| Year |
Citation |
Score |
| 2022 |
Puris E, Saveleva L, de Sousa Maciel I, Kanninen KM, Auriola S, Fricker G. Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer's Disease. Molecular Neurobiology. PMID 36367657 DOI: 10.1007/s12035-022-03111-y |
0.305 |
|
| 2022 |
Puris E, Fricker G, Gynther M. Targeting Transporters for Drug Delivery to the Brain: Can We Do Better? Pharmaceutical Research. PMID 35359241 DOI: 10.1007/s11095-022-03241-x |
0.36 |
|
| 2022 |
Balzer V, Poc P, Puris E, Martin S, Aliasgari M, Auriola S, Fricker G. Re-evaluation of the hCMEC/D3 based in vitro BBB model for ABC transporter studies. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 173: 12-21. PMID 35227855 DOI: 10.1016/j.ejpb.2022.02.017 |
0.352 |
|
| 2020 |
Helms HCC, Kristensen M, Saaby L, Fricker G, Brodin B. Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB). Handbook of Experimental Pharmacology. PMID 33367937 DOI: 10.1007/164_2020_403 |
0.358 |
|
| 2020 |
Bauer B, Renfro JL, Karnaky KJ, Masereeuw R, Fricker G, Cannon RE, Hartz AMS. David S. Miller: Scientist, Mentor, Friend-a tribute and thank you. Fluids and Barriers of the Cns. 17: 56. PMID 32928243 DOI: 10.1186/S12987-020-00220-5 |
0.319 |
|
| 2020 |
Binnefeld M, Fritz S, Balzer V, Skalická V, Witzigmann D, Kauczor HU, Fricker G, Salomon JJ. Physicochemical and biopharmaceutical characterization of novel Matrix-Liposomes. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 32522680 DOI: 10.1016/J.Ejpb.2020.06.001 |
0.378 |
|
| 2020 |
Köthe T, Martin S, Reich G, Fricker G. Dual Asymmetric Centrifugation as a Novel Method to Prepare Highly Concentrated Dispersions of PEG-b-PCL Polymersomes as Drug Carriers. International Journal of Pharmaceutics. 119087. PMID 32213299 DOI: 10.1016/J.Ijpharm.2020.119087 |
0.315 |
|
| 2019 |
Zaremba A, Helm F, Fricker G. Impact of Zn on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo. Molecular Pharmaceutics. 16: 305-317. PMID 30422662 DOI: 10.1021/Acs.Molpharmaceut.8B00987 |
0.459 |
|
| 2019 |
Schmitt MV, Lienau P, Fricker G, Reichel A. Quantitation of Lysosomal Trapping of Basic Lipophilic Compounds Using In Vitro Assays and In Silico Predictions Based on the Determination of the Full pH Profile of the Endo-/Lysosomal System in Rat Hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 47: 49-57. PMID 30409837 DOI: 10.1124/Dmd.118.084541 |
0.357 |
|
| 2018 |
Mahringer A, Bernd A, Miller DS, Fricker G. Arylhydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules. Biological Chemistry. PMID 30913027 DOI: 10.1515/Hsz-2018-0425 |
0.503 |
|
| 2018 |
Disch L, Forsch K, Siewert B, Drewe J, Fricker G. In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts. Planta Medica. 84: 795-805. PMID 29341029 DOI: 10.1055/S-0044-100401 |
0.312 |
|
| 2017 |
Bernard-Gauthier V, Mossine AV, Mahringer A, Aliaga A, Bailey JJ, Shao X, Stauff J, Arteaga J, Sherman PS, Grand'Maison M, Rochon PL, Wängler B, Wängler C, Bartenstein P, Kostikov A, ... ... Fricker G, et al. Identification of 18FTRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging. Journal of Medicinal Chemistry. PMID 29257860 DOI: 10.1021/Acs.Jmedchem.7B01607 |
0.338 |
|
| 2017 |
Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbrouke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M. Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. Fluids and Barriers of the Cns. 14: 31. PMID 29110676 DOI: 10.1186/S12987-017-0079-9 |
0.311 |
|
| 2017 |
Zaremba A, Miller DS, Fricker G. Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus). Toxicology and Applied Pharmacology. PMID 28882485 DOI: 10.1016/J.Taap.2017.09.001 |
0.506 |
|
| 2017 |
Uhl P, Pantze S, Storck P, Parmentier J, Witzigmann D, Hofhaus G, Huwyler J, Mier W, Fricker G. Oral delivery of vancomycin by tetraether lipid liposomes. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 108: 111-118. PMID 28716758 DOI: 10.1016/J.Ejps.2017.07.013 |
0.363 |
|
| 2017 |
Bernard-Gauthier V, Bailey JJ, Mossine AV, Lindner SK, Vomacka L, Aliaga A, Shao X, Quesada CA, Sherman PS, Mahringer A, Kostikov A, Grand'Maison M, Rosa-Neto P, Soucy JP, Thiel A, ... ... Fricker G, et al. A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation and First-in-Human. Journal of Medicinal Chemistry. PMID 28696690 DOI: 10.1021/Acs.Jmedchem.7B00396 |
0.314 |
|
| 2017 |
Ćurić A, Möschwitzer JP, Fricker G. Development and characterization of novel highly-loaded itraconazole poly(butyl cyanoacrylate) polymeric nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 114: 175-185. PMID 28159723 DOI: 10.1016/J.Ejpb.2017.01.014 |
0.351 |
|
| 2017 |
Jacobsen AC, Jensen SM, Fricker G, Brandl M, Treusch A. Archaeal lipids in oral delivery of therapeutic peptides. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28108360 DOI: 10.1016/J.Ejps.2016.12.036 |
0.315 |
|
| 2017 |
Weinheimer M, Fricker G, Burhenne J, Mylius P, Schubert R. The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 108: 13-22. PMID 27590127 DOI: 10.1016/J.Ejps.2016.08.055 |
0.383 |
|
| 2017 |
Forsch K, Siewert B, Drewe J, Fricker G, Disch L. Sustained Release for St. John?s Wort: A Rational Idea? Journal of Bioequivalence & Bioavailability. 9. DOI: 10.4172/Jbb.1000363 |
0.304 |
|
| 2016 |
Tremmel R, Uhl P, Helm F, Wupperfeld D, Sauter M, Mier W, Stremmel W, Hofhaus G, Fricker G. Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes. International Journal of Pharmaceutics. 512: 87-95. PMID 27553779 DOI: 10.1016/J.Ijpharm.2016.08.040 |
0.385 |
|
| 2016 |
Mahringer A, Fricker G. ABC transporters at the blood-brain barrier. Expert Opinion On Drug Metabolism & Toxicology. 12: 499-508. PMID 26998936 DOI: 10.1517/17425255.2016.1168804 |
0.436 |
|
| 2016 |
Uhl P, Helm F, Hofhaus G, Brings S, Kaufman C, Leotta K, Urban S, Haberkorn U, Mier W, Fricker G. A liposomal formulation for the oral application of the investigational hepatitis B drug Myrcludex B European Journal of Pharmaceutics and Biopharmaceutics. 103: 159-166. DOI: 10.1016/J.Ejpb.2016.03.031 |
0.315 |
|
| 2015 |
Ćurić A, Keller BL, Reul R, Möschwitzer J, Fricker G. Development and lyophilization of itraconazole loaded poly(butylcyanoacrylate) nanospheres as a drug delivery system. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 78: 121-31. PMID 26171880 DOI: 10.1016/J.Ejps.2015.07.010 |
0.334 |
|
| 2015 |
Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharmaceutical Research. 32: 2973-82. PMID 25986174 DOI: 10.1007/S11095-015-1679-1 |
0.364 |
|
| 2015 |
Helm F, Fricker G. Liposomal conjugates for drug delivery to the central nervous system. Pharmaceutics. 7: 27-42. PMID 25835091 DOI: 10.3390/Pharmaceutics7020027 |
0.466 |
|
| 2015 |
Kolter M, Ott M, Hauer C, Reimold I, Fricker G. Nanotoxicity of poly(n-butylcyano-acrylate) nanoparticles at the blood-brain barrier, in human whole blood and in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 197: 165-79. PMID 25445700 DOI: 10.1016/J.Jconrel.2014.11.005 |
0.37 |
|
| 2015 |
Uhl P, Fricker G, Haberkorn U, Mier W. Radionuclides in drug development. Drug Discovery Today. 20: 198-208. PMID 25304182 DOI: 10.1016/J.Drudis.2014.09.027 |
0.314 |
|
| 2015 |
Kiessling H, Schulz I, Haltner E, Fricker G, Stelzle M, Schütte J. Mikrofluidisches 3D-Zellkulturmodell der Blut-Hirn-Schranke Biospektrum. 21: 175-178. DOI: 10.1007/S12268-015-0558-Y |
0.341 |
|
| 2014 |
Parmentier J, Hofhaus G, Thomas S, Cuesta LC, Gropp F, Schröder R, Hartmann K, Fricker G. Improved oral bioavailability of human growth hormone by a combination of liposomes containing bio-enhancers and tetraether lipids and omeprazole. Journal of Pharmaceutical Sciences. 103: 3985-3993. PMID 25332052 DOI: 10.1002/Jps.24215 |
0.326 |
|
| 2014 |
Heshmati N, Cheng X, Dapat E, Sassene P, Eisenbrand G, Fricker G, Müllertz A. In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems. The Journal of Pharmacy and Pharmacology. 66: 1567-75. PMID 24961657 DOI: 10.1111/Jphp.12286 |
