Ramasamy Paulmurugan - Publications

Affiliations: 
Radiology Stanford University, Palo Alto, CA 

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bose RJ, Kumar SU, Zeng Y, Afjei R, Robinson E, Lau K, Bermudez A, Habte F, Pitteri SJ, Sinclair R, Willmann JK, Massoud TF, Gambhir SS, Paulmurugan R. Correction to "Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents". Acs Nano. PMID 37721437 DOI: 10.1021/acsnano.3c08363  0.806
2023 Sukumar UK, Rajendran JCB, Gambhir SS, Massoud TF, Paulmurugan R. Correction to "SP94-Targeted Triblock Copolymer Nanoparticle Delivers Thymidine Kinase-p53-Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in Vivo". Acs Applied Materials & Interfaces. PMID 37605509 DOI: 10.1021/acsami.3c09905  0.79
2023 Kumar US, Afjei R, Ferrara K, Massoud TF, Paulmurugan R. Correction to "Gold-Nanostar-Chitosan-Mediated Delivery of SARS-CoV-2 DNA Vaccine for Respiratory Mucosal Immunization: Development and Proof-of-Principle". Acs Nano. PMID 37582219 DOI: 10.1021/acsnano.3c07103  0.487
2023 Bam R, Natarajan A, Tabesh F, Paulmurugan R, Dahl JJ. Synthesis and Evaluation of Clinically Translatable Targeted Microbubbles Using a Microfluidic Device for In Vivo Ultrasound Molecular Imaging. International Journal of Molecular Sciences. 24. PMID 37240396 DOI: 10.3390/ijms24109048  0.734
2023 Pandurangi RS, Sekar TV, Paulmurugan R. Restoration of the Lost Human Beta Defensin (hBD-1) in Cancer as a Strategy to Improve the Efficacy of Chemotherapy. Biorxiv : the Preprint Server For Biology. PMID 37066380 DOI: 10.1101/2023.04.03.535411  0.719
2022 Afjei R, Sadeghipour N, Kumar SU, Pandrala M, Kumar V, Malhotra SV, Massoud TF, Paulmurugan R. A New Nrf2 Inhibitor Enhances Chemotherapeutic Effects in Glioblastoma Cells Carrying p53 Mutations. Cancers. 14. PMID 36551609 DOI: 10.3390/cancers14246120  0.564
2022 Warren I, Moeller MM, Guiggey D, Chiang A, Maloy M, Ogoke O, Groth T, Mon T, Meamardoost S, Liu X, Thompson S, Szeglowski A, Thompson R, Chen P, Paulmurugan R, et al. FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22652. PMID 36515690 DOI: 10.1096/fj.202101506RRR  0.708
2022 Liu Y, Sukumar UK, Jugniot N, Seetharam SM, Rengaramachandran A, Sadeghipour N, Mukherjee P, Krishnan A, Massoud TF, Paulmurugan R. Inhaled Gold Nano-star Carriers for Targeted Delivery of Triple Suicide Gene Therapy and Therapeutic MicroRNAs to Lung Metastases: Development and Validation in a Small Animal Model. Advanced Therapeutics. 5. PMID 36212523 DOI: 10.1002/adtp.202200018  0.801
2022 Kim SB, Hori SS, Sadeghipour N, Sukumar UK, Paulmurugan R. Compact Eight-Channel Light-Sensing System for Bioassays. Methods in Molecular Biology (Clifton, N.J.). 2525: 377-386. PMID 35836084 DOI: 10.1007/978-1-0716-2473-9_29  0.766
2022 Paulmurugan R, Liu Y, Sukumar UK, Kanada M, Massoud TF. BRET Sensors for Imaging Membrane Integrity of Microfluidically Generated Extracellular Vesicles. Methods in Molecular Biology (Clifton, N.J.). 2525: 227-238. PMID 35836072 DOI: 10.1007/978-1-0716-2473-9_17  0.786
2022 Sadeghipour N, Kumar SU, Massoud TF, Paulmurugan R. A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models. Scientific Reports. 12: 12017. PMID 35835978 DOI: 10.1038/s41598-022-16219-x  0.552
2022 Jugniot N, Massoud TF, Dahl JJ, Paulmurugan R. Biomimetic nanobubbles for triple-negative breast cancer targeted ultrasound molecular imaging. Journal of Nanobiotechnology. 20: 267. PMID 35689262 DOI: 10.1186/s12951-022-01484-9  0.623
2022 Paulmurugan R, Malhotra M, Massoud ZT, Massoud TF. Correction to: The protean world of non-coding RNAs in glioblastoma. Journal of Molecular Medicine (Berlin, Germany). 100: 1093. PMID 35648188 DOI: 10.1007/s00109-022-02211-5  0.46
2022 Kumar US, Natarajan A, Massoud TF, Paulmurugan R. FN3 linked nanobubbles as a targeted contrast agent for US imaging of cancer-associated human PD-L1. Journal of Controlled Release : Official Journal of the Controlled Release Society. 346: 317-327. PMID 35469983 DOI: 10.1016/j.jconrel.2022.04.030  0.573
2022 Wang H, Vilches-Moure JG, Bettinger T, Cherkaoui S, Lutz A, Paulmurugan R. Contrast Enhanced Ultrasound Molecular Imaging of Spontaneous Chronic Inflammatory Bowel Disease in an Interleukin-2 Receptor α Transgenic Mouse Model Using Targeted Microbubbles. Nanomaterials (Basel, Switzerland). 12. PMID 35055297 DOI: 10.3390/nano12020280  0.604
2022 Wang H, Hu Z, Sukumar UK, Bose RJ, Telichko A, Dahl JJ, Paulmurugan R. Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma. Nanotheranostics. 6: 62-78. PMID 34976581 DOI: 10.7150/ntno.63320  0.775
2021 Liu Y, Sukumar UK, Kanada M, Krishnan A, Massoud TF, Paulmurugan R. Camouflaged Hybrid Cancer Cell-Platelet Fusion Membrane Nanovesicles Deliver Therapeutic MicroRNAs to Presensitize Triple-Negative Breast Cancer to Doxorubicin. Advanced Functional Materials. 31. PMID 34899115 DOI: 10.1002/adfm.202103600  0.802
2021 Bose RJ, Kumar US, Garcia-Marques F, Zeng Y, Habte F, McCarthy JR, Pitteri S, Massoud TF, Paulmurugan R. Engineered Cell-Derived Vesicles Displaying Targeting Peptide and Functionalized with Nanocarriers for Therapeutic microRNA Delivery to Triple-Negative Breast Cancer in Mice. Advanced Healthcare Materials. e2101387. PMID 34879180 DOI: 10.1002/adhm.202101387  0.796
