| Year |
Citation |
Score |
| 2019 |
Menegaz D, Hagan DW, Almaça J, Cianciaruso C, Rodriguez-Diaz R, Molina J, Dolan RM, Becker MW, Schwalie PC, Nano R, Lebreton F, Kang C, Sah R, Gaisano HY, Berggren PO, ... Baekkeskov S, et al. MECHANISM AND EFFECTS OF PULSATILE GABA SECRETION FROM CYTOSOLIC POOLS IN THE HUMAN BETA CELL. Nature Metabolism. 1: 1110-1126. PMID 32432213 DOI: 10.1038/s42255-019-0135-7 |
0.692 |
|
| 2017 |
Baekkeskov S, Hubbell JA, Phelps EA. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Advanced Drug Delivery Reviews. PMID 28625830 DOI: 10.1016/J.Addr.2017.06.007 |
0.737 |
|
| 2017 |
Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Scientific Reports. 7: 46801. PMID 28485397 DOI: 10.1038/srep46801 |
0.711 |
|
| 2017 |
Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Scientific Reports. 7: 45961. PMID 28401888 DOI: 10.1038/Srep45961 |
0.74 |
|
| 2017 |
Cianciaruso C, Phelps E, Baekkeskov S. Preparation of monolayer cultures of primary rat and human islet cells on glass for super-resolution and live cell imaging Protocol Exchange. DOI: 10.1038/Protex.2017.039 |
0.676 |
|
| 2016 |
Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Ahmed MA, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S. Primary Human and Rat Beta Cells Release the Intracellular Autoantigens GAD65, IA-2 and Proinsulin in Exosomes Together with Cytokine-Induced Enhancers of Immunity. Diabetes. PMID 27872147 DOI: 10.2337/Db16-0671 |
0.746 |
|
| 2016 |
Phelps EA, Cianciaruso C, Michael IP, Pasquier M, Kanaani J, Nano R, Lavallard V, Billestrup N, Hubbell JA, Baekkeskov S. Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity. Diabetes. PMID 27284108 DOI: 10.2337/Db16-0180 |
0.754 |
|
| 2015 |
Kanaani J, Cianciaruso C, Phelps EA, Pasquier M, Brioudes E, Billestrup N, Baekkeskov S. Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons. Plos One. 10: e0117130. PMID 25647668 DOI: 10.1371/Journal.Pone.0117130 |
0.701 |
|
| 2010 |
Kanaani J, Kolibachuk J, Martinez H, Baekkeskov S. Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clusters. The Journal of Cell Biology. 190: 911-25. PMID 20805323 DOI: 10.1083/Jcb.200912101 |
0.348 |
|
| 2009 |
Elagin RB, Balijepalli S, Diacovo MJ, Baekkeskov S, Jaume JC. Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice. Journal of Autoimmunity. 33: 50-7. PMID 19289270 DOI: 10.1016/J.Jaut.2009.02.004 |
0.449 |
|
| 2008 |
Kanaani J, Patterson G, Schaufele F, Lippincott-Schwartz J, Baekkeskov S. A palmitoylation cycle dynamically regulates partitioning of the GABA-synthesizing enzyme GAD65 between ER-Golgi and post-Golgi membranes. Journal of Cell Science. 121: 437-49. PMID 18230651 DOI: 10.1242/Jcs.011916 |
0.327 |
|
| 2003 |
Hayakawa N, Premawardhana LD, Powell M, Masuda M, Arnold C, Sanders J, Evans M, Chen S, Jaume JC, Baekkeskov S, Smith BR, Furmaniak J. Isolation and characterization of human monoclonal autoantibodies to glutamic acid decarboxylase. Autoimmunity. 35: 343-55. PMID 12515289 DOI: 10.1080/0891693021000003206 |
0.32 |
|
| 2002 |
Jaume JC, Parry SL, Madec AM, Sønderstrup G, Baekkeskov S. Suppressive effect of glutamic acid decarboxylase 65-specific autoimmune B lymphocytes on processing of T cell determinants located within the antibody epitope. Journal of Immunology (Baltimore, Md. : 1950). 169: 665-72. PMID 12097368 DOI: 10.4049/Jimmunol.169.2.665 |
0.435 |
|
| 2002 |
Wolfe T, Bot A, Hughes A, Möhrle U, Rodrigo E, Jaume JC, Baekkeskov S, von Herrath M. Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety. European Journal of Immunology. 32: 113-21. PMID 11754351 DOI: 10.1002/1521-4141(200201)32:1<113::Aid-Immu113>3.0.Co;2-C |
