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Muhammad Jbara - Publications

Affiliations: 
2015-2019 Chemistry Technion - Israel Institute of Technology, Haifa, Haifa District, Israel 
 2019- Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Chemical biology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Parisis N, Dans PD, Jbara M, Singh B, Schausi-Tiffoche D, Molina-Serrano D, Brun-Heath I, Hendrychová D, Maity SK, Buitrago D, Lema R, Nait Achour T, Giunta S, Girardot M, Talarek N, et al. Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair. Nature Communications. 14: 5104. PMID 37607906 DOI: 10.1038/s41467-023-40843-4  0.558
2023 Lin X, Nithun RV, Samanta R, Harel O, Jbara M. Enabling Peptide Ligation at Aromatic Junction Mimics via Native Chemical Ligation and Palladium-Mediated S-Arylation. Organic Letters. PMID 37318270 DOI: 10.1021/acs.orglett.3c01652  0.372
2023 Harel O, Jbara M. Chemical Synthesis of Bioactive Proteins. Angewandte Chemie (International Ed. in English). PMID 36661212 DOI: 10.1002/anie.202217716  0.782
2022 Harel O, Jbara M. Posttranslational Chemical Mutagenesis Methods to Insert Posttranslational Modifications into Recombinant Proteins. Molecules (Basel, Switzerland). 27. PMID 35889261 DOI: 10.3390/molecules27144389  0.775
2021 Pomplun S, Jbara M, Schissel CK, Wilson Hawken S, Boija A, Li C, Klein I, Pentelute BL. Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription. Acs Central Science. 7: 1408-1418. PMID 34471684 DOI: 10.1021/acscentsci.1c00663  0.762
2021 Jbara M, Pomplun S, Schissel CK, Hawken SW, Boija A, Klein I, Rodriguez J, Buchwald SL, Pentelute BL. Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents. Journal of the American Chemical Society. PMID 34289685 DOI: 10.1021/jacs.1c05666  0.763
2021 Jbara M, Rodriguez J, Dhanjee HH, Loas A, Buchwald SL, Pentelute BL. Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents. Angewandte Chemie (International Ed. in English). PMID 33730425 DOI: 10.1002/anie.202103180  0.754
2021 Pomplun S, Jbara M, Quartararo AJ, Zhang G, Brown JS, Lee YC, Ye X, Hanna S, Pentelute BL. Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein. Acs Central Science. 7: 156-163. PMID 33527085 DOI: 10.1021/acscentsci.0c01309  0.772
2020 Jbara M, Eid E, Brik A. Gold(I)-Mediated Decaging or Cleavage of Propargylated Peptide Bond in Aqueous Conditions for Protein Synthesis and Manipulation. Journal of the American Chemical Society. PMID 32290655 DOI: 10.1021/Jacs.9B13216  0.805
2019 Morgan M, Jbara M, Brik A, Wolberger C. Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage. Methods in Enzymology. 618: 1-27. PMID 30850047 DOI: 10.1016/Bs.Mie.2019.01.003  0.813
2019 Nune M, Morgan MT, Connell Z, McCullough L, Jbara M, Sun H, Brik A, Formosa T, Wolberger C. FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics. Elife. 8. PMID 30681413 DOI: 10.7554/Elife.40988  0.783
2019 Jbara M, Maity SK, Brik A. Examining Several Strategies for the Chemical Synthesis of Phosphorylated Histone H3 Reveals the Effectiveness of the Convergent Approach European Journal of Organic Chemistry. 2020: 3128-3132. DOI: 10.1002/Ejoc.201900257  0.633
2018 Jbara M, Laps S, Morgan M, Kamnesky G, Mann G, Wolberger C, Brik A. Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins. Nature Communications. 9: 3154. PMID 30089783 DOI: 10.1038/S41467-018-05628-0  0.839
2018 Jbara M, Eid E, Brik A. Palladium mediated deallylation in fully aqueous conditions for native chemical ligation at aspartic and glutamic acid sites. Organic & Biomolecular Chemistry. PMID 29766191 DOI: 10.1039/C8Ob00890F  0.783
2018 Jbara M, Sun H, Kamnesky G, Brik A. Chemical chromatin ubiquitylation. Current Opinion in Chemical Biology. 45: 18-26. PMID 29459258 DOI: 10.1016/J.Cbpa.2018.02.001  0.817
2018 Nune M, Morgan MT, Connell Z, McCullough L, Jbara M, Sun H, Brik A, Formosa T, Wolberger C. Author response: FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics Elife. DOI: 10.7554/Elife.40988.022  0.53
