| Year |
Citation |
Score |
| 2020 |
Jang J, To C, De Clercq DJH, Park E, Ponthier CM, Shin BH, Mushajiang M, Nowak RP, Fischer ES, Eck MJ, Jänne PA, Gray NS. Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations. Angewandte Chemie (International Ed. in English). PMID 32510788 DOI: 10.1002/Anie.202003500 |
0.572 |
|
| 2019 |
De Clercq DJH, Heppner DE, To C, Jang J, Park E, Yun CH, Mushajiang M, Shin BH, Gero TW, Scott DA, Jänne PA, Eck MJ, Gray NS. Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors. Acs Medicinal Chemistry Letters. 10: 1549-1553. PMID 31749909 DOI: 10.1021/Acsmedchemlett.9B00381 |
0.576 |
|
| 2019 |
Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature. PMID 31581174 DOI: 10.1038/S41586-019-1660-Y |
0.701 |
|
| 2019 |
To C, Jang J, Chen T, Park E, Mushajiang M, De Clercq DJH, Xu M, Wang S, Cameron MD, Heppner DE, Shin BH, Gero TW, Yang A, Dahlberg SE, Wong KK, et al. Single and dual targeting of mutant EGFR with an allosteric inhibitor. Cancer Discovery. PMID 31092401 DOI: 10.1158/2159-8290.Cd-18-0903 |
0.586 |
|
| 2018 |
Jang J, Son J, Park E, Kosaka T, Saxon JA, De Clercq D, Choi HG, Tanizaki J, Eck MJ, Jänne PA, Gray NS. Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor. Angewandte Chemie (International Ed. in English). PMID 29978938 DOI: 10.1002/Anie.201805187 |
0.576 |
|
| 2018 |
Patsoukis N, Duke-Cohan J, Chaudhri A, Park E, Asia C, Berg A, Freeman GJ, Eck M, Boussiotis VA. The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition Blood. 132: 862-862. DOI: 10.1182/Blood-2018-99-117486 |
0.537 |
|
| 2016 |
Ficarro SB, Browne CM, Card JD, Alexander WM, Zhang T, Park E, McNally R, Dhe-Paganon S, Seo HS, Lamberto I, Eck MJ, Buhrlage SJ, Gray NS, Marto JA. Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes. Analytical Chemistry. 88: 12248-12254. PMID 28193034 DOI: 10.1021/Acs.Analchem.6B03394 |
0.516 |
|
| 2016 |
Jia Y, Yun CH, Park E, Ercan D, Manuia M, Juarez J, Xu C, Rhee K, Chen T, Zhang H, Palakurthi S, Jang J, Lelais G, DiDonato M, Bursulaya B, et al. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors. Nature. 534: 129-32. PMID 27251290 DOI: 10.1038/Nature17960 |
0.592 |
|
| 2016 |
Fischer ES, Park E, Eck MJ, Thomä NH. SPLINTS: small-molecule protein ligand interface stabilizers. Current Opinion in Structural Biology. 37: 115-122. PMID 26829757 DOI: 10.1016/J.Sbi.2016.01.004 |
0.555 |
|
| 2015 |
Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AK, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nature Structural & Molecular Biology. 22: 703-11. PMID 26280531 DOI: 10.1038/Nsmb.3074 |
0.581 |
|
| 2015 |
Park EY, Lim MK, Kim BM, Jeong BY, Oh JK, Yun EH. Factors Related to Relapse After 6 Months of Smoking Cessation Among Men in the Republic of Korea: A Cross-Sectional Study. Medicine. 94: e1180. PMID 26200623 DOI: 10.1097/MD.0000000000001180 |
0.402 |
|
| 2015 |
Park E, Graziano BR, Zheng W, Garabedian M, Goode BL, Eck MJ. Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure (London, England : 1993). PMID 26118535 DOI: 10.1016/J.Str.2015.05.015 |
0.562 |
|
| 2015 |
Park EY, Yun EH, Lim MK, Lee DH, Yang W, Jeong BY, Hwang SH. Consequences of Incomplete Smoke-free Legislation in the Republic of Korea: Results from Environmental and Biochemical Monitoring: community based study. Cancer Research and Treatment : Official Journal of Korean Cancer Association. PMID 25943320 DOI: 10.4143/crt.2014.269 |
0.391 |
|
| 2014 |
Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, Cao SA, Park E, Eck MJ, Scully R, Brown M, Marto JA, Livingston DM. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discovery. 4: 1430-47. PMID 25252691 DOI: 10.1158/2159-8290.Cd-13-0891 |
