Stephen H. Tsang, MD, PhD - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Photoreceptors
Website:
http://sklad.cumc.columbia.edu/pharm/cumc/profile_new.php?id=295

227 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hsu KS, Otsu W, Li Y, Wang HC, Chen S, Tsang SH, Chuang JZ, Sung CH. CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells. Scientific Reports. 9: 12247. PMID 31439888 DOI: 10.1038/s41598-019-48438-0  0.68
2019 Philip S, Xu X, Laud KG, Sengillo JD, Tsang SH, Yannuzzi LA. Choroidal neovascularization in an adolescent with -associated retinal degeneration. Ophthalmic Genetics. 1-3. PMID 31424981 DOI: 10.1080/13816810.2019.1655770  0.52
2019 Wert KJ, Koch SF, Velez G, Hsu CW, Mahajan M, Bassuk AG, Tsang SH, Mahajan VB. CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials. Human Mutation. PMID 31403230 DOI: 10.1002/humu.23894  1
2019 Takahashi VKL, Xu CL, Takiuti JT, Apatoff MBL, Duong JK, Mahajan VB, Tsang SH. Comparison of structural progression between ciliopathy and non-ciliopathy associated with autosomal recessive retinitis pigmentosa. Orphanet Journal of Rare Diseases. 14: 187. PMID 31370859 DOI: 10.1186/s13023-019-1163-9  0.44
2019 Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X. HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration. Aging. PMID 31284269 DOI: 10.18632/aging.102039  0.68
2019 Chang YJ, Xu CL, Cui X, Bassuk AG, Mahajan VB, Tsai YT, Tsang SH. CRISPR Base Editing in Induced Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 31250381 DOI: 10.1007/7651_2019_243  0.44
2019 Velez G, Yang J, Li AS, Tsang SH, Bassuk AG, Mahajan VB. Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy. Scientific Reports. 9: 7608. PMID 31110225 DOI: 10.1038/s41598-019-44031-7  0.44
2019 Wert KJ, Bakall B, Bassuk AG, Tsang SH, Mahajan VB. Insights into Retinal Development Using Live Imaging in Female Carriers of Choroideremia. Ophthalmic Surgery, Lasers & Imaging Retina. 50: e158-e162. PMID 31100169 DOI: 10.3928/23258160-20190503-15  0.44
2019 Takahashi VKL, Takiuti JT, Jauregui R, Xu CL, Duong JK, Lima LH, Tsang SH. Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 31049658 DOI: 10.1007/s00417-019-04265-7  0.44
2019 Wang NK, Mahajan VB, Tsang SH. Therapeutic Window for Phosphodiesterase 6-Related Retinitis Pigmentosa. Jama Ophthalmology. PMID 30998807 DOI: 10.1001/jamaophthalmol.2018.6381  0.44
2019 Sancho-Pelluz J, Cui X, Lee W, Tsai YT, Wu WH, Justus S, Washington I, Hsu CW, Park KS, Koch S, Velez G, Bassuk AG, Mahajan VB, Lin CS, Tsang SH. Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a Rho mutation. Cellular and Molecular Life Sciences : Cmls. PMID 30976840 DOI: 10.1007/s00018-019-03090-9  0.6
2019 Wolock CJ, Stong N, Ma CJ, Nagasaki T, Lee W, Tsang SH, Kamalakaran S, Goldstein DB, Allikmets R. A case-control collapsing analysis identifies retinal dystrophy genes associated with ophthalmic disease in patients with no pathogenic ABCA4 variants. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30926958 DOI: 10.1038/s41436-019-0495-0  0.32
2019 Tang PH, Jauregui R, Tsang SH, Bassuk AG, Mahajan VB. Optical Coherence Tomography Angiography of RPGR-Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss. Ophthalmic Surgery, Lasers & Imaging Retina. 50: e44-e48. PMID 30768229 DOI: 10.3928/23258160-20190129-18  0.44
2019 Sengillo JD, Cho GY, Paavo M, Lee W, White E, Jauregui R, Sparrow JR, Allikmets R, Tsang SH. Hyperautofluorescent Dots are Characteristic in Ceramide Kinase Like-associated Retinal Degeneration. Scientific Reports. 9: 876. PMID 30696906 DOI: 10.1038/s41598-018-37578-4  0.52
2019 Tang PH, Velez G, Tsang SH, Bassuk AG, Mahajan VB. VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site. Investigative Ophthalmology & Visual Science. 60: 282-293. PMID 30657523 DOI: 10.1167/iovs.18-25624  0.44
2019 Takahashi VKL, Takiuti JT, Carvalho-Jr JRL, Xu CL, Duong JK, Mahajan VB, Tsang SH. Fundus autofluorescence and ellipsoid zone (EZ) line width can be an outcome measurement in RHO-associated autosomal dominant retinitis pigmentosa. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 30635721 DOI: 10.1007/s00417-018-04234-6  0.44
2019 Xu CL, Ruan MZC, Mahajan VB, Tsang SH. Viral Delivery Systems for CRISPR. Viruses. 11. PMID 30621179 DOI: 10.3390/v11010028  0.44
2018 Tsui I, Song BJ, Lin CS, Tsang SH. A Practical Approach to Retinal Dystrophies. Advances in Experimental Medicine and Biology. 1085: 245-259. PMID 30578524 DOI: 10.1007/978-3-319-95046-4_51  0.6
2018 Cho GY, Bolo K, Park KS, Sengillo JD, Tsang SH. Attenuation of Inherited and Acquired Retinal Degeneration Progression with Gene-based Techniques. Molecular Diagnosis & Therapy. PMID 30569401 DOI: 10.1007/s40291-018-0377-1  0.52
2018 Huang CY, Kang EY, Kuo HC, Chen CM, Lo FS, Yeh LK, Chen KJ, Wang NK, Takahashi VKL, Xu CL, Tsang SH. Diagnostic and Therapeutic Challenges. Retina (Philadelphia, Pa.). PMID 30562245 DOI: 10.1097/IAE.0000000000002414  0.44
2018 Jauregui R, Thomas AL, Liechty B, Velez G, Mahajan VB, Clark L, Tsang SH. SCAPER-associated nonsyndromic autosomal recessive retinitis pigmentosa. American Journal of Medical Genetics. Part A. PMID 30561111 DOI: 10.1002/ajmg.a.61001  0.44
2018 Tang PH, Kinnick TR, Folk JC, Mahajan M, Bassuk AG, Tsang SH, Mahajan VB. PROGRESSION OF SCOTOPIC SINGLE-FLASH ELECTRORETINOGRAPHY IN THE STAGES OF CAPN5 VITREORETINOPATHY. Retinal Cases & Brief Reports. PMID 30300311 DOI: 10.1097/ICB.0000000000000828  0.44
2018 Velez G, Tang PH, Cabral T, Cho GY, Machlab DA, Tsang SH, Bassuk AG, Mahajan VB. Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease. Translational Vision Science & Technology. 7: 12. PMID 30271679 DOI: 10.1167/tvst.7.5.12  0.44
2018 Jauregui R, Park KS, Duong JK, Mahajan VB, Tsang SH. Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography. Scientific Reports. 8: 13130. PMID 30177829 DOI: 10.1038/s41598-018-31488-1  0.44
2018 Takahashi VKL, Takiuti JT, Jauregui R, Lima LH, Tsang SH. Structural disease progression in PDE6-associated autosomal recessive retinitis pigmentosa. Ophthalmic Genetics. 1-5. PMID 30153077 DOI: 10.1080/13816810.2018.1509354  0.4
2018 Liu KY, Sengillo JD, Velez G, Jauregui R, Sakai LY, Maumenee IH, Bassuk AG, Mahajan VB, Tsang SH. Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity. Orphanet Journal of Rare Diseases. 13: 138. PMID 30111362 DOI: 10.1186/s13023-018-0885-4  0.52
2018 Takahashi VKL, Takiuti JT, Jauregui R, Mahajan VB, Tsang SH. Rates of Bone Spicule Pigment Appearance in patients with Retinitis Pigmentosa Sine Pigmento. American Journal of Ophthalmology. PMID 30081015 DOI: 10.1016/j.ajo.2018.07.036  0.44
