| Year |
Citation |
Score |
| 2024 |
Vithani N, Todd TD, Singh S, Trent T, Blumer KJ, Bowman GR. G Protein Activation Occurs via a Largely Universal Mechanism. The Journal of Physical Chemistry. B. PMID 38580321 DOI: 10.1021/acs.jpcb.3c07028 |
0.335 |
|
| 2023 |
Onken MD, Erdmann-Gilmore P, Zhang Q, Thapa K, King E, Kaltenbronn KM, Noda SE, Makepeace CM, Goldfarb D, Babur Ö, Townsend RR, Blumer KJ. Protein kinase signaling networks driven by oncogenic Gq/11 in uveal melanoma identified by phosphoproteomic and bioinformatic analyses. Molecular & Cellular Proteomics : McP. 100649. PMID 37730182 DOI: 10.1016/j.mcpro.2023.100649 |
0.301 |
|
| 2021 |
Onken MD, Makepeace CM, Kaltenbronn KM, Choi J, Hernandez-Aya L, Weilbaecher KN, Piggott KD, Rao PK, Yuede CM, Dixon AJ, Osei-Owusu P, Cooper JA, Blumer KJ. Targeting primary and metastatic uveal melanoma with a G protein inhibitor. The Journal of Biological Chemistry. 100403. PMID 33577798 DOI: 10.1016/j.jbc.2021.100403 |
0.654 |
|
| 2018 |
Sun X, Singh S, Blumer K, Bowman GR. Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding. Elife. 7. PMID 30289386 DOI: 10.7554/Elife.38465 |
0.38 |
|
| 2018 |
Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ. Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells. Science Signaling. 11. PMID 30181242 DOI: 10.1126/Scisignal.Aao6852 |
0.402 |
|
| 2018 |
Sun X, Singh S, Blumer KJ, Bowman GR. Author response: Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding Elife. DOI: 10.7554/Elife.38465.031 |
0.368 |
|
| 2018 |
Onken MD, Makepeace CM, Wang S, Kaltenbronn KM, Kanai SM, Broekelmann TJ, Cooper JA, Blumer KJ. Abstract 4363: Pharmacologic targeting of Gq reveals new pathways in uveal melanoma Cancer Research. 78: 4363-4363. DOI: 10.1158/1538-7445.Am2018-4363 |
0.375 |
|
| 2018 |
Singh S, Sun X, Blumer KJ, Bowman GR. Direct Observation of GDP Unbinding Reveals Multiple Allosteric Pathways Underlie G-Protein Activation Biophysical Journal. 114: 398a. DOI: 10.1016/J.Bpj.2017.11.2202 |
0.444 |
|
| 2017 |
Kanai SM, Edwards AJ, Rurik JG, Osei-Owusu P, Blumer KJ. Proteolytic degradation of Regulator of G Protein Signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. The Journal of Biological Chemistry. PMID 28974581 DOI: 10.1074/Jbc.M117.797134 |
0.752 |
|
| 2017 |
Scherer SL, Cain MD, Kanai SM, Kaltenbronn KM, Blumer KJ. Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13. The Journal of Biological Chemistry. PMID 28432124 DOI: 10.1074/Jbc.M116.771923 |
0.378 |
|
| 2017 |
Onken MD, Makepeace CM, Wang S, Kaltenbronn KM, Kanai SM, Broekelmann TJ, Cooper JA, Blumer KJ. Abstract 1350: Direct pharmacological targeting of Gq/11 in uveal melanoma Cancer Research. 77: 1350-1350. DOI: 10.1158/1538-7445.Am2017-1350 |
0.331 |
|
| 2015 |
Beeman SC, Osei-Owusu P, Duan C, Engelbach J, Bretthorst GL, Ackerman JJH, Blumer KJ, Garbow JR. Renal DCE-MRI Model Selection Using Bayesian Probability Theory. Tomography (Ann Arbor, Mich.). 1: 61-68. PMID 30042955 DOI: 10.18383/j.tom.2015.00133 |
0.604 |
|
| 2015 |
Osei-Owusu P, Owens EA, Jie L, Reis JS, Forrester SJ, Kawai T, Eguchi S, Singh H, Blumer KJ. Regulation of Renal Hemodynamics and Function by RGS2. Plos One. 10: e0132594. PMID 26193676 DOI: 10.1371/Journal.Pone.0132594 |
