklin BS, Cunha TM, ... ... Cunha FQ, et al. Pediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction. British Journal of Pharmacology. PMID 37990806 DOI: 10.1111/bph.16286 |
0.495 |
|
| 2023 |
Córneo ES, Veras FP, Gomes GF, Schneider AH, Manuella B, Almeida CJLR, Silva CM, Martins RB, Batah SS, Simon CS, Prestes GDS, Alves-Filho JC, Arruda E, Louzada-Junior P, de Oliveira RDR, ... ... Cunha FQ, et al. Enoxaparin improves COVID-19 by reducing Neutrophils Extracellular Traps (NETs) production. Clinical Immunology (Orlando, Fla.). 257: 109836. PMID 37951516 DOI: 10.1016/j.clim.2023.109836 |
0.536 |
|
| 2023 |
Leite JA, Menezes L, Martins E, Rodrigues TS, Tavares L, Ebering A, Schelmbauer C, Martelossi Cebinelli GC, Zinina V, Golden A, Soshnikova N, Zamboni DS, Cunha FQ, Huber M, Silva JS, et al. AIM2 promotes T17 cells differentiation by regulating RORγt transcription activity. Iscience. 26: 108134. PMID 37867943 DOI: 10.1016/j.isci.2023.108134 |
0.464 |
|
| 2023 |
Damasceno LEA, Cunha TM, Cunha FQ, Sparwasser T, Alves-Filho JC. A clinically-relevant STING agonist restrains human T17 cell inflammatory profile. International Immunopharmacology. 124: 111007. PMID 37778170 DOI: 10.1016/j.intimp.2023.111007 |
0.503 |
|
| 2023 |
Schneider AH, Taira TM, Públio GA, da Silva Prado D, Yabuta PBD, Dos Santos JC, Machado CC, de Souza FFL, Venturini LGR, de Oliveira RDR, Cunha TM, Alves-Filho JC, Louzada-Júnior P, da Silva TA, Fukada SY, ... Cunha FQ, et al. Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL-induced osteoclastogenesis. British Journal of Pharmacology. PMID 37625900 DOI: 10.1111/bph.16227 |
0.494 |
|
| 2023 |
de Lima MHF, Machado CC, Nascimento DC, Silva CMS, Toller-Kawahisa JE, Rodrigues TS, Veras FP, Pontelli MC, Castro IA, Zamboni DS, Filho JA, Cunha TM, Arruda E, da Cunha LD, Oliveira RDR, ... Cunha FQ, et al. The TIGIT T regulatory cells subset associates with nosocomial infection and fatal outcome in COVID-19 patients under mechanical ventilation. Scientific Reports. 13: 13599. PMID 37604833 DOI: 10.1038/s41598-023-39924-7 |
0.488 |
|
| 2023 |
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, ... ... Cunha FQ, et al. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils. Nature Communications. 14: 4280. PMID 37460614 DOI: 10.1038/s41467-023-40021-6 |
0.484 |
|
| 2023 |
Guimarães RM, Aníbal-Silva CE, Davoli-Ferreira M, Gomes FIF, Mendes AS, Cavallini MCM, Fonseca MM, Damasceno S, Andrade LP, Colonna M, Rivat C, Cunha FQ, Alves-Filho JC, Cunha TM. Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling. Elife. 12. PMID 37254842 DOI: 10.7554/eLife.78515 |
0.521 |
|
| 2023 |
Barreto EA, Cruz AS, Veras FP, Martins R, Bernardelli RS, Paiva IM, Lima TM, Singh Y, Guimarães RC, Damasceno S, Pereira N, Alves JM, Gonçalves TT, Forato J, Muraro SP, ... ... Cunha FQ, et al. COVID-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217119120. PMID 37186819 DOI: 10.1073/pnas.2217119120 |
0.448 |
|
| 2023 |
Silva BM, Gomes GF, Veras FP, Cambier S, Silva GV, Quadros AU, Caetité DB, Nascimento DC, Silva CM, Costa Silva JC, Damasceno S, Schneider AH, Beretta F, Batah SS, Castro IM, ... ... Cunha FQ, et al. C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps. The Journal of Clinical Investigation. PMID 37104043 DOI: 10.1172/JCI163105 |
0.5 |
|
| 2023 |
de Melo BMS, Veras FP, Zwicky P, Lima D, Ingelfinger F, Varela T, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, ... ... Cunha FQ, et al. S100A9 drives the chronification of psoriasiform inflammation by inducing IL-23/type 3 immunity. The Journal of Investigative Dermatology. PMID 36921684 DOI: 10.1016/j.jid.2023.02.026 |
0.544 |
|
| 2023 |
Veras FP, Gomes GF, Silva BMS, Caetité DB, Almeida CJLR, Silva CMS, Schneider AH, Corneo ES, Bonilha CS, Batah SS, Martins R, Arruda E, Fabro AT, Alves-Filho JC, Cunha TM, ... Cunha FQ, et al. Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model. Respiratory Research. 24: 66. PMID 36864506 DOI: 10.1186/s12931-023-02336-2 |
0.459 |
|
| 2023 |
Rodrigues TS, Caetano CCS, de Sá KSG, Almeida L, Becerra A, Gonçalves AV, de Sousa Lopes L, Oliveira S, Mascarenhas DPA, Batah SS, Silva BM, Gomes GF, Castro R, Martins RB, Avila J, ... ... Cunha FQ, et al. CASP4/11 contributes to NLRP3 activation and COVID-19 exacerbation. The Journal of Infectious Diseases. PMID 36763010 DOI: 10.1093/infdis/jiad037 |
0.555 |
|
| 2023 |
Borghi SM, Zaninelli TH, Saraiva-Santos T, Bertozzi MM, Cardoso RDR, Carvalho TT, Ferraz CR, Camilios-Neto D, Cunha FQ, Cunha TM, Pinho-Ribeiro FA, Casagrande R, Verri WA. Brief research report: Repurposing pentoxifylline to treat intense acute swimming-Induced delayed-onset muscle soreness in mice: Targeting peripheral and spinal cord nociceptive mechanisms. Frontiers in Pharmacology. 13: 950314. PMID 36703752 DOI: 10.3389/fphar.2022.950314 |
0.645 |
|
| 2023 |
Oliveira I, Costa V, Veras F, Ferreira I, Cunha F, Cunha T, Monteiro W, Arantes E, Pucca M. A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: PDE, a Rattlesnake Phosphodiesterase. Toxins. 15. PMID 36668864 DOI: 10.3390/toxins15010044 |
0.488 |
|
| 2022 |
Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, ... ... Cunha FQ, et al. Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation. Cell Reports. 41: 111897. PMID 36577385 DOI: 10.1016/j.celrep.2022.111897 |
0.567 |
|
| 2022 |
Borges VF, Galant LS, Kanashiro A, Castanheira FVES, Monteiro VVS, Duarte DÂ, Rodrigues FC, Silva CMS, Schneider AH, Cebinelli GCM, de Lima MHF, Viola JPB, Cunha TM, da Costa Neto CM, Alves-Filho JCF, ... ... Cunha FQ, et al. FK506 impairs neutrophil migration that results in increased polymicrobial sepsis susceptibility. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 36401631 DOI: 10.1007/s00011-022-01669-w |
0.514 |
|
| 2022 |
Maganin AG, Souza GR, Fonseca MD, Lopes AH, Mano Guimarães RM, Dagostin A, Cecilio NT, Mendes AS, Gonçalves WA, Silva CE, Fernandes Gomes FI, Mauriz Marques LM, Silva RL, Arruda LM, Santana DA, ... ... Cunha FQ, et al. Meningeal dendritic cells drive neuropathic pain through elevation of the kynurenine metabolic pathway in mice. The Journal of Clinical Investigation. PMID 36227694 DOI: 10.1172/JCI153805 |
0.487 |
|
| 2022 |
de Almeida L, da Silva ALN, Rodrigues TS, Oliveira S, Ishimoto AY, Seribelli AA, Becerra A, Andrade WA, Ataide MA, Caetano CCS, de Sá KSG, Pelisson N, Martins RB, de Paula Souza J, Arruda E, ... ... Cunha FQ, et al. Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection. Science Advances. 8: eabo5400. PMID 36103544 DOI: 10.1126/sciadv.abo5400 |
0.505 |
|
| 2022 |
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, Lee-Montiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, ... ... Cunha FQ, et al. Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice. Acs Omega. 7: 31935-31944. PMID 36097511 DOI: 10.1021/acsomega.2c02794 |
0.549 |
|
| 2022 |
Wanderley CWS, Maganin A, Adjafre B, Mendes AS, Anibal Silva CE, Quadros AU, Luiz JPM, Silva CMS, Silva NR, Oliveira FF, Gomes FIF, Restrepo JLJ, Speck-Hernandez CA, Turaça F, Silva GVL, ... ... Cunha FQ, et al. PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling. Cancer Immunology Research. PMID 36083496 DOI: 10.1158/2326-6066.CIR-22-0003 |
0.462 |
|
| 2022 |
Crunfli F, Carregari VC, Veras FP, Silva LS, Nogueira MH, Antunes ASLM, Vendramini PH, Valença AGF, Brandão-Teles C, Zuccoli GDS, Reis-de-Oliveira G, Silva-Costa LC, Saia-Cereda VM, Smith BJ, Codo AC, ... ... Cunha FQ, et al. Morphological, cellular, and molecular basis of brain infection in COVID-19 patients. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200960119. PMID 35951647 DOI: 10.1073/pnas.2200960119 |
0.434 |
|
| 2022 |
Silva CMS, Wanderley CWS, Veras FP, Gonçalves AV, Lima MHF, Toller-Kawahisa JE, Gomes GF, Nascimento DC, Monteiro VVS, Paiva IM, Almeida CJLR, Caetité DB, Silva JC, Lopes MIF, Bonjorno LP, ... ... Cunha FQ, et al. Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology. Critical Care (London, England). 26: 206. PMID 35799268 DOI: 10.1186/s13054-022-04062-5 |
0.483 |
|
| 2022 |
Franchin M, Luiz Rosalen P, da Silva Prado D, César Paraluppi M, Leal Silva R, Damasceno LEA, Morelo DFC, Napimoga MH, Cunha FQ, Alves-Filho JC, Cunha TM. Cinnamoyloxy-mammeisin, a coumarin from propolis of stingless bees, attenuates Th17 cell differentiation and autoimmune inflammation via STAT3 inhibition. European Journal of Pharmacology. 929: 175127. PMID 35787889 DOI: 10.1016/j.ejphar.2022.175127 |
0.556 |
|
| 2022 |
Salina ACG, Dos Santos D, Rodrigues TS, Fortes-Rocha M, Freitas-Filho EG, Alzamora-Terrel DL, Castro IMS, Fraga-Silva TF, de Lima MHF, Nascimento DC, Silva CM, Toller-Kawahisa JE, Becerra A, Oliveira S, Caetite DB, ... ... Cunha FQ, et al. Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells. Elife. 11. PMID 35666101 DOI: 10.7554/eLife.74443 |
0.555 |
|
| 2022 |
Damasceno LEA, Cebinelli GCM, Fernandes MF, Nascimento DC, Públio GA, Vinolo MAR, Oliveira SC, Sparwasser T, Cunha TM, Cunha FQ, Alves-Filho JC. STING is an intrinsic checkpoint inhibitor that restrains the T17 cell pathogenic program. Cell Reports. 39: 110838. PMID 35613599 DOI: 10.1016/j.celrep.2022.110838 |
0.521 |
|
| 2022 |
Puhl AC, Gomes GF, Damasceno S, Godoy AS, Noske GD, Nakamura AM, Gawriljuk VO, Fernandes RS, Monakhova N, Riabova O, Lane TR, Makarov V, Veras FP, Batah SS, Fabro AT, ... ... Cunha FQ, et al. Pyronaridine Protects against SARS-CoV-2 Infection in Mouse. Acs Infectious Diseases. PMID 35609344 DOI: 10.1021/acsinfecdis.2c00091 |
0.517 |
|
| 2022 |
Pontelli MC, Castro IA, Martins RB, La Serra L, Veras FP, Nascimento DC, Silva CM, Cardoso RS, Rosales R, Gomes R, Lima TM, Souza JP, Vitti BC, Caetité DB, de Lima MHF, ... ... Cunha FQ, et al. SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients. Journal of Molecular Cell Biology. PMID 35451490 DOI: 10.1093/jmcb/mjac021 |
0.483 |
|
| 2022 |
Castro PATS, Machanocker DH, Luna GF, Barbosa GM, Cunha JE, Cunha TM, Cunha FQ, Russo TL, Salvini TF. Clinical-Like Cryotherapy in Acute Knee Arthritis Protects Neuromuscular Junctions of Quadriceps and Reduces Joint Inflammation in Mice. Biomed Research International. 2022: 7442289. PMID 35103239 DOI: 10.1155/2022/7442289 |
0.509 |
|
| 2022 |
Batah SS, Benatti MN, Siyuan L, Telini WM, Barboza JO, Menezes MB, Nadai TR, Sá KSG, Vaswani CM, Gupta S, Zamboni DS, Wada DT, Calado RT, Oliveira RDR, Louzada-Junior P, ... ... Cunha FQ, et al. COVID-19 bimodal clinical and pathological phenotypes. Clinical and Translational Medicine. 12: e648. PMID 35075808 DOI: 10.1002/ctm2.648 |
0.397 |
|
| 2022 |
Borghi SM, Bussulo SKD, Pinho-Ribeiro FA, Fattori V, Carvalho TT, Rasquel-Oliveira FS, Zaninelli TH, Ferraz CR, Casella AMB, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation. Frontiers in Pharmacology. 12: 734091. PMID 35069187 DOI: 10.3389/fphar.2021.734091 |
0.653 |
|
| 2022 |
Castro PATS, Barbosa GM, Machanocker DH, Peres RS, Cunha TM, Cunha JE, Oliveira FFB, Ramalho FS, Russo TL, Cunha FQ, Salvini TF. Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice. Plos One. 17: e0261667. PMID 35061737 DOI: 10.1371/journal.pone.0261667 |
0.535 |
|
| 2021 |
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, LeeMontiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, ... ... Cunha FQ, et al. Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice. Biorxiv : the Preprint Server For Biology. PMID 34981062 DOI: 10.1101/2021.12.16.472155 |
0.541 |
|
| 2021 |
Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Santos BC, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, ... ... Cunha FQ, et al. Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health? The Science of the Total Environment. 152345. PMID 34942250 DOI: 10.1016/j.scitotenv.2021.152345 |
0.443 |
|
| 2021 |
Almeida GM, Souza JP, Mendes ND, Pontelli MC, Pinheiro NR, Nogueira GO, Cardoso RS, Paiva IM, Ferrari GD, Veras FP, Cunha FQ, Horta-Junior JAC, Alberici LC, Cunha TM, Podolsky-Gondim GG, et al. Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response. Frontiers in Neuroscience. 15: 674576. PMID 34887719 DOI: 10.3389/fnins.2021.674576 |
0.473 |
|
| 2021 |
Saraiva AL, Peres RS, Veras FP, Talbot J, de Lima KA, Luiz JPM, Cunha TM, Louzada-Junior P, Cunha FQ, Alves-Filho JC. Citrullinated human fibrinogen triggers arthritis through an inflammatory response mediated by IL-23/IL-17 immune axis. International Immunopharmacology. 101: 108363. PMID 34810129 DOI: 10.1016/j.intimp.2021.108363 |
0.58 |
|
| 2021 |
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, ... ... Cunha FQ, et al. Sepsis expands a CD39 plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. Immunity. PMID 34473957 DOI: 10.1016/j.immuni.2021.08.005 |
0.511 |
|
| 2021 |
Silva CM, Wanderley CWS, Veras FP, Sonego F, Nascimento DC, Gonçalves AV, Martins TV, Colón DF, Borges VF, Brauer VS, Damasceno LEA, Silva KP, Toller-Kawahisa JE, Batah SS, Souza ALJ, ... ... Cunha FQ, et al. Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation. Blood. PMID 34407544 DOI: 10.1182/blood.2021011525 |
0.498 |
|
| 2021 |
de Lima MHF, Hiroki CH, de Fátima Borges V, Cebinelli GCM, Santos J, Rosa MH, Silva CMS, Wanderley CWS, Gonçalves AV, Silva Quirino GF, Zamboni DS, Cunha TM, Filho JA, Cunha FQ. Sepsis-induced immunosuppression is marked by an expansion of a highly suppressive repertoire of FOXP3 +T regulatory cells-expressing TIGIT. The Journal of Infectious Diseases. PMID 34379757 DOI: 10.1093/infdis/jiab405 |
0.462 |
|
| 2021 |
Trevelin SC, Sag CM, Zhang M, Alves-Filho JC, Cunha TM, Santos CXD, Sawyer G, Murray T, Brewer A, Laurindo FRM, Protti A, Lopes LR, Ivetic A, Cunha FQ, Shah AM. Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4. Shock (Augusta, Ga.). 56: 268-277. PMID 34276040 DOI: 10.1097/SHK.0000000000001706 |
0.546 |
|
| 2021 |
Heluany CS, Donate PB, Schneider AH, Fabris AL, Gomes RA, Villas-Boas IM, Tambourgi DV, Silva TAD, Trossini GHG, Nalesso G, Silveira ELV, Cunha FQ, Farsky SHP. Hydroquinone Exposure Worsens Rheumatoid Arthritis through the Activation of the Aryl Hydrocarbon Receptor and Interleukin-17 Pathways. Antioxidants (Basel, Switzerland). 10. PMID 34200499 DOI: 10.3390/antiox10060929 |
0.316 |
|
| 2021 |
Lopes MI, Bonjorno LP, Giannini MC, Amaral NB, Menezes PI, Dib SM, Gigante SL, Benatti MN, Rezek UC, Emrich-Filho LL, Sousa BAA, Almeida SCL, Luppino Assad R, Veras FP, Schneider A, ... ... Cunha FQ, et al. Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial. Rmd Open. 7. PMID 33542047 DOI: 10.1136/rmdopen-2020-001455 |
0.41 |
|
| 2021 |
Donate PB, Alves de Lima K, Peres RS, Almeida F, Fukada SY, Silva TA, Nascimento DC, Cecilio NT, Talbot J, Oliveira RD, Passos GA, Alves-Filho JC, Cunha TM, Louzada-Junior P, Liew FY, ... Cunha FQ, et al. Cigarette smoke induces in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33443169 DOI: 10.1073/pnas.2017120118 |
0.506 |
|
| 2021 |
Rodrigues TS, de Sá KSG, Ishimoto AY, Becerra A, Oliveira S, Almeida L, Gonçalves AV, Perucello DB, Andrade WA, Castro R, Veras FP, Toller-Kawahisa JE, Nascimento DC, de Lima MHF, Silva CMS, ... ... Cunha FQ, et al. Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients. The Journal of Experimental Medicine. 218. PMID 33231615 DOI: 10.1084/jem.20201707 |
0.535 |
|
| 2020 |
Pontelli MC, Castro IA, Martins RB, Veras FP, Serra L, Nascimento DC, Cardoso RS, Rosales R, Lima TM, Souza JP, Caetité DB, de Lima MHF, Kawahisa JT, Giannini MC, Bonjorno LP, ... ... Cunha FQ, et al. Infection of human lymphomononuclear cells by SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 34013264 DOI: 10.1101/2020.07.28.225912 |
0.461 |
|
| 2020 |
Borghi SM, Fattori V, Carvalho TT, Tatakihara VLH, Zaninelli TH, Pinho-Ribeiro FA, Ferraz CR, Staurengo-Ferrari L, Casagrande R, Pavanelli WR, Cunha FQ, Cunha TM, Pinge-Filho P, Verri WA. Experimental Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NFκB Activation and Cytokine Production. Frontiers in Immunology. 11: 539086. PMID 33574810 DOI: 10.3389/fimmu.2020.539086 |
0.675 |
|
| 2020 |
Schneider AH, Machado CC, Veras FP, Maganin AGM, de Souza FFL, Barroso LC, de Oliveira RDR, Alves-Filho JC, Cunha TM, Fukada SY, Louzada-Júnior P, da Silva TA, Cunha FQ. Neutrophil extracellular traps mediate joint hyperalgesia induced by immune inflammation. Rheumatology (Oxford, England). PMID 33367912 DOI: 10.1093/rheumatology/keaa794 |
0.532 |
|
| 2020 |
Machado VF, Parra RS, Leite CA, Minto SB, Cunha TM, Cunha FQ, Garcia SB, Feitosa MR, da Rocha JJR, Feres O. Experimental Model of Rectal Carcinogenesis Induced by N-Methyl-N-Nitrosoguanidine in Mice with Endoscopic Evaluation. International Journal of Medical Sciences. 17: 2505-2510. PMID 33029093 DOI: 10.7150/ijms.48231 |
0.461 |
|
| 2020 |
Cebinelli GCM, de Lima KA, Silva Castanheira FVE, Hiroki CH, Monteiro VVS, de Lima MHF, Nascimento DCB, Alves Filho JC, Cunha TM, Cunha FQ. CCR2-deficient mice are protected to sepsis by the disruption of the inflammatory monocytes emigration from the bone marrow. Journal of Leukocyte Biology. PMID 33020963 DOI: 10.1002/JLB.4MR0820-049RR |
0.561 |
|
| 2020 |
Cecílio NT, Souza GR, Alves-Filho JC, Cunha FQ, Cunha TM. 9The PI3Kγ/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone. Fundamental & Clinical Pharmacology. PMID 32979233 DOI: 10.1111/fcp.12606 |
0.543 |
|
| 2020 |
Zanata GC, Pinto LG, da Silva NR, Lopes AHP, de Oliveira FFB, Schivo IRS, Cunha FQ, McNaughton P, Cunha TM, Silva RL. Blockade of Bradykinin Receptors or Angiotensin II Type 2 Receptor Prevents Paclitaxel-Associated Acute Pain Syndrome in Mice. European Journal of Pain (London, England). PMID 32965065 DOI: 10.1002/ejp.1660 |
0.487 |
|
| 2020 |
Veras FP, Pontelli MC, Silva CM, Toller-Kawahisa JE, de Lima M, Nascimento DC, Schneider AH, Caetité D, Tavares LA, Paiva IM, Rosales R, Colón D, Martins R, Castro IA, Almeida GM, ... ... Cunha FQ, et al. SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology. The Journal of Experimental Medicine. 217. PMID 32926098 DOI: 10.1084/Jem.20201129 |
0.564 |
|
| 2020 |
Lopes AH, Silva RL, Fonseca MD, Gomes FI, Maganin AG, Ribeiro LS, Marques LMM, Cunha FQ, Alves-Filho JC, Zamboni DS, Lopes NP, Franklin BS, Gombault A, Ramalho FS, Quesniaux VFJ, et al. Molecular basis of carrageenan-induced cytokines production in macrophages. Cell Communication and Signaling : Ccs. 18: 141. PMID 32894139 DOI: 10.1186/S12964-020-00621-X |
0.593 |
|
| 2020 |
Fattori V, Staurengo-Ferrari L, Zaninelli TH, Casagrande R, Oliveira RD, Louzada-Junior P, Cunha TM, Alves-Filho JC, Teixeira MM, Cunha FQ, Amaral FA, Verri WA. IL-33 enhances macrophage release of IL-1β and promotes pain and inflammation in gouty arthritis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 32886146 DOI: 10.1007/S00011-020-01399-X |
0.702 |
|
| 2020 |
Luiz JPM, Toller-Kawahisa JE, Viacava PR, Nascimento DC, Pereira PT, Saraiva AL, Prado DS, LeBert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology. PMID 32745297 DOI: 10.1002/Jlb.1Ma0520-016R |
0.599 |
|
| 2020 |
Davoli-Ferreira M, de Lima KA, Fonseca MM, Guimarães RM, Gomes FI, Cavallini MC, Quadros AU, Kusuda R, Cunha FQ, Alves-Filho JC, Cunha TM. Regulatory T cells counteract neuropathic pain through inhibition of the Th1 response at the site of peripheral nerve injury. Pain. 161: 1730-1743. PMID 32701834 DOI: 10.1097/J.Pain.0000000000001879 |
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| 2020 |
Damasceno LEA, Prado DS, Veras FP, Fonseca MM, Toller-Kawahisa JE, Rosa MH, Públio GA, Martins TV, Ramalho FS, Waisman A, Cunha FQ, Cunha TM, Alves-Filho JC. PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation. The Journal of Experimental Medicine. 217. PMID 32697823 DOI: 10.1084/Jem.20190613 |
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| 2020 |
Prado DS, Veras FP, Ferreira RG, Damasceno LEA, Melo PH, Zamboni DS, Cunha TM, Cunha FQ, Alves-Filho JC. NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32632939 DOI: 10.1096/Fj.202000795R |
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| 2020 |