2018 Lee W, Zernant J, Nagasaki T, Tsang SH, Allikmets R. Deep Scleral Exposure: A Degenerative Outcome of End-Stage Stargardt Disease. American Journal of Ophthalmology. PMID 30055151 DOI: 10.1016/j.ajo.2018.07.018  0.32
2018 Jauregui R, Park KS, Duong JK, Sparrow JR, Tsang SH. Quantitative comparison of near-infrared versus short-wave autofluorescence imaging in monitoring progression of retinitis pigmentosa. American Journal of Ophthalmology. PMID 30053465 DOI: 10.1016/j.ajo.2018.07.012  0.44
2018 Sengillo JD, Fridman G, Cho GY, Buchovecky C, Tsang SH. Novel Mutation in Retinitis Pigmentosa GTPase Regulator Gene Causes Primary Ciliary Dyskinesia and Retinitis Pigmentosa. Ophthalmic Surgery, Lasers & Imaging Retina. 49: 548-552. PMID 30021045 DOI: 10.3928/23258160-20180628-14  0.52
2018 DeNaro BB, Dhrami-Gavazi E, Rubaltelli DM, Freund KB, Lee W, Yannuzzi LA, Tsang SH, Kang JJ. CHORIORETINAL CHANGES IN A GENETICALLY CONFIRMED CASE OF BOUCHER-NEUHÄUSER SYNDROME. Retinal Cases & Brief Reports. PMID 30015775 DOI: 10.1097/ICB.0000000000000769  0.4
2018 Zhang L, Cui X, Jauregui R, Park KS, Justus S, Tsai YT, Duong JK, Hsu CW, Wu WH, Xu CL, Lin CS, Tsang SH. Genetic Rescue Reverses Microglial Activation in Preclinical Models of Retinitis Pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30001913 DOI: 10.1016/j.ymthe.2018.06.014  0.6
2018 Wert KJ, Velez G, Cross MR, Wagner BA, Teoh-Fitzgerald ML, Buettner GR, McAnany J, Olivier A, Tsang SH, Harper MM, Domann FE, Bassuk AG, Mahajan VB. Extracellular superoxide dismutase 3 (SOD3) regulates oxidative stress at the vitreoretinal interface. Free Radical Biology & Medicine. PMID 29940351 DOI: 10.1016/j.freeradbiomed.2018.06.024  0.44
2018 Xu CL, Cho GY, Sengillo JD, Park KS, Mahajan VB, Tsang SH. Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases. Frontiers in Cell and Developmental Biology. 6: 46. PMID 29876348 DOI: 10.3389/fcell.2018.00046  0.52
2018 DiCarlo JE, Mahajan VB, Tsang SH. Gene therapy and genome surgery in the retina. The Journal of Clinical Investigation. 128: 2177-2188. PMID 29856367 DOI: 10.1172/JCI120429  0.44
2018 Zernant J, Lee W, Nagasaki T, Collison FT, Fishman GA, Bertelsen M, Rosenberg T, Gouras P, Tsang SH, Allikmets R. Extremely hypomorphic and severe deep intronic variants in the ABCA4 locus result in varying Stargardt disease phenotypes. Cold Spring Harbor Molecular Case Studies. PMID 29848554 DOI: 10.1101/mcs.a002733  0.32
2018 White EC, Sengillo JD, Cho GY, Bakhoum MF, Tsang SH. Congenital grouped albinotic spots of the retinal pigment epithelium in a patient with hemihypertrophy and café au lait spots. Documenta Ophthalmologica. Advances in Ophthalmology. PMID 29770905 DOI: 10.1007/s10633-018-9639-9  0.52
2018 Jauregui R, Park KS, Bassuk AG, Mahajan VB, Tsang SH. Deferoxamine-induced electronegative ERG responses. Documenta Ophthalmologica. Advances in Ophthalmology. PMID 29770904 DOI: 10.1007/s10633-018-9640-3  0.44
2018 Tsai YT, Wu WH, Lee TT, Wu WP, Xu CL, Park KS, Cui X, Justus S, Lin CS, Jauregui R, Su PY, Tsang SH. Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa. Ophthalmology. PMID 29759820 DOI: 10.1016/j.ophtha.2018.04.001  0.6
2018 Cho GY, Schaefer KA, Bassuk AG, Tsang SH, Mahajan VB. CRISPR GENOME SURGERY IN THE RETINA IN LIGHT OF OFF-TARGETING. Retina (Philadelphia, Pa.). PMID 29746416 DOI: 10.1097/IAE.0000000000002197  0.44
2018 Lin MK, Yang J, Hsu CW, Gore A, Bassuk AG, Brown LM, Colligan R, Sengillo JD, Mahajan VB, Tsang SH. HTRA1, an age-related macular degeneration protease, processes extracellular matrix proteins EFEMP1 and TSP1. Aging Cell. e12710. PMID 29730901 DOI: 10.1111/acel.12710  0.6
2018 Koch SF, Tsang SH. Success of Gene Therapy in Late-Stage Treatment. Advances in Experimental Medicine and Biology. 1074: 101-107. PMID 29721933 DOI: 10.1007/978-3-319-75402-4_13  1
2018 Evans LP, Newell EA, Mahajan M, Tsang SH, Ferguson PJ, Mahoney J, Hue CD, Vogel EW, Morrison B, Arancio O, Nichols R, Bassuk AG, Mahajan VB. Acute vitreoretinal trauma and inflammation after traumatic brain injury in mice. Annals of Clinical and Translational Neurology. 5: 240-251. PMID 29560370 DOI: 10.1002/acn3.523  0.44
2018 Sengillo JD, Lee W, Nagasaki T, Schuerch K, Yannuzzi LA, Freund KB, Sparrow J, Allikmets R, Tsang SH. A Distinct Phenotype of Eyes Shut Homolog (EYS)-Retinitis Pigmentosa is Associated with Variants Near the C-Terminus. American Journal of Ophthalmology. PMID 29550188 DOI: 10.1016/j.ajo.2018.03.008  0.52
2018 Jauregui R, Cho GY, Takahashi VKL, Takiuti JT, Bassuk AG, Mahajan VB, Tsang SH. Caring for Hereditary Childhood Retinal Blindness. Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.). PMID 29536675 DOI: 10.22608/APO.201851  0.44
2018 Velez G, Bassuk AG, Schaefer KA, Brooks B, Gakhar L, Mahajan M, Kahn P, Tsang SH, Ferguson PJ, Mahajan VB. A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay. Cold Spring Harbor Molecular Case Studies. PMID 29472286 DOI: 10.1101/mcs.a002519  0.44
2018 Velez G, Machlab DA, Tang PH, Sun Y, Tsang SH, Bassuk AG, Mahajan VB. Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases. Plos One. 13: e0193250. PMID 29466423 DOI: 10.1371/journal.pone.0193250  0.44
2018 Sengillo JD, Lee W, Bilancia CG, Jobanputra V, Tsang SH. Phenotypic expansion and progression of SPATA7-associated retinitis pigmentosa. Documenta Ophthalmologica. Advances in Ophthalmology. PMID 29411205 DOI: 10.1007/s10633-018-9626-1  0.52
2018 Bakhoum MF, Wu WP, White EC, Sengillo JD, Sanfilippo C, Morcos MM, Freund KB, Perry HD, Sarraf D, Tsang SH. Mitochondrial A3243G mutation results in corneal endothelial polymegathism. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 29376197 DOI: 10.1007/s00417-018-3914-z  0.52
2018 Apatoff MBL, Sengillo JD, White EC, Bakhoum MF, Bassuk AG, Mahajan VB, Tsang SH. Autologous stem cell therapy for inherited and acquired retinal disease. Regenerative Medicine. PMID 29360008 DOI: 10.2217/rme-2017-0089  0.52
2018 Wu WH, Tsai YT, Justus S, Cho GY, Sengillo JD, Xu Y, Cabral T, Lin CS, Bassuk AG, Mahajan VB, Tsang SH. CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology. Methods in Molecular Biology (Clifton, N.J.). 1715: 191-205. PMID 29188514 DOI: 10.1007/978-1-4939-7522-8_13  0.6
2017 Velez G, Bassuk AG, Colgan D, Tsang SH, Mahajan VB. Therapeutic drug repositioning using personalized proteomics of liquid biopsies. Jci Insight. 2. PMID 29263305 DOI: 10.1172/jci.insight.97818  0.44