0.543 |
|
| 2014 |
He N, Kim N, Song M, Park C, Kim S, Park EY, Yim HY, Kim K, Park JH, Kim KI, Zhang F, Mills GB, Yoon S. Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D. Molecular Cancer Therapeutics. 13: 2463-73. PMID 25122068 DOI: 10.1158/1535-7163.Mct-14-0297 |
0.321 |
|
| 2014 |
Yasuda H, Park E, Yun CH, Sng NJ, Lucena-Araujo AR, Yeo WL, Huberman MS, Cohen DW, Nakayama S, Ishioka K, Yamaguchi N, Hanna M, Oxnard GR, Lathan CS, Moran T, et al. Structural, biochemical, and clinical characterization of Epidermal Growth Factor Receptor (EGFR) exon 20 insertion mutations in lung cancer (Science Translational Medicine (2014) 6, (225er1)) Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3008733 |
0.554 |
|
| 2013 |
Yasuda H, Park E, Yun CH, Sng NJ, Lucena-Araujo AR, Yeo WL, Huberman MS, Cohen DW, Nakayama S, Ishioka K, Yamaguchi N, Hanna M, Oxnard GR, Lathan CS, Moran T, et al. Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer. Science Translational Medicine. 5: 216ra177. PMID 24353160 DOI: 10.1126/Scitranslmed.3007205 |
0.576 |
|
| 2012 |
Tu D, Graziano BR, Park E, Zheng W, Li Y, Goode BL, Eck MJ. Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6. Proceedings of the National Academy of Sciences of the United States of America. 109: E3424-33. PMID 23161908 DOI: 10.1073/Pnas.1203035109 |
0.575 |
|
| 2010 |
Lee BG, Park EY, Lee KE, Jeon H, Sung KH, Paulsen H, Rübsamen-Schaeff H, Brötz-Oesterhelt H, Song HK. Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism. Nature Structural & Molecular Biology. 17: 471-8. PMID 20305655 DOI: 10.1038/Nsmb.1787 |
0.678 |
|
| 2010 |
Park EY, Kwon OB, Jeong BC, Yi JS, Lee CS, Ko YG, Song HK. Crystal structure of PRY-SPRY domain of human TRIM72. Proteins. 78: 790-5. PMID 19967786 DOI: 10.1002/Prot.22647 |
0.613 |
|
| 2009 |
Park EY, Choi WS, Oh SI, Kim KN, Shin JS, Song HK. Biochemical and structural characterization of 5'-methylthioadenosine nucleosidases from Arabidopsis thaliana. Biochemical and Biophysical Research Communications. 381: 619-24. PMID 19249293 DOI: 10.1016/J.Bbrc.2009.02.106 |
0.465 |
|
| 2009 |
Hong YH, Ahn HC, Lim J, Kim HM, Ji HY, Lee S, Kim JH, Park EY, Song HK, Lee BJ. Identification of a novel ubiquitin binding site of STAM1 VHS domain by NMR spectroscopy. Febs Letters. 583: 287-92. PMID 19111546 DOI: 10.1016/J.Febslet.2008.12.034 |
0.492 |
|
| 2008 |
Park EY, Song HK. A degradation signal recognition in prokaryotes. Journal of Synchrotron Radiation. 15: 246-9. PMID 18421150 DOI: 10.1107/S0909049507062826 |
0.493 |
|
| 2007 |
Park EY, Lee BG, Hong SB, Kim HW, Jeon H, Song HK. Structural basis of SspB-tail recognition by the zinc binding domain of ClpX. Journal of Molecular Biology. 367: 514-26. PMID 17258768 DOI: 10.1016/J.Jmb.2007.01.003 |
0.667 |
|
| 2006 |
Park EY, Oh SI, Nam MJ, Shin JS, Kim KN, Song HK. Crystal structure of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana at 1.5-A resolution. Proteins. 65: 519-23. PMID 16909418 DOI: 10.1002/Prot.21120 |
0.434 |
|
| 2004 |
Park EY, Kim JA, Kim HW, Kim YS, Song HK. Crystal structure of the Bowman-Birk inhibitor from barley seeds in ternary complex with porcine trypsin. Journal of Molecular Biology. 343: 173-86. PMID 15381428 DOI: 10.1016/J.Jmb.2004.08.027 |
0.53 |
|
| 2004 |
Choi JM, Park EY, Kim JH, Chang SK, Cho Y. Probing the functional importance of the hexameric ring structure of RNase PH. The Journal of Biological Chemistry. 279: 755-64. PMID 14573594 DOI: 10.1074/Jbc.M309628200 |
0.425 |
|
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