| Year |
Citation |
Score |
| 2013 |
Sunassee SN, Veale CG, Shunmoogam-Gounden N, Osoniyi O, Hendricks DT, Caira MR, de la Mare JA, Edkins AL, Pinto AV, da Silva Júnior EN, Davies-Coleman MT. Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells. European Journal of Medicinal Chemistry. 62: 98-110. PMID 23353747 DOI: 10.1016/J.Ejmech.2012.12.048 |
0.357 |
|
| 2012 |
Carneiro PF, do Nascimento SB, Pinto AV, Pinto Mdo C, Lechuga GC, Santos DO, dos Santos Júnior HM, Resende JA, Bourguignon SC, Ferreira VF. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms. Bioorganic & Medicinal Chemistry. 20: 4995-5000. PMID 22795899 DOI: 10.1016/J.Bmc.2012.06.027 |
0.515 |
|
| 2012 |
Fernandes MC, Silva END, Pinto AV, Castro SLD, Menna-Barreto RFS. A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi Parasitology. 139: 26-36. PMID 21939585 DOI: 10.1017/S0031182011001612 |
0.323 |
|
| 2011 |
Carneiro PF, Pinto Mdo C, Coelho TS, Cavalcanti BC, Pessoa C, de Simone CA, Nunes IK, de Oliveira NM, de Almeida RG, Pinto AV, de Moura KC, da Silva PA, da Silva Júnior EN. Quinonoid and phenazine compounds: synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 46: 4521-9. PMID 21820768 DOI: 10.1016/J.Ejmech.2011.07.026 |
0.347 |
|
| 2011 |
Ferreira SB, Salomão K, De Carvalho Da Silva F, Pinto AV, Kaiser CR, Pinto AC, Ferreira VF, De Castro SL. Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues European Journal of Medicinal Chemistry. 46: 3071-3077. PMID 21450374 DOI: 10.1016/J.Ejmech.2011.03.012 |
0.547 |
|
| 2011 |
da Silva EN, Cavalcanti BC, Guimarães TT, Pinto Mdo C, Cabral IO, Pessoa C, Costa-Lotufo LV, de Moraes MO, de Andrade CK, Dos Santos MR, de Simone CA, Goulart MO, Pinto AV. Synthesis and evaluation of quinonoid compounds against tumor cell lines. European Journal of Medicinal Chemistry. 46: 399-410. PMID 21115213 DOI: 10.1016/J.Ejmech.2010.11.006 |
0.381 |
|
| 2011 |
Lourenço AL, Abreu PA, Leal B, da Silva Júnior EN, Pinto AV, Pinto Mdo C, Souza AM, Novais JS, Paiva MB, Cabral LM, Rodrigues CR, Ferreira VF, Castro HC. Identification of nor-β-lapachone derivatives as potential antibacterial compounds against Enterococcus faecalis clinical strain. Current Microbiology. 62: 684-9. PMID 20882284 DOI: 10.1007/S00284-010-9763-6 |
0.539 |
|
| 2011 |
Da Silva MJ, Pinto MDCFR, De Simone CA, Soares JG, Reys JRM, De Souza Filho JD, Harrison WTA, Carvalho CEM, Goulart MOF, Da Silva Júnior EN, Pinto AV. Synthesis and characterisation of a new polycyclic phenazine from 1,4-naphthoquinone Tetrahedron Letters. 52: 2415-2418. DOI: 10.1016/J.Tetlet.2011.03.006 |
0.374 |
|
| 2010 |
da Silva EN, Guimarães TT, Menna-Barreto RF, Pinto Mdo C, de Simone CA, Pessoa C, Cavalcanti BC, Sabino JR, Andrade CK, Goulart MO, de Castro SL, Pinto AV. The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles. Bioorganic & Medicinal Chemistry. 18: 3224-30. PMID 20378360 DOI: 10.1016/J.Bmc.2010.03.029 |
0.373 |
|
| 2010 |
Da Silva EN, De Deus CF, Cavalcanti BC, Pessoa C, Costa-Lotufo LV, Montenegro RC, De Moraes MO, Pinto MDCFR, De Simone CA, Ferreira VF, Goulart MOF, Andrade CKZ, Pinto AV. 3-Arylamino and 3-alkoxy-nor-β-lapachone derivatives: Synthesis and cytotoxicity against cancer cell lines Journal of Medicinal Chemistry. 53: 504-508. PMID 19947600 DOI: 10.1021/Jm900865M |
