Nabil Alkayed - Publications

Affiliations: 
Oregon Health and Science University, Portland, OR 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Le DE, Davis CM, Wei K, Zhao Y, Cao Z, Nugent M, Scott KL, Liu L, Nagarajan S, Alkayed NJ, Kaul S. Ranolazine May Exert its Beneficial Effects by Increasing Myocardial Adenosine Levels. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31834840 DOI: 10.1152/ajpheart.00217.2019  0.48
2017 Davis CM, Liu X, Alkayed NJ. Cytochrome P450 Eicosanoids in Cerebrovascular Function and Disease. Pharmacology & Therapeutics. PMID 28527918 DOI: 10.1016/j.pharmthera.2017.05.004  0.48
2017 Liu X, Davis CM, Alkayed NJ. P450 EICOSANOIDS AND ROS INTERPLAY IN BRAIN INJURY AND NEUROPROTECTION. Antioxidants & Redox Signaling. PMID 28298143 DOI: 10.1089/ars.2017.7056  0.48
2016 Baran U, Zhu W, Choi WJ, Omori M, Zhang W, Alkayed NJ, Wang RK. Automated segmentation and enhancement of optical coherence tomography-acquired images of rodent brain. Journal of Neuroscience Methods. PMID 27328369 DOI: 10.1016/j.jneumeth.2016.06.014  0.48
2016 Nelson JW, Das AJ, Barnes AP, Alkayed NJ. Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes. Plos One. 11: e0152742. PMID 27203283 DOI: 10.1371/journal.pone.0152742  0.48
2016 Jia J, Davis CM, Zhang W, Edin ML, Jouihan S, Jia T, Bradbury JA, Graves JP, DeGraff LM, Lee CR, Ronnekleiv O, Wang R, Xu Y, Zeldin DC, Alkayed NJ. Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium. Experimental Neurology. PMID 26902473 DOI: 10.1016/j.expneurol.2016.02.016  0.48
2016 Johnson LA, Zuloaga KL, Kugelman TL, Mader KS, Morré JT, Zuloaga DG, Weber S, Marzulla T, Mulford A, Button D, Lindner JR, Alkayed NJ, Stevens JF, Raber J. Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma. Ebiomedicine. 3: 26-42. PMID 26870815 DOI: 10.1016/j.ebiom.2015.12.008  0.48
2015 Zuloaga KL, Johnson LA, Roese NE, Marzulla T, Zhang W, Nie X, Alkayed FN, Hong C, Grafe MR, Pike MM, Raber J, Alkayed NJ. High fat diet-induced diabetes in mice exacerbates cognitive deficit due to chronic hypoperfusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661233 DOI: 10.1177/0271678X15616400  0.48
2015 Chen Y, Zhu W, Zhang W, Libal N, Murphy SJ, Offner H, Alkayed NJ. A Novel Mouse Model of Thromboembolic Stroke. Journal of Neuroscience Methods. PMID 26386284 DOI: 10.1016/j.jneumeth.2015.09.013  0.48
2015 Nelson JW, Zhang W, Alkayed NJ, Koerner IP. Peroxisomal translocation of soluble epoxide hydrolase protects against ischemic stroke injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26126869 DOI: 10.1038/jcbfm.2015.159  0.48
2015 Davis CM, Ammi AY, Alkayed NJ, Kaul S. Ultrasound stimulates formation and release of vasoactive compounds in brain endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00690.2014. PMID 26092990 DOI: 10.1152/ajpheart.00690.2014  0.48
2015 Zuloaga KL, Zhang W, Yeiser LA, Stewart B, Kukino A, Nie X, Roese NE, Grafe MR, Pike MM, Raber J, Alkayed NJ. Neurobehavioral and Imaging Correlates of Hippocampal Atrophy in a Mouse Model of Vascular Cognitive Impairment. Translational Stroke Research. PMID 26040424 DOI: 10.1007/s12975-015-0412-z  0.48
2015 Siler DA, Berlow YA, Kukino A, Davis CM, Nelson JW, Grafe MR, Ono H, Cetas JS, Pike M, Alkayed NJ. Soluble Epoxide Hydrolase in Hydrocephalus, Cerebral Edema, and Vascular Inflammation After Subarachnoid Hemorrhage. Stroke; a Journal of Cerebral Circulation. 46: 1916-22. PMID 25991416 DOI: 10.1161/STROKEAHA.114.008560  0.48