0.3 |
|
| 2014 |
Jähne EA, Eigenmann DE, Culot M, Cecchelli R, Walter FR, Deli MA, Tremmel R, Fricker G, Smiesko M, Hamburger M, Oufir M. Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models. Journal of Pharmaceutical and Biomedical Analysis. 98: 235-46. PMID 24949819 DOI: 10.1016/J.Jpba.2014.05.026 |
0.371 |
|
| 2014 |
Noysang C, Mahringer A, Zeino M, Saeed M, Luanratana O, Fricker G, Bauer R, Efferth T. Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand. Journal of Ethnopharmacology. 155: 633-41. PMID 24929106 DOI: 10.1016/J.Jep.2014.06.001 |
0.362 |
|
| 2014 |
Wängler C, Chowdhury S, Höfner G, Djurova P, Purisima EO, Bartenstein P, Wängler B, Fricker G, Wanner KT, Schirrmacher R. Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding? Journal of Medicinal Chemistry. 57: 4368-81. PMID 24779610 DOI: 10.1021/Jm5004123 |
0.343 |
|
| 2014 |
Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M. What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion? Journal of Pharmaceutical Sciences. 103: 1779-86. PMID 24764046 DOI: 10.1002/Jps.23979 |
0.314 |
|
| 2014 |
Gartzke D, Fricker G. Establishment of optimized MDCK cell lines for reliable efflux transport studies. Journal of Pharmaceutical Sciences. 103: 1298-304. PMID 24532159 DOI: 10.1002/Jps.23901 |
0.346 |
|
| 2014 |
Tajima Y, Nakagawa H, Tamura A, Kadioglu O, Satake K, Mitani Y, Murase H, Regasini LO, Bolzani Vda S, Ishikawa T, Fricker G, Efferth T. Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 21: 323-32. PMID 24135452 DOI: 10.1016/J.Phymed.2013.08.024 |
0.358 |
|
| 2014 |
Pantze SF, Parmentier J, Hofhaus G, Fricker G. Matrix liposomes: A solid liposomal formulation for oral administration European Journal of Lipid Science and Technology. 116: 1145-1154. DOI: 10.1002/Ejlt.201300409 |
0.31 |
|
| 2013 |
Heshmati N, Wagner B, Cheng X, Scholz T, Kansy M, Eisenbrand G, Fricker G. Physicochemical characterization and in vitro permeation of an indirubin derivative. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 50: 467-75. PMID 23994641 DOI: 10.1016/J.Ejps.2013.08.021 |
0.367 |
|
| 2013 |
Heshmati N, Cheng X, Eisenbrand G, Fricker G. Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats. Journal of Pharmaceutical Sciences. 102: 3792-9. PMID 23934779 DOI: 10.1002/Jps.23696 |
0.314 |
|
| 2013 |
Avemary J, Salvamoser JD, Peraud A, Rémi J, Noachtar S, Fricker G, Potschka H. Dynamic regulation of P-glycoprotein in human brain capillaries. Molecular Pharmaceutics. 10: 3333-41. PMID 23924183 DOI: 10.1021/Mp4001102 |
0.436 |
|
| 2013 |
Lenhard T, Hülsermann U, Martinez-Torres F, Fricker G, Meyding-Lamadé U. A simple method to quickly and simultaneously purify and enrich intact rat brain microcapillaries and endothelial and glial cells for ex vivo studies and cell culture. Brain Research. 1519: 9-18. PMID 23665392 DOI: 10.1016/J.Brainres.2013.05.004 |
0.428 |
|
| 2013 |
Buckley ST, Frank KJ, Fricker G, Brandl M. Biopharmaceutical classification of poorly soluble drugs with respect to "enabling formulations". European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 50: 8-16. PMID 23583787 DOI: 10.1016/J.Ejps.2013.04.002 |
0.349 |
|
| 2013 |
Mahringer A, Ardjomand-Woelkart K, Bauer R, Fricker G, Efferth T. Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels. Planta Medica. 79: 214-8. PMID 23322561 DOI: 10.1055/S-0032-1328090 |
0.435 |
|
| 2013 |
Gerbeth K, Hüsch J, Fricker G, Werz O, Schubert-Zsilavecz M, Abdel-Tawab M. In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins. Fitoterapia. 84: 99-106. PMID 23103296 DOI: 10.1016/J.Fitote.2012.10.009 |
0.32 |
|
| 2012 |
Fischer SM, Parmentier J, Buckley ST, Reimold I, Brandl M, Fricker G. Oral bioavailability of ketoprofen in suspension and solution formulations in rats: The influence of poloxamer 188 Journal of Pharmacy and Pharmacology. 64: 1631-1637. PMID 23058050 DOI: 10.1111/J.2042-7158.2012.01541.X |
0.348 |
|
| 2012 |
Martins S, Tho I, Reimold I, Fricker G, Souto E, Ferreira D, Brandl M. Brain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studies. International Journal of Pharmaceutics. 439: 49-62. PMID 23046667 DOI: 10.1016/J.Ijpharm.2012.09.054 |
0.414 |
|
| 2012 |
Hüsch J, Gerbeth K, Fricker G, Setzer C, Zirkel J, Rebmann H, Schubert-Zsilavecz M, Abdel-Tawab M. Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. Journal of Natural Products. 75: 1675-82. PMID 23013292 DOI: 10.1021/Np300009W |
0.332 |
|
| 2012 |
Huber O, Brunner A, Maier P, Kaufmann R, Couraud PO, Cremer C, Fricker G. Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model. Plos One. 7: e44776. PMID 22984556 DOI: 10.1371/Journal.Pone.0044776 |
0.372 |
|
| 2012 |
Frank KJ, Rosenblatt KM, Westedt U, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M. Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs. apparent solubility enhancement. International Journal of Pharmaceutics. 437: 288-93. PMID 22951865 DOI: 10.1016/J.Ijpharm.2012.08.014 |
0.323 |
|
| 2012 |
Parmentier J, Thomas N, Müllertz A, Fricker G, Rades T. Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. International Journal of Pharmaceutics. 437: 253-63. PMID 22939968 DOI: 10.1016/J.Ijpharm.2012.08.018 |
0.33 |
|
| 2012 |
Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Brandl M, Fricker G. Impact of FaSSIF on the solubility and dissolution-/permeation rate of a poorly water-soluble compound. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 47: 16-20. PMID 22579958 DOI: 10.1016/J.Ejps.2012.04.015 |
0.38 |
|
| 2012 |
Buckley ST, Fischer SM, Fricker G, Brandl M. In vitro models to evaluate the permeability of poorly soluble drug entities: Challenges and perspectives European Journal of Pharmaceutical Sciences. 45: 235-250. PMID 22178532 DOI: 10.1016/J.Ejps.2011.12.007 |
0.346 |
|
| 2012 |
Fischer SM, Buckley ST, Kirchmeyer W, Fricker G, Brandl M. Application of simulated intestinal fluid on the phospholipid vesicle-based drug permeation assay International Journal of Pharmaceutics. 422: 52-58. PMID 22027395 DOI: 10.1016/J.Ijpharm.2011.10.026 |
0.371 |
|
| 2012 |
Steglich B, Mahringer A, Li Y, Posner GH, Fricker G, Efferth T. Inhibition of P-glycoprotein by two artemisinin derivatives Natural Products and Bioprospecting. 2: 59-64. DOI: 10.1007/S13659-012-0006-3 |
0.439 |
|
| 2011 |
Mahringer A, Ott M, Reimold I, Reichel V, Fricker G. The ABC of the blood-brain barrier - regulation of drug efflux pumps. Current Pharmaceutical Design. 17: 2762-70. PMID 21827407 DOI: 10.2174/138161211797440221 |
0.464 |
|
| 2011 |
Fischer SM, Flaten GE, Hagesæther E, Fricker G, Brandl M. In-vitro permeability of poorly water soluble drugs in the phospholipid vesicle-based permeation assay: The influence of nonionic surfactants Journal of Pharmacy and Pharmacology. 63: 1022-1030. PMID 21718285 DOI: 10.1111/J.2042-7158.2011.01301.X |
0.374 |
|
| 2011 |
Parmentier J, Thewes B, Gropp F, Fricker G. Oral peptide delivery by tetraether lipid liposomes. International Journal of Pharmaceutics. 415: 150-7. PMID 21664955 DOI: 10.1016/J.Ijpharm.2011.05.066 |
0.326 |
|
| 2011 |
Fischer SM, Brandl M, Fricker G. Effect of the non-ionic surfactant Poloxamer 188 on passive permeability of poorly soluble drugs across Caco-2 cell monolayers European Journal of Pharmaceutics and Biopharmaceutics. 79: 416-422. PMID 21549839 DOI: 10.1016/J.Ejpb.2011.04.010 |
0.402 |
|
| 2011 |
Neuwelt EA, Bauer B, Fahlke C, Fricker G, Iadecola C, Janigro D, Leybaert L, Molnár Z, O'Donnell ME, Povlishock JT, Saunders NR, Sharp F, Stanimirovic D, Watts RJ, Drewes LR. Engaging neuroscience to advance translational research in brain barrier biology. Nature Reviews. Neuroscience. 12: 169-82. PMID 21331083 DOI: 10.1038/Nrn2995 |
0.374 |
|
| 2011 |