0.547 |
|
| 2010 |
Souza AAd, Moura MABFd, Abreu FCd, Goulart MOF, ENdSJ, Pinto AV, Ferreira VF, Moscoso R, Núñez-Vergara LJ, Squella JA. Electrochemical study, on mercury, of a Meta-nitroarylamine derivative of nor-β-lapachone, an antitumor and trypanocidal compound QuíMica Nova. 33: 2075-2079. DOI: 10.1590/S0100-40422010001000013 |
0.516 |
|
| 2009 |
Guimarães TT, Da Silva Júnior EN, Carvalho CE, De Simone CA, Pinto AV. 2-(4-Methyl-phen-yl)-1H-anthraceno[1,2-d]imidazole-6,11-dione: a fluorescent chemosensor. Acta Crystallographica. Section E, Structure Reports Online. 65: o1063. PMID 21583879 DOI: 10.1107/S1600536809013634 |
0.323 |
|
| 2009 |
Pinto AV, Castro SLd. The trypanocidal activity of naphthoquinones: a review. Molecules. 14: 4570-4590. PMID 19924086 DOI: 10.3390/Molecules14114570 |
0.331 |
|
| 2009 |
Ribeiro KAL, Carvalho CMd, Molina MT, Lima EP, López-Montero E, Reys JRM, Oliveira MBFd, Pinto AV, Santana AEG, Goulart MOF. Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni Acta Tropica. 111: 44-50. PMID 19426662 DOI: 10.1016/J.Actatropica.2009.02.008 |
0.365 |
|
| 2009 |
Silva RS, Pinto Mdo C, Goulart MO, de Souza Filho JD, Neves I, Lourenço MC, Pinto AV. A macrolactone from benzo[a]phenazine with potent activity against Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 44: 2334-7. PMID 18662840 DOI: 10.1016/J.Ejmech.2008.06.014 |
0.377 |
|
| 2009 |
Eufrânio N, Aline M, Moura BFd, Pinto AV, Carmo Md, Pinto FR, Araújo AJ, Pessoa C, Costa-Lotufo LV, Montenegro RC, Ferreira VF, Goulart MOF. Cytotoxic, Trypanocidal Activities and Physicochemical Parameters of nor-β-Lapachone-based 1,2,3-Triazoles Journal of the Brazilian Chemical Society. 20: 635-643. DOI: 10.1590/S0103-50532009000400007 |
0.509 |
|
| 2009 |
da Silva Júnior EN, de Simone CA, de Souza ACB, Pinto CN, Guimarães TT, Pinto MdCFR, Pinto AV. Unexpected transformation of quinones to spirolactones and to naturally occurring naphthalenic compounds Tetrahedron Letters. 50: 1550-1553. DOI: 10.1016/J.Tetlet.2009.01.058 |
0.366 |
|
| 2008 |
da Silva EN, De Simone CA, Goulart MO, Andrade CK, Silva RS, Pinto AV. 3-(2,4-Dibromo-anilino)-2,2-dimethyl-2,3-dihydro-naphtho[1,2-b]furan-4,5-dione: a new substituted aryl-amino nor-β-lapachone derivative. Acta Crystallographica. Section E, Structure Reports Online. 64: o2348. PMID 21581322 DOI: 10.1107/S1600536808034545 |
0.36 |
|
| 2008 |
Hernández DM, de Moura MA, Valencia DP, González FJ, González I, de Abreu FC, da Silva Júnior EN, Ferreira VF, Pinto AV, Goulart MO, Frontana C. Inner reorganization during the radical-biradical transition in a nor-beta-lapachone derivative possessing two redox centers. Organic & Biomolecular Chemistry. 6: 3414-20. PMID 18802650 DOI: 10.1039/B806271D |
0.47 |
|
| 2008 |
da Silva Júnior EN, de Souza MC, Pinto AV, Pinto Mdo C, Nogueira CM, Ferreira VF, Azeredo RB. Complete and unambiguous assignments of 1H and 13C chemical shifts of new arylamino derivatives of ortho-naphthofuranquinones. Magnetic Resonance in Chemistry : Mrc. 46: 1158-62. PMID 18524015 DOI: 10.1002/Mrc.2250 |
0.507 |
|
| 2008 |