0.698 |
|
| 2015 |
Osei-Owusu P, Blumer KJ. Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function. Progress in Molecular Biology and Translational Science. 133: 77-92. PMID 26123303 DOI: 10.1016/Bs.Pmbts.2015.02.001 |
0.753 |
|
| 2015 |
Rensing DT, Uppal S, Blumer KJ, Moeller KD. Toward the Selective Inhibition of G Proteins: Total Synthesis of a Simplified YM-254890 Analog. Organic Letters. 17: 2270-3. PMID 25875152 DOI: 10.1021/Acs.Orglett.5B00944 |
0.303 |
|
| 2015 |
Osei-Owusu P, Blumer KJ. Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function Progress in Molecular Biology and Translational Science. 133: 77-92. DOI: 10.1016/bs.pmbts.2015.02.001 |
0.726 |
|
| 2014 |
Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Nakamura R, Lavine KJ, Blumer KJ, Choi K, Apte RS, et al. Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: 13379-84. PMID 25139991 DOI: 10.1073/Pnas.1324235111 |
0.691 |
|
| 2014 |
Osei-Owusu P, Knutsen RH, Kozel BA, Dietrich HH, Blumer KJ, Mecham RP. Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency. American Journal of Physiology. Heart and Circulatory Physiology. 306: H654-66. PMID 24414067 DOI: 10.1152/Ajpheart.00601.2013 |
0.694 |
|
| 2014 |
Jia L, Chisari M, Maktabi MH, Sobieski C, Zhou H, Konopko AM, Martin BR, Mennerick SJ, Blumer KJ. A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation. The Journal of Biological Chemistry. 289: 6249-57. PMID 24385443 DOI: 10.1074/Jbc.M113.531475 |
0.463 |
|
| 2013 |
Cain MD, Vo BQ, Kolesnikov AV, Kefalov VJ, Culican SM, Kerschensteiner D, Blumer KJ. An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina. Plos One. 8: e82276. PMID 24349243 DOI: 10.1371/Journal.Pone.0082276 |
0.407 |
|
| 2013 |
Li A, Knutsen RH, Zhang H, Osei-Owusu P, Moreno-Dominguez A, Harter TM, Uchida K, Remedi MS, Dietrich HH, Bernal-Mizrachi C, Blumer KJ, Mecham RP, Koster JC, Nichols CG. Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle. Journal of the American Heart Association. 2: e000365. PMID 23974906 DOI: 10.1161/Jaha.113.000365 |
0.692 |
|
| 2012 |
Zhou H, Chisari M, Raehal KM, Kaltenbronn KM, Bohn LM, Mennerick SJ, Blumer KJ. GIRK channel modulation by assembly with allosterically regulated RGS proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 19977-82. PMID 23169654 DOI: 10.1073/Pnas.1214337109 |
0.417 |
|
| 2012 |
Osei-Owusu P, Sabharwal R, Kaltenbronn KM, Rhee MH, Chapleau MW, Dietrich HH, Blumer KJ. Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signaling. The Journal of Biological Chemistry. 287: 12541-9. PMID 22354966 DOI: 10.1074/Jbc.M111.332130 |
0.73 |
|
| 2011 |
Jia L, Linder ME, Blumer KJ. Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. The Journal of Biological Chemistry. 286: 13695-703. PMID 21343290 DOI: 10.1074/Jbc.M110.193763 |
0.421 |
|
| 2011 |
Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RP. RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling. Journal of Molecular and Cellular Cardiology. 50: 1000-7. PMID 21291891 DOI: 10.1016/J.Yjmcc.2011.01.015 |
0.382 |
|
| 2009 |
Inoue-Mochita M, Inoue T, Epstein DL, Blumer KJ, Rao PV. RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival. Molecular Vision. 15: 495-504. PMID 19262744 |
0.366 |
