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Ana M Martinez - Publications

Affiliations: 
Caroi'Line 
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Martínez de Iturrate P, Sebastián-Pérez V, Nácher-Vázquez M, Tremper CS, Smirlis D, Martín J, Martínez A, Campillo NE, Rivas L, Gil C. Towards discovery of new leishmanicidal scaffolds able to inhibit GSK-3. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 199-210. PMID 31752556 DOI: 10.1080/14756366.2019.1693704  0.306
2019 Zaldivar-Diez J, Li L, Garcia AM, Zhao W, Medina-Menendez C, Haggarty SJ, Gil C, Morales AV, Martínez A. BENZOTHIAZOLE-BASED LRRK2 INHIBITORS AS WNT ENHANCERS AND PROMOTERS OF OLIGODENDROCYTIC FATE. Journal of Medicinal Chemistry. PMID 31825616 DOI: 10.1021/Acs.Jmedchem.9B01752  0.302
2019 Sciú ML, Sebastián-Pérez V, Martinez-Gonzalez L, Benitez R, Perez DI, Pérez C, Campillo NE, Martinez A, Moyano EL. Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3. Journal of Enzyme Inhibition and Medicinal Chemistry. 34: 87-96. PMID 30362380 DOI: 10.1080/14756366.2018.1530223  0.309
2018 de Andrade P, Mantoani SP, Gonçalves Nunes PS, Magadán CR, Pérez C, Xavier DJ, Hojo ETS, Campillo NE, Martínez A, Carvalho I. Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease. Bioorganic & Medicinal Chemistry. PMID 30765302 DOI: 10.1016/J.Bmc.2018.12.030  0.326
2018 Uliassi E, Peña-Altamira LE, Morales AV, Massenzio F, Petralla S, Rossi M, Roberti M, Martínez-González L, Martínez A, Monti B, Bolognesi ML. A focused library of psychotropic analogs with neuroprotective and neuroregenerative potential. Acs Chemical Neuroscience. PMID 30253086 DOI: 10.1021/Acschemneuro.8B00242  0.304
2018 Benek O, Hroch L, Aitken L, Gunn-Moore F, Vinklarova L, Kuca K, Perez DI, Perez C, Martinez A, Fisar Z, Musilek K. 1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 665-670. PMID 29536773 DOI: 10.1080/14756366.2018.1445736  0.324
2016 Silva TB, Mohamed T, Shakeri A, Rao PP, Martínez-González L, Pérez DI, Martínez A, Valente MJ, Garrido J, Uriarte E, Serrão P, Soares-da-Silva P, Remião F, Borges FM. Development of blood brain barrier permeable nitrocatechol-based catechol O-methyltransferase inhibitors with reduced potential for hepatotoxicity. Journal of Medicinal Chemistry. PMID 27463695 DOI: 10.1021/Acs.Jmedchem.6B00666  0.303
2016 Reina M, Martinez A. Is Silybin the Best Free Radical Scavenger Compound in Silymarin? The Journal of Physical Chemistry. B. PMID 27149000 DOI: 10.1021/Acs.Jpcb.6B02807  0.306
2016 Mantoani SP, Chierrito TP, Vilela AF, Cardoso CL, Martínez A, Carvalho I. Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. Molecules (Basel, Switzerland). 21. PMID 26861273 DOI: 10.3390/Molecules21020193  0.313
2015 Prati F, De Simone A, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Bertozzi SM, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Sabatino P, ... ... Martinez A, et al. 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease. Acs Chemical Neuroscience. PMID 26171616 DOI: 10.1021/Acschemneuro.5B00121  0.315
2015 Silva T, Bravo J, Summavielle T, Remião F, Pérez C, Gil C, Martínez A, Borges F. Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity Rsc Advances. 5: 15800-15811. DOI: 10.1039/C4Ra15164J  0.316
2014 García AM, Brea J, Morales-García JA, Perez DI, González A, Alonso-Gil S, Gracia-Rubio I, Ros-Simó C, Conde S, Cadavid MI, Loza MI, Perez-Castillo A, Valverde O, Martinez A, Gil C. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors. Journal of Medicinal Chemistry. 57: 8590-607. PMID 25264825 DOI: 10.1021/Jm501090M  0.311
2012 Redondo M, Brea J, Perez DI, Soteras I, Val C, Perez C, Morales-García JA, Alonso-Gil S, Paul-Fernandez N, Martin-Alvarez R, Cadavid MI, Loza MI, Perez-Castillo A, Mengod G, Campillo NE, ... Martinez A, et al. Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds. Journal of Medicinal Chemistry. 55: 3274-84. PMID 22385507 DOI: 10.1021/Jm201720D  0.3
2012 Chiriano G, De Simone A, Mancini F, Perez DI, Cavalli A, Bolognesi ML, Legname G, Martinez A, Andrisano V, Carloni P, Roberti M. A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation. European Journal of Medicinal Chemistry. 48: 206-13. PMID 22209418 DOI: 10.1016/J.Ejmech.2011.12.016  0.308
2012 Martínez A, Conde E, Moure A, Domínguez H, Estévez RJ. Protective effect against oxygen reactive species and skin fibroblast stimulation of Couroupita guianensis leaf extracts. Natural Product Research. 26: 314-22. PMID 21432721 DOI: 10.1080/14786411003752094  0.578
2012 Martínez A, Estévez JC, Silva-Pando FJ. Antioxidant activity, total phenolic content and skin care properties of 35 selected plants from Galicia (NW Spain) Frontiers in Life Science. 6: 77-86. DOI: 10.1080/21553769.2013.776994  0.583