2021 Jugniot N, Bam R, Paulmurugan R. Expression and purification of a native Thy1-single-chain variable fragment for use in molecular imaging. Scientific Reports. 11: 23026. PMID 34845270 DOI: 10.1038/s41598-021-02445-2  0.738
2021 Ali R, Telichko AV, Wang H, Sukumar UK, Vilches-Moure JG, Paulmurugan R, Dahl JJ. Local Sound Speed Estimation for Pulse-Echo Ultrasound in Layered Media. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. PMID 34723801 DOI: 10.1109/TUFFC.2021.3124479  0.687
2021 Wang K, Kumar US, Sadeghipour N, Massoud TF, Paulmurugan R. A Microfluidics-Based Scalable Approach to Generate Extracellular Vesicles with Enhanced Therapeutic MicroRNA Loading for Intranasal Delivery to Mouse Glioblastomas. Acs Nano. PMID 34723509 DOI: 10.1021/acsnano.1c07587  0.549
2021 Kumar US, Afjei R, Ferrara K, Massoud TF, Paulmurugan R. Gold-Nanostar-Chitosan-Mediated Delivery of SARS-CoV-2 DNA Vaccine for Respiratory Mucosal Immunization: Development and Proof-of-Principle. Acs Nano. PMID 34705425 DOI: 10.1021/acsnano.1c05002  0.504
2021 Sukumar UK, Habte F, Massoud TF, Paulmurugan R. High-Throughput Whole-Plate Imaging of Cells for Multiple Biological Applications. Methods in Molecular Biology (Clifton, N.J.). 2274: 367-384. PMID 34050486 DOI: 10.1007/978-1-0716-1258-3_30  0.812
2021 Robinson ER, Gowrishankar G, D'Souza A, Kheirolomoom A, Haywood T, Hori SS, Chuang HY, Zeng Y, Tumbale S, Aalipour A, Beinat C, Alam IS, Sathirachinda A, Kanada M, Paulmurugan R, et al. Minicircles for a two-step blood biomarker and PET imaging early cancer detection strategy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34029631 DOI: 10.1016/j.jconrel.2021.05.026  0.813
2021 Peterson KM, Franchi F, Olthoff M, Paulmurugan R, Rodriguez-Porcel M. Cardio Phenotypic Potential of Mesenchymal Stem Cells. Current Protocols. 1: e62. PMID 33661576 DOI: 10.1002/cpz1.62  0.566
2021 Jugniot N, Bam R, Meuillet EJ, Unger EC, Paulmurugan R. Current status of targeted microbubbles in diagnostic molecular imaging of pancreatic cancer. Bioengineering & Translational Medicine. 6: e10183. PMID 33532585 DOI: 10.1002/btm2.10183  0.737
2021 Min S, Ko MJ, Jung HJ, Kim W, Han SB, Kim Y, Bae G, Lee S, Thangam R, Choi H, Li N, Shin JE, Jeon YS, Park HS, Kim YJ, ... ... Paulmurugan R, et al. Remote Control of Time-Regulated Stretching of Ligand-Presenting Nanocoils In Situ Regulates the Cyclic Adhesion and Differentiation of Stem Cells. Advanced Materials (Deerfield Beach, Fla.). e2008353. PMID 33527502 DOI: 10.1002/adma.202008353  0.728
2020 Bose RJC, Tharmalingam N, Choi Y, Madheswaran T, Paulmurugan R, McCarthy JR, Lee SH, Park H. Combating Intracellular Pathogens with Nanohybrid-Facilitated Antibiotic Delivery. International Journal of Nanomedicine. 15: 8437-8449. PMID 33162754 DOI: 10.2147/IJN.S271850  0.713
2020 Liu Y, Wang K, Massoud TF, Paulmurugan R. SARS-CoV-2 Vaccine Development: An Overview and Perspectives. Acs Pharmacology & Translational Science. 3: 844-858. PMID 33062951 DOI: 10.1021/acsptsci.0c00109  0.485
2020 Olthoff M, Franchi F, Peterson KM, Paulmurugan R, Rodriguez-Porcel M. Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model. Journal of Visualized Experiments : Jove. PMID 32955500 DOI: 10.3791/61546  0.637
2020 Bam R, Daryaei I, Abou-Elkacem L, Vilches-Moure JG, Meuillet EJ, Lutz A, Marinelli ER, Unger EC, Gambhir SS, Paulmurugan R. Toward the Clinical Development and Validation of a Thy1-Targeted Ultrasound Contrast Agent for the Early Detection of Pancreatic Ductal Adenocarcinoma. Investigative Radiology. PMID 32569010 DOI: 10.1097/Rli.0000000000000697  0.798
2020 Bose RJ, Tharmalingam N, Garcia Marques FJ, Sukumar UK, Natarajan A, Zeng Y, Robinson E, Bermudez A, Chang E, Habte F, Pitteri SJ, McCarthy J, Gambhir SS, Massoud TF, Mylonakis E, ... Paulmurugan R, et al. Reconstructed Apoptotic Bodies as Targeted 'Nano Decoys' to Treat Intracellular Bacterial Infections within Macrophages and Cancer Cells. Acs Nano. PMID 32347709 DOI: 10.1021/Acsnano.0C00921  0.79
2020 Kim SB, Hori SS, Sadeghipour N, Sukumar UK, Fujii R, Massoud TF, Paulmurugan R. Highly sensitive eight-channel light sensing system for biomedical applications. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 32159572 DOI: 10.1039/D0Pp00017E  0.782
2020 Peterson KM, Franchi F, Olthoff M, Chen IY, Paulmurugan R, Rodriguez-Porcel M. Pathway-specific reporter genes to study stem cell biology. Stem Cells (Dayton, Ohio). PMID 32129537 DOI: 10.1002/Stem.3167  0.747
2020 Sukumar UK, Rajendran JCB, Gambhir SS, Massoud TF, Paulmurugan R. SP94-Targeted Triblock Co-Polymer Nanoparticle Delivers Thymidine Kinase-p53-Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in vivo. Acs Applied Materials & Interfaces. PMID 32048820 DOI: 10.1021/Acsami.9B20071  0.812
2020 Wischhusen JC, Chowdhury SM, Lee T, Wang H, Bachawal S, Devulapally R, Afjei R, Sukumar UK, Paulmurugan R. Ultrasound-mediated delivery of miRNA-122 and anti-miRNA-21 therapeutically immunomodulates murine hepatocellular carcinoma in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32004588 DOI: 10.1016/J.Jconrel.2020.01.051  0.782
2020 Bam R, Lown PS, Stern LA, Sharma K, Wilson KE, Bean GR, Lutz AM, Paulmurugan R, Hackel BJ, Dahl J, Abou-Elkacem L. Efficacy of affibody-based ultrasound molecular imaging of vascular B7-H3 for breast cancer detection. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31924738 DOI: 10.1158/1078-0432.Ccr-19-1655  0.796