da Silva Júnior EN, de Souza MCBV, Fernandes MC, Menna-Barreto RFS, Pinto MdCFR, de Assis Lopes F, de Simone CA, Andrade CKZ, Pinto AV, Ferreira VF, de Castro SL. Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones Bioorganic and Medicinal Chemistry. 16: 5030-5038. PMID 18378461 DOI: 10.1016/J.Bmc.2008.03.032 |
0.569 |
|
| 2008 |
da Silva EN, Menna-Barreto RFS, Pinto MdCFR, Silva RSF, Teixeira DV, de Souza MCBV, De Simone CA, De Castro SL, Ferreira VF, Pinto AV. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi European Journal of Medicinal Chemistry. 43: 1774-1780. PMID 18045742 DOI: 10.1016/J.Ejmech.2007.10.015 |
0.568 |
|
| 2007 |
da Silva Júnior EN, de Souza MC, Pinto AV, Pinto Mdo C, Goulart MO, Barros FW, Pessoa C, Costa-Lotufo LV, Montenegro RC, de Moraes MO, Ferreira VF. Synthesis and potent antitumor activity of new arylamino derivatives of nor-beta-lapachone and nor-alpha-lapachone. Bioorganic & Medicinal Chemistry. 15: 7035-41. PMID 17827021 DOI: 10.1016/J.Bmc.2007.07.043 |
0.549 |
|
| 2007 |
Silva RS, Leitão GG, Brum TB, Lobato AP, Pinto Mdo C, Pinto AV. Applications of counter-current chromatography in organic synthesis purification of heterocyclic derivatives of lapachol. Journal of Chromatography. A. 1151: 197-202. PMID 17408681 DOI: 10.1016/J.Chroma.2007.03.066 |
0.314 |
|
| 2007 |
Carvalho CEM, Pinto AV, Harrison WTA. 3-Bromo-6-phenylhydrazono-β-lapachone Acta Crystallographica Section E Structure Reports Online. 63: o4504-o4504. DOI: 10.1107/S1600536807053810 |
0.311 |
|
| 2007 |
Nunes IKdC, Simone CAD, Silva RSF, Pinto AV, Goulart MOF. 14b‐Chloro‐4a‐methoxy‐3,3‐dimethyl‐2,3,4a,14b‐tetrahydro‐1H‐benzo[a]pyrano[2,3‐c]phenazine: a new active structural type against Mycobacterium tuberculosis Acta Crystallographica Section E: Crystallographic Communications. 63. DOI: 10.1107/S1600536807033259 |
0.374 |
|
| 2007 |
da Silva MN, Ferreira SB, Jorqueira A, de Souza MCBV, Pinto AV, Kaiser CR, Ferreira VF. Synthesis of new carbonyl and fluoroalkyl o-quinone methides from β-lapachone Tetrahedron Letters. 48: 6171-6173. DOI: 10.1016/J.Tetlet.2007.06.145 |
0.477 |
|
| 2006 |
Ferreira VF, Jorqueira A, Souza AM, da Silva MN, de Souza MC, Gouvêa RM, Rodrigues CR, Pinto AV, Castro HC, Santos DO, Araújo HP, Bourguignon SC. Trypanocidal agents with low cytotoxicity to mammalian cell line: a comparison of the theoretical and biological features of lapachone derivatives. Bioorganic & Medicinal Chemistry. 14: 5459-66. PMID 16725327 DOI: 10.1016/J.Bmc.2006.04.046 |
0.532 |
|
| 2006 |
Silva RSF, Costa EM, Trindade ÚLT, Teixeira DV, Pinto MdCFR, Santos GL, Malta VRS, Simone CAD, Pinto AV, Castro SLd. Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi. European Journal of Medicinal Chemistry. 41: 526-530. PMID 16500733 DOI: 10.1016/J.Ejmech.2005.12.006 |
0.416 |
|
| 2006 |
Ferreira VF, Jorqueira A, Leal KZ, Pimentel HR, Seidl PR, da Silva MN, da Souza MC, Pinto AV, Wardell JL, Wardell SM. Preparation of alpha-diazocarbonyl compounds from beta-lapachone derivatives and other 1,2-naphthoquinones: use of the 2D NMR 1H,15N and 1H,13C HMBC techniques in assigning regiochemistry. Magnetic Resonance in Chemistry : Mrc. 44: 481-90. PMID 16489549 DOI: 10.1002/Mrc.1778 |
0.511 |
|
| 2006 |
Simone CAD, Silva RP, Goulart MOF, Silva RSF, Lobato APG, Pinto MdCFR, Pinto AV. Synthesis and crystal structure of the N4-oxide of an hydroxybenzo(f)quinoxalin-6(5H)-one obtained by oxidative cleavage of beta-lapachone-quinoxaline Journal of Chemical Crystallography. 36: 551-556. DOI: 10.1007/S10870-006-9097-1 |
