Year |
Citation |
Score |
2023 |
Dias C, Fernandes E, Barbosa RM, Laranjinha J, Ledo A. Astrocytic aerobic glycolysis provides lactate to support neuronal oxidative metabolism in the hippocampus. Biofactors (Oxford, England). PMID 37070143 DOI: 10.1002/biof.1951 |
0.814 |
|
2023 |
Reva K, Laranjinha J, Rocha BS. Epigenetic Modifications Induced by the Gut Microbiota May Result from What We Eat: Should We Talk about in Health and Disease? Metabolites. 13. PMID 36984815 DOI: 10.3390/metabo13030375 |
0.696 |
|
2022 |
Fraga CG, Trostchansky A, Rocha BS, Laranjinha J, Rubbo H, Galleano M. (Poly)phenols and nitrolipids: Relevant participants in nitric oxide metabolism. Molecular Aspects of Medicine. 89: 101158. PMID 36517273 DOI: 10.1016/j.mam.2022.101158 |
0.746 |
|
2021 |
Lourenço CF, Laranjinha J. Nitric Oxide Pathways in Neurovascular Coupling Under Normal and Stress Conditions in the Brain: Strategies to Rescue Aberrant Coupling and Improve Cerebral Blood Flow. Frontiers in Physiology. 12: 729201. PMID 34744769 DOI: 10.3389/fphys.2021.729201 |
0.322 |
|
2021 |
Mancini G, Dias C, Lourenço CF, Laranjinha J, de Bem A, Ledo A. A High Fat/Cholesterol Diet Recapitulates Some Alzheimer's Disease-Like Features in Mice: Focus on Hippocampal Mitochondrial Dysfunction. Journal of Alzheimer's Disease : Jad. PMID 34219714 DOI: 10.3233/JAD-210122 |
0.728 |
|
2020 |
Rodrigues MS, Ferreira C, Dias C, Pliássova A, Souza L, Ledo A, Laranjinha J, Cunha RA, Köfalvi A. An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease. The European Journal of Neuroscience. PMID 32813905 DOI: 10.1111/Ejn.14944 |
0.763 |
|
2020 |
Laranjinha J, Nunes C, Ledo A, Lourenço C, Rocha B, Barbosa RM. The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling. Neurochemical Research. PMID 32193753 DOI: 10.1007/S11064-020-03015-0 |
0.82 |
|
2020 |
Rocha BS, Laranjinha J. Nitrate from diet might fuel gut microbiota metabolism: Minding the gap between redox signaling and inter-kingdom communication. Free Radical Biology & Medicine. PMID 32045656 DOI: 10.1016/J.Freeradbiomed.2020.02.001 |
0.736 |
|
2019 |
Ledo A, Rocha BS, Laranjinha J. Bioactive Lipids and the Gut-Brain Axis: Diet as a Modulator of Bioactivity and Diversity of Lipids in the Brain. Advances in Experimental Medicine and Biology. 1127: 147-168. PMID 31140177 DOI: 10.1007/978-3-030-11488-6_10 |
0.688 |
|
2019 |
Rocha BS, Correia MG, Pereira A, Henriques I, Da Silva GJ, Laranjinha J. Inorganic nitrate prevents the loss of tight junction proteins and modulates inflammatory events induced by broad-spectrum antibiotics: A role for intestinal microbiota? Nitric Oxide : Biology and Chemistry. PMID 30980891 DOI: 10.1016/J.Niox.2019.04.001 |
0.724 |
|
2019 |
Ledo A, Lourenço CF, Laranjinha J, Gerhardt GA, Barbosa RM. Concurrent recording of neurometabolic changes and local field potential in the central nervous system of awake-behaving rodent models of epilepsy Annals of Medicine. 51: 24-24. DOI: 10.1080/07853890.2018.1560060 |
0.73 |
|
2018 |
Lourenço CF, Ledo A, Caetano M, Barbosa RM, Laranjinha J. Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus. Frontiers in Physiology. 9: 913. PMID 30065657 DOI: 10.3389/Fphys.2018.00913 |
0.787 |
|
2018 |
Ledo A, Barbosa RM, Laranjinha J. Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal Slices. Methods in Molecular Biology (Clifton, N.J.). 1782: 89-107. PMID 29850995 DOI: 10.1007/978-1-4939-7831-1_5 |
0.783 |
|
2018 |
Dias C, Lourenço CF, Barbosa RM, Laranjinha J, Ledo A. Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Analytical Biochemistry. 551: 43-50. PMID 29753719 DOI: 10.1016/J.Ab.2018.05.010 |