Erthal RP, Staurengo-Ferrari L, Fattori V, Luiz KG, Cunha FQ, Pescim RR, Cecchini R, Verri WA, Guarnier FA, Alves Fernandes GS. Exposure to low doses of malathion during juvenile and peripubertal periods impairs testicular and sperm parameters in rats: Role of oxidative stress and testosterone. Reproductive Toxicology (Elmsford, N.Y.). 96: 17-26. PMID 32479887 DOI: 10.1016/J.Reprotox.2020.05.013 |
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| 2020 |
Rolfes V, Ribeiro LS, Hawwari I, Böttcher L, Rosero N, Maasewerd S, Santos MLS, Próchnicki T, Silva CMS, Wanderley CWS, Rothe M, Schmidt SV, Stunden HJ, Bertheloot D, Rivas MN, ... ... Cunha FQ, et al. Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Reports. 31: 107615. PMID 32402278 DOI: 10.1016/J.Celrep.2020.107615 |
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| 2020 |
Silva CR, Melo BMS, Silva JR, Lopes AH, Pereira JA, Cecilio NT, Berlink J, Souza GG, Lucas G, Vogl T, Cunha FQ, Alves-Filho JC, Cunha TM. S100A9 plays a pivotal role in a mouse model of herpetic neuralgia via TLR4/TNF pathway. Brain, Behavior, and Immunity. PMID 32243898 DOI: 10.1016/J.Bbi.2020.03.033 |
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| 2020 |
Sacramento LA, Benevides L, Maruyama SR, Tavares L, Fukutani KF, Francozo M, Sparwasser T, Cunha FQ, Almeida RP, da Silva JS, Carregaro V. TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection. Plos Pathogens. 16: e1008435. PMID 32210480 DOI: 10.1371/Journal.Ppat.1008435 |
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| 2020 |
F Gomes FI, Cunha FQ, Cunha TM. Peripheral nitric oxide signaling directly blocks inflammatory pain. Biochemical Pharmacology. 113862. PMID 32081790 DOI: 10.1016/J.Bcp.2020.113862 |
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| 2020 |
Barbosa GM, Cunha JE, Russo TL, Cunha TM, Castro PATS, Oliveira FFB, Cunha FQ, Ramalho FS, Salvini TF. Thirty days after anterior cruciate ligament transection is sufficient to induce signs of knee osteoarthritis in rats: pain, functional impairment, and synovial inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 69: 279-288. PMID 32006078 DOI: 10.1007/S00011-020-01317-1 |
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| 2019 |
Hiroki CH, Toller-Kawahisa JE, Fumagalli MJ, Colon DF, Figueiredo LTM, Fonseca BALD, Franca RFO, Cunha FQ. Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection. Frontiers in Immunology. 10: 3108. PMID 32082301 DOI: 10.3389/Fimmu.2019.03108 |
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| 2019 |
Fonseca MM, Davoli-Ferreira M, Santa-Cecília F, Guimarães RM, Oliveira FFB, Kusuda R, Ferreira DW, Alves-Filho JC, Cunha FQ, Cunha TM. IL-27 Counteracts Neuropathic Pain Development Through Induction of IL-10. Frontiers in Immunology. 10: 3059. PMID 32047492 DOI: 10.3389/Fimmu.2019.03059 |
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| 2019 |
Silva JF, Olivon VC, Mestriner FLAC, Zanotto CZ, Ferreira RG, Ferreira NS, Silva CAA, Luiz JPM, Alves JV, Fazan R, Cunha FQ, Alves-Filho JC, Tostes RC. Acute Increase in -GlcNAc Improves Survival in Mice With LPS-Induced Systemic Inflammatory Response Syndrome. Frontiers in Physiology. 10: 1614. PMID 32038294 DOI: 10.3389/Fphys.2019.01614 |
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| 2019 |
Piñeros AR, de Lima MHF, Rodrigues T, Gembre AF, Bertolini TB, Fonseca MD, Berretta AA, Ramalho LNZ, Cunha FQ, Hori JI, Bonato VLD. Green propolis increases myeloid suppressor cells and CD4Foxp3 cells and reduces Th2 inflammation in the lungs after allergen exposure. Journal of Ethnopharmacology. 112496. PMID 31870795 DOI: 10.1016/J.Jep.2019.112496 |
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| 2019 |
Kanashiro A, Hiroki CH, da Fonseca DM, Birbrair A, Ferreira RG, Bassi GS, Fonseca MD, Kusuda R, Cebinelli G, da Silva KP, Wanderley CW, Menezes GB, Filho JCA, Oliveira AG, Cunha TM, ... ... Cunha FQ, et al. THE ROLE OF NEUTROPHILS IN NEURO-IMMUNE MODULATION. Pharmacological Research. 104580. PMID 31786317 DOI: 10.1016/J.Phrs.2019.104580 |
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| 2019 |
Souto FO, Castanheira FVS, Trevelin SC, Lima BHF, Cebinelli GCM, Turato WM, Auxiliadora-Martins M, Basile-Filho A, Alves-Filho JC, Cunha FQ. Liver X receptor activation impairs neutrophil functions and aggravates sepsis. The Journal of Infectious Diseases. PMID 31783409 DOI: 10.1093/Infdis/Jiz635 |
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| 2019 |
Kusuda R, Carreira EU, Ulloa L, Cunha FQ, Kanashiro A, Cunha TM. Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway. Brain Research. 146567. PMID 31783002 DOI: 10.1016/J.Brainres.2019.146567 |
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| 2019 |
Barbosa GM, Cunha JE, Cunha TM, Martinho LB, Castro PATS, Oliveira FFB, Cunha FQ, Ramalho FS, Salvini TF. Clinical-like cryotherapy improves footprint patterns and reduces synovial inflammation in a rat model of post-traumatic knee osteoarthritis. Scientific Reports. 9: 14518. PMID 31601862 DOI: 10.1038/S41598-019-50958-8 |
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| 2019 |
Awata WMC, Gonzaga NA, Borges VF, Silva CBP, Tanus-Santos JE, Cunha FQ, Tirapelli CR. Perivascular adipose tissue contributes to lethal sepsis-induced vasoplegia in rats. European Journal of Pharmacology. 172706. PMID 31568782 DOI: 10.1016/J.Ejphar.2019.172706 |
0.371 |
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| 2019 |
de Castro-Jorge LA, de Carvalho RVH, Klein TM, Hiroki CH, Lopes AH, Guimarães RM, Fumagalli MJ, Floriano VG, Agostinho MR, Slhessarenko RD, Ramalho FS, Cunha TM, Cunha FQ, da Fonseca BAL, Zamboni DS. The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus. Plos Pathogens. 15: e1007934. PMID 31479495 DOI: 10.1371/Journal.Ppat.1007934 |
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| 2019 |
Cardoso CR, Provinciatto PR, Godoi DF, Fonseca MT, Ferreira BR, Teixeira G, Cunha FQ, Pinzan CF, da Silva JS. The signal transducer and activator of transcription 6 (STAT-6) mediates Th2 inflammation and tissue damage in a murine model of peanut-induced food allergy. Allergologia Et Immunopathologia. PMID 31196774 DOI: 10.1016/J.Aller.2019.02.006 |
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| 2019 |
Corrêa JD, Fernandes GR, Calderaro DC, Mendonça SMS, Silva JM, Albiero ML, Cunha FQ, Xiao E, Ferreira GA, Teixeira AL, Mukherjee C, Leys EJ, Silva TA, Graves DT. Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients. Scientific Reports. 9: 8379. PMID 31182740 DOI: 10.1038/S41598-019-44674-6 |
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| 2019 |
Guimarães RM, Davoli-Ferreira M, Fonseca MM, Damasceno LEA, Santa-Cecilia FV, Kusuda R, Menezes GB, Cunha FQ, Alves-Filho JC, Cunha TM. Frontline Science: Blood-circulating leukocytes fail to infiltrate the spinal cord parenchyma after spared nerve injury. Journal of Leukocyte Biology. PMID 31150565 DOI: 10.1002/Jlb.Hi1118-458R |
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| 2019 |
Borghi SM, Fattori V, Pinho-Ribeiro FA, Domiciano TP, Miranda-Sapla MM, Zaninelli TH, Casagrande R, Pinge-Filho P, Pavanelli WR, Alves-Filho JC, Cunha FQ, Cunha TM, Verri WA. Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice. Journal of Neuroinflammation. 16: 113. PMID 31138231 DOI: 10.1186/S12974-019-1496-2 |
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| 2019 |
Schneider AH, Kanashiro A, Dutra SGV, Souza RDN, Veras FP, Cunha FQ, Ulloa L, Mecawi AS, Reis LC, Malvar DDC. Estradiol replacement therapy regulates innate immune response in ovariectomized arthritic mice. International Immunopharmacology. 72: 504-510. PMID 31055232 DOI: 10.1016/j.intimp.2019.04.048 |
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| 2019 |
Spiller F, de Oliveira Formiga R, Fernandes da Silva Coimbra J, Alves-Filho JC, Cunha TM, Cunha FQ. Targeting nitric oxide as a key modulator of sepsis, arthritis and pain. Nitric Oxide : Biology and Chemistry. PMID 31051258 DOI: 10.1016/J.Niox.2019.04.011 |
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| 2019 |
Lourenco-Gonzalez Y, Fattori V, Domiciano TP, Rossaneis AC, Borghi SM, Zaninelli TH, Bernardy CCF, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators of Inflammation. 2019: 6481812. PMID 31049025 DOI: 10.1155/2019/6481812 |
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| 2019 |
Cunha JE, Barbosa GM, Castro PATS, Luiz BLF, Silva ACA, Russo TL, Vasilceac FA, Cunha TM, Cunha FQ, Salvini TF. Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Scientific Reports. 9: 6366. PMID 31019213 DOI: 10.1038/S41598-019-42546-7 |
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| 2019 |
Wong DVT, Ribeiro-Filho HV, Wanderley CWS, Leite CAVG, Lima JB, Assef ANB, Cajado AG, Batista GLP, González RH, Silva KO, Borges LPC, Alencar NMN, Wilke DV, Cunha TM, Figueira ACM, ... Cunha FQ, et al. SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4. Cancer Chemotherapy and Pharmacology. PMID 31011814 DOI: 10.1007/S00280-019-03844-Z |
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| 2019 |
Wilches-Buitrago L, Viacava PR, Cunha FQ, Alves-Filho JC, Fukada SY. Fructose 1,6-bisphosphate inhibits osteoclastogenesis by attenuating RANKL-induced NF-κB/NFATc-1. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 68: 415-421. PMID 30927049 DOI: 10.1007/S00011-019-01228-W |
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| 2019 |
Silva RL, Silveira GT, Wanderlei CW, Cecilio TN, Maganin AGM, Franchin M, Marques LMM, Lopes NP, Crippa JA, Guimarães FS, Alves-Filho JCF, Cunha FQ, Cunha TM. DMH-cannabidiol, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity by activating A receptor and inhibiting p38. Toxicology and Applied Pharmacology. PMID 30796934 DOI: 10.1016/J.Taap.2019.02.011 |
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| 2019 |
Amarilla AA, Nascimento Santos-Junior N, Figueiredo ML, Mesquita Luiz JP, Fumagalli MJ, Colón DF, Lippi V, Alfonso HL, Lima-Junior DS, Trabuco AC, Spinieli RL, Desidera AC, Leite-Panissi CRA, Lauretti F, Mendoza SES, ... ... Cunha FQ, et al. CCR2 plays a protective role in Rocio virus induced encephalitis by promoting macrophage infiltration into the brain. The Journal of Infectious Diseases. PMID 30715407 DOI: 10.1093/Infdis/Jiz029 |
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| 2019 |
Taira TM, Lima V, Prado DS, Silva TA, Issa JPM, da Silva LAB, Zamboni DS, Cunha FQ, Fukada SY. NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis. Journal of Dental Research. 22034518820289. PMID 30681895 DOI: 10.1177/0022034518820289 |
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| 2019 |
Pinto LG, Souza GR, Kusuda R, Lopes AH, Sant'Anna MB, Cunha FQ, Ferreira SH, Cunha TM. Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice. Molecular Neurobiology. PMID 30674034 DOI: 10.1007/S12035-019-1494-5 |
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| 2019 |
Siervo GEML, Ogo FM, Staurengo-Ferrari L, Anselmo-Franci JA, Cunha FQ, Cecchini R, Guarnier FA, Verri WA, Fernandes GSA. Sleep restriction during peripuberty unbalances sexual hormones and testicular cytokines in rats. Biology of Reproduction. 100: 112-122. PMID 30010983 DOI: 10.1093/Biolre/Ioy161 |
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| 2018 |
Castanheira FVES, de Lima KA, Cebinelli GCM, Sônego F, Kanashiro A, Colon DF, Borges V, Czaikoski PG, Mota JM, Cunha TM, Alves-Filho JC, Liew FY, Cunha FQ. CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis. Shock (Augusta, Ga.). PMID 30724784 DOI: 10.1097/Shk.0000000000001301 |
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| 2018 |
Lima KAd, Donate PB, Talbot J, Davoli-Ferreira M, Peres RS, Cunha TM, Alves-Filho JC, Cunha FQ. TGFβ1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism. Cell Death and Disease. 9: 1130-1130. PMID 30425241 DOI: 10.1038/S41419-018-1107-7 |
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| 2018 |
Manchope MF, Artero NA, Fattori V, Mizokami SS, Pitol DL, Issa JPM, Fukada SY, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. Naringenin mitigates titanium dioxide (TiO)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 67: 997-1012. PMID 30370484 DOI: 10.1007/S00011-018-1195-Y |
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| 2018 |
Staurengo-Ferrari L, Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Fattori V, Zaninelli TH, Badaro-Garcia S, Borghi SM, Carvalho TT, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. -Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice. Frontiers in Pharmacology. 9: 1123. PMID 30333752 DOI: 10.3389/Fphar.2018.01123 |
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| 2018 |
Fattori V, Zarpelon AC, Staurengo-Ferrari L, Borghi SM, Zaninelli TH, Da Costa FB, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. Budlein A, a Sesquiterpene Lactone From , Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in Mice. Frontiers in Pharmacology. 9: 1076. PMID 30319413 DOI: 10.3389/Fphar.2018.01076 |
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| 2018 |
Ruiz-Miyazawa KW, Staurengo-Ferrari L, Pinho-Ribeiro FA, Fattori V, Zaninelli TH, Badaro-Garcia S, Borghi SM, Andrade KC, Clemente-Napimoga JT, Alves-Filho JC, Cunha TM, Fraceto LF, Cunha FQ, Napimoga MH, Casagrande R, et al. 15d-PGJ-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice. Scientific Reports. 8: 13979. PMID 30228306 DOI: 10.1038/S41598-018-32334-0 |
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| 2018 |
Ferreira RG, Rodrigues LC, Nascimento DC, Kanashiro A, Melo PH, Borges VF, Gozzi A, da Silva Prado D, Borges MC, Ramalho FS, Stowell SR, Cummings RD, Dias-Baruffi M, Cunha FQ, Alves-Filho JC. Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus. The Journal of Infection. PMID 30226191 DOI: 10.1016/J.Jinf.2018.06.010 |
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| 2018 |
Santa-Cecília FV, Ferreira DW, Guimaraes RM, Cecilio NT, Fonseca MM, Lopes AH, Davoli-Ferreira M, Kusuda R, Souza GR, Nachbur U, Alves-Filho JC, Teixeira MM, Zamboni DS, Cunha FQ, Cunha TM. The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development. Pain. PMID 30169421 DOI: 10.1097/J.Pain.0000000000001383 |
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| 2018 |
Wanderley CW, Colon DF, Luiz JPM, Oliveira FF, Viacava PR, Leite CA, Pereira JA, Silva CM, Silva CR, Silva RL, Speck-Hernandez CA, Mota JM, Alves-Filho JC, Lima-Júnior RC, Cunha TM, ... Cunha FQ, et al. Paclitaxel reduces tumor growth by reprogramming tumor-associated macrophages to an M1- profile in a TLR4-dependent manner. Cancer Research. PMID 30104241 DOI: 10.1158/0008-5472.Can-17-3480 |
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| 2018 |
Benevides L, Costa RS, Tavares LA, Russo M, Martins GA, da Silva LLP, Karla de P Arruda L, Cunha FQ, Carregaro V, Silva JS. Blimp-1 controls Th9 cell development, IL-9 production and allergic inflammation. The Journal of Allergy and Clinical Immunology. PMID 30096391 DOI: 10.1016/J.Jaci.2018.06.046 |
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| 2018 |
Dornelas-Filho AF, Pereira VBM, Wong DVT, Nobre LMS, Melo AT, Silva CMS, Wanderley CWS, Nour ML, Araújo LCNC, Silva RO, Pinto FMM, Bingana RD, Souza MHLP, Alencar NMN, Silva PGB, ... ... Cunha FQ, et al. Neutrophils contribute to the pathogenesis of hemorrhagic cystitis induced by ifosfamide. International Immunopharmacology. 62: 96-108. PMID 29990699 DOI: 10.1016/J.Intimp.2018.06.031 |
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| 2018 |
Saraiva AL, Veras FP, Peres RS, Talbot J, de Lima KA, Luiz JP, Carballido JM, Cunha TM, Cunha FQ, Ryffel B, Alves-Filho JC. Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T17 cells in the lymph nodes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800285. PMID 29894669 DOI: 10.1096/Fj.201800285 |
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| 2018 |
Staurengo-Ferrari L, Trevelin SC, Fattori V, Nascimento DC, de Lima KA, Pelayo JS, Figueiredo F, Casagrande R, Fukada SY, Teixeira MM, Cunha TM, Liew FY, Oliveira RD, Louzada-Junior P, Cunha FQ, et al. Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of -Induced Septic Arthritis. Frontiers in Immunology. 9: 962. PMID 29867945 DOI: 10.3389/Fimmu.2018.00962 |
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| 2018 |
Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Borghi SM, Staurengo-Ferrari L, Fattori V, Amaral F, Teixeira MM, Alves-Filho JCF, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Hesperidin methylchalcone suppresses experimental gout arthritis in mice by inhibiting NF-kB activation. Journal of Agricultural and Food Chemistry. PMID 29852732 DOI: 10.1021/Acs.Jafc.8B00959 |
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| 2018 |
Bassi GS, Kanashiro A, Rodrigues GJ, Cunha FQ, Coimbra NC, Ulloa L. Brain Stimulation Differentially Modulates Nociception and Inflammation in Aversive and Non-aversive Behavioral Conditions. Neuroscience. 383: 191-204. PMID 29772343 DOI: 10.1016/J.Neuroscience.2018.05.008 |
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| 2018 |
Sisti F, Wang S, Brandt SL, Glosson-Byers N, Mayo LD, Son YM, Sturgeon S, Filgueiras L, Jancar S, Wong H, Dela Cruz CS, Andrews N, Alves-Filho JC, Cunha FQ, Serezani CH. Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis. Science Signaling. 11. PMID 29717063 DOI: 10.1126/Scisignal.Aai9085 |
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| 2018 |
Silva MC, Davoli-Ferreira M, Medina TS, Sesti-Costa R, Silva GK, Lopes CD, Cardozo LE, Gava FN, Lyroni K, Dias FC, Frade AF, Baron M, Nakaya HI, Figueiredo F, Alves-Filho JC, ... Cunha FQ, et al. Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nature Communications. 9: 1513. PMID 29666415 DOI: 10.1038/S41467-018-03986-3 |
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| 2018 |
Bassi GS, Ulloa L, Santos VR, Del Vecchio F, Delfino-Pereira P, Rodrigues GJ, Castania JA, Cunha FQ, Salgado HC, Cunha TM, Garcia-Cairasco N, Kanashiro A. Cortical stimulation in conscious rats controls joint inflammation. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29522782 DOI: 10.1016/J.Pnpbp.2018.02.013 |
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| 2018 |
Peres RS, Donate PB, Talbot J, Cecilio NT, Lobo PR, Machado CC, Lima KWA, Oliveira RD, Carregaro V, Nakaya HI, Cunha TM, Alves-Filho JC, Liew FY, Louzada-Junior P, Cunha FQ. TGF-β signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis. Journal of Autoimmunity. PMID 29426578 DOI: 10.1016/J.Jaut.2018.01.004 |
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| 2018 |
Lisboa SF, Issy AC, Biojone C, Montezuma K, Fattori V, Del-Bel EA, Guimarães FS, Cunha FQ, Verri WA, Joca SRL. Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms. Journal of Neuroimmunology. 314: 58-66. PMID 29195684 DOI: 10.1016/J.Jneuroim.2017.11.008 |
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| 2018 |
Ruiz-Miyazawa KW, Borghi SM, Pinho-Ribeiro FA, Staurengo-Ferrari L, Fattori V, Fernandes GS, Casella AM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. The citrus flavanone naringenin reduces gout-induced joint pain and inflammation in mice by inhibiting the activation of NFκB and macrophage release of IL-1β Journal of Functional Foods. 48: 106-116. DOI: 10.1016/J.Jff.2018.06.025 |
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| 2017 |
Castanheira FVES, Borges V, Sônego F, Kanashiro A, Donate PB, Melo PH, Pallas K, Russo RC, Amaral FA, Teixeira MM, Ramalho FS, Cunha TM, Liew FY, Alves-Filho JC, Graham GJ, ... Cunha FQ, et al. The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis. Shock (Augusta, Ga.). PMID 29589840 DOI: 10.1097/Shk.0000000000000969 |
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| 2017 |
Azevedo PO, Sena IFG, Andreotti JP, Carvalho-Tavares J, Alves-Filho JC, Cunha TM, Cunha FQ, Mintz A, Birbrair A. Pericytes modulate myelination in the central nervous system. Journal of Cellular Physiology. PMID 29215724 DOI: 10.1002/Jcp.26348 |