2017 Chan L, Mahajan VB, Tsang SH. 
Genome Surgery and Gene Therapy in Retinal Disorders. The Yale Journal of Biology and Medicine. 90: 523-532. PMID 29259518  0.68
2017 Roybal CN, Velez G, Toral M, Tsang SH, Bassuk AG, Mahajan VB. Personalized proteomics in proliferative vitreoretinopathy implicate hematopoietic cell recruitment and mTOR as a therapeutic target. American Journal of Ophthalmology. PMID 29246578 DOI: 10.1016/j.ajo.2017.11.025  0.44
2017 Bakhoum MF, Sengillo JD, Cui X, Tsang SH. AUTOIMMUNE RETINOPATHY IN A PATIENT WITH A MISSENSE MUTATION IN PITPNM3. Retinal Cases & Brief Reports. PMID 29176531 DOI: 10.1097/ICB.0000000000000673  0.52
2017 Velez G, Tsang SH, Tsai YT, Hsu CW, Gore A, Abdelhakim AH, Mahajan M, Silverman RH, Sparrow JR, Bassuk AG, Mahajan VB. Gene Therapy Restores Mfrp and Corrects Axial Eye Length. Scientific Reports. 7: 16151. PMID 29170418 DOI: 10.1038/s41598-017-16275-8  0.6
2017 Schaefer K, Mahajan M, Gore A, Tsang SH, Bassuk AG, Mahajan VB. Calpain-5 gene expression in the mouse eye and brain. Bmc Research Notes. 10: 602. PMID 29157313 DOI: 10.1186/s13104-017-2927-8  0.44
2017 Cabral T, Toral MA, Velez G, DiCarlo JE, Gore AM, Mahajan M, Tsang SH, Bassuk AG, Mahajan VB. Dissection of Human Retina and RPE-Choroid for Proteomic Analysis. Journal of Visualized Experiments : Jove. PMID 29155757 DOI: 10.3791/56203  0.44
2017 Cho GY, Justus S, Sengillo JD, Tsang SH. CRISPR in the Retina: Evaluation of Future Potential. Advances in Experimental Medicine and Biology. 1016: 147-155. PMID 29130158 DOI: 10.1007/978-3-319-63904-8_8  0.52
2017 Boudreault K, Schuerch K, Zhao J, Lee W, Cabral T, Yannuzzi LA, Tsang SH, Sparrow JR. Quantitative Autofluorescence Intensities in Acute Zonal Occult Outer Retinopathy vs Healthy Eyes. Jama Ophthalmology. PMID 29075777 DOI: 10.1001/jamaophthalmol.2017.4499  0.4
2017 Li Y, Zhang Y, Xu Y, Kittredge A, Ward N, Chen S, Tsang SH, Yang T. Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca(2+)-dependent Cl(-) currents in human RPE. Elife. 6. PMID 29063836 DOI: 10.7554/eLife.29914  0.68
2017 Sengillo JD, Lee W, Bakhoum MF, Cho GY, Chiang JP, Tsang SH. CHOROIDEREMIA ASSOCIATED WITH A NOVEL SYNONYMOUS MUTATION IN GENE ENCODING REP-1. Retinal Cases & Brief Reports. PMID 29045269 DOI: 10.1097/ICB.0000000000000647  0.52
2017 Cho GY, Abdulla Y, Sengillo JD, Justus S, Schaefer KA, Bassuk AG, Tsang SH, Mahajan VB. CRISPR-mediated Ophthalmic Genome Surgery. Current Ophthalmology Reports. 5: 199-206. PMID 28966884 DOI: 10.1007/s40135-017-0144-1  0.52
2017 Sengillo JD, Cabral T, Schuerch K, Duong J, Lee W, Boudreault K, Xu Y, Justus S, Sparrow JR, Mahajan VB, Tsang SH. Electroretinography Reveals Difference in Cone Function between Syndromic and Nonsyndromic USH2A Patients. Scientific Reports. 7: 11170. PMID 28894305 DOI: 10.1038/s41598-017-11679-y  0.52
2017 Cabral T, Sengillo JD, Duong JK, Justus S, Boudreault K, Schuerch K, Belfort R, Mahajan VB, Sparrow JR, Tsang SH. Retrospective Analysis of Structural Disease Progression in Retinitis Pigmentosa Utilizing Multimodal Imaging. Scientific Reports. 7: 10347. PMID 28871101 DOI: 10.1038/s41598-017-10473-0  0.52
2017 Velez G, Roybal CN, Binkley E, Bassuk AG, Tsang SH, Mahajan VB. Proteomic Analysis of Elevated Intraocular Pressure with Retinal Detachment. American Journal of Ophthalmology Case Reports. 5: 107-110. PMID 28825049 DOI: 10.1016/j.ajoc.2016.12.023  0.44
2017 Boudreault K, Justus S, Sengillo JD, Schuerch K, Lee W, Cabral T, Tsang SH. Efficacy of rituximab in non-paraneoplastic autoimmune retinopathy. Orphanet Journal of Rare Diseases. 12: 129. PMID 28709429 DOI: 10.1186/s13023-017-0680-7  0.52
2017 DiCarlo JE, Sengillo JD, Justus S, Cabral T, Tsang SH, Mahajan VB. CRISPR-Cas Genome Surgery in Ophthalmology. Translational Vision Science & Technology. 6: 13. PMID 28573077 DOI: 10.1167/tvst.6.3.13  0.52
2017 Schaefer KA, Wu WH, Colgan DF, Tsang SH, Bassuk AG, Mahajan VB. Unexpected mutations after CRISPR-Cas9 editing in vivo. Nature Methods. 14: 547-548. PMID 28557981 DOI: 10.1038/nmeth.4293  0.44
2017 Toral MA, Velez G, Boudreault K, Schaefer KA, Xu Y, Saffra N, Bassuk AG, Tsang SH, Mahajan VB. Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia. Molecular Genetics & Genomic Medicine. 5: 202-209. PMID 28546991 DOI: 10.1002/mgg3.266  0.44
2017 Garg A, Lee W, Sengillo JD, Allikmets R, Garg K, Tsang SH. Peripapillary sparing in RDH12-associated Leber congenital amaurosis. Ophthalmic Genetics. 1-5. PMID 28513254 DOI: 10.1080/13816810.2017.1323339  0.52
2017 Koch SF, Duong JK, Hsu CW, Tsai YT, Lin CS, Wahl-Schott CA, Tsang SH. Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. PMID 28468800 DOI: 10.1073/pnas.1615394114  1
2017 Garg A, Yang J, Lee W, Tsang SH. Stem Cell Therapies in Retinal Disorders. Cells. 6. PMID 28157165 DOI: 10.3390/cells6010004  0.44
2017 Cabral T, DiCarlo JE, Justus S, Sengillo JD, Xu Y, Tsang SH. CRISPR applications in ophthalmologic genome surgery. Current Opinion in Ophthalmology. PMID 28141764 DOI: 10.1097/ICU.0000000000000359  0.52
2017 Sengillo JD, Justus S, Cabral T, Tsang SH. Correction of Monogenic and Common Retinal Disorders with Gene Therapy. Genes. 8. PMID 28134823 DOI: 10.3390/genes8020053  0.52
2016 Sengillo JD, Justus S, Tsai YT, Cabral T, Tsang SH. Gene and cell-based therapies for inherited retinal disorders: An update. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 27862925 DOI: 10.1002/ajmg.c.31534  0.52
2016 Zhang L, Du J, Justus S, Hsu CW, Bonet-Ponce L, Wu WH, Tsai YT, Wu WP, Jia Y, Duong JK, Mahajan VB, Lin CS, Wang S, Hurley JB, Tsang SH. Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. The Journal of Clinical Investigation. 126: 4659-4673. PMID 27841758 DOI: 10.1172/JCI86905  0.6
2016 Zhang L, Justus S, Xu Y, Pluchenik T, Hsu CW, Yang J, Duong JK, Lin CS, Jia Y, Bassuk AG, Mahajan VB, Tsang SH. Reprogramming toward anabolism impedes degeneration in a preclinical model of retinitis pigmentosa. Human Molecular Genetics. PMID 27516389 DOI: 10.1093/hmg/ddw256  0.6
2016 Yang J, Bassuk AG, Merl-Pham J, Hsu CW, Colgan DF, Li X, Au KS, Zhang L, Smemo S, Justus S, Nagahama Y, Grossbach AJ, Howard MA, Kawasaki H, Feldstein NA, ... ... Tsang SH, et al. Catenin delta-1 (CTNND1) phosphorylation controls the mesenchymal to epithelial transition in astrocytic tumors. Human Molecular Genetics. PMID 27516388 DOI: 10.1093/hmg/ddw253  0.6
2016 Gakhar L, Bassuk AG, Velez G, Khan S, Yang J, Tsang SH, Mahajan VB. Small-angle x-ray scattering of calpain-5 reveals a highly open conformation among calpains. Journal of Structural Biology. PMID 27474374 DOI: 10.1016/j.jsb.2016.07.017  0.44
2016 Cham A, Bansal M, Banda HK, Kwon Y, Tlucek PS, Bassuk AG, Tsang SH, Sobol WM, Folk JC, Yeh S, Mahajan VB. Secondary glaucoma in CAPN5-associated neovascular inflammatory vitreoretinopathy. Clinical Ophthalmology (Auckland, N.Z.). 10: 1187-97. PMID 27390515 DOI: 10.2147/OPTH.S103324  0.44
2016 Grillo LM, Nguyen HV, Tsang SH, Hood DC, Odel JG. Cobalt-Chromium Metallosis With Normal Electroretinogram. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. PMID 27295601 DOI: 10.1097/WNO.0000000000000400  0.68
2016 Wu WH, Tsai YT, Justus S, Lee T, Zhang L, Lin CS, Bassuk AG, Mahajan VB, Tsang SH. CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27203441 DOI: 10.1038/mt.2016.107  0.6