0.306 |
|
| 2005 |
Menna-Barreto RF, Henriques-Pons A, Pinto AV, Morgado-Diaz JA, Soares MJ, De Castro SL. Effect of a beta-lapachone-derived naphthoimidazole on Trypanosoma cruzi: identification of target organelles. The Journal of Antimicrobial Chemotherapy. 56: 1034-41. PMID 16269551 DOI: 10.1093/Jac/Dki403 |
0.345 |
|
| 2005 |
Silva RSF, Guimarães TT, Teixeira DV, Lobato APG, Pinto MdCFR, Simone CAd, Soares JG, Cioletti AG, Goulart MOF, Pinto AV. The preparation of a 10-membered ring macrolactone by selective ozonolysis and the role of the dihydropyran-substituent on the MCPBA-oxidation reaction profile of beta-lapachone phenazines Journal of the Brazilian Chemical Society. 16: 1074-1077. DOI: 10.1590/S0103-50532005000600027 |
0.328 |
|
| 2004 |
De Moura KC, Salomão K, Menna-Barreto RF, Emery FS, Pinto Mdo C, Pinto AV, de Castro SL. Studies on the trypanocidal activity of semi-synthetic pyran[b-4,3]naphtho[1,2-d]imidazoles from beta-lapachone. European Journal of Medicinal Chemistry. 39: 639-45. PMID 15236845 DOI: 10.1016/J.Ejmech.2004.02.015 |
0.393 |
|
| 2004 |
Goulart MO, Machado Reys JR, Emery FS, Pinto AV, de Souza Filho JD. NMR characterization of new 10-membered-ring macrolactones and dihydrobenzophenazine-5-one, oxidized derivatives of benzo[a]phenazines. Magnetic Resonance in Chemistry : Mrc. 42: 663-5. PMID 15181638 DOI: 10.1002/Mrc.1395 |
0.353 |
|
| 2004 |
de Andrade-Neto VF, Goulart MO, da Silva Filho JF, da Silva MJ, Pinto Mdo C, Pinto AV, Zalis MG, Carvalho LH, Krettli AU. Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo. Bioorganic & Medicinal Chemistry Letters. 14: 1145-9. PMID 14980653 DOI: 10.1016/J.Bmcl.2003.12.069 |
0.318 |
|
| 2004 |
Carvalho CEM, Lucas NCd, Herrera JOM, Pinto AV, Pinto MCFR, Brinn IM. Fluorescent symmetric phenazines from naphthoquinones: 4. Solvent effect on time-resolved fluorescence Journal of Photochemistry and Photobiology a-Chemistry. 167: 1-9. DOI: 10.1016/J.Jphotochem.2004.03.024 |
0.309 |
|
| 2003 |
Silva MNd, Souza MCBVd, Ferreira VF, Pinto AV, Pinto MdCRF, Wardell SMSV, Wardell JL. Synthesis of new aldehyde derivatives from β-lapachone and nor-β-lapachone Arkivoc. 2003. DOI: 10.3998/Ark.5550190.0004.A16 |
0.489 |
|
| 2003 |
Malta VRS, Pinto AV, Molfetta FA, Honório KM, De Simone CA, Pereira MA, Santos RHA, Da Silva ABF. The influence of electronic and steric effects in the structure-activity relationship (SAR) study of quinone compounds with biological activity against Trypanosoma cruzi Journal of Molecular Structure: Theochem. 634: 271-280. DOI: 10.1016/S0166-1280(03)00379-8 |
0.351 |
|
| 2003 |
Goulart MOF, Cioletti AG, Filho JDdS, Simone CAD, Castellano EE, Emery FS, Moura KCGD, Pinto MCFR, Pinto AV. Unexpected oxidation of a substituted benzo(a)phenazine: oxidative cleavage of a double bond and formation of a macrolactone Tetrahedron Letters. 44: 3581-3585. DOI: 10.1016/S0040-4039(03)00605-1 |
0.354 |
|
| 2002 |
Ferreira VF, Pinto AV, Pinto MC, da Silva MN, Skakle JM, de Souza MC, Wardell SM. 2,3-Dihydro-3,3-dimethylspiro[1H-4-oxanthracene-5,2'-oxiran]-10(5H)-one. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o560-2. PMID 12205388 DOI: 10.1107/S0108270102013665 |