Parmentier J, Becker MM, Heintz U, Fricker G. Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastro-intestinal fluids. International Journal of Pharmaceutics. 405: 210-7. PMID 21145956 DOI: 10.1016/J.Ijpharm.2010.12.005 |
0.309 |
|
| 2011 |
Soomro S, Langenberg T, Mahringer A, Konkimalla VB, Horwedel C, Holenya P, Brand A, Cetin C, Fricker G, Dewerchin M, Carmeliet P, Conway EM, Jansen H, Efferth T. Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties. Journal of Cellular and Molecular Medicine. 15: 1122-35. PMID 20629994 DOI: 10.1111/J.1582-4934.2010.01120.X |
0.306 |
|
| 2010 |
Kanzer J, Tho I, Flaten GE, Hölig P, Fricker G, Brandl M. In-vitro permeability screening of melt extrudate formulations containing poorly water-soluble drug compounds using the phospholipid vesicle-based barrier Journal of Pharmacy and Pharmacology. 62: 1591-1598. PMID 21039543 DOI: 10.1111/J.2042-7158.2010.01172.X |
0.375 |
|
| 2010 |
Parmentier J, Hartmann FJ, Fricker G. In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 76: 394-403. PMID 20849953 DOI: 10.1016/J.Ejpb.2010.09.002 |
0.302 |
|
| 2010 |
Mahringer A, Fricker G. BCRP at the blood-brain barrier: genomic regulation by 17β-estradiol. Molecular Pharmaceutics. 7: 1835-47. PMID 20735085 DOI: 10.1021/Mp1001729 |
0.423 |
|
| 2010 |
Kläs J, Wolburg H, Terasaki T, Fricker G, Reichel V. Characterization of immortalized choroid plexus epithelial cell lines for studies of transport processes across the blood-cerebrospinal fluid barrier. Cerebrospinal Fluid Research. 7: 11. PMID 20704740 DOI: 10.1186/1743-8454-7-11 |
0.36 |
|
| 2010 |
Mahringer A, Karamustafa S, Klotz D, Kahl S, Konkimalla VB, Wang Y, Wang J, Liu HY, Boechzelt H, Hao X, Bauer R, Fricker G, Efferth T. Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine. Cancer Genomics & Proteomics. 7: 191-205. PMID 20656985 |
0.343 |
|
| 2010 |
Reichel V, Kläs J, Fricker G, Masereeuw R. Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus. Journal of Neurochemistry. 115: 200-8. PMID 20649844 DOI: 10.1111/J.1471-4159.2010.06915.X |
0.424 |
|
| 2010 |
Fricker G, Kromp T, Wendel A, Blume A, Zirkel J, Rebmann H, Setzer C, Quinkert RO, Martin F, Müller-Goymann C. Phospholipids and lipid-based formulations in oral drug delivery. Pharmaceutical Research. 27: 1469-86. PMID 20411409 DOI: 10.1007/S11095-010-0130-X |
0.354 |
|
| 2010 |
Lechner C, Reichel V, Moenning U, Reichel A, Fricker G. Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 75: 284-90. PMID 20307659 DOI: 10.1016/J.Ejpb.2010.03.008 |
0.351 |
|
| 2010 |
Sauer SW, Opp S, Mahringer A, Kamiński MM, Thiel C, Okun JG, Fricker G, Morath MA, Kölker S. Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus. Biochimica Et Biophysica Acta. 1802: 552-60. PMID 20302929 DOI: 10.1016/J.Bbadis.2010.03.003 |
0.386 |
|
| 2010 |
Ott M, Huls M, Cornelius MG, Fricker G. St. John's Wort constituents modulate P-glycoprotein transport activity at the blood-brain barrier. Pharmaceutical Research. 27: 811-22. PMID 20229133 DOI: 10.1007/S11095-010-0074-1 |
0.425 |
|
| 2009 |
Hülsermann U, Hoffmann MM, Massing U, Fricker G. Uptake of apolipoprotein E fragment coupled liposomes by cultured brain microvessel endothelial cells and intact brain capillaries. Journal of Drug Targeting. 17: 610-8. PMID 19694613 DOI: 10.1080/10611860903105986 |
0.427 |
|
| 2009 |
Mahringer A, Delzer J, Fricker G. A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2). European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 72: 605-13. PMID 19572416 DOI: 10.1016/J.Ejpb.2009.01.010 |
0.322 |
|
| 2009 |
Pinto A, Hoffmans U, Ott M, Fricker G, Metzler-Nolte N. Modification with organometallic compounds improves crossing of the blood-brain barrier of [Leu5]-enkephalin derivatives in an in vitro model system Chembiochem. 10: 1852-1860. PMID 19569087 DOI: 10.1002/Cbic.200900157 |
0.345 |
|
| 2009 |
Kühnle M, Egger M, Müller C, Mahringer A, Bernhardt G, Fricker G, König B, Buschauer A. Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry. 52: 1190-7. PMID 19170519 DOI: 10.1021/Jm8013822 |
0.364 |
|
| 2009 |
Ott M, Fricker G, Bauer B. Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR. The Journal of Pharmacology and Experimental Therapeutics. 329: 141-9. PMID 19147857 DOI: 10.1124/Jpet.108.149690 |
0.484 |
|
| 2009 |
Krüger P, Kanzer J, Hummel J, Fricker G, Schubert-Zsilavecz M, Abdel-Tawab M. Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 36: 275-84. PMID 19010411 DOI: 10.1016/J.Ejps.2008.10.005 |
0.401 |
|
| 2008 |
Fricker G. Drug interactions with natural products at the blood brain barrier. Current Drug Metabolism. 9: 1019-26. PMID 19075618 DOI: 10.2174/138920008786927758 |
0.419 |
|
| 2008 |
Reichel V, Miller DS, Fricker G. Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1311-9. PMID 18650317 DOI: 10.1152/Ajpregu.90373.2008 |
0.499 |
|
| 2008 |
Reimold I, Domke D, Bender J, Seyfried CA, Radunz HE, Fricker G. Delivery of nanoparticles to the brain detected by fluorescence microscopy. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 70: 627-32. PMID 18577452 DOI: 10.1016/J.Ejpb.2008.05.007 |
0.354 |
|
| 2008 |
MacLean C, Moenning U, Reichel A, Fricker G. Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1249-54. PMID 18378562 DOI: 10.1124/Dmd.108.020859 |
0.348 |
|
| 2008 |
Mitschke D, Reichel A, Fricker G, Moenning U. Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1039-45. PMID 18332081 DOI: 10.1124/Dmd.107.019687 |
0.315 |
|
| 2008 |
Förster F, Volz A, Fricker G. Compound profiling for ABCC2 (MRP2) using a fluorescent microplate assay system. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 69: 396-403. PMID 18024096 DOI: 10.1016/J.Ejpb.2007.10.003 |
0.372 |
|
| 2007 |
Reichel V, Baehr C, Fricker G. From blood to brain and vice versa: transport processes in choroid plexus can be studied in vitro. Altex. 24: 53-5. PMID 19835058 |
0.362 |
|
| 2007 |
Adams M, Mahringer A, Kunert O, Fricker G, Efferth T, Bauer R. Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa. Planta Medica. 73: 1554-7. PMID 18058680 DOI: 10.1055/S-2007-993743 |
0.365 |
|
| 2007 |
Adams M, Mahringer A, Bauer R, Fricker G, Efferth T. In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii. Planta Medica. 73: 1475-8. PMID 17992628 DOI: 10.1055/S-2007-990261 |
0.411 |
|
| 2007 |
Reichel V, Masereeuw R, van den Heuvel JJ, Miller DS, Fricker G. Transport of a fluorescent cAMP analog in teleost proximal tubules. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R2382-9. PMID 17855498 DOI: 10.1152/Ajpregu.00029.2007 |
0.528 |
|
| 2007 |
Bandara S, Diehl M, Fricker G. A Mathematical Model for the Transport of Paclitaxel (Taxol) Across the Blood-Brain Barrier Chemical Engineering Research and Design. 85: 1065-1071. DOI: 10.1205/Cherd06238 |
0.456 |
|
| 2006 |
Baehr C, Reichel V, Fricker G. Choroid plexus epithelial monolayers--a cell culture model from porcine brain. Cerebrospinal Fluid Research. 3: 13. PMID 17184532 DOI: 10.1186/1743-8454-3-13 |
0.402 |
|
| 2006 |
Bubik M, Ott M, Mahringer A, Fricker G. Rapid assessment of p-glycoprotein-drug interactions at the blood-brain barrier. Analytical Biochemistry. 358: 51-8. PMID 16942742 DOI: 10.1016/J.Ab.2006.07.016 |
0.409 |
|
| 2006 |
Baehr CH, Fricker G, Miller DS. Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R464-72. PMID 16914433 DOI: 10.1152/Ajpregu.00814.2005 |
0.524 |
|
| 2006 |
Ballatori N, Henson JH, Seward DJ, Cai SY, Runnegar M, Fricker G, Miller DS, Boyer JL. Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 144: 167-79. PMID 16567119 DOI: 10.1016/J.Cbpb.2006.02.005 |
0.466 |
|
| 2006 |
Hartz AM, Bauer B, Fricker G, Miller DS. Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide. Molecular Pharmacology. 69: 462-70. PMID 16278373 DOI: 10.1124/Mol.105.017954 |
0.751 |
|
| 2005 |