2015 Xie H, Xu Q, Jia J, Ao G, Sun Y, Hu L, Alkayed NJ, Wang C, Cheng J. Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux. Biochemical and Biophysical Research Communications. 458: 632-8. PMID 25684185 DOI: 10.1016/j.bbrc.2015.02.017  0.48
2015 Zhu W, Casper A, Libal NL, Murphy SJ, Bodhankar S, Offner H, Alkayed NJ. Preclinical evaluation of recombinant T cell receptor ligand RTL1000 as a therapeutic agent in ischemic stroke. Translational Stroke Research. 6: 60-8. PMID 25270354 DOI: 10.1007/s12975-014-0373-7  0.48
2015 Siler DA, Martini RP, Ward JP, Nelson JW, Borkar RN, Zuloaga KL, Liu JJ, Fairbanks SL, Raskin JS, Anderson VC, Dogan A, Wang RK, Alkayed NJ, Cetas JS. Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. Neurocritical Care. 22: 306-19. PMID 25231529 DOI: 10.1007/s12028-014-0011-y  0.48
2015 Young JM, Nelson JW, Cheng J, Zhang W, Mader S, Davis CM, Morrison RS, Alkayed NJ. Peroxisomal biogenesis in ischemic brain. Antioxidants & Redox Signaling. 22: 109-20. PMID 25226217 DOI: 10.1089/ars.2014.5833  0.48
2014 Zuloaga KL, Zhang W, Roese NE, Alkayed NJ. Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice. Frontiers in Pharmacology. 5: 290. PMID 25642188 DOI: 10.3389/fphar.2014.00290  0.48
2014 Shim CY, Kim S, Chadderdon S, Wu M, Qi Y, Xie A, Alkayed NJ, Davidson BP, Lindner JR. Epoxyeicosatrienoic acids mediate insulin-mediated augmentation in skeletal muscle perfusion and blood volume. American Journal of Physiology. Endocrinology and Metabolism. 307: E1097-104. PMID 25336524 DOI: 10.1152/ajpendo.00216.2014  0.48
2014 Dotson AL, Zhu W, Libal N, Alkayed NJ, Offner H. Different immunological mechanisms govern protection from experimental stroke in young and older mice with recombinant TCR ligand therapy. Frontiers in Cellular Neuroscience. 8: 284. PMID 25309326 DOI: 10.3389/fncel.2014.00284  0.48
2014 Nelson JW, Young JM, Borkar RN, Woltjer RL, Quinn JF, Silbert LC, Grafe MR, Alkayed NJ. Role of soluble epoxide hydrolase in age-related vascular cognitive decline. Prostaglandins & Other Lipid Mediators. 113: 30-7. PMID 25277097 DOI: 10.1016/j.prostaglandins.2014.09.003  0.48
2014 Martini RP, Ward J, Siler DA, Eastman JM, Nelson JW, Borkar RN, Alkayed NJ, Dogan A, Cetas JS. Genetic variation in soluble epoxide hydrolase: association with outcome after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 121: 1359-66. PMID 25216066 DOI: 10.3171/2014.7.JNS131990  0.48
2014 Zhu W, Libal NL, Casper A, Bodhankar S, Offner H, Alkayed NJ. Recombinant T cell receptor ligand treatment improves neurological outcome in the presence of tissue plasminogen activator in experimental ischemic stroke. Translational Stroke Research. 5: 612-7. PMID 24953050 DOI: 10.1007/s12975-014-0348-8  0.48
2014 Hutchens MP, Kosaka Y, Zhang W, Fujiyoshi T, Murphy S, Alkayed N, Anderson S. Estrogen-mediated renoprotection following cardiac arrest and cardiopulmonary resuscitation is robust to GPR30 gene deletion. Plos One. 9: e99910. PMID 24923556 DOI: 10.1371/journal.pone.0099910  0.48
2014 Zuloaga KL, Krasnow SM, Zhu X, Zhang W, Jouihan SA, Shangraw RE, Alkayed NJ, Marks DL. Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke. Plos One. 9: e97529. PMID 24824753 DOI: 10.1371/journal.pone.0097529  0.48
2014 Wang Y, Jia J, Ao G, Hu L, Liu H, Xiao Y, Du H, Alkayed NJ, Liu CF, Cheng J. Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia. Journal of Neurochemistry. 129: 827-38. PMID 24673410 DOI: 10.1111/jnc.12695  0.48
