Joachim Herz, MD - Publications

Affiliations: 
Molecular Genetics University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
cholesterol metabolism, Alzheimer's

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Durakoglugil MS, Wasser CR, Wong CH, Pohlkamp T, Xian X, Lane-Donovan C, Fritschle K, Naestle L, Herz J. Reelin regulates neuronal excitability through STriatal Enriched Protein Tyrosine phosphatase (STEP) and Calcium Permeable AMPARs in an NMDAR-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34290083 DOI: 10.1523/JNEUROSCI.0388-21.2021  0.338
2021 Kim JW, Herz J, Kavalali ET, Monteggia LM. A key requirement for synaptic Reelin signaling in ketamine-mediated behavioral and synaptic action. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33975959 DOI: 10.1073/pnas.2103079118  0.301
2020 Kucharava K, Brand Y, Albano G, Sekulic-Jablanovic M, Glutz A, Xian X, Herz J, Bodmer D, Fuster DG, Petkovic V. Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific Reports. 10: 3609. PMID 32107410 DOI: 10.1038/S41598-020-60262-5  0.377
2020 Hamad MIK, Jbara A, Rabaya O, Petrova P, Daoud S, Melliti N, Meseke M, Lutz D, Petrasch-Parwez E, Schwitalla JC, Mark MD, Herlitze S, Reiss G, Herz J, Förster E. Reelin signaling modulates GABA receptor function in the neocortex. Journal of Neurochemistry. PMID 32083308 DOI: 10.1111/Jnc.14990  0.336
2019 Pahle J, Muhia M, Wagener RJ, Tippmann A, Bock HH, Graw J, Herz J, Staiger JF, Drakew A, Kneussel M, Rune GM, Frotscher M, Brunne B. Selective Inactivation of Reelin in Inhibitory Interneurons Leads to Subtle Changes in the Dentate Gyrus But Leaves Cortical Layering and Behavior Unaffected. Cerebral Cortex (New York, N.Y. : 1991). PMID 31667489 DOI: 10.1093/Cercor/Bhz196  0.341
2019 Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, Muglia LJ, Bu G. Correction: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System. Plos Biology. 17: e3000310. PMID 31163031 DOI: 10.1371/Journal.Pbio.3000310  0.379
2018 Xian X, Pohlkamp T, Durakoglugil MS, Wong CH, Beck JK, Lane-Donovan C, Plattner F, Herz J. Reversal of ApoE4 induced recycling block as a novel prevention approach for Alzheimer's disease. Elife. 7. PMID 30375977 DOI: 10.7554/Elife.40048  0.383
2018 Ma Q, Zhao Z, Sagare AP, Wu Y, Wang M, Owens NC, Verghese PB, Herz J, Holtzman DM, Zlokovic BV. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism. Molecular Neurodegeneration. 13: 57. PMID 30340601 DOI: 10.1186/S13024-018-0286-0  0.304
2018 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, et al. Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. Plos One. 13: e0204126. PMID 30235284 DOI: 10.1371/Journal.Pone.0204126  0.323
2018 Hamlin AN, Chinnarasu S, Ding Y, Xian X, Herz J, Jaeschke A, Hui DY. Low density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. The Journal of Biological Chemistry. PMID 29752404 DOI: 10.1074/Jbc.Ra118.001952  0.379
2018 Jaoude AA, Badiqué L, Mlih M, Awan S, Guo S, Lemle A, Abboud C, Foppolo S, Host L, Terrand J, Justiniano H, Herz J, Matz RL, Boucher P. Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation. Scientific Reports. 8: 4501. PMID 29540796 DOI: 10.1038/S41598-018-22819-3  0.382
2018 Sacharidou A, Chambliss KL, Ulrich V, Salmon JE, Shen YM, Herz J, Hui DY, Terada LS, Shaul PW, Mineo C. Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium. Blood. PMID 29500169 DOI: 10.1182/Blood-2017-11-814681  0.32
2017 Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. Elife. 6. PMID 29144234 DOI: 10.7554/Elife.29292  0.484
2017 Evers BM, Rodriguez-Navas C, Tesla RJ, Prange-Kiel J, Wasser CR, Yoo KS, McDonald J, Cenik B, Ravenscroft TA, Plattner F, Rademakers R, Yu G, White CL, Herz J. Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency. Cell Reports. 20: 2565-2574. PMID 28903038 DOI: 10.1016/J.Celrep.2017.08.056  0.375
2017 PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, et al. A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease. Journal of Immunology (Baltimore, Md. : 1950). 198: 3775-3789. PMID 28483986 DOI: 10.4049/Jimmunol.1700373  0.617
2017 van de Sluis B, Wijers M, Herz J. News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1. Current Opinion in Lipidology. PMID 28301372 DOI: 10.1097/Mol.0000000000000411  0.41
2017 Pohlkamp T, Wasser CR, Herz J. Functional Roles of the Interaction of APP and Lipoprotein Receptors. Frontiers in Molecular Neuroscience. 10: 54. PMID 28298885 DOI: 10.3389/Fnmol.2017.00054  0.492
2017 Lane-Donovan C, Herz J. The ApoE receptors Vldlr and Apoer2 in Central Nervous System Function and Disease. Journal of Lipid Research. PMID 28292942 DOI: 10.1194/Jlr.R075507  0.497
2017 Lane-Donovan C, Herz J. ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. Trends in Endocrinology and Metabolism: Tem. PMID 28057414 DOI: 10.1016/J.Tem.2016.12.001  0.343
2016 Wasser CR, Herz J. Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses. The Journal of Biological Chemistry. PMID 27994051 DOI: 10.1074/Jbc.R116.766782  0.345
2016 Pohlkamp T, Xiao L, Sultana R, Bepari A, Bock HH, Henkemeyer M, Herz J. Ephrin Bs and canonical Reelin signalling. Nature. 539: E4-E6. PMID 27882975 DOI: 10.1038/Nature20129  0.352
2016 Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, ... ... Herz J, et al. Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells. Nature Communications. 7: 13516. PMID 27869117 DOI: 10.1038/Ncomms13516  0.391
2016 Strecker P, Ludewig S, Rust M, Mundinger TA, Görlich A, Krächan EG, Mehrfeld C, Herz J, Korte M, Guénette SY, Kins S. FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation. Scientific Reports. 6: 25652. PMID 27734846 DOI: 10.1038/Srep25652  0.322
2016 Lane-Donovan C, Wong WM, Durakoglugil MS, Wasser CR, Jiang S, Xian X, Herz J. Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10141-50. PMID 27683909 DOI: 10.1523/Jneurosci.1054-16.2016  0.393
2016 Beer AG, Zenzmaier C, Schreinlechner M, Haas J, Dietrich MF, Herz J, Marschang P. Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this large LDL receptor family member. Oncotarget. PMID 27626682 DOI: 10.18632/Oncotarget.11897  0.403
2016 Nicholson AM, Finch NA, Almeida M, Perkerson RB, van Blitterswijk M, Wojtas A, Cenik B, Rotondo S, Inskeep V, Almasy L, Dyer T, Peralta J, Jun G, Wood AR, Frayling TM, ... ... Herz J, et al. Prosaposin is a regulator of progranulin levels and oligomerization. Nature Communications. 7: 11992. PMID 27356620 DOI: 10.1038/Ncomms11992  0.325
2016 Ding Y, Xian X, Holland WL, Tsai S, Herz J. Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis. Ebiomedicine. 7: 135-145. PMID 27322467 DOI: 10.1016/J.Ebiom.2016.04.002  0.387
2016 Ding Y, Huang L, Xian X, Yuhanna IS, Wasser CR, Frotscher M, Mineo C, Shaul PW, Herz J. Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation. Science Signaling. 9: ra29. PMID 26980442 DOI: 10.1126/Scisignal.Aad5578  0.411
2016 Wasser CR, Herz J. Splicing therapeutics for Alzheimer's disease. Embo Molecular Medicine. PMID 26902203 DOI: 10.15252/Emmm.201506067  0.325