0.787 |
|
2018 |
Ferreira NR, Ledo A, Laranjinha J, Gerhardt GA, Barbosa RM. Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays. Bioelectrochemistry (Amsterdam, Netherlands). 121: 142-150. PMID 29413864 DOI: 10.1016/J.Bioelechem.2018.01.009 |
0.753 |
|
2018 |
Laranjinha J, Lourenço C, Ledo A, Dias C, Ferreira N, Barbosa RM. NITRIC OXIDE MEDIATED NEUROVASCULAR COUPLING IN AGING AND ALZHEIMER'S DISEASE Pathophysiology. 25: 189. DOI: 10.1016/J.Pathophys.2018.07.068 |
0.803 |
|
2018 |
Laranjinha J, Lourenço CF, Ferreira NR, Barbosa RM. Neurovascular coupling mediated by neuronal nitric oxide in hippocampus and the redox cycle of ascorbate and nitrite Free Radical Biology and Medicine. 128: S132. DOI: 10.1016/J.Freeradbiomed.2018.10.349 |
0.659 |
|
2018 |
Nunes C, Freitas V, Laranjinha J. Modulation of tight junctions in intestinal epithelial cells by red wine polyphenols Free Radical Biology and Medicine. 120: S149. DOI: 10.1016/J.Freeradbiomed.2018.04.491 |
0.34 |
|
2018 |
Ledo A, Lourenço C, Nunes C, Santos D, Laranjinha J, Barbosa R. Electrochemical (bio)sensors for high-resolution measurements of hydrogen peroxide in biological media Free Radical Biology and Medicine. 120: S145. DOI: 10.1016/J.Freeradbiomed.2018.04.476 |
0.759 |
|
2018 |
Gonçalves J, Dias C, Ferreira N, Ledo A, Barbosa R, Laranjinha J. The interplay of nitrite:ascorbate:nitric oxide and its contribution to neurovascular coupling in the hippocampus Free Radical Biology and Medicine. 120: S142. DOI: 10.1016/J.Freeradbiomed.2018.04.469 |
0.82 |
|
2018 |
Dias C, Lourenço CF, Barbosa RM, Laranjinha J, Ledo A. Age-dependent impairment of the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic mouse model of Alzheimer's disease Free Radical Biology and Medicine. 120: S139. DOI: 10.1016/J.Freeradbiomed.2018.04.459 |
0.815 |
|
2018 |
Lourenço CF, Ledo A, Caetano M, Barbosa RM, Laranjinha J. Age-dependent changes of neurovascular coupling and brain metabolism in Fischer 344 rats Free Radical Biology and Medicine. 120: S43. DOI: 10.1016/J.Freeradbiomed.2018.04.145 |
0.795 |
|
2018 |
Rocha BS, Pereira A, Da Silva GJ, Laranjinha J. Dietary nitrate modulates gut microbiota profile and prevents the activation of mucosal inflammatory pathways induced by broad-spectrum antibiotics Free Radical Biology and Medicine. 120: S36. DOI: 10.1016/J.Freeradbiomed.2018.04.124 |
0.31 |
|
2018 |
Ferreira NR, Lourenço CF, Barbosa RM, Laranjinha J. Nitric oxide mediated neurovascular coupling is maintained under hypoxia through ascorbate-dependent nitrite reduction to NO: An in vivo study in the hippocampus Free Radical Biology and Medicine. 120: S30. DOI: 10.1016/J.Freeradbiomed.2018.04.104 |
0.429 |
|
2018 |
Mancini G, Dias C, Lourenço C, Barbosa RM, Laranjinha J, de Bem AF, Ledo A. High-fat and high cholesterol diet induces Alzheimer's like disease in mice Free Radical Biology and Medicine. 120: S25. DOI: 10.1016/J.Freeradbiomed.2018.04.027 |
0.793 |
|
2018 |
Ledo A, Lourenço CF, Laranjinha J, Gerhardt GA, Barbosa RM. Concurrent measurements of neurochemical and electrophysiological activity with microelectrode arrays: New perspectives for constant potential amperometry Current Opinion in Electrochemistry. 12: 129-140. DOI: 10.1016/J.Coelec.2018.05.018 |
0.734 |
|
2017 |
Ledo A, Lourenço CF, Laranjinha J, Gerhardt GA, Barbosa RM. Combined in vivo Amperometric Oximetry and Electrophysiology in a Single Sensor - a Tool for Epilepsy Research. Analytical Chemistry. PMID 29067809 DOI: 10.1021/Acs.Analchem.7B03452 |
0.744 |
|
2017 |