2014 Zhou X, Cao Y, Ao G, Hu L, Liu H, Wu J, Wang X, Jin M, Zheng S, Zhen X, Alkayed NJ, Jia J, Cheng J. CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. Antioxidants & Redox Signaling. 21: 1741-58. PMID 24624937 DOI: 10.1089/ars.2013.5587  0.48
2014 Siler DA, Gonzalez JA, Wang RK, Cetas JS, Alkayed NJ. Intracisternal administration of tissue plasminogen activator improves cerebrospinal fluid flow and cortical perfusion after subarachnoid hemorrhage in mice. Translational Stroke Research. 5: 227-37. PMID 24526376 DOI: 10.1007/s12975-014-0329-y  0.48
2014 Zuloaga KL, Davis CM, Zhang W, Alkayed NJ. Role of aromatase in sex-specific cerebrovascular endothelial function in mice. American Journal of Physiology. Heart and Circulatory Physiology. 306: H929-37. PMID 24508640 DOI: 10.1152/ajpheart.00698.2013  0.48
2014 Benedek G, Zhu W, Libal N, Casper A, Yu X, Meza-Romero R, Vandenbark AA, Alkayed NJ, Offner H. A novel HLA-DRα1-MOG-35-55 construct treats experimental stroke. Metabolic Brain Disease. 29: 37-45. PMID 24122483 DOI: 10.1007/s11011-013-9440-0  0.48
2013 Jouihan SA, Zuloaga KL, Zhang W, Shangraw RE, Krasnow SM, Marks DL, Alkayed NJ. Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1650-6. PMID 23899929 DOI: 10.1038/jcbfm.2013.130  0.48
2013 Davis CM, Fairbanks SL, Alkayed NJ. Mechanism of the sex difference in endothelial dysfunction after stroke. Translational Stroke Research. 4: 381-9. PMID 23853671 DOI: 10.1007/s12975-012-0227-0  0.48
2013 Jia J, Xiao Y, Wang W, Qing L, Xu Y, Song H, Zhen X, Ao G, Alkayed NJ, Cheng J. Differential mechanisms underlying neuroprotection of hydrogen sulfide donors against oxidative stress. Neurochemistry International. 62: 1072-8. PMID 23587562 DOI: 10.1016/j.neuint.2013.04.001  0.48
2013 Zhang W, Davis CM, Edin ML, Lee CR, Zeldin DC, Alkayed NJ. Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury. Plos One. 8: e61244. PMID 23585883 DOI: 10.1371/journal.pone.0061244  0.48
2013 Nelson JW, Subrahmanyan RM, Summers SA, Xiao X, Alkayed NJ. Soluble epoxide hydrolase dimerization is required for hydrolase activity. The Journal of Biological Chemistry. 288: 7697-703. PMID 23362272 DOI: 10.1074/jbc.M112.429258  0.48
2012 Gupta NC, Davis CM, Nelson JW, Young JM, Alkayed NJ. Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1936-42. PMID 22723436 DOI: 10.1161/ATVBAHA.112.251520  0.48
2012 Chen Y, Bodhankar S, Murphy SJ, Vandenbark AA, Alkayed NJ, Offner H. Intrastriatal B-cell administration limits infarct size after stroke in B-cell deficient mice. Metabolic Brain Disease. 27: 487-93. PMID 22618587 DOI: 10.1007/s11011-012-9317-7  0.48
2012 Di Domenico F, Casalena G, Jia J, Sultana R, Barone E, Cai J, Pierce WM, Cini C, Mancuso C, Perluigi M, Davis CM, Alkayed NJ, Butterfield DA, Butterfield AD. Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion. Journal of Neurochemistry. 121: 680-92. PMID 22394374 DOI: 10.1111/j.1471-4159.2012.07721.x  0.48
2011 Davis CM, Siler DA, Alkayed NJ. Endothelium-derived hyperpolarizing factor in the brain: influence of sex, vessel size and disease state. Women's Health (London, England). 7: 293-303. PMID 21612351 DOI: 10.2217/whe.11.26  0.48
2011 Abdu E, Bruun DA, Yang D, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. Journal of Neurochemistry. 117: 632-42. PMID 21155804 DOI: 10.1111/j.1471-4159.2010.07139.x  0.48
2011 Jia Y, Grafe MR, Gruber A, Alkayed NJ, Wang RK. In vivo optical imaging of revascularization after brain trauma in mice. Microvascular Research. 81: 73-80. PMID 21075124 DOI: 10.1016/j.mvr.2010.11.003  0.48