0.492 |
|
| 2002 |
Neves-Pinto C, Malta VRS, Pinto MDCFR, Santos RHA, Castro SLD, Pinto AV. A Trypanocidal Phenazine Derived from β-Lapachone Journal of Medicinal Chemistry. 45: 2112-2115. PMID 11985478 DOI: 10.1021/Jm010377V |
0.337 |
|
| 2002 |
Lima NMF, Correia CS, Ferraz PAL, Pinto AV, Pinto MdCRF, Santana AEG, Goulart MOF. Molluscicidal hydroxynaphthoquinones and derivatives: correlation between their redox potentials and activity against Biomphalaria glabrata Journal of the Brazilian Chemical Society. 13: 822-829. DOI: 10.1590/S0103-50532002000600015 |
0.33 |
|
| 2002 |
Simone CAD, Malta VRS, Pereira MA, Bispo JRS, Pinto AV, Pinto MCFR. 3‐Bromo‐β‐lapachone Acta Crystallographica Section E-Structure Reports Online. 58. DOI: 10.1107/S1600536802001265 |
0.344 |
|
| 2002 |
Carvalho CEM, Ferreira VF, Pinto AV, Pinto MdCFR, Harrison W. Heterocyclic derivatives from natural occurring naphthoquinones: synthesis, characterization and X-ray structure of beta-lapachone hydrazo compounds Dyes and Pigments. 52: 209-214. DOI: 10.1016/S0143-7208(01)00097-3 |
0.513 |
|
| 2001 |
Moura KCGD, Emery FS, Neves-Pinto C, Pinto MdCFR, Dantas AP, Salomão K, Castro SLd, Pinto AV. Trypanocidal Activity of Isolated Naphthoquinones from Tabebuia and Some Heterocyclic Derivatives: A Review from an Interdisciplinary Study Journal of the Brazilian Chemical Society. 12: 325-338. DOI: 10.1590/S0103-50532001000300003 |
0.366 |
|
| 2000 |
dos Santos AF, Ferraz PA, Pinto AV, Pinto M do C, Goulart MO, Sant'Ana AE. Molluscicidal activity of 2-hydroxy-3-alkyl-1,4-naphthoquinones and derivatives. International Journal For Parasitology. 30: 1199-202. PMID 11027788 DOI: 10.1016/S0020-7519(00)00114-4 |
0.302 |
|
| 1992 |
Silva JS, Ferrioli-Filho S, Kanesiro MM, Ferreira VF, Santos SC, Pinto CN, Fonseca JL, Mizrahy HE, Gilbert B, Pinto MCFR, Ribeiro FW, Pinto AV. Evaluation of some organic compounds on bloodstream forms of Trypanosoma cruzi. Memorias Do Instituto Oswaldo Cruz. 87: 345-351. PMID 1343643 DOI: 10.1590/S0074-02761992000300003 |
0.371 |
|
| 1989 |
Ferreira VF, Pinto AV, Pinto MCFR, Cruz MCD, Clarino A. An Easy Approach to Prepare Naphtho [−2, 3-b] Furan-4, 9-diones Synthetic Communications. 19: 1061-1069. DOI: 10.1080/00397918908051029 |
0.473 |
|
| 1985 |
Pinto AV, Ferreira VF, Pinto MCFR, Mayer LU. Reaction of 2-Amino-1,4-Naphthoquinone Derivatives with Dimethyl Acetylenedicarboxylate Synthetic Communications. 15: 1181-1189. DOI: 10.1080/00397918508077263 |
0.39 |
|
| 1985 |
Pinto AV, Ferreira VF, Pinto MDCFR. Oxidation with DMF/HIO4. A Convenient Preparation of Juglone (I). Cheminform. 17: 1177-1180. DOI: 10.1002/Chin.198611186 |
0.349 |
|
| 1984 |
Lopes CC, Lopes RSC, Pinto AV, Costa PRR. Efficient synthesis of cytotoxic quinones: 2‐Acetyl‐4H,9H‐naphtho[2,3‐b]furan‐4,9‐dione (6) and (±)‐2‐(1‐hydroxyethyl)‐4H,9H‐naphtho[2,3‐b]furan‐4,9‐dione (7) Journal of Heterocyclic Chemistry. 21: 621-622. DOI: 10.1002/Jhet.5570210274 |
0.328 |
|
| 1982 |
Ferreira VF, Coutada LC, Pinto MCFR, Pinto AV. A Novel Synthesis of α and β -Pyran-naphthoquin one Tetracyclic Synthetic Communications. 12: 195-199. DOI: 10.1080/00397918208063677 |
0.317 |
|
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