|
| 2009 |
Jayaraman M, Zhou H, Jia L, Cain MD, Blumer KJ. R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling. Trends in Pharmacological Sciences. 30: 17-24. PMID 19042037 DOI: 10.1016/J.Tips.2008.10.002 |
0.465 |
|
| 2008 |
Grabowska D, Jayaraman M, Kaltenbronn KM, Sandiford SL, Wang Q, Jenkins S, Slepak VZ, Smith Y, Blumer KJ. Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain. Neuroscience. 151: 969-82. PMID 18248908 DOI: 10.1016/J.Neuroscience.2007.11.045 |
0.402 |
|
| 2008 |
Gu S, Anton A, Salim S, Blumer KJ, Dessauer CW, Heximer SP. Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins. Molecular Pharmacology. 73: 1-11. PMID 17901199 DOI: 10.1124/Mol.107.036285 |
0.471 |
|
| 2007 |
Blumer KJ, Thorner J. An adrenaline (and gold?) rush for the GPCR community. Acs Chemical Biology. 2: 783-6. PMID 18154265 DOI: 10.1021/Cb7002412 |
0.361 |
|
| 2007 |
Osei-Owusu P, Sun X, Drenan RM, Steinberg TH, Blumer KJ. Regulation of RGS2 and second messenger signaling in vascular smooth muscle cells by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 282: 31656-65. PMID 17681944 DOI: 10.1074/Jbc.M706360200 |
0.718 |
|
| 2007 |
Tank J, Obst M, Diedrich A, Brychta RJ, Blumer KJ, Heusser K, Jordan J, Luft FC, Gross V. Sympathetic nerve traffic and circulating norepinephrine levels in RGS2-deficient mice. Autonomic Neuroscience : Basic & Clinical. 136: 52-7. PMID 17507294 DOI: 10.1016/J.Autneu.2007.04.001 |
0.336 |
|
| 2007 |
Heximer SP, Blumer KJ. RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe2. PMID 17244887 DOI: 10.1126/Stke.3702007Pe2 |
0.415 |
|
| 2006 |
Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/Jbc.M604428200 |
0.395 |
|
| 2006 |
Obst M, Tank J, Plehm R, Blumer KJ, Diedrich A, Jordan J, Luft FC, Gross V. NO-dependent blood pressure regulation in RGS2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R1012-9. PMID 16269576 DOI: 10.1152/Ajpregu.00288.2005 |
0.464 |
|
| 2005 |
Overton MC, Chinault SL, Blumer KJ. Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae. Eukaryotic Cell. 4: 1963-70. PMID 16339714 DOI: 10.1128/Ec.4.12.1963-1970.2005 |
0.461 |
|
| 2005 |
Chang FS, Han GS, Carman GM, Blumer KJ. A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. The Journal of Cell Biology. 171: 133-42. PMID 16216926 DOI: 10.1083/Jcb.200501086 |
0.356 |
|
| 2005 |
Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/Jcb.200502007 |
0.377 |
|
| 2005 |
Gross V, Tank J, Obst M, Plehm R, Blumer KJ, Diedrich A, Jordan J, Luft FC. Autonomic nervous system and blood pressure regulation in RGS2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R1134-42. PMID 15661972 DOI: 10.1152/Ajpregu.00246.2004 |
0.493 |
|
| 2005 |
Sun X, Kaltenbronn KM, Steinberg TH, Blumer KJ. RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling. Molecular Pharmacology. 67: 631-9. PMID 15563583 DOI: 10.1124/Mol.104.007724 |
0.431 |
|
| 2004 |
Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ. G-protein signaling participates in the development of diabetic cardiomyopathy. Diabetes. 53: 3082-90. PMID 15561937 DOI: 10.2337/Diabetes.53.12.3082 |
0.678 |
|
| 2004 |
