Paul Kotzbauer - Publications

Affiliations: 
Washington University School of Medicine, St. Louis, MO, United States 

0/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2022 Myers PS, O'Donnell JL, Jackson JJ, Lessov-Schlaggar CN, Miller RL, Foster ER, Cruchaga C, Benitez BA, Kotzbauer PT, Perlmutter JS, Campbell MC. Proteinopathy and Longitudinal Cognitive Decline in Parkinson Disease. Neurology. PMID 35418463 DOI: 10.1212/WNL.0000000000200344  0.01
2022 Zhu J, Pittman S, Dhavale D, French R, Patterson JN, Kaleelurrrahuman MS, Sun Y, Vaquer-Alicea J, Maggiore G, Clemen CS, Buscher WJ, Bieschke J, Kotzbauer P, Ayala Y, Diamond MI, et al. VCP suppresses proteopathic seeding in neurons. Molecular Neurodegeneration. 17: 30. PMID 35414105 DOI: 10.1186/s13024-022-00532-0  0.01
2022 Miller RL, Dhavale DD, O'Shea JY, Andruska KM, Liu J, Franklin EE, Buddhala C, Loftin SK, Cirrito JR, Perrin RJ, Cairns NJ, Campbell MC, Perlmutter JS, Kotzbauer PT. Quantifying regional α -synuclein, amyloid β, and tau accumulation in lewy body dementia. Annals of Clinical and Translational Neurology. PMID 35060360 DOI: 10.1002/acn3.51482  0.01
2020 Martin WRW, Miles M, Zhong Q, Hartlein J, Racette BA, Norris SA, Ushe M, Maiti B, Criswell S, Davis AA, Kotzbauer PT, Cairns NJ, Perrin RJ, Perlmutter JS. Is Levodopa Response a Valid Indicator of Parkinson's Disease? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33253432 DOI: 10.1002/mds.28406  0.01
2020 Ibanez L, Bahena JA, Yang C, Dube U, Farias FHG, Budde JP, Bergmann K, Brenner-Webster C, Morris JC, Perrin RJ, Cairns NJ, O'Donnell J, Álvarez I, Diez-Fairen M, Aguilar M, ... ... Kotzbauer P, et al. Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease. Acta Neuropathologica Communications. 8: 196. PMID 33213513 DOI: 10.1186/s40478-020-01072-8  0.01
2020 Barthélemy NR, Liu H, Lu W, Kotzbauer PT, Bateman RJ, Lucey BP. Sleep deprivation affects tau phosphorylation in human cerebrospinal fluid. Annals of Neurology. PMID 32057125 DOI: 10.1002/ana.25702  0.01
2020 Davis AA, Inman CE, Wargel ZM, Dube U, Freeberg BM, Galluppi A, Haines JN, Dhavale DD, Miller R, Choudhury FA, Sullivan PM, Cruchaga C, Perlmutter JS, Ulrich JD, Benitez BA, ... Kotzbauer PT, et al. genotype regulates pathology and disease progression in synucleinopathy. Science Translational Medicine. 12. PMID 32024799 DOI: 10.1126/Scitranslmed.Aay3069  0.01
2019 Campbell MC, Jackson JJ, Koller JM, Snyder AZ, Kotzbauer PT, Perlmutter JS. Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease. Neurology. PMID 31852813 DOI: 10.1212/Wnl.0000000000008677  0.01
2019 French RL, Grese ZR, Aligireddy H, Dhavale DD, Reeb AN, Kedia N, Kotzbauer PT, Bieschke J, Ayala YM. Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation. The Journal of Biological Chemistry. PMID 30824544 DOI: 10.1074/Jbc.Ra118.005889  0.01
2018 Yamasaki TR, Holmes BB, Furman JL, Dhavale DD, Su BW, Song ES, Cairns NJ, Kotzbauer PT, Diamond MI. Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics. The Journal of Biological Chemistry. PMID 30478174 DOI: 10.1074/Jbc.Ra118.004471  0.01
2018 Hsieh CJ, Xu K, Lee I, Graham TJA, Tu Z, Dhavale D, Kotzbauer P, Mach RH. Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro. Acs Omega. 3: 4486-4493. PMID 30221226 DOI: 10.1021/acsomega.7b01897  0.01