2016 Wert KJ, Mahajan VB, Zhang L, Yan Y, Li Y, Tosi J, Hsu CW, Nagasaki T, Janisch KM, Grant MB, Mahajan M, Bassuk AG, Tsang SH. Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy. Signal Transduction and Targeted Therapy. 1. PMID 27195131 DOI: 10.1038/sigtrans.2016.5  0.68
2016 Moshfegh Y, Velez G, Li Y, Bassuk AG, Mahajan VB, Tsang SH. BESTROPHIN1 mutations cause defective chloride conductance in patient stem cell-derived RPE. Human Molecular Genetics. PMID 27193166 DOI: 10.1093/hmg/ddw126  0.68
2016 Schaefer KA, Toral MA, Velez G, Cox AJ, Baker SA, Borcherding NC, Colgan DF, Bondada V, Mashburn CB, Yu CG, Geddes JW, Tsang SH, Bassuk AG, Mahajan VB. Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses. Investigative Ophthalmology & Visual Science. 57: 2509-2521. PMID 27152965 DOI: 10.1167/iovs.15-18680  0.44
2016 Boudreault K, Justus S, Lee W, Mahajan VB, Tsang SH. Complication of Autologous Stem Cell Transplantation in Retinitis Pigmentosa. Jama Ophthalmology. PMID 27149677 DOI: 10.1001/jamaophthalmol.2016.0803  0.44
2016 Zheng A, Chin EK, Almeida DR, Tsang SH, Mahajan VB. COMBINED VITRECTOMY AND INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT. Retina (Philadelphia, Pa.). PMID 27148836 DOI: 10.1097/IAE.0000000000001063  0.44
2016 Zhang L, Zheng A, Nie H, Bhavsar KV, Xu Y, Sliney DH, Trokel SL, Tsang SH. Laser-Induced Photic Injury Phenocopies Macular Dystrophy. Ophthalmic Genetics. 37: 59-67. PMID 26927809 DOI: 10.3109/13816810.2015.1059458  0.32
2016 Velez G, Roybal CN, Colgan D, Tsang SH, Bassuk AG, Mahajan VB. Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease. Jama Ophthalmology. PMID 26848019 DOI: 10.1001/jamaophthalmol.2015.5934  0.44
2016 Bassuk AG, Zheng A, Li Y, Tsang SH, Mahajan VB. Precision Medicine: Genetic Repair of Retinitis Pigmentosa in Patient-Derived Stem Cells. Scientific Reports. 6: 19969. PMID 26814166 DOI: 10.1038/srep19969  0.68
2016 Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrústegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB. Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina. The Journal of Biological Chemistry. 291: 4698-710. PMID 26677218 DOI: 10.1074/jbc.M115.698985  0.68
2016 Li Y, Chan L, Nguyen HV, Tsang SH. Personalized Medicine: Cell and Gene Therapy Based on Patient-Specific iPSC-Derived Retinal Pigment Epithelium Cells. Advances in Experimental Medicine and Biology. 854: 549-55. PMID 26427458 DOI: 10.1007/978-3-319-17121-0_73  0.68
2015 Lin MK, Kim SH, Zhang L, Tsai YT, Tsang SH. Rod metabolic demand drives progression in retinopathies. Taiwan Journal of Ophthalmology. 5: 105-108. PMID 29018679 DOI: 10.1016/j.tjo.2015.06.002  0.44
2015 Duncker T, Stein GE, Lee W, Tsang SH, Zernant J, Bearelly S, Hood DC, Greenstein VC, Delori FC, Allikmets R, Sparrow JR. Quantitative Fundus Autofluorescence and Optical Coherence Tomography in ABCA4 Carriers. Investigative Ophthalmology & Visual Science. 56: 7274-85. PMID 26551331 DOI: 10.1167/iovs.15-17371  0.68
2015 Lin MK, Tsai YT, Tsang SH. Emerging Treatments for Retinitis Pigmentosa: Genes and stem cells, as well as new electronic and medical therapies, are gaining ground. Retinal Physician. 12: 52-70. PMID 26503895  0.44
2015 Yang T, Justus S, Li Y, Tsang SH. BEST1: the best target for gene and cell therapies. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26388462 DOI: 10.1038/mt.2015.177  0.68
2015 Koch SF, Tsai YT, Duong JK, Wu WH, Hsu CW, Wu WP, Bonet-Ponce L, Lin CS, Tsang SH. Halting progressive neurodegeneration in advanced retinitis pigmentosa. The Journal of Clinical Investigation. 125: 3704-13. PMID 26301813 DOI: 10.1172/JCI82462  0.68
2015 Nguyen HV, Li Y, Tsang SH. Patient-Specific iPSC-Derived RPE for Modeling of Retinal Diseases. Journal of Clinical Medicine. 4: 567-78. PMID 26239347 DOI: 10.3390/jcm4040567  0.68
2015 Sujirakul T, Lin MK, Duong J, Wei Y, Lopez-Pintado S, Tsang SH. Multimodal Imaging of Central Retinal Disease Progression in a 2-Year Mean Follow-up of Retinitis Pigmentosa. American Journal of Ophthalmology. 160: 786-798.e4. PMID 26164827 DOI: 10.1016/j.ajo.2015.06.032  0.68
2015 Li Y, Nguyen HV, Tsang SH. Skin Biopsy and Patient-Specific Stem Cell Lines. Methods in Molecular Biology (Clifton, N.J.). PMID 26141312 DOI: 10.1007/7651_2015_225  0.44
2015 Gelman R, Tsang SH. SEQUENTIAL CENTRAL RETINAL VEIN AND OPHTHALMIC ARTERY OCCLUSIONS IN A PEDIATRIC CASE OF PRIMARY ANTIPHOSPHOLIPID SYNDROME. Retinal Cases & Brief Reports. PMID 26110520 DOI: 10.1097/ICB.0000000000000161  0.68
2015 Duncker T, Tsang SH, Woods RL, Lee W, Zernant J, Allikmets R, Delori FC, Sparrow JR. Quantitative Fundus Autofluorescence and Optical Coherence Tomography in PRPH2/RDS- and ABCA4-Associated Disease Exhibiting Phenotypic Overlap. Investigative Ophthalmology & Visual Science. 56: 3159-70. PMID 26024099 DOI: 10.1167/iovs.14-16343  0.68
2015 Wert KJ, Bassuk AG, Wu WH, Gakhar L, Coglan D, Mahajan M, Wu S, Yang J, Lin CS, Tsang SH, Mahajan VB. CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model. Human Molecular Genetics. 24: 4584-98. PMID 25994508 DOI: 10.1093/hmg/ddv189  0.6
2015 Bassuk AG, Yeh S, Wu S, Martin DF, Tsang SH, Gakhar L, Mahajan VB. Structural modeling of a novel CAPN5 mutation that causes uveitis and neovascular retinal detachment. Plos One. 10: e0122352. PMID 25856303 DOI: 10.1371/journal.pone.0122352  0.44
2015 Zhang L, Reyes R, Lee W, Chen CL, Chan L, Sujirakul T, Chang S, Tsang SH. Rapid resolution of retinoschisis with acetazolamide. Documenta Ophthalmologica. Advances in Ophthalmology. 131: 63-70. PMID 25796216 DOI: 10.1007/s10633-015-9496-8  0.68
2015 Zheng A, Li Y, Tsang SH. Personalized therapeutic strategies for patients with retinitis pigmentosa. Expert Opinion On Biological Therapy. 15: 391-402. PMID 25613576 DOI: 10.1517/14712598.2015.1006192  0.68
2015 Fung AT, Yzer S, Goldberg N, Wang H, Nissen M, Giovannini A, Merriam JE, Bukanova EN, Cai C, Yannuzzi LA, Tsang SH, Allikmets R. New best1 mutations in autosomal recessive bestrophinopathy. Retina (Philadelphia, Pa.). 35: 773-82. PMID 25545482 DOI: 10.1097/IAE.0000000000000387  0.4
2015 Greenstein VC, Amaro-Quireza L, Abraham ES, Ramachandran R, Tsang SH, Hood DC. A comparison of structural and functional changes in patients screened for hydroxychloroquine retinopathy. Documenta Ophthalmologica. Advances in Ophthalmology. 130: 13-23. PMID 25502494 DOI: 10.1007/s10633-014-9474-6  0.68
2015 Marsiglia M, Lee W, Mahajan VB, Zernant J, Delori FC, Tsang SH, Sparrow JR. Quantitative autofluorescence as a clinical tool for expedited differential diagnosis of retinal degeneration. Jama Ophthalmology. 133: 219-20. PMID 25375877 DOI: 10.1001/jamaophthalmol.2014.4507  0.44
2015 Duncker T, Tsang SH, Lee W, Zernant J, Allikmets R, Delori FC, Sparrow JR. Quantitative fundus autofluorescence distinguishes ABCA4-associated and non-ABCA4-associated bull's-eye maculopathy. Ophthalmology. 122: 345-55. PMID 25283059 DOI: 10.1016/j.ophtha.2014.08.017  0.68
2015 Sujirakul T, Davis R, Erol D, Zhang L, Schillizzi G, Royo-Dujardin L, Shen S, Tsang S. Bilateral Concordance of the Fundus Hyperautofluorescent Ring in Typical Retinitis Pigmentosa Patients. Ophthalmic Genetics. 36: 113-22. PMID 24111858 DOI: 10.3109/13816810.2013.841962  0.68