Weber CC, Kressmann S, Ott M, Fricker G, Müller WE. Inhibition of P-glycoprotein function by several antidepressants may not contribute to clinical efficacy. Pharmacopsychiatry. 38: 293-300. PMID 16342001 DOI: 10.1055/S-2005-916184 |
0.338 |
|
| 2005 |
Bauer B, Hartz AM, Fricker G, Miller DS. Modulation of p-glycoprotein transport function at the blood-brain barrier. Experimental Biology and Medicine (Maywood, N.J.). 230: 118-27. PMID 15673560 DOI: 10.1177/153537020523000206 |
0.767 |
|
| 2005 |
Rothkopf C, Fahr A, Fricker G, Scherphof GL, Kamps JA. Uptake of phosphatidylserine-containing liposomes by liver sinusoidal endothelial cells in the serum-free perfused rat liver. Biochimica Et Biophysica Acta. 1668: 10-6. PMID 15670726 DOI: 10.1016/J.Bbamem.2004.10.013 |
0.335 |
|
| 2005 |
Hartz A, Bauer B, Baehr C, Miller D, Fricker G. Drug Delivery Across the Blood-Brain Barrier Current Nanoscience. 1: 203-209. DOI: 10.2174/157341305774642948 |
0.733 |
|
| 2005 |
Flaig R, Rosenkranz V, Wink M, Fricker G. Ktenate nanoparticles (bdellosomes): a novel strategy for delivering drugs to parasites or tumours Journal of Drug Delivery Science and Technology. 15: 59-63. DOI: 10.1016/S1773-2247(05)50007-8 |
0.314 |
|
| 2004 |
Bauer B, Hartz AM, Fricker G, Miller DS. Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier. Molecular Pharmacology. 66: 413-9. PMID 15322232 DOI: 10.1124/Mol.66.3 |
0.771 |
|
| 2004 |
Hartz AM, Bauer B, Fricker G, Miller DS. Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1. Molecular Pharmacology. 66: 387-94. PMID 15322229 DOI: 10.1124/Mol.104.001503 |
0.751 |
|
| 2004 |
Breen CM, Sykes DB, Baehr C, Fricker G, Miller DS. Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy. American Journal of Physiology. Renal Physiology. 287: F562-9. PMID 15126245 DOI: 10.1152/Ajprenal.00045.2003 |
0.523 |
|
| 2004 |
Fricker G, Miller DS. Modulation of drug transporters at the blood-brain barrier. Pharmacology. 70: 169-76. PMID 15001817 DOI: 10.1159/000075545 |
0.578 |
|
| 2004 |
Elferink RP, Ottenhoff R, Fricker G, Seward DJ, Ballatori N, Boyer J. Lack of biliary lipid excretion in the little skate, Raja erinacea, indicates the absence of functional Mdr2, Abcg5, and Abcg8 transporters. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G762-8. PMID 14701720 DOI: 10.1152/Ajpgi.00424.2003 |
0.343 |
|
| 2003 |
Török M, Huwyler J, Gutmann H, Fricker G, Drewe J. Modulation of transendothelial permeability and expression of ATP-binding cassette transporters in cultured brain capillary endothelial cells by astrocytic factors and cell-culture conditions. Experimental Brain Research. 153: 356-65. PMID 14610630 DOI: 10.1007/S00221-003-1620-4 |
0.372 |
|
| 2003 |
Erdlenbruch B, Alipour M, Fricker G, Miller DS, Kugler W, Eibl H, Lakomek M. Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries. British Journal of Pharmacology. 140: 1201-10. PMID 14597599 DOI: 10.1038/Sj.Bjp.0705554 |
0.52 |
|
| 2003 |
Bauer B, Miller DS, Fricker G. Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system. Pharmaceutical Research. 20: 1170-6. PMID 12948014 DOI: 10.1023/A:1025040712857 |
0.512 |
|
| 2002 |
Fellner S, Bauer B, Miller DS, Schaffrik M, Fankhänel M, Spruss T, Bernhardt G, Graeff C, Färber L, Gschaidmeier H, Buschauer A, Fricker G. Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. The Journal of Clinical Investigation. 110: 1309-18. PMID 12417570 DOI: 10.1172/Jci15451 |
0.575 |
|
| 2002 |
Fricker G, Miller DS. Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo. Pharmacology & Toxicology. 90: 5-13. PMID 12005113 DOI: 10.1034/J.1600-0773.2002.900103.X |
0.517 |
|
| 2002 |
Huwyler J, Cerletti A, Fricker G, Eberle AN, Drewe J. By-passing of P-glycoprotein using immunoliposomes. Journal of Drug Targeting. 10: 73-9. PMID 11996089 DOI: 10.1080/10611860290007559 |
0.44 |
|
| 2002 |
Fricker G. Drug transport across the blood-brain barrier. Ernst Schering Research Foundation Workshop. 139-54. PMID 11975193 DOI: 10.1007/978-3-662-04383-7_7 |
0.355 |
|
| 2002 |
Terlouw SA, Graeff C, Smeets PH, Fricker G, Russel FG, Masereeuw R, Miller DS. Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule. The Journal of Pharmacology and Experimental Therapeutics. 301: 578-85. PMID 11961059 DOI: 10.1124/Jpet.301.2.578 |
0.51 |
|
| 2002 |
Breen CM, Sykes DB, Fricker G, Miller DS. Confocal imaging of organic anion transport in intact rat choroid plexus. American Journal of Physiology. Renal Physiology. 282: F877-85. PMID 11934698 DOI: 10.1152/Ajprenal.00171.2001 |
0.502 |
|
| 2002 |
Fricker G, Nobmann S, Miller DS. Permeability of porcine blood brain barrier to somatostatin analogues. British Journal of Pharmacology. 135: 1308-14. PMID 11877340 DOI: 10.1038/Sj.Bjp.0704557 |
0.574 |
|
| 2002 |
Miller DS, Graeff C, Droulle L, Fricker S, Fricker G. Xenobiotic efflux pumps in isolated fish brain capillaries. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R191-8. PMID 11742838 DOI: 10.1152/Ajpregu.00305.2001 |
0.601 |
|
| 2002 |
Thöle M, Nobmann S, Huwyler J, Bartmann A, Fricker G. Uptake of Cationized Albumin Coupled Liposomes by Cultured Porcine Brain Microvessel Endothelial Cells and Intact Brain Capillaries Journal of Drug Targeting. 10: 337-344. DOI: 10.1080/10611860290031840 |
0.408 |
|
| 2001 |
Drewe J, Beglinger C, Fricker G. Effect of ischemia on intestinal permeability of lipopolysaccharides. European Journal of Clinical Investigation. 31: 138-44. PMID 11168452 DOI: 10.1046/J.1365-2362.2001.00792.X |
0.331 |
|
| 2001 |
Nobmann S, Bauer B, Fricker G. Ivermectin excretion by isolated functionally intact brain endothelial capillaries. British Journal of Pharmacology. 132: 722-8. PMID 11159725 DOI: 10.1038/Sj.Bjp.0703762 |
0.48 |
|
| 2000 |
Miller DS, Nobmann SN, Gutmann H, Toeroek M, Drewe J, Fricker G. Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. Molecular Pharmacology. 58: 1357-67. PMID 11093774 DOI: 10.1124/Mol.58.6.1357 |
0.598 |
|
| 2000 |
Gutmann H, Miller DS, Droulle A, Drewe J, Fahr A, Fricker G. P-glycoprotein- and mrp2-mediated octreotide transport in renal proximal tubule. British Journal of Pharmacology. 129: 251-6. PMID 10694230 DOI: 10.1038/Sj.Bjp.0703003 |
0.528 |
|
| 2000 |
Cerletti A, Drewe J, Fricker G, Eberle A, Huwyler J. Endocytosis and Transcytosis of an Immunoliposome-Based Brain Drug Delivery System Journal of Drug Targeting. 8: 435-446. DOI: 10.3109/10611860008997919 |
0.42 |
|
| 1999 |
Drewe J, Gutmann H, Fricker G, Török M, Beglinger C, Huwyler J. HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833. Biochemical Pharmacology. 57: 1147-52. PMID 11230802 DOI: 10.1016/S0006-2952(99)00026-X |
0.376 |
|
| 1999 |
Fricker G, Gutmann H, Droulle A, Drewe J, Miller DS. Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules. Pharmaceutical Research. 16: 1570-5. PMID 10554099 DOI: 10.1023/A:1018956621376 |
0.487 |
|
| 1999 |
Gutmann H, Fricker G, Drewe J, Toeroek M, Miller DS. Interactions of HIV protease inhibitors with ATP-dependent drug export proteins. Molecular Pharmacology. 56: 383-9. PMID 10419558 DOI: 10.1124/Mol.56.2.383 |
0.527 |
|
| 1999 |
Gutmann H, Fricker G, Török M, Michael S, Beglinger C, Drewe J. Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake. Pharmaceutical Research. 16: 402-7. PMID 10213371 DOI: 10.1023/A:1018825819249 |
0.402 |
|
| 1999 |
Török M, Gutmann H, Fricker G, Drewe J. Sister of P-glycoprotein expression in different tissues. Biochemical Pharmacology. 57: 833-5. PMID 10075089 DOI: 10.1016/S0006-2952(98)00357-8 |
0.422 |
|
| 1997 |
Fricker G, Wössner R, Drewe J, Fricker R, Boyer JL. Enterohepatic circulation of scymnol sulfate in an elasmobranch, the little skate (Raja erinacea). The American Journal of Physiology. 273: G1023-30. PMID 9374698 DOI: 10.1152/Ajpgi.1997.273.5.G1023 |
0.306 |
|
| 1997 |
Fricker G, Küsters E. Intestinal absorption of sugar-coupled somatostatin analogs. Journal of Pharmaceutical Sciences. 85: 1211-4. PMID 8923327 DOI: 10.1021/Js960052F |