Lourenço CF, Ledo A, Gerhardt GA, Laranjinha J, Barbosa RM. Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays. Scientific Reports. 7: 6764. PMID 28754993 DOI: 10.1038/S41598-017-07119-6 |
0.758 |
|
2017 |
Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, ... ... Laranjinha J, et al. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology. 13: 94-162. PMID 28577489 DOI: 10.1016/J.Redox.2017.05.007 |
0.64 |
|
2017 |
Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration. Free Radical Biology & Medicine. 108: 668-682. PMID 28435052 DOI: 10.1016/J.Freeradbiomed.2017.04.026 |
0.798 |
|
2017 |
Ledo A, Lourenço CF, Laranjinha J, Brett CM, Gerhardt GA, Barbosa RM. Ceramic-Based Multisite Platinum Microelectrode Arrays: Morphological Characteristics and Electrochemical Performance for Extracellular Oxygen Measurements in Brain Tissue. Analytical Chemistry. 89: 1674-1683. PMID 28208270 DOI: 10.1021/Acs.Analchem.6B03772 |
0.748 |
|
2017 |
Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling. Experimental Neurology. 291: 36-43. PMID 28161255 DOI: 10.1016/J.Expneurol.2017.01.013 |
0.77 |
|
2017 |
Nunes C, Almeida L, Barbosa RM, Laranjinha J. Luteolin suppresses the JAK/STAT pathway in a cellular model of intestinal inflammation. Food & Function. 8: 387-396. PMID 28067377 DOI: 10.1039/C6Fo01529H |
0.613 |
|
2017 |
Laranjinha J, Marques C, Ledo A, Dias C, Ferreira N, Barbosa R. Regulation of neurovascular coupling in the brain by nitrite Free Radical Biology and Medicine. 108: S11. DOI: 10.1016/J.Freeradbiomed.2017.04.065 |
0.798 |
|
2016 |
Nunes C, Teixeira N, Serra D, Freitas V, Almeida L, Laranjinha J. Red wine polyphenol extract efficiently protects intestinal epithelial cells from inflammation opposite modulation of JAK/STAT and Nrf2 pathways. Toxicology Research. 5: 53-65. PMID 30090326 DOI: 10.1039/C5Tx00214A |
0.322 |
|
2016 |
Rocha BS, Nunes C, Laranjinha J. Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome. The International Journal of Biochemistry & Cell Biology. 81: 393-402. PMID 27989963 DOI: 10.1016/J.Biocel.2016.10.021 |
0.739 |
|
2016 |
Rocha BS, Correia MG, Fernandes RC, Gonçalves JS, Laranjinha J. Dietary nitrite induces occludin nitration in the stomach. Free Radical Research. 1-19. PMID 27607739 DOI: 10.1080/10715762.2016.1234049 |
0.777 |
|
2016 |
Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A. Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of Aging. 46: 84-95. PMID 27460153 DOI: 10.1016/J.Neurobiolaging.2016.06.012 |
0.817 |
|
2016 |
Rocha BS, Lundberg JO, Radi R, Laranjinha J. Role of nitrite, urate and pepsin in the gastroprotective effects of saliva. Redox Biology. 8: 407-14. PMID 27156250 DOI: 10.1016/J.Redox.2016.04.002 |
0.747 |
|
2016 |
Lourenço CF, Ledo A, Laranjinha J, Gerhardt GA, Barbosa RM. Microelectrode array biosensor for high-resolution measurements of extracellular glucose in the brain Sensors and Actuators B: Chemical. 237: 298-307. DOI: 10.1016/J.Snb.2016.06.083 |
0.747 |
|
2016 |
Santos RM, Rodrigues MS, Laranjinha J, Barbosa RM. Corrigendum to 'Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brain' [Biosens. Bioelectron. 44 (2013) 152-159]. doi: 10.1016/j.bios.2013.01.015 Biosensors and Bioelectronics. 79: 945. DOI: 10.1016/J.Bios.2015.10.086 |
0.621 |
|
2015 |
Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J. Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 103. PMID 26074816 DOI: 10.3389/Fnagi.2015.00103 |
0.807 |
|
2015 |
Ferreira NR, Lourenço CF, Barbosa RM, Laranjinha J. Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: a novel functional interplay. Brain Research Bulletin. 114: 13-9. PMID 25783673 DOI: 10.1016/J.Brainresbull.2015.03.002 |