2016 Lane-Donovan C, Herz J. High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice. Plos One. 11: e0148099. PMID 26828652 DOI: 10.1371/Journal.Pone.0148099  0.311
2016 El Asmar Z, Terrand J, Jenty M, Host L, Mlih M, Zerr A, Justiniano H, Matz RL, Boudier C, Scholler E, Garnier JM, Bertaccini D, Thierse D, Schaeffer C, Van Dorsselaer A, ... Herz J, et al. Convergent signaling pathways controlled by LRP1 cytoplasmic and extracellular domains limit cellular cholesterol accumulation. The Journal of Biological Chemistry. PMID 26792864 DOI: 10.1016/J.Atherosclerosis.2016.07.085  0.434
2015 Ulrich V, Gelber SE, Vukelic M, Sacharidou A, Herz J, Urbanus RT, de Groot PG, Natale DR, Harihara A, Redecha P, Abrahams VM, Shaul PW, Salmon JE, Mineo C. ApoE Receptor 2 mediates trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26474194 DOI: 10.1002/Art.39453  0.346
2015 Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M, Dell'Accio F. Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo. Annals of the Rheumatic Diseases. PMID 26290588 DOI: 10.1136/Annrheumdis-2015-207316  0.419
2015 Lane-Donovan C, Philips GT, Wasser CR, Durakoglugil MS, Masiulis I, Upadhaya A, Pohlkamp T, Coskun C, Kotti T, Steller L, Hammer RE, Frotscher M, Bock HH, Herz J. Reelin protects against amyloid β toxicity in vivo. Science Signaling. 8: ra67. PMID 26152694 DOI: 10.1126/Scisignal.Aaa6674  0.791
2015 Suh J, Moncaster JA, Wang L, Hafeez I, Herz J, Tanzi RE, Goldstein LE, Guénette SY. FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2628-39. PMID 25757569 DOI: 10.1096/Fj.14-261453  0.322
2015 Pohlkamp T, Durakoglugil M, Lane-Donovan C, Xian X, Johnson EB, Hammer RE, Herz J. Lrp4 domains differentially regulate limb/brain development and synaptic plasticity. Plos One. 10: e0116701. PMID 25688974 DOI: 10.1371/Journal.Pone.0116701  0.494
2015 Lane-Donovan C, Herz J, VanHook AM. Science Signaling Podcast: 7 July 2015 Science Signaling. 8. DOI: 10.1126/Scisignal.Aac8470  0.313
2015 Boucher P, El Asmar Z, Jenty M, Terrand J, Host L, Matz R, Justiniano H, Zerr A, Herz J, Bruban V. The cytoplasmic and extracellular domains of LRP1 promote a convergent mechanism for feedback control of cholesterol synthesis and export, and protect against intracellular cholesterol accumulation Atherosclerosis. 241: e23. DOI: 10.1016/J.Atherosclerosis.2015.04.092  0.325
2014 Chakraborty S, Li L, Puliyappadamba VT, Guo G, Hatanpaa KJ, Mickey B, Souza RF, Vo P, Herz J, Chen MR, Boothman DA, Pandita TK, Wang DH, Sen GC, Habib AA. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nature Communications. 5: 5811. PMID 25503978 DOI: 10.1038/Ncomms6811  0.335
2014 Wasser CR, Masiulis I, Durakoglugil MS, Lane-Donovan C, Xian X, Beffert U, Agarwala A, Hammer RE, Herz J. Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning. Science Signaling. 7: ra113. PMID 25429077 DOI: 10.1126/Scisignal.2005438  0.747
2014 Nakajima C, Haffner P, Goerke SM, Zurhove K, Adelmann G, Frotscher M, Herz J, Bock HH, May P. The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. Development (Cambridge, England). 141: 4513-25. PMID 25377550 DOI: 10.1242/Jcs.166173  0.444
2014 Sephton CF, Tang AA, Kulkarni A, West J, Brooks M, Stubblefield JJ, Liu Y, Zhang MQ, Green CB, Huber KM, Huang EJ, Herz J, Yu G. Activity-dependent FUS dysregulation disrupts synaptic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: E4769-78. PMID 25324524 DOI: 10.1073/Pnas.1406162111  0.393
2014 Ulrich V, Konaniah ES, Lee WR, Khadka S, Shen YM, Herz J, Salmon JE, Hui DY, Shaul PW, Mineo C. Antiphospholipid antibodies attenuate endothelial repair and promote neointima formation in mice. Journal of the American Heart Association. 3: e001369. PMID 25315347 DOI: 10.1161/Jaha.114.001369  0.373
2014 Ulrich V, Konaniah ES, Herz J, Gerard RD, Jung E, Yuhanna IS, Ahmed M, Hui DY, Mineo C, Shaul PW. Genetic variants of ApoE and ApoER2 differentially modulate endothelial function. Proceedings of the National Academy of Sciences of the United States of America. 111: 13493-8. PMID 25197062 DOI: 10.1073/Pnas.1402106111  0.353
2014 Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/Jem.20140214  0.361
2014 Lane-Donovan C, Philips GT, Herz J. More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration. Neuron. 83: 771-87. PMID 25144875 DOI: 10.1016/J.Neuron.2014.08.005  0.811
2014 Lane-Donovan C, Herz J. Is apolipoprotein e required for cognitive function in humans?: implications for Alzheimer drug development. Jama Neurology. 71: 1213-5. PMID 25110920 DOI: 10.1001/Jamaneurol.2014.2013  0.404
2014 Schorch B, Song S, van Diemen FR, Bock HH, May P, Herz J, Brummelkamp TR, Papatheodorou P, Aktories K. LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins. Proceedings of the National Academy of Sciences of the United States of America. 111: 6431-6. PMID 24737893 DOI: 10.1073/Pnas.1323790111  0.412
2014 Prabhudas M, Bowdish D, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, Means TK, Moestrup SK, Post S, Sawamura T, Silverstein S, Wang XY, El Khoury J. Standardizing scavenger receptor nomenclature. Journal of Immunology (Baltimore, Md. : 1950). 192: 1997-2006. PMID 24563502 DOI: 10.4049/Jimmunol.1490003  0.619
2014 Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M, Tabas I. An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. The Journal of Clinical Investigation. 124: 1296-308. PMID 24509082 DOI: 10.1172/Jci72051  0.351
2014 Gilat-Frenkel M, Boehm-Cagan A, Liraz O, Xian X, Herz J, Michaelson DM. Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo. Current Alzheimer Research. 11: 549-57. PMID 24251389 DOI: 10.2174/1567205010666131119232444  0.467
2014 Wasser CR, Herz J, VanHook AM. Science Signaling podcast: 25 November 2014 Science Signaling. 7. DOI: 10.1126/Scisignal.Aaa1326  0.487
2013 Bal M, Leitz J, Reese AL, Ramirez DM, Durakoglugil M, Herz J, Monteggia LM, Kavalali ET. Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Neuron. 80: 934-46. PMID 24210904 DOI: 10.1016/J.Neuron.2013.08.024  0.304
2013 Choi HY, Liu Y, Tennert C, Sugiura Y, Karakatsani A, Kröger S, Johnson EB, Hammer RE, Lin W, Herz J. APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife. 2: e00220. PMID 23986861 DOI: 10.7554/Elife.00220  0.474
2013 Brunne B, Franco S, Bouché E, Herz J, Howell BW, Pahle J, Müller U, May P, Frotscher M, Bock HH. Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia. 61: 1347-63. PMID 23828756 DOI: 10.1002/Glia.22519  0.346
2013 Nakajima C, Kulik A, Frotscher M, Herz J, Schäfer M, Bock HH, May P. Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes. The Journal of Biological Chemistry. 288: 21909-23. PMID 23760271 DOI: 10.1074/Jbc.M112.444364  0.447
2013 Chen X, Chang J, Deng Q, Xu J, Nguyen TA, Martens LH, Cenik B, Taylor G, Hudson KF, Chung J, Yu K, Yu P, Herz J, Farese RV, Kukar T, et al. Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9202-13. PMID 23699531 DOI: 10.1523/Jneurosci.5336-12.2013  0.362