2020 Franchi F, Ramaswamy V, Olthoff M, Peterson KM, Paulmurugan R, Rodriguez-Porcel M. The Myocardial Microenvironment Modulates the Biology of Transplanted Mesenchymal Stem Cells. Molecular Imaging and Biology. PMID 31907845 DOI: 10.1007/S11307-019-01470-Y  0.633
2019 Bose RJ, Kim M, Chang JH, Paulmurugan R, Moon JJ, Koh WG, Lee SH, Park H. Biodegradable polymers for modern vaccine development. Journal of Industrial and Engineering Chemistry (Seoul, Korea). 77: 12-24. PMID 32288512 DOI: 10.1016/J.Jiec.2019.04.044  0.681
2019 Bae Kim S, Fujii R, Natarajan A, Massoud TF, Paulmurugan R. Ligand-activated BRET9 imaging for measuring protein-protein interactions in living mice. Chemical Communications (Cambridge, England). PMID 31807738 DOI: 10.1039/C9Cc07634D  0.582
2019 Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, ... ... Paulmurugan R, et al. Evaluation of integrin αvβ cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nature Communications. 10: 4673. PMID 31611594 DOI: 10.1038/S41467-019-11863-W  0.778
2019 Wang H, Vilches-Moure JG, Cherkaoui S, Tardy I, Alleaume C, Bettinger T, Lutz A, Paulmurugan R. Chronic Model of Inflammatory Bowel Disease in IL-10 Transgenic Mice: Evaluation with Ultrasound Molecular Imaging. Theranostics. 9: 6031-6046. PMID 31534535 DOI: 10.7150/Thno.37397  0.634
2019 Kanada M, Kim BD, Hardy JW, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH, Ronald JA. Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy. Molecular Cancer Therapeutics. PMID 31451563 DOI: 10.1158/1535-7163.Mct-19-0299  0.737
2019 Sukumar UK, Bose RJC, Malhotra M, Babikir HA, Afjei R, Robinson E, Zeng Y, Chang E, Habte F, Sinclair R, Gambhir SS, Massoud TF, Paulmurugan R. Intranasal delivery of targeted polyfunctional gold-iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and presensitization of glioblastoma to temozolomide. Biomaterials. 218: 119342. PMID 31326657 DOI: 10.1016/J.Biomaterials.2019.119342  0.808
2019 Di Ianni T, Bose RJC, Sukumar UK, Bachawal S, Wang H, Telichko A, Herickhoff C, Robinson E, Baker S, Vilches-Moure JG, Felt SA, Gambhir SS, Paulmurugan R, Dahl JD. Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31326463 DOI: 10.1016/J.Jconrel.2019.07.024  0.799
2019 Gupta N, Renugopalakrishnan V, Liepmann D, Paulmurugan R, Malhotra BD. Cell-based biosensors: Recent trends, challenges and future perspectives. Biosensors & Bioelectronics. 141: 111435. PMID 31238280 DOI: 10.1016/J.Bios.2019.111435  0.329
2019 Nishihara R, Paulmurugan R, Nakajima T, Yamamoto E, Natarajan A, Afjei R, Hiruta Y, Iwasawa N, Nishiyama S, Citterio D, Sato M, Kim SB, Suzuki K. Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events . Theranostics. 9: 2646-2661. PMID 31131059 DOI: 10.7150/Thno.32219  0.388
2019 Paulmurugan R, Malhotra M, Massoud TF. The protean world of non-coding RNAs in glioblastoma. Journal of Molecular Medicine (Berlin, Germany). PMID 31129756 DOI: 10.1007/S00109-019-01798-6  0.576
2019 Kim SB, Fujii R, Nishihara R, Bose RJC, Citterio D, Suzuki K, Massoud TF, Paulmurugan R. Molecular imaging of retinoic acids in live cells using single-chain bioluminescence probes. Acs Combinatorial Science. PMID 31034200 DOI: 10.1021/Acscombsci.9B00035  0.772
2019 Babikir H, Afjei R, Paulmurugan R, Massoud T. EXTH-30. PRECEDING p53 STABILIZATION USING DOXORUBICIN AUGMENTS PRIMA-1-MEDIATED p53 REFOLDING AND INCREASED CELLULAR APOPTOSIS: EVALUATION OF A SEQUENTIAL COMBINATION THERAPY AGAINST GLIOBLASTOMA Neuro-Oncology. 21: vi88-vi88. DOI: 10.1093/Neuonc/Noz175.362  0.614
2019 Sukumar U, Afjei R, Massoud T, Paulmurugan R. EXTH-28. TARGETED POLYGIONS ENGINEERED WITH SURFACE miRNAs FOR COMBINED MULTIMODALITY IMAGING AND ENHANCEMENT OF TEMOZOLOMIDE TREATMENT: A NOVEL INTRANASALLY-DELIVERED THERANOSTIC STRATEGY AGAINST GLIOBLASTOMA Neuro-Oncology. 21: vi87-vi88. DOI: 10.1093/Neuonc/Noz175.360  0.831
2018 Kumar N, Afjei R, Massoud TF, Paulmurugan R. Comparison of cell-based assays to quantify treatment effects of anticancer drugs identifies a new application for Bodipy-L-cystine to measure apoptosis. Scientific Reports. 8: 16363. PMID 30397244 DOI: 10.1038/S41598-018-34696-X  0.603
2018 Jc Bose R, Uday Kumar S, Zeng Y, Afjei R, Robinson E, Lau K, Bermudez A, Habte F, Pitteri SJ, Sinclair R, Willmann JK, Massoud TF, Gambhir SS, Paulmurugan R. Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents. Acs Nano. PMID 30346694 DOI: 10.1021/Acsnano.8B02587  0.818
2018 Babikir HA, Afjei R, Paulmurugan R, Massoud TF. Restoring guardianship of the genome: Anticancer drug strategies to reverse oncogenic mutant p53 misfolding. Cancer Treatment Reviews. 71: 19-31. PMID 30336366 DOI: 10.1016/J.Ctrv.2018.09.004  0.59
2018 Bose RJ, Kim BJ, Arai Y, Han IB, Moon JJ, Paulmurugan R, Park H, Lee SH. Bioengineered stem cell membrane functionalized nanocarriers for therapeutic targeting of severe hindlimb ischemia. Biomaterials. 185: 360-370. PMID 30273835 DOI: 10.1016/J.Biomaterials.2018.08.018  0.743
2018 Li K, Chan CT, Nejadnik H, Lenkov OD, Wolterman C, Paulmurugan R, Yang H, Gambhir SS, Daldrup-Link HE. Ferumoxytol-based Dual-modality Imaging Probe for Detection of Stem Cell Transplant Rejection. Nanotheranostics. 2: 306-319. PMID 29977742 DOI: 10.7150/ntno.26389  0.743
