Year |
Citation |
Score |
2016 |
Buckton LK, Wang Y, McConnell JR, McAlpine SR. Evaluating dual Hsp90 and Hsp70 inhibition as a cancer therapy Topics in Medicinal Chemistry. 19: 55-80. DOI: 10.1007/7355_2015_96 |
0.788 |
|
2015 |
McConnell JR, Buckton LK, McAlpine SR. Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach. Bioorganic & Medicinal Chemistry Letters. 25: 3409-14. PMID 26164188 DOI: 10.1016/J.Bmcl.2015.06.052 |
0.777 |
|
2015 |
Koay YC, McConnell JR, Wang Y, McAlpine SR. Blocking the heat shock response and depleting HSF-1 levels through heat shock protein 90 (hsp90) inhibition: A significant advance on current hsp90 chemotherapies Rsc Advances. 5: 59003-59013. DOI: 10.1039/C5Ra07056B |
0.82 |
|
2014 |
Koay YC, McConnell JR, Wang Y, Kim SJ, Buckton LK, Mansour F, McAlpine SR. Chemically accessible hsp90 inhibitor that does not induce a heat shock response. Acs Medicinal Chemistry Letters. 5: 771-6. PMID 25050163 DOI: 10.1021/Ml500114P |
0.746 |
|
2014 |
McConnell JR, Alexander LA, McAlpine SR. A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock response. Bioorganic & Medicinal Chemistry Letters. 24: 661-6. PMID 24360559 DOI: 10.1016/J.Bmcl.2013.11.059 |
0.812 |
|
2014 |
Pietkiewicz AL, Wahyudi H, McConnell JR, McAlpine SR. Synthesis of macrocycles that inhibit protein synthesis: Stereochemistry and structural based studies on sanguinamide B derivatives Tetrahedron Letters. 55: 6979-6982. DOI: 10.1016/J.Tetlet.2014.10.089 |
0.656 |
|
2013 |
McConnell JR, Rananaware DP, Ramsey DM, Buys KN, Cole ML, McAlpine SR. A potential rhodium cancer therapy: studies of a cytotoxic organorhodium(I) complex that binds DNA. Bioorganic & Medicinal Chemistry Letters. 23: 2527-31. PMID 23541673 DOI: 10.1016/J.Bmcl.2013.03.016 |
0.568 |
|
2013 |
McConnell JR, McAlpine SR. Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets. Bioorganic & Medicinal Chemistry Letters. 23: 1923-8. PMID 23453837 DOI: 10.1016/J.Bmcl.2013.02.014 |
0.72 |
|
2012 |
Ramsey DM, McConnell JR, Alexander LD, Tanaka KW, Vera CM, McAlpine SR. An Hsp90 modulator that exhibits a unique mechanistic profile. Bioorganic & Medicinal Chemistry Letters. 22: 3287-90. PMID 22480433 DOI: 10.1016/J.Bmcl.2012.03.012 |
0.809 |
|
2011 |
Kunicki JB, Petersen MN, Alexander LD, Ardi VC, McConnell JR, McAlpine SR. Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90. Bioorganic & Medicinal Chemistry Letters. 21: 4716-9. PMID 21764310 DOI: 10.1016/J.Bmcl.2011.06.083 |
0.741 |
|
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