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| 2017 |
Kanashiro A, Franchin M, Bassi GS, Reis Santana DA, Cunha TM, Cunha FQ, Ulloa L, Rodrigues GJ. Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation. Fundamental & Clinical Pharmacology. 32: 155-162. PMID 29206314 DOI: 10.1111/Fcp.12338 |
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| 2017 |
Fattori V, Hohmann MSN, Rossaneis AC, Manchope MF, Alves-Filho JC, Cunha TM, Cunha FQ, Verri WA. Targeting IL-33/ST2 signaling: regulation of immune function and analgesia. Expert Opinion On Therapeutic Targets. 21: 1141-1152. PMID 29076792 DOI: 10.1080/14728222.2017.1398734 |
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| 2017 |
Zarpelon AC, Fattori V, Souto FO, Pinto LG, Pinho-Ribeiro FA, Ruiz-Miyazawa KW, Turato WM, Cunha TM, Da Costa FB, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. Erratum to: The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines. Inflammation. PMID 28879563 DOI: 10.1007/s10753-017-0663-9 |
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| 2017 |
Zarpelon AC, Fattori V, Souto FO, Pinto LG, Pinho-Ribeiro FA, Ruiz-Miyazawa KW, Turato WM, Cunha TM, da Costa FB, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines. Inflammation. PMID 28780730 DOI: 10.1007/S10753-017-0642-1 |
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| 2017 |
Lima MHF, Sacramento LA, Quirino GFS, Ferreira MD, Benevides L, Santana AKM, Cunha FQ, Almeida RP, Silva JS, Carregaro V. Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2A Receptor to Promote the Establishment of Infection. Frontiers in Immunology. 8: 815. PMID 28775724 DOI: 10.3389/fimmu.2017.00815 |
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Santos-Almeida FM, Domingos-Souza G, Meschiari CA, Fávaro LC, Becari C, Castania JA, Lopes A, Cunha TM, Moraes DJA, Cunha FQ, Ulloa L, Kanashiro A, Tezini GCSV, Salgado HC. Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation. Scientific Reports. 7: 6265. PMID 28740186 DOI: 10.1038/s41598-017-06703-0 |
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Bertozzi MM, Rossaneis AC, Fattori V, Longhi-Balbinot DT, Freitas A, Cunha FQ, Alves-Filho JC, Cunha TM, Casagrande R, Verri WA. Diosmin reduces chronic constriction injury-induced neuropathic pain in mice. Chemico-Biological Interactions. 273: 180-189. PMID 28625489 DOI: 10.1016/J.Cbi.2017.06.014 |
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Silva JR, Lopes AH, Talbot J, Cecilio NT, Rossato MF, Silva RL, Souza GR, Silva CR, Lucas G, Fonseca BA, Arruda E, Alves-Filho JC, Cunha FQ, Cunha TM. Neuro-immune-glia interactions in the sensory ganglia account for the development of acute herpetic neuralgia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28576938 DOI: 10.1523/Jneurosci.2233-16.2017 |
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Dal-Secco D, DalBó S, Lautherbach NES, Gava FN, Celes MRN, Benedet PO, Souza AH, Akinaga J, Lima V, Silva KP, Kiguti LRA, Rossi MA, Kettelhut IDC, Pupo AS, Cunha FQ, et al. Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G-protein receptor kinase. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00052.2016. PMID 28526706 DOI: 10.1152/Ajpheart.00052.2016 |
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Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Pinho-Ribeiro FA, Zarpelon AC, Saraiva ALL, Cecílio TN, Alves-Filho JC, Cunha TM, Menezes GB, Cunha FQ, Casagrande R, Verri WA. Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production. European Journal of Pharmacology. PMID 28501577 DOI: 10.1016/j.ejphar.2017.05.016 |
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de Aquino SG, Talbot J, Sônego F, Turato WM, Grespan R, Avila-Campos MJ, Cunha FQ, Cirelli JA. The aggravation of arthritis by periodontitis is dependent of IL-17 receptor A activation. Journal of Clinical Periodontology. 44: 881-891. PMID 28498497 DOI: 10.1111/jcpe.12743 |
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Souza MC, Fonseca DM, Kanashiro A, Benevides L, Medina TS, Dias MS, Andrade WA, Bonfá G, Silva MAB, Gozzi A, Borges MC, Gazzinelli RT, Alves-Filho JC, Cunha FQ, Silva JS. Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis. Frontiers in Cellular and Infection Microbiology. 7: 116. PMID 28439500 DOI: 10.3389/Fcimb.2017.00116 |
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Bassi GS, Dias DP, Franchin M, Talbot J, Reis DG, Menezes GB, Castania JA, Garcia-Cairasco N, Resstel L, Salgado HC, Cunha FQ, Cunha TM, Ulloa L, Kanashiro A. Modulation of Experimental Arthritis by Vagal Sensory and Central Brain Stimulation. Brain, Behavior, and Immunity. PMID 28392428 DOI: 10.1016/J.Bbi.2017.04.003 |
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Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Alves-Filho JC, Cunha TM, Antunes MM, Menezes GB, Cunha FQ, Casagrande R, Verri WA. Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 28386622 DOI: 10.1007/S00011-017-1040-8 |
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Nascimento DC, Melo PH, Piñeros AR, Ferreira RG, Colón DF, Donate PB, Castanheira FV, Gozzi A, Czaikoski PG, Niedbala W, Borges MC, Zamboni DS, Liew FY, Cunha FQ, Alves-Filho JC. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nature Communications. 8: 14919. PMID 28374774 DOI: 10.1038/Ncomms14919 |
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Sacramento LA, da Costa JL, de Lima MH, Sampaio PA, Almeida RP, Cunha FQ, Silva JS, Carregaro V. Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection. Frontiers in Microbiology. 8: 262. PMID 28280488 DOI: 10.3389/Fmicb.2017.00262 |
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Peres RS, Santos GB, Cecilio NT, Jabor VA, Niehues M, Torres BG, Buqui G, Silva CH, Costa TD, Lopes NP, Nonato MC, Ramalho FS, Louzada-Júnior P, Cunha TM, Cunha FQ, et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. Arthritis Research & Therapy. 19: 47. PMID 28270195 DOI: 10.1186/S13075-017-1236-X |
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Fattori V, Serafim KG, Zarpelon AC, Borghi SM, Pinho-Ribeiro FA, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Differential regulation of oxidative stress and cytokine production by endothelin ET and ET receptors in superoxide anion-induced inflammation and pain in mice. Journal of Drug Targeting. 25: 264-274. PMID 27701898 DOI: 10.1080/1061186X.2016.1245308 |
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Fonseca MM, Santa-Cecilia F, Kusuda R, Ferreira D, Bezerra F, Ferreira M, Guimarães R, Cunha F, Cunha T. (153) The interleukin 27 (IL-27) protects mice from neuropathic pain development through up-regulation of anti-inflammatory cytokine IL-10 The Journal of Pain. 18. DOI: 10.1016/J.Jpain.2017.02.059 |
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Kanashiro A, Sônego F, Ferreira RG, Castanheira FV, Leite CA, Borges VF, Nascimento DC, Cólon DF, Alves-Filho JC, Ulloa L, Cunha FQ. Therapeutic Potential and Limitations of Cholinergic Anti-Inflammatory Pathway in Sepsis. Pharmacological Research. PMID 27979692 DOI: 10.1016/J.Phrs.2016.12.014 |
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Carregaro V, Napimoga MH, Peres RS, Benevides L, Sacramento LA, Pinto LG, Grespan R, Cunha TM, da Silva JS, Cunha FQ. Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ(12,14)-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators of Inflammation. 2016: 9626427. PMID 27872515 DOI: 10.1155/2016/9626427 |
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| 2016 |
Trevelin SC, Dos Santos CX, Ferreira RG, de Sá Lima L, Silva RL, Scavone C, Curi R, Alves-Filho JC, Cunha TM, Roxo-Júnior P, Cervi MC, Laurindo FR, Hothersall JS, Cobb AM, Zhang M, ... ... Cunha FQ, et al. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state. Scientific Reports. 6: 34581. PMID 27698473 DOI: 10.1038/Srep34581 |
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Guerrero AT, Pinto LG, Cunha FQ, Ferreira SH, Alves-Filho JC, Verri WA, Cunha TM. Mechanisms underlying the hyperalgesic responses triggered by joint activation of TLR4. Pharmacological Reports : Pr. 68: 1293-1300. PMID 27689757 DOI: 10.1016/J.Pharep.2016.08.006 |
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Franchin M, Rosalen PL, da Cunha MG, Silva RL, Colón DF, Bassi GS, de Alencar SM, Ikegaki M, Alves-Filho JC, Cunha FQ, Beutler JA, Cunha TM. Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB. Journal of Natural Products. PMID 27367493 DOI: 10.1021/Acs.Jnatprod.6B00263 |
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Franca RF, Costa RS, Silva JR, Peres RS, Mendonça LR, Colón DF, Alves-Filho JC, Cunha FQ. IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system. Journal of Neuroinflammation. 13: 159. PMID 27334012 DOI: 10.1186/S12974-016-0628-1 |
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Longhi-Balbinot DT, Rossaneis AC, Pinho-Ribeiro FA, Bertozzi MM, Cunha FQ, Alves-Filho JC, Cunha TM, Peron JP, Miranda KM, Casagrande R, Verri WA. The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain. Chemico-Biological Interactions. PMID 27287419 DOI: 10.1016/J.Cbi.2016.06.009 |
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Silva RL, Castanheira FV, Figueiredo JG, Bassi GS, Ferreira SH, Cunha FQ, Cunha TM, Kanashiro A. Pharmacological Beta-Adrenergic Receptor Activation Attenuates Neutrophil Recruitment by a Mechanism Dependent on Nicotinic Receptor and the Spleen. Inflammation. PMID 27262431 DOI: 10.1007/s10753-016-0372-9 |
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Pinho-Ribeiro FA, Zarpelon AC, Mizokami SS, Borghi SM, Bordignon J, Silva RL, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation. The Journal of Nutritional Biochemistry. 33: 8-14. PMID 27260463 DOI: 10.1016/J.Jnutbio.2016.03.013 |
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Sant'Anna MB, Kusuda R, Bozzo TA, Bassi GS, Alves-Filho JC, Cunha FQ, Ferreira SH, Souza GR, Cunha TM. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization. Scientific Reports. 6: 26955. PMID 27230787 DOI: 10.1038/Srep26955 |
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Sônego F, Castanheira FV, Ferreira RG, Kanashiro A, Leite CA, Nascimento DC, Colón DF, Borges Vde F, Alves-Filho JC, Cunha FQ. Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious. Frontiers in Immunology. 7: 155. PMID 27199981 DOI: 10.3389/Fimmu.2016.00155 |
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Pinho-Ribeiro FA, Fattori V, Zarpelon AC, Borghi SM, Staurengo-Ferrari L, Carvalho TT, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress. Inflammopharmacology. 24: 97-107. PMID 27160222 DOI: 10.1007/s10787-016-0266-3 |
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Bassi GS, do C Malvar D, Cunha TM, Cunha FQ, Kanashiro A. Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis. Naunyn-Schmiedeberg's Archives of Pharmacology. 389: 851-61. PMID 27106212 DOI: 10.1007/s00210-016-1248-0 |
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de Molon RS, Hsu C, Bezouglaia O, Dry SM, Pirih FQ, Soundia A, Cunha FQ, Cirelli JA, Aghaloo TL, Tetradis S. Rheumatoid Arthritis Exacerbates the Severity of Osteonecrosis of the Jaws (ONJ) in Mice. A Randomized, Prospective, Controlled Animal Study. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26950411 DOI: 10.1002/Jbmr.2827 |
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Santos SS, Carmo AM, Brunialti MK, Machado FR, Azevedo LC, Assunção M, Trevelin SC, Cunha FQ, Salomao R. Modulation of monocytes in septic patients: preserved phagocytic activity, increased ROS and NO generation, and decreased production of inflammatory cytokines. Intensive Care Medicine Experimental. 4: 5. PMID 26879814 DOI: 10.1186/S40635-016-0078-1 |
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Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis. Plos One. 11: e0148142. PMID 26849138 DOI: 10.1371/Journal.Pone.0148142 |
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Mota JM, Leite CA, Souza LE, Melo PH, Nascimento DC, de Deus Wagatsuma VM, Temporal J, Figueiredo F, Noushmehr H, Alves-Filho JC, Cunha FQ, Rego EM. Post-sepsis state induces tumor-associated macrophage accumulation through CXCR4/CXCL12 and favors tumor progression in mice. Cancer Immunology Research. PMID 26817997 DOI: 10.1158/2326-6066.Cir-15-0170 |
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Peres RS, Menezes GB, Teixeira MM, Cunha FQ. Pharmacological opportunities to control inflammatory diseases through inhibition of the leukocyte recruitment. Pharmacological Research. PMID 26808082 DOI: 10.1016/J.Phrs.2016.01.015 |
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Leite CA, Melo PH, Mota JM, Prado DS, Viacava PR, Cunha FQ, Filho JCA. Abstract 770: Negative regulation of the CCL22/CCR4 axis by TNFR1 improves melanoma outcome Cancer Research. 76: 770-770. DOI: 10.1158/1538-7445.Am2016-770 |
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Cellone Trevelin S, Santos C, Ferreira R, Lima L, Scavone C, Curi R, Carlos Alves-Filho J, Cunha T, Laurindo F, Shah A, Ivetic A, Cunha F, Rossetti Lopes L. NOX2 Regulates Inflammation by Modifying Thioredoxin-1 Redox State Free Radical Biology and Medicine. 100: S42. DOI: 10.1016/J.Freeradbiomed.2016.10.110 |
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Lopes AH, Brandolini L, Aramini A, Bianchini G, Silva RL, Zaperlon AC, Verri WA, Alves-Filho JC, Cunha FQ, Teixeira MM, Allegretti M, Cunha TM. DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain. Pharmacological Research. PMID 26592483 DOI: 10.1016/J.Phrs.2015.11.005 |
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Quadros AU, Pinto LG, Fonseca MM, Kusuda R, Cunha FQ, Cunha TM. Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice. Scientific Reports. 5: 14648. PMID 26511791 DOI: 10.1038/Srep14648 |
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Veras FP, Peres RS, Saraiva AL, Pinto LG, Louzada-Junior P, Cunha TM, Paschoal JA, Cunha FQ, Alves-Filho JC. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. Scientific Reports. 5: 15171. PMID 26478088 DOI: 10.1038/Srep15171 |
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Fattori V, Pinho-Ribeiro FA, Borghi SM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 64: 993-1003. PMID 26456836 DOI: 10.1007/S00011-015-0885-Y |
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Wong DV, Lima-Júnior RC, Carvalho CB, Borges VF, Wanderley CW, Bem AX, Leite CA, Teixeira MA, Batista GL, Silva RL, Cunha TM, Brito GA, Almeida PR, Cunha FQ, Ribeiro RA. The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis. Plos One. 10: e0139985. PMID 26440613 DOI: 10.1371/Journal.Pone.0139985 |
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Pinke KH, Lima HG, Cunha FQ, Lara VS. Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1. Immunobiology. 221: 220-7. PMID 26421959 DOI: 10.1016/J.Imbio.2015.09.004 |
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Sacramento L, Trevelin SC, Nascimento MS, Lima-Jùnior DS, Costa DL, Almeida RP, Cunha FQ, Silva JS, Carregaro V. Toll-Like Receptor 9 Signaling in Dendritic Cells Regulates Neutrophil Recruitment to Inflammatory Foci following Leishmania infantum Infection. Infection and Immunity. 83: 4604-16. PMID 26371124 DOI: 10.1128/Iai.00975-15 |
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Pinto LG, Talbot J, Peres RS, Franca RF, Ferreira SH, Ryffel B, Aves-Filho JC, Figueiredo F, Cunha TM, Cunha FQ. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy. 17: 235. PMID 26330334 DOI: 10.1186/S13075-015-0759-2 |
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Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, ... ... Cunha FQ, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26310268 DOI: 10.1096/Fj.14-267146 |
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Yamacita-Borin FY, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice. Neuroscience Letters. 605: 53-8. PMID 26291484 DOI: 10.1016/J.Neulet.2015.08.015 |
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Serafim KG, Navarro SA, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 26246053 DOI: 10.1007/S00210-015-1160-Z |
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Fonseca MD, Cunha FQ, Kashfi K, Cunha TM. NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain. Pharmacology Research & Perspectives. 3: e00133. PMID 26236481 DOI: 10.1002/Prp2.133 |
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Carlos D, Yaochite JN, Rocha FA, Toso VD, Malmegrim KC, Ramos SG, Jamur MC, Oliver C, Camara NO, Andrade MV, Cunha FQ, Silva JS. Mast cells control insulitis and increase Treg cells to confer protection against STZ-induced type 1 diabetes in mice. European Journal of Immunology. 45: 2873-85. PMID 26234742 DOI: 10.1002/Eji.201545498 |
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Leite CA, Alencar VT, Melo DL, Mota JM, Melo PH, Mourão LT, Wong DV, Magalhães PJ, Santos AA, Brito GA, Lima-Júnior RC, Cunha FQ, Ribeiro RA. Target Inhibition of IL-1 Receptor Prevents Ifosfamide Induced Hemorrhagic Cystitis in Mice. The Journal of Urology. PMID 26220217 DOI: 10.1016/J.Juro.2015.07.088 |
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Molinaro R, Pecli C, Guilherme RF, Alves-Filho JC, Cunha FQ, Canetti C, Kunkel SL, Bozza MT, Benjamim CF. CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis. Plos One. 10: e0133227. PMID 26197455 DOI: 10.1371/Journal.Pone.0133227 |
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Bassi GS, Brognara F, Castania JA, Talbot J, Cunha TM, Cunha FQ, Ulloa L, Kanashiro A, Dias DP, Salgado HC. Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. Brain, Behavior, and Immunity. 49: 140-7. PMID 25986215 DOI: 10.1016/j.bbi.2015.05.002 |
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Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Zarpelon AC, Staurengo-Ferrari L, Silva RL, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB. Chemico-Biological Interactions. 237: 9-17. PMID 25980587 DOI: 10.1016/J.Cbi.2015.05.007 |
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Freitas CS, Roveda AC, Truzzi DR, Garcia AC, Cunha TM, Cunha FQ, Franco DW. Anti-inflammatory and Anti-nociceptive Activity of Ruthenium Complexes with Isonicotinic and Nicotinic Acids (Niacin) as Ligands. Journal of Medicinal Chemistry. 58: 4439-48. PMID 25973517 DOI: 10.1021/Acs.Jmedchem.5B00133 |
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Parra RS, Lopes AH, Carreira EU, Feitosa MR, Cunha FQ, Garcia SB, Cunha TM, da Rocha JJ, Féres O. Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats. Medical Gas Research. 5: 6. PMID 25926972 DOI: 10.1186/S13618-015-0026-2 |
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Souza GR, Cunha TM, Silva RL, Lotufo CM, Verri WA, Funez MI, Villarreal CF, Talbot J, Sousa LP, Parada CA, Cunha FQ, Ferreira SH. Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception. Pharmacology, Biochemistry, and Behavior. 134: 49-56. PMID 25902407 DOI: 10.1016/J.Pbb.2015.04.005 |
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Carregaro V, Ribeiro JM, Valenzuela JG, Souza-Júnior DL, Costa DL, Oliveira CJ, Sacramento LA, Nascimento MS, Milanezi CM, Cunha FQ, Silva JS. Nucleosides present on phlebotomine saliva induce immunossuppression and promote the infection establishment. Plos Neglected Tropical Diseases. 9: e0003600. PMID 25849562 DOI: 10.1371/Journal.Pntd.0003600 |
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| 2015 |
Talbot J, Bianchini FJ, Nascimento DC, Oliveira RD, Souto FO, Pinto LG, Peres RS, Silva JR, Almeida SC, Louzada-Junior P, Cunha TM, Cunha FQ, Alves-Filho JC. CCR2 Expression in Neutrophils Plays a Critical Role in Their Migration Into the Joints in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1751-9. PMID 25779331 DOI: 10.1002/Art.39117 |
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Bastos Moura JF, Mota JM, Leite CA, Wong DV, Bezerra NP, Brito GA, Lima V, Cunha FQ, Ribeiro RA. A novel model of megavoltage radiation-induced oral mucositis in hamsters: Role of inflammatory cytokines and nitric oxide. International Journal of Radiation Biology. 91: 500-9. PMID 25758466 DOI: 10.3109/09553002.2015.1021964 |