2018 Devulapally R, Lee T, Barghava-Shah A, Sekar TV, Foygel K, Bachawal SV, Willmann JK, Paulmurugan R. Ultrasound-guided delivery of thymidine kinase-nitroreductase dual therapeutic genes by PEGylated-PLGA/PIE nanoparticles for enhanced triple negative breast cancer therapy. Nanomedicine (London, England). PMID 29790803 DOI: 10.2217/Nnm-2017-0328  0.79
2018 Paulmurugan R, Afjei R, Sekar TV, Babikir HA, Massoud TF. A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells. Oncotarget. 9: 21495-21511. PMID 29765555 DOI: 10.18632/Oncotarget.25138  0.778
2018 Malhotra M, Sekar TV, Ananta JS, Devulapally R, Afjei R, Babikir HA, Paulmurugan R, Massoud TF. Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide and in a mouse model. Oncotarget. 9: 21478-21494. PMID 29765554 DOI: 10.18632/Oncotarget.25135  0.809
2018 Chowdhury SM, Lee T, Bachawal SV, Devulapally R, Abou-Elkacem L, Yeung TA, Wischhusen J, Tian L, Dahl J, Paulmurugan R, Willmann JK. Longitudinal assessment of ultrasound-guided complementary microRNA therapy of hepatocellular carcinoma. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29758233 DOI: 10.1016/J.Jconrel.2018.05.009  0.787
2018 Bose RJC, Paulmurugan R, Moon J, Lee SH, Park H. Cell membrane-coated nanocarriers: the emerging targeted delivery system for cancer theranostics. Drug Discovery Today. PMID 29426004 DOI: 10.1016/J.Drudis.2018.02.001  0.756
2017 Gaur S, Bhargava-Shah A, Hori S, Afjei R, Sekar TV, Gambhir SS, Massoud TF, Paulmurugan R. Engineering intracellularly retained Gaussia Luciferase reporters for improved biosensing and molecular imaging applications. Acs Chemical Biology. PMID 28767220 DOI: 10.1021/Acschembio.7B00454  0.798
2017 Hori SS, Lutz AM, Paulmurugan R, Gambhir SS. A model-based personalized cancer screening strategy for detecting early-stage tumors using blood-borne biomarkers. Cancer Research. PMID 28283654 DOI: 10.1158/0008-5472.Can-16-2904  0.794
2017 Malhotra M, Sekar T, Devulapally R, Afjei R, Paulmurugan R, Massoud T. EXTH-61. TARGETED NANOPARTICLE DELIVERY OF THERAPEUTIC ANTIMIR-21 AND ANTIMIR-10B PRESENSITIZES GLIOBLASTOMA TO LOWER EFFECTIVE DOSES OF TEMOZOLOMIDE IN CELLS AND XENOGRAFTS Neuro-Oncology. 19: vi86-vi86. DOI: 10.1093/Neuonc/Nox168.353  0.792
2017 Paulmurugan R, Afjei R, Babikir H, Sekar T, Massoud T. DDIS-16. A MOLECULAR IMAGING BIOSENSOR MONITORS THE EFFECTS OF ANTI-MISFOLDING DRUGS THAT RESTORE MUTANT p53 FUNCTION AND ENHANCE COMBINATION CHEMOTHERAPY FOR GLIOBLASTOMA Neuro-Oncology. 19: vi62-vi62. DOI: 10.1093/Neuonc/Nox168.251  0.777
2016 Devulapally R, Foygel K, Sekar TV, Willmann JK, Paulmurugan R. Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy. Acs Applied Materials & Interfaces. 8: 33412-33422. PMID 27960411 DOI: 10.1021/Acsami.6B08153  0.792
2016 Oronsky B, Paulmurugan R, Foygel K, Scicinski J, Knox SJ, Peehl D, Zhao H, Ning S, Cabrales P, Summers TA, Reid TR, Fitch WL, Kim MM, Trepel JB, Lee MJ, et al. RRx-001: A Systemically Non-Toxic M2-to-M1 Macrophage Stimulating and Prosensitizing Agent In Phase II Clinical Trials. Expert Opinion On Investigational Drugs. PMID 27935336 DOI: 10.1080/13543784.2017.1268600  0.737
2016 Sekar TV, Foygel K, Devulapally R, Kumar V, Malhotra S, Massoud TF, Paulmurugan R. Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice. Analytical Chemistry. 88: 11420-11428. PMID 27934110 DOI: 10.1021/Acs.Analchem.6B02048  0.797
2016 Calibasi Kocal G, Güven S, Foygel K, Goldman A, Chen P, Sengupta S, Paulmurugan R, Baskin Y, Demirci U. Dynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow. Scientific Reports. 6: 38221. PMID 27910892 DOI: 10.1038/Srep38221  0.731
2016 Sekar TV, Foygel K, Massoud TF, Gambhir SS, Paulmurugan R. A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling. Scientific Reports. 6: 34788. PMID 27721470 DOI: 10.1038/Srep34788  0.788
2016 Ananta JS, Paulmurugan R, Massoud TF. Tailored Nanoparticle Codelivery of antimiR-21 and antimiR-10b Augments Glioblastoma Cell Kill by Temozolomide: Toward a "Personalized" Anti-microRNA Therapy. Molecular Pharmaceutics. 13: 3164-75. PMID 27508339 DOI: 10.1021/Acs.Molpharmaceut.6B00388  0.587
2016 Chowdhury SM, Wang TY, Bachawal S, Devulapally R, Choe JW, Elkacem LA, Yakub BK, Wang DS, Tian L, Paulmurugan R, Willmann JK. Ultrasound-Guided Therapeutic Modulation of Hepatocellular Carcinoma using Complementary microRNAs. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27503707 DOI: 10.1016/J.Jconrel.2016.08.005  0.739
2016 Sekar TV, Paulmurugan R. Theranostic Imaging of Cancer Gene Therapy. Methods in Molecular Biology (Clifton, N.J.). 1461: 241-54. PMID 27424910 DOI: 10.1007/978-1-4939-3813-1_20  0.749
2016 Sekar TV, Paulmurugan R. Imaging Histone Methylations in Living Animals. Methods in Molecular Biology (Clifton, N.J.). 1461: 203-15. PMID 27424907 DOI: 10.1007/978-1-4939-3813-1_17  0.704
2016 Parashurama N, Ahn BC, Ziv K, Ito K, Paulmurugan R, Willmann JK, Chung J, Ikeno F, Swanson JC, Merk DR, Lyons JK, Yerushalmi D, Teramoto T, Kosuge H, Dao CN, et al. Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part II. In Vivo Imaging of Bone Marrow Stromal Cells in Swine with PET/CT and MR Imaging. Radiology. 151150. PMID 27332865 DOI: 10.1148/Radiol.2016151150  0.792