2010 Di Domenico F, Casalena G, Sultana R, Cai J, Pierce WM, Perluigi M, Cini C, Baracca A, Solaini G, Lenaz G, Jia J, Dziennis S, Murphy SJ, Alkayed NJ, Butterfield DA. Involvement of Stat3 in mouse brain development and sexual dimorphism: a proteomics approach. Brain Research. 1362: 1-12. PMID 20875800 DOI: 10.1016/j.brainres.2010.09.074  0.48
2010 Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, et al. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3770-81. PMID 20495177 DOI: 10.1096/fj.10-160119  0.48
2009 Jia Y, Alkayed N, Wang RK. Potential of optical microangiography to monitor cerebral blood perfusion and vascular plasticity following traumatic brain injury in mice in vivo Journal of Biomedical Optics. 14. PMID 19725710 DOI: 10.1117/1.3207121  0.48
2009 Zhang W, Iliff JJ, Campbell CJ, Wang RK, Hurn PD, Alkayed NJ. Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1475-81. PMID 19471280 DOI: 10.1038/jcbfm.2009.65  0.48
2008 Liu X, Zhang W, Alkayed NJ, Froehner SC, Adams ME, Amiry-Moghaddam M, Ottersen OP, Hurn PD, Bhardwaj A. Lack of sex-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1898-906. PMID 18648381 DOI: 10.1038/jcbfm.2008.83  0.48
2008 Dziennis S, Yang D, Cheng J, Anderson KA, Alkayed NJ, Hurn PD, Lein PJ. Developmental exposure to polychlorinated biphenyls influences stroke outcome in adult rats. Environmental Health Perspectives. 116: 474-80. PMID 18414629 DOI: 10.1289/ehp.10828  0.48
2008 Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop DR, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 39: 2073-8. PMID 18369166 DOI: 10.1161/STROKEAHA.107.508325  0.48
2008 Koerner IP, Zhang W, Cheng J, Parker S, Hurn PD, Alkayed NJ. Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2833-41. PMID 17981757 DOI: 10.2741/2889  0.48
2007 Iliff JJ, Close LN, Selden NR, Alkayed NJ. A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat. Experimental Physiology. 92: 653-8. PMID 17639071 DOI: 10.1113/expphysiol.2006.036889  0.48
2007 Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1931-40. PMID 17440491 DOI: 10.1038/sj.jcbfm.9600494  0.48
2007 Liu M, Hurn PD, Roselli CE, Alkayed NJ. Role of P450 aromatase in sex-specific astrocytic cell death. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 135-41. PMID 16736049 DOI: 10.1038/sj.jcbfm.9600331  0.48
2006 Xu Y, Zhang W, Klaus J, Young J, Koerner I, Sheldahl LC, Hurn PD, Martínez-Murillo F, Alkayed NJ. Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection. Proceedings of the National Academy of Sciences of the United States of America. 103: 14489-94. PMID 16971488 DOI: 10.1073/pnas.0602932103  0.48
2006 Joh HD, Searles RV, Selmanoff M, Alkayed NJ, Koehler RC, Hurn PD, Murphy SJ. Estradiol alters only GAD67 mRNA levels in ischemic rat brain with no consequent effects on GABA Journal of Cerebral Blood Flow and Metabolism. 26: 518-526. PMID 16094313 DOI: 10.1038/sj.jcbfm.9600211  0.48
2003 Antezana DF, Clatterbuck RE, Alkayed NJ, Murphy SJ, Anderson LG, Frazier J, Hurn PD, Traystman RJ, Tamargo RJ. High-dose ibuprofen for reduction of striatal infarcts during middle cerebral artery occlusion in rats. Journal of Neurosurgery. 98: 860-6. PMID 12691413 DOI: 10.3171/jns.2003.98.4.0860  0.48
2003 Goto S, Sampei K, Alkayed NJ, Doré S, Koehler RC. Characterization of a new double-filament model of focal cerebral ischemia in heme oxygenase-2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R222-30. PMID 12663258 DOI: 10.1152/ajpregu.00067.2003  0.48
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