0.337 |
|
| 1997 |
Urwyler S, Campbell E, Fricker G, Jenner P, Lemaire M, McAllister KH, Neijt HC, Park CK, Perkins M, Rudin M, Sauter A, Smith L, Wiederhold KH, Müller W. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 35: 655-69. PMID 8887975 DOI: 10.1016/0028-3908(96)84637-5 |
0.315 |
|
| 1997 |
Huwyler J, Drewe J, Klusemann C, Fricker G. Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium. British Journal of Pharmacology. 118: 1879-85. PMID 8864518 DOI: 10.1111/J.1476-5381.1996.Tb15619.X |
0.418 |
|
| 1996 |
Fricker G, Drewe J, Huwyler J, Gutmann H, Beglinger C. Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation. British Journal of Pharmacology. 118: 1841-7. PMID 8842452 DOI: 10.1111/J.1476-5381.1996.Tb15612.X |
0.42 |
|
| 1996 |
Fricker G, Fahr A, Beglinger C, Kissel T, Reiter G, Drewe J. Permeation enhancement of octreotide by specific bile salts in rats and human subjects: in vitro, in vivo correlations. British Journal of Pharmacology. 117: 217-23. PMID 8825366 DOI: 10.1111/J.1476-5381.1996.Tb15177.X |
0.345 |
|
| 1996 |
Miller DS, Fricker G, Schramm U, Henson JH, Hager DN, Nundy S, Ballatori N, Boyer JL. Active microtubule-dependent secretion of a fluorescent bile salt derivative in skate hepatocyte clusters. The American Journal of Physiology. 270: G887-96. PMID 8764193 DOI: 10.1152/Ajpgi.1996.270.6.G887 |
0.489 |
|
| 1996 |
de Fraissinette A, Kolopp M, Schiller I, Fricker G, Gammert C, Pospischil A, Vonderscher J, Richter F. In vitro tolerability of human nasal mucosa: histopathological and scanning electron-microscopic evaluation of nasal forms containing Sandostatin. Cell Biology and Toxicology. 11: 295-301. PMID 8608410 DOI: 10.1007/Bf00757627 |
0.314 |
|
| 1996 |
Oechslein CR, Fricker G, Kissel T. Nasal delivery of octreotide: Absorption enhancement by particulate carrier systems International Journal of Pharmaceutics. 139: 25-32. DOI: 10.1016/0378-5173(96)04569-3 |
0.308 |
|
| 1995 |
Schramm U, Fricker G, Wenger R, Miller DS. P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules. The American Journal of Physiology. 268: F46-52. PMID 7840247 DOI: 10.1152/Ajprenal.1995.268.1.F46 |
0.487 |
|
| 1995 |
Fahr A, Holz M, Fricker G. Liposomal Formulations of Cyclosporin A: Influence of Lipid Type and Dose on Pharmacokinetics Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1189-1198. PMID 7494833 DOI: 10.1023/A:1016220211925 |
0.323 |
|
| 1994 |
Jaehde U, Masereeuw R, De Boer AG, Fricker G, Nagelkerke JF, Vonderscher J, Breimer DD. Quantification and visualization of the transport of octreotide, a somatostatin analogue, across monolayers of cerebrovascular endothelial cells. Pharmaceutical Research. 11: 442-8. PMID 8008714 DOI: 10.1023/A:1018929508018 |
0.424 |
|
| 1994 |
Fricker G, Dubost V, Finsterwald K, Boyer JL. Characteristics of bile salt uptake into skate hepatocytes Biochemical Journal. 299: 665-670. DOI: 10.1042/Bj2990665 |
0.315 |
|
| 1993 |
Drewe J, Fricker G, Vonderscher J, Beglinger C. Enteral absorption of octreotide: absorption enhancement by polyoxyethylene-24-cholesterol ether. British Journal of Pharmacology. 108: 298-303. PMID 8448581 DOI: 10.1111/J.1476-5381.1993.Tb12799.X |
0.359 |
|
| 1991 |
Fricker G, Bruns C, Munzer J, Briner U, Albert R, Kissel T, Vonderscher J. Intestinal absorption of the octapeptide SMS 201-995 visualized by fluorescence derivatization. Gastroenterology. 100: 1544-52. PMID 2019360 DOI: 10.1016/0016-5085(91)90651-Z |
0.334 |
|
| 1989 |
Fricker G, Landmann L, Meier PJ. Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocytes Journal of Clinical Investigation. 84: 876-885. PMID 2760217 DOI: 10.1172/Jci114248 |
0.342 |
|
| 1988 |
Fricker G, Schneider S, Gerok W, Kurz G. Identification of different transport systems for bile salts in sinusoidal and canalicular membranes of hepatocytes. Biological Chemistry Hoppe-Seyler. 368: 1143-50. PMID 3675867 DOI: 10.1515/Bchm3.1987.368.2.1143 |
0.335 |
|
| 1987 |
Hugentobler G, Fricker G, Boyer JL, Meier PJ. Anion transport in basolateral (sinusoidal) liver plasma-membrane vesicles of the little skate (Raja erinacea) Biochemical Journal. 247: 589-595. PMID 3426551 DOI: 10.1042/Bj2470589 |
0.318 |
|
| 1987 |
Fricker G, Hugentobler G, Meier PJ, Kurz G, Boyer JL. Identification of a single sinusoidal bile salt uptake system in skate liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 253. PMID 3425718 DOI: 10.1152/Ajpgi.1987.253.6.G816 |
0.348 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Uhl P, Grundmann C, Sauter M, Storck P, Tursch A, Özbek S, Leotta K, Roth R, Witzigmann D, Kulkarni JA, Fidelj V, Kleist C, Cullis PR, Fricker G, Mier W. Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide. Nanomedicine : Nanotechnology, Biology, and Medicine. 102132. PMID 31783138 DOI: 10.1016/J.Nano.2019.102132 |
0.3 |
|
| 2012 |
Mahringer A, Reichel V, Ott M, MacLean C, Reimold I, Hollnack-Pusch E, Fricker G. Overcoming the blood brain barrier - The challenge of brain drug targeting Journal of Nanoneuroscience. 2: 5-19. DOI: 10.1166/jns.2012.1012 |
0.297 |
|
| 1984 |
Wieland T, Nassal M, Kramer W, Fricker G, Bickel U, Kurz G. Identity of hepatic membrane transport systems for bile salts, phalloidin, and antamanide by photoaffinity labeling. Proceedings of the National Academy of Sciences of the United States of America. 81: 5232-6. PMID 6591186 DOI: 10.1073/Pnas.81.16.5232 |
0.296 |
|
| 2010 |
MacLean C, Moenning U, Reichel A, Fricker G. Regional absorption of fexofenadine in rat intestine. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 41: 670-4. PMID 20869437 DOI: 10.1016/J.Ejps.2010.09.007 |
0.296 |
|
| 2020 |
Sironi D, Bauer-Brandl A, Brandl M, Rosenberg J, Fricker G. The Influence of Liquid Intake on the Performance of an Amorphous Solid Dispersion in Rats. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 32470638 DOI: 10.1016/J.Ejpb.2020.05.021 |
0.295 |
|
| 2022 |
Puris E, Auriola S, Petralla S, Hartman R, Gynther M, de Lange ECM, Fricker G. Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model. Neurobiology of Disease. 105741. PMID 35472634 DOI: 10.1016/j.nbd.2022.105741 |
0.295 |
|
| 2019 |
Stremmel W, Staffer S, Fricker G, Weiskirchen R. The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2. International Journal of Molecular Sciences. 20. PMID 31717968 DOI: 10.3390/Ijms20225631 |
0.294 |
|
| 2023 |
Hartl N, Gabold B, Adams F, Uhl P, Oerter S, Gätzner S, Metzger M, König AC, Hauck SM, Appelt-Menzel A, Mier W, Fricker G, Merkel OM. Overcoming the blood-brain barrier? - prediction of blood-brain permeability of hydrophobically modified polyethylenimine polyplexes for siRNA delivery into the brain with in vitro and in vivo models. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 37437848 DOI: 10.1016/j.jconrel.2023.07.019 |
0.293 |
|
| 2021 |
Mahringer A, Puris E, Fricker G. Crossing the blood-brain barrier: A review on drug delivery strategies using colloidal carrier systems. Neurochemistry International. 147: 105017. PMID 33887377 DOI: 10.1016/j.neuint.2021.105017 |
0.293 |
|
| 2015 |
Gartzke D, Delzer J, Laplanche L, Uchida Y, Hoshi Y, Tachikawa M, Terasaki T, Sydor J, Fricker G. Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases. Pharmaceutical Research. 32: 2060-71. PMID 25522789 DOI: 10.1007/S11095-014-1599-5 |
0.293 |
|
| 2013 |
Hüsch J, Bohnet J, Fricker G, Skarke C, Artaria C, Appendino G, Schubert-Zsilavecz M, Abdel-Tawab M. Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract. Fitoterapia. 84: 89-98. PMID 23092618 DOI: 10.1016/J.Fitote.2012.10.002 |
0.291 |
|
| 2010 |
Tho I, Liepold B, Rosenberg J, Maegerlein M, Brandl M, Fricker G. Formation of nano/micro-dispersions with improved dissolution properties upon dispersion of ritonavir melt extrudate in aqueous media European Journal of Pharmaceutical Sciences. 40: 25-32. PMID 20172027 DOI: 10.1016/J.Ejps.2010.02.003 |