2016 Parashurama N, Ahn BC, Ziv K, Ito K, Paulmurugan R, Willmann JK, Chung J, Ikeno F, Swanson JC, Merk DR, Lyons JK, Yerushalmi D, Teramoto T, Kosuge H, Dao CN, et al. Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part I. Reporter Gene Design, Characterization, and Optical in Vivo Imaging of Bone Marrow Stromal Cells after Myocardial Infarction. Radiology. 140049. PMID 27308957 DOI: 10.1148/Radiol.2016140049  0.791
2016 Sheahan AV, Sekar TV, Chen K, Paulmurugan R, Massoud TF. A molecular imaging biosensor detects in vivo protein folding and misfolding. Journal of Molecular Medicine (Berlin, Germany). PMID 27277823 DOI: 10.1007/S00109-016-1437-9  0.781
2016 Ananta JS, Paulmurugan R, Massoud TF. Temozolomide-loaded PLGA nanoparticles to treat glioblastoma cells: a biophysical and cell culture evaluation. Neurological Research. 38: 51-9. PMID 26905383 DOI: 10.1080/01616412.2015.1133025  0.596
2016 Franchi F, Peterson KM, Paulmurugan R, Folmes C, Lanza IR, Lerman A, Rodriguez-Porcel M. Noninvasive Monitoring of the Mitochondrial Function in Mesenchymal Stromal Cells. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 26865378 DOI: 10.1007/S11307-016-0929-X  0.621
2016 Bhargava-Shah A, Foygel K, Devulapally R, Paulmurugan R. Orlistat and antisense-miRNA-loaded PLGA-PEG nanoparticles for enhanced triple negative breast cancer therapy. Nanomedicine (London, England). 11: 235-47. PMID 26787319 DOI: 10.2217/Nnm.15.193  0.794
2016 Kumar V, Foygel K, Paulmurugan R, Malhotra SV. Abstract 1363: Novel Nrf2 inhibitors and their application to overcome chemoresistance of anticancer drugs Cancer Research. 76: 1363-1363. DOI: 10.1158/1538-7445.Am2016-1363  0.696
2016 Franchi F, Peterson KM, Paulmurugan R, Folmes C, Lanza IR, Lerman A, Rodriguez-Porcel M. Noninvasive Monitoring of the Mitochondrial Function in Mesenchymal Stromal Cells Molecular Imaging and Biology. 1-9. DOI: 10.1007/s11307-016-0929-x  0.552
2015 Asghar W, El Assal R, Shafiee H, Pitteri S, Paulmurugan R, Demirci U. Engineering cancer microenvironments for in vitro 3-D tumor models. Materials Today (Kidlington, England). 18: 539-553. PMID 28458612 DOI: 10.1016/J.Mattod.2015.05.002  0.337
2015 Ananta JS, Paulmurugan R, Massoud TF. Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells. Molecular Pharmaceutics. 12: 4509-17. PMID 26559642 DOI: 10.1021/Acs.Molpharmaceut.5B00694  0.597
2015 Paulmurugan R, Bhethanabotla R, Mishra K, Devulapally R, Foygel K, Sekar TV, Ananta JS, Massoud TF, Joy A. Folate Receptor Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple Negative Breast Cancer. Molecular Cancer Therapeutics. PMID 26553061 DOI: 10.1158/1535-7163.Mct-15-0579  0.81
2015 Foygel K, Sekar TV, Paulmurugan R. Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy. Plos One. 10: e0141913. PMID 26536456 DOI: 10.1371/Journal.Pone.0141913  0.807
2015 Ning S, Sekar TV, Scicinski J, Oronsky B, Peehl DM, Knox SJ, Paulmurugan R. Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001. Oncotarget. 6: 21547-56. PMID 26280276 DOI: 10.18632/Oncotarget.4249  0.741
2015 Hwang GL, van den Bosch MA, Kim YI, Katzenberg R, Willmann JK, Paulmurugan R, Gambhir SS, Hofmann L. Development of a High-Throughput Molecular Imaging-Based Orthotopic Hepatocellular Carcinoma Model. CurēUs. 7: e281. PMID 26180705 DOI: 10.7759/Cureus.281  0.746
2015 Devulapally R, Sekar TV, Paulmurugan R. Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells. Molecular Pharmaceutics. 12: 2080-92. PMID 25880495 DOI: 10.1021/Mp500852S  0.801
2015 Wang TY, Choe JW, Pu K, Devulapally R, Bachawal S, Machtaler S, Chowdhury SM, Luong R, Tian L, Khuri-Yakub B, Rao J, Paulmurugan R, Willmann JK. Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 203: 99-108. PMID 25687306 DOI: 10.1016/J.Jconrel.2015.02.018  0.758
2015 Dou QQ, Rengaramchandran A, Selvan ST, Paulmurugan R, Zhang Y. Core-shell upconversion nanoparticle - semiconductor heterostructures for photodynamic therapy. Scientific Reports. 5: 8252. PMID 25652742 DOI: 10.1038/Srep08252  0.355
2015 Devulapally R, Sekar NM, Sekar TV, Foygel K, Massoud TF, Willmann JK, Paulmurugan R. Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy. Acs Nano. 9: 2290-302. PMID 25652012 DOI: 10.1021/Nn507465D  0.776
2015 Sekar TV, Foygel K, Gelovani JG, Paulmurugan R. Genetically encoded molecular biosensors to image histone methylation in living animals. Analytical Chemistry. 87: 892-9. PMID 25506787 DOI: 10.1021/Ac502629R  0.775
2015 Sekar TV, Foygel K, Devulapally R, Paulmurugan R. Degron protease blockade sensor to image epigenetic histone protein methylation in cells and living animals. Acs Chemical Biology. 10: 165-74. PMID 25489787 DOI: 10.1021/Cb5008037  0.79
2014 Chan CT, Qi J, Smith W, Paranol R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS. Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects. Cancer Research. 74: 7475-86. PMID 25320008 DOI: 10.1158/0008-5472.Can-14-0197  0.755
2014 Suganya N, Bhakkiyalakshmi E, Subin TS, Krishnamurthi K, Devi SS, Lau K, Sekar TV, Paulmurugan R, Ramkumar KM. Proteomic identification of pterostilbene-mediated anticancer activities in HepG2 cells. Chemical Research in Toxicology. 27: 1243-52. PMID 24936659 DOI: 10.1021/Tx5001392  0.709
2014 Ahn BC, Parashurama N, Patel M, Ziv K, Bhaumik S, Yaghoubi SS, Paulmurugan R, Gambhir SS. Noninvasive reporter gene imaging of human Oct4 (pluripotency) dynamics during the differentiation of embryonic stem cells in living subjects. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 865-76. PMID 24845530 DOI: 10.1007/S11307-014-0744-1  0.787