2013 Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/Jbc.M112.441949  0.346
2013 Bouché E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH. Reelin induces EphB activation. Cell Research. 23: 473-90. PMID 23318582 DOI: 10.1038/Cr.2013.7  0.47
2013 Carlo AS, Gustafsen C, Mastrobuoni G, Nielsen MS, Burgert T, Hartl D, Rohe M, Nykjaer A, Herz J, Heeren J, Kempa S, Petersen CM, Willnow TE. The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 358-70. PMID 23283348 DOI: 10.1523/Jneurosci.2425-12.2013  0.508
2013 Choi HY, Liu Y, Tennert C, Sugiura Y, Karakatsani A, Kröger S, Johnson EB, Hammer RE, Lin W, Herz J. Author response: APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice Elife. DOI: 10.7554/Elife.00220.017  0.304
2012 Sekine K, Kawauchi T, Kubo K, Honda T, Herz J, Hattori M, Kinashi T, Nakajima K. Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1. Neuron. 76: 353-69. PMID 23083738 DOI: 10.1016/J.Neuron.2012.07.020  0.327
2012 Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, ... ... Herz J, et al. The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells. Nature Communications. 3: 1077. PMID 23011131 DOI: 10.1038/Ncomms2087  0.41
2012 Sephton CF, Cenik B, Cenik BK, Herz J, Yu G. TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration. Biological Chemistry. 393: 589-94. PMID 22944662 DOI: 10.1515/Hsz-2012-0115  0.323
2012 Du Y, Yang M, Wei W, Huynh HD, Herz J, Saghatelian A, Wan Y. Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates. Nature Communications. 3: 1008. PMID 22910354 DOI: 10.1038/Ncomms2011  0.395
2012 Cenik B, Sephton CF, Kutluk Cenik B, Herz J, Yu G. Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration. The Journal of Biological Chemistry. 287: 32298-306. PMID 22859297 DOI: 10.1074/Jbc.R112.399170  0.371
2012 Holtzman DM, Herz J, Bu G. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006312. PMID 22393530 DOI: 10.1101/Cshperspect.A006312  0.483
2012 Porntaveetus T, Ohazama A, Choi HY, Herz J, Sharpe PT. Wnt signaling in the murine diastema. European Journal of Orthodontics. 34: 518-24. PMID 21531785 DOI: 10.1093/Ejo/Cjr049  0.374
2011 Trotter JH, Klein M, Jinwal UK, Abisambra JF, Dickey CA, Tharkur J, Masiulis I, Ding J, Locke KG, Rickman CB, Birch DG, Weeber EJ, Herz J. ApoER2 function in the establishment and maintenance of retinal synaptic connectivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14413-23. PMID 21976526 DOI: 10.1523/Jneurosci.3135-11.2011  0.398
2011 Woldt E, Matz RL, Terrand J, Mlih M, Gracia C, Foppolo S, Martin S, Bruban V, Ji J, Velot E, Herz J, Boucher P. Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor. The Journal of Biological Chemistry. 286: 16775-82. PMID 21454706 DOI: 10.1074/Jbc.M110.212878  0.426
2011 Haas J, Beer AG, Widschwendter P, Oberdanner J, Salzmann K, Sarg B, Lindner H, Herz J, Patsch JR, Marschang P. LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE-carrying lipoproteins. Atherosclerosis. 216: 342-7. PMID 21420681 DOI: 10.1016/J.Atherosclerosis.2011.02.030  0.393
2011 Nagajyothi F, Weiss LM, Silver DL, Desruisseaux MS, Scherer PE, Herz J, Tanowitz HB. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. Plos Neglected Tropical Diseases. 5: e953. PMID 21408103 DOI: 10.1371/Journal.Pntd.0000953  0.322
2011 Long H, Bock HH, Lei T, Chai X, Yuan J, Herz J, Frotscher M, Yang Z. Identification of alternatively spliced Dab1 and Fyn isoforms in pig. Bmc Neuroscience. 12: 17. PMID 21294906 DOI: 10.1186/1471-2202-12-17  0.347
2011 Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, Muglia LJ, Bu G. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. Plos Biology. 9: e1000575. PMID 21264353 DOI: 10.1371/Journal.Pbio.1000575  0.409
2011 Ramesh S, Morrell CN, Tarango C, Thomas GD, Yuhanna IS, Girardi G, Herz J, Urbanus RT, de Groot PG, Thorpe PE, Salmon JE, Shaul PW, Mineo C. Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. The Journal of Clinical Investigation. 121: 120-31. PMID 21123944 DOI: 10.1172/Jci39828  0.386
2011 Boucher P, Herz J. Signaling through LRP1: Protection from atherosclerosis and beyond. Biochemical Pharmacology. 81: 1-5. PMID 20920479 DOI: 10.1016/J.Bcp.2010.09.018  0.489
2010 Ohazama A, Porntaveetus T, Ota MS, Herz J, Sharpe PT. Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis. American Journal of Medical Genetics. Part A. 152: 2974-83. PMID 21108386 DOI: 10.1002/Ajmg.A.33372  0.441
2010 Leemhuis J, Bouché E, Frotscher M, Henle F, Hein L, Herz J, Meyer DK, Pichler M, Roth G, Schwan C, Bock HH. Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14759-72. PMID 21048135 DOI: 10.1523/Jneurosci.4036-10.2010  0.425
2010 Dieckmann M, Dietrich MF, Herz J. Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family. Biological Chemistry. 391: 1341-63. PMID 20868222 DOI: 10.1515/Bc.2010.129  0.499
2010 Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH. Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia. 58: 1553-69. PMID 20549747 DOI: 10.1002/Glia.21029  0.33
2010 Chen Y, Durakoglugil MS, Xian X, Herz J. ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling. Proceedings of the National Academy of Sciences of the United States of America. 107: 12011-6. PMID 20547867 DOI: 10.1073/Pnas.0914984107  0.474
2010 Förster E, Bock HH, Herz J, Chai X, Frotscher M, Zhao S. Emerging topics in Reelin function. The European Journal of Neuroscience. 31: 1511-8. PMID 20525064 DOI: 10.1111/J.1460-9568.2010.07222.X  0.408
2010 Dietrich MF, van der Weyden L, Prosser HM, Bradley A, Herz J, Adams DJ. Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo. Plos One. 5: e9960. PMID 20383322 DOI: 10.1371/Journal.Pone.0009960  0.493
2010 Li Y, Pawlik B, Elcioglu N, Aglan M, Kayserili H, Yigit G, Percin F, Goodman F, Nürnberg G, Cenani A, Urquhart J, Chung BD, Ismail S, Amr K, Aslanger AD, ... ... Herz J, et al. LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. American Journal of Human Genetics. 86: 696-706. PMID 20381006 DOI: 10.1016/J.Ajhg.2010.03.004  0.382
2010 Sephton CF, Good SK, Atkin S, Dewey CM, Mayer P, Herz J, Yu G. TDP-43 is a developmentally regulated protein essential for early embryonic development. The Journal of Biological Chemistry. 285: 6826-34. PMID 20040602 DOI: 10.1074/Jbc.M109.061846  0.373
2010 Ohazama A, Blackburn J, Porntaveetus T, Ota MS, Choi HY, Johnson EB, Myers P, Oommen S, Eto K, Kessler JA, Kondo T, Fraser GJ, Streelman JT, Pardiñas UF, Tucker AS, ... ... Herz J, et al. A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition. Proceedings of the National Academy of Sciences of the United States of America. 107: 92-7. PMID 20018657 DOI: 10.1073/Pnas.0907236107  0.366
2010 Jedrychowski MP, Gartner CA, Gygi SP, Zhou L, Herz J, Kandror KV, Pilch PF. Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. The Journal of Biological Chemistry. 285: 104-14. PMID 19864425 DOI: 10.1074/Jbc.M109.040428  0.327
2009 Choi HY, Dieckmann M, Herz J, Niemeier A. Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. Plos One. 4: e7930. PMID 19936252 DOI: 10.1371/Journal.Pone.0007930  0.36