0.383 |
|
| 2000 |
Shi Y, Kanaani J, Menard-Rose V, Ma YH, Chang PY, Hanahan D, Tobin A, Grodsky G, Baekkeskov S. Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 279: E684-94. PMID 10950838 DOI: 10.1152/Ajpendo.2000.279.3.E684 |
0.434 |
|
| 2000 |
Roll U, Turck CW, Gitelman SE, Rosenthal SM, Nolte MS, Masharani U, Ziegler AG, Baekkeskov S. Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients. Diabetologia. 43: 598-608. PMID 10855535 DOI: 10.1007/S001250051349 |
0.347 |
|
| 2000 |
O'Rourke RW, Kang SM, Lower JA, Feng S, Ascher NL, Baekkeskov S, Stock PG. A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival. Transplantation. 69: 1440-6. PMID 10798768 DOI: 10.1097/00007890-200004150-00039 |
0.413 |
|
| 2000 |
Kanaani J, Lissin D, Kash SF, Baekkeskov S. The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65. The Journal of Biological Chemistry. 274: 37200-9. PMID 10601283 DOI: 10.1074/Jbc.274.52.37200 |
0.317 |
|
| 1999 |
Tian N, Petersen C, Kash S, Baekkeskov S, Copenhagen D, Nicoll R. The role of the synthetic enzyme GAD65 in the control of neuronal γ- aminobutyric acid release Proceedings of the National Academy of Sciences of the United States of America. 96: 12911-12916. PMID 10536022 DOI: 10.1073/Pnas.96.22.12911 |
0.333 |
|
| 1999 |
Kash SF, Condie BG, Baekkeskov S. Glutamate decarboxylase and GABA in pancreatic islets: lessons from knock-out mice. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 31: 340-4. PMID 10422732 DOI: 10.1055/S-2007-978750 |
0.386 |
|
| 1999 |
Schwartz HL, Chandonia JM, Kash SF, Kanaani J, Tunnell E, Domingo A, Cohen FE, Banga JP, Madec AM, Richter W, Baekkeskov S. High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase. Journal of Molecular Biology. 287: 983-99. PMID 10222205 DOI: 10.1006/Jmbi.1999.2655 |
0.358 |
|
| 1999 |
Kash SF, Tecott LH, Hodge C, Baekkeskov S. Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 96: 1698-703. PMID 9990087 DOI: 10.1073/Pnas.96.4.1698 |
0.308 |
|
| 1998 |
Bridgett M, Cetkovic-Cvrlje M, O'Rourke R, Shi Y, Narayanswami S, Lambert J, Ramiya V, Baekkeskov S, Leiter EH. Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells Diabetes. 47: 1848-1856. DOI: 10.2337/Diabetes.47.12.1848 |
0.35 |
|
| 1998 |
O'Rourke R, Kang S, Lower J, Feng S, Ascher N, Baekkeskov S, Stock P. A DENDRITIC CELL LINE EXPRESSING CTLA4-IG AS A MEANS TO INACTIVATE THE ALLOREACTIVE T CELL REPERTOIRE Transplantation. 66: S12. DOI: 10.1097/00007890-199810270-00075 |
0.374 |
|
| 1997 |
Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14060-5. PMID 9391152 DOI: 10.1073/Pnas.94.25.14060 |
0.303 |
|
| 1997 |
Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, Baekkeskov S. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction Nature Medicine. 3: 738-743. PMID 9212099 DOI: 10.1038/Nm0797-738 |
0.393 |
|
| 1997 |
Namchuk M, Lindsay L, Turck CW, Kanaani J, Baekkeskov S. Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65α Journal of Biological Chemistry. 272: 1548-1557. PMID 8999827 DOI: 10.1074/Jbc.272.3.1548 |
0.384 |
|
| 1996 |
Aanstoot HJ, Kang SM, Kim J, Lindsay LA, Roll U, Knip M, Atkinson M, Mose-Larsen P, Fey S, Ludvigsson J, Landin L, Bruining J, Maclaren N, Akerblom HK, Baekkeskov S. Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes. Journal of Clinical Investigation. 97: 2772-2783. PMID 8675688 DOI: 10.1172/Jci118732 |
0.517 |
|
| 1994 |
Shi Y, Veit B, Baekkeskov S. Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65. The Journal of Cell Biology. 124: 927-34. PMID 8132714 DOI: 10.1083/Jcb.124.6.927 |
0.373 |
|
| 1994 |