0.677 |
|
2015 |
Santos RM, Laranjinha J, Barbosa RM, Sirota A. Simultaneous measurement of cholinergic tone and neuronal network dynamics in vivo in the rat brain using a novel choline oxidase based electrochemical biosensor. Biosensors & Bioelectronics. 69: 83-94. PMID 25706061 DOI: 10.1016/J.Bios.2015.02.003 |
0.62 |
|
2015 |
Pereira C, Barbosa RM, Laranjinha J. Dietary nitrite induces nitrosation of the gastric mucosa: the protective action of the mucus and the modulatory effect of red wine. The Journal of Nutritional Biochemistry. 26: 476-83. PMID 25701398 DOI: 10.1016/J.Jnutbio.2014.12.004 |
0.819 |
|
2015 |
Rocha BS, Gago B, Barbosa RM, Cavaleiro C, Laranjinha J. Ethyl nitrite is produced in the human stomach from dietary nitrate and ethanol, releasing nitric oxide at physiological pH: potential impact on gastric motility. Free Radical Biology & Medicine. 82: 160-6. PMID 25645954 DOI: 10.1016/J.Freeradbiomed.2015.01.021 |
0.812 |
|
2015 |
Ledo A, Lourenço CF, Caetano M, Barbosa RM, Laranjinha J. Age-associated changes of nitric oxide concentration dynamics in the central nervous system of Fisher 344 rats. Cellular and Molecular Neurobiology. 35: 33-44. PMID 25274046 DOI: 10.1007/S10571-014-0115-0 |
0.778 |
|
2015 |
Santos RM, Lourenço CF, Gerhardt GA, Cadenas E, Laranjinha J, Barbosa RM. Corrigendum to “Evidence for a pathway that facilitates nitric oxide diffusion in the brain” [Neurochem. Int. 59 (2011) 90–96] Neurochemistry International. 91: 78. DOI: 10.1016/J.Neuint.2015.11.004 |
0.643 |
|
2015 |
Ferreira N, Lourenço C, Ana L, Rui B, Laranjinha J. Nitrite supports neurovascular coupling via redox cycling with ascorbate Free Radical Biology and Medicine. 86: S16. DOI: 10.1016/J.Freeradbiomed.2015.07.070 |
0.462 |
|
2015 |
Rocha BS, Correia MG, Pereira A, Silva GJ, Barbosa RM, Laranjinha J. Gut microbiome is rescued by dietary nitrate during dysbiosis: the impact on epithelial fence function and inflammatory pathways during antibiotic therapy Free Radical Biology and Medicine. 86: S8. DOI: 10.1016/J.Freeradbiomed.2015.07.039 |
0.618 |
|
2014 |
Dias C, Barbosa RM, Laranjinha J, Ledo A. Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices. Free Radical Biology & Medicine. 75: S37. PMID 26461355 DOI: 10.1016/J.Freeradbiomed.2014.10.780 |
0.79 |
|
2014 |
Rocha B, Correia M, Barbosa R, Laranjinha J. A dietary-driven redox modulation of gut microbiome-host interactions: the rescue of epithelial barrier and mucus production during dysbiosis by dietary nitrate. Free Radical Biology & Medicine. 75: S36-7. PMID 26461352 DOI: 10.1016/J.Freeradbiomed.2014.10.779 |
0.783 |
|
2014 |
Rocha BS, Nunes C, Pereira C, Barbosa RM, Laranjinha J. A shortcut to wide-ranging biological actions of dietary polyphenols: modulation of the nitrate-nitrite-nitric oxide pathway in the gut. Food & Function. 5: 1646-52. PMID 24912104 DOI: 10.1039/C4Fo00124A |
0.813 |
|
2014 |
Laranjinha J. Nutrition and ageing: from phenomenological observations to molecular mechanisms. Genes & Nutrition. 9: 407. PMID 24903833 DOI: 10.1007/S12263-014-0407-5 |
0.319 |
|
2014 |
Lourenço CF, Santos RM, Barbosa RM, Cadenas E, Radi R, Laranjinha J. Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide. Free Radical Biology & Medicine. 73: 421-9. PMID 24887095 DOI: 10.1016/J.Freeradbiomed.2014.05.021 |
0.649 |
|
2014 |
Lourenço CF, Ferreira NR, Santos RM, Lukacova N, Barbosa RM, Laranjinha J. The pattern of glutamate-induced nitric oxide dynamics in vivo and its correlation with nNOS expression in rat hippocampus, cerebral cortex and striatum. Brain Research. 1554: 1-11. PMID 24495843 DOI: 10.1016/J.Brainres.2014.01.030 |