2011 López-Munguía A, Hernández-Romero Y, Pedraza-Chaverri J, Miranda-Molina A, Regla I, Martínez A, Castillo E. Phenylpropanoid Glycoside Analogues: Enzymatic Synthesis, Antioxidant Activity and Theoretical Study of Their Free Radical Scavenger Mechanism Plos One. 6. PMID 21674039 DOI: 10.1371/Journal.Pone.0020115  0.312
2011 Perez DI, Palomo V, Pérez C, Gil C, Dans PD, Luque FJ, Conde S, Martínez A. Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds. Journal of Medicinal Chemistry. 54: 4042-4056. PMID 21500862 DOI: 10.1021/Jm1016279  0.309
2009 Perez DI, Conde S, Pérez C, Gil C, Simon D, Wandosell F, Moreno FJ, Gelpí JL, Luque FJ, Martínez A. Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools Bioorganic & Medicinal Chemistry. 17: 6914-6925. PMID 19747834 DOI: 10.1016/J.Bmc.2009.08.042  0.302
2009 Castaño T, Wang H, Campillo NE, Ballester S, González-García C, Hernández J, Pérez C, Cuenca J, Pérez-Castillo A, Martínez A, Huertas O, Gelpí JL, Luque FJ, Ke H, Gil C. Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors. Chemmedchem. 4: 866-76. PMID 19350606 DOI: 10.1002/Cmdc.200900043  0.319
2008 Dacunha-Marinho B, Martínez A, Estévez RJ. 7-hydroxy-5-methoxy-6,8-dimethylflavanone: a natural flavonoid. Acta Crystallographica. Section C, Crystal Structure Communications. 64: o353-6. PMID 18535347 DOI: 10.1107/S0108270108014959  0.548
2008 Castro A, Jerez MJ, Gil C, Calderón F, Doménech T, Nueda A, Martínez A. CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example. European Journal of Medicinal Chemistry. 43: 1349-1359. PMID 18082290 DOI: 10.1016/J.Ejmech.2007.10.027  0.31
2007 Martínez A, Barcia JC, Estévez AM, Fernández F, González L, Estévez JC, Estévez RJ. A novel approach to the synthesis of benzo[b]fluoren-11-ones Tetrahedron Letters. 48: 2147-2149. DOI: 10.1016/J.Tetlet.2007.01.112  0.752
2005 Martinez A, Alonso M, Castro A, Dorronsoro I, Gelpi JL, Luque FJ, Perez C, Moreno FJ. SAR and 3D-QSAR Studies on Thiadiazolidinone Derivatives: Exploration of Structural Requirements for Glycogen Synthase Kinase 3 Inhibitors Journal of Medicinal Chemistry. 48: 7103-7112. PMID 16279768 DOI: 10.1021/Jm040895G  0.313
2005 Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Castro A, Martínez A. Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase. Bioorganic & Medicinal Chemistry. 13: 6795-6802. PMID 16183292 DOI: 10.1016/J.Bmc.2005.07.019  0.304
2005 Dorronsoro I, Alonso D, Castro A, Monte Md, García-Palomero E, Martínez A. Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors. Archiv Der Pharmazie. 338: 18-23. PMID 15674800 DOI: 10.1002/Ardp.200400919  0.308
2005 Martínez A, Fernández M, Estévez JC, Estévez RJ, Castedo L. New ‘2-phenylnaphthalene’-mediated synthesis of benzo[b]naphtho[2,3-d]furan-6,11-diones and 6-oxa-benzo[a]anthracene-5,7,12-triones: first total synthesis of 6-oxa-benzo[a]anthracen-5-ones Tetrahedron. 61: 1353-1362. DOI: 10.1016/J.Tet.2004.10.044  0.711
2005 Martínez A, Fernández M, Estévez JC, Estévez RJ, Castedo L. Studies on the chemistry of 2-(2-oxo-3-phenylpropyl)-benzaldehydes: novel total synthesis of 3-phenylnaphthalen-2-ols and 2-hydroxy-3-phenyl-1,4-naphthoquinones Tetrahedron. 61: 485-492. DOI: 10.1016/J.Tet.2004.10.043  0.719
2003 Conde S, Perez DI, Martinez A, Perez C, Moreno FJ. Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3beta) from a library of compound searching. Journal of Medicinal Chemistry. 46: 4631-4633. PMID 14561081 DOI: 10.1021/Jm034108B  0.315
2003 Martinez A, Gil C, Castro A, Bruno AM, Pérez C, Prieto C, Otero J. Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives. Antiviral Chemistry & Chemotherapy. 14: 107-14. PMID 12856922 DOI: 10.1177/095632020301400206  0.319
2003 Martinez A, Gil C, Castro A, Pérez C, Prieto C, Otero J. Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. study of structural requirements for biological activity. Bioorganic & Medicinal Chemistry. 11: 2395-2402. PMID 12735985 DOI: 10.1016/S0968-0896(03)00148-2  0.318
2000 Martinez A, Gil C, Abasolo MI, Castro A, Bruno AM, Perez C, Prieto C, Otero J. Benzothiadiazine dioxide dibenzyl derivatives as potent human cytomegalovirus inhibitors: synthesis and comparative molecular field analysis. Journal of Medicinal Chemistry. 43: 3218-25. PMID 10966740 DOI: 10.1021/Jm000033P  0.332
1999 Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J. Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors. Bioorganic & Medicinal Chemistry Letters. 9: 3133-3136. PMID 10560739 DOI: 10.1016/S0960-894X(99)00538-7  0.305
1998 Segarra V, Crespo MI, Pujol F, Beleta J, Doménech T, Miralpeix M, Palacios JM, Castro A, Martinez A. Phosphodiesterase inhibitory properties of losartan. Design and synthesis of new lead compounds. Bioorganic & Medicinal Chemistry Letters. 8: 505-10. PMID 9871607 DOI: 10.1016/S0960-894X(98)00058-4  0.301
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