| Year |
Citation |
Score |
| 2019 |
Siebert DCB, Sommer R, Pogorevc D, Hoffmann M, Wenzel SC, Müller R, Titz A. Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis. Beilstein Journal of Organic Chemistry. 15: 2922-2929. PMID 31839838 DOI: 10.3762/Bjoc.15.286 |
0.652 |
|
| 2019 |
Sommer R, Rox K, Wagner S, Hauck D, Henrikus S, Newsad S, Arnold T, Ryckmans T, Brönstrup M, Imberty A, Varrot A, Hartmann RW, Titz A. Anti-Biofilm Agents against Pseudomonas aeruginosa: a Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. Journal of Medicinal Chemistry. PMID 31553873 DOI: 10.1021/Acs.Jmedchem.9B01120 |
0.791 |
|
| 2019 |
Taouai M, Chakroun K, Sommer R, Michaud G, Giacalone D, Ben Maaouia MA, Vallin-Butruille A, Mathiron D, Abidi R, Darbre T, Cragg PJ, Mullié C, Reymond JL, O'Toole GA, Benazza M. Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms. Journal of Medicinal Chemistry. PMID 31449405 DOI: 10.1021/Acs.Jmedchem.9B00481 |
0.369 |
|
| 2019 |
Lepsik M, Sommer R, Kuhaudomlarp S, Lelimousin M, Paci E, Varrot A, Titz A, Imberty A. Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study. European Journal of Medicinal Chemistry. 177: 212-220. PMID 31146126 DOI: 10.1016/J.Ejmech.2019.05.049 |
0.654 |
|
| 2018 |
Akduman N, Rödelsperger C, Sommer RJ. Culture-based analysis of Pristionchus-associated microbiota from beetles and figs for studying nematode-bacterial interactions. Plos One. 13: e0198018. PMID 29864131 DOI: 10.1371/journal.pone.0198018 |
0.306 |
|
| 2018 |
Sommer R, Makshakova ON, Wohlschlager T, Hutin S, Marsh M, Titz A, Künzler M, Varrot A. Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense. Structure (London, England : 1993). 26: 391-402.e4. PMID 29398527 DOI: 10.1016/J.Str.2018.01.003 |
0.666 |
|
| 2017 |
Sommer R, Wagner S, Rox K, Varrot A, Hauck D, Wamhoff EC, Schreiber J, Ryckmans T, Brunner T, Rademacher C, Hartmann RW, Brönstrup M, Imberty A, Titz A. Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society. PMID 29272578 DOI: 10.1021/Jacs.7B11133 |
0.792 |
|
| 2017 |
Wagner S, Hauck D, Hoffmann M, Sommer R, Joachim I, Müller R, Imberty A, Varrot A, Titz A. Covalent lectin inhibition and application in bacterial biofilm imaging. Angewandte Chemie (International Ed. in English). PMID 28960731 DOI: 10.1002/Anie.201709368 |
0.792 |
|
| 2017 |
Huggins WM, Minrovic BM, Corey BW, Jacobs AC, Melander RJ, Sommer RD, Zurawski DV, Melander C. 1,2,4-Triazolidine-3-thiones as Narrow Spectrum Antibiotics against Multidrug-Resistant Acinetobacter baumannii. Acs Medicinal Chemistry Letters. 8: 27-31. PMID 28105270 DOI: 10.1021/Acsmedchemlett.6B00296 |
0.34 |
|
| 2016 |
Sommer R, Wagner S, Varrot A, Nycholat CM, Khaledi A, Häussler S, Paulson JC, Imberty A, Titz A. The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery. Chemical Science. 7: 4990-5001. PMID 30155149 DOI: 10.1039/C6Sc00696E |
0.766 |
|
| 2016 |
Sommer R, Hauck D, Varrot A, Imberty A, Künzler M, Titz A. -Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2--methyl-L-selenofucopyranoside. Beilstein Journal of Organic Chemistry. 12: 2828-2833. PMID 28144356 DOI: 10.3762/Bjoc.12.282 |
0.637 |
|
| 2016 |
Joachim I, Rikker S, Hauck D, Ponader D, Boden S, Sommer R, Hartmann L, Titz A. Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa. Organic & Biomolecular Chemistry. PMID 27488655 DOI: 10.1039/C6Ob01313A |
0.746 |
|
| 2016 |
Wagner S, Sommer R, Hinsberger S, Lu C, Hartmann RW, Empting M, Titz A. Novel Strategies for the treatment of Pseudomonas aeruginosa infections. Journal of Medicinal Chemistry. PMID 26804741 DOI: 10.1021/Acs.Jmedchem.5B01698 |
0.757 |
|
| 2016 |
Beshr G, Sommer R, Hauck D, Siebert DCB, Hofmann A, Imberty A, Titz A. Development of a competitive binding assay for the Burkholderia cenocepacia lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors Medchemcomm. 7: 519-530. DOI: 10.1039/C5Md00557D |
0.701 |
|
| 2015 |
Sommer R, Hauck D, Varrot A, Wagner S, Audfray A, Prestel A, Möller HM, Imberty A, Titz A. Cinnamide Derivatives of d-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa. Chemistryopen. 4: 756-67. PMID 27308201 DOI: 10.1002/Open.201500162 |
0.806 |
|
| 2015 |
Hofmann A, Sommer R, Hauck D, Stifel J, Göttker-Schnetmann I, Titz A. Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa. Carbohydrate Research. 412: 34-42. PMID 26004349 DOI: 10.1016/J.Carres.2015.04.010 |
0.748 |
|
| 2015 |
Sommer R, Hauck D, Varrot A, Wagner S, Audfray A, Prestel A, Möller HM, Imberty A, Titz A. Cinnamide Derivatives of d-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa Chemistryopen. DOI: 10.1002/open.201500162 |
0.654 |
|
| 2014 |
Sommer R, Exner TE, Titz A. A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB. Plos One. 9: e112822. PMID 25415418 DOI: 10.1371/Journal.Pone.0112822 |
0.761 |
|
| 2013 |
Sommer R, Joachim I, Wagner S, Titz A. New approaches to control infections: anti-biofilm strategies against gram-negative bacteria. Chimia. 67: 286-90. PMID 23967708 DOI: 10.2533/Chimia.2013.286 |
0.772 |
|
| 2012 |
Miller RE, Sommer R, Fan H, Snieckus V, Groth U. Combined directed metalation-suzuki-miyaura cross coupling strategies. Synthesis of isomeric chromenopyridinones and related annulated analogues Heterocycles. 86: 1045-1054. DOI: 10.3987/Com-12-S(N)131 |
0.523 |
|
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