0.291 |
|
| 2001 |
Fricker G. Oral Drug Absorption: Prediction and Assessment Jennifer Dressman, Hans Lennernäs (editors), Marcel Dekker Inc., New York, Basel, pp. 330, ISBN 0-8247-0272-7 European Journal of Pharmaceutics and Biopharmaceutics. 52: 97-98. DOI: 10.1016/S0939-6411(01)00143-6 |
0.29 |
|
| 1996 |
Drewe J, Huwyler J, Fricker G, Behrens U, Beglinger C. Are CCK-8 effects on food-intake mediated via direct access to the brain? Regulatory Peptides. 64: 36. DOI: 10.1016/0167-0115(96)87793-7 |
0.288 |
|
| 1995 |
Billich A, Charpiot B, Fricker G, Gstach H, Lehr P, Peichl P, Scholz D, Rosenwirth B. HIV proteinase inhibitors containing 2-aminobenzylstatine as a novel scissile bond replacement: biochemical and pharmacological characterization. Antiviral Research. 25: 215-33. PMID 7710270 DOI: 10.1016/0166-3542(94)90005-1 |
0.287 |
|
| 2000 |
Michael S, Thöle M, Dillmann R, Fahr A, Drewe J, Fricker G. Improvement of intestinal peptide absorption by a synthetic bile acid derivative, cholylsarcosine. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 10: 133-40. PMID 10727879 DOI: 10.1016/S0928-0987(99)00093-7 |
0.286 |
|
| 2016 |
Loureiro JA, Gomes B, Fricker G, Coelho MA, Rocha S, Pereira MC. Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment. Colloids and Surfaces. B, Biointerfaces. 145: 8-13. PMID 27131092 DOI: 10.1016/j.colsurfb.2016.04.041 |
0.284 |
|
| 2002 |
Ritter M, Buechler C, Boettcher A, Barlage S, Schmitz-Madry A, Orsó E, Bared SM, Schmiedeknecht G, Baehr CH, Fricker G, Schmitz G. Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I. Genomics. 79: 693-702. PMID 11991719 DOI: 10.1006/Geno.2002.6761 |
0.284 |
|
| 2015 |
Loureiro JA, Gomes B, Fricker G, Cardoso I, Ribeiro CA, Gaiteiro C, Coelho MA, Pereira Mdo C, Rocha S. Dual ligand immunoliposomes for drug delivery to the brain. Colloids and Surfaces. B, Biointerfaces. 134: 213-9. PMID 26204501 DOI: 10.1016/j.colsurfb.2015.06.067 |
0.284 |
|
| 2021 |
Sayed Hanafy A, Dietrich D, Fricker G, Lamprecht A. Blood-brain barrier models: rationale for selection. Advanced Drug Delivery Reviews. 113859. PMID 34246710 DOI: 10.1016/j.addr.2021.113859 |
0.284 |
|
| 2013 |
Curić A, Reul R, Möschwitzer J, Fricker G. Formulation optimization of itraconazole loaded PEGylated liposomes for parenteral administration by using design of experiments. International Journal of Pharmaceutics. 448: 189-97. PMID 23524086 DOI: 10.1016/J.Ijpharm.2013.03.029 |
0.283 |
|
| 2023 |
Puris E, Fricker G, Gynther M. The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy. Pharmaceutics. 15. PMID 36839686 DOI: 10.3390/pharmaceutics15020364 |
0.282 |
|
| 2011 |
Parmentier J, Hartmann FJ, Fricker G. Corrigendum to “In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules” European Journal of Pharmaceutics and Biopharmaceutics. 78: 539. DOI: 10.1016/J.Ejpb.2011.03.020 |
0.277 |
|
| 2007 |
Järve A, Müller J, Kim IH, Rohr K, MacLean C, Fricker G, Massing U, Eberle F, Dalpke A, Fischer R, Trendelenburg MF, Helm M. Surveillance of siRNA integrity by FRET imaging. Nucleic Acids Research. 35: e124. PMID 17890733 DOI: 10.1093/Nar/Gkm694 |
0.277 |
|
| 2022 |
Bolten JS, Pratsinis A, Alter CL, Fricker G, Huwyler J. Zebrafish () larva as an in vivo vertebrate model to study renal function. American Journal of Physiology. Renal Physiology. 322: F280-F294. PMID 35037468 DOI: 10.1152/ajprenal.00375.2021 |
0.276 |
|
| 2006 |
Sauer SW, Okun JG, Fricker G, Mahringer A, Müller I, Crnic LR, Mühlhausen C, Hoffmann GF, Hörster F, Goodman SI, Harding CO, Koeller DM, Kölker S. Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency. Journal of Neurochemistry. 97: 899-910. PMID 16573641 DOI: 10.1111/J.1471-4159.2006.03813.X |
0.275 |
|
| 2017 |
Stremmel W, Schmidt KV, Schuhmann V, Kratzer F, Garbade SF, Langhans CD, Fricker G, Okun JG. Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine. Plos One. 12: e0170742. PMID 28129384 DOI: 10.1371/Journal.Pone.0170742 |
0.274 |
|
| 1997 |
Fricker G, Drewe J. Current concepts in intestinal peptide absorption. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 195-211. PMID 9231327 DOI: 10.1002/Psc.66 |
0.27 |
|
| 2023 |
Hartinger EM, Mahringer A, Choudhuri SK, Fricker G, Efferth T. Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines. Anticancer Research. 43: 1031-1041. PMID 36854510 DOI: 10.21873/anticanres.16248 |
0.27 |
|
| 2003 |
Fricker G. “Pharmacokinetics in Drug Discovery and Development” Ronald D. Schoenwald (Ed.); RCR Press, Boca Raton, London, New York, Washington; 2002, 426 pages, ISBN 1-5667-6973-6, US$ 59.95 European Journal of Pharmaceutics and Biopharmaceutics. 55: 141-142. DOI: 10.1016/S0939-6411(02)00154-6 |
0.269 |
|
| 1993 |
Albert R, Marbach P, Bauer W, Briner U, Fricker G, Bruns C, Pless J. SDZ CO 611: a highly potent glycated analog of somatostatin with improved oral activity. Life Sciences. 53: 517-25. PMID 8341138 DOI: 10.1016/0024-3205(93)90703-6 |
0.268 |
|
| 1996 |
Haeberlin B, Gengenbacher T, Meinzer A, Fricker G. Cyclodextrins — Useful excipients for oral peptide administration? International Journal of Pharmaceutics. 137: 103-110. DOI: 10.1016/0378-5173(96)04499-7 |
0.268 |
|
| 2010 |
Ofokansi K, Winter G, Fricker G, Coester C. Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 76: 1-9. PMID 20420904 DOI: 10.1016/J.Ejpb.2010.04.008 |
0.268 |
|
| 2022 |
Oezen G, Schentarra EM, Bolten JS, Huwyler J, Fricker G. Sodium arsenite but not aluminum chloride stimulates ABC transporter activity in renal proximal tubules of killifish (Fundulus heteroclitus). Aquatic Toxicology (Amsterdam, Netherlands). 252: 106314. PMID 36201872 DOI: 10.1016/j.aquatox.2022.106314 |
0.267 |
|
| 2009 |
Fricker G. European Journal of Pharmaceutics and Biopharmaceutics. 72: 285. DOI: 10.1016/J.Ejpb.2008.12.010 |
0.266 |
|
| 2007 |
Fricker G. European Journal of Pharmaceutics and Biopharmaceutics. 67: 779. DOI: 10.1016/J.Ejpb.2007.07.007 |
0.266 |
|
| 2010 |
Kanzer J, Hupfeld S, Vasskog T, Tho I, Hölig P, Mägerlein M, Fricker G, Brandl M. In situ formation of nanoparticles upon dispersion of melt extrudate formulations in aqueous medium assessed by asymmetrical flow field-flow fractionation Journal of Pharmaceutical and Biomedical Analysis. 53: 359-365. PMID 20447794 DOI: 10.1016/J.Jpba.2010.04.012 |
0.264 |
|
| 2019 |
Schirrmacher R, Bailey JJ, Mossine AV, Scott PJH, Kaiser L, Bartenstein P, Lindner S, Kaplan DR, Kostikov A, Fricker G, Mahringer A, Rosa-Neto P, Schirrmacher E, Wängler C, Wängler B, et al. Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging. Pharmaceuticals (Basel, Switzerland). 12. PMID 30609832 DOI: 10.3390/Ph12010007 |
0.262 |
|
| 2018 |
Vall-Sagarra A, Litau S, Decristoforo C, Wängler B, Schirrmacher R, Fricker G, Wängler C. Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging? Pharmaceuticals (Basel, Switzerland). 11. PMID 29973529 DOI: 10.3390/Ph11030065 |
0.262 |
|
| 2015 |
Litau S, Niedermoser S, Vogler N, Roscher M, Schirrmacher R, Fricker G, Wängler B, Wängler C. Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics. Bioconjugate Chemistry. 26: 2350-2359. PMID 26420336 DOI: 10.1021/Acs.Bioconjchem.5B00510 |
0.26 |
|
| 2012 |
Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M. The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility. International Journal of Nanomedicine. 7: 5757-68. PMID 23166440 DOI: 10.2147/Ijn.S36571 |
0.258 |
|
| 2017 |
Furtmann B, Tang J, Kramer S, Eickner T, Luderer F, Fricker G, Gomez A, Heemskerk B, Jähn PS. Electrospray synthesis of PLGA nanoparticles encapsulating peptides to enhance proliferation of antigen-specific CD8(+) T cells. Journal of Pharmaceutical Sciences. PMID 28652156 DOI: 10.1016/J.Xphs.2017.06.013 |
0.257 |
|
| 2020 |