2017 Maity SK, Jbara M, Mann G, Kamnesky G, Brik A. Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes. Nature Protocols. 12: 2293-2322. PMID 28981125 DOI: 10.1038/Nprot.2017.049  0.823
2017 Jbara M, Guttmann-Raviv N, Maity SK, Ayoub N, Brik A. Total chemical synthesis of methylated analogues of histone 3 revealed KDM4D as a potential regulator of H3K79me3. Bioorganic & Medicinal Chemistry. PMID 28434780 DOI: 10.1016/J.Bmc.2017.04.015  0.791
2017 Brik A, Maity SK, Jbara M. Palladium in Chemical Protein Synthesis and Modifications. Angewandte Chemie (International Ed. in English). PMID 28383786 DOI: 10.1002/Anie.201702370  0.825
2017 Jbara M, Maity SK, Brik A. Palladium in der chemischen Synthese und Modifizierung von Proteinen Angewandte Chemie. 129: 10780-10792. DOI: 10.1002/Ange.201702370  0.7
2016 Jbara M, Laps S, Maity SK, Brik A. Palladium-Assisted Cleavage of Peptides and Proteins Containing a Backbone with Thiazolidine Linkage. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27550063 DOI: 10.1002/Chem.201603676  0.818
2016 Maity SK, Mann G, Jbara M, Laps S, Kamnesky G, Brik A. Palladium-Assisted Removal of a Solubilizing Tag from a Cys Side Chain To Facilitate Peptide and Protein Synthesis. Organic Letters. PMID 27268382 DOI: 10.1021/Acs.Orglett.6B01442  0.827
2016 Maity SK, Jbara M, Laps S, Brik A. Efficient Palladium-Assisted One-Pot Deprotection of (Acetamidomethyl)Cysteine Following Native Chemical Ligation and/or Desulfurization To Expedite Chemical Protein Synthesis. Angewandte Chemie (International Ed. in English). PMID 27126503 DOI: 10.1002/Anie.201603169  0.831
2016 Bondalapati S, Jbara M, Brik A. Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins. Nature Chemistry. 8: 407-18. PMID 27102674 DOI: 10.1038/Nchem.2476  0.832
2016 Jbara M, Maity SK, Seenaiah M, Brik A. Palladium Mediated Rapid Deprotection of N-Terminal Cysteine under Native Chemical Ligation Conditions for the Efficient Preparation of Synthetically Challenging Proteins. Journal of the American Chemical Society. 138: 5069-75. PMID 27023072 DOI: 10.1021/Jacs.5B13580  0.825
2016 Jbara M, Maity SK, Morgan M, Wolberger C, Brik A. Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module. Angewandte Chemie (International Ed. in English). PMID 26960207 DOI: 10.1002/Anie.201600638  0.806
2016 Maity SK, Jbara M, Brik A. Chemical and semisynthesis of modified histones. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 26778211 DOI: 10.1002/Psc.2848  0.818
2016 Bondalapati S, Jbara M, Brik A. Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins Nature Chemistry. 8: 407-418. DOI: 10.1038/nchem.2476  0.463
2015 Seenaiah M, Jbara M, Mali SM, Brik A. Convergent versus sequential protein synthesis: the case of ubiquitinated and glycosylated H2B. Angewandte Chemie (International Ed. in English). 54: 12374-8. PMID 26079184 DOI: 10.1002/Anie.201503309  0.831
2015 Kravtsova-Ivantsiv Y, Shomer I, Cohen-Kaplan V, Snijder B, Superti-Furga G, Gonen H, Sommer T, Ziv T, Admon A, Naroditsky I, Jbara M, Brik A, Pikarsky E, Kwon YT, Doweck I, et al. KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth. Cell. 161: 333-47. PMID 25860612 DOI: 10.1016/J.Cell.2015.03.001  0.754
2015 Seenaiah M, Jbara M, Mali SM, Brik A. Convergent Versus Sequential Protein Synthesis: The Case of Ubiquitinated and Glycosylated H2B Angewandte Chemie - International Edition. 54: 12374-12378. DOI: 10.1002/anie.201503309  0.688
2014 Jbara M, Seenaiah M, Brik A. Solid phase chemical ligation employing a rink amide linker for the synthesis of histone H2B protein Chemical Communications. 50: 12534-12537. PMID 25196573 DOI: 10.1039/C4Cc06499B  0.818
2013 Haj-Yahya N, Haj-Yahya M, Castañeda CA, Spasser L, Hemantha HP, Jbara M, Penner M, Ciechanover A, Fushman D, Brik A. Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins. Angewandte Chemie (International Ed. in English). 52: 11149-53. PMID 24006204 DOI: 10.1002/Anie.201306118  0.794
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