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Borghi SM, Pinho-Ribeiro FA, Zarpelon AC, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice. Experimental Physiology. 100: 531-44. PMID 25711612 DOI: 10.1113/Ep085026 |
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Lopes AH, Talbot J, Silva RL, Lima JB, França RO, Verri WA, Mascarenhas DP, Ryffel B, Cunha FQ, Zamboni DS, Cunha TM. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain. 156: 451-9. PMID 25687541 DOI: 10.1097/01.J.Pain.0000460322.72396.53 |
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Peres RS, Liew FY, Talbot J, Carregaro V, Oliveira RD, Almeida SL, França RF, Donate PB, Pinto LG, Ferreira FI, Costa DL, Demarque DP, Gouvea DR, Lopes NP, Queiroz RH, ... ... Cunha FQ, et al. Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2509-14. PMID 25675517 DOI: 10.1073/Pnas.1424792112 |
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Silva RL, Lopes AH, França RO, Vieira SM, Silva EC, Amorim RC, Cunha FQ, Pohlit AM, Cunha TM. The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation. Journal of Natural Products. 78: 241-9. PMID 25667960 DOI: 10.1021/Np500796F |
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Conte FP, Ferraris FK, Costa TE, Pacheco P, Seito LN, Verri WA, Cunha FQ, Penido C, Henriques MG. Effect of gedunin on acute articular inflammation and hypernociception in mice. Molecules (Basel, Switzerland). 20: 2636-57. PMID 25654532 DOI: 10.3390/Molecules20022636 |
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| 2015 |
Lisboa SF, Gomes FV, Silva AL, Uliana DL, Camargo LH, Guimarães FS, Cunha FQ, Joca SR, Resstel LB. Increased Contextual Fear Conditioning in iNOS Knockout Mice: Additional Evidence for the Involvement of Nitric Oxide in Stress-Related Disorders and Contribution of the Endocannabinoid System. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25618404 DOI: 10.1093/Ijnp/Pyv005 |
0.322 |
|
| 2015 |
Carvalho TT, Borghi SM, Pinho-Ribeiro FA, Mizokami SS, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10. European Journal of Pharmacology. 749: 62-72. PMID 25584775 DOI: 10.1016/J.Ejphar.2014.12.023 |
0.792 |
|
| 2015 |
Segundo Correia Mota JM, Leite CA, Sousa LE, Wagatsuma VM, Noushmehr H, Cunha FQ, Rego EM. Effect of tumor-associated macrophages on neoplastic progression in sepsis-surviving mice through CXCL12/CXCR4. Journal of Clinical Oncology. 33: e22107-e22107. DOI: 10.1200/Jco.2015.33.15_Suppl.E22107 |
0.302 |
|
| 2014 |
Moriconi A, Cunha TM, Souza GR, Lopes AH, Cunha FQ, Carneiro VL, Pinto LG, Brandolini L, Aramini A, Bizzarri C, Bianchini G, Beccari AR, Fanton M, Bruno A, Costantino G, et al. Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief. Proceedings of the National Academy of Sciences of the United States of America. 111: 16937-42. PMID 25385614 DOI: 10.1073/Pnas.1417365111 |
0.737 |
|
| 2014 |
Sacramento LA, Cunha FQ, de Almeida RP, da Silva JS, Carregaro V. Protective role of 5-lipoxigenase during Leishmania infantum infection is associated with Th17 subset. Biomed Research International. 2014: 264270. PMID 25309905 DOI: 10.1155/2014/264270 |
0.301 |
|
| 2014 |
Prates TP, Taira TM, Holanda MC, Bignardi LA, Salvador SL, Zamboni DS, Cunha FQ, Fukada SY. NOD2 contributes to porphyromonas gingivalis-induced bone resorption Journal of Dental Research. 93: 1155-1162. PMID 25239844 DOI: 10.1177/0022034514551770 |
0.34 |
|
| 2014 |
Canavaci AM, Sorgi CA, Martins VP, Morais FR, de Sousa ÉV, Trindade BC, Cunha FQ, Rossi MA, Aronoff DM, Faccioli LH, Nomizo A. The acute phase of Trypanosoma cruzi infection is attenuated in 5-lipoxygenase-deficient mice. Mediators of Inflammation. 2014: 893634. PMID 25165415 DOI: 10.1155/2014/893634 |
0.406 |
|
| 2014 |
Wanderley CW, Silva CM, Wong DV, Ximenes RM, Morelo DF, Cosker F, Aragão KS, Fernandes C, Palheta-Júnior RC, Havt A, Brito GA, Cunha FQ, Ribeiro RA, Lima-Júnior RC. Bothrops jararacussu snake venom-induces a local inflammatory response in a prostanoid- and neutrophil-dependent manner. Toxicon : Official Journal of the International Society On Toxinology. 90: 134-47. PMID 25127849 DOI: 10.1016/J.Toxicon.2014.08.001 |
0.482 |
|
| 2014 |
Saia RS, Mestriner FL, Bertozi G, Cunha FQ, Cárnio EC. Cholecystokinin inhibits inducible nitric oxide synthase expression by lipopolysaccharide-stimulated peritoneal macrophages. Mediators of Inflammation. 2014: 896029. PMID 25125801 DOI: 10.1155/2014/896029 |
0.401 |
|
| 2014 |
Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response. Plos One. 9: e103734. PMID 25084278 DOI: 10.1371/Journal.Pone.0103734 |
0.435 |
|
| 2014 |
Staurengo-Ferrari L, Zarpelon AC, Longhi-Balbinot DT, Marchesi M, Cunha TM, Alves-Filho JC, Cunha FQ, Ferreira SH, Casagrande R, Miranda KM, Verri WA. Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway. Pharmacological Reports : Pr. 66: 691-8. PMID 24948073 DOI: 10.1016/J.Pharep.2014.04.003 |
0.76 |
|
| 2014 |
Barragán-Iglesias P, Rocha-González HI, Pineda-Farias JB, Murbartián J, Godínez-Chaparro B, Reinach PS, Cunha TM, Cunha FQ, Granados-Soto V. Inhibition of peripheral anion exchanger 3 decreases formalin-induced pain. European Journal of Pharmacology. 738: 91-100. PMID 24877687 DOI: 10.1016/J.Ejphar.2014.05.029 |
0.565 |
|
| 2014 |
Sônego F, Alves-Filho JC, Cunha FQ. Targeting neutrophils in sepsis. Expert Review of Clinical Immunology. 10: 1019-28. PMID 24867165 DOI: 10.1586/1744666X.2014.922876 |
0.363 |
|
| 2014 |
Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Targeting interleukin-1β reduces intense acute swimming-induced muscle mechanical hyperalgesia in mice. The Journal of Pharmacy and Pharmacology. 66: 1009-20. PMID 24697255 DOI: 10.1111/Jphp.12226 |
0.769 |
|
| 2014 |
de Aquino SG, Abdollahi-Roodsaz S, Koenders MI, van de Loo FA, Pruijn GJ, Marijnissen RJ, Walgreen B, Helsen MM, van den Bersselaar LA, de Molon RS, Avila Campos MJ, Cunha FQ, Cirelli JA, van den Berg WB. Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response. Journal of Immunology (Baltimore, Md. : 1950). 192: 4103-11. PMID 24683190 DOI: 10.4049/jimmunol.1301970 |
0.313 |
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| 2014 |
Calil IL, Zarpelon AC, Guerrero AT, Alves-Filho JC, Ferreira SH, Cunha FQ, Cunha TM, Verri WA. Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw. Plos One. 9: e90013. PMID 24595131 DOI: 10.1371/Journal.Pone.0090013 |
0.808 |
|
| 2014 |
Vieira SM, Silva RL, Lemos HP, Amorim RC, Silva EC, Reinach PS, Cunha FQ, Pohlit AM, Cunha TM. Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei. Fitoterapia. 95: 8-15. PMID 24594240 DOI: 10.1016/J.Fitote.2014.02.008 |
0.62 |
|
| 2014 |
Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Martins-Pinge MC, Tatakihara RI, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Role of TNF-α/TNFR1 in intense acute swimming-induced delayed onset muscle soreness in mice. Physiology & Behavior. 128: 277-87. PMID 24518865 DOI: 10.1016/J.Physbeh.2014.01.023 |
0.764 |
|
| 2014 |
Ferreira AE, Sisti F, Sônego F, Wang S, Filgueiras LR, Brandt S, Serezani AP, Du H, Cunha FQ, Alves-Filho JC, Serezani CH. PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 192: 2357-65. PMID 24489087 DOI: 10.4049/Jimmunol.1302375 |
0.471 |
|
| 2014 |
Lima-Júnior RC, Freitas HC, Wong DV, Wanderley CW, Nunes LG, Leite LL, Miranda SP, Souza MH, Brito GA, Magalhães PJ, Teixeira MM, Cunha FQ, Ribeiro RA. Targeted inhibition of IL-18 attenuates irinotecan-induced intestinal mucositis in mice. British Journal of Pharmacology. 171: 2335-50. PMID 24428790 DOI: 10.1111/Bph.12584 |
0.429 |
|
| 2014 |
Guabiraba R, Besnard AG, Menezes GB, Secher T, Jabir MS, Amaral SS, Braun H, Lima-Junior RC, Ribeiro RA, Cunha FQ, Teixeira MM, Beyaert R, Graham GJ, Liew FY. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunology. 7: 1079-93. PMID 24424522 DOI: 10.1038/Mi.2013.124 |
0.403 |
|
| 2014 |
Gutierrez FR, Pavanelli WR, Medina TS, Silva GK, Mariano FS, Guedes PM, Mineo TW, Rossi MA, Cunha FQ, Silva JS. Haeme oxygenase activity protects the host against excessive cardiac inflammation during experimental Trypanosoma cruzi infection. Microbes and Infection / Institut Pasteur. 16: 28-39. PMID 24140555 DOI: 10.1016/J.Micinf.2013.10.007 |
0.713 |
|
| 2014 |
Carmona F, Manso PH, Silveira VS, Cunha FQ, de Castro M, Carlotti AP. Inflammation, myocardial dysfunction, and mortality in children with septic shock: an observational study. Pediatric Cardiology. 35: 463-70. PMID 24091885 DOI: 10.1007/S00246-013-0801-6 |
0.318 |
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| 2014 |
Moriconi A, Cunha TM, Souza GR, Lopes AH, Cunha FQ, Carneiro VL, Pinto LG, Brandolini L, Aramini A, Bizzarri C, Bianchini G, Beccari AR, Fanton M, Bruno A, Costantino G, et al. Correction: Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief (Proc Natl Acad Sci USA (2014) 111, 47, (16937-16942) DOI: 10.1073/pnas.1417365111) Proceedings of the National Academy of Sciences of the United States of America. 111: 18799. DOI: 10.1073/Pnas.1422166112 |
0.322 |
|
| 2013 |
de Luca B, Xavier-Elsas P, Barradas M, Luz RA, Queto T, Jones C, Arruda MA, Cunha TM, Cunha FQ, Gaspar-Elsas MI. Essential roles of PKA, iNOS, CD95/CD95L, and terminal caspases in suppression of eosinopoiesis by PGE2 and other cAMP-elevating agents. Thescientificworldjournal. 2013: 208705. PMID 24376378 DOI: 10.1155/2013/208705 |
0.596 |
|
| 2013 |
Hohmann MS, Cardoso RD, Pinho-Ribeiro FA, Crespigio J, Cunha TM, Alves-Filho JC, da Silva RV, Pinge-Filho P, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed Research International. 2013: 627046. PMID 24288682 DOI: 10.1155/2013/627046 |
0.732 |
|
| 2013 |
Magro DA, Hohmann MS, Mizokami SS, Cunha TM, Alves-Filho JC, Casagrande R, Ferreira SH, Liew FY, Cunha FQ, Verri WA. An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 46: 601-6. PMID 23903682 DOI: 10.1590/1414-431X20132894 |
0.421 |
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| 2013 |
Carlos D, Spiller F, Souto FO, Trevelin SC, Borges VF, de Freitas A, Alves-Filho JC, Silva JS, Ryffel B, Cunha FQ. Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model. Journal of Immunology (Baltimore, Md. : 1950). 191: 1373-82. PMID 23817413 DOI: 10.4049/Jimmunol.1202907 |
0.519 |
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| 2013 |
Souza GR, Talbot J, Lotufo CM, Cunha FQ, Cunha TM, Ferreira SH. Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 11193-8. PMID 23776243 DOI: 10.1073/Pnas.1307445110 |
0.772 |
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| 2013 |
Vercelino R, Cunha TM, Ferreira ES, Cunha FQ, Ferreira SH, de Oliveira MG. Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel. Journal of Materials Science. Materials in Medicine. 24: 2157-69. PMID 23756965 DOI: 10.1007/S10856-013-4973-7 |
0.705 |
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| 2013 |
Carregaro V, Costa DL, Brodskyn C, Barral AM, Barral-Netto M, Cunha FQ, Silva JS. Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct saliva-induced cellular recruitment into BALB/c mice ear. Bmc Microbiology. 13: 102. PMID 23656976 DOI: 10.1186/1471-2180-13-102 |
0.519 |
|
| 2013 |
Zarpelon AC, Souza GR, Cunha TM, Schivo IR, Marchesi M, Casagrande R, Pinge-Filho P, Cunha FQ, Ferreira SH, Miranda KM, Verri WA. The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacology. 71: 1-9. PMID 23541720 DOI: 10.1016/J.Neuropharm.2013.03.009 |
0.799 |
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| 2013 |
Czaikoski PG, Nascimento DC, Sônego F, de Freitas A, Turato WM, de Carvalho MA, Santos RS, de Oliveira GP, dos Santos Samary C, Tefe-Silva C, Alves-Filho JC, Ferreira SH, Rossi MA, Rocco PR, Spiller F, ... Cunha FQ, et al. Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis. Shock (Augusta, Ga.). 39: 389-96. PMID 23481491 DOI: 10.1097/Shk.0B013E31828Bbcf9 |
0.62 |
|
| 2013 |
Tristão FS, Rocha FA, Moreira AP, Cunha FQ, Rossi MA, Silva JS. 5-Lipoxygenase activity increases susceptibility to experimental Paracoccidioides brasiliensis infection. Infection and Immunity. 81: 1256-66. PMID 23381993 DOI: 10.1128/Iai.01209-12 |
0.543 |
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| 2013 |
Donate PB, Fornari TA, Macedo C, Cunha TM, Nascimento DC, Sakamoto-Hojo ET, Donadi EA, Cunha FQ, Passos GA. T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis. Plos One. 8: e54803. PMID 23359619 DOI: 10.1371/journal.pone.0054803 |
0.422 |
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| 2013 |
Zarpelon AC, Cunha TM, Alves-Filho JC, Pinto LG, Ferreira SH, McInnes IB, Xu D, Liew FY, Cunha FQ, Verri WA. IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. British Journal of Pharmacology. 169: 90-101. PMID 23347081 DOI: 10.1111/Bph.12110 |
0.488 |
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| 2013 |
Saia RS, Bertozi G, Mestriner FL, Antunes-Rodrigues J, Cunha FQ, Cárnio EC. Cardiovascular and inflammatory response to cholecystokinin during endotoxemic shock. Shock. 39: 104-113. PMID 23247127 DOI: 10.1097/Shk.0B013E3182793E2E |
0.436 |
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| 2013 |
Guerrero AT, Zarpelon AC, Zaperlon AC, Vieira SM, Pinto LG, Ferreira SH, Cunha FQ, Verri WA, Cunha TM. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg's Archives of Pharmacology. 386: 51-9. PMID 23187752 DOI: 10.1007/S00210-012-0813-4 |
0.806 |
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| 2013 |
Yaochite JN, Caliari-Oliveira C, Davanso MR, Carlos D, Malmegrim KC, Cardoso CR, Ramalho LN, Palma PV, da Silva JS, Cunha FQ, Covas DT, Voltarelli JC. Dynamic changes of the Th17/Tc17 and regulatory T cell populations interfere in the experimental autoimmune diabetes pathogenesis. Immunobiology. 218: 338-52. PMID 22704522 DOI: 10.1016/J.Imbio.2012.05.010 |
0.376 |
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| 2013 |
D'Avila JC, Hernandes MS, Trevelin SC, Reis PA, Castro-Faria-Neto H, Cunha FQ, Britto LR, Bozza FA. Role of NOX2-derived ROS in the development of cognitive impairment after sepsis Critical Care. 17: 97. DOI: 10.1186/Cc12996 |
0.338 |
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| 2013 |
Lima LRd, Souza AH, Cunha FQ, Cavalcante CB, Teixeira MM, Faleiros RR. Reparixin, an antagonist of CXCR1/2, inhibits CXCL8-induced equine neutrophil migration Journal of Equine Veterinary Science. 33: 860-861. DOI: 10.1016/J.Jevs.2013.08.037 |
0.391 |
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| 2013 |
Guerrero AT, Zarpelon AC, Vieira SM, Pinto LG, Ferreira SH, Cunha FQ, Verri WA, Cunha TM. Erratum to: The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia Naunyn-Schmiedeberg's Archives of Pharmacology. 386: 351-351. DOI: 10.1007/S00210-012-0827-Y |
0.403 |
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| 2012 |
Cangussú SD, Souza CC, Castro MS, Vieira LQ, Cunha FQ, Afonso LC, Arantes RM. The endogenous cytokine profile and nerve fibre density in mouse ear Leishmania major-induced lesions related to nociceptive thresholds. Experimental Parasitology. 133: 193-200. PMID 23206953 DOI: 10.1016/j.exppara.2012.11.015 |
0.333 |
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| 2012 |
Carreira EU, Carregaro V, Teixeira MM, Moriconi A, Aramini A, Verri WA, Ferreira SH, Cunha FQ, Cunha TM. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. European Journal of Pain (London, England). 17: 654-63. PMID 23132735 DOI: 10.1002/J.1532-2149.2012.00240.X |
0.376 |
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| 2012 |
Soares PM, Mota JM, Souza EP, Justino PF, Franco AX, Cunha FQ, Ribeiro RA, Souza MH. Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4. Cytokine. 61: 46-9. PMID 23107827 DOI: 10.1016/J.Cyto.2012.10.003 |
0.437 |
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| 2012 |
Leoratti FM, Trevelin SC, Cunha FQ, Rocha BC, Costa PA, Gravina HD, Tada MS, Pereira DB, Golenbock DT, Antonelli LR, Gazzinelli RT. Neutrophil paralysis in Plasmodium vivax malaria. Plos Neglected Tropical Diseases. 6: e1710. PMID 22745844 DOI: 10.1371/Journal.Pntd.0001710 |
0.402 |
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| 2012 |
Trevelin SC, Alves-Filho JC, Sônego F, Turato W, Nascimento DC, Souto FO, Cunha TM, Gazzinelli RT, Cunha FQ. Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome. Critical Care Medicine. 40: 2631-7. PMID 22732279 DOI: 10.1097/CCM.0b013e318258fb70 |
0.504 |
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| 2012 |
de Oliveira Lopes R, Romeiro NC, de Lima CK, Louback da Silva L, de Miranda AL, Nascimento PG, Cunha FQ, Barreiro EJ, Lima LM. Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors. European Journal of Medicinal Chemistry. 54: 264-71. PMID 22647219 DOI: 10.1016/J.Ejmech.2012.05.006 |
0.356 |
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| 2012 |
Mizokami SS, Arakawa NS, Ambrosio SR, Zarpelon AC, Casagrande R, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Journal of Natural Products. 75: 896-904. PMID 22574649 DOI: 10.1021/Np200989T |
0.801 |
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| 2012 |
Junqueira C, Guerrero AT, Galvão-Filho B, Andrade WA, Salgado AP, Cunha TM, Ropert C, Campos MA, Penido ML, Mendonça-Previato L, Previato JO, Ritter G, Cunha FQ, Gazzinelli RT. Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine. Plos One. 7: e36245. PMID 22567144 DOI: 10.1371/Journal.Pone.0036245 |
0.549 |
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| 2012 |
Vieira SM, Cunha TM, França RF, Pinto LG, Talbot J, Turato WM, Lemos HP, Lima JB, Verri WA, Almeida SC, Ferreira SH, Louzada-Junior P, Zamboni DS, Cunha FQ. Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5116-22. PMID 22491249 DOI: 10.4049/Jimmunol.1004190 |
0.8 |
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| 2012 |
Spiller F, Carlos D, Souto FO, de Freitas A, Soares FS, Vieira SM, Paula FJ, Alves-Filho JC, Cunha FQ. α1-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice. Diabetes. 61: 1584-91. PMID 22415874 DOI: 10.2337/Db11-0825 |
0.338 |
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| 2012 |
Grespan R, Lemos HP, Carregaro V, Verri WA, Souto FO, de Oliveira CJ, Teixeira C, Ribeiro JM, Valenzuela JG, Cunha FQ. The protein LJM 111 from Lutzomyia longipalpis salivary gland extract (SGE) accounts for the SGE-inhibitory effects upon inflammatory parameters in experimental arthritis model. International Immunopharmacology. 12: 603-10. PMID 22366405 DOI: 10.1016/J.Intimp.2012.02.004 |
0.641 |
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| 2012 |
Santiago HC, Gonzalez Lombana CZ, Macedo JP, Utsch L, Tafuri WL, Campagnole-Santos MJ, Alves RO, Alves-Filho JC, Romanha AJ, Cunha FQ, Teixeira MM, Radi R, Vieira LQ. NADPH phagocyte oxidase knockout mice control Trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection. Plos Neglected Tropical Diseases. 6: e1492. PMID 22348160 DOI: 10.1371/Journal.Pntd.0001492 |
0.325 |
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| 2012 |
Zarpelon AC, Pinto LG, Cunha TM, Vieira SM, Carregaro V, Souza GR, Silva JS, Ferreira SH, Cunha FQ, Verri WA. Endothelin-1 induces neutrophil recruitment in adaptive inflammation via TNFα and CXCL1/CXCR2 in mice. Canadian Journal of Physiology and Pharmacology. 90: 187-99. PMID 22320712 DOI: 10.1139/Y11-116 |
0.795 |
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| 2012 |
Cunha TM, Souza GR, Domingues AC, Carreira EU, Lotufo CM, Funez MI, Verri WA, Cunha FQ, Ferreira SH. Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway. Molecular Pain. 8: 10. PMID 22316281 DOI: 10.1186/1744-8069-8-10 |
0.806 |
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| 2012 |
Pavao-de-Souza GF, Zarpelon AC, Tedeschi GC, Mizokami SS, Sanson JS, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice. Pharmacology, Biochemistry, and Behavior. 101: 320-8. PMID 22306747 DOI: 10.1016/J.Pbb.2012.01.018 |