Larminie C, Murdock P, Walhin JP, Duckworth M, Blumer KJ, Scheideler MA, Garnier M. Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system. Brain Research. Molecular Brain Research. 122: 24-34. PMID 14992813 DOI: 10.1016/J.Molbrainres.2003.11.014 |
0.401 |
|
| 2004 |
Wild AC, Yu JW, Lemmon MA, Blumer KJ. The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. The Journal of Biological Chemistry. 279: 17101-10. PMID 14766750 DOI: 10.1074/Jbc.M314035200 |
0.348 |
|
| 2004 |
Chinault SL, Overton MC, Blumer KJ. Subunits of a yeast oligomeric G protein-coupled receptor are activated independently by agonist but function in concert to activate G protein heterotrimers. The Journal of Biological Chemistry. 279: 16091-100. PMID 14764600 DOI: 10.1074/Jbc.M311099200 |
0.459 |
|
| 2004 |
Tang M, Wang G, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME. Erratum: Corrigendum: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure Nature Medicine. 10: 105-105. DOI: 10.1038/Nm0104-105B |
0.433 |
|
| 2003 |
Blumer KJ, Cooper JA. Go ahead, break my symmetry! Nature Cell Biology. 5: 1048-9. PMID 14647302 DOI: 10.1038/Ncb1203-1048 |
0.325 |
|
| 2003 |
Tang KM, Wang GR, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME, Tang M, Wang G. Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure. Nature Medicine. 9: 1506-12. PMID 14608379 DOI: 10.1038/Nm958 |
0.488 |
|
| 2003 |
Faury G, Pezet M, Knutsen RH, Boyle WA, Heximer SP, McLean SE, Minkes RK, Blumer KJ, Kovacs A, Kelly DP, Li DY, Starcher B, Mecham RP. Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency. The Journal of Clinical Investigation. 112: 1419-28. PMID 14597767 DOI: 10.1172/Jci19028 |
0.339 |
|
| 2003 |
Overton MC, Chinault SL, Blumer KJ. Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 278: 49369-77. PMID 14506226 DOI: 10.1074/Jbc.M308654200 |
0.369 |
|
| 2003 |
Floyd DH, Geva A, Bruinsma SP, Overton MC, Blumer KJ, Baranski TJ. C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast. The Journal of Biological Chemistry. 278: 35354-61. PMID 12835318 DOI: 10.1074/Jbc.M305607200 |
0.33 |
|
| 2003 |
Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ. Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. The Journal of Clinical Investigation. 111: 1259. PMID 12697745 |
0.615 |
|
| 2003 |
Chinault SL, Blumer KJ. The C-terminal tail preceding the CAAX box of a yeast G protein gamma subunit is dispensable for receptor-mediated G protein activation in vivo. The Journal of Biological Chemistry. 278: 20638-44. PMID 12665529 DOI: 10.1074/Jbc.M212701200 |
0.427 |
|
| 2003 |
Chang FS, Stefan CJ, Blumer KJ. A WASp homolog powers actin polymerization-dependent motility of endosomes in vivo. Current Biology : Cb. 13: 455-63. PMID 12646127 DOI: 10.1016/S0960-9822(03)00131-3 |
0.361 |
|
| 2003 |
Garnier M, Zaratin PF, Ficalora G, Valente M, Fontanella L, Rhee MH, Blumer KJ, Scheideler MA. Up-regulation of regulator of G protein signaling 4 expression in a model of neuropathic pain and insensitivity to morphine. The Journal of Pharmacology and Experimental Therapeutics. 304: 1299-306. PMID 12604710 DOI: 10.1124/Jpet.102.043471 |
0.341 |
|
| 2003 |
Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ. Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. The Journal of Clinical Investigation. 111: 445-52. PMID 12588882 DOI: 10.1172/Jci15598 |