2015 Sparrow JR, Marsiglia M, Allikmets R, Tsang S, Lee W, Duncker T, Zernant J. Flecks in recessive stargardt disease: Short-wavelength autofluorescence, near-infrared autofluorescence, and optical coherence tomography Investigative Ophthalmology and Visual Science. 56: 5029-5039. DOI: 10.1167/iovs.15-16763  0.68
2015 Wert KJ, Bassuk AG, Wu WH, Gakhar L, Coglan D, Mahajan M, Wu S, Yang J, Lin CS, Tsang SH, Mahajan VB. CAPN5 mutation in hereditary uveitis: The R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model Human Molecular Genetics. 24: 4584-4598. DOI: 10.1093/hmg/ddv189  0.68
2015 Lin MK, Kim SH, Zhang L, Tsai YT, Tsang SH. Rod metabolic demand drives progression in retinopathies Taiwan Journal of Ophthalmology. 5: 105-108. DOI: 10.1016/j.tjo.2015.06.002  0.68
2014 Barrett D, Yang J, Sujirakul T, Tsang SH. Vigabatrin Retinal Toxicity First Detected with Electroretinographic Changes: A Case Report. Journal of Clinical & Experimental Ophthalmology. 5. PMID 26295007 DOI: 10.4172/2155-9570.1000363  0.44
2014 Tsang SH, Chan L, Tsai YT, Wu WH, Hsu CW, Yang J, Tosi J, Wert KJ, Davis RJ, Mahajan VB. Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis). Transactions of the American Ophthalmological Society. 112: 103-15. PMID 25646031  0.68
2014 Gelman R, Greenberg JP, Duncker T, Nguyen HV, Yannuzzi LA, Tsang SH. Hyperautofluorescent macular ring in a series of patients with enhanced S-cone syndrome. Ophthalmic Surgery, Lasers & Imaging Retina. 45: 592-5. PMID 25423642 DOI: 10.3928/23258160-20141118-17  0.68
2014 Chen J, Ingham N, Kelly J, Jadeja S, Goulding D, Pass J, Mahajan VB, Tsang SH, Nijnik A, Jackson IJ, White JK, Forge A, Jagger D, Steel KP. Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. Plos Genetics. 10: e1004688. PMID 25356849 DOI: 10.1371/journal.pgen.1004688  0.44
2014 Duncker T, Marsiglia M, Lee W, Zernant J, Tsang SH, Allikmets R, Greenstein VC, Sparrow JR. Correlations among near-infrared and short-wavelength autofluorescence and spectral-domain optical coherence tomography in recessive Stargardt disease. Investigative Ophthalmology & Visual Science. 55: 8134-43. PMID 25342616 DOI: 10.1167/iovs.14-14848  0.68
2014 Nõupuu K, Lee W, Zernant J, Tsang SH, Allikmets R. Structural and genetic assessment of the ABCA4-associated optical gap phenotype. Investigative Ophthalmology & Visual Science. 55: 7217-26. PMID 25301883 DOI: 10.1167/iovs.14-14674  0.68
2014 Park SP, Lee W, Bae EJ, Greenstein V, Sin BH, Chang S, Tsang SH. Early structural anomalies observed by high-resolution imaging in two related cases of autosomal-dominant retinitis pigmentosa. Ophthalmic Surgery, Lasers & Imaging Retina. 45: 469-473. PMID 25215869 DOI: 10.3928/23258160-20140908-01  0.68
2014 Lee W, Nõupuu K, Oll M, Duncker T, Burke T, Zernant J, Bearelly S, Tsang SH, Sparrow JR, Allikmets R. The external limiting membrane in early-onset Stargardt disease. Investigative Ophthalmology & Visual Science. 55: 6139-49. PMID 25139735 DOI: 10.1167/iovs.14-15126  0.68
2014 Zernant J, Collison FT, Lee W, Fishman GA, Noupuu K, Yuan B, Cai C, Lupski JR, Yannuzzi LA, Tsang SH, Allikmets R. Genetic and clinical analysis of ABCA4-associated disease in African American patients. Human Mutation. 35: 1187-94. PMID 25066811 DOI: 10.1002/humu.22626  0.4
2014 Li Y, Wu WH, Hsu CW, Nguyen HV, Tsai YT, Chan L, Nagasaki T, Maumenee IH, Yannuzzi LA, Hoang QV, Hua H, Egli D, Tsang SH. Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1688-97. PMID 24895994 DOI: 10.1038/mt.2014.100  0.68
2014 Shen S, Sujirakul T, Tsang SH. Next-generation sequencing revealed a novel mutation in the gene encoding the beta subunit of rod phosphodiesterase. Ophthalmic Genetics. 35: 142-50. PMID 24828262 DOI: 10.3109/13816810.2014.915328  0.68
2014 Tsang SH, Burke T, Oll M, Yzer S, Lee W, Xie YA, Allikmets R. Whole exome sequencing identifies CRB1 defect in an unusual maculopathy phenotype. Ophthalmology. 121: 1773-82. PMID 24811962 DOI: 10.1016/j.ophtha.2014.03.010  0.68
2014 North V, Gelman R, Tsang SH. Juvenile-onset macular degeneration and allied disorders. Developments in Ophthalmology. 53: 44-52. PMID 24732760 DOI: 10.1159/000357293  0.68
2014 Wert KJ, Lin JH, Tsang SH. General pathophysiology in retinal degeneration. Developments in Ophthalmology. 53: 33-43. PMID 24732759 DOI: 10.1159/000357294  0.68
2014 Burke TR, Duncker T, Woods RL, Greenberg JP, Zernant J, Tsang SH, Smith RT, Allikmets R, Sparrow JR, Delori FC. Quantitative fundus autofluorescence in recessive Stargardt disease. Investigative Ophthalmology & Visual Science. 55: 2841-52. PMID 24677105 DOI: 10.1167/iovs.13-13624  0.68
2014 Duncker T, Greenberg JP, Ramachandran R, Hood DC, Smith RT, Hirose T, Woods RL, Tsang SH, Delori FC, Sparrow JR. Quantitative fundus autofluorescence and optical coherence tomography in best vitelliform macular dystrophy. Investigative Ophthalmology & Visual Science. 55: 1471-82. PMID 24526438 DOI: 10.1167/iovs.13-13834  0.68
2014 Greenberg JP, Sherman J, Zweifel SA, Chen RW, Duncker T, Kohl S, Baumann B, Wissinger B, Yannuzzi LA, Tsang SH. Spectral-domain optical coherence tomography staging and autofluorescence imaging in achromatopsia. Jama Ophthalmology. 132: 437-45. PMID 24504161 DOI: 10.1001/jamaophthalmol.2013.7987  0.68
2014 Yang J, Li Y, Chan L, Tsai YT, Wu WH, Nguyen HV, Hsu CW, Li X, Brown LM, Egli D, Sparrow JR, Tsang SH. Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines. Human Molecular Genetics. 23: 3445-55. PMID 24497574 DOI: 10.1093/hmg/ddu053  0.68
2014 Yang J, Li Y, Erol D, Wu WH, Tsai YT, Li XR, Davis RJ, Tsang SH. Generation of induced pluripotent stem cells from conjunctiva. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 252: 423-31. PMID 24492934 DOI: 10.1007/s00417-014-2575-9  0.68
2014 Bassuk AG, Sujirakul T, Tsang SH, Mahajan VB. A novel RPGR mutation masquerading as Stargardt disease. The British Journal of Ophthalmology. 98: 709-11. PMID 24489377 DOI: 10.1136/bjophthalmol-2013-304822  0.68
2014 Hong IH, Park SP, Chen CL, Kim HK, Tsang SH, Chang S. Cone photoreceptor abnormalities correlate with vision loss in a case of acute posterior multifocal placoid pigment epitheliopathy. Ophthalmic Surgery, Lasers & Imaging Retina. 45: 74-8. PMID 24392917 DOI: 10.3928/23258160-20131220-12  0.68
2014 Wert KJ, Skeie JM, Bassuk AG, Olivier AK, Tsang SH, Mahajan VB. Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina. Human Molecular Genetics. 23: 2665-77. PMID 24381307 DOI: 10.1093/hmg/ddt661  0.68
2014 Nong E, Lee W, Merriam JE, Allikmets R, Tsang SH. Disease progression in autosomal dominant cone-rod dystrophy caused by a novel mutation (D100G) in the GUCA1A gene. Documenta Ophthalmologica. Advances in Ophthalmology. 128: 59-67. PMID 24352742 DOI: 10.1007/s10633-013-9420-z  0.68
2014 Skeie JM, Tsang SH, Zande RV, Fickbohm MM, Shah SS, Vallone JG, Mahajan VB. A biorepository for ophthalmic surgical specimens. Proteomics. Clinical Applications. 8: 209-17. PMID 24115637 DOI: 10.1002/prca.201300043  0.68
2014 Wert KJ, Sancho-Pelluz J, Tsang SH. Mid-stage intervention achieves similar efficacy as conventional early-stage treatment using gene therapy in a pre-clinical model of retinitis pigmentosa. Human Molecular Genetics. 23: 514-23. PMID 24101599 DOI: 10.1093/hmg/ddt452  0.68