Judmann B, Braun D, Wängler B, Schirrmacher R, Fricker G, Wängler C. Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy. Pharmaceuticals (Basel, Switzerland). 13. PMID 32751666 DOI: 10.3390/Ph13080173 |
0.255 |
|
| 2011 |
Berger FI, Feld J, Bertow D, Eisenbrand G, Fricker G, Gerhardt N, Merz KH, Richling E, Baum M. Biological effects of acrylamide after daily ingestion of various foods in comparison to water: a study in rats. Molecular Nutrition & Food Research. 55: 387-99. PMID 20938989 DOI: 10.1002/Mnfr.201000234 |
0.255 |
|
| 2017 |
Bernard-Gauthier V, Mahringer A, Vesnaver M, Fricker G, Schirrmacher R. Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development. Bioorganic & Medicinal Chemistry Letters. PMID 28476569 DOI: 10.1016/J.Bmcl.2017.04.064 |
0.253 |
|
| 2014 |
Uhl P, Fricker G, Haberkorn U, Mier W. Current status in the therapy of liver diseases. International Journal of Molecular Sciences. 15: 7500-12. PMID 24786290 DOI: 10.3390/Ijms15057500 |
0.252 |
|
| 2012 |
Anhalt K, Geissler S, Harms M, Weigandt M, Fricker G. Development of a new method to assess nanocrystal dissolution based on light scattering. Pharmaceutical Research. 29: 2887-901. PMID 22688901 DOI: 10.1007/S11095-012-0795-4 |
0.25 |
|
| 2023 |
Ozgür B, Puris E, Brachner A, Appelt-Menzel A, Oerter S, Balzer V, Holst MR, Christiansen RF, Hyldig K, Buckley ST, Kristensen M, Auriola S, Jensen A, Fricker G, Nielsen MS, et al. Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line. Fluids and Barriers of the Cns. 20: 96. PMID 38115090 DOI: 10.1186/s12987-023-00501-9 |
0.249 |
|
| 2019 |
Tremmel R, Helm F, Wupperfeld D, Fricker G, Stremmel W. Delivery of Copper-chelating Trientine (TETA) to the central nervous system Zeitschrift Fur Gastroenterologie. 57. DOI: 10.1055/S-0038-1677153 |
0.248 |
|
| 2013 |
Zadeh-Khorasani M, Nolte T, Mueller TD, Pechlivanis M, Rueff F, Wollenberg A, Fricker G, Wolf E, Siebeck M, Gropp R. NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways. Journal of Translational Medicine. 11: 4. PMID 23294516 DOI: 10.1186/1479-5876-11-4 |
0.245 |
|
| 2006 |
Fricker G. Blood–Brain Barriers: From Ontogeny to Artificial Interfaces. Edited by Rolf Dermietzel, David C. Spray, and Maiken Nedergaard. Chemmedchem. 1: 1282-1283. DOI: 10.1002/Cmdc.200600131 |
0.244 |
|
| 2015 |
Litau S, Seibold U, Vall-Sagarra A, Fricker G, Wängler B, Wängler C. Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments. Chemmedchem. 10: 1200-8. PMID 26011290 DOI: 10.1002/Cmdc.201500132 |
0.237 |
|
| 2015 |
Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier Pharmaceutical Research. DOI: 10.1007/s11095-015-1679-1 |
0.235 |
|
| 2022 |
Puris E, Saveleva L, Górová V, Vartiainen P, Kortelainen M, Lamberg H, Sippula O, Malm T, Jalava PI, Auriola S, Fricker G, Kanninen KM. Air pollution exposure increases ABCB1 and ASCT1 transporter levels in mouse cortex. Environmental Toxicology and Pharmacology. 96: 104003. PMID 36283621 DOI: 10.1016/j.etap.2022.104003 |
0.233 |
|
| 2004 |
Weber CC, Kressmann S, Fricker G, Müller WE. Modulation of P-glycoprotein function by St John's wort extract and its major constituents. Pharmacopsychiatry. 37: 292-8. PMID 15551196 DOI: 10.1055/s-2004-832686 |
0.233 |
|
| 2020 |
Lüchtenborg C, Niederhaus B, Brügger B, Popovic B, Fricker G. Lipid Profiles of Five Essential Phospholipid Preparations for the Treatment of Nonalcoholic Fatty Liver Disease: A Comparative Study. Lipids. PMID 32255515 DOI: 10.1002/Lipd.12236 |
0.23 |
|
| 2018 |
Prause M, Niedermoser S, Wängler C, Decristoforo C, Seibold U, Riester S, Taguchi T, Schirrmacher R, Fricker G, Wängler B. Synthesis, in vitro and in vivo evaluation of F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors. Nuclear Medicine and Biology. 57: 1-11. PMID 29175467 DOI: 10.1016/J.Nucmedbio.2017.11.004 |
0.225 |
|
| 2023 |
Hartl N, Gabold B, Uhl P, Kromer A, Xiao X, Fricker G, Mier W, Liu R, Merkel OM. ApoE-functionalization of nanoparticles for targeted brain delivery-a feasible method for polyplexes? Drug Delivery and Translational Research. PMID 38087181 DOI: 10.1007/s13346-023-01482-w |
0.225 |
|
| 1993 |
Bossard R, Stieger B, O'Neill B, Fricker G, Meier PJ. Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver Journal of Clinical Investigation. 91: 2714-2720. PMID 8514879 DOI: 10.1172/JCI116511 |
0.224 |
|
| 2000 |
Monella D, Sommer K, Fricker G, Völker U. Vergleichende Untersuchungen zur Teilchengrößenanalyse Chemie Ingenieur Technik. 72: 273-276. DOI: 10.1002/1522-2640(200003)72:3<273::Aid-Cite273>3.0.Co;2-N |
0.224 |
|
| 2002 |
Fricker G. Biologically Active Peptides: Design, Synthesis and Utilization W.V. Williams, D.B. Weiner (editors), Technomic Publishing Co., Inc., Lancaster, Basel, pp. 360, ISBN 0-87762-935-8 European Journal of Pharmaceutics and Biopharmaceutics. 53: 133-134. DOI: 10.1016/S0939-6411(01)00211-9 |
0.218 |
|
| 2020 |
Moayedi S, Yadegar A, Balalaie S, Yarmohammadi M, Zali MR, Suzuki H, Fricker G, Haririan I. Sugar Codes Conjugated Alginate: An Innovative Platform to Make a Strategic Breakthrough in Simultaneous Prophylaxis of GERD and Infection. Drug Design, Development and Therapy. 14: 2405-2412. PMID 32606607 DOI: 10.2147/Dddt.S255611 |
0.217 |
|
| 2023 |
Puris E, Petralla S, Auriola S, Kidron H, Fricker G, Gynther M. Monoacylglycerol Lipase Inhibitor JJKK048 Ameliorates ABCG2 Transporter-Mediated Regorafenib Resistance Induced by Hypoxia in Triple Negative Breast Cancer Cells. Journal of Pharmaceutical Sciences. PMID 37220829 DOI: 10.1016/j.xphs.2023.05.012 |
0.214 |
|
| 2024 |
Werner J, Umstätter F, Hertlein T, Mühlberg E, Beijer B, Wohlfart S, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P. Oral Delivery of the Vancomycin Derivative FU002 by a Surface-Modified Liposomal Nanocarrier. Advanced Healthcare Materials. e2303654. PMID 38387090 DOI: 10.1002/adhm.202303654 |
0.212 |
|
| 2021 |
Lechner C, Mönning U, Reichel A, Fricker G. Potential and Limits of Kidney Cells for Evaluation of Renal Excretion. Pharmaceuticals (Basel, Switzerland). 14. PMID 34577608 DOI: 10.3390/ph14090908 |
0.21 |
|
| 2021 |
Mühlberg E, Burtscher M, Umstätter F, Fricker G, Mier W, Uhl P. Trends in liposomal nanocarrier strategies for the oral delivery of biologics. Nanomedicine (London, England). 16: 1813-1832. PMID 34269068 DOI: 10.2217/nnm-2021-0177 |
0.206 |
|
| 2017 |
Disch L, Forsch K, Siewert B, Drewe J, Fricker G. In vitro and in situ characterization of triterpene glycosides from Cimicifuga racemosa extract. Journal of Pharmaceutical Sciences. PMID 28827038 DOI: 10.1016/J.Xphs.2017.07.023 |
0.205 |
|
| 2004 |
Fricker G, Miller DS, Sharma JN, Abbas SA, Yusof APM, Shah RP, Yalcin M, Savci V, Zernig G, Wit HD, Telser S, Nienhusmeier M, Wakonigg G, Sturm K, Berger I, et al. Contents Vol. 70, 2004 Pharmacology. 70: 221-222. DOI: 10.1159/000077143 |
0.203 |
|
| 2021 |
Nair AL, Mesch L, Schulz I, Becker H, Raible J, Kiessling H, Werner S, Rothbauer U, Schmees C, Busche M, Trennheuser S, Fricker G, Stelzle M. Parallelizable Microfluidic Platform to Model and Assess In Vitro Cellular Barriers: Technology and Application to Study the Interaction of 3D Tumor Spheroids with Cellular Barriers. Biosensors. 11. PMID 34562904 DOI: 10.3390/bios11090314 |
0.199 |
|
| 2005 |
Fricker G. Overcoming MDR at the blood–brain barrier International Congress Series. 1277: 131-143. DOI: 10.1016/J.ICS.2005.02.018 |
0.196 |
|
| 2023 |
Werner J, Umstätter F, Hertlein T, Beijer B, Kleist C, Mühlberg E, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P. Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier. Nanomedicine : Nanotechnology, Biology, and Medicine. 56: 102731. PMID 38158147 DOI: 10.1016/j.nano.2023.102731 |
0.192 |
|
| 2017 |
Disch L, Drewe J, Fricker G. Dissolution Testing of Herbal Medicines: Challenges and Regulatory Standards in Europe, the United States, Canada, and Asia Dissolution Technologies. 24: 6-12. DOI: 10.14227/Dt240217P6 |