0.758 |
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| 2012 |
Donate PB, Cunha TM, Verri WA, Junta CM, Lima FO, Vieira SM, Peres RS, Bombonato-Prado KF, Louzada P, Ferreira SH, Donadi EA, Passos GA, Cunha FQ. Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 61: 337-48. PMID 22249931 DOI: 10.1007/S00011-011-0415-5 |
0.781 |
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| 2012 |
Lima-Júnior RC, Figueiredo AA, Freitas HC, Melo ML, Wong DV, Leite CA, Medeiros RP, Marques-Neto RD, Vale ML, Brito GA, Oriá RB, Souza MH, Cunha FQ, Ribeiro RA. Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation. Cancer Chemotherapy and Pharmacology. 69: 931-42. PMID 22101361 DOI: 10.1007/S00280-011-1780-Z |
0.362 |
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| 2012 |
Guerrero AT, Cunha TM, Verri WA, Gazzinelli RT, Teixeira MM, Cunha FQ, Ferreira SH. Toll-like receptor 2/MyD88 signaling mediates zymosan-induced joint hypernociception in mice: participation of TNF-α, IL-1β and CXCL1/KC. European Journal of Pharmacology. 674: 51-7. PMID 22051147 DOI: 10.1016/J.Ejphar.2011.10.023 |
0.807 |
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| 2012 |
Brando Lima AC, Machado AL, Simon P, Cavalcante MM, Rezende DC, Sperandio da Silva GM, Nascimento PG, Quintas LE, Cunha FQ, Barreiro EJ, Lima LM, Koatz VL. Anti-inflammatory effects of LASSBio-998, a new drug candidate designed to be a p38 MAPK inhibitor, in an experimental model of acute lung inflammation. Pharmacological Reports : Pr. 63: 1029-39. PMID 22001991 DOI: 10.1016/S1734-1140(11)70619-3 |
0.418 |
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| 2012 |
Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis and Rheumatism. 64: 474-84. PMID 21952942 DOI: 10.1002/Art.33355 |
0.778 |
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| 2012 |
Montezuma K, Biojone C, Lisboa SF, Cunha FQ, Guimarães FS, Joca SR. Inhibition of iNOS induces antidepressant-like effects in mice: pharmacological and genetic evidence. Neuropharmacology. 62: 485-91. PMID 21939674 DOI: 10.1016/J.Neuropharm.2011.09.004 |
0.401 |
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| 2012 |
Soares DM, Figueiredo MJ, Martins JM, Machado RR, Sorgi C, Faciolli LH, Alves-Filho JC, Cunha FQ, Souza GE. A crucial role for IL-6 in the CNS of rats during fever induced by the injection of live E. coli. Medical Microbiology and Immunology. 201: 47-60. PMID 21643979 DOI: 10.1007/S00430-011-0204-3 |
0.415 |
|
| 2012 |
Macedo FY, Mourão LT, Freitas HC, Lima RC, Wong DV, Oriá RB, Vale ML, Brito GA, Cunha FQ, Ribeiro RA. Interleukin-4 modulates the inflammatory response in ifosfamide-induced hemorrhagic cystitis. Inflammation. 35: 297-307. PMID 21468627 DOI: 10.1007/S10753-011-9319-3 |
0.428 |
|
| 2012 |
Tavares-Murta BM, Cunha FQ, Dias-Baruffi M, Roque-Barreira MC, Ferreira SH. Macrophage-derived neutrophil chemotactic factor is involved in the neutrophil recruitment inhibitory activity present in the supernatants of LPS-stimulated macrophages. Mediators of Inflammation. 5: 116-20. PMID 18475709 DOI: 10.1155/S0962935196000208 |
0.395 |
|
| 2012 |
Dias-Baruffi M, Roque-Barreira MC, Cunha FQ, Ferreira SH. Biological characterization of purified macrophage-derived neutrophil chemotactic factor. Mediators of Inflammation. 4: 263-9. PMID 18475649 DOI: 10.1155/S0962935195000421 |
0.444 |
|
| 2012 |
Dias-Baruffi M, Roque-Barreira MC, Cunha FQ, Ferreira SH. Isolation and partial chemical characterization of macrophage-derived neutrophil chemotactic factor. Mediators of Inflammation. 4: 257-62. PMID 18475648 DOI: 10.1155/S096293519500041X |
0.363 |
|
| 2012 |
Fierro IM, Barja-Fidalgo C, Canedo RM, Cunha FQ, Ferreira SH. An increase in nitric oxide produced by rat peritoneal neutrophils is not involved in cell apoptosis. Mediators of Inflammation. 4: 222-8. PMID 18475643 DOI: 10.1155/S0962935195000366 |
0.32 |
|
| 2012 |
Ribeiro RA, Lucca FL, Flores CA, Cunha FQ, Ferreira SH. RNA from LPS-stirnulated macrophages induces the release of tumour necrosis factor-alpha and interleukin-1 by resident macrophages. Mediators of Inflammation. 2: 435-42. PMID 18475560 DOI: 10.1155/S0962935193000626 |
0.377 |
|
| 2012 |
Cunha FQ, Tamashiro WM. Tumour necrosis factor-alpha and interleukin-8 inhibit neutrophil migration in vitro and in vivo. Mediators of Inflammation. 1: 397-401. PMID 18475491 DOI: 10.1155/S0962935192000607 |
0.362 |
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| 2012 |
Tamashiro WM, Tavares-Murta BM, Cunha FQ, Roque-Barreira MC, Nogueira RM, Ferreira SH. Neutrophil recruitment inhibitory factor: a possible candidate for a novel cytokine. Mediators of Inflammation. 1: 49-54. PMID 18475441 DOI: 10.1155/S0962935192000103 |
0.462 |
|
| 2012 |
Heluy-Neto NE, Cunha FQ, Ferreira SH. In vivo Mononuclear Phagocyte Migration: Paradoxical Effect of Adrenalectomy. Mediators of Inflammation. 3: 275-9. PMID 18472952 DOI: 10.1155/S0962935194000372 |
0.37 |
|
| 2012 |
Thomazzi SM, Ribeiro RA, Campos DI, Cunha FQ, Ferreira SH. Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages. Mediators of Inflammation. 6: 195-200. PMID 18472820 DOI: 10.1080/09629359791686 |
0.478 |
|
| 2012 |
Abdollahi-Roodsaz S, de Aquino SG, Koenders M, Marijnissen R, Walgreen B, Helsen M, van den Bersselaar L, Cunha F, Cirelli J, van den Berg W. Periodontal pathogens amplify arthritic bone erosion by reducing the TH2 response and promoting a toll-like receptor 2-dependent TH17 phenotype Annals of the Rheumatic Diseases. 71: A28.1-A28. DOI: 10.1136/Annrheumdis-2011-201232.6 |
0.416 |
|
| 2012 |
Verri WA, Vicentini FTMC, Baracat MM, Georgetti SR, Cardoso RDR, Cunha TM, Ferreira SH, Cunha FQ, Fonseca MJV, Casagrande R. Chapter 9 – Flavonoids as Anti-Inflammatory and Analgesic Drugs: Mechanisms of Action and Perspectives in the Development of Pharmaceutical Forms Studies in Natural Products Chemistry. 36: 297-330. DOI: 10.1016/B978-0-444-53836-9.00026-8 |
0.385 |
|
| 2011 |
Gasparoto TH, de Oliveira CE, Vieira NA, Porto VC, Cunha FQ, Garlet GP, Campanelli AP, Lara VS. Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 31: 1271-7. PMID 22120419 DOI: 10.1007/S10096-011-1439-Z |
0.335 |
|
| 2011 |
Pinheiro BG, Silva AS, Souza GE, Figueiredo JG, Cunha FQ, Lahlou S, da Silva JK, Maia JG, Sousa PJ. Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud. Journal of Ethnopharmacology. 138: 479-86. PMID 21971207 DOI: 10.1016/J.Jep.2011.09.037 |
0.408 |
|
| 2011 |
Oliveira PG, Grespan R, Pinto LG, Meurer L, Brenol JC, Roesler R, Schwartsmann G, Cunha FQ, Xavier RM. Protective effect of RC-3095, an antagonist of the gastrin-releasing peptide receptor, in experimental arthritis. Arthritis and Rheumatism. 63: 2956-65. PMID 21953084 DOI: 10.1002/Art.30486 |
0.364 |
|
| 2011 |
Carregaro V, Sá-Nunes A, Cunha TM, Grespan R, Oliveira CJ, Lima-Junior DS, Costa DL, Verri WA, Milanezi CM, Pham VM, Brand DD, Valenzuela JG, Silva JS, Ribeiro JM, Cunha FQ. Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions. Journal of Immunology (Baltimore, Md. : 1950). 187: 4347-59. PMID 21930966 DOI: 10.4049/Jimmunol.1003404 |
0.754 |
|
| 2011 |
Saia RS, Bertozi G, Cunha FQ, Cárnio EC. Estradiol and thermoregulation in adult endotoxemic rats exposed to lipopolysaccharide in neonatal life. Acta Physiologica. 203: 429-439. PMID 21692993 DOI: 10.1111/J.1748-1716.2011.02334.X |
0.346 |
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| 2011 |
Niedbala W, Alves-Filho JC, Fukada SY, Vieira SM, Mitani A, Sonego F, Mirchandani A, Nascimento DC, Cunha FQ, Liew FY. Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proceedings of the National Academy of Sciences of the United States of America. 108: 9220-5. PMID 21576463 DOI: 10.1073/Pnas.1100667108 |
0.408 |
|
| 2011 |
Rocha FA, Silva FS, Leite AC, Leite AK, Girão VC, Castro RR, Cunha FQ. Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release. British Journal of Pharmacology. 164: 828-35. PMID 21557731 DOI: 10.1111/J.1476-5381.2011.01469.X |
0.445 |
|
| 2011 |
Freitas A, Alves-Filho JC, Trevelin SC, Spiller F, Suavinha MM, Nascimento DC, Pestana CR, Dal-Secco D, Sônego F, Czaikoski PG, Curti C, Barja-Fidalgo C, Cunha FQ. Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis. Shock (Augusta, Ga.). 35: 550-9. PMID 21330952 DOI: 10.1097/Shk.0B013E31820E1Ef0 |
0.421 |
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| 2011 |
Souto FO, Zarpelon AC, Staurengo-Ferrari L, Fattori V, Casagrande R, Fonseca MJ, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Quercetin reduces neutrophil recruitment induced by CXCL8, LTB4, and fMLP: inhibition of actin polymerization. Journal of Natural Products. 74: 113-8. PMID 21275387 DOI: 10.1021/Np1003017 |
0.783 |
|
| 2011 |
Carvalho TT, Flauzino T, Otaguiri ES, Batistela AP, Zarpelon AC, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Granulocyte-colony stimulating factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice. Pharmacology, Biochemistry, and Behavior. 98: 188-95. PMID 21236293 DOI: 10.1016/J.Pbb.2010.12.027 |
0.762 |
|
| 2011 |
Donate PB, Fornari TA, Junta CM, Magalhães DA, Macedo C, Cunha TM, Nguyen C, Cunha FQ, Passos GA. Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus. Immunobiology. 216: 591-603. PMID 21168240 DOI: 10.1016/J.Imbio.2010.09.007 |
0.504 |
|
| 2011 |
Spiller F, Costa C, Souto FO, Vinchi F, Mestriner FL, Laure HJ, Alves-Filho JC, Freitas A, Rosa JC, Ferreira SH, Altruda F, Hirsch E, Greene LJ, Tolosano E, Cunha FQ. Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice. American Journal of Respiratory and Critical Care Medicine. 183: 922-31. PMID 20971829 DOI: 10.1164/Rccm.201002-0223Oc |
0.644 |
|
| 2011 |
Paula-Neto HA, Alves-Filho JC, Souto FO, Spiller F, Amêndola RS, Freitas A, Cunha FQ, Barja-Fidalgo C. Inhibition of guanylyl cyclase restores neutrophil migration and maintains bactericidal activity increasing survival in sepsis. Shock (Augusta, Ga.). 35: 17-27. PMID 20823697 DOI: 10.1097/Shk.0B013E3181E37Ea8 |
0.396 |
|
| 2011 |
Paula JS, Oliveira MB, Chahud F, Modulo CM, Rocha EM, Cunha FQ. Efeito do dinitrato de isossorbida sobre a hiperalgesia corneana induzida por lipopolissacarídeo Revista Brasileira De Oftalmologia. 70: 290-295. DOI: 10.1590/S0034-72802011000500004 |
0.33 |
|
| 2010 |
Queiroz-Junior CM, Silva MJB, Corrêa JD, Madeira MFM, Garlet TP, Garlet GP, Cunha FQ, Teixeira MM, Silva TAd. A Controversial Role for IL-12 in Immune Response and Bone Resorption at Apical Periodontal Sites Clinical & Developmental Immunology. 2010: 327417-327417. PMID 21350602 DOI: 10.1155/2010/327417 |
0.394 |
|
| 2010 |
Soares PM, Lima-Junior RC, Mota JM, Justino PF, Brito GA, Ribeiro RA, Cunha FQ, Souza MH. Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice. Cancer Chemotherapy and Pharmacology. 68: 713-20. PMID 21153821 DOI: 10.1007/S00280-010-1540-5 |
0.368 |
|
| 2010 |
Cunha TM, Talbot J, Pinto LG, Vieira SM, Souza GR, Guerrero AT, Sonego F, Verri WA, Zamboni DS, Ferreira SH, Cunha FQ. Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation. Molecular Pain. 6: 63. PMID 20920345 DOI: 10.1186/1744-8069-6-63 |
0.797 |
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| 2010 |
Conte F, Menezes‐de‐Lima O, Verri W, Cunha F, Penido C, Henriques M. Lipoxin A4 attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects British Journal of Pharmacology. 161: 911-924. PMID 20860668 DOI: 10.1111/J.1476-5381.2010.00950.X |
0.445 |
|
| 2010 |
Lima FO, Souza GR, Verri WA, Parada CA, Ferreira SH, Cunha FQ, Cunha TM. Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain. 151: 506-515. PMID 20813459 DOI: 10.1016/J.Pain.2010.08.014 |
0.785 |
|
| 2010 |
Souto FO, Alves-Filho JC, Turato WM, Auxiliadora-Martins M, Basile-Filho A, Cunha FQ. Essential role of CCR2 in neutrophil tissue infiltration and multiple organ dysfunction in sepsis. American Journal of Respiratory and Critical Care Medicine. 183: 234-42. PMID 20732989 DOI: 10.1164/Rccm.201003-0416Oc |
0.335 |
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| 2010 |
Alves-Filho JC, Spiller F, Cunha FQ. Neutrophil paralysis in sepsis. Shock (Augusta, Ga.). 15-21. PMID 20714263 DOI: 10.1097/Shk.0B013E3181E7E61B |
0.323 |
|
| 2010 |
Figueiredo JG, Bitencourt FS, Cunha TM, Luz PB, Nascimento KS, Mota MRL, Sampaio AH, Cavada BS, Cunha FQ, Alencar NMN. Agglutinin isolated from the red marine alga Hypnea cervicornis J. Agardh reduces inflammatory hypernociception: Involvement of nitric oxide Pharmacology, Biochemistry and Behavior. 96: 371-377. PMID 20600247 DOI: 10.1016/J.Pbb.2010.06.008 |
0.64 |
|
| 2010 |
Nascimento DC, Alves-Filho JC, Sônego F, Fukada SY, Pereira MS, Benjamim C, Zamboni DS, Silva JS, Cunha FQ. Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis Critical Care Medicine. 38: 1718-1725. PMID 20543670 DOI: 10.1097/CCM.0b013e3181e78ad0 |
0.456 |
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| 2010 |
Gomes DA, Giusti-Paiva A, Ventura RR, Elias LL, Cunha FQ, Antunes-Rodrigues J. Carbon monoxide and nitric oxide modulate hyperosmolality-induced oxytocin secretion by the hypothalamus in vitro. Bioscience Reports. 30: 351-7. PMID 20518746 DOI: 10.1042/Bsr2009010 |
0.329 |
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| 2010 |
Martin EL, Souza DG, Fagundes CT, Amaral FA, Assenzio B, Puntorieri V, Del Sorbo L, Fanelli V, Bosco M, Delsedime L, Pinho JF, Lemos VS, Souto FO, Alves-Filho JC, Cunha FQ, et al. Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment. American Journal of Respiratory and Critical Care Medicine. 182: 762-73. PMID 20508212 DOI: 10.1164/Rccm.201001-0088Oc |
0.369 |
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| 2010 |
Alves-Filho JC, Sônego F, Souto FO, Freitas A, Verri WA, Auxiliadora-Martins M, Basile-Filho A, McKenzie AN, Xu D, Cunha FQ, Liew FY. Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nature Medicine. 16: 708-12. PMID 20473304 DOI: 10.1038/Nm.2156 |
0.649 |
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| 2010 |
Verri WA, Souto FO, Vieira SM, Almeida SC, Fukada SY, Xu D, Alves-Filho JC, Cunha TM, Guerrero AT, Mattos-Guimaraes RB, Oliveira FR, Teixeira MM, Silva JS, McInnes IB, Ferreira SH, ... ... Cunha FQ, et al. IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases. 69: 1697-703. PMID 20472598 DOI: 10.1136/Ard.2009.122655 |
0.805 |
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| 2010 |
Pavanelli WR, Gutierrez FR, Mariano FS, Prado CM, Ferreira BR, Teixeira MM, Canetti C, Rossi MA, Cunha FQ, Silva JS. 5-lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection. Microbes and Infection / Institut Pasteur. 12: 587-97. PMID 20381637 DOI: 10.1016/J.Micinf.2010.03.016 |
0.723 |
|
| 2010 |
Dal-Secco D, Freitas A, Abreu MA, Garlet TP, Rossi MA, Ferreira SH, Silva JS, Alves-Filho JC, Cunha FQ. Reduction of ICAM-1 expression by carbon monoxide via soluble guanylate cyclase activation accounts for modulation of neutrophil migration. Naunyn-Schmiedeberg's Archives of Pharmacology. 381: 483-93. PMID 20349048 DOI: 10.1007/S00210-010-0500-2 |
0.733 |
|
| 2010 |
Spiller F, Orrico MI, Nascimento DC, Czaikoski PG, Souto FO, Alves-Filho JC, Freitas A, Carlos D, Montenegro MF, Neto AF, Ferreira SH, Rossi MA, Hothersall JS, Assreuy J, Cunha FQ. Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation. American Journal of Respiratory and Critical Care Medicine. 182: 360-8. PMID 20339148 DOI: 10.1164/rccm.200907-1145OC |
0.579 |
|
| 2010 |
Godoi DF, Cardoso CR, Ferraz DB, Provinciatto PR, Cunha FQ, Silva JS, Voltarelli JC. Hematopoietic SCT modulates gut inflammation in experimental inflammatory bowel disease. Bone Marrow Transplantation. 45: 1562-71. PMID 20228850 DOI: 10.1038/Bmt.2010.6 |
0.553 |
|
| 2010 |
Queto T, Gaspar-Elsas MI, Masid-de-Brito D, Vasconcelos ZF, Ferraris FK, Penido C, Cunha FQ, Kanaoka Y, Lam BK, Xavier-Elsas P. Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow. Journal of Leukocyte Biology. 87: 885-93. PMID 20219953 DOI: 10.1189/Jlb.1108709 |
0.407 |
|
| 2010 |
Claudino M, Garlet TP, Cardoso CR, de Assis GF, Taga R, Cunha FQ, Silva JS, Garlet GP. Down-regulation of expression of osteoblast and osteocyte markers in periodontal tissues associated with the spontaneous alveolar bone loss of interleukin-10 knockout mice. European Journal of Oral Sciences. 118: 19-28. PMID 20156261 DOI: 10.1111/J.1600-0722.2009.00706.X |
0.566 |
|
| 2010 |
Cunha TM, Roman-Campos D, Lotufo CM, Duarte HL, Souza GR, Verri WA, Funez MI, Dias QM, Schivo IR, Domingues AC, Sachs D, Chiavegatto S, Teixeira MM, Hothersall JS, Cruz JS, ... Cunha FQ, et al. Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 4442-7. PMID 20147620 DOI: 10.1073/Pnas.0914733107 |
0.794 |
|
| 2010 |
Celes MR, Torres-Dueñas D, Malvestio LM, Blefari V, Campos EC, Ramos SG, Prado CM, Cunha FQ, Rossi MA. Disruption of sarcolemmal dystrophin and beta-dystroglycan may be a potential mechanism for myocardial dysfunction in severe sepsis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 531-42. PMID 20142806 DOI: 10.1038/Labinvest.2010.3 |
0.304 |
|
| 2010 |
Pinto LG, Cunha TM, Vieira SM, Lemos HP, Verri WA, Cunha FQ, Ferreira SH. IL-17 mediates articular hypernociception in antigen-induced arthritis in mice. Pain. 148: 247-56. PMID 19969421 DOI: 10.1016/J.Pain.2009.11.006 |
0.799 |
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| 2010 |
Gomes AS, Lima SJ, Gadelha GG, Barbosa ALR, Medeiros JVR, Cunha FQ, Soares PMG, Souza MH. W1722 Role of Soluble Guanylate Cyclase (sGC) and Constitutive NO Synthase (cNOS) in the Gastroprotection of Hemeoxigenase-1 (HO-1)/Biliverdin/Co Pathway Against Indomethacin- Induced Gastric Damage in Mice Gastroenterology. 138: S-726-S-727. DOI: 10.1016/S0016-5085(10)63342-2 |
0.334 |
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| 2009 |
Valério DA, Georgetti SR, Magro DA, Casagrande R, Cunha TM, Vicentini FT, Vieira SM, Fonseca MJ, Ferreira SH, Cunha FQ, Verri WA. Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. Journal of Natural Products. 72: 1975-9. PMID 19899776 DOI: 10.1021/Np900259Y |
0.811 |
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| 2009 |
Villarreal CF, Funez MI, Figueiredo F, Cunha FQ, Parada CA, Ferreira SH. Acute and persistent nociceptive paw sensitisation in mice: the involvement of distinct signalling pathways. Life Sciences. 85: 822-9. PMID 19896488 DOI: 10.1016/J.Lfs.2009.10.018 |
0.799 |
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| 2009 |
Alencar NM, Oliveira RS, Figueiredo JG, Cavalcante IJ, Matos MP, Cunha FQ, Nunes JV, Bomfim LR, Ramos MV. An anti-inflammatory lectin from Luetzelburgia auriculata seeds inhibits adhesion and rolling of leukocytes and modulates histamine and PGE2 action in acute inflammation models. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 59: 245-54. PMID 19757085 DOI: 10.1007/S00011-009-0092-9 |
0.375 |
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| 2009 |
Alves CF, Alves VB, de Assis IP, Clemente-Napimoga JT, Uber-Bucek E, Dal-Secco D, Cunha FQ, Rehder VL, Napimoga MH. Anti-inflammatory activity and possible mechanism of extract from Mikania laevigata in carrageenan-induced peritonitis. The Journal of Pharmacy and Pharmacology. 61: 1097-104. PMID 19703354 DOI: 10.1211/Jpp.61.08.0014 |
0.427 |
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| 2009 |
Vieira SM, Lemos HP, Grespan R, Napimoga MH, Dal-Secco D, Freitas A, Cunha TM, Verri WA, Souza-Junior DA, Jamur MC, Fernandes KS, Oliver C, Silva JS, Teixeira MM, Cunha FQ. A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5. British Journal of Pharmacology. 158: 779-89. PMID 19702783 DOI: 10.1111/J.1476-5381.2009.00367.X |
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| 2009 |
Souza DG, Fagundes CT, Sousa LP, Amaral FA, Souza RS, Souza AL, Kroon EG, Sachs D, Cunha FQ, Bukin E, Atrasheuskaya A, Ignatyev G, Teixeira MM. Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection. Proceedings of the National Academy of Sciences of the United States of America. 106: 14138-43. PMID 19666557 DOI: 10.1073/Pnas.0906467106 |