2018 Hsieh CJ, Ferrie JJ, Xu K, Lee I, Graham TJA, Tu Z, Yu J, Dhavale D, Kotzbauer P, Petersson EJ, Mach RH. Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules. Acs Chemical Neuroscience. PMID 29750499 DOI: 10.1021/Acschemneuro.8B00177  0.01
2018 Yue X, Dhavale DD, Li J, Luo Z, Liu J, Yang H, Mach RH, Kotzbauer PT, Tu Z. Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation. Bioorganic & Medicinal Chemistry Letters. PMID 29482941 DOI: 10.1016/J.Bmcl.2018.02.031  0.01
2018 Barclay AM, Dhavale DD, Courtney JM, Kotzbauer PT, Rienstra CM. Resonance assignments of an α-synuclein fibril prepared in Tris buffer at moderate ionic strength. Biomolecular Nmr Assignments. PMID 29476328 DOI: 10.1007/S12104-018-9808-5  0.01
2017 Dhavale DD, Tsai C, Bagchi DP, Engel LA, Sarezky J, Kotzbauer PT. A Sensitive Assay Reveals Structural Requirements for Alpha-Synuclein Fibril Growth. The Journal of Biological Chemistry. PMID 28373279 DOI: 10.1074/jbc.M116.767053  0.01
2016 Sundaram GS, Dhavale DD, Prior JL, Yan P, Cirrito J, Rath NP, Laforest R, Cairns NJ, Lee JM, Kotzbauer PT, Sharma V. Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease. Scientific Reports. 6: 35636. PMID 27805057 DOI: 10.1038/Srep35636  0.01
2015 Chuang DY, Simonyi A, Kotzbauer PT, Gu Z, Sun GY. Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway. Journal of Neuroinflammation. 12: 199. PMID 26520095 DOI: 10.1186/S12974-015-0419-0  0.01
2015 Buddhala C, Loftin SK, Kuley BM, Cairns NJ, Campbell MC, Perlmutter JS, Kotzbauer PT. Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease. Annals of Clinical and Translational Neurology. 2: 949-59. PMID 26478895 DOI: 10.1002/Acn3.246  0.01
2015 Chu W, Zhou D, Gaba V, Liu J, Li S, Peng X, Xu J, Dhavale D, Bagchi DP, d'Avignon A, Shakerdge NB, Bacskai BJ, Tu Z, Kotzbauer PT, Mach RH. Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils. Journal of Medicinal Chemistry. 58: 6002-17. PMID 26177091 DOI: 10.1021/Acs.Jmedchem.5B00571  0.01
2015 Sundaram GS, Dhavale D, Prior JL, Sivapackiam J, Laforest R, Kotzbauer P, Sharma V. Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer's disease. Ejnmmi Research. 5: 112. PMID 26061601 DOI: 10.1186/s13550-015-0112-4  0.01
2015 Campbell MC, Koller JM, Snyder AZ, Buddhala C, Kotzbauer PT, Perlmutter JS. CSF proteins and resting-state functional connectivity in Parkinson disease. Neurology. 84: 2413-21. PMID 25979701 DOI: 10.1212/Wnl.0000000000001681  0.01
2015 Buddhala C, Campbell MC, Perlmutter JS, Kotzbauer PT. Correlation between decreased CSF α-synuclein and Aβ₁₋₄₂ in Parkinson disease. Neurobiology of Aging. 36: 476-84. PMID 25212463 DOI: 10.1016/J.Neurobiolaging.2014.07.043  0.01
2014 Zhang X, Jin H, Padakanti PK, Li J, Yang H, Fan J, Mach RH, Kotzbauer P, Tu Z. Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein. Applied Sciences (Basel, Switzerland). 4: 66-78. PMID 25642331 DOI: 10.3390/App4010066  0.01
2014 Armstrong RA, Kotzbauer PT, Perlmutter JS, Campbell MC, Hurth KM, Schmidt RE, Cairns NJ. A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 171-81. PMID 23996276 DOI: 10.1007/S00702-013-1084-Z  0.01
2013 Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proceedings of the National Academy of Sciences of the United States of America. 110: E3138-47. PMID 23898162 DOI: 10.1073/Pnas.1301440110  0.01