2009 Durakoglugil MS, Chen Y, White CL, Kavalali ET, Herz J. Reelin signaling antagonizes beta-amyloid at the synapse. Proceedings of the National Academy of Sciences of the United States of America. 106: 15938-43. PMID 19805234 DOI: 10.1073/Pnas.0908176106  0.418
2009 Zhou L, Takayama Y, Boucher P, Tallquist MD, Herz J. LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation. Plos One. 4: e6922. PMID 19742316 DOI: 10.1371/Journal.Pone.0006922  0.417
2009 Basford JE, Moore ZW, Zhou L, Herz J, Hui DY. Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1772-8. PMID 19729608 DOI: 10.1161/Atvbaha.109.194357  0.366
2009 Zhou L, Choi HY, Li WP, Xu F, Herz J. LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. Plos One. 4: e6853. PMID 19718435 DOI: 10.1371/Journal.Pone.0006853  0.42
2009 Herz J. Apolipoprotein E receptors in the nervous system. Current Opinion in Lipidology. 20: 190-6. PMID 19433918 DOI: 10.1097/Mol.0B013E32832D3A10  0.482
2009 Herz J, Chen Y, Masiulis I, Zhou L. Expanding functions of lipoprotein receptors. Journal of Lipid Research. 50: S287-92. PMID 19017612 DOI: 10.1194/Jlr.R800077-Jlr200  0.479
2009 Masiulis I, Quill TA, Burk RF, Herz J. Differential functions of the Apoer2 intracellular domain in selenium uptake and cell signaling. Biological Chemistry. 390: 67-73. PMID 19007311 DOI: 10.1515/Bc.2009.011  0.444
2009 Terrand J, Bruban V, Zhou L, Gong W, El Asmar Z, May P, Zurhove K, Haffner P, Philippe C, Woldt E, Matz RL, Gracia C, Metzger D, Auwerx J, Herz J, et al. LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. The Journal of Biological Chemistry. 284: 381-8. PMID 18990694 DOI: 10.1074/Jbc.M806538200  0.423
2009 Tarango C, Ramesh S, Morrell CN, Thomas GD, Girardi G, Salmon J, Yuhanna IS, Herz J, Thorpe P, Shaul P, Mineo C. Antiphospholipid Antibodies Promote Leukocyte-Endothelial Cell Adhesion by Antagonizing Endothelial NO Synthase Via b2GPI and ApoER2. Blood. 114: 3039-3039. DOI: 10.1182/Blood.V114.22.3039.3039  0.382
2009 Herz J. S5-02-06: The role of ApoE and ApoE receptors for synaptic dysfunction in Alzheimer's disease Alzheimer's & Dementia. 5: P168-P169. DOI: 10.1016/J.Jalz.2009.05.582  0.387
2009 Herz J, Durakoglugil M, Chen Y, Masiulis I, Choi H, Dietrich M, Xunde X. The LDL-receptor family—mediators of signal transduction Chemistry and Physics of Lipids. 160: S4. DOI: 10.1016/J.Chemphyslip.2009.06.097  0.449
2008 Ohazama A, Johnson EB, Ota MS, Choi HY, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT. Lrp4 modulates extracellular integration of cell signaling pathways in development. Plos One. 3: e4092. PMID 19116665 DOI: 10.1371/Journal.Pone.0004092  0.375
2008 Zurhove K, Nakajima C, Herz J, Bock HH, May P. Gamma-secretase limits the inflammatory response through the processing of LRP1. Science Signaling. 1: ra15. PMID 19036715 DOI: 10.1126/Scisignal.1164263  0.32
2008 Larouche M, Beffert U, Herz J, Hawkes R. The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. Plos One. 3: e1653. PMID 18301736 DOI: 10.1371/Journal.Pone.0001653  0.739
2008 Akopians AL, Babayan AH, Beffert U, Herz J, Basbaum AI, Phelps PE. Contribution of the Reelin signaling pathways to nociceptive processing. The European Journal of Neuroscience. 27: 523-37. PMID 18279306 DOI: 10.1111/J.1460-9568.2008.06056.X  0.715
2008 Bock HH, Herz J. Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. 15-35. DOI: 10.1007/978-0-387-76761-1_2  0.358
2007 Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, Thomas A, Pfluger PT, Basford JE, Gilham D, Herz J, Tschöp MH, Hui DY. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. The Journal of Clinical Investigation. 117: 3271-82. PMID 17948131 DOI: 10.1172/Jci31929  0.353
2007 Liu Q, Zerbinatti CV, Zhang J, Hoe HS, Wang B, Cole SL, Herz J, Muglia L, Bu G. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron. 56: 66-78. PMID 17920016 DOI: 10.1016/J.Neuron.2007.08.008  0.442
2007 Boucher P, Li WP, Matz RL, Takayama Y, Auwerx J, Anderson RG, Herz J. LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. Plos One. 2: e448. PMID 17505534 DOI: 10.1371/Journal.Pone.0000448  0.415
2007 Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Herz J, Clark GD, D'Arcangelo G. The Pafah1b complex interacts with the reelin receptor VLDLR. Plos One. 2: e252. PMID 17330141 DOI: 10.1371/Journal.Pone.0000252  0.752
2007 Bock HH, Herz J, May P. Conditional animal models for the study of lipid metabolism and lipid disorders Handbook of Experimental Pharmacology. 178: 407-439. PMID 17203665 DOI: 10.1007/978-3-540-35109-2_17  0.35
2007 Jones C, Garuti R, Michaely P, Li WP, Maeda N, Cohen JC, Herz J, Hobbs HH. Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. The Journal of Clinical Investigation. 117: 165-74. PMID 17200716 DOI: 10.1172/Jci29415  0.625
2007 Lukowski R, Bernhard D, Weinmeister P, Feil S, Gotthardt M, Herz J, Massberg S, Hofmann F, Feil R. Vascular remodelling in the absence and presence of cGKI Bmc Pharmacology. 7: 1-1. DOI: 10.1186/1471-2210-7-S1-S41  0.368
2006 Beffert U, Nematollah Farsian F, Masiulis I, Hammer RE, Yoon SO, Giehl KM, Herz J. ApoE receptor 2 controls neuronal survival in the adult brain. Current Biology : Cb. 16: 2446-52. PMID 17174920 DOI: 10.1016/J.Cub.2006.10.029  0.737
2006 Herz J, Chen Y. Reelin, lipoprotein receptors and synaptic plasticity. Nature Reviews. Neuroscience. 7: 850-9. PMID 17053810 DOI: 10.1038/Nrn2009  0.509
2006 Hu L, Boesten LSM, May P, Herz J, Bovenschen N, Huisman MV, Berbée JFP, Havekes LM, Van Vlijmen BJM, Tamsma JT. Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in apoE/LDLR double knockout mice Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2710-2715. PMID 17038633 DOI: 10.1161/01.Atv.0000249641.96896.E6  0.474
2006 Johnson EB, Steffen DJ, Lynch KW, Herz J. Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease. Genomics. 88: 600-9. PMID 16963222 DOI: 10.1016/J.Ygeno.2006.08.005  0.334
2006 Herz J. The switch on the RAPper's necklace... Molecular Cell. 23: 451-5. PMID 16916634 DOI: 10.1016/J.Molcel.2006.07.026  0.336
2006 Li X, Herz J, Monard D. Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1. Journal of Cellular Biochemistry. 99: 936-51. PMID 16741952 DOI: 10.1002/Jcb.20881  0.436
2006 Cao C, Lawrence DA, Li Y, Von Arnim CA, Herz J, Su EJ, Makarova A, Hyman BT, Strickland DK, Zhang L. Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. The Embo Journal. 25: 1860-70. PMID 16601674 DOI: 10.1038/Sj.Emboj.7601082  0.37
2006 Beffert U, Durudas A, Weeber EJ, Stolt PC, Giehl KM, Sweatt JD, Hammer RE, Herz J. Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2041-52. PMID 16481437 DOI: 10.1523/Jneurosci.4566-05.2006  0.768
2006 Guénette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J. Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. The Embo Journal. 25: 420-31. PMID 16407979 DOI: 10.1038/Sj.Emboj.7600926  0.302