0.395 |
|
2014 |
Laranjinha J, Rocha B, Pereira C, Nunes C, Barbosa R. An alternative pathway to widespread health benefits of dietary polyphenols: The nitrate-nitrite-nitric oxide pathway in the gut Planta Medica. 80. DOI: 10.1055/S-0034-1394483 |
0.799 |
|
2014 |
Lourenço CF, Barbosa RM, Laranjinha J. Nitric Oxide-Mediated Neurovascular Coupling Is Impaired in the Triple-Transgenic Mouse Model of Alzheimer’s Disease Due to Cerebrovascular Dysfunction Free Radical Biology and Medicine. 76: S25. DOI: 10.1016/J.Freeradbiomed.2014.10.479 |
0.646 |
|
2013 |
Pereira C, Ferreira NR, Rocha BS, Barbosa RM, Laranjinha J. The redox interplay between nitrite and nitric oxide: From the gut to the brain. Redox Biology. 1: 276-84. PMID 24024161 DOI: 10.1016/J.Redox.2013.04.004 |
0.827 |
|
2013 |
Oliveira SC, Santarino IB, Enache TA, Nunes C, Laranjinha J, Barbosa RM, Oliveira-Brett AM. Human colon adenocarcinoma HT-29 cell: electrochemistry and nicotine stimulation. Bioelectrochemistry (Amsterdam, Netherlands). 94: 30-8. PMID 23774106 DOI: 10.1016/J.Bioelechem.2013.05.004 |
0.604 |
|
2013 |
Santos RM, Rodrigues MS, Laranjinha J, Barbosa RM. Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brain. Biosensors & Bioelectronics. 44: 152-9. PMID 23419387 DOI: 10.1016/J.Bios.2013.01.015 |
0.624 |
|
2013 |
Rocha BS, Gago B, Barbosa RM, Lundberg JO, Mann GE, Radi R, Laranjinha J. Pepsin is nitrated in the rat stomach, acquiring antiulcerogenic activity: a novel interaction between dietary nitrate and gut proteins. Free Radical Biology & Medicine. 58: 26-34. PMID 23277149 DOI: 10.1016/J.Freeradbiomed.2012.12.017 |
0.803 |
|
2013 |
Nunes C, Ferreira E, Freitas V, Almeida L, Barbosa RM, Laranjinha J. Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells. Food & Function. 4: 373-83. PMID 23233037 DOI: 10.1039/C2Fo30233K |
0.642 |
|
2013 |
Figueiras E, Oliveira R, Lourenço CF, Campos R, Humeau-Heurtier A, Barbosa RM, Laranjinha J, Requicha Ferreira LF, de Mul FF. Self-mixing microprobe for monitoring microvascular perfusion in rat brain. Medical & Biological Engineering & Computing. 51: 103-12. PMID 23065628 DOI: 10.1007/S11517-012-0973-X |
0.604 |
|
2013 |
Ferreira NR, Santos RM, Laranjinha J, Barbosa RM. Real Time In Vivo Measurement of Ascorbate in the Brain Using Carbon Nanotube-Modified Microelectrodes Electroanalysis. 25: 1757-1763. DOI: 10.1002/Elan.201300053 |
0.622 |
|
2012 |
Laranjinha J, Santos RM, Lourenço CF, Ledo A, Barbosa RM. Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling. Annals of the New York Academy of Sciences. 1259: 10-8. PMID 22758631 DOI: 10.1111/J.1749-6632.2012.06582.X |
0.791 |
|
2012 |
Santos RM, Lourenço CF, Ledo A, Barbosa RM, Laranjinha J. Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration. International Journal of Cell Biology. 2012: 391914. PMID 22719764 DOI: 10.1155/2012/391914 |
0.788 |
|
2012 |
Bretón-Romero R, González de Orduña C, Romero N, Sánchez-Gómez FJ, de Ãlvaro C, Porras A, RodrÃguez-Pascual F, Laranjinha J, Radi R, Lamas S. Critical role of hydrogen peroxide signaling in the sequential activation of p38 MAPK and eNOS in laminar shear stress. Free Radical Biology & Medicine. 52: 1093-100. PMID 22281399 DOI: 10.1016/J.Freeradbiomed.2011.12.026 |
0.327 |
|
2012 |
Rocha BS, Gago B, Barbosa RM, Lundberg JO, Radi R, Laranjinha J. Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling. Free Radical Biology & Medicine. 52: 693-698. PMID 22154654 DOI: 10.1016/J.Freeradbiomed.2011.11.011 |
0.804 |
|
2012 |