2013 Bagchi DP, Yu L, Perlmutter JS, Xu J, Mach RH, Tu Z, Kotzbauer PT. Binding of the Radioligand SIL23 to α-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging Agent Plos One. 8. PMID 23405108 DOI: 10.1371/Journal.Pone.0055031  0.01
2012 Racette BA, Criswell SR, Lundin JI, Hobson A, Seixas N, Kotzbauer PT, Evanoff BA, Perlmutter JS, Zhang J, Sheppard L, Checkoway H. Increased risk of parkinsonism associated with welding exposure. Neurotoxicology. 33: 1356-61. PMID 22975422 DOI: 10.1016/J.Neuro.2012.08.011  0.01
2012 Kotzbauer PT, Cairns NJ, Campbell MC, Willis AW, Racette BA, Tabbal SD, Perlmutter JS. Pathologic accumulation of α-synuclein and Aβ in Parkinson disease patients with dementia. Archives of Neurology. 69: 1326-31. PMID 22825369 DOI: 10.1001/Archneurol.2012.1608  0.01
2012 Yu L, Cui J, Padakanti PK, Engel L, Bagchi DP, Kotzbauer PT, Tu Z. Synthesis and in vitro evaluation of α-synuclein ligands. Bioorganic & Medicinal Chemistry. 20: 4625-34. PMID 22789706 DOI: 10.1016/J.Bmc.2012.06.023  0.01
2010 Engel LA, Jing Z, O'Brien DE, Sun M, Kotzbauer PT. Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism. Plos One. 5: e12897. PMID 20886109 DOI: 10.1371/journal.pone.0012897  0.01
2010 Li M, Husic N, Lin Y, Christensen H, Malik I, McIver S, LaPash Daniels CM, Harris DA, Kotzbauer PT, Goldberg MP, Snider BJ. Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells. Journal of Neuroscience Methods. 189: 56-64. PMID 20347873 DOI: 10.1016/J.Jneumeth.2010.03.019  0.01
2009 Mancuso DJ, Kotzbauer P, Wozniak DF, Sims HF, Jenkins CM, Guan S, Han X, Yang K, Sun G, Malik I, Conyers S, Green KG, Schmidt RE, Gross RW. Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction. The Journal of Biological Chemistry. 284: 35632-44. PMID 19840936 DOI: 10.1074/Jbc.M109.055194  0.01
2008 Gao HM, Kotzbauer PT, Uryu K, Leight S, Trojanowski JQ, Lee VM. Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7687-98. PMID 18650345 DOI: 10.1523/Jneurosci.0143-07.2008  0.01
2008 Malik I, Turk J, Mancuso DJ, Montier L, Wohltmann M, Wozniak DF, Schmidt RE, Gross RW, Kotzbauer PT. Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations. The American Journal of Pathology. 172: 406-16. PMID 18202189 DOI: 10.2353/Ajpath.2008.070823  0.01
2006 Kotzbauer PT, Holtzman DM. Expectations and challenges in the therapeutic use of neurotrophic factors. Annals of Neurology. 59: 444-7. PMID 16489617 DOI: 10.1002/Ana.20794  0.01
2006 Liang TW, Truax AC, Trojanowski JQ, Lee VM, Stern MB, Kotzbauer PT. Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 718-22. PMID 16450344 DOI: 10.1002/Mds.20797  0.01
2005 Kotzbauer PT, Truax AC, Trojanowski JQ, Lee VM. Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 689-98. PMID 15659606 DOI: 10.1523/Jneurosci.4265-04.2005  0.01
2004 Kotzbauer PT, Giasson BI, Kravitz AV, Golbe LI, Mark MH, Trojanowski JQ, Lee VM. Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. Experimental Neurology. 187: 279-88. PMID 15144854 DOI: 10.1016/J.Expneurol.2004.01.007  0.01
2003 Giasson BI, Forman MS, Higuchi M, Golbe LI, Graves CL, Kotzbauer PT, Trojanowski JQ, Lee VM. Initiation and synergistic fibrillization of tau and alpha-synuclein. Science (New York, N.Y.). 300: 636-40. PMID 12714745 DOI: 10.1126/Science.1082324  0.01
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