2006 Hu L, Boesten L, May P, Herz J, Bovenschen N, Huisman M, Berbee J, Havekes L, Van Vlijmen B, Tamsma J. We-W43:6 Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis Atherosclerosis Supplements. 7: 331. DOI: 10.1016/S1567-5688(06)81321-8  0.451
2006 Hu L, Tamsma JT, Boesten LS, May P, Herz J, Bovenschen N, Huisman MV, Berbee JF, Havekes LM, van Vlijmen BJ. Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in mice Vascular Pharmacology. 45: e99. DOI: 10.1016/J.Vph.2006.08.276  0.47
2005 Johnson EB, Hammer RE, Herz J. Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Human Molecular Genetics. 14: 3523-38. PMID 16207730 DOI: 10.1093/Hmg/Ddi381  0.431
2005 Garuti R, Jones C, Li WP, Michaely P, Herz J, Gerard RD, Cohen JC, Hobbs HH. The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits. The Journal of Biological Chemistry. 280: 40996-1004. PMID 16179341 DOI: 10.1074/Jbc.M509394200  0.635
2005 May P, Herz J, Bock HH. Molecular mechanisms of lipoprotein receptor signalling Cellular and Molecular Life Sciences. 62: 2325-2338. PMID 16158188 DOI: 10.1007/S00018-005-5231-Z  0.505
2005 Chen Y, Beffert U, Ertunc M, Tang TS, Kavalali ET, Bezprozvanny I, Herz J. Reelin modulates NMDA receptor activity in cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8209-16. PMID 16148228 DOI: 10.1523/Jneurosci.1951-05.2005  0.757
2005 Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, et al. Suppression of aging in mice by the hormone Klotho. Science (New York, N.Y.). 309: 1829-33. PMID 16123266 DOI: 10.1126/Science.1112766  0.339
2005 Beffert U, Weeber EJ, Durudas A, Qiu S, Masiulis I, Sweatt JD, Li WP, Adelmann G, Frotscher M, Hammer RE, Herz J. Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron. 47: 567-79. PMID 16102539 DOI: 10.1016/J.Neuron.2005.07.007  0.755
2005 Takayama Y, May P, Anderson RG, Herz J. Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta). The Journal of Biological Chemistry. 280: 18504-10. PMID 15753096 DOI: 10.1074/Jbc.M410265200  0.481
2005 Stolt PC, Chen Y, Liu P, Bock HH, Blacklow SC, Herz J. Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction. The Journal of Biological Chemistry. 280: 9671-7. PMID 15632144 DOI: 10.1074/Jbc.M413356200  0.419
2005 Petit-Turcotte C, Aumont N, Beffert U, Dea D, Herz J, Poirier J. The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity. Neurobiology of Aging. 26: 195-206. PMID 15582748 DOI: 10.1016/J.Neurobiolaging.2004.04.007  0.791
2005 Lukowski R, Weinmeister P, Vogl A, Feil S, Gotthardt M, Herz J, Massberg S, Hofmann F, Feil R. Function of smooth muscle cGMP-dependent protein kinase type I in a mouse model of restenosis Bmc Pharmacology. 5: 32. DOI: 10.1186/1471-2210-5-S1-P32  0.333
2004 May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Molecular and Cellular Biology. 24: 8872-83. PMID 15456862 DOI: 10.1128/Mcb.24.20.8872-8883.2004  0.757
2004 Bock HH, Jossin Y, May P, Bergner O, Herz J. Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. The Journal of Biological Chemistry. 279: 33471-9. PMID 15175346 DOI: 10.1074/Jbc.M401770200  0.485
2004 Marschang P, Brich J, Weeber EJ, Sweatt JD, Shelton JM, Richardson JA, Hammer RE, Herz J. Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Molecular and Cellular Biology. 24: 3782-93. PMID 15082773 DOI: 10.1128/Mcb.24.9.3782-3793.2004  0.498
2004 Herz J, Hui DY. Lipoprotein receptors in the vascular wall. Current Opinion in Lipidology. 15: 175-81. PMID 15017360 DOI: 10.1097/00041433-200404000-00010  0.408
2004 Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1897-906. PMID 14985430 DOI: 10.1523/Jneurosci.4084-03.2004  0.706
2004 Espirito Santo SM, Pires NM, Boesten LS, Gerritsen G, Bovenschen N, van Dijk KW, Jukema JW, Princen HM, Bensadoun A, Li WP, Herz J, Havekes LM, van Vlijmen BJ. Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol. Blood. 103: 3777-82. PMID 14739216 DOI: 10.1182/Blood-2003-11-4051  0.419
2004 Strasser V, Fasching D, Hauser C, Mayer H, Bock HH, Hiesberger T, Herz J, Weeber EJ, Sweatt JD, Pramatarova A, Howell B, Schneider WJ, Nimpf J. Receptor clustering is involved in Reelin signaling. Molecular and Cellular Biology. 24: 1378-86. PMID 14729980 DOI: 10.1128/Mcb.24.3.1378-1386.2004  0.452
2004 Jossin Y, Ignatova N, Hiesberger T, Herz J, Lambert de Rouvroit C, Goffinet AM. The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 514-21. PMID 14724251 DOI: 10.1523/Jneurosci.3408-03.2004  0.486
2004 Vergés M, Bensadoun A, Herz J, Belcher JD, Havel RJ. Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 279: 9030-6. PMID 14701798 DOI: 10.1074/Jbc.M312908200  0.413
2004 Beffert U, Stolt PC, Herz J. Functions of lipoprotein receptors in neurons. Journal of Lipid Research. 45: 403-9. PMID 14657206 DOI: 10.1194/Jlr.R300017-Jlr200  0.768
2004 May P, Herz J. LDL receptor-related proteins in neurodevelopment. Traffic (Copenhagen, Denmark). 4: 291-301. PMID 12713657 DOI: 10.1034/J.1600-0854.2003.00086_4_5.X  0.506
2004 Marschang P, Brich J, Weeber E, Sweatt J, Shelton J, Richardson J, Hammer R, Herz J. W13.317 Characterization of LRP1b, a large member of the LDL receptor family and putative tumor suppressor, in the mouse Atherosclerosis Supplements. 5: 73. DOI: 10.1016/S1567-5688(04)90316-4  0.37
2003 Herz J. LRP: a bright beacon at the blood-brain barrier. The Journal of Clinical Investigation. 112: 1483-5. PMID 14617749 DOI: 10.1172/Jci20337  0.438
2003 Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nature Genetics. 35: 270-6. PMID 14578885 DOI: 10.1038/Ng1257  0.714
2003 Hartfuss E, Förster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Götz M. Reelin signaling directly affects radial glia morphology and biochemical maturation. Development (Cambridge, England). 130: 4597-609. PMID 12925587 DOI: 10.1242/Dev.00654  0.382
2003 Bock HH, Jossin Y, Liu P, Förster E, May P, Goffinet AM, Herz J. Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. The Journal of Biological Chemistry. 278: 38772-9. PMID 12882964 DOI: 10.1074/Jbc.M306416200  0.455
2003 May P, Bock HH, Nimpf J, Herz J. Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase. The Journal of Biological Chemistry. 278: 37386-92. PMID 12871934 DOI: 10.1074/Jbc.M305858200  0.464
2003 Jones C, Hammer RE, Li WP, Cohen JC, Hobbs HH, Herz J. Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. The Journal of Biological Chemistry. 278: 29024-30. PMID 12746448 DOI: 10.1074/Jbc.M304855200  0.648
2003 Stolt PC, Jeon H, Song HK, Herz J, Eck MJ, Blacklow SC. Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes. Structure (London, England : 1993). 11: 569-79. PMID 12737822 DOI: 10.1016/S0969-2126(03)00068-6  0.36
2003 Andersen OM, Yeung CH, Vorum H, Wellner M, Andreassen TK, Erdmann B, Mueller EC, Herz J, Otto A, Cooper TG, Willnow TE. Essential role of the apolipoprotein E receptor-2 in sperm development. The Journal of Biological Chemistry. 278: 23989-95. PMID 12695510 DOI: 10.1074/Jbc.M302157200  0.498
2003 Boucher P, Gotthardt M, Li WP, Anderson RG, Herz J. LRP: role in vascular wall integrity and protection from atherosclerosis. Science (New York, N.Y.). 300: 329-32. PMID 12690199 DOI: 10.1126/Science.1082095  0.418