2014 Sekar TV, Foygel K, Ilovich O, Paulmurugan R. Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice. Theranostics. 4: 460-74. PMID 24669276 DOI: 10.7150/Thno.8077  0.817
2014 Bhakkiyalakshmi E, Shalini D, Sekar TV, Rajaguru P, Paulmurugan R, Ramkumar KM. Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2. British Journal of Pharmacology. 171: 1747-57. PMID 24417315 DOI: 10.1111/Bph.12577  0.691
2014 Devulapally R, Paulmurugan R. Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 6: 40-60. PMID 23996830 DOI: 10.1002/Wnan.1242  0.752
2014 Chen IY, Paulmurugan R, Nielsen CH, Wang DS, Chow V, Robbins RC, Gambhir SS. A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 224-34. PMID 23955099 DOI: 10.1007/S11307-013-0673-4  0.672
2014 Ning S, Sekar TV, Paulmurugan R, Scicinski J, Oronsky B, Peehl D, Knox SJ. Abstract 906: Molecular imaging of RRx-001-induced oxidative stress in Nrf2-luciferase expressing SCC VII tumors in mice Cancer Research. 74: 906-906. DOI: 10.1158/1538-7445.Am2014-906  0.76
2014 Hori SS, Lutz AM, Paulmurugan R, Gambhir SS. Abstract 873: Correlation of plasma biomarker levels with early-stage tumor viability in an orthotopic ovarian cancer mouse model Cancer Research. 74: 873-873. DOI: 10.1158/1538-7445.Am2014-873  0.513
2014 Foygel K, Sekar TV, Paulmurugan R. Abstract 5120: Monitoring antioxidant induced chemosensitization in triple negative breast cancer cells by Nrf2-luciferase fusion protein Cancer Research. 74: 5120-5120. DOI: 10.1158/1538-7445.Am2014-5120  0.814
2013 Sekar TV, Paulmurugan R. H-Penciclovir (H-PCV) Uptake Assay. Bio-Protocol. 3. PMID 27446976  0.705
2013 Sekar TV, Mohanram RK, Foygel K, Paulmurugan R. Therapeutic evaluation of microRNAs by molecular imaging. Theranostics. 3: 964-85. PMID 24396507 DOI: 10.7150/Thno.4928  0.802
2013 Paulmurugan R. MicroRNAs - a new generation molecular targets for treating cellular diseases. Theranostics. 3: 927-9. PMID 24396503 DOI: 10.7150/Thno.8113  0.342
2013 Yan X, Ray P, Paulmurugan R, Tong R, Gong Y, Sathirachinda A, Wu JC, Gambhir SS. A transgenic tri-modality reporter mouse. Plos One. 8: e73580. PMID 23951359 DOI: 10.1371/Journal.Pone.0073580  0.81
2013 Chen IY, Gheysens O, Li Z, Rasooly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel M, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS. Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia. Human Gene Therapy Methods. 24: 279-88. PMID 23937265 DOI: 10.1089/Hgtb.2013.028  0.797
2013 Ramkumar KM, Sekar TV, Foygel K, Elango B, Paulmurugan R. Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals. Analytical Chemistry. 85: 7542-9. PMID 23826874 DOI: 10.1021/Ac401569J  0.812
2013 Fan-Minogue H, Bodapati S, Solow-Cordero D, Fan A, Paulmurugan R, Massoud TF, Felsher DW, Gambhir SS. A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide. Molecular Cancer Therapeutics. 12: 1896-905. PMID 23825064 DOI: 10.1158/1535-7163.Mct-12-1243  0.794
2013 Paulmurugan R, Oronsky B, Brouse CF, Reid T, Knox S, Scicinski J. Real time dynamic imaging and current targeted therapies in the war on cancer: a new paradigm. Theranostics. 3: 437-47. PMID 23781290 DOI: 10.7150/Thno.5658  0.367
2013 Ramkumar KM, Sekar TV, Bhakkiyalakshmi E, Foygel K, Rajaguru P, Berger F, Paulmurugan R. The impact of oxidative stress on islet transplantation and monitoring the graft survival by non-invasive imaging. Current Medicinal Chemistry. 20: 1127-46. PMID 23317098 DOI: 10.2174/0929867311320090003  0.777
2012 Sekar TV, Foygel K, Willmann JK, Paulmurugan R. Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging. Gene Therapy. 20: 529-37. PMID 22914496 DOI: 10.1038/Gt.2012.66  0.815
2012 Chan CT, Reeves RE, Geller R, Yaghoubi SS, Hoehne A, Solow-Cordero DE, Chiosis G, Massoud TF, Paulmurugan R, Gambhir SS. Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects. Proceedings of the National Academy of Sciences of the United States of America. 109: E2476-85. PMID 22895790 DOI: 10.1073/Pnas.1205459109  0.793
2012 Wang DS, Panje C, Pysz MA, Paulmurugan R, Rosenberg J, Gambhir SS, Schneider M, Willmann JK. Cationic versus neutral microbubbles for ultrasound-mediated gene delivery in cancer. Radiology. 264: 721-32. PMID 22723497 DOI: 10.1148/Radiol.12112368  0.525
2012 Ramkumar KM, Manjula C, Gnanakumar G, Kanjwal MA, Sekar TV, Paulmurugan R, Rajaguru P. Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO2 nanofibers in HeLa cells. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 81: 324-33. PMID 22446064 DOI: 10.1016/J.Ejpb.2012.02.013  0.706
2012 Kim YI, Ahn BC, Ronald JA, Katzenberg R, Singh A, Paulmurugan R, Ray S, Gambhir SS, Hofmann LV. Intratumoral versus intravenous gene therapy using a transcriptionally targeted viral vector in an orthotopic hepatocellular carcinoma rat model. Journal of Vascular and Interventional Radiology : Jvir. 23: 704-11. PMID 22387029 DOI: 10.1016/J.Jvir.2012.01.053  0.801
2012 Paulmurugan R, Sekar NM, Sekar TV. Biodegradable polymer nanocarriers for therapeutic antisense microRNA delivery in living animals Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8232. DOI: 10.1117/12.914830  0.82
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Paulmurugan R, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.631