2014 Lee TJ, Hwang JC, Chen RW, Lima LH, Wang NK, Tosi J, Freund KB, Yannuzzi LA, Tsang SH. The role of fundus autofluorescence in late-onset retinitis pigmentosa (LORP) diagnosis. Ophthalmic Genetics. 35: 170-9. PMID 23899229 DOI: 10.3109/13816810.2013.800891  0.68
2014 Tsang SH, Chan L, Tsai YT, Wu WH, Hsu CW, Yang J, Tosi J, Wert KJ, Davis RJ, Mahajan VB. Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an American ophthalmological society thesis) Transactions of the American Ophthalmological Society. 112: 103-115.  0.68
2013 Park SP, Siringo FS, Pensec N, Hong IH, Sparrow J, Barile G, Tsang SH, Chang S. Comparison of fundus autofluorescence between fundus camera and confocal scanning laser ophthalmoscope-based systems. Ophthalmic Surgery, Lasers & Imaging Retina. 44: 536-43. PMID 24221461 DOI: 10.3928/23258160-20131105-04  0.68
2013 Barile GR, Garg A, Hood DC, Marr B, Hussein S, Tsang SH. Unilateral retinopathy secondary to occult primary intraocular lymphoma. Documenta Ophthalmologica. Advances in Ophthalmology. 127: 261-9. PMID 24081663 DOI: 10.1007/s10633-013-9409-7  0.68
2013 Garg A, Oll M, Yzer S, Chang S, Barile GR, Merriam JC, Tsang SH, Bearelly S. Reticular pseudodrusen in early age-related macular degeneration are associated with choroidal thinning. Investigative Ophthalmology & Visual Science. 54: 7075-81. PMID 24071958 DOI: 10.1167/iovs.13-12474  0.68
2013 Duncker T, Lee W, Tsang SH, Greenberg JP, Zernant J, Allikmets R, Sparrow JR. Distinct characteristics of inferonasal fundus autofluorescence patterns in stargardt disease and retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 54: 6820-6. PMID 24071957 DOI: 10.1167/iovs.13-12895  0.68
2013 Lenis TL, Dhrami-Gavazi E, Lee W, Mukkamala SK, Tabacaru MR, Yannuzzi L, Gouras P, Tsang SH. Novel compound heterozygous mutations resulting in cone dystrophy with supernormal rod response. Jama Ophthalmology. 131: 1482-5. PMID 24029832 DOI: 10.1001/jamaophthalmol.2013.4681  0.68
2013 Yzer S, Barbazetto I, Allikmets R, van Schooneveld MJ, Bergen A, Tsang SH, Jacobson SG, Yannuzzi LA. Expanded clinical spectrum of enhanced S-cone syndrome. Jama Ophthalmology. 131: 1324-30. PMID 23989059 DOI: 10.1001/jamaophthalmol.2013.4349  0.68
2013 Yang J, Yang FH, Peng CH, Erol D, Tsang SH, Li XR. Surgical treatment of 32 cases of long-term atopic keratoconjunctivitis using the amniotic membrane. Eye (London, England). 27: 1254-62. PMID 23949491 DOI: 10.1038/eye.2013.161  0.68
2013 Davis RJ, Hsu CW, Tsai YT, Wert KJ, Sancho-Pelluz J, Lin CS, Tsang SH. Therapeutic margins in a novel preclinical model of retinitis pigmentosa. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13475-83. PMID 23946405 DOI: 10.1523/JNEUROSCI.0419-13.2013  0.68
2013 White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, ... ... Tsang SH, et al. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell. 154: 452-64. PMID 23870131 DOI: 10.1016/j.cell.2013.06.022  0.68
2013 Wang NK, Lai CC, Liu CH, Yeh LK, Chou CL, Kong J, Nagasaki T, Tsang SH, Chien CL. Origin of fundus hyperautofluorescent spots and their role in retinal degeneration in a mouse model of Goldmann-Favre syndrome. Disease Models & Mechanisms. 6: 1113-22. PMID 23828046 DOI: 10.1242/dmm.012112  0.68
2013 Goldberg NR, Greenberg JP, Laud K, Tsang S, Freund KB. Outer retinal tubulation in degenerative retinal disorders. Retina (Philadelphia, Pa.). 33: 1871-6. PMID 23676993 DOI: 10.1097/IAE.0b013e318296b12f  0.68
2013 Acton JH, Greenberg JP, Greenstein VC, Marsiglia M, Tabacaru M, Theodore Smith R, Tsang SH. Evaluation of multimodal imaging in carriers of X-linked retinitis pigmentosa. Experimental Eye Research. 113: 41-8. PMID 23669302 DOI: 10.1016/j.exer.2013.05.003  0.68
2013 Park SP, Hong IH, Tsang SH, Lee W, Horowitz J, Yzer S, Allikmets R, Chang S. Disruption of the human cone photoreceptor mosaic from a defect in NR2E3 transcription factor function in young adults. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 251: 2299-309. PMID 23604511 DOI: 10.1007/s00417-013-2296-5  0.68
2013 Chen J, Ingham N, Clare S, Raisen C, Vancollie VE, Ismail O, McIntyre RE, Tsang SH, Mahajan VB, Dougan G, Adams DJ, White JK, Steel KP. Mcph1-deficient mice reveal a role for MCPH1 in otitis media. Plos One. 8: e58156. PMID 23516444 DOI: 10.1371/journal.pone.0058156  0.68
2013 Pyo Park S, Hwan Hong I, Tsang SH, Chang S. Cellular imaging demonstrates genetic mosaicism in heterozygous carriers of an X-linked ciliopathy gene. European Journal of Human Genetics : Ejhg. 21: 1240-8. PMID 23443027 DOI: 10.1038/ejhg.2013.21  0.68
2013 Wang NK, Lai CC, Chou CL, Chen YP, Chuang LH, Chao AN, Tseng HJ, Chang CJ, Wu WC, Chen KJ, Tsang SH. Choroidal thickness and biometric markers for the screening of lacquer cracks in patients with high myopia. Plos One. 8: e53660. PMID 23349728 DOI: 10.1371/journal.pone.0053660  0.68
2013 Duncker T, Tabacaru MR, Lee W, Tsang SH, Sparrow JR, Greenstein VC. Comparison of near-infrared and short-wavelength autofluorescence in retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 54: 585-91. PMID 23287793 DOI: 10.1167/iovs.12-11176  0.68
2013 Park SP, Chung JK, Greenstein V, Tsang SH, Chang S. A study of factors affecting the human cone photoreceptor density measured by adaptive optics scanning laser ophthalmoscope. Experimental Eye Research. 108: 1-9. PMID 23276813 DOI: 10.1016/j.exer.2012.12.011  0.68
2013 Wert KJ, Davis RJ, Sancho-Pelluz J, Nishina PM, Tsang SH. Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa. Human Molecular Genetics. 22: 558-67. PMID 23108158 DOI: 10.1093/hmg/dds466  0.68
2013 Burke TR, Yzer S, Zernant J, Smith RT, Tsang SH, Allikmets R. Abnormality in the external limiting membrane in early Stargardt disease. Ophthalmic Genetics. 34: 75-7. PMID 22871184 DOI: 10.3109/13816810.2012.707271  0.68
2013 Yang J, Nong E, Tsang SH. Induced pluripotent stem cells and retinal degeneration treatment Expert Review of Ophthalmology. 8: 5-8. DOI: 10.1586/eop.12.75  0.68
2013 Chen J, Ingham N, Clare S, Raisen C, Vancollie VE, Ismail O, McIntyre RE, Tsang SH, Mahajan VB, Dougan G, Adams DJ, White JK, Steel KP. Correction: Mcph1-deficient mice reveal a role for MCPH1 in otitis media (PLoS ONE) Plos One. 8. DOI: 10.1371/annotation/fadb7426-df05-4ec5-a0ba-21981295b0eb  0.68
2012 Verdina T, Tsang SH, Greenstein VC, Zernant J, Sodi A, Lima LH, Chang S, Allikmets R, Menchini U. Functional Analysis of Retinal Flecks in Stargardt Disease. Journal of Clinical & Experimental Ophthalmology. 3. PMID 24409374 DOI: 10.4172/2155-9570.1000233  0.4
2012 Wert KJ, Skeie JM, Davis RJ, Tsang SH, Mahajan VB. Subretinal injection of gene therapy vectors and stem cells in the perinatal mouse eye. Journal of Visualized Experiments : Jove. PMID 23207897 DOI: 10.3791/4286  0.68
2012 McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F, Ramirez-Solis R, Estabel J, Gallagher FA, ... ... Tsang SH, et al. Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. Plos Genetics. 8: e1003022. PMID 23166506 DOI: 10.1371/journal.pgen.1003022  0.68
2012 Yang J, Naumann MC, Tsai YT, Tosi J, Erol D, Lin CS, Davis RJ, Tsang SH. Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors. Plos One. 7: e43889. PMID 22970106 DOI: 10.1371/journal.pone.0043889  0.68
2012 Li Y, Tsai YT, Hsu CW, Erol D, Yang J, Wu WH, Davis RJ, Egli D, Tsang SH. Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa. Molecular Medicine (Cambridge, Mass.). 18: 1312-9. PMID 22895806 DOI: 10.2119/molmed.2012.00242  0.68