0.728 |
|
| 2002 |
Overton MC, Blumer KJ. Use of fluorescence resonance energy transfer to analyze oligomerization of G-protein-coupled receptors expressed in yeast. Methods (San Diego, Calif.). 27: 324-32. PMID 12217648 DOI: 10.1016/S1046-2023(02)00090-7 |
0.39 |
|
| 2002 |
Overton MC, Blumer KJ. The extracellular N-terminal domain and transmembrane domains 1 and 2 mediate oligomerization of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 277: 41463-72. PMID 12194975 DOI: 10.1074/Jbc.M205368200 |
0.311 |
|
| 2001 |
Heximer SP, Lim H, Bernard JL, Blumer KJ. Mechanisms governing subcellular localization and function of human RGS2. The Journal of Biological Chemistry. 276: 14195-203. PMID 11278586 DOI: 10.1074/Jbc.M009942200 |
0.396 |
|
| 2001 |
Rogers JH, Tsirka A, Kovacs A, Blumer KJ, Dorn GW, Muslin AJ. RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice. Journal of Molecular and Cellular Cardiology. 33: 209-18. PMID 11162127 DOI: 10.1006/Jmcc.2000.1307 |
0.64 |
|
| 2000 |
Wu C, Zeng Q, Blumer KJ, Muslin AJ. RGS proteins inhibit Xwnt-8 signaling in Xenopus embryonic development. Development (Cambridge, England). 127: 2773-84. PMID 10851124 |
0.365 |
|
| 2000 |
Overton MC, Blumer KJ. G-protein-coupled receptors function as oligomers in vivo. Current Biology : Cb. 10: 341-4. PMID 10744981 DOI: 10.1016/S0960-9822(00)00386-9 |
0.448 |
|
| 2000 |
Manahan CL, Patnana M, Blumer KJ, Linder ME. Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 11: 957-68. PMID 10712512 DOI: 10.1091/Mbc.11.3.957 |
0.45 |
|
| 1999 |
Heximer SP, Srinivasa SP, Bernstein LS, Bernard JL, Linder ME, Hepler JR, Blumer KJ. G protein selectivity is a determinant of RGS2 function. The Journal of Biological Chemistry. 274: 34253-9. PMID 10567399 DOI: 10.1074/Jbc.274.48.34253 |
0.671 |
|
| 1999 |
Takesono A, Zahner J, Blumer KJ, Nagao T, Kurose H. Negative regulation of alpha2-adrenergic receptor-mediated Gi signalling by a novel pathway. The Biochemical Journal. 343: 77-85. PMID 10493914 DOI: 10.1042/0264-6021:3430077 |
0.435 |
|
| 1999 |
Rogers JH, Tamirisa P, Kovacs A, Weinheimer C, Courtois M, Blumer KJ, Kelly DP, Muslin AJ. RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. The Journal of Clinical Investigation. 104: 567-76. PMID 10487771 DOI: 10.1172/Jci6713 |
0.648 |
|
| 1999 |
Tamirisa P, Blumer KJ, Muslin AJ. RGS4 inhibits G-protein signaling in cardiomyocytes. Circulation. 99: 441-7. PMID 9918533 DOI: 10.1161/01.Cir.99.3.441 |
0.673 |
|
| 1999 |
Stefan CJ, Blumer KJ. A syntaxin homolog encoded by VAM3 mediates down-regulation of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 274: 1835-41. PMID 9880567 DOI: 10.1074/Jbc.274.3.1835 |
0.414 |
|
| 1998 |
Eby JJ, Holly SP, van Drogen F, Grishin AV, Peter M, Drubin DG, Blumer KJ. Actin cytoskeleton organization regulated by the PAK family of protein kinases. Current Biology : Cb. 8: 967-70. PMID 9742399 DOI: 10.1016/S0960-9822(98)00398-4 |
0.356 |
|
| 1998 |
Druey KM, Sullivan BM, Brown D, Fischer ER, Watson N, Blumer KJ, Gerfen CR, Scheschonka A, Kehrl JH. Expression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membrane. The Journal of Biological Chemistry. 273: 18405-10. PMID 9660808 DOI: 10.1074/Jbc.273.29.18405 |
0.455 |
|
| 1998 |