2011 Paulmurugan R, Tamrazi A, Massoud TF, Katzenellenbogen JA, Gambhir SS. In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. Molecular Endocrinology (Baltimore, Md.). 25: 2029-40. PMID 22052998 DOI: 10.1210/Me.2011-1145  0.63
2011 Bhaumik S, Sekar TV, Depuy J, Klimash J, Paulmurugan R. Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals. Gene Therapy. 19: 295-302. PMID 21753794 DOI: 10.1038/Gt.2011.101  0.758
2011 Thakor AS, Luong R, Paulmurugan R, Lin FI, Kempen P, Zavaleta C, Chu P, Massoud TF, Sinclair R, Gambhir SS. The fate and toxicity of Raman-active silica-gold nanoparticles in mice. Science Translational Medicine. 3: 79ra33. PMID 21508310 DOI: 10.1126/Scitranslmed.3001963  0.781
2011 Auer VJ, Bucher J, Schremmer-Danninger E, Paulmurugan R, Maechler P, Reiser MF, Stangl MJ, Berger F. Non-invasive imaging of ferucarbotran labeled INS-1E cells and rodent islets in vitro and in transplanted diabetic rats. Current Pharmaceutical Biotechnology. 12: 488-96. PMID 21342106 DOI: 10.2174/138920111795163878  0.677
2011 Sekar TV, Dhanabalan A, Paulmurugan R. Imaging cellular receptors in breast cancers: An overview Current Pharmaceutical Biotechnology. 12: 508-527. PMID 21342102 DOI: 10.2174/138920111795164039  0.718
2011 Ahn BC, Ronald JA, Kim YI, Katzenberg R, Singh A, Paulmurugan R, Ray S, Hofmann LV, Gambhir SS. Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector. Gene Therapy. 18: 606-12. PMID 21307888 DOI: 10.1038/gt.2011.5  0.747
2011 Gheysens O, Chen IY, Rodriguez-Porcel M, Chan C, Rasooly J, Vaerenberg C, Paulmurugan R, Willmann JK, Deroose C, Wu J, Gambhir SS. Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 1124-32. PMID 21267661 DOI: 10.1007/S11307-011-0471-9  0.794
2011 Thakor AS, Paulmurugan R, Kempen P, Zavaleta C, Sinclair R, Massoud TF, Gambhir SS. Oxidative stress mediates the effects of Raman-active gold nanoparticles in human cells. Small (Weinheim An Der Bergstrasse, Germany). 7: 126-36. PMID 21104804 DOI: 10.1002/Smll.201001466  0.794
2011 Wang D, Pysz M, Panje C, Paulmurugan R, Rosenberg J, Gambhir S, Schneider M, Willmann J. Abstract No. 19: Plasmid-bearing cationic microbubbles potentiate ultrasound-mediated transvascular gene delivery in cell culture and mouse tumor models Journal of Vascular and Interventional Radiology. 22: S12. DOI: 10.1016/J.Jvir.2011.01.021  0.323
2010 Fan-Minogue H, Cao Z, Paulmurugan R, Chan CT, Massoud TF, Felsher DW, Gambhir SS. Noninvasive molecular imaging of c-Myc activation in living mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15892-7. PMID 20713710 DOI: 10.1073/Pnas.1007443107  0.8
2010 Massoud TF, Paulmurugan R, Gambhir SS. A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nature Medicine. 16: 921-6. PMID 20639890 DOI: 10.1038/Nm.2185  0.667
2010 Chen IY, Gheysens O, Ray S, Wang Q, Padmanabhan P, Paulmurugan R, Loening AM, Rodriguez-Porcel M, Willmann JK, Sheikh AY, Nielsen CH, Hoyt G, Contag CH, Robbins RC, Biswal S, et al. Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy. Gene Therapy. 17: 827-38. PMID 20237511 DOI: 10.1038/Gt.2010.30  0.796
2010 Rodriguez-Porcel M, Gheysens O, Paulmurugan R, Chen IY, Peterson KM, Willmann JK, Wu JC, Zhu X, Lerman LO, Gambhir SS. Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 325-34. PMID 20013064 DOI: 10.1007/S11307-009-0274-4  0.79
2010 Massoud TF, Paulmurugan R, Chan C, Fan-Minogue H, Gambhir SS. Reporter gene imaging of cell signal transduction Molecular Imaging With Reporter Genes. 195-226. DOI: 10.1017/CBO9780511730405.009  0.789
2009 Paulmurugan R, Padmanabhan P, Ahn BC, Ray S, Willmann JK, Massoud TF, Biswal S, Gambhir SS. A novel estrogen receptor intramolecular folding-based titratable transgene expression system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1703-11. PMID 19654568 DOI: 10.1038/Mt.2009.171  0.789
2009 Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, et al. Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology. 252: 117-27. PMID 19366903 DOI: 10.1148/Radiol.2513081616  0.794
2009 Chan CT, Paulmurugan R, Reeves RE, Solow-Cordero D, Gambhir SS. Molecular imaging of phosphorylation events for drug development Molecular Imaging and Biology. 11: 144-158. PMID 19048345 DOI: 10.1007/S11307-008-0187-7  0.734
2009 Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 178-87. PMID 19034584 DOI: 10.1007/S11307-008-0182-Z  0.8
2008 Choi CY, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS, Giaccia AJ. Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice. Molecular Imaging. 7: 139-46. PMID 19123984  0.339
2008 Ray S, Paulmurugan R, Patel MR, Ahn BC, Wu L, Carey M, Gambhir SS. Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1848-56. PMID 18766175 DOI: 10.1038/Mt.2008.180  0.664
2008 Willmann JK, Lutz AM, Paulmurugan R, Patel MR, Chu P, Rosenberg J, Gambhir SS. Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology. 248: 936-44. PMID 18710985 DOI: 10.1148/Radiol.2483072231  0.764
2008 Berger F, Paulmurugan R, Bhaumik S, Gambhir SS. Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging. European Journal of Nuclear Medicine and Molecular Imaging. 35: 2275-85. PMID 18661130 DOI: 10.1007/S00259-008-0870-6  0.713
2008 Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MA, Puttaparthi K, Hu W, Elliott JL, Stuve O, Habib AA. The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway. Embo Reports. 9: 766-73. PMID 18566599 DOI: 10.1038/Embor.2008.102  0.321