Ledo A, Barbosa RM, Laranjinha J. Modulation of cellular respiration by endogenously produced nitric oxide in rat hippocampal slices. Methods in Molecular Biology (Clifton, N.J.). 810: 73-88. PMID 22057561 DOI: 10.1007/978-1-61779-382-0_5 |
0.794 |
|
2012 |
Lourenço⁎ C, Barbosa R, Cadenas E, Radi R, Laranjinha J. Nitric oxide dynamics and dependent neurovascular coupling in a triple-transgenic mouse model of Alzheimer’s disease Free Radical Biology and Medicine. 53: S62. DOI: 10.1016/J.Freeradbiomed.2012.08.549 |
0.639 |
|
2012 |
Rocha⁎ B, Gago B, Barbosa R, Lundberg J, Radi R, Laranjinha J. Pepsin is nitrated in the stomach acquiring anti-ulcerogenic activity: a novel nitrating pathway involving dietary nitrite, gut microbiota and gastric proteins Free Radical Biology and Medicine. 53: S60. DOI: 10.1016/J.Freeradbiomed.2012.08.545 |
0.785 |
|
2012 |
Nunes⁎ C, Freitas V, Barbosa R, Almeida L, Laranjinha J. Red wine protects intestinal epithelial cells from inflammation by activating the Nrf2 pathway and reinforcing tight junctions Free Radical Biology and Medicine. 53: S195. DOI: 10.1016/J.Freeradbiomed.2012.08.409 |
0.593 |
|
2012 |
Laranjinha⁎ J, Lourenço C, Radi R, Cadenas E, Barbosa R. Neurovascular and metabolic coupling: diffusible bridging supported by nitric oxide Free Radical Biology and Medicine. 53: S28-S29. DOI: 10.1016/J.Freeradbiomed.2012.08.132 |
0.645 |
|
2011 |
Nunes C, Barbosa RM, Almeida L, Laranjinha J. Nitric oxide and DOPAC-induced cell death: from GSH depletion to mitochondrial energy crisis. Molecular and Cellular Neurosciences. 48: 94-103. PMID 21708261 DOI: 10.1016/J.Mcn.2011.06.009 |
0.628 |
|
2011 |
Santos RM, Lourenço CF, Gerhardt GA, Cadenas E, Laranjinha J, Barbosa RM. Evidence for a pathway that facilitates nitric oxide diffusion in the brain. Neurochemistry International. 59: 90-6. PMID 21672575 DOI: 10.1016/J.Neuint.2011.05.016 |
0.607 |
|
2011 |
Rocha BS, Gago B, Pereira C, Barbosa RM, Bartesaghi S, Lundberg JO, Radi R, Laranjinha J. Dietary nitrite in nitric oxide biology: a redox interplay with implications for pathophysiology and therapeutics. Current Drug Targets. 12: 1351-63. PMID 21443473 DOI: 10.2174/138945011796150334 |
0.806 |
|
2011 |
Santos RM, Lourenço CF, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J, Barbosa RM. Brain nitric oxide inactivation is governed by the vasculature. Antioxidants & Redox Signaling. 14: 1011-21. PMID 20712398 DOI: 10.1089/Ars.2010.3297 |
0.641 |
|
2011 |
Lourenço CF, Santos R, Barbosa RM, Gerhardt G, Cadenas E, Laranjinha J. In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus. Hippocampus. 21: 622-30. PMID 20169537 DOI: 10.1002/Hipo.20774 |
0.645 |
|
2010 |
Ledo A, Barbosa R, Cadenas E, Laranjinha J. Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices. Free Radical Biology & Medicine. 48: 1044-50. PMID 20100565 DOI: 10.1016/J.Freeradbiomed.2010.01.024 |
0.767 |
|
2010 |
Rocha BS, Gago B, Barbosa RM, Laranjinha J. Diffusion of nitric oxide through the gastric wall upon reduction of nitrite by red wine: physiological impact. Nitric Oxide : Biology and Chemistry. 22: 235-41. PMID 20083218 DOI: 10.1016/J.Niox.2010.01.003 |
0.793 |
|
2009 |
Rocha BS, Gago B, Barbosa RM, Laranjinha J. Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation. Toxicology. 265: 41-8. PMID 19778575 DOI: 10.1016/J.Tox.2009.09.008 |
0.804 |
|
2009 |
Frade JG, Barbosa RM, Laranjinha J. Stimulation of NMDA and AMPA glutamate receptors elicits distinct concentration dynamics of nitric oxide in rat hippocampal slices. Hippocampus. 19: 603-11. PMID 19115375 DOI: 10.1002/Hipo.20536 |
0.629 |
|
2008 |