2003 Weiss KH, Johanssen C, Tielsch A, Herz J, Deller T, Frotscher M, Förster E. Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice. The Journal of Comparative Neurology. 460: 56-65. PMID 12687696 DOI: 10.1002/Cne.10644  0.474
2003 May P, Bock HH, Herz J. Integration of endocytosis and signal transduction by lipoprotein receptors. Science's Stke : Signal Transduction Knowledge Environment. 2003: PE12. PMID 12671190 DOI: 10.1126/Stke.2003.176.Pe12  0.449
2003 Roehrich ME, Mooser V, Lenain V, Herz J, Nimpf J, Azhar S, Bideau M, Capponi A, Nicod P, Haefliger JA, Waeber G. Insulin-secreting beta-cell dysfunction induced by human lipoproteins. The Journal of Biological Chemistry. 278: 18368-75. PMID 12594227 DOI: 10.1074/Jbc.M300102200  0.39
2003 Herz J, Marschang P. Coaxing the LDL receptor family into the fold. Cell. 112: 289-92. PMID 12581519 DOI: 10.1016/S0092-8674(03)00073-4  0.445
2003 Bock HH, Herz J. Reelin activates SRC family tyrosine kinases in neurons. Current Biology : Cb. 13: 18-26. PMID 12526740 DOI: 10.1016/S0960-9822(02)01403-3  0.453
2003 Marschang P, Herz J. Mouse models as tools for dissecting disorders of lipoprotein metabolism. Seminars in Cell & Developmental Biology. 14: 25-35. PMID 12524004 DOI: 10.1016/S1084-9521(02)00169-6  0.32
2003 Bovenschen N, Herz J, Grimbergen JM, Lenting PJ, Havekes LM, Mertens K, van Vlijmen BJ. Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency. Blood. 101: 3933-9. PMID 12522008 DOI: 10.1182/Blood-2002-07-2081  0.384
2003 Brich J, Shie F, Howell BW, Li R, Tus K, Wakeland EK, Jin L, Mumby M, Churchill G, Herz J, Cooper JA. Genetic Modulation of Tau Phosphorylation in the Mouse The Journal of Neuroscience. 23: 187-192. DOI: 10.1523/Jneurosci.23-01-00187.2003  0.375
2003 Santo SE, Pires N, Gerritsen G, Bovenschen N, Dijk KWv, Princen H, Bensadoun A, Herz J, Vlijmen BV, Havekes L. 3P-0740 Low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol Atherosclerosis Supplements. 4: 224. DOI: 10.1016/S1567-5688(03)90958-5  0.454
2002 Beffert U, Morfini G, Bock HH, Reyna H, Brady ST, Herz J. Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. The Journal of Biological Chemistry. 277: 49958-64. PMID 12376533 DOI: 10.1074/Jbc.M209205200  0.724
2002 Weeber EJ, Beffert U, Jones C, Christian JM, Forster E, Sweatt JD, Herz J. Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. The Journal of Biological Chemistry. 277: 39944-52. PMID 12167620 DOI: 10.1074/Jbc.M205147200  0.766
2002 Drakew A, Deller T, Heimrich B, Gebhardt C, Del Turco D, Tielsch A, Förster E, Herz J, Frotscher M. Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice. Experimental Neurology. 176: 12-24. PMID 12093079 DOI: 10.1006/Exnr.2002.7918  0.396
2002 Gebhardt C, Del Turco D, Drakew A, Tielsch A, Herz J, Frotscher M, Deller T. Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice. The Journal of Comparative Neurology. 445: 278-92. PMID 11920707 DOI: 10.1002/Cne.10172  0.379
2002 May P, Reddy YK, Herz J. Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. The Journal of Biological Chemistry. 277: 18736-43. PMID 11907044 DOI: 10.1074/Jbc.M201979200  0.441
2002 Boucher P, Liu P, Gotthardt M, Hiesberger T, Anderson RG, Herz J. Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae. The Journal of Biological Chemistry. 277: 15507-13. PMID 11854295 DOI: 10.1074/Jbc.M200428200  0.489
2001 Herz J, Bock HH. Lipoprotein receptors in the nervous system. Annual Review of Biochemistry. 71: 405-34. PMID 12045102 DOI: 10.1146/Annurev.Biochem.71.110601.135342  0.465
2001 Honarpour N, Tabuchi K, Stark JM, Hammer RE, Südhof TC, Parada LF, Wang X, Richardson JA, Herz J. Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1. Neuroscience. 106: 263-74. PMID 11566499 DOI: 10.1016/S0306-4522(01)00275-5  0.453
2001 Herz J, Strickland DK. LRP: a multifunctional scavenger and signaling receptor. The Journal of Clinical Investigation. 108: 779-84. PMID 11560943 DOI: 10.1172/Jci13992  0.444
2001 Honarpour N, Gilbert SL, Lahn BT, Wang X, Herz J. Apaf-1 deficiency and neural tube closure defects are found in fog mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 9683-7. PMID 11504943 DOI: 10.1073/Pnas.171283198  0.434
2001 Herz J. Deconstructing the LDL receptor--a rhapsody in pieces. Nature Structural Biology. 8: 476-8. PMID 11373607 DOI: 10.1038/88519  0.445
2001 Herz J. The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron. 29: 571-81. PMID 11301018 DOI: 10.1016/S0896-6273(01)00234-3  0.409
2001 Herz J. Lipoprotein receptors: beacons to neurons? Trends in Neurosciences. 24: 193-5. PMID 11249989 DOI: 10.1016/S0166-2236(00)01768-9  0.518
2001 Howell BW, Herz J. The LDL receptor gene family: Signaling functions during development Current Opinion in Neurobiology. 11: 74-81. PMID 11179875 DOI: 10.1016/S0959-4388(00)00176-8  0.457
2000 Herz J, Beffert U. Apolipoprotein E receptors: linking brain development and Alzheimer's disease. Nature Reviews. Neuroscience. 1: 51-8. PMID 11252768 DOI: 10.1038/35036221  0.723
2000 Stockinger W, Brandes C, Fasching D, Hermann M, Gotthardt M, Herz J, Schneider WJ, Nimpf J. The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2. The Journal of Biological Chemistry. 275: 25625-32. PMID 10827199 DOI: 10.1074/Jbc.M004119200  0.513
2000 Gotthardt M, Trommsdorff M, Nevitt MF, Shelton J, Richardson JA, Stockinger W, Nimpf J, Herz J. Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. The Journal of Biological Chemistry. 275: 25616-24. PMID 10827173 DOI: 10.1074/Jbc.M000955200  0.535
2000 Herz J, Gotthardt M, Willnow TE. Cellular signalling by lipoprotein receptors. Current Opinion in Lipidology. 11: 161-6. PMID 10787178 DOI: 10.1097/00041433-200004000-00009  0.5
2000 Marshall P, Rohlmann A, Nussenzweig V, Herz J, Sinnis P. Plasmodium sporozoites invade cells with targeted deletions in the LDL receptor related protein Molecular and Biochemical Parasitology. 106: 293-298. PMID 10699258 DOI: 10.1016/S0166-6851(99)00210-8  0.441
2000 Honarpour N, Du C, Richardson JA, Hammer RE, Wang X, Herz J. Adult Apaf-1-deficient mice exhibit male infertility. Developmental Biology. 218: 248-58. PMID 10656767 DOI: 10.1006/Dbio.1999.9585  0.444
2000 Willnow TE, Nykjaer A, Herz J. Lipoprotein receptors: new roles for ancient proteins. Nature Cell Biology. 1: E157-62. PMID 10559979 DOI: 10.1038/14109  0.481
2000 Herz J. Potential roles of the LDL receptor gene family in Alzheimer disease Neurobiology of Aging. 21: 5. DOI: 10.1016/S0197-4580(00)82696-2  0.4
2000 Herz J. Complex genetic functions of the LDL receptor gene family Atherosclerosis. 151: 240. DOI: 10.1016/S0021-9150(00)81089-8  0.381
1999 van Vlijmen BJ, Rohlmann A, Page ST, Bensadoun A, Bos IS, van Berkel TJ, Havekes LM, Herz J. An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins. The Journal of Biological Chemistry. 274: 35219-26. PMID 10575007 DOI: 10.1074/Jbc.274.49.35219  0.457