Aanstoot H, Sigurdsson E, Jaffe M, Shi Y, Christgau S, Grobbee D, Bruining GJ, Molenaar J, Hofman A, Baekkeskov S. Value of Antibodies to GAD65 Combined With Islet Cell Cytoplasmic Antibodies for Predicting IDDM in a Childhood Population Diabetologia. 37: 917-924. PMID 7806022 DOI: 10.1007/Bf00400948 |
0.369 |
|
| 1994 |
Kim J, Namchuk M, Bugawan T, Fu Q, Jaffe M, Shi Y, Aanstoot HJ, Turck CW, Erlich H, Lennon V, Baekkeskov S. Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus Journal of Experimental Medicine. 180: 595-606. PMID 7519242 DOI: 10.1084/Jem.180.2.595 |
0.45 |
|
| 1993 |
Radvanyi F, Christgau S, Baekkeskov S, Jolicoeur C, Hanahan D. Pancreatic β cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: A potentially general technique for isolating physiologically representative cell lines Molecular and Cellular Biology. 13: 4223-4232. PMID 8391634 DOI: 10.1128/Mcb.13.7.4223 |
0.509 |
|
| 1993 |
Kim J, Richter W, Aanstoot HJ, Shi Y, Fu Q, Rajotte R, Warnock G, Baekkeskov S. Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets. Diabetes. 42: 1799-808. PMID 8243826 DOI: 10.2337/Diab.42.12.1799 |
0.441 |
|
| 1993 |
Baekkeskov S, Aanstoot HJ, Fu Q, Jaffe M, Kim J, Quan J, Richter W, Shi Y. The glutamate decarboxylase and 38KD autoantigens in type 1 diabetes: aspects of structure and epitope recognition. Autoimmunity. 24-6. PMID 7692998 DOI: 10.3109/08916939309008857 |
0.501 |
|
| 1993 |
Richter W, Shi Y, Baekkeskov S. Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 90: 2832-6. PMID 7681990 DOI: 10.1073/Pnas.90.7.2832 |
0.404 |
|
| 1992 |
Møller CJ, Christgau S, Williamson MR, Madsen OD, Niu ZP, Bock E, Baekkeskov S. Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas. Molecular Endocrinology (Baltimore, Md.). 6: 1332-42. PMID 1406710 DOI: 10.1210/Mend.6.8.1406710 |
0.444 |
|
| 1992 |
Christgau S, Aanstoot HJ, Schierbeck H, Begley K, Tullin S, Hejnaes K, Baekkeskov S. Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. The Journal of Cell Biology. 118: 309-20. PMID 1321158 DOI: 10.1083/Jcb.118.2.309 |
0.487 |
|
| 1991 |
Sigurdsson E, Baekkeskov S. The 64-kDa beta cell membrane autoantigen and other target molecules of humoral autoimmunity in insulin-dependent diabetes mellitus. Current Topics in Microbiology and Immunology. 164: 143-68. PMID 2073783 DOI: 10.1007/978-3-642-75741-9_8 |
0.389 |
|
| 1991 |
Christgau S, Schierbeck H, Aanstoot H, Aagaard L, Begley K, Kofod H, Hejnaes K, Baekkeskov S. Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble. Journal of Biological Chemistry. 266: 21257-21264. DOI: 10.1016/s0021-9258(18)54849-3 |
0.326 |
|
| 1991 |
Christgau S, Schierbeck H, Aanstoot H, Aagaard L, Begley K, Kofod H, Hejnaes K, Baekkeskov S. Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble. Journal of Biological Chemistry. 266: 23516. DOI: 10.1016/s0021-9258(18)54529-4 |
0.326 |
|
| 1990 |
Baekkeskov S, Aanstoot HJ, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, De Camilli P, Camilli PD. Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature. 347: 151-6. PMID 1697648 DOI: 10.1038/347151A0 |
0.416 |
|
| 1990 |
Baekkeskov S, Aanstoot H, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Oleson H, Camilli PD. Erratum: Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase Nature. 347: 782-782. DOI: 10.1038/347782A0 |
0.368 |
|
| 1990 |
Baekkeskov S. Characterization of the 64k autoantigen in type 1 diabetes Journal of Autoimmunity. 3: 45-46. DOI: 10.1016/0896-8411(90)90011-G |
0.313 |
|
| 1989 |
Schoenle EJ, Boltshauser EJ, Baekkeskov S, Landin Olsson M, Torresani T, von Felten A. Preclinical and manifest diabetes mellitus in young patients with Friedreich's ataxia: no evidence of immune process behind the islet cell destruction. Diabetologia. 32: 378-81. PMID 2668085 DOI: 10.1007/Bf00277262 |