Nunes C, Almeida L, Laranjinha J. 3,4-Dihydroxyphenylacetic acid (DOPAC) modulates the toxicity induced by nitric oxide in PC-12 cells via mitochondrial dysfunctioning. Neurotoxicology. 29: 998-1007. PMID 18706927 DOI: 10.1016/J.Neuro.2008.07.003 |
0.31 |
|
2008 |
Santos RM, Lourenço CF, Piedade AP, Andrews R, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J, Barbosa RM. A comparative study of carbon fiber-based microelectrodes for the measurement of nitric oxide in brain tissue. Biosensors & Bioelectronics. 24: 704-9. PMID 18657966 DOI: 10.1016/J.Bios.2008.06.034 |
0.595 |
|
2008 |
Barbosa RM, Lourenço CF, Santos RM, Pomerleau F, Huettl P, Gerhardt GA, Laranjinha J. In vivo real-time measurement of nitric oxide in anesthetized rat brain. Methods in Enzymology. 441: 351-67. PMID 18554545 DOI: 10.1016/S0076-6879(08)01220-2 |
0.673 |
|
2008 |
Gago B, Nyström T, Cavaleiro C, Rocha BS, Barbosa RM, Laranjinha J, Lundberg JO. The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions. Free Radical Biology & Medicine. 45: 404-12. PMID 18482590 DOI: 10.1016/J.Freeradbiomed.2008.04.027 |
0.783 |
|
2008 |
Lourenço CF, Gago B, Barbosa RM, de Freitas V, Laranjinha J. LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion. Journal of Agricultural and Food Chemistry. 56: 3798-804. PMID 18454545 DOI: 10.1021/Jf0733259 |
0.785 |
|
2008 |
Frade J, Pope S, Schmidt M, Dringen R, Barbosa R, Pocock J, Laranjinha J, Heales S. Glutamate induces release of glutathione from cultured rat astrocytes--a possible neuroprotective mechanism? Journal of Neurochemistry. 105: 1144-52. PMID 18182055 DOI: 10.1111/J.1471-4159.2008.05216.X |
0.783 |
|
2007 |
Gago B, Lundberg JO, Barbosa RM, Laranjinha J. Red wine-dependent reduction of nitrite to nitric oxide in the stomach. Free Radical Biology & Medicine. 43: 1233-42. PMID 17893036 DOI: 10.1016/J.Freeradbiomed.2007.06.007 |
0.807 |
|
2007 |
Almeida B, Buttner S, Ohlmeier S, Silva A, Mesquita A, Sampaio-Marques B, Osório NS, Kollau A, Mayer B, Leão C, Laranjinha J, Rodrigues F, Madeo F, Ludovico P. NO-mediated apoptosis in yeast. Journal of Cell Science. 120: 3279-88. PMID 17726063 DOI: 10.1242/Jcs.010926 |
0.379 |
|
2007 |
Osório NS, Carvalho A, Almeida AJ, Padilla-Lopez S, Leão C, Laranjinha J, Ludovico P, Pearce DA, Rodrigues F. Nitric oxide signaling is disrupted in the yeast model for Batten disease. Molecular Biology of the Cell. 18: 2755-67. PMID 17475770 DOI: 10.1091/Mbc.E06-11-1053 |
0.384 |
|
2007 |
Laranjinha J, Ledo A. Coordination of physiologic and toxic pathways in hippocampus by nitric oxide and mitochondria. Frontiers in Bioscience : a Journal and Virtual Library. 12: 1094-106. PMID 17127364 DOI: 10.2741/2129 |
0.718 |
|
2006 |
Frank J, Budek A, Lundh T, Parker RS, Swanson JE, Lourenço CF, Gago B, Laranjinha J, Vessby B, Kamal-Eldin A. Dietary flavonoids with a catechol structure increase alpha-tocopherol in rats and protect the vitamin from oxidation in vitro. Journal of Lipid Research. 47: 2718-25. PMID 16951402 DOI: 10.1194/Jlr.M600291-Jlr200 |
0.761 |
|
2005 |
Ledo A, Barbosa RM, Gerhardt GA, Cadenas E, Laranjinha J. Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 17483-8. PMID 16293699 DOI: 10.1073/Pnas.0503624102 |
0.757 |
|
2005 |
Nunes C, Almeida L, Laranjinha J. Synergistic inhibition of respiration in brain mitochondria by nitric oxide and dihydroxyphenylacetic acid (DOPAC). Implications for Parkinson's disease. Neurochemistry International. 47: 173-82. PMID 15893407 DOI: 10.1016/J.Neuint.2005.03.005 |
0.376 |
|
2005 |
Sousa T, Fernandes E, Nunes C, Laranjinha J, Carvalho F, Pinho D, Morato M, Albino-Teixeira A. Scavenging of nitric oxide by an antagonist of adenosine receptors. The Journal of Pharmacy and Pharmacology. 57: 399-404. PMID 15807997 DOI: 10.1211/0022357055614 |