1999 Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, Cooper JA, Herz J. Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron. 24: 481-9. PMID 10571241 DOI: 10.1016/S0896-6273(00)80861-2  0.45
1999 Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W, Nimpf J, Hammer RE, Richardson JA, Herz J. Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 97: 689-701. PMID 10380922 DOI: 10.1016/S0092-8674(00)80782-5  0.499
1999 Herz J, Farese RV. The LDL receptor gene family, apolipoprotein B and cholesterol in embryonic development Journal of Nutrition. 129. PMID 10064312 DOI: 10.1093/Jn/129.2.473S  0.387
1999 van Vlijmen BJ, Herz J. Gene targets and approaches for raising HDL. Circulation. 99: 12-4. PMID 9884371 DOI: 10.1161/01.Cir.99.1.12  0.346
1999 SATO A, SHIMADA Y, HERZ J, YAMAMOTO T, JINGAMI H. 39-kDa receptor-associated protein (RAP) facilitates secretion and ligand binding of extracellular region of very-low-density-lipoprotein receptor: implications for a distinct pathway from low-density-lipoprotein receptor Biochemical Journal. 341: 377. DOI: 10.1042/0264-6021:3410377  0.491
1999 Herz J. Analysis of lipoprotein removal pathways in transgenic and knockout mice Atherosclerosis. 144: 165. DOI: 10.1016/S0021-9150(99)80629-7  0.354
1998 Trommsdorff M, Borg JP, Margolis B, Herz J. Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein Journal of Biological Chemistry. 273: 33556-33560. PMID 9837937 DOI: 10.1074/Jbc.273.50.33556  0.496
1998 Véniant MM, Zlot CH, Walzem RL, Pierotti V, Driscoll R, Dichek D, Herz J, Young SG. Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice. The Journal of Clinical Investigation. 102: 1559-68. PMID 9788969 DOI: 10.1172/Jci4164  0.411
1998 Hiesberger T, Hüttler S, Rohlmann A, Schneider W, Sandhoff K, Herz J. Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP). The Embo Journal. 17: 4617-25. PMID 9707421 DOI: 10.1093/Emboj/17.16.4617  0.494
1998 Rohlmann A, Gotthardt M, Willnow TE, Hammer RE, Herz J. Sustained somatic gene inactivation by viral transfer of Cre recombinase. Nature Biotechnology. 14: 1562-5. PMID 9634821 DOI: 10.1038/Nbt1196-1562  0.345
1998 Farese RV, Herz J. Cholesterol metabolism and embryogenesis Trends in Genetics. 14: 115-120. PMID 9540409 DOI: 10.1016/S0168-9525(97)01377-2  0.384
1998 Rohlmann A, Gotthardt M, Hammer RE, Herz J. Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. The Journal of Clinical Investigation. 101: 689-95. PMID 9449704 DOI: 10.1172/Jci1240  0.496
1997 Storm D, Herz J, Trinder P, Loos M. C1 inhibitor-C1s complexes are internalized and degraded by the low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 272: 31043-50. PMID 9388254 DOI: 10.1016/S0161-5890(98)90706-4  0.378
1997 Rigotti A, Trigatti BL, Penman M, Rayburn H, Herz J, Krieger M. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism Proceedings of the National Academy of Sciences of the United States of America. 94: 12610-12615. PMID 9356497 DOI: 10.1073/Pnas.94.23.12610  0.607
1997 Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, Horton JD. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. The Journal of Clinical Investigation. 100: 2115-24. PMID 9329978 DOI: 10.1172/Jci119746  0.595
1997 Brown MS, Herz J, Goldstein JL. LDL-receptor structure. Calcium cages, acid baths and recycling receptors. Nature. 388: 629-30. PMID 9262394 DOI: 10.1038/41672  0.612
1997 Brandes C, Novak S, Stockinger W, Herz J, Schneider WJ, Nimpf J. Avian and murine LR8B and human apolipoprotein E receptor 2: differentially spliced products from corresponding genes. Genomics. 42: 185-91. PMID 9192837 DOI: 10.1006/Geno.1997.4702  0.491
1997 Johnson RC, Chapman SM, Dong ZM, Ordovas JM, Mayadas TN, Herz J, Hynes RO, Schaefer EJ, Wagner DD. Absence of P-selectin delays fatty streak formation in mice. The Journal of Clinical Investigation. 99: 1037-43. PMID 9062362 DOI: 10.1172/Jci119231  0.347
1997 Herz J, Willnow TE, Farese RV. Cholesterol, hedgehog and embryogenesis. Nature Genetics. 15: 123-4. PMID 9020834 DOI: 10.1038/Ng0297-123  0.324
1997 Meiner VL, Cases S, Myers HM, Sande ER, Bellosta S, Schambelan M, Pitas RE, McGuire J, Herz J, Farese RV. Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals. Proceedings of the National Academy of Sciences of the United States of America. 93: 14041-6. PMID 8943057 DOI: 10.1073/Pnas.93.24.14041  0.371
1996 Sinnis P, Willnow TT, Briones MRS, Herz J, Nussenzweig V. Remnant lipoproteins inhibits malaria sporozoite invasion of hepatocytes Journal of Experimental Medicine. 184: 945-954. PMID 9064354 DOI: 10.1084/Jem.184.3.945  0.419
1996 Warshawsky I, Herz J, Broze GJ, Schwartz AL. The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis. The Journal of Biological Chemistry. 271: 25873-9. PMID 8824219 DOI: 10.1074/Jbc.271.42.25873  0.387
1996 Willnow TE, Hilpert J, Armstrong SA, Rohlmann A, Hammer RE, Burns DK, Herz J. Defective forebrain development in mice lacking gp330/megalin. Proceedings of the National Academy of Sciences of the United States of America. 93: 8460-4. PMID 8710893 DOI: 10.1073/Pnas.93.16.8460  0.625
1996 Braun JR, Willnow TE, Ishibashi S, Ashwell G, Herz J. The major subunit of the asialoglycoprotein receptor is expressed on the hepatocellular surface in mice lacking the minor receptor subunit Journal of Biological Chemistry. 271: 21160-21166. PMID 8702886 DOI: 10.1074/Jbc.271.35.21160  0.442
1996 Schwarz M, Lund EG, Setchell KDR, Kayden HJ, Zerwekh JE, Björkhem I, Herz J, Russell DW. Disruption of cholesterol 7α-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7α-hydroxylase Journal of Biological Chemistry. 271: 18024-18031. PMID 8663430 DOI: 10.1074/Jbc.271.30.18024  0.354
1996 Ishibashi S, Schwarz M, Frykman PK, Herz J, Russell DW. Disruption of cholesterol 7α-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation Journal of Biological Chemistry. 271: 18017-18023. PMID 8663429 DOI: 10.1074/Jbc.271.30.18017  0.332
1996 Woollett LA, Osono Y, Herz J, Dietschy JM. Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 92: 12500-4. PMID 8618929 DOI: 10.1073/Pnas.92.26.12500  0.404
1996 Willnow TE, Moehring JM, Inocencio NM, Moehring TJ, Herz J. The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro. The Biochemical Journal. 71-6. PMID 8546712 DOI: 10.1042/Bj3130071  0.459
1996 Willnow TE, Rohlmann A, Horton J, Otani H, Braun JR, Hammer RE, Herz J. RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors. The Embo Journal. 15: 2632-2639. DOI: 10.1002/J.1460-2075.1996.Tb00623.X  0.502
1995 Osono Y, Woollett LA, Herz J, Dietschy JM. Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse. The Journal of Clinical Investigation. 95: 1124-32. PMID 7883961 DOI: 10.1172/Jci117760  0.401
1995 Poller W, Willnow TE, Hilpert J, Herz J. Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 270: 2841-5. PMID 7852358 DOI: 10.1074/Jbc.270.6.2841  0.343
1995 Willnow TE, Herz J. Homologous recombination for gene replacement in mouse cell lines. Methods in Cell Biology. 305-34. PMID 7823869 DOI: 10.1016/S0091-679X(08)60610-X  0.313