2008 Paulmurugan R, Tamrazi A, Katzenellenbogen JA, Katzenellenbogen BS, Gambhir SS. A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Molecular Endocrinology (Baltimore, Md.). 22: 1552-64. PMID 18451095 DOI: 10.1210/Me.2007-0570  0.431
2008 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS. Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation. 117: 915-22. PMID 18250264 DOI: 10.1161/Circulationaha.107.733220  0.775
2008 Willmann JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology. 246: 508-18. PMID 18180339 DOI: 10.1148/Radiol.2462070536  0.812
2008 Chan CT, Paulmurugan R, Gheysens OS, Kim J, Chiosis G, Gambhir SS. Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects. Cancer Research. 68: 216-26. PMID 18172314 DOI: 10.1158/0008-5472.Can-07-2268  0.779
2008 Giaccia AJ, Choi CYH, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS. Molecular imaging of hypoxia-inducible factor 1α and von Hippel-Lindau interaction in mice Molecular Imaging. 7: 139-146. DOI: 10.2310/7290.2008.00017  0.432
2008 van den Bosch M, Higgens L, Hwang G, Katzenberg R, Willmann J, Paulmurugan R, Kuo W, Kothary N, Dan S, Gambhir S, Hofmann L. Abstract No. 372: A Novel Rat Hepatocellular Carcinoma Model Designed for In Vivo Evaluation of Image-Guided Therapies Journal of Vascular and Interventional Radiology. 19: S136-S137. DOI: 10.1016/J.Jvir.2007.12.429  0.448
2008 Higgins L, van den Bosch M, Hwang G, Paulmurugan R, Kothary N, Kuo W, Sze D, Katzenberg R, Gambhir S, Hofmann L. Abstract No. 368: In Vitro Transfection of Hepatoma Cells and Hepatocytes with a Nonviral Vector Using Protamine and Ethiodol Journal of Vascular and Interventional Radiology. 19: S135. DOI: 10.1016/J.Jvir.2007.12.425  0.326
2007 Paulmurugan R, Gambhir SS. Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions. Analytical Chemistry. 79: 2346-53. PMID 17295448 DOI: 10.1021/Ac062053Q  0.477
2007 Massoud TF, Paulmurugan R, De A, Ray P, Gambhir SS. Reporter gene imaging of protein-protein interactions in living subjects. Current Opinion in Biotechnology. 18: 31-7. PMID 17254764 DOI: 10.1016/J.Copbio.2007.01.007  0.786
2007 Lee P, Chan C, Hua A, Paulmurugan R, Chan D, Gambhir S, Le Q, Giaccia A. Noninvasive Monitoring of Ligand-Dependent VEGF Receptor-2 Dimerization With Split Firefly Luciferase International Journal of Radiation Oncology*Biology*Physics. 69: S96-S97. DOI: 10.1016/J.Ijrobp.2007.07.177  0.708
2006 Paulmurugan R, Gambhir SS. An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proceedings of the National Academy of Sciences of the United States of America. 103: 15883-8. PMID 17043219 DOI: 10.1073/Pnas.0607385103  0.481
2006 Padmanabhan P, Otero J, Ray P, Paulmurugan R, Hoffman AR, Gambhir SS, Biswal S, Ulaner GA. Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 270-7. PMID 16455633  0.729
2006 Krishnan M, Park JM, Cao F, Wang D, Paulmurugan R, Tseng JR, Gonzalgo ML, Gambhir SS, Wu JC. Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 106-8. PMID 16246867 DOI: 10.1096/Fj.05-4551Fje  0.782
2006 Choi C, Paulmurugan R, Chan D, Sutphin P, Le Q, Koong A, Gambhir S, Giaccia A. 83 International Journal of Radiation Oncology*Biology*Physics. 66: S48-S49. DOI: 10.1016/J.Ijrobp.2006.07.113  0.427
2005 Paulmurugan R, Gambhir SS. Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals. Cancer Research. 65: 7413-20. PMID 16103094 DOI: 10.1158/0008-5472.Can-05-0588  0.453
2005 Paulmurugan R, Gambhir SS. Firefly luciferase enzyme fragment complementation for imaging in cells and living animals. Analytical Chemistry. 77: 1295-302. PMID 15732910 DOI: 10.1021/Ac0484777  0.51
2004 Ray S, Paulmurugan R, Hildebrandt I, Iyer M, Wu L, Carey M, Gambhir SS. Novel bidirectional vector strategy for amplification of therapeutic and reporter gene expression. Human Gene Therapy. 15: 681-90. PMID 15242528 DOI: 10.1089/1043034041361271  0.669
2004 Massoud TF, Paulmurugan R, Gambhir SS. Molecular imaging of homodimeric protein-protein interactions in living subjects. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1105-7. PMID 15132989 DOI: 10.1096/Fj.03-1128Fje  0.674
2004 Paulmurugan R, Massoud TF, Huang J, Gambhir SS. Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Research. 64: 2113-9. PMID 15026351 DOI: 10.1158/0008-5472.Can-03-2972  0.667
2004 Sundaresan G, Paulmurugan R, Berger F, Stiles B, Nagayama Y, Wu H, Gambhir SS. MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene. Gene Therapy. 11: 609-18. PMID 14724687 DOI: 10.1038/Sj.Gt.3302194  0.684
2003 Maliekal TT, Antony ML, Nair A, Paulmurugan R, Karunagaran D. Loss of expression, and mutations of Smad 2 and Smad 4 in human cervical cancer. Oncogene. 22: 4889-97. PMID 12894231 DOI: 10.1038/Sj.Onc.1206806  0.314
2003 Paulmurugan R, Gambhir SS. Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragment-assisted complementation. Analytical Chemistry. 75: 1584-9. PMID 12705589 DOI: 10.1021/Ac020731C  0.45
2002 Paulmurugan R, Umezawa Y, Gambhir SS. Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies Proceedings of the National Academy of Sciences of the United States of America. 99: 15608-15613. PMID 12438689 DOI: 10.1073/Pnas.242594299  0.472
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