2012 Xie J, Wang GJ, Yow L, Humayun MS, Weiland JD, Cela CJ, Jadvar H, Lazzi G, Dhrami-Gavazi E, Tsang SH. Preservation of retinotopic map in retinal degeneration. Experimental Eye Research. 98: 88-96. PMID 22685713 DOI: 10.1016/j.exer.2012.03.017  0.68
2012 Burke TR, Fishman GA, Zernant J, Schubert C, Tsang SH, Smith RT, Ayyagari R, Koenekoop RK, Umfress A, Ciccarelli ML, Baldi A, Iannaccone A, Cremers FP, Klaver CC, Allikmets R. Retinal phenotypes in patients homozygous for the G1961E mutation in the ABCA4 gene. Investigative Ophthalmology & Visual Science. 53: 4458-67. PMID 22661473 DOI: 10.1167/iovs.11-9166  0.68
2012 Burke TR, Tsang SH, Zernant J, Smith RT, Allikmets R. Familial discordance in Stargardt disease. Molecular Vision. 18: 227-33. PMID 22312191  0.68
2012 Xu L, Burke TR, Greenberg JP, Mahajan VB, Tsang SH. Infrared imaging and optical coherence tomography reveal early-stage astrocytic hamartomas not detectable by fundoscopy. American Journal of Ophthalmology. 153: 883-889.e2. PMID 22310082 DOI: 10.1016/j.ajo.2011.10.033  0.68
2012 Sancho-Pelluz J, Tosi J, Hsu CW, Lee F, Wolpert K, Tabacaru MR, Greenberg JP, Tsang SH, Lin CS. Mice with a D190N mutation in the gene encoding rhodopsin: a model for human autosomal-dominant retinitis pigmentosa. Molecular Medicine (Cambridge, Mass.). 18: 549-55. PMID 22252712 DOI: 10.2119/molmed.2011.00475  0.68
2012 Lima LH, Greenberg JP, Greenstein VC, Smith RT, Sallum JM, Thirkill C, Yannuzzi LA, Tsang SH. Hyperautofluorescent ring in autoimmune retinopathy. Retina (Philadelphia, Pa.). 32: 1385-94. PMID 22218149 DOI: 10.1097/IAE.0b013e3182398107  0.68
2012 Marsiglia M, Duncker T, Peiretti E, Brodie SE, Tsang SH. Unilateral retinitis pigmentosa: a proposal of genetic pathogenic mechanisms. European Journal of Ophthalmology. 22: 654-60. PMID 22139616 DOI: 10.5301/ejo.5000086  0.68
2012 Lima LH, Burke T, Greenstein VC, Chou CL, Cella W, Yannuzzi LA, Tsang SH. Progressive constriction of the hyperautofluorescent ring in retinitis pigmentosa. American Journal of Ophthalmology. 153: 718-27, 727.e1-2. PMID 22137208 DOI: 10.1016/j.ajo.2011.08.043  0.68
2012 Park SP, Chang S, Allikmets R, Smith RT, Burke TR, Gregory-Roberts E, Tsang SH. Disruption in Bruch membrane in patients with Stargardt disease. Ophthalmic Genetics. 33: 49-52. PMID 22060670 DOI: 10.3109/13816810.2011.628358  0.68
2012 Chen RW, Greenberg JP, Lazow MA, Ramachandran R, Lima LH, Hwang JC, Schubert C, Braunstein A, Allikmets R, Tsang SH. Autofluorescence imaging and spectral-domain optical coherence tomography in incomplete congenital stationary night blindness and comparison with retinitis pigmentosa. American Journal of Ophthalmology. 153: 143-54.e2. PMID 21920492 DOI: 10.1016/j.ajo.2011.06.018  0.68
2012 Tsang SH, Woodruff ML, Lin CS, Jacobson BD, Naumann MC, Hsu CW, Davis RJ, Cilluffo MC, Chen J, Fain GL. Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling. Cellular Signalling. 24: 181-8. PMID 21920434 DOI: 10.1016/j.cellsig.2011.08.021  0.68
2012 Greenstein VC, Duncker T, Holopigian K, Carr RE, Greenberg JP, Tsang SH, Hood DC. Structural and functional changes associated with normal and abnormal fundus autofluorescence in patients with retinitis pigmentosa. Retina (Philadelphia, Pa.). 32: 349-57. PMID 21909055 DOI: 10.1097/IAE.0b013e31821dfc17  0.68
2011 Mahajan VB, Skeie JM, Assefnia AH, Mahajan M, Tsang SH. Mouse eye enucleation for remote high-throughput phenotyping. Journal of Visualized Experiments : Jove. PMID 22126835 DOI: 10.3791/3184  0.68
2011 Hood DC, Zhang X, Ramachandran R, Talamini CL, Raza A, Greenberg JP, Sherman J, Tsang SH, Birch DG. The inner segment/outer segment border seen on optical coherence tomography is less intense in patients with diminished cone function. Investigative Ophthalmology & Visual Science. 52: 9703-9. PMID 22110066 DOI: 10.1167/iovs.11-8650  0.68
2011 Zernant J, Schubert C, Im KM, Burke T, Brown CM, Fishman GA, Tsang SH, Gouras P, Dean M, Allikmets R. Analysis of the ABCA4 gene by next-generation sequencing. Investigative Ophthalmology & Visual Science. 52: 8479-87. PMID 21911583 DOI: 10.1167/iovs.11-8182  0.68
2011 Tosi J, Sancho-Pelluz J, Davis RJ, Hsu CW, Wolpert KV, Sengillo JD, Lin CS, Tsang SH. Lentivirus-mediated expression of cDNA and shRNA slows degeneration in retinitis pigmentosa. Experimental Biology and Medicine (Maywood, N.J.). 236: 1211-7. PMID 21885480 DOI: 10.1258/ebm.2011.011053  0.68
2011 Burke TR, Rhee DW, Smith RT, Tsang SH, Allikmets R, Chang S, Lazow MA, Hood DC, Greenstein VC. Quantification of peripapillary sparing and macular involvement in Stargardt disease (STGD1). Investigative Ophthalmology & Visual Science. 52: 8006-15. PMID 21873672 DOI: 10.1167/iovs.11-7693  0.68
2011 Tsang SH, Woodruff ML, Hsu CW, Naumann MC, Cilluffo M, Tosi J, Lin CS. Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo. Cellular Signalling. 23: 1584-9. PMID 21616145 DOI: 10.1016/j.cellsig.2011.05.007  0.68
2011 Burke TR, Tsang SH. Allelic and phenotypic heterogeneity in ABCA4 mutations. Ophthalmic Genetics. 32: 165-74. PMID 21510770 DOI: 10.3109/13816810.2011.565397  0.68
2011 Skeie JM, Tsang SH, Mahajan VB. Evisceration of mouse vitreous and retina for proteomic analyses. Journal of Visualized Experiments : Jove. PMID 21490583 DOI: 10.3791/2795  0.68
2011 Lima LH, Barbazetto IA, Chen R, Yannuzzi LA, Tsang SH, Spaide RF. Macular dystrophy in Heimler syndrome. Ophthalmic Genetics. 32: 97-100. PMID 21366429 DOI: 10.3109/13816810.2010.551797  0.68
2011 Tosi J, Davis RJ, Wang NK, Naumann M, Lin CS, Tsang SH. shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa. Journal of Cellular and Molecular Medicine. 15: 1778-87. PMID 20950332 DOI: 10.1111/j.1582-4934.2010.01201.x  0.68
2011 Gelman R, Tsang SH. Masqueraders of age-related macular degeneration: A number of inherited retinal diseases phenocopy AMD Retina Today. 65-70.  0.68
2010 Wang NK, Chou CL, Tsang SH. Comparing different imaging modalities in harada disease: a case report. Retinal Cases & Brief Reports. 4: 352-5. PMID 25390915 DOI: 10.1097/ICB.0b013e3181b5ee42  0.68
2010 Nan-Kai W, Tosi J, Kasanuki JM, Chou CL, Kong J, Parmalee N, Wert KJ, Allikmets R, Lai CC, Chien CL, Nagasaki T, Lin CS, Tsang SH. Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for Retinitis Pigmentosa: Transplantation 2010 April 27;89 (8): 911-919. Annals of Neurosciences. 17: 185-6. PMID 25205903 DOI: 10.5214/ans.0972.7531.1017408  0.6
2010 Lima LH, Cella W, Brue C, Tsang SH. Unilateral electronegative ERG in a presumed central retinal artery occlusion. Clinical Ophthalmology (Auckland, N.Z.). 4: 1311-4. PMID 21139671 DOI: 10.2147/OPTH.S10374  0.68
2010 Mukkamala K, Gentile RC, Willner J, Tsang S. Choroideremia in a woman with ectodermal dysplasia and complex translocations involving chromosomes X, 1, and 3 Ophthalmic Genetics. 31: 178-182. PMID 21067479 DOI: 10.3109/13816810.2010.497529  0.68
2010 Burke TR, Allikmets R, Smith RT, Gouras P, Tsang SH. Loss of peripapillary sparing in non-group I Stargardt disease. Experimental Eye Research. 91: 592-600. PMID 20696155 DOI: 10.1016/j.exer.2010.07.018  0.68
2010 Braunstein A, Trief D, Wang NK, Chang S, Tsang SH. Vitamin A deficiency in New York City. Lancet. 376: 267. PMID 20663549 DOI: 10.1016/S0140-6736(09)61874-2  0.68