0.189 |
|
| 2022 |
Puris E, Kouřil Š, Najdekr L, Auriola S, Loppi S, Korhonen P, Gómez-Budia M, Fricker G, Kanninen KM, Malm T, Friedecký D, Gynther M. Metabolomic, lipidomic and proteomic characterisation of lipopolysaccharide-induced inflammation mouse model. Neuroscience. PMID 35636730 DOI: 10.1016/j.neuroscience.2022.05.030 |
0.186 |
|
| 2022 |
Wupperfeld D, Fricker G, Bois De Fer B, Frank L, Wehrle A, Popovic B. Essential phospholipids decrease apoptosis and increase membrane transport in human hepatocyte cell lines. Lipids in Health and Disease. 21: 91. PMID 36153592 DOI: 10.1186/s12944-022-01698-8 |
0.184 |
|
| 2020 |
Schmitt MV, Reichel A, Liu X, Fricker G, Lienau P. Extension of the mechanistic tissue distribution model of Rodgers & Rowland by systematic incorporation of lysosomal trapping: impact on Kpu and volume of distribution predictions in the rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 33148688 DOI: 10.1124/dmd.120.000161 |
0.183 |
|
| 1987 |
Ruetz S, Fricker G, Hugentobler G, Winterhalter K, Kurz G, Meier PJ. Isolation and characterization of the putative canalicular bile salt transport system of rat liver. Journal of Biological Chemistry. 262: 11324-11330. DOI: 10.1016/S0021-9258(18)60962-7 |
0.176 |
|
| 2018 |
Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M. Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. Fluids and Barriers of the Cns. 15: 3. PMID 29329565 DOI: 10.1186/s12987-017-0086-x |
0.175 |
|
| 2004 |
Fricker G, Miller DS, Sharma JN, Abbas SA, Yusof APM, Shah RP, Yalcin M, Savci V, Zernig G, Wit HD, Telser S, Nienhusmeier M, Wakonigg G, Sturm K, Berger I, et al. Subject Index Vol. 70, 2004 Pharmacology. 70: 217-220. DOI: 10.1159/000077142 |
0.169 |
|
| 1986 |
Kröncke KD, Fricker G, Meier PJ, Gerok W, Wieland T, Kurz G. alpha-Amanitin uptake into hepatocytes. Identification of hepatic membrane transport systems used by amatoxins. Journal of Biological Chemistry. 261: 12562-12567. DOI: 10.1016/s0021-9258(18)67125-x |
0.166 |
|
| 2023 |
Eteläinen TS, Silva MC, Uhari-Väänänen JK, De Lorenzo F, Jäntti MH, Cui H, Chavero-Pieres M, Kilpeläinen T, Mechtler C, Svarcbahs R, Seppälä E, Savinainen JR, Puris E, Fricker G, Gynther M, et al. A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy. Science Translational Medicine. 15: eabq2915. PMID 37043557 DOI: 10.1126/scitranslmed.abq2915 |
0.159 |
|
| 2021 |
Uhl P, Sauter M, Hertlein T, Witzigmann D, Laffleur F, Hofhaus G, Fidelj V, Tursch A, Özbek S, Hopke E, Haberkorn U, Bernkop‐Schnürch A, Ohlsen K, Fricker G, Mier W. Overcoming the Mucosal Barrier: Tetraether Lipid‐Stabilized Liposomal Nanocarriers Decorated with Cell‐Penetrating Peptides Enable Oral Delivery of Vancomycin Advanced Therapeutics. 4: 2000247. DOI: 10.1002/adtp.202000247 |
0.15 |
|
| 1996 |
Billich A, Fricker G, Müller I, Donatsch P, Ettmayer P, Gstach H, Lehr P, Peichl P, Scholz D, Rosenwirth B. SDZ PRI 053, an orally bioavailable human immunodeficiency virus type 1 proteinase inhibitor containing the 2-aminobenzylstatine moiety. Antimicrobial Agents and Chemotherapy. 39: 1406-13. PMID 7492076 DOI: 10.1128/AAC.39.7.1406 |
0.147 |
|
| 2022 |
Gynther M, Estrada ML, Loppi S, Korhonen P, Kanninen KM, Malm T, Koistinaho J, Auriola S, Fricker G, Puris E. Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer's Disease. Pharmaceutics. 14. PMID 36365256 DOI: 10.3390/pharmaceutics14112438 |
0.137 |
|
| 1999 |
Török M, Gutmann H, Fricker G, Drewe J. Sister of P-glycoprotein expression in different tissues Biochemical Pharmacology. 57: 833-835. DOI: 10.1016/S0006-2952(98)00357-8 |
0.134 |
|
| 2022 |
Judmann B, Braun D, Schirrmacher R, Wängler B, Fricker G, Wängler C. Toward the Development of GE11-Based Radioligands for Imaging of Epidermal Growth Factor Receptor-Positive Tumors. Acs Omega. 7: 27690-27702. PMID 35967067 DOI: 10.1021/acsomega.2c03407 |
0.132 |
|
| 2023 |
Braun D, Judmann B, Cheng X, Wängler B, Schirrmacher R, Fricker G, Wängler C. Synthesis, Radiolabeling, and and Characterization of Heterobivalent Peptidic Agents for Bispecific EGFR and Integrin αβ Targeting. Acs Omega. 8: 2793-2807. PMID 36687076 DOI: 10.1021/acsomega.2c07484 |
0.129 |
|
| 2024 |
Puris E, Saveleva L, Auriola S, Gynther M, Kanninen KM, Fricker G. Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease. Frontiers in Pharmacology. 15: 1365051. PMID 38572427 DOI: 10.3389/fphar.2024.1365051 |
0.12 |
|
| 2024 |
Albertini C, Petralla S, Massenzio F, Monti B, Rizzardi N, Bergamini C, Uliassi E, Borges F, Chavarria D, Fricker G, Goettert M, Kronenberger T, Gehringer M, Laufer S, Bolognesi ML. Targeting Lewy body dementia with neflamapimod-rasagiline hybrids. Archiv Der Pharmazie. e2300525. PMID 38412454 DOI: 10.1002/ardp.202300525 |
0.12 |
|
| 2024 |
Petralla S, Saveleva L, Kanninen KM, Oster JS, Panayotova M, Fricker G, Puris E. Increased Expression of Transferrin Receptor 1 in the Brain Cortex of 5xFAD Mouse Model of Alzheimer's Disease Is Associated with Activation of HIF-1 Signaling Pathway. Molecular Neurobiology. PMID 38296900 DOI: 10.1007/s12035-024-03990-3 |
0.12 |
|
| 2021 |
Cheng X, Hübner R, von Kiedrowski V, Fricker G, Schirrmacher R, Wängler C, Wängler B. Design, Synthesis, In Vitro and In Vivo Evaluation of Heterobivalent SiFA-Modified Peptidic Radioligands Targeting Both Integrin αβ and the MC1 Receptor-Suitable for the Specific Visualization of Melanomas? Pharmaceuticals (Basel, Switzerland). 14. PMID 34200477 DOI: 10.3390/ph14060547 |
0.119 |
|
| 2021 |
Damerow H, Hübner R, Judmann B, Schirrmacher R, Wängler B, Fricker G, Wängler C. Side-by-Side Comparison of Five Chelators for Zr-Labeling of Biomolecules: Investigation of Chemical/Radiochemical Properties and Complex Stability. Cancers. 13. PMID 34944969 DOI: 10.3390/cancers13246349 |
0.114 |
|
| 2023 |
Judmann B, Wängler B, Schirrmacher R, Fricker G, Wängler C. Towards Radiolabeled EGFR-Specific Peptides: Alternatives to GE11. Pharmaceuticals (Basel, Switzerland). 16. PMID 37259420 DOI: 10.3390/ph16020273 |
0.113 |
|
| 2022 |
Keller BL, Lohmann CA, Kyeremateng SO, Fricker G. Synthesis and Characterization of Biodegradable Poly(butyl cyanoacrylate) for Drug Delivery Applications. Polymers. 14. PMID 35267821 DOI: 10.3390/polym14050998 |
0.108 |
|
| 2022 |
Damerow H, Cheng X, von Kiedrowski V, Schirrmacher R, Wängler B, Fricker G, Wängler C. Toward Optimized Zr-Immuno-PET: Side-by-Side Comparison of [Zr]Zr-DFO-, [Zr]Zr-3,4,3-(LI-1,2-HOPO)- and [Zr]Zr-DFO*-Cetuximab for Tumor Imaging: Which Chelator Is the Most Suitable? Pharmaceutics. 14. PMID 36297549 DOI: 10.3390/pharmaceutics14102114 |
0.107 |
|
| 2023 |
Bolten JS, Mancuso RV, Roos NJ, Mayr A, Puligilla RD, Kraus L, Odermatt A, Fricker G, Huwyler J. Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models. Toxicology and Applied Pharmacology. 116493. PMID 36977437 DOI: 10.1016/j.taap.2023.116493 |
0.102 |
|
| 2022 |
Zoeller MP, Hafiz S, Marx A, Erwin N, Fricker G, Carpenter JF. Exploring the protein stabilizing capability of surfactants against agitation stress and the underlying mechanisms. Journal of Pharmaceutical Sciences. PMID 36096287 DOI: 10.1016/j.xphs.2022.09.004 |
0.084 |
|
| 2022 |
Banik N, Braun S, Gerit Brandenburg J, Fricker G, Kalonia DS, Rosenkranz T. Technology development to evaluate the effectiveness of viscosity reducing excipients. International Journal of Pharmaceutics. 626: 122204. PMID 36116691 DOI: 10.1016/j.ijpharm.2022.122204 |
0.083 |
|
| 2022 |
Damerow H, Wängler B, Schirrmacher R, Fricker G, Wängler C. Synthesis of a Bifunctional Cross-Bridged Chelating Agent, Peptide Conjugation, and Comparison of Ga Labeling and Complex Stability Characteristics with Established Chelators. Chemmedchem. e202200495. PMID 36259364 DOI: 10.1002/cmdc.202200495 |
0.042 |
|
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