Grishin AV, Rothenberg M, Downs MA, Blumer KJ. Mot3, a Zn finger transcription factor that modulates gene expression and attenuates mating pheromone signaling in Saccharomyces cerevisiae. Genetics. 149: 879-92. PMID 9611199 |
0.324 |
|
| 1998 |
Srinivasa SP, Bernstein LS, Blumer KJ, Linder ME. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 95: 5584-9. PMID 9576926 DOI: 10.1073/Pnas.95.10.5584 |
0.341 |
|
| 1998 |
Stefan CJ, Overton MC, Blumer KJ. Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors. Molecular Biology of the Cell. 9: 885-99. PMID 9529386 DOI: 10.1091/Mbc.9.4.885 |
0.428 |
|
| 1998 |
Zhang S, Watson N, Zahner J, Rottman JN, Blumer KJ, Muslin AJ. RGS3 and RGS4 are GTPase activating proteins in the heart. Journal of Molecular and Cellular Cardiology. 30: 269-76. PMID 9515003 DOI: 10.1006/Jmcc.1997.0591 |
0.678 |
|
| 1998 |
Srinivasa SP, Watson N, Overton MC, Blumer KJ. Mechanism of RGS4, a GTPase-activating protein for G protein alpha subunits. The Journal of Biological Chemistry. 273: 1529-33. PMID 9430692 DOI: 10.1074/Jbc.273.3.1529 |
0.414 |
|
| 1997 |
Heximer SP, Watson N, Linder ME, Blumer KJ, Hepler JR. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proceedings of the National Academy of Sciences of the United States of America. 94: 14389-93. PMID 9405622 DOI: 10.1073/Pnas.94.26.14389 |
0.665 |
|
| 1996 |
Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature. 383: 172-5. PMID 8774882 DOI: 10.1038/383172A0 |
0.441 |
|
| 1996 |
Druey KM, Blumer KJ, Kang VH, Kehrl JH. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature. 379: 742-6. PMID 8602223 DOI: 10.1038/379742A0 |
0.47 |
|
| 1995 |
Richard S, Yu D, Blumer KJ, Hausladen D, Olszowy MW, Connelly PA, Shaw AS. Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1. Molecular and Cellular Biology. 15: 186-97. PMID 7799925 DOI: 10.1128/Mcb.15.1.186 |
0.304 |
|
| 1994 |
Blumer KJ, Johnson GL, Lange-Carter CA. Mammalian mitogen-activated protein kinase kinase kinase (MEKK) can function in a yeast mitogen-activated protein kinase pathway downstream of protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 91: 4925-9. PMID 8197159 DOI: 10.1073/Pnas.91.11.4925 |
0.347 |
|
| 1994 |
Stefan CJ, Blumer KJ. The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization. Molecular and Cellular Biology. 14: 3339-49. PMID 8164685 DOI: 10.1128/Mcb.14.5.3339 |
0.353 |
|
| 1994 |
Blumer KJ, Johnson GL. Diversity in function and regulation of MAP kinase pathways. Trends in Biochemical Sciences. 19: 236-40. PMID 8073500 DOI: 10.1016/0968-0004(94)90147-3 |
0.352 |
|
| 1994 |
Grishin AV, Weiner JL, Blumer KJ. Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein gamma subunit. Molecular and Cellular Biology. 14: 4571-8. PMID 8007961 DOI: 10.1128/Mcb.14.7.4571 |
0.422 |
|
| 1993 |
Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science (New York, N.Y.). 260: 315-9. PMID 8385802 DOI: 10.1126/Science.8385802 |
0.331 |
|
| 1993 |
Weiner JL, Guttierez-Steil C, Blumer KJ. Disruption of receptor-G protein coupling in yeast promotes the function of an SST2-dependent adaptation pathway. The Journal of Biological Chemistry. 268: 8070-7. PMID 8385135 |
0.357 |
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