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| 2009 |
Ramos MV, Oliveira JS, Figueiredo JG, Figueiredo IS, Kumar VL, Bitencourt FS, Cunha FQ, Oliveira RS, Bomfim LR, Vitor Lima-Filho J, Alencar NM. Involvement of NO in the inhibitory effect of Calotropis procera latex protein fractions on leukocyte rolling, adhesion and infiltration in rat peritonitis model. Journal of Ethnopharmacology. 125: 387-92. PMID 19647058 DOI: 10.1016/J.Jep.2009.07.030 |
0.371 |
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| 2009 |
Pena-dos-Santos DR, Severino FP, Pereira SA, Rodrigues DB, Cunha FQ, Vieira SM, Napimoga MH, Clemente-Napimoga JT. Activation of peripheral kappa/delta opioid receptors mediates 15-deoxy-(Delta12,14)-prostaglandin J2 induced-antinociception in rat temporomandibular joint. Neuroscience. 163: 1211-9. PMID 19647045 DOI: 10.1016/J.Neuroscience.2009.07.052 |
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| 2009 |
Valério D, Ferreira F, Cunha T, Alves-Filho J, Lima F, Oliveira JD, Ferreira S, Cunha F, Queiroz R, Verri W. Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors British Journal of Pharmacology. 158: 558-568. PMID 19645715 DOI: 10.1111/J.1476-5381.2009.00325.X |
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| 2009 |
Hassumi MY, Silva-Filho VJ, Campos-Júnior JC, Vieira SM, Cunha FQ, Alves PM, Alves JB, Kawai T, Gonçalves RB, Napimoga MH. PPAR-gamma agonist rosiglitazone prevents inflammatory periodontal bone loss by inhibiting osteoclastogenesis. International Immunopharmacology. 9: 1150-8. PMID 19508902 DOI: 10.1016/J.Intimp.2009.06.002 |
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| 2009 |
Secher T, Vasseur V, Poisson DM, Mitchell JA, Cunha FQ, Alves-Filho JC, Ryffel B. Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7855-64. PMID 19494310 DOI: 10.4049/Jimmunol.0804008 |
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| 2009 |
Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sônego F, Cunha FQ, Ryffel B. IL-17 receptor signaling is required to control polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7846-54. PMID 19494309 DOI: 10.4049/Jimmunol.0803039 |
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| 2009 |
Medeiros JV, Bezerra VH, Gomes AS, Barbosa AL, Lima-Júnior RC, Soares PM, Brito GA, Ribeiro RA, Cunha FQ, Souza MH. Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons. The Journal of Pharmacology and Experimental Therapeutics. 330: 764-70. PMID 19491326 DOI: 10.1124/Jpet.109.152801 |
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| 2009 |
Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proceedings of the National Academy of Sciences of the United States of America. 106: 5954-9. PMID 19289819 DOI: 10.1073/Pnas.0812782106 |
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| 2009 |
Alves-Filho JC, Freitas A, Souto FO, Spiller F, Paula-Neto H, Silva JS, Gazzinelli RT, Teixeira MM, Ferreira SH, Cunha FQ. Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4018-23. PMID 19234125 DOI: 10.1073/Pnas.0900196106 |
0.725 |
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| 2009 |
Sachs D, Villarreal C, Cunha F, Parada C, Ferreira S. The role of PKA and PKCε pathways in prostaglandin E2-mediated hypernociception British Journal of Pharmacology. 156: 826-834. PMID 19220288 DOI: 10.1111/J.1476-5381.2008.00093.X |
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| 2009 |
Leite AC, Cunha FQ, Dal-Secco D, Fukada SY, Girão VC, Rocha FA. Effects of nitric oxide on neutrophil influx depends on the tissue: role of leukotriene B4 and adhesion molecules. British Journal of Pharmacology. 156: 818-25. PMID 19220287 DOI: 10.1111/J.1476-5381.2008.00094.X |
0.422 |
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| 2009 |
Nunes BS, Rensonnet NS, Dal-Secco D, Vieira SM, Cavada BS, Teixeira EH, Moura TR, Teixeira CS, Clemente-Napimoga JT, Cunha FQ, Napimoga MH. Lectin extracted from Canavalia grandiflora seeds presents potential anti-inflammatory and analgesic effects. Naunyn-Schmiedeberg's Archives of Pharmacology. 379: 609-16. PMID 19153712 DOI: 10.1007/S00210-009-0397-9 |
0.45 |
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| 2009 |
Cardoso CR, Provinciatto PR, Godoi DF, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. IL-4 regulates susceptibility to intestinal inflammation in murine food allergy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G593-600. PMID 19136382 DOI: 10.1152/Ajpgi.90431.2008 |
0.566 |
|
| 2009 |
Fukada SY, Silva TA, Garlet GP, Rosa AL, Da Silva JS, Cunha FQ. Factors involved in the T helper type 1 and type 2 cell commitment and osteoclast regulation in inflammatory apical diseases Oral Microbiology and Immunology. 24: 25-31. PMID 19121066 DOI: 10.1111/J.1399-302X.2008.00469.X |
0.348 |
|
| 2009 |
Napimoga MH, Benatti BB, Lima FO, Alves PM, Campos AC, Pena-Dos-Santos DR, Severino FP, Cunha FQ, Guimarães FS. Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats. International Immunopharmacology. 9: 216-22. PMID 19070683 DOI: 10.1016/J.Intimp.2008.11.010 |
0.377 |
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| 2009 |
Fukada SY, Silva TA, Saconato IF, Garlet GP, Avila-Campos MJ, Silva JS, Cunha FQ. iNOS-derived nitric oxide modulates infection-stimulated bone loss. Journal of Dental Research. 87: 1155-9. PMID 19029085 DOI: 10.1177/154405910808701207 |
0.547 |
|
| 2009 |
Verri WA, Cunha TM, Magro DA, Guerrero AT, Vieira SM, Carregaro V, Souza GR, Henriques Md, Ferreira SH, Cunha FQ. Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 379: 271-9. PMID 18854982 DOI: 10.1007/S00210-008-0360-1 |
0.788 |
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| 2009 |
Alves-Filho J, Sonego F, Souto F, Freitas A, Verri W, Xu D, Cunha F, Liew F. IL-33 protects mice from sepsis by inhibiting TLR4 signaling Critical Care. 13: 43. DOI: 10.1186/Cc8099 |
0.437 |
|
| 2009 |
Czaikoski P, Nascimento D, Spiller F, Cunha F. Heme oxygenase and soluble guanylate cyclase mediate the neutrophil migration failure to the lung in severe sepsis induced by pneumonia Critical Care. 13: 24. DOI: 10.1186/Cc7826 |
0.306 |
|
| 2009 |
Sônego F, Alves-Filho J, Freitas A, Nascimento D, Zamboni D, Cunha F. Caspase-1-deficient mice are more resistant to severe sepsis Critical Care. 13: 23. DOI: 10.1186/Cc7825 |
0.45 |
|
| 2009 |
Spiller F, Mestriner F, Laure H, Souto F, Alves-Filho J, Costa C, Freitas A, Rosa J, Ferreira S, Altruda F, Hirsch E, Tolosano E, Cunha F. Inhibitory role of the acute phase proteins on neutrophil migration in severe sepsis Critical Care. 13: 10. DOI: 10.1186/Cc7812 |
0.408 |
|
| 2009 |
Souto F, Alves-Filho J, Freitas A, Spiller F, Martins M, Basile-Filho A, Cunha F. CCR2 expression on neutrophils leads to detrimental tissue infiltration during sepsis Critical Care. 13: 9. DOI: 10.1186/Cc7811 |
0.428 |
|
| 2009 |
Casagrande R, Valerio D, Georgetti S, Magro D, Cunha T, Viventini F, Vieira S, Fonseca M, Ferreira S, Cunha F, Verri W. 234 Quercetin Reduces Inflammatory Pain: Inhibition Of Oxidative Stress And Cytokine Production European Journal of Pain. 13. DOI: 10.1016/S1090-3801(09)60237-8 |
0.373 |
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| 2009 |
Verri W, Cunha T, Vieira S, Souza G, Guerrero A, Sonego F, Zamboni D, Ferreira S, Cunha F. 112 CASPASE-1 IS CRITICAL FOR THE GENESIS OF INFLAMMATORY HYPERNOCICEPTION European Journal of Pain. 13: S41b-S42. DOI: 10.1016/S1090-3801(09)60115-4 |
0.355 |
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| 2008 |
Funez MI, Ferrari LF, Duarte DB, Sachs D, Cunha FQ, Lorenzetti BB, Parada CA, Ferreira SH. Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron. Proceedings of the National Academy of Sciences of the United States of America. 105: 19038-43. PMID 18799742 DOI: 10.1073/Pnas.0807922105 |
0.775 |
|
| 2008 |
Dal-Secco D, Cunha TM, Freitas A, Alves-Filho JC, Souto FO, Fukada SY, Grespan R, Alencar NM, Neto AF, Rossi MA, Ferreira SH, Hothersall JS, Cunha FQ. Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels. Journal of Immunology (Baltimore, Md. : 1950). 181: 4287-98. PMID 18768887 DOI: 10.4049/jimmunol.181.6.4287 |
0.729 |
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| 2008 |
Alves-Filho JC, de Freitas A, Spiller F, Souto FO, Cunha FQ. The role of neutrophils in severe sepsis. Shock (Augusta, Ga.). 30: 3-9. PMID 18704017 DOI: 10.1097/Shk.0B013E3181818466 |
0.384 |
|
| 2008 |
Cheraim AB, Xavier-Elsas P, de Oliveira SH, Batistella T, Russo M, Gaspar-Elsas MI, Cunha FQ. Leukotriene B4 is essential for selective eosinophil recruitment following allergen challenge of CD4+ cells in a model of chronic eosinophilic inflammation. Life Sciences. 83: 214-22. PMID 18601933 DOI: 10.1016/J.Lfs.2008.06.004 |
0.383 |
|
| 2008 |
Cunha TM, Dal-Secco D, Verri WA, Guerrero AT, Souza GR, Vieira SM, Lotufo CM, Neto AF, Ferreira SH, Cunha FQ. Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. European Journal of Pharmacology. 590: 127-35. PMID 18585702 DOI: 10.1016/J.Ejphar.2008.05.048 |
0.793 |
|
| 2008 |
Grespan R, Fukada SY, Lemos HP, Vieira SM, Napimoga MH, Teixeira MM, Fraser AR, Liew FY, McInnes IB, Cunha FQ. CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis and Rheumatism. 58: 2030-40. PMID 18576322 DOI: 10.1002/Art.23597 |
0.411 |
|
| 2008 |
Crema E, Silva BF, Silva PLe, Júnior VR, Cunha F. Innovative technique for the study of pneumoperitoneum in the evaluation of abdominal pain after chemical irritation with zymozan. Acta Cirurgica Brasileira. 23: 258-261. PMID 18552997 DOI: 10.1590/S0102-86502008000300008 |
0.301 |
|
| 2008 |
Mariano FS, Gutierrez FR, Pavanelli WR, Milanezi CM, Cavassani KA, Moreira AP, Ferreira BR, Cunha FQ, Cardoso CR, Silva JS. The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection. Microbes and Infection / Institut Pasteur. 10: 825-33. PMID 18538611 DOI: 10.1016/J.Micinf.2008.04.009 |
0.67 |
|
| 2008 |
Conte Fde P, Barja-Fidalgo C, Verri WA, Cunha FQ, Rae GA, Penido C, Henriques Md. Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1. Journal of Leukocyte Biology. 84: 652-60. PMID 18515326 DOI: 10.1189/Jlb.1207827 |
0.574 |
|
| 2008 |
Verri WA, Cunha TM, Magro DA, Domingues AC, Vieira SM, Souza GR, Liew FY, Ferreira SH, Cunha FQ. Role of IL-18 in overt pain-like behaviour in mice. European Journal of Pharmacology. 588: 207-12. PMID 18511039 DOI: 10.1016/J.Ejphar.2008.04.010 |
0.803 |
|
| 2008 |
Gutierrez FR, Lalu MM, Mariano FS, Milanezi CM, Cena J, Gerlach RF, Santos JE, Torres-Dueñas D, Cunha FQ, Schulz R, Silva JS. Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection. The Journal of Infectious Diseases. 197: 1468-76. PMID 18444803 DOI: 10.1086/587487 |
0.674 |
|
| 2008 |
Rocha FA, Leite AK, Pompeu MM, Cunha TM, Verri WA, Soares FM, Castro RR, Cunha FQ. Protective effect of an extract from Ascaris suum in experimental arthritis models. Infection and Immunity. 76: 2736-45. PMID 18411290 DOI: 10.1128/Iai.01085-07 |
0.694 |
|
| 2008 |
Garlet GP, Cardoso CR, Campanelli AP, Garlet TP, Avila-Campos MJ, Cunha FQ, Silva JS. The essential role of IFN-gamma in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice. Microbes and Infection. 10: 489-96. PMID 18403243 DOI: 10.1016/J.Micinf.2008.01.010 |
0.56 |
|
| 2008 |
Carregaro V, Valenzuela JG, Cunha TM, Verri WA, Grespan R, Matsumura G, Ribeiro JM, Elnaiem DE, Silva JS, Cunha FQ. Phlebotomine salivas inhibit immune inflammation-induced neutrophil migration via an autocrine DC-derived PGE2/IL-10 sequential pathway. Journal of Leukocyte Biology. 84: 104-14. PMID 18390928 DOI: 10.1189/Jlb.1107797 |
0.783 |
|
| 2008 |
Spiller F, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR. Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation. The Journal of Pharmacy and Pharmacology. 60: 473-8. PMID 18380920 DOI: 10.1211/Jpp.60.4.0010 |
0.462 |
|
| 2008 |
Cunha TM, Verri WA, Valério DA, Guerrero AT, Nogueira LG, Vieira SM, Souza DG, Teixeira MM, Poole S, Ferreira SH, Cunha FQ. Role of cytokines in mediating mechanical hypernociception in a model of delayed-type hypersensitivity in mice. European Journal of Pain (London, England). 12: 1059-68. PMID 18372199 DOI: 10.1016/J.Ejpain.2008.02.003 |
0.804 |
|
| 2008 |
Cunha TM, Barsante MM, Guerrero AT, Verri WA, Ferreira SH, Coelho FM, Bertini R, Di Giacinto C, Allegretti M, Cunha FQ, Teixeira MM. Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice. British Journal of Pharmacology. 154: 460-70. PMID 18362895 DOI: 10.1038/Bjp.2008.94 |
0.449 |
|
| 2008 |
Amaral FA, Sachs D, Costa VV, Fagundes CT, Cisalpino D, Cunha TM, Ferreira SH, Cunha FQ, Silva TA, Nicoli JR, Vieira LQ, Souza DG, Teixeira MM. Commensal microbiota is fundamental for the development of inflammatory pain. Proceedings of the National Academy of Sciences of the United States of America. 105: 2193-7. PMID 18268332 DOI: 10.1073/Pnas.0711891105 |
0.487 |
|
| 2008 |
Cruz KK, Fonseca SG, Monteiro MC, Silva OS, Andrade VM, Cunha FQ, Romão PR. The influence of glutathione modulators on the course of Leishmania major infection in susceptible and resistant mice. Parasite Immunology. 30: 171-4. PMID 18251971 DOI: 10.1111/J.1365-3024.2007.01014.X |
0.329 |
|
| 2008 |
Verri WA, Guerrero AT, Fukada SY, Valerio DA, Cunha TM, Xu D, Ferreira SH, Liew FY, Cunha FQ. IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 2723-8. PMID 18250323 DOI: 10.1073/Pnas.0712116105 |
0.787 |
|
| 2008 |
Souza MH, Mota JM, Oliveira RB, Cunha FQ. Gastric damage induced by different doses of indomethacin in rats is variably affected by inhibiting iNOS or leukocyte infiltration. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 57: 28-33. PMID 18209962 DOI: 10.1007/S00011-007-7089-Z |
0.341 |
|
| 2008 |
Cunha TM, Verri WA, Schivo IR, Napimoga MH, Parada CA, Poole S, Teixeira MM, Ferreira SH, Cunha FQ. Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. Journal of Leukocyte Biology. 83: 824-32. PMID 18203872 DOI: 10.1189/Jlb.0907654 |
0.813 |
|
| 2008 |
Fernandes KS, Neto EH, Brito MM, Silva JS, Cunha FQ, Barja-Fidalgo C. Detrimental role of endogenous nitric oxide in host defence against Sporothrix schenckii. Immunology. 123: 469-79. PMID 18194265 DOI: 10.1111/J.1365-2567.2007.02712.X |
0.568 |
|
| 2008 |
Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. Journal of Immunology (Baltimore, Md. : 1950). 180: 609-17. PMID 18097063 |
0.634 |
|
| 2008 |
Cardoso CR, Teixeira G, Provinciatto PR, Godoi DF, Ferreira BR, Milanezi CM, Ferraz DB, Rossi MA, Cunha FQ, Silva JS. Modulation of mucosal immunity in a murine model of food-induced intestinal inflammation. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 38: 338-49. PMID 18005184 DOI: 10.1111/J.1365-2222.2007.02866.X |
0.483 |
|
| 2008 |
Guerrero AT, Verri WA, Cunha TM, Silva TA, Schivo IR, Dal-Secco D, Canetti C, Rocha FA, Parada CA, Cunha FQ, Ferreira SH. Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. Journal of Leukocyte Biology. 83: 122-30. PMID 17913976 DOI: 10.1189/Jlb.0207123 |
0.802 |
|
| 2008 |
Oliveira SH, Canetti C, Ribeiro RA, Cunha FQ. Neutrophil migration induced by IL-1beta depends upon LTB4 released by macrophages and upon TNF-alpha and IL-1beta released by mast cells. Inflammation. 31: 36-46. PMID 17874178 DOI: 10.1007/S10753-007-9047-X |
0.404 |
|
| 2008 |
Soares PMG, Mota JMS, Brito GAC, Cunha FQ, Ribeiro RA, Souza MH. S1297 Role of IL-4 and IL-1β On the Pathogenesis of 5-Fluorouracil (5-FU) Induced Intestinal Inflammation in Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)61019-7 |
0.408 |
|
| 2007 |
Ting E, Guerrero AT, Cunha TM, Verri WA, Taylor SM, Woodruff TM, Cunha FQ, Ferreira SH. Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain. British Journal of Pharmacology. 153: 1043-53. PMID 18084313 DOI: 10.1038/Sj.Bjp.0707640 |
0.336 |
|
| 2007 |
Mestriner FL, Spiller F, Laure HJ, Souto FO, Tavares-Murta BM, Rosa JC, Basile-Filho A, Ferreira SH, Greene LJ, Cunha FQ. Acute-phase protein alpha-1-acid glycoprotein mediates neutrophil migration failure in sepsis by a nitric oxide-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 104: 19595-600. PMID 18048324 DOI: 10.1073/Pnas.0709681104 |
0.401 |
|
| 2007 |
Verri WA, Cunha TM, Ferreira SH, Wei X, Leung BP, Fraser A, McInnes IB, Liew FY, Cunha FQ. IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology. 37: 3373-80. PMID 17979156 DOI: 10.1002/Eji.200737488 |
0.791 |
|
| 2007 |
Napimoga MH, Souza GR, Cunha TM, Ferrari LF, Clemente-Napimoga JT, Parada CA, Verri WA, Cunha FQ, Ferreira SH. 15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor. The Journal of Pharmacology and Experimental Therapeutics. 324: 313-21. PMID 17928570 DOI: 10.1124/Jpet.107.126045 |
0.81 |
|
| 2007 |
Barsante MM, Cunha TM, Allegretti M, Cattani F, Policani F, Bizzarri C, Tafuri WL, Poole S, Cunha FQ, Bertini R, Teixeira MM. Blockade of the chemokine receptor CXCR2 ameliorates adjuvant-induced arthritis in rats. British Journal of Pharmacology. 153: 992-1002. PMID 17891165 DOI: 10.1038/Sj.Bjp.0707462 |
0.4 |
|
| 2007 |
Celes MR, Torres-Dueñas D, Alves-Filho JC, Duarte DB, Cunha FQ, Rossi MA. Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis. Critical Care Medicine. 35: 2176-85. PMID 17855834 DOI: 10.1097/01.Ccm.0000281454.97901.01 |
0.787 |
|
| 2007 |
Botelho MA, Rao VS, Carvalho CBM, Bezerra-Filho JG, Fonseca SGC, Vale ML, Montenegro D, Cunha F, Ribeiro RA, Brito GA. Lippia sidoides and Myracrodruon urundeuva gel prevents alveolar bone resorption in experimental periodontitis in rats. Journal of Ethnopharmacology. 113: 471-478. PMID 17714897 DOI: 10.1016/J.Jep.2007.07.010 |
0.37 |
|
| 2007 |
Cunha TM, Verri WA, Fukada SY, Guerrero AT, Santodomingo-Garzón T, Poole S, Parada CA, Ferreira SH, Cunha FQ. TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor. European Journal of Pharmacology. 573: 221-9. PMID 17669394 DOI: 10.1016/J.Ejphar.2007.07.007 |
0.801 |
|
| 2007 |
Melo ML, Brito GA, Soares RC, Carvalho SB, Silva JV, Soares PM, Vale ML, Souza MH, Cunha FQ, Ribeiro RA. Role of cytokines (TNF-alpha, IL-1beta and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide. Cancer Chemotherapy and Pharmacology. 61: 775-84. PMID 17624531 DOI: 10.1007/S00280-007-0534-4 |
0.421 |
|
| 2007 |
Napimoga MH, Cavada BS, Alencar NM, Mota ML, Bittencourt FS, Alves-Filho JC, Grespan R, Gonçalves RB, Clemente-Napimoga JT, de Freitas A, Parada CA, Ferreira SH, Cunha FQ. Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production. International Immunopharmacology. 7: 824-35. PMID 17466916 DOI: 10.1016/J.Intimp.2007.02.001 |
0.714 |
|
| 2007 |
Silva TA, Garlet GP, Fukada SY, Silva JS, Cunha FQ. Chemokines in oral inflammatory diseases: apical periodontitis and periodontal disease. Journal of Dental Research. 86: 306-19. PMID 17384024 DOI: 10.1177/154405910708600403 |
0.55 |
|
| 2007 |
Valério DA, Cunha TM, Arakawa NS, Lemos HP, Da Costa FB, Parada CA, Ferreira SH, Cunha FQ, Verri WA. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. European Journal of Pharmacology. 562: 155-63. PMID 17320857 DOI: 10.1016/J.Ejphar.2007.01.029 |
0.815 |
|
| 2007 |
Souza PP, Fukada SY, Cunha FQ, Costa CA, Costa-Neto CM. Regulation of angiotensin II receptors levels during rat induced pulpitis. Regulatory Peptides. 140: 27-31. PMID 17197045 DOI: 10.1016/J.Regpep.2006.11.008 |
0.354 |
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| 2007 |
Verri WA, Cunha TM, Parada CA, Poole S, Liew FY, Ferreira SH, Cunha FQ. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Behavior and Immunity. 21: 535-543. PMID 17194566 DOI: 10.1016/J.Bbi.2006.11.005 |
0.8 |
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| 2007 |
Pompermayer K, Amaral FA, Fagundes CT, Vieira AT, Cunha FQ, Teixeira MM, Souza DG. Effects of the treatment with glibenclamide, an ATP-sensitive potassium channel blocker, on intestinal ischemia and reperfusion injury. European Journal of Pharmacology. 556: 215-22. PMID 17182029 DOI: 10.1016/J.Ejphar.2006.10.065 |
0.349 |
|
| 2007 |