0.389 |
|
| 1988 |
Christie M, Landin-Olsson M, Sundkvist G, Dahlquist G, Lernmark A, Baekkeskov S. Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes Diabetologia. 31: 597-602. PMID 3065114 DOI: 10.1007/Bf00264766 |
0.401 |
|
| 1988 |
Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D, Baekkeskov S. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proceedings of the National Academy of Sciences of the United States of America. 85: 9037-41. PMID 2848253 DOI: 10.1073/Pnas.85.23.9037 |
0.481 |
|
| 1988 |
Warnock GL, Ellis D, Rajotte RV, Dawidson I, Baekkeskov S, Egebjerg J. Studies of the isolation and viability of human islets of Langerhans. Transplantation. 45: 957-63. PMID 2835843 DOI: 10.1097/00007890-198805000-00024 |
0.333 |
|
| 1987 |
Baekkeskov S, Landin M, Kristensen JK, Srikanta S, Bruining GJ, Mandrup-Poulsen T, de Beaufort C, Soeldner JS, Eisenbarth G, Lindgren F. Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes. The Journal of Clinical Investigation. 79: 926-34. PMID 3546382 DOI: 10.1172/Jci112903 |
0.461 |
|
| 1987 |
Efrat S, Baekkeskov S, Lane D, Hanahan D. Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes. The Embo Journal. 6: 2699-2704. DOI: 10.1002/J.1460-2075.1987.Tb02562.X |
0.421 |
|
| 1985 |
Lernmark A, Baekkeskov S, Gerling I, Kastern W, Knutson C, Michelsen B. Immunological aspects of type 1 and 2 diabetes mellitus. Advances in Experimental Medicine and Biology. 189: 107-27. PMID 4036712 DOI: 10.1007/978-1-4757-1850-8_7 |
0.406 |
|
| 1984 |
Baekkeskov S, Dyrberg T, Lernmark A. Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science (New York, N.Y.). 224: 1348-50. PMID 6374896 DOI: 10.1126/Science.6374896 |
0.453 |
|
| 1983 |
Dyrberg T, Nakhooda AF, Baekkeskov S, Lernmark A, Poussier P, Marliss EB. Islet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat. Diabetes. 31: 278-81. PMID 6759244 DOI: 10.2337/Diab.31.3.278 |
0.401 |
|
| 1983 |
Kanatsuna T, Baekkeskov S, Lernmark A, Ludvigsson J. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release. Diabetes. 32: 520-4. PMID 6354781 DOI: 10.2337/Diab.32.6.520 |
0.393 |
|
| 1982 |
Dyrberg T, Baekkeskov S, Lernmark A. Specific pancreatic beta-cell surface antigens recognized by a xenogenic antiserum. The Journal of Cell Biology. 94: 472-7. PMID 7050130 DOI: 10.1083/Jcb.94.2.472 |
0.489 |
|
| 1982 |
Baekkeskov S, Nielsen JH, Marner B, Bilde T, Ludvigsson J, Lernmark A. Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature. 298: 167-9. PMID 7045690 DOI: 10.1038/298167A0 |
0.455 |
|
| 1982 |
Lernmark A, Baekkeskov S. Islet cell antibodies-theoretical and practical implications. Diabetologia. 21: 431-5. PMID 7028555 DOI: 10.1007/Bf00257781 |
0.369 |
|
| 1982 |
Baekkeskov S, Kanatsuna T, Nielsen JH, Marner B, Lernmark Å. SPECIFIC HUMAN PANCREATIC ISLET CELL PROTEINS RECOGNIZED BY ANTIBODIES IN DIABETIC CHILDREN Annals of the New York Academy of Sciences. 392: 378-378. DOI: 10.1111/J.1749-6632.1982.Tb36124.X |
0.476 |
|
| 1981 |
Baekkeskov S, Kanatsuna T, Klareskog L, Nielsen DA, Peterson PA, Rubenstein AH, Steiner DF, Lernmark A. Expression of major histocompatibility antigens on pancreatic islet cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 6456-60. PMID 7031653 DOI: 10.1073/Pnas.78.10.6456 |
0.515 |
|
| 1980 |
Rovis L, Baekkeskov S. Sub-cellular fractionation of Trypanosoma brucei. Isolation and characterization of plasma membranes. Parasitology. 80: 507-24. PMID 6248830 DOI: 10.1017/S0031182000000974 |
0.303 |
|
| Show low-probability matches. |