2010 Kim DY, Hwang JC, Moore AT, Bird AC, Tsang SH. Fundus autofluorescence and optical coherence tomography of congenital grouped albinotic spots. Retina (Philadelphia, Pa.). 30: 1217-22. PMID 20539258 DOI: 10.1097/IAE.0b013e3181cea5a5  0.68
2010 Ferrara DC, Costa RA, Tsang S, Calucci D, Jorge R, Freund KB. Multimodal fundus imaging in Best vitelliform macular dystrophy Graefe's Archive For Clinical and Experimental Ophthalmology. 248: 1377-1386. PMID 20414784 DOI: 10.1007/s00417-010-1381-2  0.68
2010 Cella W, Lima LH, Wang NK, Tosi J, Yannuzzi LA, Tsang SH. Autofluorescence and High-Resolution OCT Findings Revealed Ciliopathy in Senior-Loken Syndrome. Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society For Imaging in the Eye. 1-4. PMID 20337316 DOI: 10.3928/15428877-20100215-55  0.6
2010 Hwang JC, Kim DY, Chou CL, Tsang SH. Fundus autofluorescence, optical coherence tomography, and electroretinogram findings in choroidal sclerosis. Retina (Philadelphia, Pa.). 30: 1095-103. PMID 20224472 DOI: 10.1097/IAE.0b013e3181cd48f9  0.68
2010 Wang NK, Tosi J, Kasanuki JM, Chou CL, Kong J, Parmalee N, Wert KJ, Allikmets R, Lai CC, Chien CL, Nagasaki T, Lin CS, Tsang SH. Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa. Transplantation. 89: 911-9. PMID 20164818 DOI: 10.1097/TP.0b013e3181d45a61  0.68
2010 Tosi J, Wang NK, Zhao J, Chou CL, Kasanuki JM, Tsang SH, Nagasaki T. Rapid and noninvasive imaging of retinal ganglion cells in live mouse models of glaucoma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 386-93. PMID 19937134 DOI: 10.1007/s11307-009-0292-2  0.68
2009 Shah SS, Tsang SH, Mahajan VB. Erythropoetin receptor expression in the human diabetic retina. Bmc Research Notes. 2: 234. PMID 19930719 DOI: 10.1186/1756-0500-2-234  0.44
2009 Janisch KM, Kasanuki JM, Naumann MC, Davis RJ, Lin CS, Semple-Rowland S, Tsang SH. Light-dependent phosphorylation of the gamma subunit of cGMP-phophodiesterase (PDE6gamma) at residue threonine 22 in intact photoreceptor neurons. Biochemical and Biophysical Research Communications. 390: 1149-53. PMID 19878658 DOI: 10.1016/j.bbrc.2009.10.106  0.68
2009 Lima LH, Cella W, Greenstein VC, Wang NK, Busuioc M, Smith RT, Yannuzzi LA, Tsang SH. Structural assessment of hyperautofluorescent ring in patients with retinitis pigmentosa. Retina (Philadelphia, Pa.). 29: 1025-31. PMID 19584660 DOI: 10.1097/IAE.0b013e3181ac2418  0.68
2009 Wang NK, Fine HF, Chang S, Chou CL, Cella W, Tosi J, Lin CS, Nagasaki T, Tsang SH. Cellular origin of fundus autofluorescence in patients and mice with a defective NR2E3 gene. The British Journal of Ophthalmology. 93: 1234-40. PMID 19429590 DOI: 10.1136/bjo.2008.153577  0.68
2009 Tosi J, Janisch KM, Wang NK, Kasanuki JM, Flynn JT, Lin CS, Tsang SH. Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. Ophthalmology. 116: 971-80. PMID 19410955 DOI: 10.1016/j.ophtha.2008.10.032  0.68
2009 Tosi J, Tsui I, Lima LH, Wang NK, Tsang SH. Case report: autofluorescence imaging and phenotypic variance in a sibling pair with early-onset retinal dystrophy due to defective CRB1 function. Current Eye Research. 34: 395-400. PMID 19401883 DOI: 10.1080/02713680902859639  0.68
2009 Wang NK, Chou CL, Lima LH, Cella W, Tosi J, Yannuzzi LA, Tsang SH. Fundus autofluorescence in cone dystrophy. Documenta Ophthalmologica. Advances in Ophthalmology. 119: 141-4. PMID 19340470 DOI: 10.1007/s10633-009-9172-y  0.68
2009 Gomes NL, Greenstein VC, Carlson JN, Tsang SH, Smith RT, Carr RE, Hood DC, Chang S. A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease. Investigative Ophthalmology & Visual Science. 50: 3953-9. PMID 19324865 DOI: 10.1167/iovs.08-2657  0.68
2009 Cella W, Greenstein VC, Zernant-Rajang J, Smith TR, Barile G, Allikmets R, Tsang SH. G1961E mutant allele in the Stargardt disease gene ABCA4 causes bull's eye maculopathy. Experimental Eye Research. 89: 16-24. PMID 19217903 DOI: 10.1016/j.exer.2009.02.001  0.4
2008 Airiani S, Cella W, Chou CL, Tosi J, Tsang SH. Benign panretinal uniform radial linear-shaped flecks. Clinical & Experimental Ophthalmology. 36: 891-4. PMID 19278486 DOI: 10.1111/j.1442-9071.2009.01906.x  0.68
2008 Tsui I, Chou CL, Palmer N, Lin CS, Tsang SH. Phenotype-genotype correlations in autosomal dominant retinitis pigmentosa caused by RHO, D190N. Current Eye Research. 33: 1014-22. PMID 19085385 DOI: 10.1080/02713680802484645  0.6
2008 Tsang SH, Tsui I, Chou CL, Zernant J, Haamer E, Iranmanesh R, Tosi J, Allikmets R. A novel mutation and phenotypes in phosphodiesterase 6 deficiency. American Journal of Ophthalmology. 146: 780-8. PMID 18723146 DOI: 10.1016/j.ajo.2008.06.017  0.68
2008 Davis RJ, Tosi J, Janisch KM, Kasanuki JM, Wang NK, Kong J, Tsui I, Cilluffo M, Woodruff ML, Fain GL, Lin CS, Tsang SH. Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q). Investigative Ophthalmology & Visual Science. 49: 5067-76. PMID 18658088 DOI: 10.1167/iovs.07-1422  0.68
2008 Woodruff ML, Janisch KM, Peshenko IV, Dizhoor AM, Tsang SH, Fain GL. Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2064-74. PMID 18305241 DOI: 10.1523/JNEUROSCI.2973-07.2008  0.68
2008 Tsui I, Fuchs BS, Chou CL, Chang S, Tsang SH. Non-vascular vision loss in pseudoxanthoma elasticum. Documenta Ophthalmologica. Advances in Ophthalmology. 117: 65-7. PMID 18034271 DOI: 10.1007/s10633-007-9100-y  0.36
2008 Tsui I, Casper D, Chou CL, Tsang SH. Electronegative electroretinogram associated with topiramate toxicity and vitelliform maculopathy. Documenta Ophthalmologica. Advances in Ophthalmology. 116: 57-60. PMID 17912565 DOI: 10.1007/s10633-007-9084-7  0.36
2007 Audo I, Tsang SH, Fu AD, Barnes JA, Holder GE, Moore AT. Autofluorescence imaging in a case of benign familial fleck retina. Archives of Ophthalmology (Chicago, Ill. : 1960). 125: 714-5. PMID 17502520 DOI: 10.1001/archopht.125.5.714  0.68
2007 Tsang SH, Woodruff ML, Jun L, Mahajan V, Yamashita CK, Pedersen R, Lin CS, Goff SP, Rosenberg T, Larsen M, Farber DB, Nusinowitz S. Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness. Human Mutation. 28: 243-54. PMID 17044014 DOI: 10.1002/humu.20425  0.68
2003 Farber DB, Tsang SH. Stationary night blindness or progressive retinal degeneration in mice carrying different alleles of PDE gamma. Frontiers in Bioscience : a Journal and Virtual Library. 8: s666-75. PMID 12700134  0.68
2002 Tsang SH, Yamashita CK, Lee WH, Lin CS, Goff SP, Gouras P, Farber DB. The positive role of the carboxyl terminus of the gamma subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo. Vision Research. 42: 439-45. PMID 11853759 DOI: 10.1016/S0042-6989(01)00213-9  0.68
2001 Tsang SH, Yamashita CK, Doi K, Salchow DJ, Bouvier N, Mendelsohn M, Gouras P, Farber DB, Goff SP. In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84. The Biochemical Journal. 353: 467-74. PMID 11171042 DOI: 10.1042/0264-6021:3530467  0.68
1998 Tsang SH, Burns ME, Calvert PD, Gouras P, Baylor DA, Goff SP, Arshavsky VY. Role for the target enzyme in deactivation of photoreceptor G protein in vivo. Science (New York, N.Y.). 282: 117-21. PMID 9756475 DOI: 10.1126/science.282.5386.117  0.68
1996 Tsang SH, Gouras P, Yamashita CK, Kjeldbye H, Fisher J, Farber DB, Goff SP. Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase. Science (New York, N.Y.). 272: 1026-9. PMID 8638127  0.68
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