Garlet GP, Cardoso CR, Campanelli AP, Ferreira BR, Avila-Campos MJ, Cunha FQ, Silva JS. The dual role of p55 tumour necrosis factor-alpha receptor in Actinobacillus actinomycetemcomitans-induced experimental periodontitis: host protection and tissue destruction. Clinical and Experimental Immunology. 147: 128-38. PMID 17177972 DOI: 10.1111/J.1365-2249.2006.03260.X |
0.577 |
|
| 2007 |
Batista CK, Brito GA, Souza ML, Leitão BT, Cunha FQ, Ribeiro RA. A model of hemorrhagic cystitis induced with acrolein in mice. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 39: 1475-81. PMID 17146560 DOI: 10.1590/S0100-879X2006001100011 |
0.349 |
|
| 2007 |
Leitão RFC, Ribeiro RA, Bellaguarda EAL, Macedo FDB, Silva LR, Oriá RB, Vale ML, Cunha FQ, Brito GAC. Role of nitric oxide on pathogenesis of 5-fluorouracil induced experimental oral mucositis in hamster Cancer Chemotherapy and Pharmacology. 59: 603-612. PMID 16944152 DOI: 10.1007/S00280-006-0301-Y |
0.309 |
|
| 2007 |
Brito GA, Sachs D, Cunha FQ, Vale ML, Lotufo CM, Ferreira SH, Ribeiro RA. Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway. The European Journal of Neuroscience. 24: 1175-81. PMID 16930443 DOI: 10.1111/J.1460-9568.2006.04991.X |
0.801 |
|
| 2007 |
Silva TA, Ribeiro FLL, Oliveira-Neto HHD, Watanabe S, Alencar RDCG, Fukada SY, Cunha FQ, Leles CR, Mendonça EF, Batista AC. Dual role of CCL3/CCR1 in oral squamous cell carcinoma: implications in tumor metastasis and local host defense. Oncology Reports. 18: 1107-1113. DOI: 10.3892/Or.18.5.1107 |
0.308 |
|
| 2007 |
Verri WA, Cunha TM, Poole S, Ferreira SH, Cunha FQ. Cytokine inhibitors and pain control Revista Brasileira De Reumatologia. 47: 341-353. DOI: 10.1590/S0482-50042007000500009 |
0.324 |
|
| 2007 |
Mota JS, Soares PM, Brito GA, Cunha FQ, Souza ML, Ribeiro RA. Role of IL-1{beta} and IL-4 in 5-fluorouracil- induced intestinal mucositis in mice Journal of Clinical Oncology. 25: 19551-19551. DOI: 10.1200/Jco.2007.25.18_Suppl.19551 |
0.426 |
|
| 2007 |
Alves-Filho J, Freitas A, Spiller F, Souto F, Paula-Neto H, Silva J, Cunha F. TLR2 signaling downregulates chemokine receptor CXCR2 and impairs neutrophil migration in severe polymicrobial sepsis Critical Care. 11: P47. DOI: 10.1186/Cc6026 |
0.512 |
|
| 2007 |
Freitas A, Alves-Filho J, Suavinha M, Spiller F, Dal-Secco D, Cunha F. The critical role of heme oxygenase in neutrophil migration impairment in polymicrobial sepsis Critical Care. 11: P46. DOI: 10.1186/Cc6025 |
0.391 |
|
| 2007 |
Alves-Filho J, Freitas A, Spiller F, Souto F, Paula-Neto H, Silva J, Cunha F. Toll-like receptor 2 induces chemokine receptor CXCR2 downregulation and neutrophil migration impairment in severe sepsis Critical Care. 11: 3. DOI: 10.1186/Cc5790 |
0.514 |
|
| 2006 |
Alencar NM, Assreuy AM, Havt A, Benevides RG, de Moura TR, de Sousa RB, Ribeiro RA, Cunha FQ, Cavada BS. Vatairea macrocarpa (Leguminosae) lectin activates cultured macrophages to release chemotactic mediators. Naunyn-Schmiedeberg's Archives of Pharmacology. 374: 275-82. PMID 17171556 DOI: 10.1007/s00210-006-0124-8 |
0.354 |
|
| 2006 |
Scheicher ME, Teixeira MM, Cunha FQ, Teixeira AL, Filho JT, Vianna EO. Eotaxin-2 in sputum cell culture to evaluate asthma inflammation. The European Respiratory Journal. 29: 489-95. PMID 17079258 DOI: 10.1183/09031936.00060205 |
0.36 |
|
| 2006 |
de Souza RC, Cunha JM, Ferreira SH, Cunha FQ, Lima HC. Different inflammatory mediators induce inflammation and pain after application of liquid nitrogen to the skin. Cryobiology. 53: 319-29. PMID 17005173 DOI: 10.1016/J.Cryobiol.2006.08.003 |
0.68 |
|
| 2006 |
Freitas A, Alves-Filho JC, Secco DD, Neto AF, Ferreira SH, Barja-Fidalgo C, Cunha FQ. Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation. British Journal of Pharmacology. 149: 345-54. PMID 16953189 DOI: 10.1038/Sj.Bjp.0706882 |
0.348 |
|
| 2006 |
Gomes AS, Lima LM, Santos CL, Cunha FQ, Ribeiro RA, Souza MH. LPS from Escherichia coli protects against indomethacin-induced gastropathy in rats--role of ATP-sensitive potassium channels. European Journal of Pharmacology. 547: 136-42. PMID 16945368 DOI: 10.1016/J.Ejphar.2006.07.028 |
0.321 |
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| 2006 |
Santodomingo-Garzón T, Cunha TM, Verri WA, Valério DAR, Parada CA, Poole S, Ferreira SH, Cunha FQ. Atorvastatin inhibits inflammatory hypernociception British Journal of Pharmacology. 149: 14-22. PMID 16865092 DOI: 10.1038/Sj.Bjp.0706836 |
0.48 |
|
| 2006 |
Escalante RD, de Oliveira EC, Cunha FQ, Vespúcio MV, Ribeiro-Silva A, Aprilli F, Garcia SB. Trypanosoma cruzi infection and/or administration of the nonsteroidal anti-inflammatory nimesulide increase the number of colonic crypts overexpressing metallothioneins in rat colon carcinogenesis. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 39: 895-9. PMID 16862280 DOI: 10.1590/S0100-879X2006000700007 |
0.319 |
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| 2006 |
Ramos CD, Fernandes KS, Canetti C, Teixeira MM, Silva JS, Cunha FQ. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4). European Journal of Immunology. 36: 2025-34. PMID 16856209 DOI: 10.1002/eji.200636057 |
0.507 |
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| 2006 |
Arraes SM, Freitas MS, da Silva SV, de Paula Neto HA, Alves-Filho JC, Auxiliadora Martins M, Basile-Filho A, Tavares-Murta BM, Barja-Fidalgo C, Cunha FQ. Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. Blood. 108: 2906-13. PMID 16849637 DOI: 10.1182/Blood-2006-05-024638 |
0.45 |
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| 2006 |
Moreno SE, Alves-Filho JC, Rios-Santos F, Silva JS, Ferreira SH, Cunha FQ, Teixeira MM. Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 177: 1264-71. PMID 16818786 DOI: 10.4049/Jimmunol.177.2.1264 |
0.732 |
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| 2006 |
Guerrero AT, Verri WA, Cunha TM, Silva TA, Rocha FA, Ferreira SH, Cunha FQ, Parada CA. Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacology, Biochemistry, and Behavior. 84: 244-51. PMID 16797062 DOI: 10.1016/J.Pbb.2006.05.008 |
0.787 |
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| 2006 |
Carvalho AP, Bezerra MM, Girão VC, Cunha FQ, Rocha FA. Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice. Clinical and Experimental Pharmacology & Physiology. 33: 601-6. PMID 16789926 DOI: 10.1111/J.1440-1681.2006.04413.X |
0.428 |
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| 2006 |
Alves-Filho JC, Tavares-Murta BM, Barja-Fidalgo C, Benjamim CF, Basile-Filho A, Arraes SM, Cunha FQ. Neutrophil function in severe sepsis. Endocrine‚ Metabolic & Immune Disorders-Drug Targets. 6: 151-158. PMID 16787289 DOI: 10.2174/187153006777442404 |
0.407 |
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| 2006 |
Verri WA, Cunha TM, Parada CA, Wei XQ, Ferreira SH, Liew FY, Cunha FQ. IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-gamma, endothelin, and prostaglandin. Proceedings of the National Academy of Sciences of the United States of America. 103: 9721-5. PMID 16766656 DOI: 10.1073/Pnas.0603286103 |
0.796 |
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| 2006 |
Verri WA, Cunha TM, Parada CA, Poole S, Cunha FQ, Ferreira SH. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacology & Therapeutics. 112: 116-38. PMID 16730375 DOI: 10.1016/J.Pharmthera.2006.04.001 |
0.81 |
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| 2006 |
Carvalho RF, Ribeiro RA, Falcão RA, Lima RC, Leitão RF, Alcantara C, Souza MH, Cunha FQ, Brito GA. Angiotensin II potentiates inflammatory edema in rats: Role of mast cell degranulation. European Journal of Pharmacology. 540: 175-82. PMID 16716292 DOI: 10.1016/J.Ejphar.2006.04.014 |
0.349 |
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| 2006 |
Soares AC, Souza DG, Pinho V, Vieira AT, Nicoli JR, Cunha FQ, Mantovani A, Reis LF, Dias AA, Teixeira MM. Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice. Microbes and Infection / Institut Pasteur. 8: 1321-9. PMID 16697676 DOI: 10.1016/J.Micinf.2005.12.017 |
0.383 |
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| 2006 |
Cavalcante IC, Castro MV, Barreto AR, Sullivan GW, Vale M, Almeida PR, Linden J, Rieger JM, Cunha FQ, Guerrant RL, Ribeiro RA, Brito GA. Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis. Infection and Immunity. 74: 2606-12. PMID 16622196 DOI: 10.1128/Iai.74.5.2606-2612.2006 |
0.417 |
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| 2006 |
Dal Secco D, Moreira AP, Freitas A, Silva JS, Rossi MA, Ferreira SH, Cunha FQ. Nitric oxide inhibits neutrophil migration by a mechanism dependent on ICAM-1: role of soluble guanylate cyclase. Nitric Oxide : Biology and Chemistry. 15: 77-86. PMID 16621629 DOI: 10.1016/J.NIOX.2006.02.004 |
0.716 |
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| 2006 |
Vale ML, Cunha FQ, Brito GA, Benevides VM, Ferreira SH, Poole S, Ribeiro RA. Anti-nociceptive effect of thalidomide on zymosan-induced experimental articular incapacitation. European Journal of Pharmacology. 536: 309-17. PMID 16597438 DOI: 10.1016/J.Ejphar.2006.02.051 |
0.667 |
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| 2006 |
Torres-Dueñas D, Benjamim CF, Ferreira SH, Cunha FQ. Failure of neutrophil migration to infectious focus and cardiovascular changes on sepsis in rats: Effects of the inhibition of nitric oxide production, removal of infectious focus, and antimicrobial treatment. Shock (Augusta, Ga.). 25: 267-76. PMID 16552359 DOI: 10.1097/01.Shk.0000208804.34292.38 |
0.403 |
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| 2006 |
Alves-Filho JC, de Freitas A, Russo M, Cunha FQ. Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis. Critical Care Medicine. 34: 461-70. PMID 16424729 DOI: 10.1097/01.Ccm.0000198527.71819.E1 |
0.392 |
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| 2006 |
Garlet GP, Cardoso CR, Silva TA, Ferreira BR, Avila-Campos MJ, Cunha FQ, Silva JS. Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors. Oral Microbiology and Immunology. 21: 12-20. PMID 16390336 DOI: 10.1111/J.1399-302X.2005.00245.X |
0.543 |
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| 2005 |
Carvalho M, Benjamim C, Santos F, Ferreira S, Cunha F. Effect of mast cells depletion on the failure of neutrophil migration during sepsis. European Journal of Pharmacology. 525: 161-9. PMID 16266701 DOI: 10.1016/J.Ejphar.2005.09.049 |
0.649 |
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| 2005 |
Nascimento SB, Sousa RB, Martins MJ, Souza Gomes A, Souza MH, Guerrant RL, Cunha FQ, Ribeiro RA, Brito GA. Glutamine depletion potentiates leucocyte-dependent inflammatory events induced by carrageenan or Clostridium difficile toxin A in rats. Immunology. 116: 328-36. PMID 16236122 DOI: 10.1111/J.1365-2567.2005.02232.X |
0.431 |
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| 2005 |
Silva TA, Garlet GP, Lara VS, Martins W, Silva JS, Cunha FQ. Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. Oral Microbiology and Immunology. 20: 310-6. PMID 16101967 DOI: 10.1111/J.1399-302X.2005.00232.X |
0.566 |
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| 2005 |
Villarreal CF, Sachs D, Cunha FQ, Parada CA, Ferreira SH. The role of Na(V)1.8 sodium channel in the maintenance of chronic inflammatory hypernociception. Neuroscience Letters. 386: 72-7. PMID 16043287 DOI: 10.1016/j.neulet.2005.04.060 |
0.779 |
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| 2005 |
Verri WA, Molina RO, Schivo IR, Cunha TM, Parada CA, Poole S, Ferreira SH, Cunha FQ. Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. The Journal of Pharmacology and Experimental Therapeutics. 315: 609-15. PMID 16024732 DOI: 10.1124/Jpet.105.089409 |
0.792 |
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| 2005 |
Monteiro MC, Nogueira LG, Almeida Souza AA, Ribeiro JM, Silva JS, Cunha FQ. Effect of salivary gland extract of Leishmania vector, Lutzomyia longipalpis, on leukocyte migration in OVA-induced immune peritonitis. European Journal of Immunology. 35: 2424-33. PMID 15997469 DOI: 10.1002/Eji.200526160 |
0.63 |
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| 2005 |
Alves-Filho JC, Benjamim C, Tavares-Murta BM, Cunha FQ. Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome. Memorias Do Instituto Oswaldo Cruz. 223-6. PMID 15962127 DOI: 10.1590/S0074-02762005000900038 |
0.445 |
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| 2005 |
Lima V, Brito GA, Cunha FQ, Rebouças CG, Falcão BA, Augusto RF, Souza ML, Leitão BT, Ribeiro RA. Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. European Journal of Oral Sciences. 113: 210-7. PMID 15953245 DOI: 10.1111/J.1600-0722.2005.00216.X |
0.363 |
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| 2005 |
Ramos CD, Canetti C, Souto JT, Silva JS, Hogaboam CM, Ferreira SH, Cunha FQ. MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4. Journal of Leukocyte Biology. 78: 167-77. PMID 15831559 DOI: 10.1189/Jlb.0404237 |
0.711 |
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| 2005 |
Paoliello-Paschoalato AB, Oliveira SHP, Cunha FQ. Interleukin 4 induces the expression of inducible nitric oxide synthase in eosinophils. Cytokine. 30: 116-124. PMID 15826818 DOI: 10.1016/J.Cyto.2005.01.001 |
0.433 |
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| 2005 |
Cunha TM, Verri WA, Silva JS, Poole S, Cunha FQ, Ferreira SH. A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 1755-60. PMID 15665080 DOI: 10.1073/Pnas.0409225102 |
0.607 |
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| 2005 |
Benjamim CF, Canetti C, Cunha FQ, Kunkel SL, Peters-Golden M. Opposing and hierarchical roles of leukotrienes in local innate immune versus vascular responses in a model of sepsis. Journal of Immunology (Baltimore, Md. : 1950). 174: 1616-20. PMID 15661924 DOI: 10.4049/Jimmunol.174.3.1616 |
0.365 |
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| 2004 |
Silva MdFSd, Nóbrega Ad, Barja-Fidalgo TC, Brando-Lima AC, Cunha F, Silva ACd. Genetic selection for susceptibility to oral tolerance leads to a profound reduction of the acute inflammatory response. Annals of the New York Academy of Sciences. 1029: 398-401. PMID 15681791 DOI: 10.1196/Annals.1309.024 |
0.304 |
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| 2004 |
Scognamillo‐Szabó MVR, Bechara GH, Ferreira SH, Cunha FQ. Effect of Various Acupuncture Treatment Protocols upon Sepsis in Wistar Rats Annals of the New York Academy of Sciences. 1026: 251-256. PMID 15604502 DOI: 10.1196/Annals.1307.039 |
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| 2004 |
Feldmeier H, Witt L, Schwalfenberg S, Ribeiro RA, Cunha FQ, Harms G, Mehlhorn H, Liesenfeld O, Heukelbach J. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. V. Cytokine concentrations in experimentally infected Wistar rats. Parasitology Research. 94: 371-376. PMID 15549386 DOI: 10.1007/S00436-004-1219-0 |
0.404 |
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| 2004 |
Vale ML, Benevides VM, Sachs D, Brito GA, da Rocha FA, Poole S, Ferreira SH, Cunha FQ, Ribeiro RA. Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. British Journal of Pharmacology. 143: 833-44. PMID 15520047 DOI: 10.1038/sj.bjp.0705999 |
0.784 |
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| 2004 |
Martins GA, Campanelli AP, Silva RB, Tadokoro CE, Russo M, Cunha FQ, Rizzo LV, Silva JS. CD28 is required for T cell activation and IFN-gamma production by CD4+ and CD8+ T cells in response to Trypanosoma cruzi infection. Microbes and Infection. 6: 1133-44. PMID 15488732 DOI: 10.1016/J.Micinf.2004.07.002 |
0.493 |
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| 2004 |
Silva TA, Lara VS, Silva JS, Garlet GP, Butler WT, Cunha FQ. Dentin sialoprotein and phosphoprotein induce neutrophil recruitment: a mechanism dependent on IL-1beta, TNF-beta, and CXC chemokines. Calcified Tissue International. 74: 532-41. PMID 15354861 DOI: 10.1007/S00223-003-0159-5 |
0.606 |
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| 2004 |
Silva TA, Lara VS, Rosa AL, Cunha FQ. Cytokine and chemokine response of bone cells after dentin challenge in vitro Oral Diseases. 10: 258-264. PMID 15315641 DOI: 10.1111/J.1601-0825.2004.01011.X |
0.398 |
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| 2004 |
Souza DG, Bertini R, Vieira AT, Cunha FQ, Poole S, Allegretti M, Colotta F, Teixeira MM. Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury. British Journal of Pharmacology. 143: 132-42. PMID 15302676 DOI: 10.1038/Sj.Bjp.0705862 |
0.343 |
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| 2004 |
Bombini G, Canetti C, Rocha FA, Cunha FQ. Tumour necrosis factor-alpha mediates neutrophil migration to the knee synovial cavity during immune inflammation. European Journal of Pharmacology. 496: 197-204. PMID 15288591 DOI: 10.1016/J.Ejphar.2004.06.003 |
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| 2004 |
Gomes DA, Reis WL, Ventura RR, Giusti-Paiva A, Elias LL, Cunha FQ, Antunes-Rodrigues J. The role of carbon monoxide and nitric oxide in hyperosmolality-induced atrial natriuretic peptide release by hypothalamus in vitro. Brain Research. 1016: 33-9. PMID 15234249 DOI: 10.1016/J.Brainres.2004.04.047 |
0.305 |
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| 2004 |
Souza MH, Lemos HP, Oliveira RB, Cunha FQ. Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide synthase (iNOS) deficient mice. Gut. 53: 791-6. PMID 15138204 DOI: 10.1136/Gut.2002.012930 |
0.392 |
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| 2004 |
Verri WA, Schivo IR, Cunha TM, Liew FY, Ferreira SH, Cunha FQ. Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. The Journal of Pharmacology and Experimental Therapeutics. 310: 710-7. PMID 15075358 DOI: 10.1124/Jpet.103.063990 |
0.795 |
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| 2004 |
Arantes RM, Marche HH, Bahia MT, Cunha FQ, Rossi MA, Silva JS. Interferon-gamma-induced nitric oxide causes intrinsic intestinal denervation in Trypanosoma cruzi-infected mice. The American Journal of Pathology. 164: 1361-8. PMID 15039223 DOI: 10.1016/S0002-9440(10)63222-1 |
0.491 |
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| 2004 |
Sachs D, Cunha FQ, Ferreira SH. Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 3680-5. PMID 14990791 DOI: 10.1073/Pnas.0308382101 |
0.786 |
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| 2004 |
Vieira MM, Brito GA, Belarmino-Filho JN, Macedo FY, Nery EA, Cunha FQ, Ribeiro RA. Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis. International Journal of Urology : Official Journal of the Japanese Urological Association. 10: 595-602. PMID 14633084 DOI: 10.1046/J.1442-2042.2003.00709.X |
0.302 |
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| 2004 |
Alencar NM, Assreuy AM, Alencar VB, Melo SC, Ramos MV, Cavada BS, Cunha FQ, Ribeiro RA. The galactose-binding lectin from Vatairea macrocarpa seeds induces in vivo neutrophil migration by indirect mechanism. The International Journal of Biochemistry & Cell Biology. 35: 1674-81. PMID 12962707 DOI: 10.1016/S1357-2725(03)00138-9 |
0.448 |
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| 2004 |
Cunha JM, Sachs D, Canetti CA, Poole S, Ferreira SH, Cunha FQ. The critical role of leukotriene B4 in antigen-induced mechanical hyperalgesia in immunised rats. British Journal of Pharmacology. 139: 1135-45. PMID 12871832 DOI: 10.1038/Sj.Bjp.0705346 |
0.815 |
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| 2004 |
Campebell R, Peiró J, Valadão C, Santana A, Cunha F. Effects of lidocaine on lipopolysaccharide-induced synovitis in horses Arquivo Brasileiro De Medicina VeterináRia E Zootecnia. 56: 281-291. DOI: 10.1590/S0102-09352004000300001 |
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| 2004 |
Santis GCD, Moreno SE, Teixera HLG, Lima ASG, Garcia AB, Falcao RP, Cunha FQ, Rego EM. Histone Deacetylase Inhibitors and Filgrastim Do Not Synergize with ATRA in the Induction of Changes of Acute Promyelocytic Leukemia Cells Adhesive Properties. Blood. 104: 2548-2548. DOI: 10.1182/Blood.V104.11.2548.2548 |
0.302 |
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| 2003 |