0.345 |
|
2005 |
Antunes F, Nunes C, Laranjinha J, Cadenas E. Redox interactions of nitric oxide with dopamine and its derivatives. Toxicology. 208: 207-12. PMID 15691585 DOI: 10.1016/J.Tox.2004.11.033 |
0.421 |
|
2005 |
Frade J, Ferreira N, Barbosa R, Laranjinha J. Mechanisms of Neuroprotection by Polyphenols Current Medicinal Chemistry-Central Nervous System Agents. 5: 307-318. DOI: 10.2174/156801505774913062 |
0.76 |
|
2005 |
Ferreira NR, Ledo A, Frade JG, Gerhardt GA, Laranjinha J, Barbosa RM. Electrochemical measurement of endogenously produced nitric oxide in brain slices using Nafion/o-phenylenediamine modified carbon fiber microelectrodes Analytica Chimica Acta. 535: 1-7. DOI: 10.1016/J.Aca.2004.12.017 |
0.796 |
|
2004 |
Martins J, Almeida L, Laranjinha J. Simultaneous production of superoxide radical and singlet oxygen by sulphonated chloroaluminum phthalocyanine incorporated in human low-density lipoproteins: implications for photodynamic therapy. Photochemistry and Photobiology. 80: 267-73. PMID 15362945 DOI: 10.1562/2004-03-26-Ra-124.1 |
0.356 |
|
2004 |
Ledo A, Frade J, Barbosa RM, Laranjinha J. Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions. Molecular Aspects of Medicine. 25: 75-89. PMID 15051318 DOI: 10.1016/J.Mam.2004.02.010 |
0.807 |
|
2002 |
Ledo A, Barbosa RM, Frade J, Laranjinha J. Nitric oxide monitoring in hippocampal brain slices using electrochemical methods. Methods in Enzymology. 359: 111-25. PMID 12481564 DOI: 10.1016/S0076-6879(02)59176-X |
0.805 |
|
2002 |
Martins J, Madeira V, Almeida L, Laranjinha J. Photoactivation of phthalocyanine-loaded low density lipoproteins induces a local oxidative stress that propagates to human erythrocytes: protection by caffeic acid. Free Radical Research. 36: 319-28. PMID 12071351 DOI: 10.1080/10715760290019345 |
0.359 |
|
2002 |
Laranjinha J, Cadenas E. Oxidation of DOPAC by nitric oxide: effect of superoxide dismutase. Journal of Neurochemistry. 81: 892-900. PMID 12065648 DOI: 10.1046/J.1471-4159.2002.00900.X |
0.417 |
|
1999 |
Laranjinha J, Cadenas E. Redox cycles of caffeic acid, alpha-tocopherol, and ascorbate: implications for protection of low-density lipoproteins against oxidation. Iubmb Life. 48: 57-65. PMID 10791916 DOI: 10.1080/713803474 |
0.352 |
|
1998 |
Vieira O, Escargueil-Blanc I, Meilhac O, Basile JP, Laranjinha J, Almeida L, Salvayre R, Nègre-Salvayre A. Effect of dietary phenolic compounds on apoptosis of human cultured endothelial cells induced by oxidized LDL. British Journal of Pharmacology. 123: 565-73. PMID 9504398 DOI: 10.1038/Sj.Bjp.0701624 |
0.411 |
|
1998 |
Vieira O, Laranjinha J, Madeira V, Almeida L. Cholesteryl ester hydroperoxide formation in myoglobin-catalyzed low density lipoprotein oxidation: concerted antioxidant activity of caffeic and p-coumaric acids with ascorbate. Biochemical Pharmacology. 55: 333-40. PMID 9484800 DOI: 10.1016/S0006-2952(97)00470-X |
0.396 |
|
1995 |
Laranjinha J, Almeida L, Madeira V. Reduction of ferrylmyoglobin by dietary phenolic acid derivatives of cinnamic acid. Free Radical Biology & Medicine. 19: 329-37. PMID 7557547 DOI: 10.1016/0891-5849(95)00039-Z |
0.323 |
|
1995 |
Laranjinha J, Vieira O, Madeira V, Almeida L. Two related phenolic antioxidants with opposite effects on vitamin E content in low density lipoproteins oxidized by ferrylmyoglobin: consumption vs regeneration. Archives of Biochemistry and Biophysics. 323: 373-81. PMID 7487101 DOI: 10.1006/Abbi.1995.0057 |
0.3 |
|
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