1995 Rosahl TW, Spillane D, Missler M, Herz J, Selig DK, Wolff JR, Hammer RE, Malenka RC, Südhof TC. Essential functions of synapsins I and II in synaptic vesicle regulation. Nature. 375: 488-93. PMID 7777057 DOI: 10.1038/375488A0  0.493
1995 Herz J, Willnow TE. Lipoprotein and receptor interactions in vivo. Current Opinion in Lipidology. 6: 97-103. PMID 7773575 DOI: 10.1097/00041433-199504000-00007  0.427
1995 Herz J, Qiu SQ, Oesterle A, DeSilva HV, Shafi S, Havel RJ. Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 4611-5. PMID 7753850 DOI: 10.1073/Pnas.92.10.4611  0.478
1995 Willnow TE, Herz J. Animal models for disorders of hepatic lipoprotein metabolism. Journal of Molecular Medicine (Berlin, Germany). 73: 213-20. PMID 7670924 DOI: 10.1007/Bf00189920  0.442
1995 Frykman PK, Brown MS, Yamamoto T, Goldstein JL, Herz J. Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 8453-7. PMID 7667310 DOI: 10.1073/Pnas.92.18.8453  0.657
1995 Narita M, Bu G, Herz J, Schwartz AL. Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo Journal of Clinical Investigation. 96: 1164-1168. PMID 7635954 DOI: 10.1172/Jci118105  0.394
1995 Narita M, Bu G, Olins GM, Higuchi DA, Herz J, Broze GJ, Schwartz AL. Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo. The Journal of Biological Chemistry. 270: 24800-4. PMID 7559599 DOI: 10.1074/Jbc.270.42.24800  0.336
1995 Willnow TE, Armstrong SA, Hammer RE, Herz J. Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo Proceedings of the National Academy of Sciences of the United States of America. 92: 4537-4541. PMID 7538675 DOI: 10.1073/Pnas.92.10.4537  0.673
1995 Hilpert J, Willnow T, Jonat S, Herz J, Beisiegel U. Lipoprotein uptake in mouse fibroblasts lacking the LDL receptor, the LRP or both Atherosclerosis. 115: S38. DOI: 10.1016/0021-9150(95)96401-D  0.485
1995 Herz J, Willnow TE. Gene transfer and disruption strategies to elucidate hepatic lipoprotein receptor functions Atherosclerosis. 118: S37-S41. DOI: 10.1016/0021-9150(95)90071-3  0.381
1994 Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS. The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 4431-5. PMID 8183926 DOI: 10.1073/Pnas.91.10.4431  0.651
1994 Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. The Journal of Clinical Investigation. 93: 1885-93. PMID 8182121 DOI: 10.1172/Jci117179  0.618
1994 Krieger M, Herz J. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Annual Review of Biochemistry. 63: 601-37. PMID 7979249 DOI: 10.1146/Annurev.Bi.63.070194.003125  0.471
1994 Herz J, Willnow TE. Functions of the LDL receptor gene family. Annals of the New York Academy of Sciences. 737: 14-9. PMID 7944143 DOI: 10.1111/J.1749-6632.1994.Tb44298.X  0.401
1994 Willnow TE, Sheng Z, Ishibashi S, Herz J. Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science (New York, N.Y.). 264: 1471-4. PMID 7515194 DOI: 10.1126/Science.7515194  0.503
1994 Willnow T, Orth K, Herz J. Analysis of ligand binding to the LDL receptor-related protein (LRP) Atherosclerosis. 109: 175-176. DOI: 10.1016/0021-9150(94)93707-9  0.417
1993 Herz J, Gerard RD. Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 2812-6. PMID 8464893 DOI: 10.1073/Pnas.90.7.2812  0.485
1993 Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. The Journal of Clinical Investigation. 92: 883-93. PMID 8349823 DOI: 10.1172/Jci116663  0.667
1993 Rosahl TW, Geppert M, Spillane D, Herz J, Hammer RE, Malenka RC, Südhof TC. Short-term synaptic plasticity is altered in mice lacking synapsin I. Cell. 75: 661-70. PMID 7902212 DOI: 10.1016/0092-8674(93)90487-B  0.517
1993 Herz J. The LDL-receptor-related protein ??? portrait of a multifunctional receptor Current Opinion in Lipidology. 4: 107-113. DOI: 10.1097/00041433-199304000-00006  0.461
1992 Orth K, Madison EL, Gething MJ, Sambrook JF, Herz J. Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 7422-6. PMID 1502153 DOI: 10.1073/Pnas.89.16.7422  0.38
1992 Willnow TE, Goldstein JL, Orth K, Brown MS, Herz J. Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. The Journal of Biological Chemistry. 267: 26172-80. PMID 1464627  0.604
1992 Herz J, Clouthier DE, Hammer RE. LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell. 71: 411-21. PMID 1423604 DOI: 10.1016/0092-8674(92)90511-A  0.394
1992 Paulien S, Sandberg AA, Herz J, Gemmill RM. Putative apolipoprotein receptor gene (LRP, A2MR) is not rearranged in either myxoid liposarcoma or lipomas with translocations in 12q13-14. Cancer Genetics and Cytogenetics. 60: 125-30. PMID 1318779 DOI: 10.1016/0165-4608(92)90003-Q  0.343
1991 Herz J, Goldstein JL, Strickland DK, Ho YK, Brown MS. 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 266: 21232-8. PMID 1718973  0.597
1991 Brown MS, Herz J, Kowal RC, Goldstein JL. The low-density lipoprotein receptor-related protein: double agent or decoy? Current Opinion in Lipidology. 2: 65-72. DOI: 10.1097/00041433-199104000-00002  0.653
1990 Kowal RC, Herz J, Weisgraber KH, Mahley RW, Brown MS, Goldstein JL. Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 265: 10771-9. PMID 2355022  0.6
1990 Weisgraber KH, Mahley RW, Kowal RC, Herz J, Goldstein JL, Brown MS. Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 265: 22453-9. PMID 2266137  0.539
1990 Herz J, Kowal RC, Ho YK, Brown MS, Goldstein JL. Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver. The Journal of Biological Chemistry. 265: 21355-62. PMID 2250029  0.572
1990 Prehn S, Herz J, Hartmann E, Kurzchalia TV, Frank R, Roemisch K, Dobberstein B, Rapoport TA. Structure and biosynthesis of the signal-sequence receptor. European Journal of Biochemistry / Febs. 188: 439-45. PMID 2156703 DOI: 10.1111/J.1432-1033.1990.Tb15421.X  0.332
1990 Herz J, Kowal RC, Goldstein JL, Brown MS. Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment. The Embo Journal. 9: 1769-76. PMID 2112085 DOI: 10.1002/J.1460-2075.1990.Tb08301.X  0.627
1989 Beisiegel U, Weber W, Ihrke G, Herz J, Stanley KK. The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein. Nature. 341: 162-4. PMID 2779654 DOI: 10.1038/341162A0  0.481
1989 Kowal RC, Herz J, Goldstein JL, Esser V, Brown MS. Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 86: 5810-4. PMID 2762297 DOI: 10.1073/Pnas.86.15.5810  0.648
1989 Kütt H, Herz J, Stanley KK. Structure of the low-density lipoprotein receptor-related protein (LRP) promoter. Biochimica Et Biophysica Acta. 1009: 229-236. PMID 2597675 DOI: 10.1016/0167-4781(89)90107-3  0.493
1989 Myklebost O, Arheden K, Rogne S, Geurts van Kessel A, Mandahl N, Herz J, Stanley K, Heim S, Mitelman F. The gene for the human putative apoE receptor is on chromosome 12 in the segment q13-14. Genomics. 5: 65-9. PMID 2548950 DOI: 10.1016/0888-7543(89)90087-6  0.338
1988 Herz J, Hamann U, Rogne S, Myklebost O, Gausepohl H, Stanley KK. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. The Embo Journal. 7: 4119-4127. DOI: 10.1002/J.1460-2075.1988.Tb03306.X  0.448
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