Fonseca SG, Romão PR, Figueiredo F, Morais RH, Lima HC, Ferreira SH, Cunha FQ. TNF-alpha mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis. European Journal of Immunology. 33: 2297-306. PMID 12884305 DOI: 10.1002/Eji.200320335 |
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| 2003 |
Canetti CA, Leung BP, Culshaw S, McInnes IB, Cunha FQ, Liew FY, Cannetti CA. IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B4. Journal of Immunology (Baltimore, Md. : 1950). 171: 1009-15. PMID 12847274 DOI: 10.4049/Jimmunol.171.2.1009 |
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| 2003 |
Rodríguez D, Keller AC, Faquim-Mauro EL, de Macedo MS, Cunha FQ, Lefort J, Vargaftig BB, Russo M. Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity. Journal of Immunology (Baltimore, Md. : 1950). 171: 1001-8. PMID 12847273 DOI: 10.4049/Jimmunol.171.2.1001 |
0.402 |
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| 2003 |
Ramos CDL, Heluy-Neto NE, Ribeiro RA, Ferreira SH, Cunha FQ. Neutrophil migration induced by IL-8-activated mast cells is mediated by CINC-1 Cytokine. 21: 214-223. PMID 12824006 DOI: 10.1016/S1043-4666(03)00050-4 |
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| 2003 |
Cunha FQ, Ferreira SH. Peripheral hyperalgesic cytokines. Advances in Experimental Medicine and Biology. 521: 22-39. PMID 12617562 |
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| 2003 |
Parada CA, Vivancos GG, Tambeli CH, Cunha FQ, Ferreira SH. Activation of presynaptic NMDA receptors coupled to NaV1.8-resistant sodium channel C-fibers causes retrograde mechanical nociceptor sensitization. Proceedings of the National Academy of Sciences of the United States of America. 100: 2923-8. PMID 12589028 DOI: 10.1073/pnas.252777799 |
0.579 |
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| 2003 |
Lorenzetti BB, Veiga FH, Canetti CA, Poole S, Cunha FQ, Ferreira SH. Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivitiy in rats. European Cytokine Network. 13: 456-61. PMID 12517731 |
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| 2003 |
Vale ML, Marques JB, Moreira CA, Rocha FA, Ferreira SH, Poole S, Cunha FQ, Ribeiro RA. Antinociceptive effects of interleukin-4, -10, and -13 on the writhing response in mice and zymosan-induced knee joint incapacitation in rats. The Journal of Pharmacology and Experimental Therapeutics. 304: 102-8. PMID 12490580 DOI: 10.1124/Jpet.102.038703 |
0.699 |
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| 2003 |
Assreuy AM, Calvete JJ, Alencar NM, Cavada BS, Rocha-Filho DR, Melo SC, Cunha FQ, Ribeiro RA. Spermadhesin PSP-I/PSP-II heterodimer and its isolated subunits induced neutrophil migration into the peritoneal cavity of rats. Biology of Reproduction. 67: 1796-803. PMID 12444055 DOI: 10.1095/Biolreprod.102.007013 |
0.354 |
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| 2002 |
Michelin MA, Figueiredo F, Cunha FQ. Involvement of prostaglandins in the immunosuppression occurring during experimental infection by Paracoccidioides brasiliensis. Experimental Parasitology. 102: 170-177. PMID 12856313 DOI: 10.1016/S0014-4894(03)00053-5 |
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| 2002 |
Assreuy AM, Alencar NM, Cavada BS, Rocha-Filho DR, Feitosa RF, Cunha FQ, Calvete JJ, Ribeiro RA. Porcine spermadhesin PSP-I/PSP-II stimulates macrophages to release a neutrophil chemotactic substance: modulation by mast cells. Biology of Reproduction. 68: 1836-41. PMID 12606406 DOI: 10.1095/Biolreprod.102.013425 |
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| 2002 |
Viana CFG, Melo DH, Carneiro-Filho BA, Michelin MA, Brito GAC, Cunha FQ, Lima AAM, Ribeiro RA. Pro-inflammatory effects of cholera toxin: role of tumor necrosis factor alpha. Toxicon. 40: 1487-1494. PMID 12368119 DOI: 10.1016/S0041-0101(02)00170-8 |
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Crosara-Alberto DP, Darini AL, Inoue RY, Silva JS, Ferreira SH, Cunha FQ. Involvement of NO in the failure of neutrophil migration in sepsis induced by Staphylococcus aureus. British Journal of Pharmacology. 136: 645-58. PMID 12086974 DOI: 10.1038/Sj.Bjp.0704734 |
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| 2002 |
Benjamim CF, Silva JS, Fortes ZB, Oliveira MA, Ferreira SH, Cunha FQ. Inhibition of leukocyte rolling by nitric oxide during sepsis leads to reduced migration of active microbicidal neutrophils. Infection and Immunity. 70: 3602-10. PMID 12065501 DOI: 10.1128/Iai.70.7.3602-3610.2002 |
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| 2002 |
Prado WA, Schiavon VF, Cunha FQ. Dual effect of local application of nitric oxide donors in a model of incision pain in rats. European Journal of Pharmacology. 441: 57-65. PMID 12007920 DOI: 10.1016/S0014-2999(02)01413-9 |
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| 2002 |
Tavares-Murta BM, Zaparoli M, Ferreira RB, Silva-Vergara ML, Oliveira CHB, Murta EFC, Ferreira SH, Cunha FQ. Failure of neutrophil chemotactic function in septic patients Critical Care Medicine. 30: 1056-1061. PMID 12006803 DOI: 10.1097/00003246-200205000-00017 |
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Oliveira SH, Costa CH, Ferreira SH, Cunha FQ. Sephadex induces eosinophil migration to the rat and mouse peritoneal cavity: involvement of mast cells, LTB4, TNF-alpha, IL-8 and PAF. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 51: 144-53. PMID 12005205 DOI: 10.1007/Pl00000286 |
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| 2002 |
Sachs D, Cunha FQ, Poole S, Ferreira SH. Tumour necrosis factor-alpha, interleukin-1beta and interleukin-8 induce persistent mechanical nociceptor hypersensitivity. Pain. 96: 89-97. PMID 11932065 DOI: 10.1016/S0304-3959(01)00433-X |
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| 2002 |
Canetti C, Silva JS, Ferreira SH, Cunha FQ. Tumour necrosis factor-alpha and leukotriene B(4) mediate the neutrophil migration in immune inflammation. British Journal of Pharmacology. 134: 1619-28. PMID 11739237 DOI: 10.1038/sj.bjp.0704403 |
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Tavares-Murta BM, Machado JS, Ferreira SH, Cunha FQ. Nitric oxide mediates the inhibition of neutrophil migration induced by systemic administration of LPS. Inflammation. 25: 247-53. PMID 11580101 DOI: 10.1023/A:1010927921018 |
0.333 |
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| 2002 |
Filho AB, Martins MA, Campos-Filho WO, NIcolini EA, Tavares-Murta B, Cunha FQ. “Punctual” Determination Of Cytokines And/Or Nitric Oxide Should Not Be Used As A Prognostic Indicator In Severe Sepsis: 467 Critical Care Medicine. 30. DOI: 10.1097/00003246-200212001-00385 |
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| 2002 |
RIBEIRO R, FREITAS H, CAMPOS M, SANTOS C, FIGUEIREDO F, BRITO G, CUNHA F. Tumor Necrosis Factor-α and Interleukin-1β Mediate the Production of Nitric Oxide Involved in the Pathogenesis of Ifosfamide Induced Hemorrhagic Cystitis in Mice Journal of Urology. 167: 2229-2234. DOI: 10.1016/S0022-5347(05)65134-8 |
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Leung BP, Culshaw S, Gracie JA, Hunter D, Canetti CA, Campbell C, Cunha F, Liew FY, McInnes IB. A role for IL-18 in neutrophil activation. Journal of Immunology (Baltimore, Md. : 1950). 167: 2879-86. PMID 11509635 DOI: 10.4049/Jimmunol.167.5.2879 |
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Steiner AA, Branco LG, Cunha FQ, Ferreira SH. Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity. British Journal of Pharmacology. 132: 1673-82. PMID 11309238 DOI: 10.1038/Sj.Bjp.0704014 |
0.447 |
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| 2001 |
Brito GA, Saraiva SN, Falcão JL, Vale ML, Lima AA, Cunha FQ, Ribeiro RA. Dual effect of cAMP on the writhing response in mice. European Journal of Pharmacology. 416: 223-30. PMID 11290372 DOI: 10.1016/S0014-2999(01)00813-5 |
0.382 |
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Parada CA, Tambeli CH, Cunha FQ, Ferreira SH. The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception. Neuroscience. 102: 937-944. PMID 11182255 DOI: 10.1016/S0306-4522(00)00523-6 |
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| 2000 |
Machado FS, Martins GA, Aliberti JCS, Mestriner FLAC, Cunha FQ, Silva JS. Trypanosoma cruzi-Infected Cardiomyocytes Produce Chemokines and Cytokines That Trigger Potent Nitric Oxide-Dependent Trypanocidal Activity Circulation. 102: 3003-3008. PMID 11113053 DOI: 10.1161/01.Cir.102.24.3003 |
0.575 |
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| 2000 |
Rodrigues ACP, Cara DC, Fretez SHGG, Cunha FQ, Vieira EC, Nicoli JR, Vieira LQ. Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice Journal of Applied Microbiology. 89: 404-414. PMID 11021572 DOI: 10.1046/J.1365-2672.2000.01128.X |
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|
| 2000 |
Cunha JM, Cunha FQ, Poole S, Ferreira SH. Cytokine-mediated inflammatory hyperalgesia limited by interleukin-1 receptor antagonist. British Journal of Pharmacology. 130: 1418-24. PMID 10903985 DOI: 10.1038/Sj.Bjp.0703434 |
0.394 |
|
| 2000 |
Francischi JN, Yokoro CM, Poole S, Tafuri WL, Cunha FQ, Teixeira MM. Anti-inflammatory and analgesic effects of the phosphodiesterase 4 inhibitor rolipram in a rat model of arthritis. European Journal of Pharmacology. 399: 243-9. PMID 10884526 DOI: 10.1016/S0014-2999(00)00330-7 |
0.417 |
|
| 2000 |
Ribeiro RA, Vale ML, Ferreira SH, Cunha FQ. Analgesic effect of thalidomide on inflammatory pain. European Journal of Pharmacology. 391: 97-103. PMID 10720640 DOI: 10.1016/S0014-2999(99)00918-8 |
0.443 |
|
| 2000 |
Ribeiro RA, Vale ML, Thomazzi SM, Paschoalato AB, Poole S, Ferreira SH, Cunha FQ. Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice. European Journal of Pharmacology. 387: 111-8. PMID 10633169 DOI: 10.1016/S0014-2999(99)00790-6 |
0.405 |
|
| 1999 |
Garcia SB, Paula JS, Giovannetti GS, Zenha F, Ramalho EM, Zucoloto S, Silva JS, Cunha FQ. Nitric oxide is involved in the lesions of the peripheral autonomic neurons observed in the acute phase of experimental Trypanosoma cruzi infection. Experimental Parasitology. 93: 191-7. PMID 10600444 DOI: 10.1006/Expr.1999.4451 |
0.487 |
|
| 1999 |
Martins GA, Vieira LQ, Cunha FQ, Silva JS. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infection and Immunity. 67: 3864-71. PMID 10417150 DOI: 10.1128/Iai.67.8.3864-3871.1999 |
0.534 |
|
| 1999 |
Romão PR, Fonseca SG, Hothersall JS, Noronha-Dutra AA, Ferreira SH, Cunha FQ. Glutathione protects macrophages and Leishmania major against nitric oxide-mediated cytotoxicity. Parasitology. 559-66. PMID 10406034 DOI: 10.1017/S0031182099004278 |
0.365 |
|
| 1999 |
Cunha FQ, Teixera MM, Ferreira SH. Pharmacological modulation of secondary mediator systems–cyclic AMP and cyclic GMP–on inflammatory hyperalgesia British Journal of Pharmacology. 127: 671-678. PMID 10401557 DOI: 10.1038/Sj.Bjp.0702601 |
0.446 |
|
| 1999 |
Fierro IM, Nascimento-DaSilva V, Arruda MA, Freitas MS, Plotkowski MC, Cunha FQ, Barja-Fidalgo C. Induction of NOS in rat blood PMN in vivo and in vitro: modulation by tyrosine kinase and involvement in bactericidal activity. Journal of Leukocyte Biology. 65: 508-14. PMID 10204580 DOI: 10.1002/Jlb.65.4.508 |
0.366 |
|
| 1999 |
Poole S, Lorenzetti BB, Cunha JM, Cunha FQ, Ferreira SH. Bradykinin B1 and B2 receptors, tumour necrosis factor α and inflammatory hyperalgesia British Journal of Pharmacology. 126: 649-656. PMID 10188975 DOI: 10.1038/Sj.Bjp.0702347 |
0.331 |
|
| 1999 |
Sakamoto M, Dias-Baruffi M, Santos-de-Oliveira R, Cunha FQ, Roque-Barreira MC. An intravascular chemoattractant lectin inhibits neutrophil migration. Glycoconjugate Journal. 15: 531-3. PMID 9881757 DOI: 10.1023/A:1006947306260 |
0.409 |
|
| 1998 |
Tavares-Murta BM, Cunha FQ, Ferreira SH. The intravenous administration of tumor necrosis factor alpha, interleukin 8 and macrophage-derived neutrophil chemotactic factor inhibits neutrophil migration by stimulating nitric oxide production. British Journal of Pharmacology. 124: 1369-74. PMID 9723947 DOI: 10.1038/Sj.Bjp.0701965 |
0.436 |
|
| 1998 |
Oliveira SH, Fonseca SG, Romão PR, Ferreira SH, Cunha FQ. Nitric oxide mediates the microbicidal activity of eosinophils. Memorias Do Instituto Oswaldo Cruz. 233-5. PMID 9698941 DOI: 10.1590/S0074-02761997000800034 |
0.309 |
|
| 1998 |
Oliveira SH, Faccioli LH, Ferreira SH, Cunha FQ. Participation of interleukin-5, interleukin-8 and leukotriene B4 in eosinophil accumulation in two different experimental models. Memorias Do Instituto Oswaldo Cruz. 205-10. PMID 9698935 DOI: 10.1590/S0074-02761997000800028 |
0.422 |
|
| 1997 |
Cecilio CA, Costa EH, Ucelli P, Chaves CA, Toffoli MC, Flores CA, Cunha FQ, Ferreira SH, Tamashiro WM. The neutrophil migration induced by tumour necrosis factor alpha in mice is unaffected by glucocorticoids. Mediators of Inflammation. 6: 46-52. PMID 18472833 DOI: 10.1080/09629359791929 |
0.471 |
|
| 1997 |
Souza MHLP, Melo-Filho AA, Rocha MFG, Lyerly DM, Cunha FQ, Lima AAM, Ribeiro RA. The involvement of macrophage‐derived tumour necrosis factor and lipoxygenase products on the neutrophil recruitment induced by Clostridium difficile toxin B Immunology. 91: 281-288. PMID 9227329 DOI: 10.1046/J.1365-2567.1997.00243.X |
0.424 |
|
| 1997 |
Ferreira SH, Cunha FQ, Lorenzetti BB, Michelin MA, Perretti M, Flower RJ, Poole S. Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. British Journal of Pharmacology. 121: 883-8. PMID 9222544 DOI: 10.1038/Sj.Bjp.0701211 |
0.436 |
|
| 1997 |
Filho AAM, Souza MHLP, Lyerly DM, Cunha FQ, Lima AAM, Ribeiro RA. Role of tumor necrosis factor and nitric oxide in the cytotoxic effects of Clostridium difficile toxin A and toxin B on macrophages Toxicon. 35: 743-752. PMID 9203299 DOI: 10.1016/S0041-0101(96)00172-9 |
0.404 |
|
| 1997 |
Hothersall JS, Cunha FQ, Neild GH, Norohna-Dutra AA. Induction of nitric oxide synthesis in J774 cells lowers intracellular glutathione: effect of modulated glutathione redox status on nitric oxide synthase induction. The Biochemical Journal. 477-81. PMID 9065766 DOI: 10.1042/Bj3220477 |
0.346 |
|
| 1997 |
Ribeiro RA, Souza-Filho MV, Souza MH, Oliveira SH, Costa CH, Cunha FQ, Ferreira HS. Role of resident mast cells and macrophages in the neutrophil migration induced by LTB4, fMLP and C5a des arg. International Archives of Allergy and Immunology. 112: 27-35. PMID 8980461 DOI: 10.1159/000237427 |
0.346 |
|
| 1997 |
Crosara-Alberto DP, Cunha FQ, Ferreira SH. BRADYKININ INDUCES MEMBRANE AND SOLUBLE TNF-α PRODUCTION BY PERITONEAL MURINE MACROPHAGES. Shock. 7: 36. DOI: 10.1097/00024382-199703001-00145 |
0.338 |
|
| 1996 |
Fierro IM, Barja‐Fidalgo C, Cunha FQ, Ferreira SH. The involvement of nitric oxide in the anti-Candida albicans activity of rat neutrophils. Immunology. 89: 295-300. PMID 8943729 DOI: 10.1046/J.1365-2567.1996.D01-742.X |
0.331 |
|
| 1996 |
Oliveira SH, Faccioli LH, Cunha FQ, Ferreira SH. Participation of lnterleukin-5 and lnterleukin-8 in the Eosinophil Migration Induced by a Large Volume of Saline International Archives of Allergy and Immunology. 111: 245-252. DOI: 10.1159/000237374 |
0.352 |
|
| 1995 |
Zampronio AR, Silva CA, Cunha FQ, Ferreira SH, Pelá IR, Souza GE. Indomethacin blocks the febrile response induced by interleukin-8 in rabbits. The American Journal of Physiology. 269: R1469-74. PMID 8594951 DOI: 10.1152/Ajpregu.1995.269.6.R1469 |
0.403 |
|
| 1995 |
Ribeiro RA, Flores CA, Cunha FQ, Ferreira SH, Lucca FLD. Partial characterization of the RNA from LPS-stimulated macrophages that induces the release of chemotactic cytokines by resident macrophages. Molecular and Cellular Biochemistry. 148: 105-113. PMID 8594414 DOI: 10.1007/Bf00928147 |
0.336 |
|
| 1995 |
Silva JS, Vespa GN, Cardoso MA, Aliberti JC, Cunha FQ. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages. Infection and Immunity. 63: 4862-7. PMID 7591147 DOI: 10.1128/Iai.63.12.4862-4867.1995 |
0.542 |
|
| 1995 |
Poole S, Cunha FQ, Selkirk S, Lorenzetti BB, Ferreira SH. Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. British Journal of Pharmacology. 115: 684-8. PMID 7582491 DOI: 10.1038/Sj.Bjp.0702266 |
0.405 |
|
| 1995 |
Fierro I, Barja-Fidalgo C, Cunha F, Ferreira S. The involvement of nitric oxide and superoxide anion in the anti-Candida albicans activity of rat peritoneal neutrophils Pharmacological Research. 31: 66. DOI: 10.1016/1043-6618(95)86522-5 |
0.312 |
|
| 1994 |
Zampronio AR, Souza GE, Silva CA, Cunha FQ, Ferreira SH. Interleukin-8 induces fever by a prostaglandin-independent mechanism. The American Journal of Physiology. 266: R1670-4. PMID 8203649 DOI: 10.1152/Ajpregu.1994.266.5.R1670 |
0.395 |
|
| 1994 |
Assreuy J, Cunha FQ, Epperlein M, Noronha-Dutra A, O'Donnell CA, Liew FY, Moncada S. Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major. European Journal of Immunology. 24: 672-6. PMID 8125136 DOI: 10.1002/Eji.1830240328 |
0.363 |
|
| 1994 |
Motta JIBd, Cunha FQ, Vargaftig BB, Ferreira SH. Drug modulation of antigen‐induced paw oedema in guinea‐pigs: effects of lipopolysaccharide, tumour necrosis factor and leucocyte depletion British Journal of Pharmacology. 112: 111-116. PMID 8032630 DOI: 10.1111/J.1476-5381.1994.Tb13038.X |
0.424 |
|
| 1993 |
Ferreira SH, Lorenzetti BB, Cunha FQ, Poole S. Bradykinin release of TNF-alpha plays a key role in the development of inflammatory hyperalgesia. Agents and Actions. C7-9. PMID 8317326 DOI: 10.1007/Bf01991120 |
0.453 |
|
| 1993 |
Dias-Baruffi M, Cunha FQ, Ferreira SH, Roque-Barreira MC. Macrophage-released neutrophil chemotactic factor (MNCF) induces PMN-neutrophil migration through lectin-like activity. Agents and Actions. C54-6. PMID 8317322 DOI: 10.1007/Bf01991135 |
0.42 |
|
| 1993 |
Cunha FQ, Boukili MA, da Motta JI, Vargaftig BB, Ferreira SH. Blockade by fenspiride of endotoxin-induced neutrophil migration in the rat. European Journal of Pharmacology. 238: 47-52. PMID 8104802 DOI: 10.1016/0014-2999(93)90503-A |
0.404 |
|
| 1993 |
Cunha FQ, Assreuy J, Xu D, Charles I, Liew FY, Moncada S. Repeated induction of nitric oxide synthase and leishmanicidal activity in murine macrophages. European Journal of Immunology. 23: 1385-1388. PMID 7684689 DOI: 10.1002/Eji.1830230631 |
0.336 |
|
| 1993 |
Assreuy J, Cunha FQ, Liew FY, Moncada S. Feedback inhibition of nitric oxide synthase activity by nitric oxide British Journal of Pharmacology. 108: 833-837. PMID 7682140 DOI: 10.1111/J.1476-5381.1993.Tb12886.X |
0.338 |
|
| 1993 |
Tavares-Murta BM, Lefort J, Cunha FQ, Ferreira SH, Vargaftig BB. Interference of a neutrophil recruitment inhibitory factor upon the accumulation of inflammatory cells and airway hyperreactivity in sensitized guinea-pigs after intranasal antigen challenge. British Journal of Pharmacology. 108: 538-43. PMID 7680596 DOI: 10.1111/J.1476-5381.1993.Tb12837.X |
0.414 |
|
| 1992 |
Barja-Fidalgo C, Carlini CR, Guimarães JA, Flores CA, Cunha FQ, Ferreira SH. Role of resident macrophages in canatoxin-induced in vivo neutrophil migration. Inflammation. 16: 1-12. PMID 1544678 DOI: 10.1007/Bf00917510 |
0.441 |
|
| 1992 |
Cunha FQ, Poole S, Lorenzetti BB, Ferreira SH. The pivotal role of tumour necrosis factor α in the development of inflammatory hyperalgesia British Journal of Pharmacology. 107: 660-664. PMID 1472964 DOI: 10.1111/J.1476-5381.1992.Tb14503.X |
0.406 |
|
| 1992 |
Cunha FQ, Mohcada S, Liew FY. Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages Biochemical and Biophysical Research Communications. 182: 1155-1159. PMID 1371674 DOI: 10.1016/0006-291X(92)91852-H |
0.412 |
|
| 1991 |
Cunha FQ, Lorenzetti BB, Poole S, Ferreira SH. Interleukin‐8 as a mediator of sympathetic pain British Journal of Pharmacology. 104: 765-767. PMID 1797337 DOI: 10.1111/J.1476-5381.1991.Tb12502.X |
0.407 |
|
| 1990 |
Faccioli LH, Souza GE, Cunha FQ, Poole S, Ferreira SH. Recombinant interleukin-1 and tumor necrosis factor induce neutrophil migration "in vivo" by indirect mechanisms. Agents and Actions. 30: 344-9. PMID 2201176 DOI: 10.1007/Bf01966298 |
0.403 |
|
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